CN104906476A - Traditional Chinese medicine preparation for treating urticaria - Google Patents
Traditional Chinese medicine preparation for treating urticaria Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating urticaria and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 12-18 parts of cynanchum paniculatum, 10-16 parts of citrus aurantium, 7-12 parts of schizonepeta, 9-13 parts of clerodendron cyrtophyllum turcz, 11-15 parts of chimonanthus nitens, 8-13 parts of fragrant spicebush bark, 10-14 parts of radix polygonati officinalis, 7-11 parts of reboulia hemisphaerica, 10-15 parts of dandelion, 9-12 parts of redback chrismashush roots and leaves, 11-14 parts of Chinese ivy, 6-9 parts of periostracum cicada, 8-11 parts of radix stemonae, 9-14 parts of clerodendron bungei roots, 8-15 parts of radix clematidis, 10-13 parts of swamp mahogany leaves and 12-16 parts of polygonum orientale roots. The traditional Chinese medicine preparation is accurate in curative effect, and is capable of enhancing the auto-immunity, keeping the natural physiological performance of the organism in dynamic equilibrium, restoring the self-maintenance function of the skin and treating both symptoms and root causes; the urticaria is not easy to recur; and the toxic and side effects caused by oral administration of western medicine hormone for a long period of time and external application of ointments are avoided.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine preparation and method for making thereof for the treatment of urticaria.
Background technology
The urticaria traditional Chinese medical science is referred to as urticaria, welt etc., frequently occurs the red welt block of protuberance property and pruritus is more acute for its Clinical symptoms with skin.Because of its rapid onset, erythra is flickering, repeatedly occurs, therefore Traditional Chinese Medicine is referred to as urticaria.Doctor trained in Western medicine belongs to allergic disease, relevant with allergic constitution.Modern age Climate and Environment Variation, air pollution etc. increases the weight of day by day, widely use pesticide, antibiotic, the food additive of various composition and the sensitization of Drug abuse in ingesta, makes the sickness rate of primary disease have rising trend.Not resistance to because composing official report, from the beginning of being affection by exopathogenic cold-wind or wind heat visitor table, cause disharmony of nutrient QI with defensive QI, pathogen is strongly fragrant in space between skin and muscles, must not thoroughly reach outward, interior must not catharsis, therefore see welt, wind being YANG-pathogen benefaction and number becomes, therefore onset is hurried, flickering, skin lesion appearing without definite location, pathogenic heat are strongly fragrant in blood system, and blood hot air wind producing or pathogenic heat are burnt cloudy liquid, wind syndrome due to blood-deficiency then makes Relapse rate show effect, and delay is difficult.Or because of improper diet, dysfunction of the spleen in transportation, the stagnation of QI in inner or in have malnutrition due to parasitic infestation, again by ailment said due to cold or exposure and cause primary disease.In a word, caused by dialectical genus wind and cold, wind heat, heat in blood, insufficiency of the spleen, blood deficiency.Medicine typing: 1. wind and cold.Syndrome: welt color is light micro-red, and with extending part as women's head-ornaments, brothers attach most importance to, chance wind, cold rear erythra increase the weight of, and obtain Wen Zehuan, and the winter drags the summer gently, and corpulent tongue is light, and tongue is white, floating and tense pulse or slow.Control suitable expelling wind and cold, harmonizing yingfen and weifen.2. wind heat.Syndrome: morbidity is anxious poly-, and welt color is red, scorching hot, and heat is then acute, obtains cold, subtracts, with heating, laryngopharynx swelling and pain, red tongue with thin and yellow fur, floating and rapid pulse.Control the table that should pungently cool completely, expelling wind and clearing away heat.3. heat in blood.Syndrome: first feel skin burns scratchy, namely whipped after scratching welt or streak protuberance, grab and more rise, attach most importance to night, and vexed not peaceful when sending out, xerostomia thinks drink, red tongue uncoated tongue surface like a mirror, stringy and rolling pulse.Control suitable clearing away heat and cooling blood, wind-repellent itching-relieving.4. insufficiency of the spleen.Syndrome: welt is repeatedly sent out and do not healed, companion's coldness of the body and aversion to cold, and extremity are not warm, oppression sensation over the epigastrium and anorexia, and stomachache is just let out, pale tongue with white fur, and deep-thready pulse delays.Control suitable warming middle-JIAO and strengthening the spleen, harmonizing yingfen and weifen.5. blood deficiency.Syndrome: rubella recurrent exerbation, with the passing of time delay does not heal, and more than afternoon or night-time attack, or increase the weight of time tired, red tongue with a little fluid or pale tongue, deep-thready pulse.Control suitable nourishing YIN and benefiting blood, dispelling wind pathogens.
Application publication number CN 103784695 A(application number 201210558198.6) Chinese patent literature disclose a kind of Chinese herbal medicine for the treatment of urticaria: Radix Angelicae Sinensis 20-30 part; Radix Rehmanniae 30-40 part; Periostracum Cicadae 15-25 part; Rhizoma Anemarrhenae 20-30 part; Radix Sophorae Flavescentis 20-30 part; Semen Lini 15-25 part; Herba Schizonepetae 20-30 part; Rhizoma Atractylodis 30-40 part; 20-30 part energetically; Gypsum Fibrosum 30-40 part; Radix Glycyrrhizae 15-25 part; Caulis Akebiae 20-30 part; Folium Isatidis 15-25 part; Desmodiumtrilorumrr. 15-25 part; Radix Alangii 15-25 part; Sesarma dehaani H. Milne-Edwards. 15-25 part.Application publication number CN 103893624 A(application number 201410152556.2) Chinese patent literature disclose a kind of decoction for the treatment of urticaria, described decoction comprises the medicines such as Ramulus Cinnamomi, Herba Spirodelae, the Fructus Kochiae, Rhizoma Atractylodis (parched to brown), stir-fry SEMEN COICIS, Radix Saposhnikoviae, southern Flos Lonicerae, Herba Violae, Fructus Arctii, Fructus Forsythiae, Semen Plantaginis.Application publication number CN 103860700 A(application number 201210527245.0) Chinese patent literature disclose a kind of pure Chinese medicine composition for the treatment of urticaria, be prepared from by the raw material of following weight portion: Radix Angelicae Sinensis 8-12, Rhizoma Chuanxiong 8-12, Radix Paeoniae Rubra 12-18, Rhizoma Et Radix Notopterygii 8-12, Herba Schizonepetae 6-10, Radix Saposhnikoviae 4-8, Fructus Kochiae 12-18, Rhizoma Atractylodis 8-12, Cortex Dictamni 10-14, Radix Glycyrrhizae 4-8.
Western medical treatment, based on antiallergic and relief of symptoms, commonly uses the Claritins such as Calamine Lotion, oral loratadine, cetirizine.Doctor trained in Western medicine is cured the symptoms, not the disease, and its side effect is large, and easily recurs.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine preparation and method for making thereof for the treatment of urticaria.Determined curative effect of the present invention, can strengthen autoimmunity, and keep the dynamic equilibrium of body nature physiological property, recover skin oneself care action, treating both the principal and secondary aspects of a disease, not easily recurs, and avoids long-time oral western medicine hormone and the toxic and side effects caused by externally used paste.
