CN104771627B - A kind of Chinese medicine composition for treating the prolapse of uterus - Google Patents

Abstract

The present invention relates to the Chinese medicine composition of the treatment prolapse of uterus, can effectively solve the problems, such as the medication of the prolapse of uterus, its technical scheme solved is made up of the material medicine of following parts by weight meter：5 20 parts of 10 40 parts of Herba Setariae palmifoliae, 10 30 parts of the Radix Astragali, 5 15 parts of rattletop, 5 15 parts of Fructus Aurantii, 10 20 parts of the fruit of Cherokee rose, 5 15 parts of cuttlebone, 10 20 parts of aetite, 5 15 parts of dried human placenta and deer horn glue, abundant raw material of the present invention, it is cheap, component science, reasonable compatibility, support mutually, all medicines play tonifying middle-Jiao and Qi liter and carry, train the effect of member is astringent or styptic treatment for spontaneous sweating altogether, effective for treating the prolapse of uterus, good effect, drug safety, it is to treat the big innovation on prolapse of uterus medicine.

Description

A kind of traditional Chinese medicine composition for treating uterine prolapse

technical field

The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition for treating uterine prolapse.

Background technique

Uterine prolapse is referred to as Yin Ting, Yin Prolapse, etc. in traditional Chinese medicine. The cause is usually excessive birth, long labor during delivery, excessive force or improper handling, damage to the cell network; or early participation in heavy physical labor after delivery, standing and squatting for too long; or weak constitution, long-term cough, constipation, diarrhea, etc. This leads to increased abdominal pressure, which can overstretch or damage the pelvic floor muscles and fascia. The patient suffers from fatigue and prolificacy, which damages the spleen and kidneys. Insufficient spleen qi leads to subsidence of central qi, loss of kidney qi leads to loss of contraction of the meridians, failure of Chong and Ren, inability to maintain the uterus, relaxation of uterine ligaments, and loss of suspension of the uterus. Western medicine treatment is mainly based on supportive therapy, pessary or surgical treatment, and the clinical curative effect is not obvious. Therefore, the improvement and innovation of drugs for the treatment of uterine prolapse is an urgent problem to be solved at present.

Contents of the invention

In view of the above situation, in order to solve the defects of the prior art, the object of the present invention is to provide a traditional Chinese medicine composition for treating uterine prolapse, which can effectively solve the medication problem of uterine prolapse.

The technical scheme solved by the present invention is made from the following raw materials in parts by weight: 10-40 parts of bamboo head grass, 10-30 parts of astragalus, 5-15 parts of Cimicifuga, 5-15 parts of Fructus aurantium, 10-20 parts of kelp, 5-15 parts of octopus, 10-20 parts of Yu Yuliang, 5-15 parts of Ziheche and 5-20 parts of deer horn glue.

The invention has rich raw materials, low price, scientific components, reasonable compatibility and mutual support, and all the medicines have the effects of invigorating the middle, replenishing qi, improving energy, nourishing yuan and strengthening astringency, and are effectively used to treat uterine prolapse, with good curative effect and safe medication. It is a major innovation in the treatment of uterine prolapse.

detailed description

The specific implementation of the present invention will be described in further detail below in conjunction with the examples.

Example 1

When the present invention is implemented, it can be prepared from the following raw materials in parts by weight: 10 parts of bamboo head grass, 30 parts of astragalus, 5 parts of Cimicifuga, 15 parts of Citrus aurantii, 10 parts of Fructus Rosa, 15 parts of sea octopus , 10 parts of Yu Yuliang, 15 parts of Ziheche and 5 parts of antler glue.

Example 2

When the present invention is implemented, it can also be made from the following raw materials in parts by weight: 25 parts of bamboo head grass, 20 parts of astragalus, 10 parts of Cimicifuga, 10 parts of Citrus aurantii, 15 parts of Fructus Rosa, 10 parts of sea octopus 15 servings of Yu Yuliang, 10 servings of Ziheche and 12 servings of antler glue.

Example 3

When the present invention is implemented, it can also be made from the following raw materials in parts by weight: 40 parts of bamboo head grass, 10 parts of astragalus, 15 parts of Cimicifuga, 5 parts of Citrus aurantii, 20 parts of Fructus Rosa, 5 parts of sea octopus 20 parts of Yu Yuliang, 5 parts of Ziheche and 20 parts of antler glue.

