CN104984038A - Oral Chinese herb preparation treating post-traumatic brain syndrome and preparing method - Google Patents

Oral Chinese herb preparation treating post-traumatic brain syndrome and preparing method Download PDF

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CN104984038A
CN104984038A CN201510495893.6A CN201510495893A CN104984038A CN 104984038 A CN104984038 A CN 104984038A CN 201510495893 A CN201510495893 A CN 201510495893A CN 104984038 A CN104984038 A CN 104984038A
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陈双成
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Abstract

The invention discloses an oral Chinese herb preparation treating the post-traumatic brain syndrome. The oral Chinese herb preparation is prepared from, by weight, 3-9 parts of ligusticum wallichii, 5-9 parts of the root of delavay schefflera, 1-5 parts of pseudo-ginseng, 2-6 parts of dipsacus root, 1-3 parts of lucid ganoderma, 3-7 parts of calamus, 4-6 parts of red flower, 2-4 parts of platycodon grandiflorum, 5-15 parts of centella, 5-9 parts of longan, 3-6 parts of lily, 1-3 parts of mulberry, 6-10 parts of semen sesami nigrum, 10-20 parts of soybean and 10-15 parts of semen juglandis. The oral Chinese herb preparation has the obvious effect on treating the post-traumatic brain syndrome, the symptoms such as headache, insomnia, dreaminess, tinnitus, palpitation, hidrosis and inattention caused by the post-traumatic brain syndrome can be well relieved. Common local medicine materials are selected, price is low, and the economical burden on patients is relieved.

Description

A kind of oral traditional Chinese medicine preparation and method for making for the treatment of postcerebral injury syndrome
Technical field
The invention discloses one and treat postcerebral injury syndrome oral traditional Chinese medicine preparation, especially relate to a kind of oral traditional Chinese medicine preparation for the treatment of postcerebral injury syndrome and preparation method thereof, the invention belongs to traditional Chinese medicine field.
Background technology
Cerebral trauma refers to cause due to foreign object, the macroscopic wound in brains portion, generally can cause serious consequence.Cerebral trauma often causes permanent disfunction in various degree.This depends primarily on infringement is in certain specific region (focal) of cerebral tissue or the infringement of popularity (dispersivity).The cerebral lesion of zones of different can cause different symptoms, and focal symptom comprises the symptoms such as motion, sensation, speech, vision, auditory abnormality.And DD often affects memory, sleeps or causes confusion and stupor.The cause of disease: unexpected head accelerated motion, equally with head of fiercelying attack causes brain tissue impairment.The irremovable hard object of head fast ram or retarded motion suddenly are also common cerebral trauma reasons.The side be impacted or rightabout cerebral tissue and hard and the skull of projection collides time very easily sustain damage.Acceleration-deceleration damage is sometimes also referred to as offside blast injury.
Clinical manifestation 1. cerebral concussion syndrome: occur of short duration loss of consciousness after cerebral concussion, recovers in general 30 minutes.After waking up, patient is to a moment before injured scene and wound, situation can not be recalled.Patient can have headache, vomiting, dizzy, irritability, and emotional lability is self-doubt, distractibility, and vegetative nerve symptom is as palor, and cold sweat, blood pressure drops, pulse is slow, hypopnea etc.2. the caused stupor of cerebral trauma: the stupor that duration differs can occur craniocerebral injury, stupor is to recovering clear-headed process, and can there be lethargy centre, muddy, delirium etc.Heavily in undulatory property time light during disturbance of consciousness.3. delirium caused by cerebral trauma: delirium is generally by go into a coma or lethargy transfers.Occupational characteristic before the behavior reflection of some patient when delirium is sick.Many patients show opposing, noisy, uncooperative, and other are more aggressive.Can have phobic photis, serious patient can have confusion excited, the behavior of even strong impulse sexual violence.Delirium can replace by illiteracy other disturbance of consciousnesss such as XML-Feed-JS-Feed and oneiroid state.4. amnestic syndrome caused by cerebral trauma: its most outstanding feature forgets fabricating on basis, the normal irritability of patient.Its Duration Ratio alcoholic-toxic amnestic syndrome is short.5. subdural hematoma caused by cerebral trauma: can occur very soon after injured, most headache and drowsiness.Excited with delirious mobility once in a while, about half patient has papilloedema.The feature of chronic subdural hematoma is drowsiness, blunt, hypomnesis, and generalized dementia symptom appears in severe patient, and some patients's cerebrospinal pressure slightly raises, and protein quantification increases, and outward appearance is in yellow.
