CN104922534A - Externally-applied traditional Chinese medicine for treating infantile eczema and preparation method thereof - Google Patents

Abstract

The invention relates to an externally-applied traditional Chinese medicine for treating infantile eczema and a preparation method thereof. The externally-applied traditional Chinese medicine for treating infantile eczema is prepared from the following traditional Chinese medicines in parts by weight: 5-10 parts of lithospermum, 10-20 parts of periostracum cicada, 10-20 parts of semen coicis, 5-10 parts of borneol, 7-10 parts of liquorice, 3-5 parts of syzygium aromaticum, 6-10 parts of semen pharbitidis, 1-5 parts of pericarpium citri reticulatae and 3-8 parts of fructus forsythia. According to the components of the externally-applied traditional Chinese medicine, clove has antisepsis and anti-inflammation effects; semen pharbitidis has the functions of promoting urination and removing toxicity; pericarpium citri reticulatae has the functions of regulating qi and eliminating dampness; fructus forsythia has the functions of clearing heat and removing toxicity; lithospermum has the functions of cooling and activating blood, removing toxicity and promoting eruption; periostracum cicada has the functions of dispelling wind, clearing heat and promoting eruption; semen coicis has the functions of clearing heat and excreting dampness; borneol has the functions of clearing heat and removing toxicity; liquorice has the functions of clearing heat and removing toxicity; after all the traditional Chinese medicines are mixed with one another, and all the components cooperate with one another, with combination of the special preparation method of the externally-applied traditional Chinese medicine, the functions of all the components are completely exerted.

Description

A kind of external used medicine for the treatment of infantile eczema and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of external used medicine for the treatment of infantile eczema and preparation method thereof.

Background technology

Infantile eczema is dermatology common disease and frequently-occurring disease, and infantile eczema is commonly called as infantile eczema, normal sends out in the baby in 1 ~ June, be caused by many factors a kind ofly there is the scytitis obviously oozing out tendency react, fat baby is multiple.Its cause of disease is complicated, form of diverse, and ooze out obviously, position is indefinite, and erythra can recurrent exerbation, if treatment not in time, can occur comparatively significantly rotten to the corn and sepage, be easy to cause secondary infection, often cause uneasiness and the anxiety of infant and the head of a family.

Infant eczema sickness rate has ascendant trend gradually in recent years, does not often touchingly heal, recurrent exerbation.

Western medicine is conventional oral antihistamines at present, external hormones Ointment in Treatment, though can temporary relief of symptoms, drug withdrawal be easily recurred, and is not easily family numbers of patients acceptance.

Summary of the invention

The object of this invention is to provide a kind of external used medicine for the treatment of infantile eczema.

The object of the invention is to be achieved through the following technical solutions, a kind of external used medicine for the treatment of infantile eczema, be made up of the Chinese medicine of following weight portion, Radix Arnebiae (Radix Lithospermi) 5-10 part, Periostracum Cicadae 10-20 part, Semen Coicis 10-20 part, Borneolum Syntheticum 5-10 part, Radix Glycyrrhizae 7-10 part, Flos Caryophylli 3-5 part, Semen Pharbitidis 6-10 part, Pericarpium Citri Reticulatae 1-5 part, Fructus Forsythiae 3-8 part.

Preferably: be made up of the Chinese medicine of following weight portion, Radix Arnebiae (Radix Lithospermi) 5 parts, Periostracum Cicadae 10 parts, Semen Coicis 20 parts, Borneolum Syntheticum 5 parts, 10 parts, Radix Glycyrrhizae, Flos Caryophylli 5 parts, Semen Pharbitidis 6 parts, Pericarpium Citri Reticulatae 5 parts, Fructus Forsythiae 8 parts.

Preferably: be made up of the Chinese medicine of following weight portion, Radix Arnebiae (Radix Lithospermi) 10 parts, Periostracum Cicadae 20 parts, Semen Coicis 10 parts, Borneolum Syntheticum 10 parts, 7 parts, Radix Glycyrrhizae, Flos Caryophylli 3 parts, Semen Pharbitidis 10 parts, Pericarpium Citri Reticulatae 1 part, Fructus Forsythiae 3 parts.

