CN104958488A - Health product for preventing or treating prostate disease and preparation method of health product - Google Patents
Health product for preventing or treating prostate disease and preparation method of health product Download PDFInfo
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- CN104958488A CN104958488A CN201510475756.6A CN201510475756A CN104958488A CN 104958488 A CN104958488 A CN 104958488A CN 201510475756 A CN201510475756 A CN 201510475756A CN 104958488 A CN104958488 A CN 104958488A
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Abstract
The invention discloses a health product for preventing or treating a prostate disease and a preparation method of the health product. The health product is prepared from the following raw materials in parts by weight: 35-65 parts of salacca edulis and 30-70 parts of carrots. The health product is prepared by the following steps: cleaning salacca edulis and carrots; shelling and denucleating the salacca edulis; and shelling the carrots, cutting into pieces, juicing and mixing evenly. The health product is nontoxic, free of side effect and obvious in action; prostatitis and benign prostatic hyperplasia can be effectively treated; and a novel selection is provided for the health product or medicine for preventing or treating the prostatitis.
Description
Technical field
The present invention relates to field of health care products, specifically a kind of prevention or the health product for the treatment of prostatosis and preparation method thereof.
Background technology
Prostate is as Semen Castaneae, and the end upward, is affixed with bladder, point down, to urogenital diaphragm, before paste pubic symphysis, after according to rectum, so when having prostatauxe, can rectal touch be done, the prostatic back side of stereognosis.The centre of prostate gland has urethra to pass, and it is suitable for reading to hold urethra, so prostate is ill, urinates first influenced.But along with the increase at age, male easily suffers from prostatosis, mainly comprise prostatic hyperplasia and prostatitis.
Prostatitis refers to prostate specific and the active chronic inflammation caused by non-specific infection, thus the whole body caused or local symptom.Harm: 1) painful, affects work and life.Due to the stimulation of inflammation, produce series of symptoms, as the position distending pains such as waist sacrum, perineum, testis, urine retention, nocturia frequency etc., make patient's dysphoria, affect work and life.2) affect sexual function, cause sexual impotence, premature ejaculation.Because disease fails to cure for a long time, various symptom and discomfort increase the weight of after intercourse, or directly affect impression and the quality of sexual life, cause a kind of pernicious stimulation to patient, gradually occur a kind of detest sense, cause the phenomenon such as sexual impotence, premature ejaculation.3) impact fertility, can cause sterile.Long-term chronic inflammatory disease, prostatic fluid composition is changed, and prostatic secretions function is affected, and then affects the liquefying time of seminal fluid, and motility of sperm declines, and can cause male sterility.4) cause chronic nephritis, even can develop into uremia.Prostatitis, as treated not in time, can cause prostatic hyperplasia, oppress bladder outlet, urine can not be emptied completely, occur residual urine.Residual urine is vegetative good culture medium, and mucous membrane of urinary bladder defense mechanism is impaired in addition, therefore very easily causes urinary tract infection as pyelonephritis etc., now as treatment is not thorough, by pyelonephritis, hydronephrosis etc., and then develops into nephritis, finally develops into uremia.5) cause endocrine disturbance, cause psychological problem.Under normal circumstances, prostate can secrete various active material.Because prostate is inflamed, endocrine disturbance, can cause neurasthenia, so that spirit occurs abnormal; Also the symptoms such as insomnia and dreamful sleep, weak dizziness, bradyphrenia, hypomnesis can be there is.6) infect spouse and cause gynecological inflammation.Prostatitis can be transmitted to wife, particularly the prostatitis that causes of some special courses of infection, and its inflammation can by sexual intercourse route infection to wife.As mycotic prostatitis, trichomonal prostatitis, gonococcal prostatitis, non-gonococcal (chlamydia, mycoplasma) prostatitis etc.7) easily infection is caused.Containing a kind of antibiotic substance in human prostate, be prostate antimicrobial factors.When prostate inflammation, this antimicrobial factors reduces, so easily cause infection.The infection that prostatitis causes can cause acute urinary retention, acute seminal vesiculitis or epididymitis, deferentitis, spermatic cord lymphadenectasis or tenderness etc., time serious, inguiodynia or renal colic can occur.8) easily tumor is suffered from.U.S.'s data in 1985 thinks that oncogene is most important factor, and virus is also the possible cause of disease.Find in the U.S.'s one group of retrospective study, exist between prostate and incidence of Gonorrhea and there is contacting of statistical significance, thus the cause of disease proposing carcinoma of prostate is relevant with viral sexually transmitted disease (STD) and chronic infection.Current research shows, containing a kind of cancer-resisting substance in normal human prostate liquid, significant to Tumor suppression.And prostate ill time this cancer-resisting substance reduce, thus easily cause tumor.