Technical scheme of the present invention is:
Treat a Chinese medicine preparation for urticaria, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Cynanchi Paniculati 12-18, Citrus aurantium L. var. amara Engl. 10-16, Herba Schizonepetae 7-12, Radix Clerodenri Cyrtophylli 9-13, Chimonanthusn itens Oliv. 11-15, Lindera angustifolia Cheng 8-13, Rhizoma Polygonati Odorati 10-14, Reboulia hemisphaerica 7-11, Herba Taraxaci 10-15, Radix seu Folium Alchorneae trewioidis 9-12, Caulis Hederae Sinensis 11-14, Periostracum Cicadae 6-9, Radix Stemonae 8-11, Radix clerodendri bungei 9-14, Radix Clematidis 8-15, Folium Eucalypti Robustae 10-13, Herba Polygoni Orientalis root 12-16.
Treat a Chinese medicine preparation for urticaria, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Radix Cynanchi Paniculati 14-17, Citrus aurantium L. var. amara Engl. 12-15, Herba Schizonepetae 8-11, Radix Clerodenri Cyrtophylli 10-12, Chimonanthusn itens Oliv. 12-14, Lindera angustifolia Cheng 9-11, Rhizoma Polygonati Odorati 11-13, Reboulia hemisphaerica 8-10, Herba Taraxaci 11-13, Radix seu Folium Alchorneae trewioidis 10-11, Caulis Hederae Sinensis 12-13, Periostracum Cicadae 7-8, Radix Stemonae 9-10, Radix clerodendri bungei 10-12, Radix Clematidis 9-12, Folium Eucalypti Robustae 11-12, Herba Polygoni Orientalis root 13-15.
Treat a Chinese medicine preparation for urticaria, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: Radix Cynanchi Paniculati 16, Citrus aurantium L. var. amara Engl. 14, Herba Schizonepetae 10, Radix Clerodenri Cyrtophylli 11, Chimonanthusn itens Oliv. 13, Lindera angustifolia Cheng 10, Rhizoma Polygonati Odorati 12, Reboulia hemisphaerica 9, Herba Taraxaci 12, Radix seu Folium Alchorneae trewioidis 10.5, Caulis Hederae Sinensis 12.5, Periostracum Cicadae 7.5, the Radix Stemonae 9.5, Radix clerodendri bungei 11, Radix Clematidis 10, Folium Eucalypti Robustae 11.5, Herba Polygoni Orientalis root 14.
Present invention also offers the preparation method Chinese medicine preparation of aforementioned therapies urticaria being made pharmaceutically acceptable decoction, powder, granule and tablet.
The preparation method of described decoction is:
(1) by Radix clerodendri bungei pulverization, cross No. four sieves, add water, amount of water is 9.6-14 times (preferred amount of water is 12.5 times of Radix clerodendri bungei weight) of Radix clerodendri bungei weight, 75 DEG C of stirring in water bath lixiviates 3-5 hour (preferably 75 DEG C stirring in water bath lixiviate 4 hours), with the centrifugation of 3200-3800r/min (preferably with the centrifugation of 3500r/min), centrifugalize 12-18 minute (preferred centrifugalize 15 minutes), gets supernatant for subsequent use;
(2) all the other the 13 taste crude drug except Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv., Radix clerodendri bungei and Folium Eucalypti Robustae are put into marmite, add water, amount of water is 4.9-6.7 times (preferred amount of water is 5.6 times of the 13 taste crude drug gross weights added) of the 13 taste crude drug gross weights added, soak 1 hour, first boil with high heat to boiling, after turn slow fire boiling 38-55 minute (preferably then turn slow fire boiling 46 minutes), leach medicinal liquid;
(3) Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv. and Folium Eucalypti Robustae are joined fill in the marmite of medicinal residues, add water, amount of water is 2.8-4.5 times (preferred amount of water is 3.5 times of all crude drug gross weights added) of all crude drug gross weights added, first boil with high heat to boiling, after turn slow fire boiling 28-40 minute (preferably then turn slow fire boiling 32 minutes), leach medicinal liquid;
(4) step (1), step (2) and step (3) gained medicinal liquid are mixed, to obtain final product.
The preparation method of described powder is:
(1) by Radix clerodendri bungei pulverization, cross No. four sieves, add water, amount of water is 9.6-14 times (preferred amount of water is 12.5 times of Radix clerodendri bungei weight) of Radix clerodendri bungei weight, 75 DEG C of stirring in water bath lixiviates 3-5 hour (preferably 75 DEG C stirring in water bath lixiviate 4 hours), with the centrifugation of 3200-3800r/min (preferably with the centrifugation of 3500r/min), centrifugalize 12-18 minute (preferred centrifugalize 15 minutes), gets supernatant for subsequent use;
(2) all the other the 13 taste crude drug except Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv., Radix clerodendri bungei and Folium Eucalypti Robustae are put into marmite, add water, amount of water is 4.9-6.7 times (preferred amount of water is 5.6 times of the 13 taste crude drug gross weights added) of the 13 taste crude drug gross weights added, soak 1 hour, first boil with high heat to boiling, after turn slow fire boiling 38-55 minute (preferably then turn slow fire boiling 46 minutes), leach medicinal liquid;
(3) Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv. and Folium Eucalypti Robustae are joined fill in the marmite of medicinal residues, add water, amount of water is 2.8-4.5 times (preferred amount of water is 3.5 times of all crude drug gross weights added) of all crude drug gross weights added, first boil with high heat to boiling, after turn slow fire boiling 28-40 minute (preferably then turn slow fire boiling 32 minutes), leach medicinal liquid;
(4) step (1), step (2) and step (3) gained medicinal liquid are mixed, concentrating under reduced pressure become relative density be 1.35 thick paste, 50 DEG C of dryings 12 hours, are ground into fine powder, cross No. eight sieves, often to wrap 4g subpackage, sterile packaged and get final product.
The preparation method of described granule is:
(1) by Radix clerodendri bungei pulverization, cross No. four sieves, add water, amount of water is 9.6-14 times (preferred amount of water is 12.5 times of Radix clerodendri bungei weight) of Radix clerodendri bungei weight, 75 DEG C of stirring in water bath lixiviates 3-5 hour (preferably 75 DEG C stirring in water bath lixiviate 4 hours), with the centrifugation of 3200-3800r/min (preferably with the centrifugation of 3500r/min), centrifugalize 12-18 minute (preferred centrifugalize 15 minutes), gets supernatant for subsequent use;
(2) all the other the 13 taste crude drug except Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv., Radix clerodendri bungei and Folium Eucalypti Robustae are put into marmite, add water, amount of water is 4.9-6.7 times (preferred amount of water is 5.6 times of the 13 taste crude drug gross weights added) of the 13 taste crude drug gross weights added, soak 1 hour, first boil with high heat to boiling, after turn slow fire boiling 38-55 minute (preferably then turn slow fire boiling 46 minutes), leach medicinal liquid;
(3) Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv. and Folium Eucalypti Robustae are joined fill in the marmite of medicinal residues, add water, amount of water is 2.8-4.5 times (preferred amount of water is 3.5 times of all crude drug gross weights added) of all crude drug gross weights added, first boil with high heat to boiling, after turn slow fire boiling 28-40 minute (preferably then turn slow fire boiling 32 minutes), leach medicinal liquid;
(4) step (1), step (2) and step (3) gained medicinal liquid are mixed, concentrating under reduced pressure become relative density be 1.35 thick paste, add sucrose, the weight of sucrose is the weight of the 1/3-3/5(preferably sucrose of gained thick paste gross weight is 1/2 of gained thick paste gross weight), mixing, make granule, 55 DEG C of dryings 10 hours, to obtain final product.