The present invention also provides a kind of method preparing above-mentioned external used medicine, the steps include:

1) Flos Caryophylli, Semen Pharbitidis, Pericarpium Citri Reticulatae, Fructus Forsythiae powder are broken to 80-100 order, then put into the ethanol of appropriate 95%, the amount of ethanol did not have all Chinese medicine, continued 8-24h and extracted, collecting by filtration filtrate at 40-50 DEG C; Solid residue is put into again the ethanol of 95%, the amount of ethanol did not have all Chinese medicine, continued 8-24h and extracted, collecting by filtration filtrate at 40-50 DEG C; Twice filtrate carries out being evaporated to thickness paste at 50-60 DEG C;

2) Radix Arnebiae (Radix Lithospermi), Radix Glycyrrhizae are put into vegetable oil, lixiviate 6-24h at 40-60 DEG C, filter and obtain lixiviating solution;

3) by Periostracum Cicadae, Semen Coicis, Borneolum Syntheticum powder is broken to 80-100 order, with step 1) paste and step 2) in lixiviating solution fully mix.

In medicine of the present invention, Flos Caryophylli, Semen Pharbitidis, Pericarpium Citri Reticulatae, the effective ingredient of Fructus Forsythiae adopts alcohol extracting method fully to extract, Radix Arnebiae (Radix Lithospermi), Radix Glycyrrhizae employing immersion method can by extracts active ingredients, then by the Periostracum Cicadae after pulverizing, Semen Coicis, Borneolum Syntheticum adds in prescription, the high efficiency extraction of various drug component effective ingredient can be realized, in each component, Flos Caryophylli has antibacterial and anti-inflammation functions, Semen Pharbitidis promoting diuresis to remove toxic substance, Pericarpium Citri Reticulatae is regulated the flow of vital energy dampness, Fructus Forsythiae heat-clearing and toxic substances removing, Radix Arnebiae (Radix Lithospermi) removing heat from blood and promoting blood circulation, removing toxic substances rash, Periostracum Cicadae falls apart wind heat extraction rash, Semen Coicis heat clearing away eliminating dampness by diuresis, Borneolum Syntheticum heat-clearing and toxic substances removing, Radix Glycyrrhizae heat-clearing and toxic substances removing coordinating the actions of various ingredients in a prescription, cooperatively interact between each component, in conjunction with the special preparation method in the present invention, effect of each component is played comprehensively.

Detailed description of the invention

Embodiment 1

Component: Radix Arnebiae (Radix Lithospermi) 5 parts, Periostracum Cicadae 10 parts, Semen Coicis 20 parts, Borneolum Syntheticum 5 parts, 10 parts, Radix Glycyrrhizae, Flos Caryophylli 5 parts, Semen Pharbitidis 6 parts, Pericarpium Citri Reticulatae 5 parts, Fructus Forsythiae 8 parts.

Method:

1) Flos Caryophylli, Semen Pharbitidis, Pericarpium Citri Reticulatae, Fructus Forsythiae powder are broken to 80-100 order, then put into the ethanol of appropriate 95%, the amount of ethanol did not have all Chinese medicine, continued 8h and extracted, collecting by filtration filtrate at 40 DEG C; Solid residue is put into again the ethanol of 95%, the amount of ethanol did not have all Chinese medicine, continued 8h and extracted, collecting by filtration filtrate at 50 DEG C; Twice filtrate carries out being evaporated to thickness paste at 60 DEG C;

2) Radix Arnebiae (Radix Lithospermi), Radix Glycyrrhizae are put into vegetable oil, lixiviate 6h at 40 DEG C, filter and obtain lixiviating solution;

3) by Periostracum Cicadae, Semen Coicis, Borneolum Syntheticum powder is broken to 80-100 order, with step 1) paste and step 2) in lixiviating solution fully mix.

Embodiment 2

Component: be made up of the Chinese medicine of following weight portion, Radix Arnebiae (Radix Lithospermi) 10 parts, Periostracum Cicadae 20 parts, Semen Coicis 10 parts, Borneolum Syntheticum 10 parts, 7 parts, Radix Glycyrrhizae, Flos Caryophylli 3 parts, Semen Pharbitidis 10 parts, Pericarpium Citri Reticulatae 1 part, Fructus Forsythiae 3 parts.

Method:

1) Flos Caryophylli, Semen Pharbitidis, Pericarpium Citri Reticulatae, Fructus Forsythiae powder are broken to 80-100 order, then put into the ethanol of appropriate 95%, the amount of ethanol did not have all Chinese medicine, continued 24h and extracted, collecting by filtration filtrate at 50 DEG C; Solid residue is put into again the ethanol of 95%, the amount of ethanol did not have all Chinese medicine, continued 24h and extracted, collecting by filtration filtrate at 50 DEG C; Twice filtrate carries out being evaporated to thickness paste at 50 DEG C;

2) Radix Arnebiae (Radix Lithospermi), Radix Glycyrrhizae are put into vegetable oil, lixiviate 24h at 60 DEG C, filter and obtain lixiviating solution;

3) by Periostracum Cicadae, Semen Coicis, Borneolum Syntheticum powder is broken to 80-100 order, with step 1) paste and step 2) in lixiviating solution fully mix.