Pathology and the analysis pathology prostate of prostatic hyperplasia divide inside and outside two-layer: internal layer is periurethral mucosa and submucosal glands; Skin is body of prostate.The latter forms prostatic main body, has fibrous membrane to separate between two-layer.Prostatic hyperplasia mainly occurs in internal layer, in the body of gland interstitial of neck of bladder to seminal colliculus one section of Posterior urethral, now claims this part to be that transitional zone microscopy is visible.The prostate of hypertrophy makes neck of bladder block, and bladder is strengthened contraction make detrusor generation compensatory plumpness in little beam-like projection for being overcome cervical region resistance.Bladder cavity is intrinsic pressure to be increased, and mucous membrane of urinary bladder outwards can swell by weakness between muscle bundle, forms diverticulum obstruction at vesical neck.Continue to increase the weight of, urine will residue in bladder to some extent, and with increasing of residual urine, the wall of urinary bladder gradually thinning physiological flap valve effect that ureter lower end diagonal is formed through wall of urinary bladder muscle layer lost efficacy.Just adverse current is to ureter and renal pelvis for intravesical urine, and cause urinary tract hydrops on both sides, Renal pelvic pressure increases, and makes the atrophy of excess of the kidney matter ischemic, causes renal hypofunction finally uremia to occur.
Although Current therapeutic prostatic hyperplasia, prostatitic medicine are more, both mostly are chronic disease, if long-term prescription, can bring otherwise negative effect to patient body.If can be theoretical according to the traditional Chinese medical science " integration of edible and medicinal herbs ", a kind of determined curative effect, good mouthfeel and be convenient to industrial prostatosis dietary product be provided, will bring glad tidings for patient.
Summary of the invention
The object of the present invention is to provide health product of a kind of effective prevention or treatment prostatosis and preparation method thereof, to solve the problem proposed in above-mentioned background technology.
For achieving the above object, the invention provides following technical scheme:
Health product for prevention or treatment prostatosis, are made up of the following raw material according to weight portion: salacca edulis salak 35-65 part, Radix Dauci Sativae 30-70 part.
As the further scheme of the present invention: the health product of described prevention or treatment prostatosis, are made up of the following raw material according to weight portion: salacca edulis salak 45-55 part, Radix Dauci Sativae 45-55 part.
As the further scheme of the present invention: the health product of described prevention or treatment prostatosis, are made up of the following raw material according to weight portion: salacca edulis salak 50 parts, 50 parts, Radix Dauci Sativae.
The preparation method of health product of described prevention or treatment prostatosis, is made up of following steps: salacca edulis salak, Radix Dauci Sativae are cleaned, and salacca edulis salak is removed the peel enucleation, and Radix Dauci Sativae is removed the peel, and then stripping and slicing, squeezes the juice, and makes preparation and get final product after mixing.
As the further scheme of the present invention: described preparation is tablet, granule, capsule, pill or oral liquid.
Salacca edulis salak in the present invention, have another name called husky Singapore, it is Palmae (Palmae or Arecae) Salacca (Sa-lacca) plant, English " salak " or " snake fruit " by name, Classification system is " Salacca zalacca (Gaertner) Voss ", having another name called " Salacca edulis Reinw ", is the famous fruit in Southeast Asia.Salacca edulis salak is containing protein, carbohydrate, calcium, fat, ferrum, vitamin (B1) and vitamin (C2).Salacca edulis salak is very delicious, and taste is fresh and sweet, tasty and refreshing.The sarcocarp of salacca edulis salak is that white middle band is yellow, but to bite away be very sharp and clear sensation, and meat very the universe is hard, very sour and astringent.Salacca edulis salak has the effect of beauty treatment.Salacca edulis salak sarcocarp contains human body skin beneficiating ingredient, and it often eats as beauty treatment fruit by the local Miss of Indonesia.It is one of kind that in fruit, potassium content is the highest, and pectin content is also very abundant, very useful to human brain.
