CN104922507A - Traditional Chinese medicine for treating coronary heart disease stable angina pectoris complicated with diabetes - Google Patents

Abstract

The invention belongs to the technical field of medicines and particularly relates to a traditional Chinese medicine for treating coronary heart disease stable angina pectoris complicated with diabetes. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 16-24 parts of gypsum, 5-13 parts of rhizoma anemarrhenae, 8-16 parts of dried rehmannia root, 5-13 parts of radix ophiopogonis, 11-19 parts of polished round-grained rice, 5-13 parts of radix puerariae, 4-8 parts of agastache rugosus, 6-14 parts of ginseng, 11-19 parts of codonopsis pilosula, 11-19 parts of radix pseudostellariae, 8-16 parts of bighead atractylodes rhizome, 5-13 parts of rhizoma atractylodis, 5-13 parts of pinellia ternate, 5-13 parts of rhizoma arisaematis, 16-24 parts of succus bambusae, 6-14 parts of trichosanthes kirilowii maxim, 5-13 parts of thunberg fritillary bulb, 5-13 parts of ligusticum wallichii, 5-13 parts of rhizoma corydalis, 5-13 parts of radix salviae miltiorrhizae, 5-13 parts of safflower carthamus, 1-5 parts of leech and 4-8 parts of liquorice. The traditional Chinese medicine has the functions of improving exercise tolerance of patients with coronary heart disease, reducing paroxysm frequency of angina, reducing blood sugar, improving living quality of the patients and relieving traditional Chinese medicine syndromes of the patients with coronary heart disease stable angina pectoris complicated with diabetes.

Description

A kind of Chinese medicine for the treatment of Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes

Technical field

The invention belongs to medical art, be specifically related to a kind of Chinese medicine for the treatment of Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes.

Background technology

Coronary heart disease (Coronary heart disease CHD) refers to because coronary atherosclerosis causes the narrow of vessel lumen even to block, cause cardiac muscle that ischemia, anoxia and a kind of heart disease of causing occur, be clinical in the most common cardiovascular disease, and the life and health of the mankind in its serious harm.Along with improving constantly of our people's living standard, the sickness rate of coronary heart disease is in the trend risen year by year.Stable angina pectoris (Stable angina pectoris SAP) is the main Types of coronary heart disease, and its delay repeatedly, affects quality of life of patient and life-threatening safety.Treating Stable Angina Pectoris of Coronary Artery Disease belongs to the category of " thoracic obstruction ", " pained " in motherland's traditional medicine.The many complication with diabetes of Treating Stable Angina Pectoris of Coronary Artery Disease clinically, at present, the curative effect of medication for the treatment of these diseases is single, and what cause needs of patients to be taken is of a great variety, and the time differs, and patient consumes bothers.Meanwhile, the interaction between medicine is clear and definite not, causes overall curative effect good not.

Summary of the invention

Technical problem to be solved by this invention avoids the weak point existing for above-mentioned prior art, a kind of Chinese medicine for the treatment of Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes is provided, this Chinese medicine have improve exercise in coronary disease patients tolerance, reduce angina pectoris attacks number of times, reduce blood glucose, improve the life quality of patient, the advantage of the tcm syndrome of the Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes patient of improvement.

The present invention is achieved through the following technical solutions:

Treat a Chinese medicine for Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes, be made up of the raw material of Chinese medicine medicine of following weight portion:

Gypsum Fibrosum 16-24 part, Rhizoma Anemarrhenae 5-13 part, Radix Rehmanniae 8-16 part, Radix Ophiopogonis 5-13 part, Semen oryzae sativae 11-19 part, Radix Puerariae 5-13 part, Herba Pogostemonis 4-8 part, Radix Ginseng 6-14 part, Radix Codonopsis 11-19 part, Radix Pseudostellariae 11-19 part, Rhizoma Atractylodis Macrocephalae 8-16 part, Rhizoma Atractylodis 5-13 part, Rhizoma Pinelliae 5-13 part, Rhizoma Arisaematis 5-13 part, Succus Bambusae 16-24 part, Fructus Trichosanthis 6-14 part, Bulbus Fritillariae Thunbergii 5-13 part, Rhizoma Chuanxiong 5-13 part, Rhizoma Corydalis 5-13 part, Radix Salviae Miltiorrhizae 5-13 part, Flos Carthami 5-13 part, Hirudo 1-5 part, Radix Glycyrrhizae 4-8 part.

Preferably, the Chinese medicine of above-mentioned treatment Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes, be made up of the raw material of Chinese medicine medicine of following weight portion:

Gypsum Fibrosum 18-22 part, Rhizoma Anemarrhenae 7-11 part, Radix Rehmanniae 10-14 part, Radix Ophiopogonis 7-11 part, Semen oryzae sativae 13-17 part, Radix Puerariae 7-11 part, Herba Pogostemonis 5-7 part, Radix Ginseng 8-12 part, Radix Codonopsis 13-17 part, Radix Pseudostellariae 13-17 part, Rhizoma Atractylodis Macrocephalae 10-14 part, Rhizoma Atractylodis 7-11 part, Rhizoma Pinelliae 7-11 part, Rhizoma Arisaematis 7-11 part, Succus Bambusae 18-22 part, Fructus Trichosanthis 8-12 part, Bulbus Fritillariae Thunbergii 7-11 part, Rhizoma Chuanxiong 7-11 part, Rhizoma Corydalis 7-11 part, Radix Salviae Miltiorrhizae 7-11 part, Flos Carthami 7-11 part, Hirudo 2-4 part, Radix Glycyrrhizae 5-7 part.

Preferred, the Chinese medicine of above-mentioned treatment Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes, be made up of the raw material of Chinese medicine medicine of following weight portion:

20 parts, Gypsum Fibrosum, the Rhizoma Anemarrhenae 9 parts, Radix Rehmanniae 12 parts, Radix Ophiopogonis 9 parts, Semen oryzae sativae 15 parts, Radix Puerariae 9 parts, Herba Pogostemonis 6 parts, Radix Ginseng 10 parts, Radix Codonopsis 15 parts, Radix Pseudostellariae 15 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, Rhizoma Atractylodis 9 parts, the Rhizoma Pinelliae 9 parts, Rhizoma Arisaematis 9 parts, Succus Bambusae 20 parts, Fructus Trichosanthis 10 parts, Bulbus Fritillariae Thunbergii 9 parts, Rhizoma Chuanxiong 9 parts, Rhizoma Corydalis 9 parts, Radix Salviae Miltiorrhizae 9 parts, 9 parts, Flos Carthami, Hirudo 3 parts, 6 parts, Radix Glycyrrhizae.