Clinical data

60 routine patients, man 28 example, female 32 example; Minimum 20 days of age, maximum 2 years old; The course of disease is the shortest 3 days, the longest 6 months; Send out in face 10 example, send out in scalp 6 example, send out in forehead 5 example, send out in flexor of elbow joints side 4 example, send out and bend side 15 example in knee joint, send out in buttocks 6 example, multiple 14 examples in the whole body.

Diagnostic criteria is with reference to " Chinese medical disease Standardization of diagnosis and curative effect ".

1. skin lesion is pleomorphism, as flushing, pimple, water scar, erosion, ooze out, silly skin, desquamation, constant kind form exists simultaneously.

2. onset is anxious, and scorching hot, violent rash is itched.

3. skin lesion is often symmetrical, common with places such as head, face, distal limbs, scrotum.Can general whole body.

4. can develop into subacute or chronic eczema, time light time heavy, repeatedly do not heal.

Patient is divided into 2 groups at random, uses the liniment of preparation in embodiment 1 and embodiment 2 to treat respectively.During treatment, with medical cotton stick wiping affected part, each 5 minutes, every day 2 times.Continuous treatment one week.

Criterion of therapeutical effect

With reference to " Chinese medical disease Standardization of diagnosis and curative effect " that State Administration of Traditional Chinese Medicine promulgates.

Cure: skin lesion disappears.

Take a turn for the better: skin lesion disappears more than 30%.

Do not heal: skin lesion disappears less than 30%.

Through treatment one week, find that the skin lesion of whole infant disappears, all meet the criterion of therapeutical effect of healing, wherein adopt the patient treatment 5 days of the medicine of embodiment 2 afterwards all infant all cure.

Claims (4)

1. treat an external used medicine for infantile eczema, it is characterized in that: be made up of the Chinese medicine of following weight portion, Radix Arnebiae (Radix Lithospermi) 5-10 part, Periostracum Cicadae 10-20 part, Semen Coicis 10-20 part, Borneolum Syntheticum 5-10 part, Radix Glycyrrhizae 7-10 part, Flos Caryophylli 3-5 part, Semen Pharbitidis 6-10 part, Pericarpium Citri Reticulatae 1-5 part, Fructus Forsythiae 3-8 part.

2. a kind of external used medicine for the treatment of infantile eczema as claimed in claim 1, is characterized in that: be made up of the Chinese medicine of following weight portion, Radix Arnebiae (Radix Lithospermi) 5 parts, Periostracum Cicadae 10 parts, Semen Coicis 20 parts, Borneolum Syntheticum 5 parts, 10 parts, Radix Glycyrrhizae, Flos Caryophylli 5 parts, Semen Pharbitidis 6 parts, Pericarpium Citri Reticulatae 5 parts, Fructus Forsythiae 8 parts.

3. a kind of external used medicine for the treatment of infantile eczema as claimed in claim 1, is characterized in that: be made up of the Chinese medicine of following weight portion, Radix Arnebiae (Radix Lithospermi) 10 parts, Periostracum Cicadae 20 parts, Semen Coicis 10 parts, Borneolum Syntheticum 10 parts, 7 parts, Radix Glycyrrhizae, Flos Caryophylli 3 parts, Semen Pharbitidis 10 parts, Pericarpium Citri Reticulatae 1 part, Fructus Forsythiae 3 parts.

4. prepare the method for external used medicine described in claim 1-3, it is characterized in that:

1) Flos Caryophylli, Semen Pharbitidis, Pericarpium Citri Reticulatae, Fructus Forsythiae powder are broken to 80-100 order, then put into the ethanol of appropriate 95%, the amount of ethanol did not have all Chinese medicine, continued 8-24h and extracted, collecting by filtration filtrate at 40-50 DEG C; Solid residue is put into again the ethanol of 95%, the amount of ethanol did not have all Chinese medicine, continued 8-24h and extracted, collecting by filtration filtrate at 40-50 DEG C; Twice filtrate carries out being evaporated to thickness paste at 50-60 DEG C;

2) Radix Arnebiae (Radix Lithospermi), Radix Glycyrrhizae are put into vegetable oil, lixiviate 6-24h at 40-60 DEG C, filter and obtain lixiviating solution;

3) by Periostracum Cicadae, Semen Coicis, Borneolum Syntheticum powder is broken to 80-100 order, with step 1) paste and step 2) in lixiviating solution fully mix.