Containing abundant carotene in Radix Dauci Sativae; the free radical that one is removed blood, blood and intestinal in human body can be played; the effect of a prevention and cure of cardiovascular disease can be reached; Radix Dauci Sativae is also containing abundant sugar reducing substance simultaneously; as Quercetin, these two kinds of elements of kaempferol just can play the effect that increases coronary artery blood flow, have very large help to reduction blood fat; adrenergic synthesis can also be promoted, the effect of protection cardiovascular health.Radix Dauci Sativae is contained in abundant vitamin A, and speckle dispelling keeps the elasticity of skin.Radix Dauci Sativae also has effect of liver-benefiting eye-brightening.Lignin in Radix Dauci Sativae can improve the immunity of body, simultaneously when carotene is converted into the immunologic function that vitamin A also contributes to enhancing body, plays the effect that is eliminated cancerous cell indirectly.Radix Dauci Sativae promotes intestinal health, enhances metabolism, and promotes blood circulation, slow down aging.
Compared with prior art, the invention has the beneficial effects as follows:
The present invention is nontoxic, have no side effect, and can effectively treat prostatitis and prostatic hyperplasia, and effect obviously, for prevention or treat prostatitic health product or medicine provides a kind of selection newly.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, be clearly and completely described the technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
In the embodiment of the present invention, the health product of a kind of prevention or treatment prostatosis, are made up of the following raw material according to weight portion: salacca edulis salak 35 parts, 70 parts, Radix Dauci Sativae.
The preparation method of the health product of described prevention or treatment prostatosis, be made up of following steps: salacca edulis salak, Radix Dauci Sativae are cleaned, and salacca edulis salak is removed the peel enucleation, Radix Dauci Sativae is removed the peel, then stripping and slicing, to squeeze the juice, make tablet, granule, capsule, pill or oral liquid after mixing and get final product.
Embodiment 2
In the embodiment of the present invention, the health product of a kind of prevention or treatment prostatosis, are made up of the following raw material according to weight portion: salacca edulis salak 65 parts, 30 parts, Radix Dauci Sativae.
Preparation process as described in Example 1.
Embodiment 3
In the embodiment of the present invention, the health product of a kind of prevention or treatment prostatosis, are made up of the following raw material according to weight portion: salacca edulis salak 45 parts, 55 parts, Radix Dauci Sativae.
Preparation process as described in Example 1.
Embodiment 4
In the embodiment of the present invention, the health product of a kind of prevention or treatment prostatosis, are made up of the following raw material according to weight portion: salacca edulis salak 55 parts, 45 parts, Radix Dauci Sativae.
Preparation process as described in Example 1.
Embodiment 5
In the embodiment of the present invention, the health product of a kind of prevention or treatment prostatosis, are made up of the following raw material according to weight portion: salacca edulis salak 50 parts, 50 parts, Radix Dauci Sativae.
Preparation process as described in Example 1.
Beneficial effect of the present invention is illustrated below by way of test example.
Test example 1 the present invention is to the effect of prostatic hyperplasia
1. experiment material
1.1 laboratory animal
Kunming mouse, the quality certification number: scxk (river) 2008-24.SD rat, the quality certification number: scxk (river) 2008-24
1.2 Experimental agents and reagent
Test medicine: prepared by embodiment 5.
Test medicine grouping and dosage: high dose group of the present invention: 46.50g/ (kgd); Middle dosage group: 23.25g/ (kgd); Low dose group: 11.63g/ (kgd), is equivalent to 5 times of the clinical consumption per day of normal type 60kg people, 10 times, 20 times respectively.
Blank group: 0.9% normal saline gavages.
Aspirin: Hefei Jiu Lian pharmaceutical Co. Ltd produces, and batch number: 20110108, faces with aspirin being formulated as 60mg/ml suspension for subsequent use.
Indomethacin: Chongqing Ke Rui pharmaceutical Co. Ltd produces, and batch number: 09060l, faces with indomethacin being formulated as 2.5mg/ml suspension for subsequent use.
