CN104982444B - A kind of composition pesticide for preventing and treating nematode - Google Patents
A kind of composition pesticide for preventing and treating nematode Download PDFInfo
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- CN104982444B CN104982444B CN201510407276.6A CN201510407276A CN104982444B CN 104982444 B CN104982444 B CN 104982444B CN 201510407276 A CN201510407276 A CN 201510407276A CN 104982444 B CN104982444 B CN 104982444B
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- fluopyram
- nematode
- emamectin
- benzoate
- composition pesticide
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Abstract
The present invention relates to a kind of composition pesticide for preventing and treating nematode, nematode can be effectively prevented and treated.Described composition pesticide active ingredient is emamectin-benzoate and fluopyram, and the weight ratio of the emamectin-benzoate and fluopyram is 1:20‑20:1.Said composition can be configured to the formulations such as missible oil, suspending agent, wettable powder, water dispersible granules, aqueous emulsion, microemulsion, granule, microcapsule formulations, microcapsule suspension suspending agent by well known to a person skilled in the art method.The composition that the present invention is provided reveals obvious synergistic effect to nematode, it is possible to reduce dosage, reduce cost, extension the lasting period, be it is a kind of efficiently, the composition pesticide of low toxicity, low-residual.
Description
Technical field
The present invention relates to technical field of pesticide, more particularly to a kind of composition pesticide for preventing and treating nematode.
Background technology
Root-knot nematode is one of Major Diseases of crop such as Solanaceae, Curcurbitaceae, has generation in China north and south vegetable-growing area, especially
In industrialized agriculture, the crop that plantation nematode is easily infected throughout the year causes root knot nematode disease generally to occur and causes serious warp
Ji loss.China registers less for the medicament of preventing and treating plant root-knot nematode at present, continuous for many years using having developed immunity to drugs, medicine
Effect is poor, and formulation rate is big, so that the problem of causing exceeded residues of pesticides, environmental pollution, high dispenser cost.Therefore it is anxious in agricultural production
It need to develop easy to use and to the efficient medicament of nematode.
Emamectin-benzoate（Referred to as：Emamectin benzoate, English name：Emamectin benzoate, chemical name
Claim：4'- tables-methylamino -4'- deoxidation abamectin benzoates）It is the one kind synthesized since fermented product AVERMECTIN B1
New and effective semisynthetic antibiotics insecticide, it has ultra high efficiency, low toxicity（Preparation is closely nontoxic）, low-residual, the biology such as nuisanceless
The characteristics of agricultural chemicals.Emamectin benzoate is widely used in the preventing and treating of the various pests on the crops such as vegetables, fruit tree, cotton, can strengthen nerve
Matter such as glutamic acid and γ-aminobutyric acid（GABA）Effect so that a large amount of chlorion enters nerve cell, lose cell function
Lose, upset nerve conduction, larva stops feed at once after contact, occurs irreversible paralysis.
Fluopyram（English name：Fluopyram, chemical name：N-[2-（The chloro- 5- of 3-（Trifluoromethyl）- 2- pyrroles
Piperidinyl）The fluoro- O- toluamides of ethyl-- three]）It is a kind of new benzamides series bactericidal agent, is mainly used in preventing and treating capsule bacterium and causes
Disease, suppress mitochondrial respiratory by hindering the electro transfer of succinate dehydrogenase in respiratory chain.Recent research personnel send out
Existing, the medicine has higher bioactivity to root-knot nematode, and new selection is provided for the preventing and treating of root-knot nematode.
The rational mixture of agricultural chemical compound, which has, to be improved prevention effect, delays pest resistance and drug-fast generation, drop
The advantages of low drug cost, expansion insecticidal spectrum.The present invention is compounded emamectin benzoate with fluopyram, with obvious synergy
Effect.
The content of the invention
To solve the pesticide efficacy difference of prior art preventing and treating nematode and formulation rate is big, so as to cause that residues of pesticides are exceeded, ring
The problem of border is polluted, dispenser cost is high, the invention provides a kind of composition pesticide for preventing and treating nematode.Mainly for preventing and treating Solanaceae
Vegetables, cucurbitaceae vegetable, the nematodiasis of romaine lettuce and other leaf vegetables.