The preparation method of described tablet is:
(1) by Radix clerodendri bungei pulverization, cross No. four sieves, add water, amount of water is 9.6-14 times (preferred amount of water is 12.5 times of Radix clerodendri bungei weight) of Radix clerodendri bungei weight, 75 DEG C of stirring in water bath lixiviates 3-5 hour (preferably 75 DEG C stirring in water bath lixiviate 4 hours), with the centrifugation of 3200-3800r/min (preferably with the centrifugation of 3500r/min), centrifugalize 12-18 minute (preferred centrifugalize 15 minutes), gets supernatant for subsequent use;
(2) all the other the 13 taste crude drug except Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv., Radix clerodendri bungei and Folium Eucalypti Robustae are put into marmite, add water, amount of water is 4.9-6.7 times (preferred amount of water is 5.6 times of the 13 taste crude drug gross weights added) of the 13 taste crude drug gross weights added, soak 1 hour, first boil with high heat to boiling, after turn slow fire boiling 38-55 minute (preferably then turn slow fire boiling 46 minutes), leach medicinal liquid;
(3) Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv. and Folium Eucalypti Robustae are joined fill in the marmite of medicinal residues, add water, amount of water is 2.8-4.5 times (preferred amount of water is 3.5 times of all crude drug gross weights added) of all crude drug gross weights added, first boil with high heat to boiling, after turn slow fire boiling 28-40 minute (preferably then turn slow fire boiling 32 minutes), leach medicinal liquid;
(4) step (1), step (2) and step (3) gained medicinal liquid are mixed, concentrating under reduced pressure become relative density be 1.35 thick paste, add sucrose, the weight of sucrose is the weight of the 1/3-3/5(preferably sucrose of gained thick paste gross weight is 1/2 of gained thick paste gross weight), mixing, makes granule, 55 DEG C of dryings 10 hours, tabletting, the heavy 0.5g of every sheet, to obtain final product.
Chinese medicine preparation scientific formula provided by the invention, the preparation method of various dosage form is simple, products obtained therefrom taking convenience.In addition, excellent results of the present invention also shows:
1, determined curative effect;
2, there is expelling wind and cold, clearing away heat and cooling blood, circulation of qi promoting spleen invigorating, stomach function regulating preventing or arresting vomiting, nourishing YIN and moistening the lung, dispelling wind and heat pathogens, rash only
The effect of itching, can strengthen autoimmunity, and keep the dynamic equilibrium of body nature physiological property, recover skin oneself care action, treating both the principal and secondary aspects of a disease, not easily recurs;
3, long-time oral western medicine hormone and the toxic and side effects caused by externally used paste is avoided;
4, medicine source is easy to get, and cheap.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1treat a Chinese medicine preparation for urticaria, the primary raw material medicine getting following weight parts is prepared from (every part is 480g): Radix Cynanchi Paniculati 12 parts, Citrus aurantium L. var. amara Engl. 10 parts, Herba Schizonepetae 7 parts, Radix Clerodenri Cyrtophylli 9 parts, Chimonanthusn itens Oliv. 11 parts, Lindera angustifolia Cheng 8 parts, Rhizoma Polygonati Odorati 10 parts, Reboulia hemisphaerica 7 parts, Herba Taraxaci 10 parts, Radix seu Folium Alchorneae trewioidis 9 parts, Caulis Hederae Sinensis 11 parts, Periostracum Cicadae 6 parts, the Radix Stemonae 8 parts, Radix clerodendri bungei 9 parts, Radix Clematidis 8 parts, Folium Eucalypti Robustae 10 parts, Herba Polygoni Orientalis root 12 parts.
The preparation method of the Chinese medicine preparation decoction of above-mentioned treatment urticaria is:
(1) by Radix clerodendri bungei pulverization, cross No. four sieves, add water, amount of water is 9.6 times of Radix clerodendri bungei weight, 75 DEG C of stirring in water bath lixiviates 3 hours, and with the centrifugation of 3200r/min, centrifugalize 12 minutes, gets supernatant for subsequent use;
(2) all the other the 13 taste crude drug except Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv., Radix clerodendri bungei and Folium Eucalypti Robustae are put into marmite, add water, amount of water is 4.9 times of the 13 taste crude drug gross weights added, soak 1 hour, first boil with high heat to boiling, after turn slow fire boiling 38 minutes, leach medicinal liquid;
(3) Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv. and Folium Eucalypti Robustae are joined and fill in the marmite of medicinal residues, add water, amount of water is 2.8 times of all crude drug gross weights added, and first boils with high heat to boiling, after turn slow fire boiling 28 minutes, leach medicinal liquid;
(4) step (1), step (2) and step (3) gained medicinal liquid are mixed, to obtain final product.
The instructions of taking of the Chinese medicine preparation decoction of gained treatment urticaria of the present invention is: oral, twice on the one, and a 170mL is warm.
embodiment 2treat a Chinese medicine preparation for urticaria, the primary raw material medicine getting following weight parts is prepared from (every part is 480g): Radix Cynanchi Paniculati 18 parts, Citrus aurantium L. var. amara Engl. 16 parts, Herba Schizonepetae 12 parts, Radix Clerodenri Cyrtophylli 13 parts, Chimonanthusn itens Oliv. 15 parts, Lindera angustifolia Cheng 13 parts, Rhizoma Polygonati Odorati 14 parts, Reboulia hemisphaerica 11 parts, Herba Taraxaci 15 parts, Radix seu Folium Alchorneae trewioidis 12 parts, Caulis Hederae Sinensis 14 parts, Periostracum Cicadae 9 parts, the Radix Stemonae 11 parts, Radix clerodendri bungei 14 parts, Radix Clematidis 15 parts, Folium Eucalypti Robustae 13 parts, Herba Polygoni Orientalis root 16 parts.