The ratio of above weight proportion is through that science screening obtains, and for especial patient, as serious symptom or mild, fat or modest patient, can the proportioning of amount of corresponding adjustment composition, and increase or reduce being no more than 100%, drug effect is substantially constant.

The weight portion of said medicine, if in units of g, the normally consumption of 1 dose.

The indication of Chinese medicine of the present invention: for Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes patient.

The taboo item of Chinese medicine of the present invention: the fasting for the treatment of period in a medicine is greasy, raw and cold, the smelling of fish or mutton, irritant and stodgy food.

In the Chinese medicine for the treatment of Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes of the present invention:

Gypsum Fibrosum: nature and flavor: sweet, pungent, Great Cold.Attach to the lung and stomach meridians.Function cures mainly: clearing away heat-fire, and relieving restlessness is quenched the thirst.For fever caused by exogenous pathogenic factors, high hot excessive thirst, dyspnea and cough due to lung-heat, the high Sheng of stomach-fire, headache, toothache." not Lu ": " except seasonal epidemic pathogens headache fever of the body, three burnt large heat, skin heat, heat of the diaphragm in the intestines and stomach, expelling pathogenic factors from muscles by diaphoresis, restlessness accompanied by ascending of QI of only quenching one's thirst, abdominal distention is panted breath cruelly, pharynx heat.Also can do to bathe soup.”

" property of medicine opinion ": " control cold headache as split, high fever, skin is as dry in fire, excessive thirst, and expelling pathogenic factors from muscles goes out malicious antiperspirant, ties in main logical stomach, unhappy, and spasm in the epigastrium is irritated, controls lip dry burnt.Simmer tea with Herba Alii fistulosi and decaptitate bitterly. " " pearl sac ": " only YANG MING headache, only quenches one's thirst, heatstroke, hectic fever." " medication heart method ": " through medicine in Great Cold, lung moistening heat extraction, disperses YIN pathogen to stomach, slow spleen QI invigorating." " Amplification on Materia Medica addendum ": " grind as end, it is as large in Semen phaseoli radiati that vinegar grinds ball, to rush down stomach-fire, phlegm-fire, food stagnation.”

The Rhizoma Anemarrhenae: nature and flavor: bitter, sweet, cold.Return lung, stomach, kidney channel.Function cures mainly: clearing away heat-fire, promotes the production of body fluid and moisturizes.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation." herbal classic ": " main quenching one's thirst is hankered, except pathogen limbs edema, and lower water, tonifying for the deficiency, QI invigorating." " property of medicine opinion ": " cure mainly vexed hot-tempered vexed, the contact of bone hot labor, raw general debility during puerperium, kidney qi labor, the loathing of cold is deficient, suffers from the empty and xerostomia of people, adds and use it." " Japan hanako materia medica ": " profit cardiopulmonary, tonify deficiency is weary, and spasmolytic of feeling at ease is throbbed with fear for logical small intestinal, expectorant antitussive." Zhang Yuansu: " the cool heart reduces phlegm and internal heat, and controls positive naked light heat, rushes down bladder kidney channel fire, pyretic headache, dysentery lumbago, stench in larynx." Wang Haogu: " and purte the white, kidney nourishing water, control the gate of vitality mutually fire have a surplus.”

Radix Rehmanniae: nature and flavor: Radix Rehmanniae: sweet, cold.GUIXIN, liver, kidney channel.Function cures mainly: clearing away heat and cooling blood, and yin nourishing is promoted the production of body fluid.For calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis sends out speckle dermexanthesis." not Lu ": " housewife people's metrorrhagia blood is more than, and the thin heart on puerperal blood, absolutely vexed, be harmful to the health, vaginal bleeding due to excessive movement of fetus, tire do not fall, falling down wrist is rolled over, blood stasis stagnant blood, and epistaxis is spitted blood, and all smashes drink." " property of medicine opinion ": " and Xie Zhure, removing blood stasis, the tonneau moon water blockage exhausted, also dredging water passages, smashes thin trusted subordinate, can repercussive blood.Empty and the frequent fever of patient, adds and uses it." " medicine class on the analogy of natural things ": " removing heat from blood, enriches blood, the kidney invigorating water kidney-YIN being deficient." " Bencao Congxin ": " disappear small intestine fire, clearing away dryness gold, and flat all blood is inverse, and repercussive stimulates the menstrual flow.Control and tell nosebleed metrorrhagia, pyretic toxicity dysentery, the intestines and stomach is as burnt, and typhoid fever pestilence pox is demonstrate,proved, Zhu great Re, drinking a large amount of water due to extreme thirst, and folding falls exhausted muscle, sharp defecation.”

Radix Ophiopogonis: nature and flavor: sweet, micro-hardship, is slightly cold.GUIXIN, lung, stomach warp.Function cures mainly: YIN nourishing and the production of body fluid promoting, and lung moistening clears away heart-fire.For dryness of the lung dry cough.Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria." herbal classic ": " main stagnation of QI in chest and abdomen, damaging the spleen and stomach wound is full, and stomach channels is exhausted, and weakness and emaciation is losed heart." " not Lu ": " treat heavy sensation of the body icteric sclera, rami cardiaci inferiores is full, asthenia exopathogenic heat, and dry mouth is thirsty, anti-nausea, and more flaccidity falls, and reinforcing YIN-essence benefit essence, during rapid digestion of food is adjusted, protects god, determine lung qi, settling five organs, makes us fertile and is good for." " property of medicine opinion ": " control pyretic toxicity, only excessive thirst, main flood appearance podomere edema, lower water.Control consumptive lung disease vomiting pus, master lets out essence." supplement to the Herbal: " control cold and heat body labor, lower phlegm retention." " medication heart method ": " reinforcing the heart QI-insufficiency and control the absurd row of blood.”

Semen oryzae sativae: nature and flavor: sweet is flat.Return spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, invigorating the spleen and regulating the stomach, relieving thirst and restlessness, antidiarrheal dysentery." not Lu ": " main QI invigorating, only tired, stopping leak." " a thousand pieces of gold dietetic therapy ": " flat gastric qi, longue meat." Meng numerous: " warming middle-JIAO, QI invigorating mend lower unit." " Japan hanako materia medica ": " strengthening bone and muscle mends the intestines and stomach." " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " control weakness, reinforcing YIN-essence bone strengthening, promotes the production of body fluid, improving eyesight, long intelligence." " detailed outline ": " Semen oryzae sativae medicated porridge: diuresis, only excessive thirst, support the intestines and stomach." " parched rice soup: stomach reinforcing dehumidifies.”

Radix Puerariae: nature and flavor: sweet, pungent, cool.Return spleen, stomach warp.Function cures mainly: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hyperglycemia neck pain.