Authorization Notice No. CN 102631579 B(application number 201210113893.1) patent discloses a kind of oral traditional Chinese medicine preparation for the treatment of postcerebral injury syndrome, it is characterized in that adopting the raw material of Chinese medicine of following weight parts to make: the Radix Astragali 10 ± 2, Radix Panacis Quinquefolii 10 ± 2, Radix Angelicae Sinensis 10 ± 2, Fructus Lycii 10 ± 2, Radix Dipsaci 10 ± 2, Rhizoma Chuanxiong 10 ± 2, Radix Paeoniae Rubra 10 ± 2, Semen Persicae 10 ± 2, Poria 10 ± 2, Pericarpium Citri Reticulatae 10 ± 2, Rhizoma Chuanxiong 10 ± 2, Concretio Silicea Bambusae 10 ± 2, Rhizoma Acori Graminei 10 ± 2, Rhizoma Gastrodiae 10 ± 2, Ramulus Uncariae Cum Uncis 10 ± 2, Semen Ziziphi Spinosae 10 ± 2, Succinum powder 10 ± 2, Radix Glycyrrhizae Preparata 6 ± 1.2.Authorization Notice No. CN 103386080 B(application number 201310286335.X) the drug oral Chinese medicine preparation that patent discloses a kind of clinical care postcerebrotraumatic syndrome, it is prepared by the raw material of following weight proportioning and obtains: Radix Rehmanniae Preparata 27 parts, Radix Angelicae Sinensis 25 parts, Radix Paeoniae Rubra 25 parts, Rhizoma Curcumae 22 parts, Radix Notoginseng 22 parts, Semen Raphani 20 parts, Herba Patriniae 20 parts, Rhizoma Chuanxiong 18 parts, Herba Lycopi 18 parts, the Cortex Eucommiae 17 parts, Flos Campsis 15 parts, Arillus Longan 15 parts, Folium Perillae 15 parts, Rhizoma Dioscoreae 15 parts, the Radix Aucklandiae 13 parts, 12 parts, Fructus Mori, 12 parts, Poria, 12 parts, Radix Glycyrrhizae, Radix Saposhnikoviae 10 parts, Radix Trichosanthis 10 parts, Rhizoma Cyperi 10 parts, Cortex Albiziae 10 parts, Rhizoma Chuanxiong 8 parts, Semen Juglandis 8 parts, Herba Scutellariae Barbatae 7 parts, 5 parts, Semen Armeniacae Amarum, Cortex Phellodendri 5 parts, Spica Prunellae 3 parts, Fructus Lycii 3 parts.
As can be seen here, Chinese medicine occupies very important status in treatment postcerebral injury syndrome, but preparation method is complicated, and great majority are all decoctions, and one is be inconvenient to carry, and two is that pure Chinese medicinal preparation damages to some extent to health unavoidably.
Summary of the invention
Along with the development of Chinese Chinese medicine, on Cure and control postcerebral injury syndrome, people gradually appreciate Chinese medicine and have no side effect at postcerebral injury syndrome disease therapeutic process, patient bears painful little, the advantage that cost is saved relatively, for the present situation of existing western medical treatment postcerebral injury syndrome, an object of the present invention is to provide a kind of oral traditional Chinese medicine preparation for the treatment of postcerebral injury syndrome, there is feature easy to operate, evident in efficacy, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Treat an oral traditional Chinese medicine preparation for postcerebral injury syndrome, take off the primary raw material stating weight proportion and be prepared from: Rhizoma Chuanxiong 3-9 part, Radix Schefflerae Delavayi 5-9 part, Radix Notoginseng 1-5 part, Radix Dipsaci 2-6 part, Ganoderma 1-3 part, Rhizoma Acori Graminei 3-7 part, Flos Carthami 4-6 part, Radix Platycodonis 2-4 part, Herba Centellae 5-15 part, Arillus Longan 5-9 part, Bulbus Lilii 3-6 part, Fructus Mori 1-3 part, Semen Sesami Nigrum 6-10 part, Semen Glycines 10-20 part, Semen Juglandis 10-15 part.
Treat an oral traditional Chinese medicine preparation for postcerebral injury syndrome, preferred scheme, take off the primary raw material stating weight proportion and be prepared from: Rhizoma Chuanxiong 5-7 part, Radix Schefflerae Delavayi 6-8 part, Radix Notoginseng 2-4 part, Radix Dipsaci 3-5 part, Ganoderma 1.5-2.5 part, Rhizoma Acori Graminei 4-6 part, Flos Carthami 4.5-5.5 part, Radix Platycodonis 2.5-3.5 part, Herba Centellae 8-13 part, Arillus Longan 6-8 part, Bulbus Lilii 4-5 part, Fructus Mori 1.5-2.5 part, Semen Sesami Nigrum 7-9 part, Semen Glycines 13-18 part, Semen Juglandis 11-14 part.
Treat an oral traditional Chinese medicine preparation for postcerebral injury syndrome, better preferred scheme, take off the primary raw material stating weight proportion and be prepared from: Rhizoma Chuanxiong 6 parts, Radix Schefflerae Delavayi 7 parts, Radix Notoginseng 3 parts, Radix Dipsaci 4 parts, Ganoderma 2 parts, Rhizoma Acori Graminei 5 parts, 5 parts, Flos Carthami, Radix Platycodonis 3 parts, Herba Centellae 10 parts, Arillus Longan 7 parts, Bulbus Lilii 4.5 parts, Fructus Mori 2 parts, Semen Sesami Nigrum 8 parts, Semen Glycines 15 parts, Semen Juglandis 12.5 parts.
Another object of the present invention is just to provide the preparation method of above-mentioned treatment postcerebral injury syndrome.
Treat a preparation method for the oral traditional Chinese medicine preparation of postcerebral injury syndrome, step is as follows:
1. by Semen Juglandis and Semen Sesami Nigrum mixing, be placed in the hot pot that dryouies, stir-fry 5-10 minute repeatedly, grinds to form smalls, crosses 100-140 mesh sieve stand-by;
2. be placed in transparent glass container by Semen Glycines, add Semen Glycines weight 2-4 warm water doubly, 2-6 hour is soaked in sealing, and taking-up drains away the water, and be placed on clean iron plate, little fire dries 10-20 minute slowly, glues and removes onal, grind to form smalls, crosses 80-120 mesh sieve stand-by;
3. fresh Arillus Longan and fresh Bulbus Lilii and Fructus Mori are mixed, become thick liquid with mortar grinder, cross 160-200 order drainage screen, filtering residue is stand-by;
4. Rhizoma Chuanxiong, Radix Schefflerae Delavayi, Radix Notoginseng, Radix Dipsaci, Ganoderma, Rhizoma Acori Graminei, Flos Carthami, Radix Platycodonis and Herba Centellae are cleaned, drain away the water, smash to pieces, fry 2-6 minute, grinding to form smalls, to cross 80-120 mesh sieve stand-by;
5. by step 1.-4. gains mixing, add mixed material medicine weight 1.5-2.5 Mel doubly, stir into thick paste, adding clear water, is decocting and be stirred to boiling with chopsticks, after seething with excitement 3-6 minute, truce, cools, bottles and obtain oral traditional Chinese medicine preparation.