Dimethylbenzene: Chengdu Ke Long chemical reagent factory, lot number: 20100116.
QIANLIEKANG: Zhejiang Kang Enbei drugmaker produces, lot number: 930211.Face the suspension with QIANLIEKANG being formulated as 75mg/ml.
2. experimental technique
2.1 modeling of experimental rat prostatic hyperplasia and medications
Literature method is imitated in the modeling of prostate model, get healthy male SD rat 90, random taking-up 20 rat skin lower injection equal-volume normal saline, as solvent control group, all the other 70 whole subcutaneous injection Testosterone Propionate 3.5mg/ (kgd), successive administration 25d.Then get 10 rats at random from Testosterone Propionate group, empty stomach 12h together with normal saline group 10 rats, after 45mg/kg pentobarbital sodium injecting anesthetic, accurately take body weight, take prostate to weigh, with prostate ponderal index (body of gland weight/body weight), become large evaluation index as prostatic hyperplasia, compare with between t method of inspection group.
After determining that experimental group prostate obviously increases, experimental group 60 rats are divided into 6 groups, i.e. model group at random, estradiol group, QIANLIEKANG positive controls, the high, medium and low dosage group of the present invention.Blank group gives equal-volume normal saline, after successive administration treats 4 weeks, ditto takes empty body weight and weight of prostate, to compare between prostate ponderal index group, evaluates the therapeutical effect of medicine.
2.2 data statistics
Experimental data spss13.0 statistical software process, indices all represents with mean plus-minus standard deviation, compares and adopt t inspection between each group.
3. experimental result
3.1 the present invention are to the effect of experimental rat prostatic hyperplasia
As can be seen from experimental result, the high, medium and low dosage group of QIANLIEKANG group, test medicine all can reduce the benign prostatic hyperplasia in rats (P < 0.05) that testosterone propionate causes.Illustrate that the present invention is inhibited to prostatic hyperplasia.Experimental result is in table 1.
Table 1 the present invention is on the impact of benign prostatic hyperplasia in rats
Note: compare with model group: * * P < 0.01; * P < 0.05
4. discuss
Show by testing above, the present invention has significantly suppression and therapeutical effect to prostatic hyperplasia.
Test example 2 the present invention is on prostatitic impact
1. experiment material is as test example 1.
2. experimental technique
2.1 the present invention are to the effect of Rat Experimental chronic prostatitis
The foundation of chronic prostatitis model: get SD male rat 60,50 under strict sterilization, with amobarbital sodium intraperitoneal injection of anesthesia (100mg/kg).Anaesthetize successfully, take off median abdominal incision under aseptic condition, through abdominal cavity proposes bladder and both sides spermatic cord, exposes the prostate notopodium invested inside seminal vesicle, injects 1% carrageenin normal saline solution 0.1mL suture muscles, skin respectively.Another 10 under equal conditions row sham-operation contrast.Under guarantee conditions of water drinking, plain particles word material is fed.
Experimental technique: we select postoperative 4d according to preliminary result, i.e. inflammation peak period, 50 rats are divided at random high dose group of the present invention, middle dosage group, low dose group, every day, empirically 2.1.1 gavage gave to test medicinal liquid, positive drug group gavage gives indomethacin suspension, and chronic prostatitis model group and rats in sham-operated group fill with the distilled water of same volume.After successive administration 30d, after last administration 30min, anaesthetize with amobarbital sodium, cut open the belly and get prostatic fluid 10 μ L and put into leukocyte diluent, microscopy unit volume leukocyte count, separately gets prostatic fluid 1, smear, observe and record lecithin density, disconnected ridge is put to death rat and is got the observation of prostata tissue specimen subsequently.
2.2 data statistics
Experimental data spss13.0 statistical software process, indices all represents with mean plus-minus standard deviation, compares and adopt t inspection between each group.