" herbal classic ": " master quenches one's thirst, and body is too warm, vomiting, and all numbness plays cloudy gas, separates all poison." " not Lu ": " excessive cold invading middle-JIAO(the spleen and stomach) wind headache of curing the wound, expelling pathogenic factors from muscles, delivers, and perspires, loosing the interspaces of skin and muscles.Treat incised wound, pain relieving, side of body wind pain." " juice of taking root, treatment is quenched one's thirst, typhoid fever high fever." TAO Hong-Jing: " survivor smashes extracting juice and drinks it, separates epidemic febrile disease heating.Radix Puerariae is bits, treats incised wound and to break blood, also treat malaria and skin ulcer." " property of medicine opinion ": " and control sky capable on gas, vomiting, whetting the appetite, principal solution alcoholism, only excessive thirst.Endure bits and control incised wound, when controlling, disease is antipyretic." Tang Materia Medica: " Japan hanako materia medica ": " control chest and diaphragm heat, vexed sultry mad, hemostasis dysentery, logical small intestinal, evacuation of pus removing blood stasis, deposited snakeworm nibbles." " medical science opens former ": " thirsty except taste deficiency-heat.”

Herba Pogostemonis: nature and flavor: pungent, tepor.Be included into lung, spleen, stomach warp.Function cures mainly: fast gas, and in, ward off dirty, damp eliminating.Cure cold heat-damp in summer, cold and heat, and headache, breast gastral cavity painful abdominal mass is vexed, and vomiting is had loose bowels, malaria, dysentery, halitosis." not Lu ": " treat edema due to wind pathogen poison swollen, remove bad odor, treat cholera, pained." " pearl sac ": " benefit defends gas, and stomach reinforcing gas, enters diet, controls again and tells inverse cholera." Materia Medica of Decoction: " the fast gas of warming middle-JIAO.The deficiency of the lung has cold, and the part of the body cavity above the diaphragm housing the heart and lungs stops up heat, and halitosis of drinking, decocts soup and gargle." " book on Chinese herbal medicine is stated ": " wet, the heat-damp in summer of cold expelling, hot and suffocating, damp and hot.Control diseases caused by exogenous pathogenic factor cold-evil, internal injury diet, or cold humidity hysteresis hindered by diet, epidemic pathogenic factors from mountains, not FUSHUI soil, cold and heat do the diseases such as malaria." " book on Chinese herbal medicine is new again ": " inducing diaphoresis to expel pathogens, dampness removing, except wind, relieves heat and thirst.Stopping vomiting tells cholera, malaria, dysentery, skin ulcer scabies.Stalk: can sore throat be controlled, reduce phlegm, cough-relieving coughs.”

Radix Ginseng: nature and flavor: sweet, micro-hardship is flat; Return spleen, lung, heart channel; Function cures mainly: strongly invigorating primordial QI, and multiple arteries and veins takes off admittedly, and invigorating the spleen to benefit the lung, promotes the production of body fluid, and calms the nerves.For weak body and prostration, cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung is breathed with cough, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, prolonged illness weakness with emaciation, palpitation with fear insomnia, sexual impotence cold womb; Heart failure, cardiogenic shock." property of medicine opinion ": " deficient thin and weak, tell inverse lower food, only cholera unhappiness is vomitted the sound of vomiting, and tonifying five ZANG-organs six internal organs, keep god in guarantor for main the five internal organs QI-insufficiency, five kinds of strain and seven kinds of impairment." " disappear expectorant in the heart, main consumptive lung disease vomiting pus and epilepsy disease, and cold air is against upper, and the lower food of typhoid fever, suffers from people's void and dreaminess is diverse and confused, add and use it." " medicine origin ": " control taste YANG QI deficiency and lung qi to urge, lose heart, weak breath, during invigorating middle warmer is slow, pathogenic fire in eliminating the pathogens from the lung taste.”

Radix Codonopsis: nature and flavor: sweet is flat.Return spleen, lung meridian.Function cures mainly: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst." Bencao Congxin ": " invigorating the spleen and replenishing QI, and taste, relieving thirst and restlessness." " medicinal herbs among the people of science ": " hematinic.Be applicable to chronic anaemia, chlorosis, leukemia, adenopathy, rickets." " Chinese crude drug handbook ": " control asthenia internal injury, intestinal cold in the stomach, slide and rush down chronic dysentery, asthma excessive thirst, heating spontaneous perspiration, metrorrhagia, tire produce all diseases.”

Radix Pseudostellariae: nature and flavor: sweet, micro-hardship is flat.Gui Jing: return spleen, lung meridian.Function cures mainly: replenishing QI to invigorate the spleen, promoting the production of body fluid for nourishing the lung.Tired for insufficiency of the spleen body, inappetence, weak after being ill, deficiency of both vital energy and Yin, spontaneous perspiration is thirsty, dryness of the lung dry cough." Bencao Congxin ": " strongly invigorating primordial QI." " book on Chinese herbal medicine is new again ": " control the deficiency of vital energy dryness of the lung, spleen reinforcing soil, consumer edema, reduces phlegm and quenches the thirst." " decoction pieces is newly joined ": " spleen reinforcing lung vigour, hidroschesis promotes the production of body fluid, and determines void and throbs with fear." " Shaanxi Chinese herbal medicine ": " invigorating qi and benefiting blood, spleen invigorating is promoted the production of body fluid.After curing the disease, body is empty, cough due to deficiency of the lung, insufficiency of the spleen diarrhoea, children's's sweating due to debility, cardiopalmus, xerostomia, anorexia.”

The Rhizoma Atractylodis Macrocephalae: nature and flavor: bitter, sweet, temperature.Gui Jing: return spleen, stomach warp.Function cures mainly: invigorating the spleen and benefiting QI, dampness diuretic, and hidroschesis is antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement." medicine origin ": " dehumidifying benefit is dry, and middle QI invigorating, warming middle-JIAO, go in taste wet, except gastric heat, strong taste, enter diet, stomach function regulating, born fluid, and main flesh heat, extremity are sleepy, and order is not for opening, and tiredness with somnolence, anorexia, quenches the thirst, antiabortive." Li Gao: " go Zhu Jingzhong wet and manage taste." Wang Haogu: " strengthening the spleen in reason, tonifying liver wind is empty, main stiffness of the tongue, vomiting right after eating, gastric abscess, heavy sensation of the whole body, acute pain in the epigastrium, water painful abdominal mass under the heart, and chong channel is disease, inverse gas pain in the abdomen, periumbilical pain." " Amplification on Materia Medica addendum ": " and there is antiperspirant then to stop, lossless, send out.Can be disappeared deficiency-phlegm.”