The preparation method of the Chinese medicine preparation powder of above-mentioned treatment urticaria is:
(1) by Radix clerodendri bungei pulverization, cross No. four sieves, add water, amount of water is 12.5 times of Radix clerodendri bungei weight, 75 DEG C of stirring in water bath lixiviates 4 hours, and with the centrifugation of 3500r/min, centrifugalize 15 minutes, gets supernatant for subsequent use;
(2) all the other the 13 taste crude drug except Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv., Radix clerodendri bungei and Folium Eucalypti Robustae are put into marmite, add water, amount of water is 5.6 times of the 13 taste crude drug gross weights added, soak 1 hour, first boil with high heat to boiling, after turn slow fire boiling 46 minutes, leach medicinal liquid;
(3) Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv. and Folium Eucalypti Robustae are joined and fill in the marmite of medicinal residues, add water, amount of water is 3.5 times of all crude drug gross weights added, and first boils with high heat to boiling, after turn slow fire boiling 32 minutes, leach medicinal liquid;
(4) step (1), step (2) and step (3) gained medicinal liquid are mixed, concentrating under reduced pressure become relative density be 1.35 thick paste, 50 DEG C of dryings 12 hours, are ground into fine powder, cross No. eight sieves, often to wrap 4g subpackage, sterile packaged and get final product.
model case one:liu XX, female, 37 years old.Before 9 months, patient starts whole body and works the light red welt that differs in size, with face and hand the most serious, once took the Drug therapys such as chlorphenamine, heavy time light during the state of an illness.On May 13rd, 2010 examines.Examine and see that patient's welt color is light micro-red, attach most importance to face and hand hands, with dyspepsia, thirsty, the symptoms such as stool amount is few, oliguria with reddish urine, lumbago, weak.Corpulent tongue is light, and tongue is white, and slow pulse delays.Be diagnosed as urticaria.Take the Chinese medicine preparation powder of the present embodiment gained treatment urticaria, one day twice, each 4g, boiled water was taken after mixing it with water.Take 1 week, above-mentioned symptom is clearly better.Continue to take 1 week sky, welt disappears, clinical symptom disappearance.Follow up a case by regular visits to and do not recur.
embodiment 3treat a Chinese medicine preparation for urticaria, the primary raw material medicine getting following weight parts is prepared from (every part is 480g): Radix Cynanchi Paniculati 14 parts, Citrus aurantium L. var. amara Engl. 12 parts, Herba Schizonepetae 8 parts, Radix Clerodenri Cyrtophylli 10 parts, Chimonanthusn itens Oliv. 12 parts, Lindera angustifolia Cheng 9 parts, Rhizoma Polygonati Odorati 11 parts, Reboulia hemisphaerica 8 parts, Herba Taraxaci 11 parts, Radix seu Folium Alchorneae trewioidis 10 parts, Caulis Hederae Sinensis 12 parts, Periostracum Cicadae 7 parts, the Radix Stemonae 9 parts, Radix clerodendri bungei 10 parts, Radix Clematidis 9 parts, Folium Eucalypti Robustae 11 parts, Herba Polygoni Orientalis root 13 parts.
The preparation method of the Chinese medicine preparation granule of above-mentioned treatment urticaria is:
(1) by Radix clerodendri bungei pulverization, cross No. four sieves, add water, amount of water is 12.5 times of Radix clerodendri bungei weight, 75 DEG C of stirring in water bath lixiviates 4 hours, and with the centrifugation of 3500r/min, centrifugalize 15 minutes, gets supernatant for subsequent use;
(2) all the other the 13 taste crude drug except Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv., Radix clerodendri bungei and Folium Eucalypti Robustae are put into marmite, add water, amount of water is 5.6 times of the 13 taste crude drug gross weights added, soak 1 hour, first boil with high heat to boiling, after turn slow fire boiling 46 minutes, leach medicinal liquid;
(3) Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv. and Folium Eucalypti Robustae are joined and fill in the marmite of medicinal residues, add water, amount of water is 3.5 times of all crude drug gross weights added, and first boils with high heat to boiling, after turn slow fire boiling 32 minutes, leach medicinal liquid;
(4) step (1), step (2) and step (3) gained medicinal liquid are mixed, concentrating under reduced pressure become relative density be 1.35 thick paste, add sucrose, the weight of sucrose is 1/2 of gained thick paste gross weight, and mixing, makes granule, and 55 DEG C of dryings 10 hours, to obtain final product.
model case two:yao XX, man, 22 years old.Main suit: urticaria more than 2 years.Before 2 years, patient starts to occur the red speckle of whole body welt shape, itches very.Once used multi-medicament treatment, but cured the symptoms, not the disease, repeatedly sent out.On June 8th, 2011 examines.The red speckle of entire patient's welt shape, companion's coldness of the body and aversion to cold, extremity are not warm, and stomachache is just let out.Pale tongue with white fur, deep-thready pulse delays.Be diagnosed as urticaria.Take the Chinese medicine preparation granule of the present embodiment gained treatment urticaria, one day twice, each 10g, boiled water was taken after mixing it with water.Take 5 days, only itch, speckle reduces.Continue to take 5 days, all diseases disappear.Follow up a case by regular visits to without recurrence.
embodiment 4treat a Chinese medicine preparation for urticaria, the primary raw material medicine getting following weight parts is prepared from (every part is 480g): Radix Cynanchi Paniculati 17 parts, Citrus aurantium L. var. amara Engl. 15 parts, Herba Schizonepetae 11 parts, Radix Clerodenri Cyrtophylli 12 parts, Chimonanthusn itens Oliv. 14 parts, Lindera angustifolia Cheng 11 parts, Rhizoma Polygonati Odorati 13 parts, Reboulia hemisphaerica 10 parts, Herba Taraxaci 13 parts, Radix seu Folium Alchorneae trewioidis 11 parts, Caulis Hederae Sinensis 13 parts, Periostracum Cicadae 8 parts, the Radix Stemonae 10 parts, Radix clerodendri bungei 12 parts, Radix Clematidis 12 parts, Folium Eucalypti Robustae 12 parts, Herba Polygoni Orientalis root 15 parts.
The preparation method of the Chinese medicine preparation tablet of above-mentioned treatment urticaria is:
(1) by Radix clerodendri bungei pulverization, cross No. four sieves, add water, amount of water is 12.5 times of Radix clerodendri bungei weight, 75 DEG C of stirring in water bath lixiviates 4 hours, and with the centrifugation of 3500r/min, centrifugalize 15 minutes, gets supernatant for subsequent use;
(2) all the other the 13 taste crude drug except Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv., Radix clerodendri bungei and Folium Eucalypti Robustae are put into marmite, add water, amount of water is 5.6 times of the 13 taste crude drug gross weights added, soak 1 hour, first boil with high heat to boiling, after turn slow fire boiling 46 minutes, leach medicinal liquid;
(3) Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv. and Folium Eucalypti Robustae are joined and fill in the marmite of medicinal residues, add water, amount of water is 3.5 times of all crude drug gross weights added, and first boils with high heat to boiling, after turn slow fire boiling 32 minutes, leach medicinal liquid;
(4) by step (1), step (2) and step (3) gained medicinal liquid mix, concentrating under reduced pressure become relative density be 1.35 thick paste, add sucrose, the weight of sucrose is 1/2 of gained thick paste gross weight, mixing, makes granule, 55 DEG C of dryings 10 hours, tabletting, the heavy 0.5g of every sheet, to obtain final product.
model case three:sieve XX, female, 40 years old.Main suit: suffer from urticaria more than 10 years, increase the weight of 3 years.Before 10 years, there is welt in entire patient, and annual outbreak once, is taken medicine and namely healed soon.Over nearly 3 years, outbreak is frequent, monthly, during outbreak, unable with body, pain in the lumbar region.Take multi-medicament treatment, have no improvement.On March 18th, 2011 examines.Examine and see that entire patient is dispersed in welt as seen, color is lighter.Moderate pulse is sliding, light red tongue, white and thin fur.Be diagnosed as urticaria.Take the Chinese medicine preparation tablet of the present embodiment gained treatment urticaria, one day twice, each 4, warm water took.Take two weeks, welt disappears, and all diseases disappear.Follow up a case by regular visits to without recurrence.
