CN104958714A - Tablet for treating acute suppurative tonsillitis of children and preparation method of tablet - Google Patents

Abstract

The invention discloses a tablet for treating acute suppurative tonsillitis of children. The tablet is prepared from the following raw materials in parts by weight: 8-10 parts of astragalus root, 20-30 parts of quails, 15-20 parts of peaches, 45-55 parts of wheat, 8-10 parts of coptis chinensis, 9-12 parts of skullcap, 5-8 parts of lacca, 2-5 parts of radix trichosanthis, 10-15 parts of burdock, 5-8 parts of alpine yarrow herb, 7-9 parts of Chinese mahonia leaves, 3-5 parts of hylocereus undatus, 4-7 parts of curcuma zedoary, 8-10 parts of pomegranate bark, 15-20 parts of herba portulacae, 5-8 parts of honey-fried licorice roots, 10-13 parts of fructus forsythia and 8-10 parts of platycodon grandiflorum. A pure traditional Chinese medicine preparation is adopted by the tablet; the defects of western medicine treatment are avoided; the tablet is safe, and free of toxic or side effect; the medicine resistance is not easy to generate; the diseases can be rapidly relieved and removed; both symptoms and root causes of the disease are treated; the immunity of the patients can be improved; and the tablet is especially suitable for young children for use.

Description

A kind ofly treat tablet of children's acute suppurative tonsillitis and preparation method thereof

Technical field

The present invention relates to the field of Chinese medicines, particularly a kind ofly treat tablet of children's acute suppurative tonsillitis and preparation method thereof.

Background technology

Children's's suppurative tonsillitis is a kind of commonly encountered diseases of children's, belongs to the upper respiratory disease caused by bacteriological infection.In the middle of the respiratory tract infection case of children's, children's's suppurative tonsillitis accounts for about 10% ~ 15%.Children's's suppurative tonsillitis onset is anxious, and high heat, pharyngalgia is obvious, and adenoid vegetation, antiadoncus, when swallowing more so, can cause infant refusing to eat, check visible pharyngeal congestion, has yellow-white pus point or pus tongue, cervical lymph node enlargement above the tonsil of enlargement.Due to antibacterial and viral infection, wherein antibacterial is more common.Pathogen mostly is Hemolytic streptococcus, staphylococcus, streptococcus pneumoniae.In the throat that these antibacterials are present in people usually and tonsil crypts, under normal circumstances, the continuous secretion of and mucous gland complete due to tonsil gland superficial epithelium, can discharge antibacterial from crypts mouth with the epithelium antibacterial that come off, therefore remain the health of body.When body because of overtired, suffer from cold, after local is subject to the impact of physics or chemical factor, when resistance declines, tonsilar blood fortune reduces, glandular secretion function declines, and epithelium defence capability reduces, and namely antibacterial takes advantage of a weak point, and grows breeding, causes almond inflammation.This disease can be divided into acute suppurative tonsillitis and chronic suppurative tonsillitis two kinds.Wherein, acute suppurative tonsillitis onset urgency, aversion to cold, Gao Rekeda 39 ~ 40 DEG C, especially child Ke Yingao heat and producing twitch, vomiting or the symptom such as lethargy, inappetence, constipation and systemic pain, larger misery and torment can be brought to patient, infringement patient health.And if acute tonsillitis is treated not in time or is treated not thorough, can be easy to transfer chronic tonsillitis to, Relapse rate is caused to show effect, under the stimulation of Chronic inflammation, tonsil may lose normal function on the contrary and be converted into harmful " focus ", can cause as multiple complications such as otitis media, sinusitis, glomerulonephritis, myocarditis, rheumatic heart disease, rheumatic arthritis.

At present, common infusions or oral antibiotic treatment children's acute suppurative tonsillitis, but antibiotic therapy exists costly, easily develops immunity to drugs, and reduces the shortcoming of resistance of human body, and causes comparatively major injury to the health of child.China's traditional Chinese medical science is of extensive knowledge and profound scholarship, and children's's suppurative tonsillitis is classified as " tonsillitis " category by theory of Chinese medical science, and its Basic disease cause pathogenesis is exuberant lung-stomach heat.Throat is department's diet, row is breathed, soniferous organ, and upper even oral cavity, lower logical lung stomach is again the communications centre of running course of channel.Larynx, belonging to lung system, communicates with lung, is the thoroughfare of gas discrepancy; Pharynx is belonging to stomach system, and communicating with stomach, is the passage of water paddy.Children's is the body of immature yin and yang, gas when susceptible is non-.Clinical to have sore throat, swelling, suppuration be feature.The current traditional Chinese medical science is to the treatment spininess of this disease to the comprehensive conditioning human body of pathogenic root, but most method onset is comparatively slow, can not contain the state of an illness fast, cannot rapid recovery patient suffering, especially child patient very easily produces to this long-term treatment means psychology of conflicting, and mismatches treatment, affects the treatment.