The technical scheme is that：
A kind of composition pesticide for preventing and treating nematode, active ingredient is emamectin-benzoate and fluorine pyrrole bacterium acyl
The weight ratio of amine, the emamectin-benzoate and fluopyram is 1:20-20:1.In addition to active ingredient, agriculture
Also include allowing to use and acceptable auxiliary component in agricultural chemicals in drug composition.Insecticides adjuvant includes solvent, wetting agent, disperseed
The one or more of agent, interleaving agent, stabilizer, antifreezing agent, preservative, filler, adhesive etc..The use of auxiliary agent is entered according to formulation
Row selection.
Preferably, the weight ratio of emamectin-benzoate and fluopyram is 1:10-10:1.For
Co-toxicity of pharmaceutical composition of the present invention to nematode is determined, as a result as shown in table 1 progress co-toxicity research, show first
The preventing and treating to nematode mixed with fluopyram of amino abamectin benzoate has obvious synergistic effect, and in the ratio
In the range of synergy it is most obvious.It is furthermore preferred that the weight ratio of emamectin-benzoate and fluopyram is 1:2-2:
1。
The emamectin benzoate of table 1 and co-toxicity result of the fluopyram mixture to nematode
It is 10 by emamectin-benzoate and fluopyram weight ratio:1、5:1、2:1、1:1、1:2、1:5
With 1:10 are used with, and indoor virulence test has been done to nematode second instar larvae, as a result as shown in table 1, and 7 mixed ratios are that synergy is made
With wherein 2:1 and 1:1 co-toxicity coefficient is larger, when ratio is 2:When 1, co-toxicity coefficient highest, i.e. synergistic effect are most obvious.And
Synergistic effect of the synergistic effect of AVM and fluopyram well below emamectin benzoate and fluopyram.
Further, the weight ratio of active ingredient emamectin-benzoate and fluopyram is 2:1.At this
Under weight ratio, synergistic effect is best.
Preferably, active ingredient emamectin-benzoate and fluopyram are in the pesticide combination
Mass fraction in thing is 1-80%.
Further, active ingredient emamectin-benzoate and fluopyram are in the composition pesticide
Mass fraction be 6-20%.The excessive toxicity of active ingredient concentration is too big, there is potential safety hazard, and being typically chosen 6-20% has very
Good preventive effect.
Preferably, the formulation of the composition pesticide be missible oil, suspending agent, wettable powder, water dispersible granules,
One kind in aqueous emulsion, microemulsion, granule, microcapsule formulations, microcapsule suspension suspending agent.
Application of the composition pesticide of the preventing and treating nematode in preventing and treating nematode.
Beneficial effects of the present invention are：
The present invention is compounded using emamectin-benzoate with fluopyram as active ingredient, is killed and is prevented
Controlling nematode has obvious synergistic effect, and field dosage can be greatly decreased, and effectively reduces environmental pollution and residues of pesticides and drops
Low cost.
In addition, emamectin-benzoate is different from the mechanism of action of fluopyram, the lasting period is long, can reduce
Times for spraying, and drug-fast generation can be delayed.It is mainly used in preventing and treating solanaceous vegetable, cucurbitaceae vegetable, romaine lettuce and other leaf vegetables
Nematode.
Furthermore, fluopyram is a kind of efficient bactericide, is applied to after plant root, can play and simultaneous control plant soil-borne
The effect of disease.
Embodiment
Example of formulations
Percentage composition in embodiment is weight percentage.
Embodiment 1：The % fluopyram suspending agents of 4 % emamectin benzoates+2
95 % emamectin benzoate active compounds（Folding hundred） 4 %
96 % fluopyram active compounds（Folding hundred） 2 %
NPE（Wetting dispersing agent） 1 %
Triphenoethyl benzene phenol polyoxyethylene polyoxypropylene block polymer（Wetting dispersing agent） 4 %
Polycarboxylate TERSPERSE 2700（Wetting dispersing agent） 1 %
The % of xanthans 0.1
Organic silicon defoamer 0.1%
The % of ethylene glycol 3
Water complements to 100%.
