CN103393797A - Traditional Chinese medicine composition for treating dysmenorrhea of women and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating dysmenorrhea of women and preparation method thereof Download PDFInfo
- Publication number
- CN103393797A CN103393797A CN2013103479704A CN201310347970A CN103393797A CN 103393797 A CN103393797 A CN 103393797A CN 2013103479704 A CN2013103479704 A CN 2013103479704A CN 201310347970 A CN201310347970 A CN 201310347970A CN 103393797 A CN103393797 A CN 103393797A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- medicine composition
- radix
- traditional chinese
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 title claims abstract description 63
- 239000000203 mixture Substances 0.000 title claims abstract description 39
- 238000002360 preparation method Methods 0.000 title claims abstract description 20
- 208000005171 Dysmenorrhea Diseases 0.000 title abstract description 9
- 206010013935 Dysmenorrhoea Diseases 0.000 title abstract description 9
- 241000221635 Cladonia Species 0.000 claims abstract description 18
- 235000004347 Perilla Nutrition 0.000 claims abstract description 4
- 229940079593 drug Drugs 0.000 claims description 25
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 20
- 241000628997 Flos Species 0.000 claims description 17
- 241001535076 Haplopteris fudzinoi Species 0.000 claims description 17
- 210000000582 semen Anatomy 0.000 claims description 9
- 239000000706 filtrate Substances 0.000 claims description 8
- 238000007493 shaping process Methods 0.000 claims description 5
- 239000002671 adjuvant Substances 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 3
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 3
- 241000545442 Radix Species 0.000 claims description 2
- 241000229722 Perilla <angiosperm> Species 0.000 claims 2
- 208000002193 Pain Diseases 0.000 abstract description 17
- 239000008280 blood Substances 0.000 abstract description 15
- 210000004369 blood Anatomy 0.000 abstract description 14
- 230000000694 effects Effects 0.000 abstract description 14
- 230000006870 function Effects 0.000 abstract description 13
- 230000001105 regulatory effect Effects 0.000 abstract description 9
- 230000005906 menstruation Effects 0.000 abstract description 7
- 230000003213 activating effect Effects 0.000 abstract description 3
- WUKWITHWXAAZEY-UHFFFAOYSA-L calcium difluoride Chemical compound [F-].[F-].[Ca+2] WUKWITHWXAAZEY-UHFFFAOYSA-L 0.000 abstract description 3
- 238000010792 warming Methods 0.000 abstract description 3
- 241000445986 Embelia parviflora Species 0.000 abstract description 2
- 244000124853 Perilla frutescens Species 0.000 abstract description 2
- 239000010436 fluorite Substances 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 235000000100 Hibiscus rosa sinensis Nutrition 0.000 abstract 1
- 241001349804 Juncus alpinoarticulatus Species 0.000 abstract 1
- 240000008254 Rosa chinensis Species 0.000 abstract 1
- 235000000664 Rosa chinensis Nutrition 0.000 abstract 1
- 235000016785 Rosa della China Nutrition 0.000 abstract 1
- 230000007012 clinical effect Effects 0.000 abstract 1
- 239000008183 oral pharmaceutical preparation Substances 0.000 abstract 1
- 230000003014 reinforcing effect Effects 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 239000002775 capsule Substances 0.000 description 18
- 239000000796 flavoring agent Substances 0.000 description 13
- 235000019634 flavors Nutrition 0.000 description 13
- 210000004185 liver Anatomy 0.000 description 13
- 241000209020 Cornus Species 0.000 description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 12
- 210000003734 kidney Anatomy 0.000 description 12
- 230000007812 deficiency Effects 0.000 description 8
- 239000008187 granular material Substances 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 229920002472 Starch Polymers 0.000 description 6
- 238000001035 drying Methods 0.000 description 6
- 238000005469 granulation Methods 0.000 description 6
- 230000003179 granulation Effects 0.000 description 6
- 239000008107 starch Substances 0.000 description 6
- 235000019698 starch Nutrition 0.000 description 6
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 230000001225 therapeutic effect Effects 0.000 description 5
- 208000019255 Menstrual disease Diseases 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 210000000988 bone and bone Anatomy 0.000 description 4
- 241000411851 herbal medicine Species 0.000 description 4
- 210000000952 spleen Anatomy 0.000 description 4
- 208000011580 syndromic disease Diseases 0.000 description 4
- 208000004998 Abdominal Pain Diseases 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 206010047700 Vomiting Diseases 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 230000027758 ovulation cycle Effects 0.000 description 3
- 239000006187 pill Substances 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- 210000004291 uterus Anatomy 0.000 description 3
- 208000006820 Arthralgia Diseases 0.000 description 2
- 208000002881 Colic Diseases 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 208000000059 Dyspnea Diseases 0.000 description 2
- 206010013975 Dyspnoeas Diseases 0.000 description 2
- 206010033557 Palpitations Diseases 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 206010003549 asthenia Diseases 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 201000006549 dyspepsia Diseases 0.000 description 2
- 201000001881 impotence Diseases 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 230000027939 micturition Effects 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 231100000915 pathological change Toxicity 0.000 description 2