Summary of the invention

The present invention according to traditional Chinese medical science Synergy, for the cause of disease and the disease of children's acute suppurative tonsillitis, from entirety, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, there is provided a kind of and treat tablet of children's acute suppurative tonsillitis and preparation method thereof, this tablet adopts pure Chinese medicinal preparation, avoids the drawback of western medical treatment, safe without toxic side effect, not easily produce drug resistance, disease can be eliminated, this disease for the treatment of both the principal and secondary aspects of a disease by rapid recovery, patient's autoimmunity can be improved, be particularly useful for children and use.

To achieve these goals, technical scheme provided by the invention is as follows:

Treat a tablet for children's acute suppurative tonsillitis, raw material composition and the parts by weight of making described tablet are: Radix Astragali 8-10 part, Carnis Coturnicis japonicae 20-30 part, Fructus Persicae 15-20 part, Semen Tritici aestivi 45-55 part, Rhizoma Coptidis 8-10 part, Radix Scutellariae 9-12 part, Lacca 5-8 part, Radix Trichosanthis 2-5 part, Fructus Arctii 10-15 part, achillea millefolium 5-8 part, Folium Mahoniae 7-9 part, Hylocereus undatus 3-5 part, Rhizoma Curcumae 4-7 part, Pericarpium Granati 8-10 part, Herba Portulacae 15-20 part, Radix Glycyrrhizae Preparata 5-8 part, Fructus Forsythiae 10-13 part, Radix Platycodonis 8-10 part.

Further, raw material composition and the parts by weight of making described tablet are: Radix Astragali 8 parts, Carnis Coturnicis japonicae 20 parts, Fructus Persicae 15 parts, Semen Tritici aestivi 45 parts, Rhizoma Coptidis 8 parts, Radix Scutellariae 9 parts, Lacca 5 parts, Radix Trichosanthis 2 parts, Fructus Arctii 10 parts, achillea millefolium 5 parts, Folium Mahoniae 7 parts, Hylocereus undatus 3 parts, Rhizoma Curcumae 4 parts, Pericarpium Granati 8 parts, Herba Portulacae 15 parts, Radix Glycyrrhizae Preparata 5 parts, Fructus Forsythiae 10 parts, Radix Platycodonis 8 parts.

Further, raw material composition and the parts by weight of making described tablet are: Radix Astragali 10 parts, Carnis Coturnicis japonicae 30 parts, Fructus Persicae 20 parts, Semen Tritici aestivi 55 parts, Rhizoma Coptidis 10 parts, Radix Scutellariae 12 parts, Lacca 8 parts, Radix Trichosanthis 5 parts, Fructus Arctii 15 parts, achillea millefolium 8 parts, Folium Mahoniae 9 parts, Hylocereus undatus 5 parts, Rhizoma Curcumae 7 parts, Pericarpium Granati 10 parts, Herba Portulacae 20 parts, Radix Glycyrrhizae Preparata 8 parts, Fructus Forsythiae 13 parts, Radix Platycodonis 10 parts.

Further, raw material composition and the parts by weight of making described tablet are: Radix Astragali 9 parts, Carnis Coturnicis japonicae 25 parts, Fructus Persicae 17 parts, Semen Tritici aestivi 50 parts, Rhizoma Coptidis 9 parts, Radix Scutellariae 11 parts, Lacca 7 parts, Radix Trichosanthis 3 parts, Fructus Arctii 12 parts, achillea millefolium 6 parts, Folium Mahoniae 8 parts, Hylocereus undatus 4 parts, Rhizoma Curcumae 6 parts, Pericarpium Granati 9 parts, Herba Portulacae 18 parts, Radix Glycyrrhizae Preparata 7 parts, Fructus Forsythiae 11 parts, Radix Platycodonis 9 parts.

The invention also discloses the preparation method of the tablet of described treatment children's acute suppurative tonsillitis, comprise the following steps:

(1) Carnis Coturnicis japonicae unhairing is cut into small pieces after going internal organs to clean, and adds the distilled water of its mass fraction 20 times, decocts 45 minutes at 110 DEG C, and cross 1000 order drainage screens, gained filtrate is for subsequent use, and gained Carnis Coturnicis japonicae block is boned and stayed meat for subsequent use;

(2) Semen Tritici aestivi is cleaned, and puts into steamer 120 DEG C of steaming and decoctings 20 minutes, and the Semen Tritici aestivi cooked mixes with step 1 gained quail meat to be put into 80 DEG C, baking oven and dry 60 minutes, and gained drying composite super micron mill is pulverized, and mistake 500 mesh sieves obtain powder;

