CN104906032A - 药物组合物 - Google Patents

药物组合物 Download PDF

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Publication number
CN104906032A
CN104906032A CN201510212609.XA CN201510212609A CN104906032A CN 104906032 A CN104906032 A CN 104906032A CN 201510212609 A CN201510212609 A CN 201510212609A CN 104906032 A CN104906032 A CN 104906032A
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CN
China
Prior art keywords
compositions
carbetocin
composition
buffer
agent
Prior art date
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Pending
Application number
CN201510212609.XA
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English (en)
Chinese (zh)
Inventor
安德斯·尼尔森
马蒂亚斯·马尔姆
卡齐米日·维希涅夫斯基
布里塔·西克曼
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Ferring BV
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Ferring BV
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43478408&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN104906032(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ferring BV filed Critical Ferring BV
Publication of CN104906032A publication Critical patent/CN104906032A/zh
Pending legal-status Critical Current

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    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
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    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/095Oxytocins; Vasopressins; Related peptides
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    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
CN201510212609.XA 2010-09-30 2011-09-29 药物组合物 Pending CN104906032A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10251690.3 2010-09-30
EP10251690 2010-09-30
CN2011800464547A CN103124554A (zh) 2010-09-30 2011-09-29 药物组合物

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN2011800464547A Division CN103124554A (zh) 2010-09-30 2011-09-29 药物组合物

Publications (1)

Publication Number Publication Date
CN104906032A true CN104906032A (zh) 2015-09-16

Family

ID=43478408

Family Applications (4)

Application Number Title Priority Date Filing Date
CN201510212609.XA Pending CN104906032A (zh) 2010-09-30 2011-09-29 药物组合物
CN2011800464547A Pending CN103124554A (zh) 2010-09-30 2011-09-29 药物组合物
CN201610930541.3A Pending CN107412728A (zh) 2010-09-30 2011-09-29 药物组合物
CN201610930206.3A Active CN107080832B (zh) 2010-09-30 2011-09-29 药物组合物

Family Applications After (3)

Application Number Title Priority Date Filing Date
CN2011800464547A Pending CN103124554A (zh) 2010-09-30 2011-09-29 药物组合物
CN201610930541.3A Pending CN107412728A (zh) 2010-09-30 2011-09-29 药物组合物
CN201610930206.3A Active CN107080832B (zh) 2010-09-30 2011-09-29 药物组合物

Country Status (27)

Country Link
US (4) US9566311B2 (enExample)
EP (5) EP3246018B1 (enExample)
JP (2) JP6038797B2 (enExample)
KR (2) KR101919119B1 (enExample)
CN (4) CN104906032A (enExample)
AU (1) AU2011309762B2 (enExample)
BR (2) BR112013007362B1 (enExample)
CA (1) CA2812510A1 (enExample)
CY (2) CY1119245T1 (enExample)
DK (4) DK3246018T3 (enExample)
ES (4) ES2902418T3 (enExample)
FI (1) FI4374878T3 (enExample)
HR (3) HRP20250382T1 (enExample)
HU (4) HUE070972T2 (enExample)
IL (3) IL225238B (enExample)
JO (3) JO3400B1 (enExample)
LT (3) LT4374878T (enExample)
MX (3) MX395271B (enExample)
NZ (1) NZ609719A (enExample)
PL (4) PL3222272T3 (enExample)
PT (4) PT3222272T (enExample)
RS (3) RS56220B1 (enExample)
RU (2) RU2604690C2 (enExample)
SI (4) SI4374878T1 (enExample)
SM (3) SMT202200034T1 (enExample)
TW (6) TWI650134B (enExample)
WO (1) WO2012042371A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110308222A (zh) * 2019-07-17 2019-10-08 武汉赛沃医药科技有限公司 一种卡贝缩宫素原料药有关物质检测方法
CN110997697A (zh) * 2017-08-11 2020-04-10 辉凌公司 制备药物组合物的方法