- 230000036285 pathological change Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000004575 stone Substances 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 239000003826 tablet Substances 0.000 description 2
- 230000008673 vomiting Effects 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 201000000736 Amenorrhea Diseases 0.000 description 1
- 206010001928 Amenorrhoea Diseases 0.000 description 1
- 241000965254 Apostichopus japonicus Species 0.000 description 1
- 241000133570 Berberidaceae Species 0.000 description 1
- 208000010392 Bone Fractures Diseases 0.000 description 1
- 241000345998 Calamus manan Species 0.000 description 1
- 244000080208 Canella winterana Species 0.000 description 1
- 235000008499 Canella winterana Nutrition 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 241000282994 Cervidae Species 0.000 description 1
- 241000283026 Cervus elaphus Species 0.000 description 1
- 241000283007 Cervus nippon Species 0.000 description 1
- 241000221641 Cladoniaceae Species 0.000 description 1
- 206010009866 Cold sweat Diseases 0.000 description 1
- 241001550206 Colla Species 0.000 description 1
- 241000123586 Dipsacaceae Species 0.000 description 1
- 241001362421 Epimedium brevicornu Species 0.000 description 1
- 208000010228 Erectile Dysfunction Diseases 0.000 description 1
- 206010017076 Fracture Diseases 0.000 description 1
- 206010019468 Hemiplegia Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010021118 Hypotonia Diseases 0.000 description 1
- 206010021639 Incontinence Diseases 0.000 description 1
- 206010024453 Ligament sprain Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 208000019695 Migraine disease Diseases 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 235000014676 Phragmites communis Nutrition 0.000 description 1
- 206010067171 Regurgitation Diseases 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 208000010040 Sprains and Strains Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 206010047601 Vitamin B1 deficiency Diseases 0.000 description 1
- 241001148807 Vittarioideae Species 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 231100000540 amenorrhea Toxicity 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 208000002894 beriberi Diseases 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 150000001669 calcium Chemical class 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000002498 deadly effect Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 239000000412 dendrimer Substances 0.000 description 1
- 229920000736 dendritic polymer Polymers 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 208000024756 faint Diseases 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 208000017561 flaccidity Diseases 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 210000004392 genitalia Anatomy 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 208000000509 infertility Diseases 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 231100000535 infertility Toxicity 0.000 description 1
- 208000021267 infertility disease Diseases 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 210000002414 leg Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 230000003821 menstrual periods Effects 0.000 description 1
- 206010027599 migraine Diseases 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 235000012950 rattan cane Nutrition 0.000 description 1
- 230000000552 rheumatic effect Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 239000002893 slag Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 206010042772 syncope Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine composition for treating dysmenorrhea of women and a preparation method thereof. The traditional Chinese medicine composition is prepared from 25-40 parts of China rose, 25-40 parts of Chinese alpine rush, 25-40 parts of perilla stem, 10-20 parts of cornu cervi degelatinatum, 10-20 parts of embelia parviflora, 10-20 parts of cladonia alpestris, 6-13 parts of root of dwarf burnet and 5-11 parts of fluorite. The traditional Chinese medicine composition can be prepared into any clinically acceptable oral pharmaceutical preparation according to the conventional traditional Chinese medicine preparation method. The traditional Chinese medicine composition has the functions of regulating qi for activating stagnancy and dispersing blood stasis, warming channels to remove cold and stop pain, and reinforcing qi and nourishing blood for regulating menstruation. Clinical effects show that the traditional Chinese medicine composition has definite and reliable effects on dysmenorrhea of women, treats both symptoms and causes, is safe in clinical application, and does not have any toxic or side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine composition for the treatment of menalgia and preparation method thereof, belong to the treatment by Chinese herbs field of menalgia.
Background technology
Dysmenorrhea refers to that periodically lower abdomen pain appears in the women in menstrual period or before and after row, and even pain connects waist.Divide two kinds of constitutional and Secondary cases, constitutional is agenosomia official pathological changes, is generally the Unmarried woman, and Secondary cases causes for genitals's pathological changes.The cause of disease is how relevant with endocrine factors, uterine factors and inherited genetic factors.Dysmenorrhea is followed the menstrual cycle outbreak, and severe patient is often accompanied nausea and vomiting, dripping cold sweat, deadly cold hand and foot, even faints, and has a strong impact on patient's work and life.