(3) Radix Astragali, Rhizoma Coptidis, Radix Scutellariae, Lacca, Radix Trichosanthis, Fructus Arctii, achillea millefolium, Folium Mahoniae, Hylocereus undatus, Rhizoma Curcumae, Pericarpium Granati, Radix Glycyrrhizae Preparata, Fructus Forsythiae, Radix Platycodonis add step (1) gained filtrate and soak 1 hour, slow fire boiling 1 hour, cross 1000 order drainage screens after decocting, gained filtrate is dried in the air cool for subsequent use to room temperature;

(4) Fructus Persicae enucleation, mixes with Herba Portulacae and cleans, and add after step (3) gained filtrate is squeezed the juice and leave standstill 2 hours, cross 1000 filter screen filtration, gained filter vacuum is concentrated into the thick paste that relative density is 1.30 ± 0.02 (60 DEG C);

(5) add in thick paste obtained in step (4) by powder obtained in step (2), stirring and evenly mixing, granulate, granulate, tabletting is made sheet and is weighed the tablet of 0.5 gram and get final product.

The using method of this tablet: three times on the oral one, one time 6.

The Basic disease cause pathogenesis of children's's suppurative tonsillitis is exuberant lung-stomach heat, and throat connects oral cavity, and lower logical lung stomach is again the communications centre of running course of channel, and larynx, belonging to lung system, communicates with lung, is the thoroughfare of gas discrepancy; Pharynx is belonging to stomach system, and communicating with stomach, is the passage of water paddy.Children's is the body of immature yin and yang, gas when susceptible is non-.Tablet of the present invention takes heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, anti-inflammatory analgetic, the method for invigorating the spleen and replenishing QI treats this disease, according to Chinese medical theory determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, raw material of Chinese medicine is screened by great many of experiments, refining agent method, make each efficacy of drugs produce synergism, thus reach the effect for the treatment of both the principal and secondary aspects of a disease.In the crude drug chosen: Fructus Persicae: sweet in the mouth acid, warm in nature, there is tonifying QI to produce body fluid, the merit of promoting blood circulation to remove stagnancy, hinder dryness of the intestine constipation for Tianjin, blood stasis lump, hepatosplenomegaly etc., Semen Tritici aestivi: sweet in the mouth, cool in nature, there is invigorating spleen and nourishing heart kidney tonifying, the merit that heat extraction quenches the thirst, for dry mouth and throat, dysphoria, inappetence etc., Radix Astragali, has effect of benefiting QI for strengthening the superficies, inducing diuresis to remove edema, detoxification, granulation promoting, is applicable to spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, carbuncle and does not burst or burst and the disease such as not hold back for a long time, Carnis Coturnicis japonicae: sweet in the mouth, property is put down, and have tonifying five ZANG-organs, gas in benefit, the merit of eliminating damp-heat, for malnutrition, asthenia is thin and weak, chronic diarrhea chronic dysentery, the diseases such as inappetence, Rhizoma Coptidis: bitter in the mouth, cold, heat clearing and damp drying, eliminating fire and detoxication, anti-inflammation, for damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, toothache, quench one's thirst, carbuncle furuncle, external treatment eczema, eczema, auditory meatus is suppurated, it is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs, for conjunctival congestion, aphtha, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting, tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted, cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting, for incoordination between the liver and stomach, vomiting acid regurgitation, Rhizoma Coptidis and Radix Glycyrrhizae are share can the effect of obvious its anti-Staphylococcus aureus of gain, Radix Scutellariae: bitter in the mouth, cold in nature, there are heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive, cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle, the clinical antibiotic property of Radix Scutellariae is better than Rhizoma Coptidis, and does not develop immunity to drugs, Lacca: bitter, flat, clearing away heat,cooling blood and removing toxin, removing blood stasis with potent drugs promoting the circulation of QI to relieve pain, Lacca can detoxify and invigorate blood circulation, and again without the trouble that work rushes down, this is that it surpasses the place of Radix Arnebiae (Radix Lithospermi), Fructus Arctii: dispelling wind and heat pathogens, lung qi dispersing rash, subduing swelling and detoxicating.Control cough due to pathogenic wind-heat, laryngopharynx swelling and pain, macule is not saturating, and rubella is had an itch, carbuncle sore tumefacting virus; Radix Trichosanthis: clearing away heat and promoting production of body fluid, detumescence and apocenosis, for calentura excessive thirst, lung-heat type cough, interior-heat is quenched one's thirst, sore swollen toxin; Achillea millefolium: bitter, acid, flat, anti-inflammation, removing toxic substances analgesia.With controlling mastitis, acute tonsillitis, appendicitis, pyelitis etc., rheumatalgia, traumatic injury, innominate toxic swelling, venom etc., have inhibitory action to staphylococcus aureus, dysentery bacterium, escherichia coli, bacillus pyocyaneus; Folium Mahoniae: bitter, cool, heat clearing away tonify deficiency, removing pathogenic heat from blood and toxic substance from the body, double circulation of qi promoting divides, and preventing phlegm from forming and stopping coughing cures mainly hemoptysis of pulmonary tuberculosis, osteopyrexia and fever, dizziness and tinnitus, lassitude loin and legs, vexed conjunctival congestion, the diseases such as anemopyretic cold; Hylocereus undatus: cold nature, sweet in the mouth, clearing heat and moistening lung, control the hot xeropulmonary cough of expectorant; Rhizoma Curcumae: bitter, pungent, temperature, blood stasis dispelling stimulates the menstrual flow eliminating mass, for amenorrhea stomachache, lump in the abdomen mass in the abdomen etc. that blood stasis is depressed, has the effect of removing blood stasis, promoting the circulation of QI to relieve pain; Pericarpium Granati: convergence, antibacterial.In vitro tests has antibacterial action to bacillus pyocyaneus, bacterium flexneri, Bacillus typhi, also has inhibitory action in various degree to various skin fungus.Also has resisiting influenza virus effect; Herba Portulacae: cold in nature, sweet in the mouth acid; Enter the heart, liver, spleen, large intestine channel, have that removing dampness is antipruritic, clearing heat for detumescence, heat-clearing and toxic substances removing, diuretic dries, loose blood detumescence, dust-collection sterilization, anti-inflammatory analgetic, the effect of hemostasis removing heat from blood, Herba Portulacae has stronger inhibitory action to dysentery bacterium, Bacillus typhi and escherichia coli, can be used for the auxiliary treatment of various inflammation, have the title of " natural antibiotics ", simultaneously Herba Portulacae is also rich in vitamin C, and vitamin C has good antioxidation can whitening nourishes rough skin; Radix Glycyrrhizae Preparata: containing number of chemical compositions such as glycyrrhizin, enoxolone, Angelica Polysaccharide, there is antiinflammatory and anti-allergy action, scalable body's immunity, antitumor and analgesic effect, therefore the primary efficacy of Radix Glycyrrhizae Preparata is and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription; Fructus Forsythiae: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, dispelling wind and heat pathogens, modern medicine study confirms, Fructus Forsythiae concentrated decotion has antibacterial action in vitro, can suppress Bacillus typhi, Salmonella paratyphi, escherichia coli, dysentery bacterium, diphtheria corynebacterium and vibrio cholera, staphylococcus, streptococcus etc.; Radix Platycodonis: open lung qi dispersing gas, evacuation of pus of eliminating the phlegm, controls exogenous cough, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, and dysentery is suffered from abdominal pain.