The preparation method of above-mentioned oral traditional Chinese medicine preparation, 1. step stir-fries 6-9 minute repeatedly, grinds to form smalls, crosses 110-130 mesh sieve (preferred, repeatedly to stir-fry 7 minutes, grind to form smalls, cross 120 mesh sieves stand-by).
The preparation method of above-mentioned oral traditional Chinese medicine preparation, 2. step adds Semen Glycines weight 2.5-3.5 warm water doubly, and sealing is soaked 3-5 hour (preferred, to add the warm water of Semen Glycines weight 3 times, sealing immersion 4 hours).
The preparation method of above-mentioned oral traditional Chinese medicine preparation, step 2. little fire dries 13-18 minute slowly, glues and removes onal, grind to form smalls, crosses 90-110 mesh sieve (preferred, little fire dries 15 minutes slowly, glues and removes onal, grind to form smalls, crosses 100 mesh sieves).
The preparation method of above-mentioned oral traditional Chinese medicine preparation, step 3. thick liquid crosses 170-190 order drainage screen (preferred thick liquid crosses 180 order drainage screens).
The preparation method of above-mentioned oral traditional Chinese medicine preparation, 4. step is smashed to pieces, fries 3-5 minute, grinds to form smalls and crosses 90-110 mesh sieve (preferred, to smash to pieces, fry 4 minutes, grind to form smalls and cross 100 mesh sieves).
The preparation method of above-mentioned oral traditional Chinese medicine preparation, 5. step adds mixed material medicine weight 1.8-2.3 Mel doubly (preferred, to add the Mel of mixed material medicine weight 2 times).
This oral traditional Chinese medicine preparation is to postcerebral injury syndrome Be very effective, good mitigation is had to the headache caused by postcerebral injury syndrome, insomnia, dreaminess, tinnitus, cardiopalmus, hyperhidrosis and the symptom such as absent minded, the local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
The pharmacological effect of each crude drug is respectively:
Rhizoma Chuanxiong: base is former: be the rhizome of Umbelliferae Rhizoma Ligustici platymiscium Rhizoma Chuanxiong.Composition: rhizome is containing multiple lactone: ligustrazine, loline or perlolyrine, Rhizoma Ligustici lactone, Rhizoma Chuanxiong naphthalene furan lactone, butylphthalide, two phthalide-type, cnidiumm lactone etc.The property of medicine: pungent, temperature.Return liver, gallbladder pericardium channel.Function cures mainly: blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping.Cure mainly menoxenia, amenorrhea dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal, lump in the abdomen lump, pain in chest and hypochondrium, has a headache dizzy, anemofrigid-damp arthralgia, traumatic injury, ulcer sores.
Radix Schefflerae Delavayi: be the root of Araliaceae Schefflera plant Schettlera delavayi and root bark or branch.The property of medicine: micro-hardship, puckery, flat.Function cures mainly: dispelling, collateral-activating, strengthening the tendons and bones, promoting flow of QI and blood.Cure mainly rheumatic arthralgia, soreness of waist and knee joint, treating swelling and pain by traumatic injury, breast side of body abdominal distention.
Radix Notoginseng: return liver, stomach warp.Effect dissipating blood stasis stops blooding, subduing swelling and relieving pain.Cure mainly for spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.
Radix Dipsaci: invigorating the liver and kidney, reuniting the fractured tendons and bones, blood circulation regulating.Control aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia, seminal emission, traumatic injury, incised wound, anal fistula, carbuncle skin ulcer swells.1. " herbal classic ": main typhoid fever, tonifying for the deficiency, incised wound, carbuncle and ulcer, folding falls, reuniting the fractured tendons and bones, and married woman's breast is difficult, takes physical strength profiting for a long time.2. " not Lu ": main metrorrhagia leaks blood, incised wound blood internal hemorrhage due to trauma, pain relieving, granulation promoting meat, wrist be hindered, stagnant blood, lumbago, joint emergency.
Ganoderma: nature and flavor: warm in nature, lightly seasoned.Character: gas is special, mildly bitter flavor is puckery.Malaise, insomnia, palpitation with fear.This product sweet in the mouth is put down, and enters heart channel, can reinforcing the heart blood, the beneficial motive, tranquilizing mind, therefore availablely controls the disease such as malaise caused by insufficiency of vital energy and blood, lack of preservation of spirit, insomnia, palpitation with fear, dreaminess, forgetful, the tired Mental fatigue of body, lack of appetite.
Rhizoma Acori Graminei: another name Rhizoma Anemones Altaicae, water Rhizoma Acori Graminei, powder Chang, mountain Rhizoma Acori Graminei, small stream Chang, stone Scolopendra, wild leek.Flavor efficacy: pungent, flat or tepor.Enter the heart, liver, spleen channel.Fresh goods strong flavor, pungent loose power more wins than dry product, therefore the good merchantable brand for declaring gas sensible.This product had both been longer than removing dampness by means of aromatics, activating spleen and strengthening stomach, was used for the treatment of cloudy stagnant middle Jiao of turbid damp, vexed swollen, all diseases of anorexia of functional activity of QI being not smooth, breast gastral cavity; And again can fragrant magnificent expectorant turbid, resuscitation inducing and mind tranquilizing, is used for the treatment of the mind that turbid damp hoodwinks clearly caused by key dazed and confused, the disease of white and greasy fur; And arrogate to oneself the unconsciousness controlled expectorant heat and fall caused by stagnant pericardium, the diseases such as tic.