Dysmenorrhea belongs to the traditional Chinese medical science " abdominal pain during menstruation ", causes that the reason of dysmenorrhea is more complicated, treats more thornyly, and some traditional Chinese medical science scholars think and belong to one of TCM Gynecology three large difficult diseases.Menopathy is relevant with renal function, and also is correlated with in spleen, liver, QI and blood, chong channel, conception vessel, uterus." traditional Chinese medical science thinks that the reason that dysmenorrhea occurs mainly contains two kinds, the one, deficiency syndrome, i.e. " Rong Ze pain ", because deficient qi and blood or deficiency of both the liver and kidney cause, this class people should note at ordinary times adjusting and mends, benefiting qi and nourishing blood or nourishing the liver and kidney.The 2nd, excess syndrome, i.e. " stagnation of QI and blood may bring about pain ", and because QI-blood circulation does not freely cause, this class people silt pain relieving of should dispelling.Pathogenesis is mainly blockage of main and collateral channels.
At present, the Chinese patent medicine that is used for the treatment of menalgia all in various degree exist slow, the defect such as curative effect is remarkable not that takes effect, have much room for improvement.
Summary of the invention
That technical problem to be solved by this invention is that overcome existing treatment menalgia existing takes effect is slow, curative effect not significantly, the defect such as toxic and side effects is large, the Chinese medicine composition of the treatment menalgia that provide a kind of instant effect, determined curative effect, has no side effect;
Another technical problem to be solved by this invention is to provide a kind of method for preparing above-mentioned Chinese medicine composition.
Above-mentioned technical problem to be solved by this invention is achieved through the following technical solutions:
A kind of Chinese medicine composition for the treatment of menalgia, comprise that each component of following weight portion forms: Flos Rosae Chinensis, Vittaria fudzinoi Mak., Caulis Perillae, Cornu Cervi Degelatinatum, Radix seu Caulis Embeliae Parviflorae, Cladonia alpestris (L.) Rabenh., Radix Sanguisorbae Filiformis, Fluoritum.
Preferably, the weight portion of each component is: Flos Rosae Chinensis 25-40 part, Vittaria fudzinoi Mak. 25-40 part, Caulis Perillae 25-40 part, Cornu Cervi Degelatinatum 10-20 part, Radix seu Caulis Embeliae Parviflorae 10-20 part, Cladonia alpestris (L.) Rabenh. 10-20 part, Radix Sanguisorbae Filiformis 6-13 part, Fluoritum 5-11 part.
Preferred, the weight portion of each component is: Flos Rosae Chinensis 25-35 part, Vittaria fudzinoi Mak. 25-35 part, Caulis Perillae 25-35 part, Cornu Cervi Degelatinatum 10-15 part, Radix seu Caulis Embeliae Parviflorae 10-15 part, Cladonia alpestris (L.) Rabenh. 10-15 part, Radix Sanguisorbae Filiformis 6-11 part, Fluoritum 5-9 part.
Most preferred, the weight portion of each component is: 30 parts of Flos Rosae Chinensiss, 30 parts of Vittaria fudzinoi Mak.s, 30 parts of Caulis Perillaes, 13 parts of Cornu Cervi Degelatinatums, 13 parts of Radix seu Caulis Embeliae Parviflorae, 13 parts of Cladonia alpestris (L.) Rabenh.s, 9 parts of Radix Sanguisorbae Filiformis, 7 parts of Fluoritum.
Flos Rosae Chinensis: the different name Fols Rosae, month in and month out the flower etc.Nature and flavor: sweet in the mouth, warm in nature.Return Liver Channel.Function cures mainly: promoting blood flow to regulate menstruation, subduing swelling and detoxicating.The treatment menoxenia, menalgia, osteopatia sprain, blood stasis swells and ache, ulcer sore pain.
Vittaria fudzinoi Mak.: different name Herba Poae Sphondylodis.Herb for the flat rib Herba Vittariae Flexuosae of Vittariaceae plant.The four seasons can adopt, and clean using fresh herb or dry.Nature and flavor: micro-hardship, tepor, nontoxic.Function cures mainly: regulate the flow of vital energy, invigorate blood circulation, pain relieving.The treating the liver gastric qi, bones and muscles pain.
Caulis Perillae: be the stem of labiate wrinkle Folium Perillae, sharp Folium Perillae etc.Concoct: remove impurity, dry, or take advantage of fresh slices, dry.Nature and flavor: Xin Gan, tepor.Return lung, spleen channel.Function cures mainly: regulates the flow of vital energy, and Shu Yu, pain relieving, antiabortive.Control the stagnation of QI, dyspepsia, the chest and diaphragm painful abdominal mass is vexed, epigastric pain, nausea discord.
Cornu Cervi Degelatinatum: for the angle of animal in deer family Cervus nippon Temminck or Cervus elaphus linnaeus boils remaining bone slag after Colla cornus cervi.Nature and flavor: salty, temperature.Return liver, kidney channel.Function cures mainly: tonify deficiency is supporing yang.Control insufficiency of kidney-YANG, Deficiency and coldness of spleen and stomach, vomiting, lack of appetite and vomiting, metrostaxis, deficiency-cold of uterus.