Example 4

When the present invention is actually implemented, it can also be made from the following raw materials in parts by weight: 10-25 parts of bamboo head grass, 10-25 parts of astragalus, 5-10 parts of Cimicifuga, 5-10 parts of Fructus aurantium, and 10-15 parts of kelp, 5-10 parts of octopus, 10-15 parts of Yu Yuliang, 5-10 parts of Ziheche and 5-12 parts of deer horn glue.

Example 5

When the present invention is actually implemented, it can also be made from the following raw materials in parts by weight: 26-40 parts of bamboo head grass, 26-30 parts of astragalus, 11-15 parts of Cimicifuga, 11-15 parts of Citrus aurantii, and golden cherry 16-20 parts of kelp, 11-15 parts of octopus, 11-20 parts of Yu Yuliang, 11-15 parts of Zihe car and 13-20 parts of deer horn glue.

The Chinese medicine composition of the present invention can be made into various dosage forms suitable for application such as decoction, powder (powder), tablet, granule, pill, capsule, etc. according to the actual clinical needs, and the conventional method is given below The prepared decoction is as follows: first mix bamboo head grass, astragalus, cohosh, aurantium citrus, golden cherry, sea octopus, Yu Yuliang, Ziheche and antler gum, and put it into a medicine jar. Submerge in water, soak for 30-60min, decoct with strong fire until boiling, then decoct with slow fire for 20-30min, filter to get the filtrate, add water to the filter residue, decoct with strong fire until boiling, then decoct with slow fire for 20-30min, Filtrate to obtain the filtrate, combine the two filtrates, mix well and serve.

Among the components of the present invention:

Bamboo Head Grass: sweet, warm. Return the spleen channel. Yiqi solid off. It is clinically used for prolapse of the anus and uterine prolapse.

Radix Astragali: sweet, warm. Return lung, spleen channel. Invigorating qi and solidifying the surface, diuretic to support toxin, evacuation of pus, astringing sores and promoting granulation. For qi deficiency and fatigue, lack of appetite, loose stools, subsidence of middle qi, prolonged diarrhea and prolapse of the anus, bloody stool and metrorrhagia, surface deficiency and spontaneous sweating, qi deficiency and edema, carbuncle and gangrene that are difficult to burst, long-term ulceration, blood deficiency and jaundice, internal heat and quenching thirst; chronic nephritis Proteinuria, diabetes.

Radix Cimicifugae: pungent, slightly sweet, slightly cold. Return lung, spleen, stomach, large intestine channel. Release rash, clear away heat and detoxify, promote yang. For wind-heat headache, toothache, aphthous sores, sore throat, impervious measles, spotting of impotence; prolapse of the anus, prolapse of the uterus.

Fructus Aurantii: bitter, pungent, sour, warm. Return spleen, stomach warp. Regulating qi and widening the middle, stagnation and swelling. For stagnation of qi in the chest and hypochondrium, fullness and pain, inability to dissolve food accumulation, internal stagnation of phlegm and retention; gastroptosis, prolapse of the anus, and prolapse of the uterine organs.

Fructus Rosa: sour, sweet, astringent, flat. Return kidney, bladder, large intestine channel. Strengthening essence and reducing urination, astringent intestines to relieve diarrhea. Used for nocturnal emission and spermatorrhea, enuresis and frequent urination, metrorrhagia and vaginal discharge, chronic diarrhea and dysentery.

Sea octopus: salty, astringent, warm. Return spleen, kidney channel. Astringent to stop bleeding, astringent essence to stop belt, antacid, astringent sores. For stomachache, acid regurgitation, vomiting blood and epistaxis, metrorrhagia and hematochezia, nocturnal emission and spermatorrhea, red and white discharge; ulcer disease. External treatment injury bleeding, sores with pus.

Yu Yuliang: sweet, astringent, slightly cold. Return stomach, large intestine channel. Astringent intestinal antidiarrheal, astringent to stop bleeding. For chronic diarrhea, chronic dysentery, metrorrhagia, leucorrhea.

Ziheche: sweet, salty, warm. Guixin, lung, kidney channel. Warming the kidney and tonifying essence, nourishing qi and blood. It is used for fatigue and emaciation, bone steaming and night sweats, cough and asthma, shortness of breath due to lack of food, impotence and nocturnal emission, infertility and less breast milk.