Flos Carthami: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, contributes to controlling amenorrhea, dysmenorrhea, lochia, obstruction of qi in the chest and cardialgia, the stagnant stomachache of the stasis of blood, the twinge of the breast side of body, traumatic injury, skin infection swells and ache curative effect.Have blood circulation promoting and blood stasis dispelling, wet dissipation goes the effect swollen, and avoids anemia of pregnant woman to use, otherwise can cause miscarriage.
Radix Platycodonis: lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Herba Centellae: be dry herb or the whole herb with root of dicotyledon Umbelliferae Herba Centellae.Composition: containing the Triterpenoid of multiple α-balsam alcohol type, wherein have asiaticoside, thankuniside, isothankuniside, asiaticoside, Brahmoside, broken hot rice glycosides and Brahmic acid etc., and madasiatic acid.The property of medicine: bitter, acrid, cold.Return liver,spleen,kidney warp.Function cures mainly: heat-clearing and toxic substances removing, inducing diuresis and reducing edema.Be the long-lived medicine of Asians, can refresh oneself by beneficial brain.Research shows to have nourishing, antiinflammatory, healing of wound, diuresis relieving constipation and calm effect.Also effective in cure to leprosy, ulcer, there is activation to blood purification and immunity, because it can stimulate the replacement of deep skin cell.It is neural nourishing agent, can improve memory, alleviate mental fatigue; Also can blood pressure lowering, treatment hepatopathy etc.
Arillus Longan: reinforcing the heart spleen, replenishing QI and blood, strengthening the spleen and stomach, supports muscle.Worry impairing spleen, dizzy, insomnia, severe palpitation, emptyly wins, and after being ill or puerperal asthenia, and to lose blood disease due to insufficiency of the spleen caused hematochezia.Modem medical practices proves, it also has effect of beauty treatment, life lengthening.
Bulbus Lilii: sweet; Micro-hardship; Be slightly cold, Gui Jing: the heart; Lung meridian, function cures mainly: nourishing YIN and moistening the lung; Clearing away heart-fire for tranquillization.Main deficiency of YIN chronic cough; Sputum mixed with blood; The calentura later stage; Waste heat is clear, or the unsuccessful caused fidgets due to deficiency palpitation with fear of feelings will, insomnia and dreamful sleep, absentminded; Carbuncle; Eczema.
Fructus Mori: be the dry fruit ear of Moraceae Mulberry plant Mulberry.Composition: fruit ear is containing vitamin B1, B2 and carotene; The fatty acid of its lipid is mainly linoleic acid, oleic acid, palmitic acid, stearic acid, and there still have to be sad on a small quantity, n-nonanoic acid, capric acid etc.The property of medicine: sweet, sour, cold.Return sweet, kidney channel.Function cures mainly: nourishing YIN and benefiting blood, promotes the production of body fluid, intestine moistening.Cure mainly having a dizzy spell of deficiency of the liver and kindey and blood deficiency damage of essence, tinnitus, early whitening of beard and hair, insomnia, quenches one's thirst, the soreness of waist, dryness of the intestine constipation, tinea alba.
Semen Sesami Nigrum: Semen Sesami honey cake: the effect having stomach invigorating, protect the liver, promote red blood cell growth.Semen Sesami Nigrum mulberry is stuck with paste: this sticks with paste invigorating the liver and kidney, moistening five ZANG-organs, wind-damp dispelling, clear asthenic fire, informal dress can cure the disease after the diseases such as weakness with emaciation, early whitening of beard and hair, wind syndrome caused by deficiency be dizzy.
Semen Glycines: soybean fat also has very high nutritive value, containing a lot of unsaturated fatty acid in this fat, easily digested.And soybean fat can stop the absorption of cholesterol, so Semen sojae atricolor is for arteriosclerotic, it is a kind of desirable nutriment.Dietary fiber in bean dregs has very important effect to the good digestion of promotion and excretion solid waste.Supplementary fibre element in appropriate amount, can make the food in intestinal increase deliquescing, promote intestinal peristalsis promoting, thus accelerate defecation speed, prevent the risk of constipation and reduction intestinal cancer.Meanwhile, dietary fiber has and significantly reduces plasma cholesterol, regulates the function such as gastrointestinal function and insulin level.Soybean meal is the residual dregs of rice side-product after Semen sojae atricolor low temperature (40-60 DEG C) restricted-access media oils and fats, in coarse powder shape.Because not being subject to temperature, the antitrypsin of Semen sojae atricolor, urase, hemagglutinin, Saponin, goiter incitant can not be destroyed.Soybean cake dregs uses the vegetable protein raw material the widest, consumption is maximum.
Semen Juglandis: the strong body of tonify deficiency, provides nutrition: prove through zoopery, containing the mixing-in fat diet of Oleum Juglandis, can make body weight increase, and serum albumin increases, and blood cholesterol levels raises comparatively slow, therefore Semen Juglandis is the tonic product of rare a kind of higher fatty acid property material.Brain-strengthening is anti-old: Semen Juglandis contains more protein and the required unsaturated fatty acid of human nutrition, and these compositions are all the important substance of cerebral tissue cellular metabolism, can nursing brain cells, cerebral function improvement.Purify the blood, reduce cholesterol: Semen Juglandis can reduce the absorption of intestinal to cholesterol.And solubilized cholesterol, " the dirt impurity " got rid of in blood vessel wall makes blood purification, thus provides better fresh blood for human body.So Semen Juglandis prevents arteriosclerosis, reduce the effect of cholesterol.In addition, Semen Juglandis also can be used for treating non-insulin-dependent diabetes mellitus.