Radix seu Caulis Embeliae Parviflorae: be root or the rattan of Myrsinacea plant Embelia parviflora Wall.Gather: can adopt the whole year, cleans, and section, dry.Nature and flavor: bitterness, temperature.Function cures mainly: promoting blood circulation to remove blood stasis, replenishing kidney, strengthening waist.Control menoxenia, amenorrhea, anemia, traumatic injury, fracture.
Cladonia alpestris (L.) Rabenh.: be the dendrimer of Cladoniaceae plant passeris montani saturati Herba Cladoniae rangiferinae.Nature and flavor: lightly seasoned, property is put down.Return liver, stomach warp.Function cures mainly: suppressing the hyperactive liver, stomach invigorating, regulating menstruation, hemostasis.Control: control vascular hypertension, have a dizzy spell, migraine, order disease, asthenia, epistaxis, leucorrhea, menoxenia.
Radix Sanguisorbae Filiformis: different name Stichopus japonicus, five female Na Bao (" Yunnan Chinese herbal medicine ").Root for the short Radix Sanguisorbae of rosaceous plant.Gather: autumn, winter excavate.Dry.Nature and flavor: " Yunnan Chinese herbal medicine ": " suffering, temperature." function cures mainly: 1. " Yunnan Chinese herbal medicine ": " tonifying blood and regulating menstruation.Control menoxenia, infertility." 2. " choosing of Yunnan Chinese herbal medicine ": " controls dysmenorrhea.″
Fluoritum: be the Ore of halogenide class mineral fluorite, main fluorinated calcium (CaF2).After excavating, except roguing stone.Concoct: Fluoritum, except roguing stone, is pounded into fragment.Nature and flavor: sweet, temperature.GUIXIN, Liver Channel.Function cures mainly: relieving palpitation, calm the nerves, and lowering the adverse flow of QI, warm uterus.Control the asthenia palpitation with fear, cough with dyspnea, women's sea of blood deficiency and coldness is infertile.
Chinese medicine composition of the present invention is based on the inventor to the pathogenetic research of the deep layer of menalgia and Therapeutic Principle thereof, simultaneously according to inventor clinical experience and pharmaceutical research achievement for many years, filter out the regulating qi-flowing for activating stagnancy blood stasis dispelling, the dispelling cold by warming the meridian pain relieving, the crude drug of benefiting QI and nourishing blood regulating menstruation, form according to certain weight proportion prescription.
While in above-mentioned Chinese medicine composition, further adding the raw material of following weight portion, has the effect of better treatment menalgia: Semen Trigonellae 4-8 part, Radix Linderae 4-8 part, Radix Dipsaci 3-7 part, Herba Epimedii 3-7 part; Preferably, the weight portion of each raw material is: 6 parts of Semen Trigonellae, 6 parts of the Radixs Linderae, 5 parts of Radix Dipsacis, 5 parts of Herba Epimedii.
Semen Trigonellae: the bitter bean of different name, reed bar, Hu Ba etc.Seed for the leguminous plant Semen Trigonellae.Nature and flavor: hardship, temperature.Return kidney, Liver Channel.Function is with curing mainly: kidney-replenishing, dispelling cold and dampness.Control colic of cold type, abdomen side of body distension, the disturbance of lower legs due to pathogenic cold and dampness, the soreness of waist of suffering from a deficiency of the kidney, sexual impotence.
The Radix Linderae: be the dried root of the canella Radix Linderae.Nature and flavor: suffering, temperature.Return spleen, lung, kidney, urinary bladder channel.Function cures mainly: pleasant, and dissipating depression of QI, cold expelling, pain relieving.Control the QI rising in reverse order abdominal distention, dyspepsia does not disappear, food is told in regurgitation, colic of cold type, beriberi, frequent micturition.
Radix Dipsaci: be the root of Dipsacaceae plant Radix Dipsaci or Radix Dipsaci.Nature and flavor: toil, tepor.Return Liver Channel, kidney channel.Function cures mainly: invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating.Control aching pain in waist and back, the podomere flaccidity syndrome and arthralgia syndrome, fall flutter wound, damage muscle folding bone, red, metrorrhagia is leaked in fetal movement, seminal emission, leukorrhagia, carbuncle skin ulcer are swollen.
Herba Epimedii: be the stem and leaf of Berberidaceae plant Herba Epimedii, arrow leaf Herba Epimedii, Epimedium brevicornum.Nature and flavor: Xin Gan, temperature.Return liver, kidney channel.Function cures mainly: kidney invigorating and YANG supporting, expelling wind and removing dampness.Control impotence and seminal emission, cold caused by deficiency is sterile, the frequent micturition incontinence, and dyspnea and cough due to deficiency of the kidney, soreness of the waist and knees, rheumatic arthralgia, hemiplegia, extremity are meciless.