embodiment 5treat a Chinese medicine preparation for urticaria, the primary raw material medicine getting following weight parts is prepared from (every part is 480g): Radix Cynanchi Paniculati 16 parts, Citrus aurantium L. var. amara Engl. 14 parts, Herba Schizonepetae 10 parts, Radix Clerodenri Cyrtophylli 11 parts, Chimonanthusn itens Oliv. 13 parts, Lindera angustifolia Cheng 10 parts, Rhizoma Polygonati Odorati 12 parts, Reboulia hemisphaerica 9 parts, Herba Taraxaci 12 parts, Radix seu Folium Alchorneae trewioidis 10.5 parts, Caulis Hederae Sinensis 12.5 parts, Periostracum Cicadae 7.5 parts, the Radix Stemonae 9.5 parts, Radix clerodendri bungei 11 parts, Radix Clematidis 10 parts, Folium Eucalypti Robustae 11.5 parts, Herba Polygoni Orientalis root 14 parts.
The preparation method of the Chinese medicine preparation decoction of above-mentioned treatment urticaria is:
(1) by Radix clerodendri bungei pulverization, cross No. four sieves, add water, amount of water is 12.5 times of Radix clerodendri bungei weight, 75 DEG C of stirring in water bath lixiviates 4 hours, and with the centrifugation of 3500r/min, centrifugalize 15 minutes, gets supernatant for subsequent use;
(2) all the other the 13 taste crude drug except Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv., Radix clerodendri bungei and Folium Eucalypti Robustae are put into marmite, add water, amount of water is 5.6 times of the 13 taste crude drug gross weights added, soak 1 hour, first boil with high heat to boiling, after turn slow fire boiling 46 minutes, leach medicinal liquid;
(3) Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv. and Folium Eucalypti Robustae are joined and fill in the marmite of medicinal residues, add water, amount of water is 3.5 times of all crude drug gross weights added, and first boils with high heat to boiling, after turn slow fire boiling 32 minutes, leach medicinal liquid;
(4) step (1), step (2) and step (3) gained medicinal liquid are mixed, to obtain final product.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Radix Cynanchi Paniculati: base is former: be root and rhizome or the whole herb with root of asclepiadaceae plant Radix Cynanchi Paniculati.Chemical composition: herb is about l% containing paeonol.Find out again and sarcostin, the material going to phenol cynanchogenin, fine hair milk rattan glycoside unit very similar with going to acyl trailing plants glycoside unit and acetic acid, cinnamic acid etc.Root is containing flavonoid glycoside, saccharide, aminoacid, paeonol.Containing C21 steroid.Contain sarcostin in hydrolyzate, remove acetyl periplogenin, remove acetyl cynanchogenin and hold in the palm graceful glycoside unit, still containing D-cymarose, D-2-desoxy-D-altromethylose, L-oleandrose and D-sarmentose.Report is separately had to be out of shape steroid glycoside compound containing C21, the Radix Cynanchi Paniculati glycoside A become with different sugar chain by glaucogenin D, the Radix Cynanchi Atrati glycoside B that B, C and glaucogenin B are formed.In addition containing paeonol, different paeonol, stearic acid ester in the last of the ten Heavenly stems, melissane, hexadecylene, cupreol and D-subconjunctival capillaries grass alcohol.The property of medicine: pungent, temperature.1. " herbal classic ": " acrid in the mouth, temperature." 2. " not Lu ": " nontoxic." function cures mainly: analgesia, cough-relieving, inducing diuresis to remove edema, promoting blood circulation and detoxication.Treat for stomachache, toothache, rheumatalgia, abdominal pain in menstruation, chronic tracheitis, ascites, edema, dysentery, enteritis, traumatic injury, eczema, urticaria, venom.
Citrus aurantium L. var. amara Engl.: base is former: be the alabastrum of rutaceae Citrus aurantium L. var. amara Engl..The property of medicine: pungent; Sweet; Micro-hardship; Property is put down.Function cures mainly: the chest stuffiness relieving of regulating the flow of vital energy, stomach function regulating preventing or arresting vomiting.Main painful abdominal mass is vexed in the heart, abdominal distention, anorexia, nausea and vomiting.
Herba Schizonepetae: base is former: be stem and leaf and the spica of lip section plant Schizonepeta tenuifolia and many lobed leaf Herba Schizonepetae.The property of medicine: pungent, micro-hardship, micro-wet.Return lung, Liver Channel.Function cures mainly: dispel the wind, and induces sweat, rash, hemostasis.Main cold, fever, headache, eye itching, cough, laryngopharynx swelling and pain, measles, carbuncle, skin ulcer scabies, epistaxis, spits blood, has blood in stool, metrorrhagia, puerperal blood faints.
Radix Clerodenri Cyrtophylli: base is former: be the root of dicotyledon medicine Verbenaceae Herba Diclipterae Chinensis.The property of medicine: bitter; Cold.GUIXIN, Liver Channel.Function cures mainly: heat clearing away, removing toxic substances, removing heat from blood.Main encephalitis b, epidemic encephalitis, the high heat of flu, epidemic encephalitis, parotitis, heat in blood sends out class, measles pneumonia, and icteric tripe is scorching, diarrhea of heat type hematodiarrhoea, beriberoid pyretic arthralgia, headache, laryngopharynx swelling and pain, acute toothache, orchitis.
Chimonanthusn itens Oliv.: base is former: be the leaf of Calycanthaceae Chimonanthusn itens Oliv..The property of medicine: acrid in the mouth; Micro-hardship; Warm in nature.Return lung, spleen channel.Function cures mainly: expelling pathogenic wind from the body surface, removing dampness by means of aromatics.Main flow sense, heatstroke, chronic bronchitis, wet tired uncomfortable in chest, ant bites mosquito.
Lindera angustifolia Cheng: base is former: be root or the branch and leaf of canella Ramulus et Folium Linderae Angustifoliae.The property of medicine: pungent, temperature.Function cures mainly: dispel the wind, dehumidifying, circulation of qi promoting cold expelling, removing toxic substances and promoting subsidence of swelling.Main anemofrigid cold, headache, rheumatic arthralgia, numb limbs and tense tendons, dysentery, enteritis, traumatic injury, sore swollen toxin, urticaria, tuberculous lymphadenitis.
Rhizoma Polygonati Odorati: base is former: be the rhizome of liliaceous plant Rhizoma Polygonati Odorati.The property of medicine: sweet, flat.Attach to the lung and stomach meridians.Function cures mainly: nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid.Main cough caused by dryness, chronic cough, the dry throat and mouth of calentura cloudy liquid consumption wound, interior-heat is quenched one's thirst, deficiency of YIN diseases caused by exogenous pathogenic factor, dizzy dizzy, muscle arteries and veins spasm and pain.