3. experimental result
3.1 the present invention are to the effect of Rat Experimental chronic prostatitis
As can be seen from experimental result, after modeling, each group rat prostate liquid total white blood cells obviously raises, and lecithin density obviously reduces.Have connective tissue and smooth muscle between sham operated rats prostate gland, lumen of gland form is irregular, many pleats, and epithelial cell height differs, how in column, flat or cube.There is obvious statistical significance compared with sham-operation, show modeling success.After the administration of continuous 30 days, prostatic fluid total white blood cells and the lecithin density of the present invention's high, middle dosage group rat are obviously improved, and prostatic fluid total white blood cells is comparatively model group reduction obviously, and lecithin density is comparatively model group rising obviously.Through statistical procedures, there is statistical significance.Show that the present invention has the effect of certain treatment Rat Experimental chronic prostatitis.Experimental result is in table 2.
Table 2 the present invention is on the impact of prostatic fluid total white blood cells and lecithin density
Note: compare with Sham-operated control group: * * P<0.01; * P<0.05; Compare with model group: △ △ P<0.01; △ P<0.05.
4. discuss
Show by testing above, the present invention has good therapeutical effect to prostatitis.
In sum, the present invention can effectively treat prostatic hyperplasia and prostatitis, and effect obviously, provides a kind of selection newly for preventing or treating prostatic hyperplasia and prostatitic health product or medicine.
To those skilled in the art, obviously the invention is not restricted to the details of above-mentioned one exemplary embodiment, and when not deviating from spirit of the present invention or basic feature, the present invention can be realized in other specific forms.Therefore, no matter from which point, all should embodiment be regarded as exemplary, and be nonrestrictive, scope of the present invention is limited by claims instead of above-mentioned explanation, and all changes be therefore intended in the implication of the equivalency by dropping on claim and scope are included in the present invention.
In addition, be to be understood that, although this description is described according to embodiment, but not each embodiment only comprises an independently technical scheme, this narrating mode of description is only for clarity sake, those skilled in the art should by description integrally, and the technical scheme in each embodiment also through appropriately combined, can form other embodiments that it will be appreciated by those skilled in the art that.
Claims (5)
1. health product for prevention or treatment prostatosis, is characterized in that, be made up of the following raw material according to weight portion: salacca edulis salak 35-65 part, Radix Dauci Sativae 30-70 part.
2. the health product of prevention according to claim 1 or treatment prostatosis, is characterized in that, be made up of the following raw material according to weight portion: salacca edulis salak 45-55 part, Radix Dauci Sativae 45-55 part.
3. the health product of prevention according to claim 2 or treatment prostatosis, is characterized in that, be made up of the following raw material according to weight portion: salacca edulis salak 50 parts, 50 parts, Radix Dauci Sativae.
4., according to the preparation method of the health product of the arbitrary described prevention of claim 1-3 or treatment prostatosis, it is characterized in that, be made up of following steps: salacca edulis salak, Radix Dauci Sativae are cleaned, and salacca edulis salak is removed the peel enucleation, Radix Dauci Sativae is removed the peel, and then stripping and slicing, squeezes the juice, and makes preparation and get final product after mixing.
5. the preparation method of the health product of prevention according to claim 4 or treatment prostatosis, it is characterized in that, described preparation is tablet, granule, capsule, pill or oral liquid.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510475756.6A CN104958488A (en) | 2015-07-31 | 2015-07-31 | Health product for preventing or treating prostate disease and preparation method of health product |
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| CN201510475756.6A CN104958488A (en) | 2015-07-31 | 2015-07-31 | Health product for preventing or treating prostate disease and preparation method of health product |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106509522A (en) * | 2016-09-30 | 2017-03-22 | 广西汇智生产力促进中心有限公司 | Salak fruit vinegar beverage and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102670687B (en) * | 2011-06-01 | 2014-04-02 | 成都六木保健品科技开发有限公司 | Health care product composition or drug composition for preventing or treating prostatic diseases |
-
2015
- 2015-07-31 CN CN201510475756.6A patent/CN104958488A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102670687B (en) * | 2011-06-01 | 2014-04-02 | 成都六木保健品科技开发有限公司 | Health care product composition or drug composition for preventing or treating prostatic diseases |
Non-Patent Citations (1)
| Title |
|---|
| 李湘阳，等。: ""蛇皮果的组织培养研究"", 《中国农学通报》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106509522A (en) * | 2016-09-30 | 2017-03-22 | 广西汇智生产力促进中心有限公司 | Salak fruit vinegar beverage and preparation method thereof |
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Application publication date: 20151007 |