Rhizoma Atractylodis: nature and flavor: pungent, bitter, temperature.Return spleen, stomach, Liver Channel.Function cures mainly: drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia." pearl sac ": " stomach invigorating can pacify spleen, non-this of all damp-edema can not remove." Li Gao: " dehumidifying diaphoresis, stomach invigorating peace spleen, controls flaccidity key medicine." Zhu Zhenheng: " loose wind QI invigorating, total solution is all strongly fragrant." " detailed outline ": " control damp-phlegm prolonged fluid-retention, or hold blood stasis under the arm and become nest capsule, and spleen wets dirty, turbid drop leukorrhagia, slidingly rush down hemorrhoidal hamorrhage." " beautiful Chinese catalpa medicine solution ": " dry native diuretic, lets out drink expectorant, clots absorbing, dissipating depression of QI, goes Lou, changes tinea ， Chu Disorder, and reason acid regurgitation removing the necrotic tissue, ward off mountains and rivers communicable subtropical diseases, the flaccidity returning muscles and bones is soft, excessive muddiness of urinating clearly.”

The Rhizoma Pinelliae: nature and flavor: pungent, temperature; Poisonous.Return spleen, stomach, lung meridian.Function cures mainly: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache, vomiting regurgitation, and breast gastral cavity painful abdominal mass is vexed, globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is used for stopping nausea and vomiting by lowering the adverse flow of QI." herbal classic ": " therapeutic method to keep the adverse QI flowing downwards, laryngopharynx swells and ache, and dizziness breast is swollen, cough with dyspnea, borborygmus, hidroschesis for main typhoid fever cold and heat, hardness in the epigastrium." " not Lu ": " the full knot of diabetes with polydipsia as the prominent symptom abdomen chest and diaphragm expectorant heat, cough with dyspnea, the hard painful abdominal mass of acute pain in the epigastrium, seasonal epidemic pathogens vomiting; Subduing inflammation, induced abortion, treats dull yellowish colored skin, happy damp appearance.Raw make us telling, ripely to make us down." " property of medicine opinion ": " anti-nausea, go expectorant in the heart full, lower lung qi, master coughs knot for expectorant saliva, appetite promoting and the spleen strengthening.New survivor rub be coated with carbuncle do not disappear, can tumor wart be removed.The deficiency of vital energy and have mental disorder, adds and uses it." " dry stomach wets " curing mainly secret wanting " cloud, reduces phlegm, strengthening the spleen gastric qi, dispersing swelling and dissipating binds, removes sputum in the heart.”

Rhizoma Arisaematis: nature and flavor: bitter, pungent, temperature; Poisonous.Return lung, liver, spleen channel.Function cures mainly: drying dampness to eliminate phlegm, expellings wind and relieving convulsion, mass dissipating and swelling eliminating.For pertinacious phlegm cough, dizziness due to wind-phlegm, middle wind-phlegm is stopped up, facial hemiparalysis, hemiplegia, epilepsy, infantile convulsion, tetanus.Life uses external treatment carbuncle, snake bite and insect sting." herbal classic ": " main pained, cold and heat, stagnation of QI, gathers, fullness in the epigastrium especially referring to the abcess of the abdomen in ancient times, muscle and tendon injury, flaccidity, arrests slow, dredging water passages." " Kaibao Bencao ": " and main apoplexy, expectorant, paralysis, the therapeutic method to keep the adverse QI flowing downwards, broken hard long-pending, subduing inflammation, sharp chest and diaphragm, loose blood induced abortion.”

Succus Bambusae: nature and flavor: sweetness and bitterness, cold.GUIXIN, stomach warp.Function cures mainly: the sliding expectorant of heat clearing away, relieving convulsion sharp key.Control middle wind-phlegm fan, lung-heat expectorant is stopped up, infantile convulsion, epilepsy, high fever excessive thirst, restlessness during pregnancy, tetanus." not Lu ": " treat sudden and violent apoplexy migratory arthralgia, in the heart large heat, only unhappy (have under " detailed outline " last sentence ' recurrence caused by overexertion of quenching one's thirst ')." " property of medicine opinion ": " control apoplexy aphonia in silence." supplement to the Herbal: " yearningly vexed for a long time." " detailed outline ": " control eclampsia gravidarum puerperal tetanus, separate Extract Aconiti Radicis sucus poison." essentials of Matea Medica: " pathogenic wind expelling pathogenic fire reducing, moisturizes row expectorant, and nourish blood tonifying YIN, sharp key tomorrow.Control apoplexy locked mouth, the large heat of expectorant fan, puerperal tetanus is demented, and unhappiness is quenched one's thirst, spontaneous sweating due to deficientcy of blood." " book on Chinese herbal medicine is new again ": " liver-fire, falls in clearing away heart-fire, reduces phlegm and quenches the thirst, and antipyretic relieving restlessness, controls toothache, bright eyes.”

Fructus Trichosanthis: nature and flavor: sweet, micro-hardship, cold.Return lung, stomach, large intestine channel.Effect: clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturizes laxation.For cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, blocked-up chest feeling of fullness, acute mastitis, lung abscess, and acute appendicitis swells and ache, constipation." not Lu ": " the main thoracic obstruction." become endlessly: " logical hot and suffocating in the heart." " product remittance essence is wanted ": " disappear knot expectorant, loose carbuncle poison.”

Bulbus Fritillariae Thunbergii: nature and flavor: bitter, cold.Return lung, heart channel.Function cures mainly: heat clearing away eliminating stagnation, preventing phlegm from forming and stopping coughing, for wind-heat invading the lung, and phlegm-fire cough, lung abscess, acute mastitis, scrofula, sore." book on Chinese herbal medicine is just ": " control greatly lung abscess lung to wither, cough with asthma, spit blood, mental disorder, falls most in epistaxis, kind relieving stagnation, and relieve the pain pain, and relieving distension is full, clearing away liver-fire, improve visual and auditory acuity, except seasonal epidemic pathogens dysphoria with smothery sensation, and jaundice stranguria with urinary obstruction, hematuria of having blood in stool; Relieving heat toxin, kill parasites and treat sore throat, scrofula, acute mastitis carbuncle on the back, all carbuncle and ulcer toxic swellings, damp and hot malignant boil, anal fistula, incised wound is hemorrhage, burn pain, and than Bulbus Fritillariae Cirrhosae, the merit of falling clearly, not less than several times." " Bencao Congxin ": " when going, feel wind-phlegm." " detailed outline is picked up any lost article from the road ": " detoxify sharp expectorant, opens lung qi dispersing gas, and all lung men folder wind-fire has expectorant, and person should this." " Shandong Chinese herbal medicine handbook ": " removing heat from the lung and dissipating phlegm, antacid, removing toxic substances.Cure cold cough, and stomachache acid regurgitation, carbuncle poison swells and ache.”