Reboulia hemisphaerica: base is former: be the thallus of Liu Guan tongue section (Reboulia hemisphaerica section) phytobezoar marchantia.The property of medicine: light; Puckery; Cool.Function cures mainly: heat-clearing and toxic substances removing, detumescence hemostasis.Main furuncle toxic swelling, burn and scald, treating swelling and pain by traumatic injury, traumatic hemorrhage.
Herba Taraxaci: base is former: for feverfew Herba Taraxaci, alkali ground Herba Taraxaci, Herba Taraxaci ohwiani, different luxuriant Herba Taraxaci, Taraxacum asiatica Dahlst, Taraxacum erythropodium Kifag etc. belong to the herb of various plants together.The property of medicine: bitter in the mouth, sweet, cold in nature.Return liver, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.Main acute mastitis, lung abscess, acute appendicitis, mumps, furuncle carbuncle toxin, conjunctival congestion and swelling pain, cold, fever, cough, laryngopharynx swelling and pain, stomach-fire, enteritis, dysentery, hepatitis, gallbladder frightens inflammation, urinary tract infection, snake bite and insect sting.
Radix seu Folium Alchorneae trewioidis: base is former: be the Ye Jigen of the red back of the body Cortex Alchorneae Davidii of euphorbia plant.The property of medicine: sweet; Cool.Return bladder, large intestine, lung meridian.Function cures mainly: clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, killing parasites for relieving itching.Main dysentery, pyretic stranguria, stranguria caused by urinary stone, hematuria, metrorrhagia, leukorrhagia, rubella, eczema, scabies, caries pain, decubital ulcer.
Caulis Hederae Sinensis: base is former: be the stem and leaf of Araliaceae Caulis Hederae Sinensis.The property of medicine: acrid in the mouth; Bitter; Property is put down.Return liver, spleen, lung meridian.Function cures mainly: dispel the wind, dampness removing, suppressing the hyperactive liver, removing toxic substances.Main air pain of dampness syndrome, paralysis, mouth eye is oblique, epistaxis, menoxenia, traumatic injury, laryngopharynx swelling and pain, furuncle furuncle carbuncle, hepatitis, snake bite and insect sting.
Periostracum Cicadae: base is former: exuviae shell when the larva for cicada Cryptotympana atrata Fabr. sprouts wings.The property of medicine: sweet, cold.Return lung, Liver Channel.Function cures mainly: have dispelling wind and heat pathogens, sore-throat relieving, rash, improving acuity of vision and removing nebula, effect of spasmolytic.For anemopyretic cold, pharyngalgia hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus.
The Radix Stemonae: base is former: be the root of Stemonaceae plant Radix Stemonae, Radix stemonae japonicae and radix stemonae tuberosae.The property of medicine: sweet; Bitter; Tepor.Return lung meridian.Function cures mainly: nourishing the lung to arrest cough, parasite killing delousing.Main new chronic cough is coughed, pulmonary tuberculosis, pertussis, enterobiasis, body louse, tinea scabies.
Radix clerodendri bungei: base is former: be the root of dicotyledon medicine Verbenaceae Caulis et folium clerodendri bungei.The property of medicine: pungent, bitter; Temperature.Return liver,spleen,kidney, lung meridian.Function cures mainly: circulation of qi promoting spleen invigorating, expelling wind and removing dampness, removing toxic substances and promoting subsidence of swelling, blood pressure lowering.The stagnant abdominal distention of staple food, dizzy, hiss and cough, outer dysentery proctoptosis, perianal abscess hematochezia, stranguria with turbid discharge leukorrhagia, rheumatalgia, beriberi, swollen ulcer drug, dermatitis rhus, hypertension.
Radix Clematidis: base is former: be the root of cohosh Radix Clematidis.The property of medicine: pungent, salty, temperature, poisonous.Return urinary bladder channel.Function cures mainly: wind-damp dispelling, the meridian dredging, expectorant saliva, the loose hypochondriac lump.Control gout, insensitive impediment, chills and pain of the waist and kness, beriberi, malaria, lump in the abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat pharynxs.
Folium Eucalypti Robustae: base is former: be the leaf of myrtle Folium Eucalypti Robustae.The property of medicine: acrid in the mouth, bitter, cool in nature.Function cures mainly: dispelling wind is delivered, expelling phlegm for arresting cough, heat-clearing and toxic substances removing, killing parasites for relieving itching.Main flu, high heat closes pain, dyspnea and cough due to lung-heat, and dysentery is suffered from abdominal pain, malaria, rheumatic arthralgia, filaricide, leptospirosis, laryngopharynx swelling and pain, conjunctival congestion, cataracta, boil of the external auditory meatus, erysipelas, carbuncle, acute mastitis, measles, rubella, eczema, scabies, scalds.
Herba Polygoni Orientalis root: base is former: be the rhizome of polygonaceae plant Polygonum knotweed.The property of medicine: pungent, cool in nature, poisonous.Function cures mainly: heat-clearing and toxic substances removing, eliminating dampness and dredging channels, promoting tissue regeneration and ulcer healing.Main dysentery, enteritis, edema, beriberi, rheumatic arthralgia, traumatic injury, urticaria, sore, carbuncle and painful swelling or of a specified duration bursting are not held back.
test example 1the clinical practice of the Chinese medicine preparation (embodiment 5) of gained of the present invention treatment urticaria: in January, 2010 in December ,-2011, screen 310 routine urticaria patients in 6 hospitals.Be divided into two groups at random, experimental group and matched group.Experimental group male 85 example, women 70 example, oldest 68 years old, minimum 15 years old of age, 37 years old mean age, the course of disease 5 months-12 years.Matched group male 85 example, women 70 example, oldest 68 years old, minimum 15 years old of age, 37 years old mean age, the course of disease 5 months-12 years.The physical data no significant difference such as two groups of case sexes, age, courses of disease, have comparability (P > 0.05).
Therapeutic Method: experimental group uses gained of the present invention to treat the Chinese medicine preparation of urticaria, using method: oral, twice on the one, a 170mL, warm, 7 days is a course for the treatment of.Matched group uses the medicine (example hydrochloric acid cetirizine sheet, acrivastine capsule, chlorpheniramine maleate tablets etc.) of conventional therapy urticaria, within 7 days, is a course for the treatment of.After two groups of patients all treat two courses for the treatment of, carry out Comparison of therapeutic.
Curative effect situation criterion: recovery from illness: welt disappears, pruritus disappears, and clinical symptom disappearance, visits and do not recur; Take a turn for the better: welt disappears more than 50%, and pruritis alleviates, outbreak interval extends; Invalid: sign, subjective symptoms are all not improved.Table 1: the Chinese medicine preparation compliance test result of gained treatment urticaria of the present invention
Efficacy analysis: after two groups of cases treat two courses for the treatment of, experimental group recovery from illness 101 example, take a turn for the better 51 examples, invalid 3 examples, total effective rate 98.06%; Matched group recovery from illness 36 example, take a turn for the better 82 examples, invalid 37 examples, total effective rate 76.13%.The cure rate of experimental group and total effective rate are apparently higher than matched group.The clinical efficacy of experimental group is obviously better than matched group, and significant difference (P < 0.05), has statistical significance.