In all medicines, Herba Portulacae and Fructus Forsythiae are monarch drug, play the effect of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, anti-inflammatory analgetic altogether, for this disease of cause of disease treatment for diseases.Radix Astragali, Carnis Coturnicis japonicae, Fructus Persicae, Semen Tritici aestivi, Rhizoma Coptidis, Radix Scutellariae, Lacca, Radix Trichosanthis, Fructus Arctii, achillea millefolium, Folium Mahoniae, Hylocereus undatus, Rhizoma Curcumae, Pericarpium Granati are ministerial drug; Wherein, Rhizoma Coptidis, Radix Scutellariae, Lacca, achillea millefolium, Folium Mahoniae, Hylocereus undatus, Radix Trichosanthis, Fructus Arctii, Carnis Coturnicis japonicae can the effect of gain monarch drug heat-clearing and toxic substances removing, and effective eliminating fire and detoxication, brings down a fever fast, and reduction of patient is uncomfortable, avoids hyperpyrexia to cause other complication; Radix Astragali, Fructus Persicae, Fructus Arctii, Radix Trichosanthis, Lacca, Rhizoma Curcumae can the effects of gain monarch drug dispersing swelling and dissipating binds, eliminate pharyngeal hyperemia, symptom that tonsil pus, lymph node swell and ache; Rhizoma Coptidis, Radix Scutellariae, achillea millefolium, Folium Mahoniae, Rhizoma Curcumae, Pericarpium Granati and monarch drug play the effect that antiinflammatory relieves the pain altogether, and auxiliary monarch drug effectively kills pathogenic bacterium fast, and rapid recovery patient affected part pain, alleviates patient suffering; Radix Astragali, Carnis Coturnicis japonicae, Fructus Persicae, Semen Tritici aestivi play the effect of invigorating the spleen and replenishing QI, can alleviate patient body deficient syndrome shape, regulate body, improve patient's autoimmunity, promote Rehabilitation.Radix Glycyrrhizae Preparata is assistant, plays harmonizing yingfen and weifen, the effect of warming spleen and stomach for dispelling cold, and meanwhile, Rhizoma Coptidis and Radix Glycyrrhizae are share can obvious its antibacterial action of gain.Radix Platycodonis for drawing, can priming up, promote effective ingredient act on affected part.Medicine of the present invention is pure Chinese medicinal preparation, selected medical material compatibility is suitable, and adopt modern advanced medical pharmaceutical technology to make, can while effectively treating this disease, the symptom that rapid recovery patient Gao Re, pharyngalgia, pharyngeal hyperemia, tonsil pus, lymph node swell and ache, nurses one's health children patient simultaneously, strengthens infant autoimmunity, there is treating both the principal and secondary aspects of a disease rapid-action, the remarkable advantage of safe without toxic side effect.