Rhizoma Chuanxiong: nature and flavor: pungent, temperature.Return liver, gallbladder, pericardium channel.Function cures mainly: blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia." herbal classic ": " main apoplexy enters brain headache, arthralgia due to cold, clonic spasm of the muscle emergency, and gold wound, married woman's blood closes loss of fecundity." " not Lu ": " and except cold dynamic in brain, on face, urticaria goes, order lacrimation, profuse nasal discharge and spittle, before we notice it as liquor-saturated, all cold gas, the hard pain of trusted subordinate, attacked by pestiferous factors, soldier is anxious to swell and ache, side of body wind pain, warming middle-JIAO endogenous cold." TAO Hong-Jing: " tooth root bleeder, is recovered more than containing." " property of medicine opinion ": " control waist foot weak, hemiplegia, main afterbirth does not go out, and controls cold type of pain in abdomen." " Japan hanako materia medica ": " control a wind cutting, all gas, all strains, all blood, mend five kinds of over strain, strengthening bone and muscle, adjusts many arteries and veins, and broken Disorder ties stagnated blood, supports fresh blood, puts on flesh, serious epistaxis, spits blood and hematuria, hemorrhoid complicated by anal fistula, brain carbuncle carbuncle on the back, and scrofula wart is gone to live in the household of one's in-laws on getting married, skin ulcer scabies, and evacuation of pus repercussive blood." " medicine origin ": " enrich blood, control headache due to deficiency of blood." 7. Wang Haogu: " searches irritability, tonifying liver blood, and profit liver is dry, mends wind empty." " detailed outline ": " dampness, antidiarrheal dysentery, activating QI to alleviate the depression.”

Rhizoma Corydalis: nature and flavor: pungent, bitter, temperature.Return liver, spleen channel.Function cures mainly: invigorate blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.Lei Gong's Treatise on Preparation and Broiling of Materia Medica: " control pained for extremely." " Japan hanako materia medica ": " except wind, control gas, warm waist knee joint, broken disease addiction, flutter damage blood stasis, fall tire, and sudden and violent lumbago." " Kaibao Bencao ": " and main removing blood stasis, puerperal all diseases, because of the blood person of doing.Married woman's menoxenia, lumps in abdomen, and metrorrhagia drenches dew, and puerperal, blood was transported, and sudden and violent blood rushes to, and because damaging hematochezia, or wine rubs and boils clothes." " medicine origin ": " control that taste are depressed stagnantly not to fall apart, main asthenia cold diarrhea, cardiac and abdominal pain, the therapeutic method to keep the adverse QI flowing downwards helps digestion." " detailed outline ": " and invigorate blood circulation, promoting the circulation of QI, pain relieving, diuresis.”

Radix Salviae Miltiorrhizae: nature and flavor: bitter, is slightly cold.GUIXIN, Liver Channel.Function cures mainly: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, and clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris." herbal classic ": " main trusted subordinate's pathogen, borborygmus are faint as leaked water, and cold and heat gather; Broken disease, except abdominal mass, stops stuffy sensation with restlessness, QI invigorating." " WU Pu Bencao ": " control cardiac and abdominal pain." " not Lu ": " nourish blood, remove trusted subordinate's obstinate disease stagnation of QI, stiffness along the spinal column, foot numbness; Exorcising stays heat, takes sharp people for a long time." " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " reinforcing the heart sedate, calming heart and tranquilizing mind.Control forgetful punching seized with terror, palpitation with fear is insomnia." " detailed outline ": " and invigorate blood circulation, logical percardium.Control colic." " choosing of Yunnan Chinese herbal medicine ": " promoting blood circulation to remove blood stasis, sedation-analgesia.Control menoxenia, dysmenorrhea, rheumatic arthralgia, metrorrhagia, spit blood, mastitis, carbuncle.”

Flos Carthami: nature and flavor: pungent, temperature.GUIXIN, Liver Channel.Function cures mainly: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.Tang Materia Medica: " control trismus and inability to speak, blood agglomeration, puerperal all diseases." " Kaibao Bencao ": " and blood fortune locked mouth after main product, in abdomen stagnant blood not to the utmost, angor, retention of dead fetus, and wine boils clothes.Also main diseases due to noxious agents produced by various parasites hematochezia." " book on Chinese herbal medicine covers bamboo fish trap ": " sore throat dysphagia is obstructed, smashes juice pharynx." " detailed outline ": " and invigorate blood circulation, moisturize, pain relieving, loose swollen, stimulate the menstrual flow.”

Hirudo: nature and flavor: salty, bitter, flat; Slightly poisonous.Return Liver Channel.Function cures mainly: removing blood stasis, and removing blood stasis stimulates the menstrual flow.For lump in the abdomen mass in the abdomen, blood stasis amenorrhea, injury from falling down." herbal classic ": " master closed by stagnant blood, blood stasis, the moon, and removing blood stasis abdominal mass is gathered, loss of fecundity, dredging water passages.”

Radix Glycyrrhizae: nature and flavor: sweet, flat.GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong." herbal classic ": " longue meat, times power, incised wound swells, removing toxic substances for main the five internal organs six mansion cold and heat pathogen, hard muscles and bones." " not Lu ": " warming the middle warmer and descending qi, stuffy sensation with restlessness is losed heart, and hinders dirty cough, quenches the thirst, qualcomm meridian, and sharp vim and vigour separate hundred poison of drug." " property of medicine opinion ": " in main abdomen, cold type of pain, controls infantile convulsion, except distention and fullness in the abdomen; Tonification the five internal organs; Make all poison of drug; Support kidney qi internal injury, make us cloudy (no) flaccidity; Housewife's human blood drop lumbago; Empty and frequent fever; Add and use it." " Japan hanako materia medica ": " peace soul determines soul.Mend five kinds of strain and seven kinds of impairment, all be deficient, palpitation with fear, unhappy, forgetful.Logical nine orifices, sharp hundred arteries and veins, beneficial intensive culture gas, strengthening bone and muscle, separates cold and hot.”

Chinese medicine prescription mechanism of the present invention is as follows:

Monarch drug: Radix Ginseng, Radix Codonopsis, Radix Pseudostellariae, Rhizoma Atractylodis Macrocephalae merit are with replenishing QI to invigorate the spleen; Gypsum Fibrosum, Rhizoma Anemarrhenae merit are with the heat of lung heat clearing stomach.

Ministerial drug: Rhizoma Atractylodis, the Rhizoma Pinelliae, Rhizoma Arisaematis, Succus Bambusae, Fructus Trichosanthis, Bulbus Fritillariae Thunbergii merit are with drying dampness to eliminate phlegm; Rhizoma Chuanxiong, Rhizoma Corydalis, Radix Salviae Miltiorrhizae, Flos Carthami merit are with blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia.Radix Rehmanniae, Radix Ophiopogonis merit to grow the moon of lung stomach; Semen oryzae sativae merit protects body fluid with stomach reinforcing; Radix Puerariae merit is with the lucid yang sending up promoting the production of body fluid to quench thirst.