Deer horn glue: sweet, salty, warm. Return kidney, Liver Channel. Warming and nourishing liver and kidney, benefiting essence and nourishing blood. It is used for impotence and spermatorrhea, soreness and coldness of the waist and knees, fatigue and emaciation, metrorrhagia, hematuria, hematuria, and gangrene swelling and pain.

The traditional Chinese medicine composition for treating uterine prolapse of the present invention is developed on the basis of the basic theory of traditional Chinese medicine, and has the functions of invigorating the middle, replenishing qi, promoting and improving, and nourishing essence and strengthening astringency. In the prescription, Astragalus membranaceus and Bambusa invigorate qi and lift; Cimicifugae promotes yang; Fructus aurantium regulates qi, widens and moderates stagnation and relieves swelling; Golden cherry fruit, sea octopus, and Yu Yu grain converge and solidify; Ziheche and deer horn glue nourish kidney and fill Refined. The whole prescription nourishes the kidney and strengthens the body, nourishes the qi, and uses the comprehensive effects of various traditional Chinese medicines to treat uterine prolapse. It is non-toxic and harmless to the human body, has good curative effect, and is safe to use. It has been fully proved by clinical trials. The relevant clinical trial data are as follows:

The Chinese medicine composition of the present invention takes decoction as an example,

1. General information

120 patients were randomly divided into treatment group and control group. The treatment group included 60 cases, aged 35 to 65 years, with an average age of (48.38±12.71) years; the number of pregnancies was 1 to 4, with an average of (1.67±0.42) times; the course of disease was 2 to 14 years, with an average of (7.5±2.16) years; uterine prolapse There were 18 cases with degree I and 12 cases with degree II. 60 cases in the control group, aged 32 to 67 years, with an average of (46.12±10.89) years; pregnancy times 1 to 3, with an average of (1.75±0.52) times; course of disease 2 to 15 years, with an average of (8.2±2.73) years; uterine prolapse There were 17 cases with degree I and 13 cases with degree II. The data of the two groups were statistically processed, and there was no significant difference in age and condition (P>0.05), which were comparable.

2. Case inclusion criteria

All the selected patients were diagnosed for the first time without formal treatment; accompanied by anterior or posterior vaginal wall prolapse; uterine prolapse accompanied by serious heart, brain, kidney and other serious complications were excluded; uterine prolapse accompanied by pelvic floor Muscular atrophy; uterine prolapse with severe cervical ulcer, infection and suppuration, and congenital elongation of the cervix.

3. Treatment plan

Treatment group: use Chinese medicine composition of the present invention to make decoction, each time sooner or later, warm clothes, each 200-300ml.

Control group: adopt supportive therapy, including strengthening nutrition, arrange rest and work reasonably, avoid heavy physical labor, avoid long-term standing or squatting, breath-holding and other actions that increase abdominal pressure, keep stool unobstructed, keep perineum clean, and actively perform gymnastics To exercise the pelvic floor muscles and abdominal wall muscles. For example, instruct the patient to perform anal contraction exercises, that is, anal contraction and loosening movements, twice a day, 10 minutes each time; perform knee-chest position exercises: empty the urine, loosen the belt, relax the whole body, kneel on the hard board bed, head Put on the bed, face turned to one side, arms slightly bent forward, hips raised and thighs at right angles. 1 time in the morning and evening, 10 minutes each time.

The course of treatment for both the treatment group and the control group was 30 days, and the curative effect was counted after one course of treatment.

4. Evaluating Criteria for Efficacy

Cure: Symptoms disappear, and the position of the cervix returns to above the level of the ischial spine;

Significantly effective: Symptoms disappear, the uterus is retracted into the vagina, and the external opening of the cervix is close to the level of the ischial spine;

Effective: The symptoms are better than before, and the uterus returns to the vagina slightly improved;

Ineffective: The symptoms did not improve, and the situation of the uterus returning to the vagina did not improve compared with before treatment.

5. Statistical processing

Statistical software SPSS13.0 was used, the x2 test was used for the count data, and the Ridit test was used for the rank data.