The each components such as active component, wetting dispersing agent and water are mixed according to the ratio of formula, through 10000 r/min at a high speed
Shearing 5 minutes, adds sand mill and is ground to required particle diameter（Average grain diameter is less than 3 microns）, that is, the % of 4 % emamectin benzoates+2 is made
Fluopyram suspending agent.
Embodiment 2：The fluopyram suspending agent of 5% emamectin benzoate+5%
95 % emamectin benzoate active compounds（Folding hundred） 5 %
96 % fluopyram active compounds（Folding hundred） 5 %
Polycarboxylate TERSPERSE 2700（Wetting dispersing agent） 1 %
Sodium lignin sulfonate（Wetting dispersing agent） 1 %
Phenethyl phenyl polyoxyethylene poly-oxygen propylene aether（Wetting dispersing agent） 5 %
The % of xanthans 0.1
Ethylene glycol 3%
Organic silicon defoamer 0.1%
Water complements to 100%.
The each components such as active component, wetting dispersing agent and water are mixed according to the ratio of formula, through 10000r/min at a high speed
Shearing 5 minutes, adds sand mill and is ground to required particle diameter（Average grain diameter is less than 3 microns）, the fluorine pyrrole of 5% emamectin benzoate+5% is made
Bacterium amide suspending agents.
The fluopyram suspending agent of 3 2% emamectin benzoate of embodiment+4%
95 % emamectin benzoate active compounds（Folding hundred） 2 %
96 % fluopyram active compounds（Folding hundred） 4 %
Calcium lignosulfonate（Wetting dispersing agent） 3.5 %
NNO（Wetting dispersing agent） 2 %
Phenethyl phenyl polyoxyethylene poly-oxygen propylene aether（Wetting dispersing agent） 3.5 %
The % of xanthans 0.1
Ethylene glycol 3%
Organic silicon defoamer 0.1%
Water complements to 100%.
The each components such as active component, wetting dispersing agent and water are mixed according to the ratio of formula, through 10000r/min at a high speed
Shearing 5 minutes, adds sand mill and is ground to required particle diameter（Average grain diameter is less than 3 microns）, the fluorine pyrrole of 2% emamectin benzoate+4% is made
Bacterium amide suspending agents.
The % fluopyram water dispersible granules of 46 % emamectin benzoates of embodiment+3
95 % emamectin benzoate active compounds（Folding hundred） 6 %
96 % fluopyram active compounds（Folding hundred） 3 %
Alkyl naphthalene sulfonic acid condensation polymer（Morwet D-425）（Dispersant） 6 %
Naphthalene sulfonic acid-formaldehyde condensation product NNO（Dispersant） 3 %
Lauryl sodium sulfate（Wetting agent） 1 %
Sodium sulphate（Disintegrant） 0.5 %
Kaolin complements to 100 %.
Active ingredient, dispersant, wetting agent, disintegrant and filler are well mixed by above-mentioned formula, ultra micro air-flow is used
Pulverizer is crushed, and through mediating, then is carried out after extruder grain, drying, screening through sampling analysis, you can the present composition is made
Water dispersible granules.
The % fluopyram granules of 51 % emamectin benzoates of embodiment+2
95 % emamectin benzoate active compounds（Folding hundred） 1.05g
96 % fluopyram active compounds（Folding hundred） 2.08g
1% polyvinyl alcohol water solution 15g
Kaolin 96.72g.
Said components are well mixed, softwood is made, the softwood made is granulated by Squeezinggranulator, dries, that is, makes
Into the % fluopyram granules of 1 % emamectin benzoates+2.
The % fluopyram microcapsule suspension suspending agents of 62 % emamectin benzoates of embodiment+1
The present embodiment prepares microcapsule suspension suspending agent in accordance with the following methods, comprises the following steps that：
Urea and formaldehyde are added in equipped with thermometer, the three-necked flask of agitating device, mol ratio is 1:2.0, after dissolving
The deionized water of 2 times of formaldehyde and weight of urea is added, pH value is adjusted to 8.5 with triethanolamine, is warming up to 70 DEG C, stirring at low speed
Reaction 1 hour, obtains the Lauxite prepolymer aqueous solution.