Oral traditional Chinese medicine preparation of the present invention debates the principle of disease treatment based on Chinese medicine, and treatment is more comprehensive, and lasting medicine, has fabulous therapeutical effect to postcerebral injury syndrome, has fabulous opsonic action for the health thin and weak because of chronic pain.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1treat an oral traditional Chinese medicine preparation for postcerebral injury syndrome, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Rhizoma Chuanxiong 3 parts, Radix Schefflerae Delavayi 5 parts, Radix Notoginseng 1 part, Radix Dipsaci 2 parts, Ganoderma 1 part, Rhizoma Acori Graminei 3 parts, 4 parts, Flos Carthami, Radix Platycodonis 2 parts, Herba Centellae 5 parts, Arillus Longan 5 parts, Bulbus Lilii 3 parts, Fructus Mori 1 part, Semen Sesami Nigrum 6 parts, Semen Glycines 10 parts, Semen Juglandis 10 parts.
Treat an oral traditional Chinese medicine preparation for postcerebral injury syndrome, preparation process is as follows:
1. by Semen Juglandis and Semen Sesami Nigrum mixing, be placed in the hot pot that dryouies, repeatedly stir-fry 5 minutes, grind to form smalls, cross 100 mesh sieves stand-by;
2. be placed in transparent glass container by Semen Glycines, add the warm water of Semen Glycines weight 2 times, sealing immersion 2 hours, taking-up drains away the water, and be placed on clean iron plate, little fire dries 10 minutes slowly, glues and removes onal, grind to form smalls, crosses 80 mesh sieves stand-by;
3. fresh Arillus Longan and fresh Bulbus Lilii and Fructus Mori are mixed, become thick liquid with mortar grinder, cross 160 order drainage screens, filtering residue is stand-by;
4. Rhizoma Chuanxiong, Radix Schefflerae Delavayi, Radix Notoginseng, Radix Dipsaci, Ganoderma, Rhizoma Acori Graminei, Flos Carthami, Radix Platycodonis and Herba Centellae are cleaned, drain away the water, smash to pieces, fry 2 minutes, grinding to form smalls, to cross 80 mesh sieves stand-by;
5. by step 1.-4. gains mixing, add the Mel of mixed material medicine weight 1.5 times, stir into thick paste with chopsticks, adding clear water, decocting and be stirred to boiling, until boiling after 3 minutes, truce, cool, bottle and obtain oral traditional Chinese medicine preparation.
model case one:king XX, female, 48 years old, Jinan City, Shandong Province personage, the employee of certain company.Symptom: patient's 3 years protocerebral region trauma history, leave over paroxysmal headaches, anxiety is then had a headache when anything crops up, private prosecution dare not too much ponder a problem, nearly Headache attacks half a year gradually frequency, conscious cardiopalmus is slept few, dreaminess, irritable, spiritlessness and weakness, indigestion and loss of appetite lack of appetite, Shi Zihan, menstruation irregularis, in the time of nearest half a year, above-mentioned malaise symptoms is even more serious, intermenstrual period extends, the few color of amount is light, recent oral ibuprofen pain relieving, shallow complexion, pale tongue with thin fur is white, deep-thready pulse and weak, there is hypomnesis in what is more important, expression is stayed blunt, the symptom of delay of response and walking shakiness, hospital diagnosis is gone to be postcerebral injury syndrome, because this disease needs conditioning, gained oral traditional Chinese medicine preparation of the present invention is taken in suggestion.
Journey is taken and is taken embodiment 1 gained oral traditional Chinese medicine preparation, gets 10ml, one day 3 times at every turn, take half an hour after meal, within 5 days, be a course for the treatment of, take a course for the treatment of, symptom takes a turn for the better, headache degree, seizure frequency alleviate, continue to take to two courses for the treatment of, all diseases disappear, analgesic of stopping using completely, recovery from illness, follows up a case by regular visits to half a year without recurrence.
embodiment 2treat an oral traditional Chinese medicine preparation for postcerebral injury syndrome, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Rhizoma Chuanxiong 9 parts, Radix Schefflerae Delavayi 9 parts, Radix Notoginseng 5 parts, Radix Dipsaci 6 parts, Ganoderma 3 parts, Rhizoma Acori Graminei 7 parts, 6 parts, Flos Carthami, Radix Platycodonis 4 parts, Herba Centellae 15 parts, Arillus Longan 9 parts, Bulbus Lilii 6 parts, Fructus Mori 3 parts, Semen Sesami Nigrum 10 parts, Semen Glycines 20 parts, Semen Juglandis 15 parts.