Beneficial effect of the present invention is: the invention provides and a kind ofly treat tablet of children's acute suppurative tonsillitis and preparation method thereof, this tablet adopts pure Chinese medicinal preparation, avoid the drawback of western medical treatment, safe without toxic side effect, not easily produce drug resistance, disease can be eliminated, this disease for the treatment of both the principal and secondary aspects of a disease by rapid recovery, patient's autoimmunity can be improved, be particularly useful for children and use.

This tablet is for the disease of children's acute suppurative tonsillitis and the cause of disease, in conjunction with PATIENT POPULATION's feature, adopt pure Chinese medicinal preparation, take anti-inflammatory analgetic, heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, the Therapeutic Method of invigorating the spleen and replenishing QI treats this disease, the tablet of pure Chinese medicinal preparation, more safe and effective compared to antibiotic, selected medical material compatibility is suitable, and adopt modern advanced medical pharmaceutical technology to make, can remove scorchingly hot fast for the cause of disease, dispersing swelling and dissipating binds, kill pathogenic bacterium, quick antiinflammatory, bring down a fever, relieve the pain, detumescence, eliminate pharyngeal hyperemia, tonsil pus, lymph node swells and ache symptom, there is treating both the principal and secondary aspects of a disease rapid-action, can effectively reduction of patient be painful, the remarkable advantage of safe without toxic side effect, take into full account that feature that patient has a delicate constitution takes the method for invigorating the spleen and replenishing QI simultaneously, regulate patient's body, improve patient's autoimmunity, thus promote that patient recovers, especially be adapted to child use.

The raw material playing invigorating the spleen and replenishing QI effect in all medicines mostly is the product of temperature compensation, conditioning patient body deficient syndrome shape that can be incremental, avoids patient's void do not mended and run counter to desire, in this prescription, the crude drug of heat-clearing and toxic substances removing mostly is cold, be that assistant can play harmonizing yingfen and weifen, the effect of warming spleen and stomach for dispelling cold with Radix Glycyrrhizae, avoid Long-term taking medicine to damage patient body, with Radix Platycodonis for drawing, throat can be gone upward to by priming, promote that effective ingredient acts on affected part, strengthen drug effect.The dosage form of tablet is more easily swallowed compared to traditional Chinese medicine decoction, and infant uses and not easily produces psychology of conflicting, and favourable have infant to coordinate partner treatment, guarantees curative effect.

Detailed description of the invention

According to following embodiment, the present invention may be better understood.But those skilled in the art will readily understand, concrete material proportion, process conditions and result thereof described by embodiment only should can not limit the present invention described in detail in claims yet for illustration of the present invention.

Embodiment 1

Treat a tablet for children's acute suppurative tonsillitis, raw material composition and the parts by weight of making described tablet are: Radix Astragali 8 parts, Carnis Coturnicis japonicae 20 parts, Fructus Persicae 15 parts, Semen Tritici aestivi 45 parts, Rhizoma Coptidis 8 parts, Radix Scutellariae 9 parts, Lacca 5 parts, Radix Trichosanthis 2 parts, Fructus Arctii 10 parts, achillea millefolium 5 parts, Folium Mahoniae 7 parts, Hylocereus undatus 3 parts, Rhizoma Curcumae 4 parts, Pericarpium Granati 8 parts, Herba Portulacae 15 parts, Radix Glycyrrhizae Preparata 5 parts, Fructus Forsythiae 10 parts, Radix Platycodonis 8 parts.