In side of the present invention, each medicine compatibility is played the regulating qi-flowing for activating stagnancy blood stasis dispelling together altogether, the dispelling cold by warming the meridian pain relieving, the effect of benefiting QI and nourishing blood regulating menstruation, Chinese medicine composition of the present invention is for the menalgia treating both the principal and secondary aspects of a disease, the clinical observation on the therapeutic effect confirmation, Chinese medicine composition of the present invention is reliable, true for the menalgia determined curative effect.Chinese medicine composition of the present invention is nontoxic, and is safe and reliable, after taking, has no adverse reaction, clinical use safety.
The crude drug of respectively distinguishing the flavor of that the present invention is used can be bought and obtain at pharmacy.
Medicine activity component of the present invention can add various adjuvants required while preparing different dosage form, such as disintegrating agent, lubricant, adhesive etc., method of Chinese medicinal with routine is prepared into any suitable clinical oral administration preparation, and described oral formulations can be pill, powder, granule, capsule, tablet, oral liquid, drop pill etc.
A kind of preparation method of Chinese medicine composition of the present invention: after each crude drug of the present invention is taken by described weight portion proportioning, pulverize, sieve (can be for example the 80-300 mesh sieve), obtain.Certainly, after also each crude drug can being pulverized, add the required adjuvant of preparations shaping or excipient, according to conventional method, be prepared into capsule, tablet or pill.
The another kind of preparation method of Chinese medicine composition of the present invention: take each crude drug by described weight portion; Each crude drug water is decocted, merge decoction liquor, filter, filtrate is condensed into clear paste, adds adjuvant or the excipient of preparations shaping, and preparations shaping, obtain.
The usage of Chinese medicine composition of the present invention and consumption: dosage of the present invention depends on the factors such as concrete dosage form, patient's age, health status.As guidance: usage and dosage: capsule, each capsule content 0.3 gram crude drug, each oral 1 to 3,2 times on the one, 7 days is a course for the treatment of.
The specific embodiment
Below in conjunction with specific embodiment, further describe the present invention; these embodiment are only exemplary; what those skilled in the art should understand that is; lower without departing from the spirit and scope of the present invention, can modify or replace details and the form of technical solution of the present invention, but these modifications and replacement all fall within the scope of protection of the present invention.
The preparation of embodiment 1 capsule
By following weight, take each crude drug (unit: g): Flos Rosae Chinensis 25, Vittaria fudzinoi Mak. 25, Caulis Perillae 25, Cornu Cervi Degelatinatum 10, Radix seu Caulis Embeliae Parviflorae 10, Cladonia alpestris (L.) Rabenh. 10, Radix Sanguisorbae Filiformis 6, Fluoritum 5; Above-mentioned each crude drug is decocted with water to secondary, add for the first time 4 times of weight of water, decocted 2 hours, add for the second time 5 times of weight of water, decocted 1.5 hours; Decoction liquor is merged, filter, it is 1.17-1.19(60 ℃ that filtrate is concentrated into relative density) clear paste; Merge clear paste twice, add appropriate amount of starch, mix, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, obtain.
The preparation of embodiment 2 capsules
By following weight, take each crude drug (unit: g): Flos Rosae Chinensis 40, Vittaria fudzinoi Mak. 40, Caulis Perillae 40, Cornu Cervi Degelatinatum 20, Radix seu Caulis Embeliae Parviflorae 20, Cladonia alpestris (L.) Rabenh. 20, Radix Sanguisorbae Filiformis 13, Fluoritum 11; Above-mentioned each crude drug is decocted with water to secondary, add for the first time 6 times of weight of water, decocted 2 hours, add for the second time 4 times of weight of water, decocted 1.5 hours; Decoction liquor is merged, filter, it is 1.17-1.19(60 ℃ that filtrate is concentrated into relative density) clear paste; Merge clear paste twice, add appropriate amount of starch, mix, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, obtain.
The preparation of embodiment 3 capsules
By following weight, take each crude drug (unit: g): Flos Rosae Chinensis 30, Vittaria fudzinoi Mak. 30, Caulis Perillae 30, Cornu Cervi Degelatinatum 13, Radix seu Caulis Embeliae Parviflorae 13, Cladonia alpestris (L.) Rabenh. 13, Radix Sanguisorbae Filiformis 9, Fluoritum 7; Above-mentioned each crude drug is decocted with water to secondary, add for the first time 4 times of weight of water, decocted 2 hours, add for the second time 5 times of weight of water, decocted 1.5 hours; Decoction liquor is merged, filter, it is 1.30-1.35(55 ℃ that filtrate is concentrated into relative density) clear paste; Merge clear paste twice, add appropriate amount of starch, mix, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, obtain.