The present invention is primary raw material medicine with Radix Cynanchi Paniculati, Citrus aurantium L. var. amara Engl., Herba Schizonepetae and Radix Clerodenri Cyrtophylli etc., makes the Chinese medicine preparation for the treatment of urticaria.Radix Cynanchi Paniculati analgesia in side, cough-relieving, inducing diuresis to remove edema, promoting blood circulation and detoxication.Citrus aurantium L. var. amara Engl. is regulated the flow of vital energy the chest stuffiness relieving, stomach function regulating preventing or arresting vomiting.Herba Schizonepetae is dispeled the wind, and induces sweat, rash, hemostasis.Radix Clerodenri Cyrtophylli heat clearing away, removing toxic substances, removing heat from blood.Chimonanthusn itens Oliv. expelling pathogenic wind from the body surface, removing dampness by means of aromatics.Lindera angustifolia Cheng dispels the wind, dehumidifying, circulation of qi promoting cold expelling, removing toxic substances and promoting subsidence of swelling.Rhizoma Polygonati Odorati nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid.Reboulia hemisphaerica heat-clearing and toxic substances removing, detumescence hemostasis.Herba Taraxaci heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.Radix seu Folium Alchorneae trewioidis clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, killing parasites for relieving itching.Caulis Hederae Sinensis is dispeled the wind, dampness removing, suppressing the hyperactive liver, removing toxic substances.Periostracum Cicadae has dispelling wind and heat pathogens, sore-throat relieving, rash, improving acuity of vision and removing nebula, effect of spasmolytic.Radix Stemonae nourishing the lung to arrest cough, parasite killing delousing.Radix clerodendri bungei circulation of qi promoting spleen invigorating, expelling wind and removing dampness, removing toxic substances and promoting subsidence of swelling, blood pressure lowering.Radix Clematidis wind-damp dispelling, the meridian dredging, expectorant saliva, the loose hypochondriac lump.Folium Eucalypti Robustae dispelling wind is delivered, expelling phlegm for arresting cough, heat-clearing and toxic substances removing, killing parasites for relieving itching.Herba Polygoni Orientalis root heat-clearing and toxic substances removing, eliminating dampness and dredging channels, promoting tissue regeneration and ulcer healing.Many medicines share, mutual coordination, there is the effect that expelling wind and cold, clearing away heat and cooling blood, circulation of qi promoting spleen invigorating, stomach function regulating preventing or arresting vomiting, nourishing YIN and moistening the lung, dispelling wind and heat pathogens, rash are antipruritic, autoimmunity can be strengthened, keep the dynamic equilibrium of body nature physiological property, recover skin oneself care action, treating both the principal and secondary aspects of a disease, not easily recurs.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. treat a Chinese medicine preparation for urticaria, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Cynanchi Paniculati 12-18, Citrus aurantium L. var. amara Engl. 10-16, Herba Schizonepetae 7-12, Radix Clerodenri Cyrtophylli 9-13, Chimonanthusn itens Oliv. 11-15, Lindera angustifolia Cheng 8-13, Rhizoma Polygonati Odorati 10-14, Reboulia hemisphaerica 7-11, Herba Taraxaci 10-15, Radix seu Folium Alchorneae trewioidis 9-12, Caulis Hederae Sinensis 11-14, Periostracum Cicadae 6-9, Radix Stemonae 8-11, Radix clerodendri bungei 9-14, Radix Clematidis 8-15, Folium Eucalypti Robustae 10-13, Herba Polygoni Orientalis root 12-16.
2. the Chinese medicine preparation for the treatment of urticaria as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Cynanchi Paniculati 14-17, Citrus aurantium L. var. amara Engl. 12-15, Herba Schizonepetae 8-11, Radix Clerodenri Cyrtophylli 10-12, Chimonanthusn itens Oliv. 12-14, Lindera angustifolia Cheng 9-11, Rhizoma Polygonati Odorati 11-13, Reboulia hemisphaerica 8-10, Herba Taraxaci 11-13, Radix seu Folium Alchorneae trewioidis 10-11, Caulis Hederae Sinensis 12-13, Periostracum Cicadae 7-8, Radix Stemonae 9-10, Radix clerodendri bungei 10-12, Radix Clematidis 9-12, Folium Eucalypti Robustae 11-12, Herba Polygoni Orientalis root 13-15.
3. the Chinese medicine preparation for the treatment of urticaria as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Cynanchi Paniculati 16, Citrus aurantium L. var. amara Engl. 14, Herba Schizonepetae 10, Radix Clerodenri Cyrtophylli 11, Chimonanthusn itens Oliv. 13, Lindera angustifolia Cheng 10, Rhizoma Polygonati Odorati 12, Reboulia hemisphaerica 9, Herba Taraxaci 12, Radix seu Folium Alchorneae trewioidis 10.5, Caulis Hederae Sinensis 12.5, Periostracum Cicadae 7.5, the Radix Stemonae 9.5, Radix clerodendri bungei 11, Radix Clematidis 10, Folium Eucalypti Robustae 11.5, Herba Polygoni Orientalis root 14.
4. the Chinese medicine preparation of the treatment urticaria as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine preparation of this treatment urticaria is made pharmaceutically acceptable decoction, and the preparation method of described decoction is:
(1) by Radix clerodendri bungei pulverization, cross No. four sieves, add water, amount of water is 9.6-14 times (preferred amount of water is 12.5 times of Radix clerodendri bungei weight) of Radix clerodendri bungei weight, 75 DEG C of stirring in water bath lixiviate 3-5 hour, with the centrifugation of 3200-3800r/min, centrifugalize 12-18 minute, gets supernatant for subsequent use;
(2) all the other the 13 taste crude drug except Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv., Radix clerodendri bungei and Folium Eucalypti Robustae are put into marmite, add water, amount of water is 4.9-6.7 times (preferred amount of water is 5.6 times of the 13 taste crude drug gross weights added) of the 13 taste crude drug gross weights added, soak 1 hour, first boil with high heat to boiling, after turn slow fire boiling 38-55 minute (preferably then turn slow fire boiling 46 minutes), leach medicinal liquid;
(3) Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv. and Folium Eucalypti Robustae are joined fill in the marmite of medicinal residues, add water, amount of water is 2.8-4.5 times (preferred amount of water is 3.5 times of all crude drug gross weights added) of all crude drug gross weights added, first boil with high heat to boiling, after turn slow fire boiling 28-40 minute (preferably then turn slow fire boiling 32 minutes), leach medicinal liquid;
(4) step (1), step (2) and step (3) gained medicinal liquid are mixed, to obtain final product.