The preparation method of this tablet comprises the following steps:

(1) Carnis Coturnicis japonicae unhairing is cut into small pieces after going internal organs to clean, and adds the distilled water of its mass fraction 20 times, decocts 45 minutes at 110 DEG C, and cross 1000 order drainage screens, gained filtrate is for subsequent use, and gained Carnis Coturnicis japonicae block is boned and stayed meat for subsequent use;

(2) Semen Tritici aestivi is cleaned, and puts into steamer 120 DEG C of steaming and decoctings 20 minutes, and the Semen Tritici aestivi cooked mixes with step 1 gained quail meat to be put into 80 DEG C, baking oven and dry 60 minutes, and gained drying composite super micron mill is pulverized, and mistake 500 mesh sieves obtain powder;

(3) Radix Astragali, Rhizoma Coptidis, Radix Scutellariae, Lacca, Radix Trichosanthis, Fructus Arctii, achillea millefolium, Folium Mahoniae, Hylocereus undatus, Rhizoma Curcumae, Pericarpium Granati, Radix Glycyrrhizae Preparata, Fructus Forsythiae, Radix Platycodonis add step (1) gained filtrate and soak 1 hour, slow fire boiling 1 hour, cross 1000 order drainage screens after decocting, gained filtrate is dried in the air cool for subsequent use to room temperature;

(4) Fructus Persicae enucleation, mixes with Herba Portulacae and cleans, and add after step (3) gained filtrate is squeezed the juice and leave standstill 2 hours, cross 1000 filter screen filtration, gained filter vacuum is concentrated into the thick paste that relative density is 1.30 ± 0.02 (60 DEG C);

(5) add in thick paste obtained in step (4) by powder obtained in step (2), stirring and evenly mixing, granulate, granulate, tabletting is made sheet and is weighed the tablet of 0.5 gram and get final product.

The using method of this Chinese medicinal tablet: three times on the oral one, one time 6.

Embodiment 2

Treat a tablet for children's acute suppurative tonsillitis, raw material composition and the parts by weight of making described tablet are: Radix Astragali 10 parts, Carnis Coturnicis japonicae 30 parts, Fructus Persicae 20 parts, Semen Tritici aestivi 55 parts, Rhizoma Coptidis 10 parts, Radix Scutellariae 12 parts, Lacca 8 parts, Radix Trichosanthis 5 parts, Fructus Arctii 15 parts, achillea millefolium 8 parts, Folium Mahoniae 9 parts, Hylocereus undatus 5 parts, Rhizoma Curcumae 7 parts, Pericarpium Granati 10 parts, Herba Portulacae 20 parts, Radix Glycyrrhizae Preparata 8 parts, Fructus Forsythiae 13 parts, Radix Platycodonis 10 parts.

The preparation method of described tablet is identical with embodiment 1 with using method.

Embodiment 3

Treat a tablet for children's acute suppurative tonsillitis, raw material composition and the parts by weight of making described tablet are: Radix Astragali 9 parts, Carnis Coturnicis japonicae 25 parts, Fructus Persicae 17 parts, Semen Tritici aestivi 50 parts, Rhizoma Coptidis 9 parts, Radix Scutellariae 11 parts, Lacca 7 parts, Radix Trichosanthis 3 parts, Fructus Arctii 12 parts, achillea millefolium 6 parts, Folium Mahoniae 8 parts, Hylocereus undatus 4 parts, Rhizoma Curcumae 6 parts, Pericarpium Granati 9 parts, Herba Portulacae 18 parts, Radix Glycyrrhizae Preparata 7 parts, Fructus Forsythiae 11 parts, Radix Platycodonis 9 parts.

The preparation method of described tablet is identical with embodiment 1 with using method.

Embodiment 4 toxicity test

NIH mice 40, SPF level, body weight 20 ~ 25g, carries out acute toxicity test.Mice is divided into four groups at random, often organizes 10, male and female half and half, i.e. matched group and 3 administration groups, fasting 12 hours before experiment; The tablet of embodiments of the invention 1 to 3 is dissolved in water respectively, (concentration is 3g crude drug/ml to give 3 administration group gavages respectively, maximum concentration), gavage volume is 10ml/kg (namely unit dosage form is crude drug 30/kg), matched group gives normal saline, administration in a day 3 times, delivery time 4 hours, Continuous Observation 14 days after administration, and record mice toxic reaction and death toll.Experimental result shows: compare with matched group, and after administration, mice has no notable difference, and experiment Continuous Observation 14 days, mouse systemic situation, diet, drinking-water, body weight increase all normal.Mouse oral gavage Chinese medicinal tablet LD50>30 crude drug/kg of the present invention, every day, maximum dosage-feeding was 90 crude drugs/kg/ day.Chinese medicine clinical application amount of the present invention be 9g crude drug/day/people, adult body weight in 60KG, average dosage is 0.15g crude drug/kg/ day.By weighing machine: the dosis tolerata of mice (average weight is in 22.5g) oral administration gavage tablet of the present invention is 600 times of quantity.Therefore Chinese medicinal tablet toxicity of the present invention is low, clinical drug safety.