The % emamectin benzoate active compounds of 3.16g 95 are dissolved completely in 10g cyclohexanone and 17g toluene under normal temperature, added while stirring
Enter the above-mentioned Lauxite prepolymer aqueous solution of 17g, the aqueous sodium polyacrylates of 20g 5%, 10000 revs/min of high speed shears are formed surely
Fixed O/W emulsions；Rotating speed is reduced to 400 revs/min, point 5 batches of addition 1M hydrochloric acid regulation systems pH value 2.5, polycondensation in 60 minutes
Reaction 1 hour；Thereafter 60 DEG C of solidification cyst walls are warming up to and add sodium hydroxide regulation pH value 7.0 after 1 hour, addition 2.5g tweens-
80 and 2.5g lauryl sodium sulfate, adds 1% xanthan gum solution 10g, adds water and supply 100g, that is, obtain 3% emamectin benzoate
Microcapsule suspending agent.
Weigh the fluopyram active compounds of 3.13g 96%, 2g styrene phenol formaldehyde resin polyoxyethylene poly-oxygen propylene aethers, 2g
Polycarboxylate, 0.5g NPEs, 0.18g xanthans, 3g ethylene glycol, organic silicon defoamer 0.2g, water is supplied
100g.Each component is weighed according to above-mentioned formula to be placed in beaker, high-speed shearing machine is opened 30 minutes, then sand mill 1500
Rev/min grinding, detection sample particle diameter more than 95% at 1-5 microns, average grain diameter obtains 3% fluorine pyrrole bacterium acyl below 3 microns
Amine suspending agent.
3 % emamectin benzoates microcapsule suspending agents and 3 % fluopyrams suspending agents are compared 2 according to weight:1 well mixed produces
Arrive, the fluopyram microcapsule suspension suspending agent of 2% emamectin benzoate+1%.
Field control effectiveness test embodiment
Carry out the fluopyram suspending agent of 4% emamectin benzoate+2%, the fluopyram suspending agent of 5% emamectin benzoate+5% and 2 % first dimension
Field control effectiveness test of the % of salt+1 fluopyram microcapsule suspension suspending agents to root-knot nematode.
Choose and cultivate the consistent tomato seedling of 40 d growing ways, it is by the inoculum concentration of every plant of 1000 larvas that the age of root-knot nematode two is young
Worm suspension instils in the root of plant respectively.Two 220 grams/ha and 260 grams/ha of effective ingredient consumptions, 24 h are set
Decoction pouring root, every plant of 500mL decoction, separately set CK afterwards（Only it is inoculated with nematode, not dispenser）, respectively handle and be repeated 3 times.All plant with
Machine is arranged, cultivation condition uniformity.
80 d after processing, is slowly withdrawn plant root and cleans, record incidence.
Root knot grade scale is as follows：
0 grade：Health of root, without root knot；1 grade：The small root knot of only a few could be found by going through；2 grades：Root knot picture
1 grade of size but quantity is slightly more；3 grades：A large amount of small root knots, are grown together sometimes, and root functionality is impaired not to be weighed；4 grades：A large amount of rootlets
Knot, there is some big root knots, mostly several still to have function；5 grades：25% root system seriously ties goitre and loss of function；6 grades：50%
The serious knot goitre of system and loss of function；7 grades：75% root system seriously ties goitre, loss of function；8 grades：Without healthy root, in plant nutrient
It is disconnected；9 grades：Root system all knot goitre and rotten, plant death；10 grades：Plant and root system are dead.
。
Table 2 prevents and treats root-knot nematode field control effectiveness test result
As can be seen from Table 2：
1st, when effective ingredient consumption is identical, the prevention effect for the composition that emamectin benzoate is compounded with fluopyram is higher than two
Plant the effect that medicament is used alone, wherein embodiment 1 and embodiment 6（Emamectin benzoate：Fluopyram=2:1）Preventive effect highest.This
The research and development and promotion conference of invention produce very big economic value, and the preventing and treating tool of crop root-knot nematode is of great significance.