5. the Chinese medicine preparation of the treatment urticaria as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine preparation of this treatment urticaria is made pharmaceutically acceptable powder, and the preparation method of described powder is:
(1) by Radix clerodendri bungei pulverization, cross No. four sieves, add water, amount of water is 9.6-14 times (preferred amount of water is 12.5 times of Radix clerodendri bungei weight) of Radix clerodendri bungei weight, 75 DEG C of stirring in water bath lixiviates 3-5 hour (preferably 75 DEG C stirring in water bath lixiviate 4 hours), with the centrifugation of 3200-3800r/min (preferably with the centrifugation of 3500r/min), centrifugalize 12-18 minute (preferred centrifugalize 15 minutes), gets supernatant for subsequent use;
(2) all the other the 13 taste crude drug except Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv., Radix clerodendri bungei and Folium Eucalypti Robustae are put into marmite, add water, amount of water is 4.9-6.7 times (preferred amount of water is 5.6 times of the 13 taste crude drug gross weights added) of the 13 taste crude drug gross weights added, soak 1 hour, first boil with high heat to boiling, after turn slow fire boiling 38-55 minute (preferably then turn slow fire boiling 46 minutes), leach medicinal liquid;
(3) Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv. and Folium Eucalypti Robustae are joined fill in the marmite of medicinal residues, add water, amount of water is 2.8-4.5 times (preferred amount of water is 3.5 times of all crude drug gross weights added) of all crude drug gross weights added, first boil with high heat to boiling, after turn slow fire boiling 28-40 minute (preferably then turn slow fire boiling 32 minutes), leach medicinal liquid;
(4) step (1), step (2) and step (3) gained medicinal liquid are mixed, concentrating under reduced pressure become relative density be 1.35 thick paste, 50 DEG C of dryings 12 hours, are ground into fine powder, cross No. eight sieves, often to wrap 4g subpackage, sterile packaged and get final product.
6. the Chinese medicine preparation of the treatment urticaria as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine preparation of this treatment urticaria is made pharmaceutically acceptable granule, and the preparation method of described granule is:
(1) by Radix clerodendri bungei pulverization, cross No. four sieves, add water, amount of water is 9.6-14 times (preferred amount of water is 12.5 times of Radix clerodendri bungei weight) of Radix clerodendri bungei weight, 75 DEG C of stirring in water bath lixiviates 3-5 hour (preferably 75 DEG C stirring in water bath lixiviate 4 hours), with the centrifugation of 3200-3800r/min (preferably with the centrifugation of 3500r/min), centrifugalize 12-18 minute (preferred centrifugalize 15 minutes), gets supernatant for subsequent use;
(2) all the other the 13 taste crude drug except Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv., Radix clerodendri bungei and Folium Eucalypti Robustae are put into marmite, add water, amount of water is 4.9-6.7 times (preferred amount of water is 5.6 times of the 13 taste crude drug gross weights added) of the 13 taste crude drug gross weights added, soak 1 hour, first boil with high heat to boiling, after turn slow fire boiling 38-55 minute (preferably then turn slow fire boiling 46 minutes), leach medicinal liquid;
(3) Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv. and Folium Eucalypti Robustae are joined fill in the marmite of medicinal residues, add water, amount of water is 2.8-4.5 times (preferred amount of water is 3.5 times of all crude drug gross weights added) of all crude drug gross weights added, first boil with high heat to boiling, after turn slow fire boiling 28-40 minute (preferably then turn slow fire boiling 32 minutes), leach medicinal liquid;
(4) step (1), step (2) and step (3) gained medicinal liquid are mixed, concentrating under reduced pressure become relative density be 1.35 thick paste, add sucrose, the weight of sucrose is the weight of the 1/3-3/5(preferably sucrose of gained thick paste gross weight is 1/2 of gained thick paste gross weight), mixing, make granule, 55 DEG C of dryings 10 hours, to obtain final product.
7. the Chinese medicine preparation of the treatment urticaria as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine preparation of this treatment urticaria is made pharmaceutically acceptable tablet, and the preparation method of described tablet is:
(1) by Radix clerodendri bungei pulverization, cross No. four sieves, add water, amount of water is 9.6-14 times (preferred amount of water is 12.5 times of Radix clerodendri bungei weight) of Radix clerodendri bungei weight, 75 DEG C of stirring in water bath lixiviates 3-5 hour (preferably 75 DEG C stirring in water bath lixiviate 4 hours), with the centrifugation of 3200-3800r/min (preferably with the centrifugation of 3500r/min), centrifugalize 12-18 minute (preferred centrifugalize 15 minutes), gets supernatant for subsequent use;
(2) all the other the 13 taste crude drug except Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv., Radix clerodendri bungei and Folium Eucalypti Robustae are put into marmite, add water, amount of water is 4.9-6.7 times (preferred amount of water is 5.6 times of the 13 taste crude drug gross weights added) of the 13 taste crude drug gross weights added, soak 1 hour, first boil with high heat to boiling, after turn slow fire boiling 38-55 minute (preferably then turn slow fire boiling 46 minutes), leach medicinal liquid;
(3) Citrus aurantium L. var. amara Engl., Chimonanthusn itens Oliv. and Folium Eucalypti Robustae are joined fill in the marmite of medicinal residues, add water, amount of water is 2.8-4.5 times (preferred amount of water is 3.5 times of all crude drug gross weights added) of all crude drug gross weights added, first boil with high heat to boiling, after turn slow fire boiling 28-40 minute (preferably then turn slow fire boiling 32 minutes), leach medicinal liquid;
(4) step (1), step (2) and step (3) gained medicinal liquid are mixed, concentrating under reduced pressure become relative density be 1.35 thick paste, add sucrose, the weight of sucrose is the weight of the 1/3-3/5(preferably sucrose of gained thick paste gross weight is 1/2 of gained thick paste gross weight), mixing, makes granule, 55 DEG C of dryings 10 hours, tabletting, the heavy 0.5g of every sheet, to obtain final product.
8. the preparation method of the Chinese medicine preparation decoction for the treatment of urticaria as claimed in claim 4, is characterized in that, 75 DEG C of stirring in water bath lixiviates 4 hours in step (1).
9. the preparation method of the Chinese medicine preparation decoction for the treatment of urticaria as claimed in claim 4, is characterized in that, with the centrifugation of 3500r/min in step (1).
10. the preparation method of the Chinese medicine preparation decoction for the treatment of urticaria as claimed in claim 4, is characterized in that, centrifugalize 15 minutes in step (1).
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101757588A (en) * | 2008-12-09 | 2010-06-30 | 景午辰 | Traditional Chinese medicine preparation for treating urticaria |
| CN102018811A (en) * | 2009-09-09 | 2011-04-20 | 马黎晓 | Chinese materia medica preparation for treating urticaria |
| CN104353000A (en) * | 2014-09-18 | 2015-02-18 | 董小红 | Traditional Chinese medicine pills for treating urticaria |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101757588A (en) * | 2008-12-09 | 2010-06-30 | 景午辰 | Traditional Chinese medicine preparation for treating urticaria |
| CN102018811A (en) * | 2009-09-09 | 2011-04-20 | 马黎晓 | Chinese materia medica preparation for treating urticaria |
| CN104353000A (en) * | 2014-09-18 | 2015-02-18 | 董小红 | Traditional Chinese medicine pills for treating urticaria |
Non-Patent Citations (3)
| Title |
|---|
| 张晓辉等: "中药口服配合拔火罐治疗慢性荨麻疹32例疗效观察", 《新中医》 * |
| 朱海莲: "中医辨证治疗荨麻疹的临床研究", 《中国优秀硕士学位论文全文数据库医药卫生科技辑》 * |
| 肖国士等: "《中医秘方全书》", 30 March 2012, 湖南科学技术出版社 * |
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