Adjuvant drug: Hirudo merit, with removing blood stasis dredging collateral, strengthens blood circulation invigorating efficacies; Herba Pogostemonis merit to be fallen apart Tianjin with circulation of qi promoting of being amusing.

Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription is for making medicine.

Modern society, along with growth in the living standard, great changes will take place for the diet structure of our people, and the thick greasy product of delicious food proportion in the diet constantly increases.Delicious food savoury, mistake all can cause taste impaired addicted to tea wine and unsound dietetic life mode etc., strong fortune mistake department.Taste are deficient makes the biochemical weary source of qi-blood-body fluid first, and the heart is become homeless foster, and simultaneously, then the motive is also not enough for gas virtual loss, and disorder of QI then hyperamization is sick, and promoting the circulation of blood is unable, and to cause sering slow smooth, and the deficiency of vital energy can not be automorph, hollow and interiorly to move as throbbing with fear under the heart.Second make in phlegm-damp raw, turbid damp fills the air, upper illiteracy breast sun and cause breast sun and do not open up, as the pathogenesis of Zhong Jing " Medical Treasures of the Golden Chamber " " weak pulse at YANG and stringy pulse at YIN ", uncomfortable in chest, to breathe hard be do, and the turbid stagnating heart meridian of expectorant causes blockage of the cardiac vessels, and because expectorant causes the stasis of blood, then obstruction of qi in the chest and cardialgia is raw.

In addition, Chinese medicine thinks the long-term surfeit delicious food of intemperance of taking food, pure wine savoury, and pungent perfume (or spice) is dry, impairing the spleen and stomach, causes transporting and transforming function of the spleen and stomach dereliction of duty, accumulates, dryness-transformation impairment of body fluid in accumulated heat, and rapid digestion of food consumption liquid, sends out as quenching one's thirst." the strange sick opinion of Plain Questions " is said: " this fertile institute is sent out also, and this person must count the sweet and refreshing and many fertilizer of food also, and overeating greasy food bringing about internal heat, over-eating the food with sweet flavor bringing about abdominal distension, therefore its gas overflow, transfer to and quenching one's thirst.”

In sum, the many complication with diabetes of Treating Stable Angina Pectoris of Coronary Artery Disease patient, its cause of disease and eating and drinking without temperance in close relations, main pathogenesis is insufficiency of the spleen, and transporting and transforming function of the spleen and stomach is neglected one's duty, raw in phlegm-damp, phlegm and blood stasis, and blockage of the vessel is sent out as " thoracic obstruction "; And accumulate in phlegm-damp accumulated heat, dryness-transformation impairment of body fluid, rapid digestion of food consumption liquid, send out as " quenching one's thirst ", the many complication with diabetes of Treating Stable Angina Pectoris of Coronary Artery Disease patient are relevant with " insufficiency of the spleen, phlegm-damp, blood stasis, gastric heat " in a word.This research adopts the treating coronary disease with traditional Chinese medicine stable angina pectoris complication with diabetes patient for the treatment of coronary heart disease stable angina pectoris complication with diabetes of the present invention, in side, Radix Ginseng, Radix Codonopsis, Radix Pseudostellariae, Rhizoma Atractylodis Macrocephalae merit are with replenishing QI to invigorate the spleen, temper is good for, then transporting is got profit, phlegm-damp not life, temper is good in addition, biochemical source, the motive is filled, and the heart is foster to some extent; Rhizoma Atractylodis, the Rhizoma Pinelliae, Rhizoma Arisaematis, Succus Bambusae, Fructus Trichosanthis, Bulbus Fritillariae Thunbergii merit are with drying dampness to eliminate phlegm; Rhizoma Chuanxiong, Rhizoma Corydalis, Radix Salviae Miltiorrhizae, Flos Carthami merit are with blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia; Hirudo merit, with removing blood stasis dredging collateral, strengthens blood circulation invigorating efficacies; Gypsum Fibrosum, Rhizoma Anemarrhenae merit with the heat of lung heat clearing stomach, Radix Rehmanniae, Radix Ophiopogonis merit to grow the moon of lung stomach; Semen oryzae sativae merit protects body fluid with stomach reinforcing; Radix Puerariae merit is with the lucid yang sending up promoting the production of body fluid to quench thirst; Herba Pogostemonis merit to be fallen apart Tianjin with circulation of qi promoting of being amusing.Full side's compatibility is reasonable, and all medicines share, and plays replenishing QI to invigorate the spleen altogether, damp eliminating is reduced phlegm, blood circulation promoting and blood stasis dispelling, eliminating stomach-fire, and effect of YIN supplementing and fluids increasing, agrees with completely with the pathogenesis of Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes, and through clinical trial checking, clinical efficacy is remarkable.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.

Embodiment 1

Treat a Chinese medicine for Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes, each crude drug weight proportion is as follows:

Gypsum Fibrosum 20g, Rhizoma Anemarrhenae 9g, Radix Rehmanniae 12g, Radix Ophiopogonis 9g, Semen oryzae sativae 15g, Radix Puerariae 9g, Herba Pogostemonis 6g, Radix Ginseng 10g, Radix Codonopsis 15g, Radix Pseudostellariae 15g, Rhizoma Atractylodis Macrocephalae 12g, Rhizoma Atractylodis 9g, Rhizoma Pinelliae 9g, Rhizoma Arisaematis 9g, Succus Bambusae 20g, Fructus Trichosanthis 10g, Bulbus Fritillariae Thunbergii 9g, Rhizoma Chuanxiong 9g, Rhizoma Corydalis 9g, Radix Salviae Miltiorrhizae 9g, Flos Carthami 9g, Hirudo 3g, Radix Glycyrrhizae 6g.

Embodiment 2

Treat a Chinese medicine for Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes, each crude drug weight proportion is as follows:

Gypsum Fibrosum 18g, Rhizoma Anemarrhenae 11g, Radix Rehmanniae 10g, Radix Ophiopogonis 11g, Semen oryzae sativae 13g, Radix Puerariae 11g, Herba Pogostemonis 5g, Radix Ginseng 8g, Radix Codonopsis 17g, Radix Pseudostellariae 13g, Rhizoma Atractylodis Macrocephalae 14g, Rhizoma Atractylodis 7g, Rhizoma Pinelliae 11g, Rhizoma Arisaematis 7g, Succus Bambusae 22g, Fructus Trichosanthis 8g, Bulbus Fritillariae Thunbergii 11g, Rhizoma Chuanxiong 7g, Rhizoma Corydalis 11g, Radix Salviae Miltiorrhizae 7g, Flos Carthami 11g, Hirudo 2g, Radix Glycyrrhizae 7g.