Treat an oral traditional Chinese medicine preparation for postcerebral injury syndrome, preparation process is as follows:
1. by Semen Juglandis and Semen Sesami Nigrum mixing, be placed in the hot pot that dryouies, repeatedly stir-fry 10 minutes, grind to form smalls, cross 140 mesh sieves stand-by;
2. be placed in transparent glass container by Semen Glycines, add the warm water of Semen Glycines weight 4 times, sealing immersion 6 hours, taking-up drains away the water, and be placed on clean iron plate, little fire dries 20 minutes slowly, glues and removes onal, grind to form smalls, crosses 120 mesh sieves stand-by;
3. fresh Arillus Longan and fresh Bulbus Lilii and Fructus Mori are mixed, become thick liquid with mortar grinder, cross 200 order drainage screens, filtering residue is stand-by;
4. Rhizoma Chuanxiong, Radix Schefflerae Delavayi, Radix Notoginseng, Radix Dipsaci, Ganoderma, Rhizoma Acori Graminei, Flos Carthami, Radix Platycodonis and Herba Centellae are cleaned, drain away the water, smash to pieces, fry 6 minutes, grinding to form smalls, to cross 120 mesh sieves stand-by;
5. by step 1.-4. gains mixing, add the Mel of mixed material medicine weight 2.5 times, stir into thick paste with chopsticks, adding clear water, decocting and be stirred to boiling, until boiling after 6 minutes, truce, cool, bottle and obtain oral traditional Chinese medicine preparation.
embodiment 3treat an oral traditional Chinese medicine preparation for postcerebral injury syndrome, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Rhizoma Chuanxiong 5 parts, Radix Schefflerae Delavayi 6 parts, Radix Notoginseng 2 parts, Radix Dipsaci 3 parts, Ganoderma 1.5 parts, Rhizoma Acori Graminei 4 parts, 4.5 parts, Flos Carthami, Radix Platycodonis 2.5 parts, Herba Centellae 8 parts, Arillus Longan 6 parts, Bulbus Lilii 4 parts, Fructus Mori 1.5 parts, Semen Sesami Nigrum 7 parts, Semen Glycines 13 parts, Semen Juglandis 11 parts.
Treat an oral traditional Chinese medicine preparation for postcerebral injury syndrome, preparation process is as follows:
1. by Semen Juglandis and Semen Sesami Nigrum mixing, be placed in the hot pot that dryouies, stir-fry 5-10 minute repeatedly, grinds to form smalls, crosses 110 mesh sieves stand-by;
2. be placed in transparent glass container by Semen Glycines, add the warm water of Semen Glycines weight 2.5, sealing immersion 3 hours, taking-up drains away the water, and be placed on clean iron plate, little fire dries 13 minutes slowly, glues and removes onal, grind to form smalls, crosses 90 mesh sieves stand-by;
3. fresh Arillus Longan and fresh Bulbus Lilii and Fructus Mori are mixed, become thick liquid with mortar grinder, cross 170 order drainage screens, filtering residue is stand-by;
4. Rhizoma Chuanxiong, Radix Schefflerae Delavayi, Radix Notoginseng, Radix Dipsaci, Ganoderma, Rhizoma Acori Graminei, Flos Carthami, Radix Platycodonis and Herba Centellae are cleaned, drain away the water, smash to pieces, fry 3 minutes, grinding to form smalls, to cross 90 mesh sieves stand-by;
5. by step 1.-4. gains mixing, add the Mel of mixed material medicine weight 1.8 times, stir into thick paste with chopsticks, adding clear water, decocting and be stirred to boiling, until boiling after 4 minutes, truce, cool, bottle and obtain oral traditional Chinese medicine preparation.
embodiment 4treat an oral traditional Chinese medicine preparation for postcerebral injury syndrome, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Rhizoma Chuanxiong 7 parts, Radix Schefflerae Delavayi 8 parts, Radix Notoginseng 4 parts, Radix Dipsaci 5 parts, Ganoderma 2.5 parts, Rhizoma Acori Graminei 6 parts, 5.5 parts, Flos Carthami, Radix Platycodonis 3.5 parts, Herba Centellae 13 parts, Arillus Longan 8 parts, Bulbus Lilii 5 parts, Fructus Mori 2.5 parts, Semen Sesami Nigrum 9 parts, Semen Glycines 18 parts, Semen Juglandis 14 parts.
Treat an oral traditional Chinese medicine preparation for postcerebral injury syndrome, preparation process is as follows:
1. by Semen Juglandis and Semen Sesami Nigrum mixing, be placed in the hot pot that dryouies, repeatedly stir-fry 9 minutes, grind to form smalls, cross 130 mesh sieves stand-by;
2. be placed in transparent glass container by Semen Glycines, add the warm water of Semen Glycines weight 3.5 times, sealing immersion 5 hours, taking-up drains away the water, and be placed on clean iron plate, little fire dries 18 minutes slowly, glues and removes onal, grind to form smalls, crosses 110 mesh sieves stand-by;
3. fresh Arillus Longan and fresh Bulbus Lilii and Fructus Mori are mixed, become thick liquid with mortar grinder, cross 190 order drainage screens, filtering residue is stand-by;
4. Rhizoma Chuanxiong, Radix Schefflerae Delavayi, Radix Notoginseng, Radix Dipsaci, Ganoderma, Rhizoma Acori Graminei, Flos Carthami, Radix Platycodonis and Herba Centellae are cleaned, drain away the water, smash to pieces, fry 5 minutes, grinding to form smalls, to cross 110 mesh sieves stand-by;
5. by step 1.-4. gains mixing, add the Mel of mixed material medicine weight 2.3 times, stir into thick paste with chopsticks, adding clear water, decocting and be stirred to boiling, until boiling after 5 minutes, truce, cool, bottle and obtain oral traditional Chinese medicine preparation.
model case two:zou xx, man, 68 years old, people from Jiyang County, Jinan City, Shandong Province.Symptom: in December, 2009, occur headache, dizzy, feel sick, hypomnesis 2 months.Patient before 1 year by motorcycle time fall down, cerebral CT shows fracture of skull, depressed fracture reset, leave over headache after short term therapy.Patient often has head distending pain, isolate pain or jumping pain, and head likes cold aversion to heat, and duration of seizure is indefinite, can because of insomnia, tired, emotion is not good enough, the smooth or not extraneous clamour of work and aggravating.Dizzy, feel sick, feel dizzy, thinking be clear not.Patient is also often in a bad mood instability, easily tired, insomnia, absent minded, hypomnesis, and light red tongue, tongue is white, and deep and weak pulse is unable, and more so, expression is painful, but conscious for two chi pulse.CT checks Non Apparent Abnormality.Diagnosis: go hospital diagnosis to be postcerebral injury syndrome.