The preparation of embodiment 4 capsules
By following weight, take each crude drug (unit: g): Flos Rosae Chinensis 25, Vittaria fudzinoi Mak. 25, Caulis Perillae 25, Cornu Cervi Degelatinatum 10, Radix seu Caulis Embeliae Parviflorae 10, Cladonia alpestris (L.) Rabenh. 10, Radix Sanguisorbae Filiformis 6, Fluoritum 5, Semen Trigonellae 4, the Radix Linderae 4, Radix Dipsaci 3, Herba Epimedii 3; Above-mentioned each crude drug is decocted with water to secondary, add for the first time 4 times of weight of water, decocted 2 hours, add for the second time 5 times of weight of water, decocted 1.5 hours; Decoction liquor is merged, filter, it is 1.30-1.35(55 ℃ that filtrate is concentrated into relative density) clear paste; Merge clear paste twice, add appropriate amount of starch, mix, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, obtain.
The preparation of embodiment 5 capsules
By following weight, take each crude drug (unit: g): Flos Rosae Chinensis 40, Vittaria fudzinoi Mak. 40, Caulis Perillae 40, Cornu Cervi Degelatinatum 20, Radix seu Caulis Embeliae Parviflorae 20, Cladonia alpestris (L.) Rabenh. 20, Radix Sanguisorbae Filiformis 13, Fluoritum 11, Semen Trigonellae 8, the Radix Linderae 8, Radix Dipsaci 7, Herba Epimedii 7; Above-mentioned each crude drug is decocted with water to secondary, add for the first time 6 times of weight of water, decocted 2 hours, add for the second time 4 times of weight of water, decocted 1.5 hours; Decoction liquor is merged, filter, it is 1.17-1.19(60 ℃ that filtrate is concentrated into relative density) clear paste; Merge clear paste twice, add appropriate amount of starch, mix, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, obtain.
The preparation of embodiment 6 capsules
By following weight, take each crude drug (unit: g): Flos Rosae Chinensis 30, Vittaria fudzinoi Mak. 30, Caulis Perillae 30, Cornu Cervi Degelatinatum 13, Radix seu Caulis Embeliae Parviflorae 13, Cladonia alpestris (L.) Rabenh. 13, Radix Sanguisorbae Filiformis 9, Fluoritum 7, Semen Trigonellae 6, the Radix Linderae 6, Radix Dipsaci 5, Herba Epimedii 5; Above-mentioned each crude drug is decocted with water to secondary, add for the first time 6 times of weight of water, decocted 2 hours, add for the second time 4 times of weight of water, decocted 1.5 hours; Decoction liquor is merged, filter, it is 1.17-1.19(60 ℃ that filtrate is concentrated into relative density) clear paste; Merge clear paste twice, add appropriate amount of starch, mix, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, obtain.
The clinical observation on the therapeutic effect test of test example 1 traditional Chinese medicine composition for treating menalgia of the present invention
One, physical data: 120 routine patients all meet the clinical criteria of menalgia, and the patient is divided into to 2 groups at random, every group of 60 examples; 2 groups of patients no significant difference on sex, age, the course of disease and coincident with severity degree of condition.
Two, trial drug
The medicine that embodiment of the present invention 1-6 is prepared.
Three, Therapeutic Method
120 patients are divided into respectively to 2 groups at random, that is: 1 group of test and test 2, every group of each 60 examples, test 1 group and adopt the prepared capsule treatment of embodiment 1-3, tests 2 groups and adopt the prepared capsule treatment of embodiment 4-6; Oral, one time 3 (0.3g crude drug/grain), 2 times on the one, 7 days is a course for the treatment of, treats altogether 3 courses for the treatment of; Period in a medicine is withdrawn other related drugs and other treatment.
Four, efficacy assessment standard
Cure: pain disappears, and continuous 3 menstrual cycle have no recurrence;
Effectively: pain relief or disappearance, but can not remain 3 more than menstrual cycle;
Invalid: pain has no improvement.
Five, clinical observation result
Clinical observation result is in Table 1.
The clinical observation on the therapeutic effect result of the test of table 1 traditional Chinese medicine composition for treating menalgia of the present invention
The clinical observation on the therapeutic effect result shows, Chinese medicine composition of the present invention has significant curative effect for the menalgia patient; Safety observe to be found, does not observe any clinical adverse, show Chinese medicine composition clinical practice of the present invention safely, have no side effect.
Claims (8)
1. a Chinese medicine composition for the treatment of menalgia, is characterized in that, following each component, consists of: Flos Rosae Chinensis, Vittaria fudzinoi Mak., Caulis Perillae, Cornu Cervi Degelatinatum, Radix seu Caulis Embeliae Parviflorae, Cladonia alpestris (L.) Rabenh., Radix Sanguisorbae Filiformis and Fluoritum.
2. according to Chinese medicine composition claimed in claim 1, it is characterized in that, the weight portion of each component is: Flos Rosae Chinensis 25-40 part, Vittaria fudzinoi Mak. 25-40 part, Caulis Perillae 25-40 part, Cornu Cervi Degelatinatum 10-20 part, Radix seu Caulis Embeliae Parviflorae 10-20 part, Cladonia alpestris (L.) Rabenh. 10-20 part, Radix Sanguisorbae Filiformis 6-13 part, Fluoritum 5-11 part.