Embodiment 3

Treat a Chinese medicine for Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes, each crude drug weight proportion is as follows:

Gypsum Fibrosum 22g, Rhizoma Anemarrhenae 7g, Radix Rehmanniae 14g, Radix Ophiopogonis 7g, Semen oryzae sativae 17g, Radix Puerariae 7g, Herba Pogostemonis 7g, Radix Ginseng 12g, Radix Codonopsis 13g, Radix Pseudostellariae 17g, Rhizoma Atractylodis Macrocephalae 10g, Rhizoma Atractylodis 11g, Rhizoma Pinelliae 7g, Rhizoma Arisaematis 11g, Succus Bambusae 18g, Fructus Trichosanthis 12g, Bulbus Fritillariae Thunbergii 7g, Rhizoma Chuanxiong 11g, Rhizoma Corydalis 7g, Radix Salviae Miltiorrhizae 11g, Flos Carthami 7g, Hirudo 4g, Radix Glycyrrhizae 5g.

Embodiment 4

Treat a Chinese medicine for Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes, each crude drug weight proportion is as follows:

Gypsum Fibrosum 16g, Rhizoma Anemarrhenae 13g, Radix Rehmanniae 8g, Radix Ophiopogonis 13g, Semen oryzae sativae 11g, Radix Puerariae 13g, Herba Pogostemonis 4g, Radix Ginseng 6g, Radix Codonopsis 19g, Radix Pseudostellariae 11g, Rhizoma Atractylodis Macrocephalae 16g, Rhizoma Atractylodis 5g, Rhizoma Pinelliae 13g, Rhizoma Arisaematis 5g, Succus Bambusae 24g, Fructus Trichosanthis 6g, Bulbus Fritillariae Thunbergii 13g, Rhizoma Chuanxiong 5g, Rhizoma Corydalis 13g, Radix Salviae Miltiorrhizae 5g, Flos Carthami 13g, Hirudo 1g, Radix Glycyrrhizae 8g.

Embodiment 5

Treat a Chinese medicine for Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes, each crude drug weight proportion is as follows:

Gypsum Fibrosum 24g, Rhizoma Anemarrhenae 5g, Radix Rehmanniae 16g, Radix Ophiopogonis 5g, Semen oryzae sativae 19g, Radix Puerariae 5g, Herba Pogostemonis 8g, Radix Ginseng 14g, Radix Codonopsis 11g, Radix Pseudostellariae 19g, Rhizoma Atractylodis Macrocephalae 8g, Rhizoma Atractylodis 13g, Rhizoma Pinelliae 5g, Rhizoma Arisaematis 13g, Succus Bambusae 16g, Fructus Trichosanthis 14g, Bulbus Fritillariae Thunbergii 5g, Rhizoma Chuanxiong 13g, Rhizoma Corydalis 5g, Radix Salviae Miltiorrhizae 13g, Flos Carthami 5g, Hirudo 5g, Radix Glycyrrhizae 4g.

Carried out clinical pharrnacokinetics test to the Chinese medicine of embodiments of the invention l, Details as Follows:

1.1 object of study

Choose 100 routine Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes patients.Inclusive criteria: (1) Treating Stable Angina Pectoris of Coronary Artery Disease diagnostic criteria meets " the chronic stable angina pectoris Clinics and Practices guide " that cardiovascular diseases branch of Chinese Medical Association formulates; Stable angina pectoris CCS classification: I ~ III grade; Dependent diagnostic standard during diabetes diagnosis meets " diagnostics "; Treating Stable Angina Pectoris of Coronary Artery Disease and diabetes tcm diagnosis meet " thoracic obstruction " and " quenching one's thirst " dependent diagnostic standard in " new Chinese medicine guideline of clinical investigations ": disease is seen: chest pain, uncomfortable in chest, breathe hard, lassitude and weak, cardiopalmus, spontaneous perspiration, polyphagia polyphagia, thirsty, frequent micturition, emaciated physique, be hard and dry, lip complexion or fingernail purple dark, yellow and greasy fur, hesitant pulse or knot, generation, urge; (2) 30 years old < age <70 year; (3) person that can complete exercise treadmill test; (4) this research is added voluntarily, and the person that signs Informed Consent Form;

Exclusion standard: (1) is admitted to hospital and unstable angina pectoris or myocardial infarction or operation on vessels of heart person are occurred in first 3 months; (2) merge heart other pathological changes, heart failure, the arrhythmia for the treatment of need be carried out; (3) electrocardio diagram: complete left bundle branch block, ST section force down >1.0mv, left ventricular hypertrophy, expectation syndrome or the ventricular pacemaking rhythm of the heart; Color Sonography shows Left Ventricular Ejection Fraction≤40%; (4) serious hepatic and kidney function obstacle, blood system and malignant tumor person is merged; (5) gestation or women breast-feeding their children; (6) the compliance difference such as mental sickness can not partner treatment and observation;

1.2 method

1.2.1 Therapeutic Method

The Chinese medicine for the treatment of coronary heart disease stable angina pectoris complication with diabetes of the present invention, prescription is as follows: Radix Ginseng 10g, Radix Codonopsis 15g, Radix Pseudostellariae 15g, Rhizoma Atractylodis Macrocephalae 12g, Rhizoma Atractylodis 9g, Rhizoma Pinelliae 9g, Rhizoma Arisaematis 9g, Succus Bambusae 20g, Fructus Trichosanthis 10g, Bulbus Fritillariae Thunbergii 9g, Rhizoma Chuanxiong 9g, Rhizoma Corydalis 9g, Radix Salviae Miltiorrhizae 9g, Flos Carthami 9g, Hirudo 3g, Gypsum Fibrosum 20g, Rhizoma Anemarrhenae 9g, Radix Rehmanniae 12g, Radix Ophiopogonis 9g, Semen oryzae sativae 15g, Radix Puerariae 9g, Herba Pogostemonis 6g, Radix Glycyrrhizae 6g; Be decocted in water for oral dose, every day potion, sooner or later sub-service.It was a course for the treatment of with 2 months.

1.2.2 observation index

Curative effect index:

(1) exercise treadmill test: in order to the improvement situation of evaluate patient exercise tolerance, test and complete by same doctor; Index comprises: motion total time, maximal workload, bring out ST section and move down the 0.1mv time, bring out that ST section moves down 0.1mv quantity of motion, maximum ST section drop-out value, reaches the target heart time, the rhythm of the heart, ST section move down the persistent period when reaching maximal workload.

(2) angina pectoris situation: angina pectoris attacks number of times, outbreak persistent period, pain degree, nitroglycerin consumption.