Take and take embodiment 4 gained oral traditional Chinese medicine preparation, getting 10ml at every turn, one day 3 times, take half an hour after meal, 5 days is a course for the treatment of, and take a course for the treatment of, rear headache and dizzy greatly takes a turn for the better, continuous clothes, and after two courses for the treatment of, all diseases disappear.Follow up a case by regular visits to half a year, no headache, dizzy phenomenon, spirit sleep, memory all take a turn for the better.
embodiment 5treat an oral traditional Chinese medicine preparation for postcerebral injury syndrome, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Rhizoma Chuanxiong 6 parts, Radix Schefflerae Delavayi 7 parts, Radix Notoginseng 3 parts, Radix Dipsaci 4 parts, Ganoderma 2 parts, Rhizoma Acori Graminei 5 parts, 5 parts, Flos Carthami, Radix Platycodonis 3 parts, Herba Centellae 10 parts, Arillus Longan 7 parts, Bulbus Lilii 4.5 parts, Fructus Mori 2 parts, Semen Sesami Nigrum 8 parts, Semen Glycines 15 parts, Semen Juglandis 12.5 parts.
Treat an oral traditional Chinese medicine preparation for postcerebral injury syndrome, preparation process is as follows:
1. by Semen Juglandis and Semen Sesami Nigrum mixing, be placed in the hot pot that dryouies, repeatedly stir-fry 7 minutes, grind to form smalls, cross 120 mesh sieves stand-by;
2. be placed in transparent glass container by Semen Glycines, add the warm water of Semen Glycines weight 3 times, sealing immersion 4 hours, taking-up drains away the water, and be placed on clean iron plate, little fire dries 15 minutes slowly, glues and removes onal, grind to form smalls, crosses 100 mesh sieves stand-by;
3. fresh Arillus Longan and fresh Bulbus Lilii and Fructus Mori are mixed, become thick liquid with mortar grinder, cross 180 order drainage screens, filtering residue is stand-by;
4. Rhizoma Chuanxiong, Radix Schefflerae Delavayi, Radix Notoginseng, Radix Dipsaci, Ganoderma, Rhizoma Acori Graminei, Flos Carthami, Radix Platycodonis and Herba Centellae are cleaned, drain away the water, smash to pieces, fry 4 minutes, grinding to form smalls, to cross 100 mesh sieves stand-by;
5. by step 1.-4. gains mixing, add the Mel of mixed material medicine weight 2 times, stir into thick paste with chopsticks, be contained in and add clear water, decoct and be stirred to boiling, until boiling after 4 minutes, truce, cool, bottle and obtain oral traditional Chinese medicine preparation.
experimental example:1, selection of clinical: in order to verify the effect of oral traditional Chinese medicine preparation of the present invention, we have extracted 400 patients and have carried out the experiment of medicine, are equally divided into two groups, experimental group and matched group.
2, inclusion criteria: through being diagnosed as the patient once suffering from postcerebral injury syndrome, disease 1-5 in age, there is postcerebral injury syndrome clinical sequelae one or more (with degradation subjective symptoms under headache, insomnia, dreaminess, tinnitus, cardiopalmus, hyperhidrosis, absent minded, nauseating and appetite, but without definite nervous system positive sign, head CT, MRI check also discovery without exception).
3, instructions of taking: at every turn get 10ml, one day 3 times, takes after meal half an hour, within 5 days, is a course for the treatment of.
4, curative effect situation criterion: 1, effective: after drug administration, malaise symptoms alleviates or partial disappearance; 2, invalid: after drug administration, malaise symptoms is unchanged.We conducted the experiment (embodiment 5) of medicine, and accurately statistics and mathematical analysis have been carried out to data.
Specific experiment result is as following table:
Table 1:
Table 2:
group drug categories case load postcerebral injury syndrome patient oneself status evaluation
matched group western medical treatment postcerebral injury syndrome method 200 people the people of 60% thinks that employing western medical treatment, health are subject to burden large, and spirit is all very painful with health.
oral traditional Chinese medicine preparation of the present invention oral traditional Chinese medicine preparation of the present invention 200 people the people of 97% thinks with the present invention's treatment, effectively can alleviate every misery that postcerebral injury syndrome brings.
Prove through clinical trial, take oral traditional Chinese medicine preparation of the present invention compared with the means of western medical treatment postcerebral injury syndrome, control recurrence rate after healing low, treatment means is more comprehensive thoroughly, have no side effect during taking, prove through clinical trial, Chinese drugs agentia effective percentage of the present invention is 99%, has good therapeutical effect to postcerebral injury syndrome.

Claims (10)

1. treat an oral traditional Chinese medicine preparation for postcerebral injury syndrome, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Rhizoma Chuanxiong 3-9 part, Radix Schefflerae Delavayi 5-9 part, Radix Notoginseng 1-5 part, Radix Dipsaci 2-6 part, Ganoderma 1-3 part, Rhizoma Acori Graminei 3-7 part, Flos Carthami 4-6 part, Radix Platycodonis 2-4 part, Herba Centellae 5-15 part, Arillus Longan 5-9 part, Bulbus Lilii 3-6 part, Fructus Mori 1-3 part, Semen Sesami Nigrum 6-10 part, Semen Glycines 10-20 part, Semen Juglandis 10-15 part.