2nd, when substituting emamectin benzoate using AVM, under same ratio and consumption, its preventive effect is poorer than the present invention
9.7%-12.03%。
3rd, the % fluopyram microcapsule suspension suspending agents of 2 % emamectin benzoates+1 and the fluopyram of 4% emamectin benzoate+2% suspend
Agent is suitable to the preventive effect of root-knot nematode, even better；I.e. when emamectin benzoate and fluopyram ratio and consumption phase simultaneously as
Formulation difference, because emamectin benzoate is prepared to microcapsules, the extension of its lasting period, therefore the microcapsule suspending agent and fluorine pyrrole of emamectin benzoate
Mixing formulation obtained by the mixing of bacterium amide suspending agents is more prominent to the prevention effect of root-knot nematode.
Claims (5)
1. a kind of composition pesticide for preventing and treating nematode, it is characterised in that：Active ingredient be emamectin-benzoate with
The weight ratio of fluopyram, the emamectin-benzoate and fluopyram is 1:2-2:1；The agricultural chemicals group
The formulation of compound is microcapsule suspension suspending agent；The composition pesticide is hanged by the microcapsules of emamectin-benzoate
Floating agent is formed with fluopyram suspending agent compounding.
2. the composition pesticide of nematode is prevented and treated as claimed in claim 1, it is characterised in that：Active ingredient emamectin benzoate benzene
The weight ratio of formates and fluopyram is 2:1.
3. the composition pesticide of nematode is prevented and treated as claimed in claim 1, it is characterised in that：Active ingredient emamectin benzoate benzene
Formates is 1-80% with mass fraction of the fluopyram in the composition pesticide.
4. the composition pesticide of nematode is prevented and treated as claimed in claim 3, it is characterised in that：Active ingredient emamectin benzoate benzene
Formates is 6-20% with mass fraction of the fluopyram in the composition pesticide.
5. application of the composition pesticide of preventing and treating nematode in preventing and treating nematode as claimed in claim 1.
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| CN201510407276.6A CN104982444B (en) | 2015-07-13 | 2015-07-13 | A kind of composition pesticide for preventing and treating nematode |
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| CN201510407276.6A CN104982444B (en) | 2015-07-13 | 2015-07-13 | A kind of composition pesticide for preventing and treating nematode |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105532681B (en) * | 2016-01-28 | 2017-12-08 | 山东农业大学 | Line composition is sterilized and killed to a kind of ternary with synergistic function |
| CN110178846A (en) * | 2019-04-24 | 2019-08-30 | 南京生兴有害生物防治技术股份有限公司 | A kind of preparation of Bursaphelenchus xylophilus immunizing agent |
| CN110150275A (en) * | 2019-05-29 | 2019-08-23 | 允发化工（上海）有限公司 | Microcapsule suspension-suspendinagent agent and preparation method containing avermectin and fluopyram |
| CN111820229B (en) * | 2020-06-24 | 2021-12-28 | 河北威远生物化工有限公司 | Fluopyram-containing nematicidal composition and application thereof |
| CN113021545B (en) * | 2021-03-11 | 2023-08-25 | 鹤山市木森木制品有限公司 | Pestilence log insecticidal sterilization liquid medicine, treatment device using liquid medicine for insecticidal sterilization and treatment method thereof |
| CN114557359A (en) * | 2022-01-14 | 2022-05-31 | 杭州益森键生物科技有限公司 | Pesticide composition for preventing and treating pine wood nematode disease and compound preparation and application thereof |
| CN114451415A (en) * | 2022-01-20 | 2022-05-10 | 中国林业科学研究院森林生态环境与自然保护研究所 | Preventive preparation for preventing and controlling pine wilt disease |
| CN114503990B (en) * | 2022-01-27 | 2023-09-01 | 陕西先农生物科技有限公司 | Suspending agent containing avermectin and fluopyram |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101263816B (en) * | 2007-03-13 | 2010-07-21 | 来燕学 | Emamectin benzoate-chlorfenapyr injection for preventing pine wilt disease |
| CN101627762A (en) * | 2009-08-18 | 2010-01-20 | 青岛星牌作物科学有限公司 | Composite of insecticides, miticides and nematicide with synergistic effect and application |
| CN104585190A (en) * | 2014-12-30 | 2015-05-06 | 海利尔药业集团股份有限公司 | Nematicide composition containing abamectin and fluopyram |
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