3. according to Chinese medicine composition claimed in claim 2, it is characterized in that, the weight portion of each component is: Flos Rosae Chinensis 25-35 part, Vittaria fudzinoi Mak. 25-35 part, Caulis Perillae 25-35 part, Cornu Cervi Degelatinatum 10-15 part, Radix seu Caulis Embeliae Parviflorae 10-15 part, Cladonia alpestris (L.) Rabenh. 10-15 part, Radix Sanguisorbae Filiformis 6-11 part, Fluoritum 5-9 part.
4. according to Chinese medicine composition claimed in claim 3, it is characterized in that, the weight portion of each component is: 30 parts of Flos Rosae Chinensiss, 30 parts of Vittaria fudzinoi Mak.s, 30 parts of Caulis Perillaes, 13 parts of Cornu Cervi Degelatinatums, 13 parts of Radix seu Caulis Embeliae Parviflorae, 13 parts of Cladonia alpestris (L.) Rabenh.s, 9 parts of Radix Sanguisorbae Filiformis, 7 parts of Fluoritum.
5. a Chinese medicine composition for the treatment of menalgia, comprise that each component of following weight portion forms: Flos Rosae Chinensis 25-40 part, Vittaria fudzinoi Mak. 25-40 part, Caulis Perillae 25-40 part, Cornu Cervi Degelatinatum 10-20 part, Radix seu Caulis Embeliae Parviflorae 10-20 part, Cladonia alpestris (L.) Rabenh. 10-20 part, Radix Sanguisorbae Filiformis 6-13 part, Fluoritum 5-11 part, Semen Trigonellae 4-8 part, Radix Linderae 4-8 part, Radix Dipsaci 3-7 part, Herba Epimedii 3-7 part.
6. according to Chinese medicine composition claimed in claim 5, it is characterized in that, the weight portion of each component is: 30 parts of Flos Rosae Chinensiss, 30 parts of Vittaria fudzinoi Mak.s, 30 parts of Caulis Perillaes, 13 parts of Cornu Cervi Degelatinatums, 13 parts of Radix seu Caulis Embeliae Parviflorae, 13 parts of Cladonia alpestris (L.) Rabenh.s, 9 parts of Radix Sanguisorbae Filiformis, 7 parts of Fluoritum, 6 parts of Semen Trigonellae, 6 parts of the Radixs Linderae, 5 parts of Radix Dipsacis, 5 parts of Herba Epimedii.
7. method for preparing any one described Chinese medicine composition of claim 1-6 comprises the following steps:
(1), by described weight proportion, take each crude drug;
(2) each crude drug water is decocted, merge decoction liquor, filter, filtrate is condensed into clear paste, adds adjuvant or the excipient of preparations shaping, and preparations shaping, obtain.
8. any one described Chinese medicine composition of claim 1-6 is treated the purposes in the menalgia medicine in preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310347970.4A CN103393797B (en) | 2013-08-09 | 2013-08-09 | Chinese medicine composition for the treatment of menalgia and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310347970.4A CN103393797B (en) | 2013-08-09 | 2013-08-09 | Chinese medicine composition for the treatment of menalgia and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103393797A true CN103393797A (en) | 2013-11-20 |
| CN103393797B CN103393797B (en) | 2015-11-25 |
Family
ID=49557650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310347970.4A Expired - Fee Related CN103393797B (en) | 2013-08-09 | 2013-08-09 | Chinese medicine composition for the treatment of menalgia and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103393797B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105381322A (en) * | 2015-12-29 | 2016-03-09 | 赵红 | Traditional Chinese medicine for treating dysmenorrhea |
| CN105412888A (en) * | 2015-12-29 | 2016-03-23 | 赵红 | Traditional Chinese medicine preparation used for treating dysmenorrhoea |
| CN105412887A (en) * | 2015-12-29 | 2016-03-23 | 赵红 | Traditional Chinese medicine composition used for treating dysmenorrhea |
| CN112138121A (en) * | 2020-10-13 | 2020-12-29 | 平顶山学院 | A kind of traditional Chinese medicine composition for bathing feet for preventing and treating dysmenorrhea with deficiency of female kidney qi |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005110431A1 (en) * | 2004-05-19 | 2005-11-24 | University Of Manitoba | Herbal product containing glucosamine |
| CN1857450A (en) * | 2006-04-12 | 2006-11-08 | 王信锁 | Chinese medicine prepn for treating dysmenorrhea |
| CN101991738A (en) * | 2009-08-26 | 2011-03-30 | 栗素琴 | Traditional Chinese medicine preparation for treating dysmenorrhea |
| CN102526229A (en) * | 2011-12-27 | 2012-07-04 | 陕西兴邦药业有限公司 | Chinese medicinal composition for regulating menstruation, nourishing blood, regulating flow of qi and dissipating blood stasis and preparation method thereof |