According to the above-mentioned treatment plan, oral Chinese medicine composition decoction that the present invention provides, as can be seen from Table 1, 26 examples of treatment group recovered from illness, 18 examples were markedly effective, 14 examples were effective, 2 examples were invalid, and the total effective rate was 96.66%; In the group, 10 cases were cured, 12 cases were markedly effective, 20 cases were effective, and 18 cases were ineffective. The total effective rate was 70%. Compared with the control group, there are significant statistical differences in recovery, ineffectiveness and total effective rate between the treatment group and the control group.

Table 1 Comparison of clinical efficacy between the two groups

Compared with the control group, *P＜0.05, **P＜0.01

The Chinese medicine composition of the present invention has been made into other dosage forms, and the same or similar results have been obtained in the experiment, so they are not listed one by one to prevent repeated descriptions. Moreover, what the application claims is the Chinese medicine composition (combined invention), and It does not depend on the dosage form or the preparation method. Therefore, any medicine made from the traditional Chinese medicine composition of the application and used for the treatment of uterine prolapse belongs to the scope of protection of the application.

6 Conclusion

The composition of the invention is scientific, the raw materials are abundant, the price is low, the compatibility is reasonable, and mutual support is achieved. The effective rate is as high as 96%, which is a major innovation in the treatment of uterine prolapse and has practical clinical significance.

Claims (7)

1. a kind of Chinese medicine composition for treating the prolapse of uterus, it is characterised in that be made up of the material medicine of following parts by weight meter： Herba Setariae palmifoliae 10-40 parts, Radix Astragali 10-30 parts, rattletop 5-15 parts, Fructus Aurantii 5-15 parts, fruit of Cherokee rose 10-20 parts, cuttlebone 5-15 parts, Yu Surplus grain 10-20 parts, dried human placenta 5-15 parts and deer horn glue 5-20 parts.

2. the Chinese medicine composition of the treatment prolapse of uterus according to claim 1, it is characterised in that by following parts by weight meter Material medicine be made：10 parts of Herba Setariae palmifoliae, 30 parts of the Radix Astragali, 5 parts of rattletop, 15 parts of Fructus Aurantii, 10 parts of the fruit of Cherokee rose, 15 parts of cuttlebone, Yu 5 parts of 10 parts of surplus grain, 15 parts of dried human placenta and deer horn glue.

3. the Chinese medicine composition of the treatment prolapse of uterus according to claim 1, it is characterised in that by following parts by weight meter Material medicine be made：25 parts of Herba Setariae palmifoliae, 20 parts of the Radix Astragali, 10 parts of rattletop, 10 parts of Fructus Aurantii, 15 parts of the fruit of Cherokee rose, 10 parts of cuttlebone, Yu 12 parts of 15 parts of surplus grain, 10 parts of dried human placenta and deer horn glue.

4. the Chinese medicine composition of the treatment prolapse of uterus according to claim 1, it is characterised in that by following parts by weight meter Material medicine be made：40 parts of Herba Setariae palmifoliae, 10 parts of the Radix Astragali, 15 parts of rattletop, 5 parts of Fructus Aurantii, 20 parts of the fruit of Cherokee rose, 5 parts of cuttlebone, Yu Yu 20 parts of 20 parts of grain, 5 parts of dried human placenta and deer horn glue.

5. the Chinese medicine composition of the treatment prolapse of uterus according to claim 1, it is characterised in that by following parts by weight meter Material medicine be made：Herba Setariae palmifoliae 10-25 parts, Radix Astragali 10-25 parts, rattletop 5-10 parts, Fructus Aurantii 5-10 parts, fruit of Cherokee rose 10-15 parts, Cuttlebone 5-10 parts, aetite 10-15 parts, dried human placenta 5-10 parts and deer horn glue 5-12 parts.

6. the Chinese medicine composition of the treatment prolapse of uterus according to claim 1, it is characterised in that by following parts by weight meter Material medicine be made：Herba Setariae palmifoliae 26-40 parts, Radix Astragali 26-30 parts, rattletop 11-15 parts, Fructus Aurantii 11-15 parts, fruit of Cherokee rose 16-20 Part, cuttlebone 11-15 parts, aetite 11-20 parts, dried human placenta 11-15 parts and deer horn glue 13-20 parts.

7. described in claim 1 or any one of 2-6 treatment the prolapse of uterus Chinese medicine composition, routinely preparation method soup is made Agent, pulvis, tablet, granule, pill, one kind of capsule.