2. treat the oral traditional Chinese medicine preparation of postcerebral injury syndrome according to claim 1, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Rhizoma Chuanxiong 5-7 part, Radix Schefflerae Delavayi 6-8 part, Radix Notoginseng 2-4 part, Radix Dipsaci 3-5 part, Ganoderma 1.5-2.5 part, Rhizoma Acori Graminei 4-6 part, Flos Carthami 4.5-5.5 part, Radix Platycodonis 2.5-3.5 part, Herba Centellae 8-13 part, Arillus Longan 6-8 part, Bulbus Lilii 4-5 part, Fructus Mori 1.5-2.5 part, Semen Sesami Nigrum 7-9 part, Semen Glycines 13-18 part, Semen Juglandis 11-14 part.
3. treat the oral traditional Chinese medicine preparation of postcerebral injury syndrome according to claim 1, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Rhizoma Chuanxiong 6 parts, Radix Schefflerae Delavayi 7 parts, Radix Notoginseng 3 parts, Radix Dipsaci 4 parts, Ganoderma 2 parts, Rhizoma Acori Graminei 5 parts, 5 parts, Flos Carthami, Radix Platycodonis 3 parts, Herba Centellae 10 parts, Arillus Longan 7 parts, Bulbus Lilii 4.5 parts, Fructus Mori 2 parts, Semen Sesami Nigrum 8 parts, Semen Glycines 15 parts, Semen Juglandis 12.5 parts.
4. according to any one of claim 1-3, treat the preparation method of the oral traditional Chinese medicine preparation of postcerebral injury syndrome, it is characterized in that: step is as follows:
1. by Semen Juglandis and Semen Sesami Nigrum mixing, be placed in the hot pot that dryouies, stir-fry 5-10 minute repeatedly, grinds to form smalls, crosses 100-140 mesh sieve stand-by;
2. be placed in transparent glass container by Semen Glycines, add Semen Glycines weight 2-4 warm water doubly, 2-6 hour is soaked in sealing, and taking-up drains away the water, and be placed on clean iron plate, little fire dries 10-20 minute slowly, glues and removes onal, grind to form smalls, crosses 80-120 mesh sieve stand-by;
3. fresh Arillus Longan and fresh Bulbus Lilii and Fructus Mori are mixed, become thick liquid with mortar grinder, cross 160-200 order drainage screen, filtering residue is stand-by;
4. Rhizoma Chuanxiong, Radix Schefflerae Delavayi, Radix Notoginseng, Radix Dipsaci, Ganoderma, Rhizoma Acori Graminei, Flos Carthami, Radix Platycodonis and Herba Centellae are cleaned, drain away the water, smash to pieces, fry 2-6 minute, grinding to form smalls, to cross 80-120 mesh sieve stand-by;
5. by step 1.-4. gains mixing, add mixed material medicine weight 1.5-2.5 Mel doubly, stir into thick paste, adding clear water, is decocting and be stirred to boiling with chopsticks, after seething with excitement 3-6 minute, truce, cools, bottles and obtain oral traditional Chinese medicine preparation.
5. the preparation method of oral traditional Chinese medicine preparation according to claim 4, is characterized in that: 1. step stir-fries 6-9 minute repeatedly, grinds to form smalls, crosses 110-130 mesh sieve (preferred, repeatedly to stir-fry 7 minutes, grind to form smalls, cross 120 mesh sieves stand-by).
6. the preparation method of oral traditional Chinese medicine preparation according to claim 4, is characterized in that: 2. step adds Semen Glycines weight 2.5-3.5 warm water doubly, and sealing is soaked 3-5 hour (preferred, to add the warm water of Semen Glycines weight 3 times, sealing immersion 4 hours).
7. the preparation method of oral traditional Chinese medicine preparation according to claim 4, is characterized in that: step 2. little fire dries 13-18 minute slowly, stickyly removes onal, grind to form smalls, (preferred, little fire dries 15 minutes slowly to cross 90-110 mesh sieve, glue and remove onal, grind to form smalls, cross 100 mesh sieves).
8. the preparation method of oral traditional Chinese medicine preparation according to claim 4, is characterized in that: step 3. thick liquid crosses 170-190 order drainage screen (preferred thick liquid crosses 180 order drainage screens).
9. the preparation method of oral traditional Chinese medicine preparation according to claim 4, is characterized in that: 4. step is smashed to pieces, fries 3-5 minute, grinds to form smalls and crosses 90-110 mesh sieve (preferred, to smash to pieces, fry 4 minutes, grind to form smalls and cross 100 mesh sieves).
10. the preparation method of oral traditional Chinese medicine preparation according to claim 4, is characterized in that: 5. step adds mixed material medicine weight 1.8-2.3 Mel doubly (preferred, to add the Mel of mixed material medicine weight 2 times).
CN201510495893.6A 2015-08-14 2015-08-14 Oral Chinese herb preparation treating post-traumatic brain syndrome and preparing method Pending CN104984038A (en)

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CN1961928A (en) * 2005-11-10 2007-05-16 杨文龙 Blood circulation-activating stasis-removing medicament for treating blood stasis syndrome and preparation process thereof
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CN1961928A (en) * 2005-11-10 2007-05-16 杨文龙 Blood circulation-activating stasis-removing medicament for treating blood stasis syndrome and preparation process thereof
KR20110117923A (en) * 2010-04-22 2011-10-28 경희대학교 산학협력단 Compositions for prevention and treatment of cerebral edema containing the extracts of sesame seed as an active ingredient

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