Embodiment 5 clinical trial:

Random selecting 150 acute suppurative tonsillitis infants carry out clinical experiment, children age 3 ~ 9 years old, 5 years old mean age.Patient is divided into 3 groups of these diseases of tablet in treatment respectively in embodiment 1 to 3 on probation, three times on the oral one, one time 6, within 7th, be a course for the treatment of, investigate the curative effect of tablet of the present invention, the evaluation criterion of curative effect is:

Effective: temperature recovery is normal, pharyngalgia, pharyngeal hyperemia, lymph node swell and ache, tonsil purulence thing disappears or substantially disappears.

Take a turn for the better: more first the examining of body temperature decreases, but does not recover normal, and symptom, the signs such as pharyngalgia, pharyngeal hyperemia, tonsil purulence thing alleviate.

Invalid: clinical symptoms, sign are without improvement or aggravation.

	Embodiment 1	Embodiment 2	Embodiment 3
				Significantly	38	42	40
Take a turn for the better	11	8	10
				Invalid	1	0	0
Effective percentage (%)	98	100	100

Clinical model case:

Zhang, female, 8 years old, without inducement, patient occurs that bottleneck throat swells and ache discomfort before seeking medical advice 2, pharyngeally rush blood, lymph node swells and ache, tonsil has a large amount of purulence thing, swallow process pain obvious, take cefalexin Tablet voluntarily, DeGrain, then examine, the same day body temperature of seeking medical advice is up to 39.1 DEG C, be children's's suppurative tonsillitis on inspection, after taking 1 course for the treatment of of tablet of the embodiment of the present invention 1, temperature recovery is normal, pharyngalgia, pharyngeal hyperemia, tonsil purulence thing, the lymph node symptom that swells and ache obviously alleviates, adhere to 2 courses for the treatment of of use, whole disease disappears, patient fully recovers.Follow up a case by regular visits to 1 month, the state of an illness is without recurrence.

Grandson, female, 6 years old, morning on the same day of seeking medical advice, patient occurred that bottleneck throat swelled and ache malaise symptoms, pharyngeally rush blood, swallow process pain obvious, body temperature is up to 38.5 DEG C, is children's's suppurative tonsillitis on inspection, after taking 1 course for the treatment of of tablet in treatment of the embodiment of the present invention 2, temperature recovery is normal, pharyngalgia, pharyngeal hyperemia transference cure, and patient fully recovers.Follow up a case by regular visits to 1 month, the state of an illness is without recurrence.

Zhang, man, 5 years old, without inducement, patient occurs that bottleneck throat swells and ache discomfort before seeking medical advice 2, pharyngeally rush blood, and lymph node swells and ache, tonsil has purulence thing, swallow process pain obvious, the same day body temperature of seeking medical advice is up to 38.7 DEG C, is children's's suppurative tonsillitis on inspection, after taking 1 course for the treatment of of tablet in treatment of the embodiment of the present invention 3, temperature recovery is normal, and pharyngalgia, pharyngeal hyperemia, lymph node swell and ache, tonsil purulence thing transference cure, and patient fully recovers.Follow up a case by regular visits to 1 month, the state of an illness is without recurrence.

All patients are all without bad reflection during medication, and experimental result shows, tablet of the present invention can be brought down a fever fast, antiinflammatory, alleviation pharyngalgia, pharyngeal hyperemia, lymph node swell and ache symptom, evident in efficacy, can safe and effective children's's suppurative tonsillitis, without recurrence after curing, be desirable medicine.

Above embodiment is only for illustrating technical conceive of the present invention and feature; its object is to allow person skilled in the art understand content of the present invention and to be implemented; can not limit the scope of the invention with this; all equivalences done according to spirit of the present invention change or modify, and all should be encompassed in protection scope of the present invention.

Claims (5)

1. treat the tablet of children's acute suppurative tonsillitis for one kind, it is characterized in that: raw material composition and the parts by weight of making described tablet are: Radix Astragali 8-10 part, Carnis Coturnicis japonicae 20-30 part, Fructus Persicae 15-20 part, Semen Tritici aestivi 45-55 part, Rhizoma Coptidis 8-10 part, Radix Scutellariae 9-12 part, Lacca 5-8 part, Radix Trichosanthis 2-5 part, Fructus Arctii 10-15 part, achillea millefolium 5-8 part, Folium Mahoniae 7-9 part, Hylocereus undatus 3-5 part, Rhizoma Curcumae 4-7 part, Pericarpium Granati 8-10 part, Herba Portulacae 15-20 part, Radix Glycyrrhizae Preparata 5-8 part, Fructus Forsythiae 10-13 part, Radix Platycodonis 8-10 part.