(3) blood sugar level: measure before and after treatment and play fasting glucose and 2 hours blood glucoses after the meal morning, gets the meansigma methods of measurement three times.

(4) TCM syndrome integration: TCM syndrome integration: primary symptom: chest pain, uncomfortable in chest, is respectively 0,2,4,6 point from light to heavy; Secondary disease: gas distending pain over the hypochondrium, breathe hard, purple dark, the tongue of lassitude and weak, indigestion and loss of appetite loose stool, cardiopalmus, spontaneous perspiration, lip complexion or fingernail in vain greasy, hesitant pulse or knot, generation, urge, be respectively 0,1,2,3 point from light to heavy.

(5) quality of life: adopt Seattle angina pectoris life quality scoring (SAQ) to evaluate quality of life, higher expression patients ' life quality of marking is better, and evaluative dimension comprises: body limitation of activity degree (PL), angina pectoris steady statue (AS), angina pectoris attacks situation (AF), disease cognitive degree (DP) and treatment satisfaction (TS).

Safety indexes: check routine blood test, routine urinalysis and hepatic and renal function before and after treatment, record adverse events.

1.2.3 the standard of curative effect evaluation:

About coronary heart disease TCM syndrome the standard of curative effect evaluation in reference " new Chinese medicine guideline of clinical investigations ":

Cure: after treatment, Clinical symptom and sign obviously improves, and TCM syndrome integration improves >90% before comparatively treating

Effective: after treatment, Clinical symptom and sign obviously improves, and TCM syndrome integration improves >70% before comparatively treating;

Effective: after treatment, clinical main story sign takes a turn for the better, and TCM syndrome integration comparatively treats improvement 30% ~ 70%.

Invalid: after treatment, clinical main story sign even increases the weight of without improvement, and TCM syndrome integration is comparatively treated and improved <30%.

Cure rate %=cures number of cases/total number of cases x100%; Total effective rate %=(healing+effective+effectively) number of cases/total number of cases x100%.

2. result

2.1 Treating Stable Angina Pectoris of Coronary Artery Diseases improve situation

After treatment patient motion total time, maximal workload, bring out ST section move down the 0.1mv time, bring out that ST section moves down 0.1mv quantity of motion, maximum ST section drop-out value, rhythm of the heart when reaching maximal workload, ST section move down the persistent period and reach the target heart time all comparatively treat before obviously improvement, difference has statistical significance (P<0.05); In table 1.

After treatment, patient obviously improves before all comparatively treating in angina pectoris attacks number of times, outbreak persistent period and nitroglycerin consumption, and difference has statistical significance (P<0.05), in table 2.

2.2 blood glucose improve situation

The fasting glucose of patient and 2 hours blood glucoses obviously reduction before all comparatively treating after the meal after treatment, difference has statistical significance (P<0.05), in table 3.

2.3 TCM syndrome curative effects

200 routine Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes patients cure 190 examples, effective 9 examples, effective 1 example, invalid 0 example, and cure rate 95.0%, total effective rate is respectively 99.5%.

2.4 quality of lifes improved situation

After treatment, every life quality scores of patient obviously improves before all comparatively treating, and difference has statistical significance (P<0.05), in table 4.

Claims (3)

1. treat a Chinese medicine for Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes, be made up of the raw material of Chinese medicine medicine of following weight portion:

Gypsum Fibrosum 16-24 part, Rhizoma Anemarrhenae 5-13 part, Radix Rehmanniae 8-16 part, Radix Ophiopogonis 5-13 part, Semen oryzae sativae 11-19 part, Radix Puerariae 5-13 part, Herba Pogostemonis 4-8 part, Radix Ginseng 6-14 part, Radix Codonopsis 11-19 part, Radix Pseudostellariae 11-19 part, Rhizoma Atractylodis Macrocephalae 8-16 part, Rhizoma Atractylodis 5-13 part, Rhizoma Pinelliae 5-13 part, Rhizoma Arisaematis 5-13 part, Succus Bambusae 16-24 part, Fructus Trichosanthis 6-14 part, Bulbus Fritillariae Thunbergii 5-13 part, Rhizoma Chuanxiong 5-13 part, Rhizoma Corydalis 5-13 part, Radix Salviae Miltiorrhizae 5-13 part, Flos Carthami 5-13 part, Hirudo 1-5 part, Radix Glycyrrhizae 4-8 part.

2. the Chinese medicine for the treatment of Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes according to claim 1, is characterized in that, is made up of the raw material of Chinese medicine medicine of following weight portion:

Gypsum Fibrosum 18-22 part, Rhizoma Anemarrhenae 7-11 part, Radix Rehmanniae 10-14 part, Radix Ophiopogonis 7-11 part, Semen oryzae sativae 13-17 part, Radix Puerariae 7-11 part, Herba Pogostemonis 5-7 part, Radix Ginseng 8-12 part, Radix Codonopsis 13-17 part, Radix Pseudostellariae 13-17 part, Rhizoma Atractylodis Macrocephalae 10-14 part, Rhizoma Atractylodis 7-11 part, Rhizoma Pinelliae 7-11 part, Rhizoma Arisaematis 7-11 part, Succus Bambusae 18-22 part, Fructus Trichosanthis 8-12 part, Bulbus Fritillariae Thunbergii 7-11 part, Rhizoma Chuanxiong 7-11 part, Rhizoma Corydalis 7-11 part, Radix Salviae Miltiorrhizae 7-11 part, Flos Carthami 7-11 part, Hirudo 2-4 part, Radix Glycyrrhizae 5-7 part.

3. the Chinese medicine for the treatment of Treating Stable Angina Pectoris of Coronary Artery Disease complication with diabetes according to claim 2, is characterized in that, is made up of the raw material of Chinese medicine medicine of following weight portion:

20 parts, Gypsum Fibrosum, the Rhizoma Anemarrhenae 9 parts, Radix Rehmanniae 12 parts, Radix Ophiopogonis 9 parts, Semen oryzae sativae 15 parts, Radix Puerariae 9 parts, Herba Pogostemonis 6 parts, Radix Ginseng 10 parts, Radix Codonopsis 15 parts, Radix Pseudostellariae 15 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, Rhizoma Atractylodis 9 parts, the Rhizoma Pinelliae 9 parts, Rhizoma Arisaematis 9 parts, Succus Bambusae 20 parts, Fructus Trichosanthis 10 parts, Bulbus Fritillariae Thunbergii 9 parts, Rhizoma Chuanxiong 9 parts, Rhizoma Corydalis 9 parts, Radix Salviae Miltiorrhizae 9 parts, 9 parts, Flos Carthami, Hirudo 3 parts, 6 parts, Radix Glycyrrhizae.