| CN102793774A (en) * | 2012-09-07 | 2012-11-28 | 黄平县润发药业农民专业合作社 | Traditional Chinese medicine for curing infertility |
-
2013
- 2013-08-09 CN CN201310347970.4A patent/CN103393797B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005110431A1 (en) * | 2004-05-19 | 2005-11-24 | University Of Manitoba | Herbal product containing glucosamine |
| CN1857450A (en) * | 2006-04-12 | 2006-11-08 | 王信锁 | Chinese medicine prepn for treating dysmenorrhea |
| CN101991738A (en) * | 2009-08-26 | 2011-03-30 | 栗素琴 | Traditional Chinese medicine preparation for treating dysmenorrhea |
| CN102526229A (en) * | 2011-12-27 | 2012-07-04 | 陕西兴邦药业有限公司 | Chinese medicinal composition for regulating menstruation, nourishing blood, regulating flow of qi and dissipating blood stasis and preparation method thereof |
| CN102793774A (en) * | 2012-09-07 | 2012-11-28 | 黄平县润发药业农民专业合作社 | Traditional Chinese medicine for curing infertility |
Non-Patent Citations (3)
| Title |
|---|
| 胡郁坤等: "《中医单方全书（珍藏本）超值版》", 30 June 2012, 湖南科学技术出版社 * |
| 诸葛梅: "辨证治疗女性不育症64例", 《安徽中医学院学报》 * |
| 陈如英: "《妇女四期饮食宜忌》", 30 September 2001, 江苏科学技术出版社 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105381322A (en) * | 2015-12-29 | 2016-03-09 | 赵红 | Traditional Chinese medicine for treating dysmenorrhea |
| CN105412888A (en) * | 2015-12-29 | 2016-03-23 | 赵红 | Traditional Chinese medicine preparation used for treating dysmenorrhoea |
| CN105412887A (en) * | 2015-12-29 | 2016-03-23 | 赵红 | Traditional Chinese medicine composition used for treating dysmenorrhea |
| CN112138121A (en) * | 2020-10-13 | 2020-12-29 | 平顶山学院 | A kind of traditional Chinese medicine composition for bathing feet for preventing and treating dysmenorrhea with deficiency of female kidney qi |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103393797B (en) | 2015-11-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105124191A (en) | Compound feed for cattle and preparation method of compound feed | |
| CN103393797B (en) | Chinese medicine composition for the treatment of menalgia and preparation method thereof | |
| CN102988939B (en) | Traditional Chinese medicine composition for treating impotence and premature ejaculation and preparation method thereof | |
| CN104338050A (en) | Health care product capable of improving sleep quality | |
| CN101417087B (en) | Medicine for treating gynecology postpartum disease and preparation method thereof | |
| CN103599404A (en) | Traditional Chinese medicinal decoction for treating cervical spondylosis | |
| CN103735934B (en) | A kind of medicine for the treatment of flank pain and preparation method thereof | |
| CN103736003A (en) | Medicament for treating mammary hyperplasia | |
| CN103550383A (en) | Traditional Chinese medicine composition for treating cervical spondylosis | |
| CN106109572A (en) | One treats osteoporotic Chinese medicine composition and preparation method thereof | |
| CN100571747C (en) | A kind of Chinese medicine decoction for the treatment of dysmenorrhea | |
| CN101797291B (en) | Traditional Chinese medicine for treating osteoproliferation | |
| CN101590171B (en) | Chinese medicinal composition for treating acute ankle sprain | |
| CN103212010A (en) | Traditional Chinese medicine composition for treating impotence and preparation method thereof | |
| CN103933324B (en) | Traditional Chinese medicinal pill for treating follicular maldevelopment | |
| CN104056224A (en) | Medicine for treating habitual abortion and preparation method thereof | |
| CN102988937B (en) | Traditional Chinese medicine composition for treating enuresis and preparation method thereof | |
| CN103933388B (en) | Traditional Chinese medicinal preparation for treating cyesedema | |
| CN107582846A (en) | It is a kind of to be used to treat pill medicine of diabetes and preparation method thereof | |
| CN106214831A (en) | One treats leukodermic Chinese medicine for oral administration ball and preparation method thereof | |
| CN104173918A (en) | Traditional Chinese medicinal composition for treating primary dysmenorrhea | |
| CN103055283B (en) | Traditional Chinese medicine preparation for treating post-exercise leg pain | |
| CN101983715B (en) | Medicine for rapidly curing prostatic hyperplasia and preparation method thereof | |
| CN107596264A (en) | A kind of Chinese medicine composition and preparation method for being used to treat cervical spondylopathy | |
| CN106728697A (en) | It is a kind of to treat pill medicine of osteoarthritis and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20151125 Termination date: 20160809 |