2. a kind of tablet for the treatment of children's acute suppurative tonsillitis as claimed in claim 1, is characterized in that: raw material composition and the parts by weight of making described tablet are: Radix Astragali 8 parts, Carnis Coturnicis japonicae 20 parts, Fructus Persicae 15 parts, Semen Tritici aestivi 45 parts, Rhizoma Coptidis 8 parts, Radix Scutellariae 9 parts, Lacca 5 parts, Radix Trichosanthis 2 parts, Fructus Arctii 10 parts, achillea millefolium 5 parts, Folium Mahoniae 7 parts, Hylocereus undatus 3 parts, Rhizoma Curcumae 4 parts, Pericarpium Granati 8 parts, Herba Portulacae 15 parts, Radix Glycyrrhizae Preparata 5 parts, Fructus Forsythiae 10 parts, Radix Platycodonis 8 parts.

3. a kind of tablet for the treatment of children's acute suppurative tonsillitis as claimed in claim 1, is characterized in that: raw material composition and the parts by weight of making described tablet are: Radix Astragali 10 parts, Carnis Coturnicis japonicae 30 parts, Fructus Persicae 20 parts, Semen Tritici aestivi 55 parts, Rhizoma Coptidis 10 parts, Radix Scutellariae 12 parts, Lacca 8 parts, Radix Trichosanthis 5 parts, Fructus Arctii 15 parts, achillea millefolium 8 parts, Folium Mahoniae 9 parts, Hylocereus undatus 5 parts, Rhizoma Curcumae 7 parts, Pericarpium Granati 10 parts, Herba Portulacae 20 parts, Radix Glycyrrhizae Preparata 8 parts, Fructus Forsythiae 13 parts, Radix Platycodonis 10 parts.

4. a kind of tablet for the treatment of children's acute suppurative tonsillitis as claimed in claim 1, is characterized in that: raw material composition and the parts by weight of making described tablet are: Radix Astragali 9 parts, Carnis Coturnicis japonicae 25 parts, Fructus Persicae 17 parts, Semen Tritici aestivi 50 parts, Rhizoma Coptidis 9 parts, Radix Scutellariae 11 parts, Lacca 7 parts, Radix Trichosanthis 3 parts, Fructus Arctii 12 parts, achillea millefolium 6 parts, Folium Mahoniae 8 parts, Hylocereus undatus 4 parts, Rhizoma Curcumae 6 parts, Pericarpium Granati 9 parts, Herba Portulacae 18 parts, Radix Glycyrrhizae Preparata 7 parts, Fructus Forsythiae 11 parts, Radix Platycodonis 9 parts.

5. a kind of preparation method for the treatment of the tablet of children's acute suppurative tonsillitis as described in Claims 1-4, is characterized in that: comprise the following steps:

(1) Carnis Coturnicis japonicae unhairing is cut into small pieces after going internal organs to clean, and adds the distilled water of its mass fraction 20 times, decocts 45 minutes at 110 DEG C, and cross 1000 order drainage screens, gained filtrate is for subsequent use, and gained Carnis Coturnicis japonicae block is boned and stayed meat for subsequent use;

(2) Semen Tritici aestivi is cleaned, and puts into steamer 120 DEG C of steaming and decoctings 20 minutes, and the Semen Tritici aestivi cooked mixes with step 1 gained quail meat to be put into 80 DEG C, baking oven and dry 60 minutes, and gained drying composite super micron mill is pulverized, and mistake 500 mesh sieves obtain powder;

(3) Radix Astragali, Rhizoma Coptidis, Radix Scutellariae, Lacca, Radix Trichosanthis, Fructus Arctii, achillea millefolium, Folium Mahoniae, Hylocereus undatus, Rhizoma Curcumae, Pericarpium Granati, Radix Glycyrrhizae Preparata, Fructus Forsythiae, Radix Platycodonis add step (1) gained filtrate and soak 1 hour, slow fire boiling 1 hour, cross 1000 order drainage screens after decocting, gained filtrate is dried in the air cool for subsequent use to room temperature;

(4) Fructus Persicae enucleation, mixes with Herba Portulacae and cleans, and add after step (3) gained filtrate is squeezed the juice and leave standstill 2 hours, cross 1000 filter screen filtration, gained filter vacuum is concentrated into the thick paste that relative density is 1.30 ± 0.02 (60 DEG C);

(5) add in thick paste obtained in step (4) by powder obtained in step (2), stirring and evenly mixing, granulate, granulate, tabletting is made sheet and is weighed the tablet of 0.5 gram and get final product.