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070224184A1 (en) * 2006-02-22 2007-09-27 The Research Foundation Of The State University Of New York Method for treating cellulite
AU2013260209A1 (en) * 2012-05-08 2014-11-20 Dilafor Ab Treatment of postpartum haemorrhage with chemically modified heparin or heparan sulphate and a uterotonic agent
CN106714819A (zh) * 2014-09-19 2017-05-24 辉凌公司 治疗普拉德‑威利综合征的方法
EP3200773B1 (en) 2014-10-01 2018-07-18 Oxytone Bioscience B.V. Orally disintegrating solid pharmaceutical dosage unit containing a partus control substance
WO2016053091A1 (en) 2014-10-01 2016-04-07 Oxytone Bioscience B.V. Orally disintegrating solid pharmaceutical dosage unit containing a partus control substance
HRP20231438T1 (hr) 2015-01-07 2024-06-07 Tonix Pharma Limited Formulacije oksitocina koje sadrže magnezij i načini uporabe
WO2016162819A1 (en) * 2015-04-07 2016-10-13 Lupin Limited Stable aqueous pharmaceutical composition of anti-tnf alpha antibody
CN115814055A (zh) 2016-04-12 2023-03-21 三叉神经股份公司 含镁催产素制剂和应用方法
CN107773531B (zh) * 2016-08-31 2021-05-04 成都倍特药业股份有限公司 一种马来酸麦角新碱注射液
CN108236601B (zh) * 2016-12-23 2020-04-17 深圳翰宇药业股份有限公司 一种稳定的含卡贝缩宫素的阴道给药的药用组合物及其制备方法
GB201721846D0 (en) * 2017-12-22 2018-02-07 Arecor Ltd Novel composition
US11970554B2 (en) 2018-03-01 2024-04-30 Tonix Pharmaceuticals Holding Corp. Labeled oxytocin and method of manufacture and use
CN108721598B (zh) * 2018-07-03 2020-06-05 北京市新里程医药科技有限公司 一种缩宫素原料的制备方法及其药物组合物和制剂
JP7538802B2 (ja) 2018-09-20 2024-08-22 アカディア ファーマシューティカルズ インコーポレイテッド カルベトシン医薬品およびその製造プロセス
AU2019345166B2 (en) * 2018-09-20 2021-09-02 Levo Therapeutics, Inc. Stable intranasal formulations of carbetocin
CN109745544B (zh) * 2018-11-23 2024-11-08 南京新百药业有限公司 稳定的缩宫素药物组合物及其制备方法
EP3897571A1 (en) * 2018-12-21 2021-10-27 Arecor Limited Novel composition
JP7390031B2 (ja) * 2018-12-27 2023-12-01 国立大学法人金沢大学 オキシトシン誘導体及びその使用
CN114096267B (zh) 2019-05-22 2025-03-18 柏欧韦股份有限公司 特利加压素制剂
CN110403904A (zh) * 2019-07-26 2019-11-05 翔宇药业股份有限公司 卡贝缩宫素注射液及其应用
CN110237230A (zh) * 2019-07-31 2019-09-17 南京康舟医药科技有限公司 一种卡贝缩宫素药物组合物及其制备方法
EP4054521A1 (en) 2019-11-04 2022-09-14 Ferring B.V. Intranasal administration of merotocin for improving lactation
CN111012739A (zh) * 2019-12-04 2020-04-17 长春圣金诺生物制药有限公司 一种可以常温储存的含卡贝缩宫素及稳定剂的注射液
HRP20250303T1 (hr) 2021-03-26 2025-05-09 Centre Hospitalier Universitaire De Toulouse Liječenje disfagije
CN114191388B (zh) * 2021-12-27 2023-06-09 苏州天马医药集团天吉生物制药有限公司 一种卡贝缩宫素制剂的制备方法
CN114712483B (zh) * 2022-05-12 2023-09-29 成都倍特药业股份有限公司 一种麦角新碱缩宫素复方注射液及其制备方法和用途
US12214010B2 (en) 2023-04-04 2025-02-04 Tulex Pharmaceuticals Inc. Desmopressin oral compositions

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1109558A (zh) * 1994-11-07 1995-10-04 马文亮 装有压力表的双管气筒
CN1126440A (zh) * 1993-06-29 1996-07-10 凡林有限公司 稳定的药用肽组合物
WO2008042452A1 (en) * 2006-09-29 2008-04-10 Nastech Pharmaceutical Company Inc. Pharmaceutical compositions comprising oxytocin or an analog for the treatment of autism
WO2008150305A1 (en) * 2007-06-07 2008-12-11 Nastech Pharmaceutical Company Inc. Intranasal carbetocin formulations and methods for the treatment of autism
WO2009122285A1 (en) * 2008-03-31 2009-10-08 Ferring B.V. Oxitocin analogues

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9604341D0 (sv) * 1996-11-26 1996-11-26 Ferring Bv Hepta-peptide oxytocin analogue
EP1285667B1 (en) 1997-11-18 2006-06-14 Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. Pharmaceutical injectable solution of paracetamol and combinations of paracetamol with other active substances
US6333313B1 (en) 1998-10-29 2001-12-25 Board Of Regents, The University Of Texas System Clinical use of oxytocin alone or in combination to treat bone disorders
US6894026B1 (en) * 2000-01-11 2005-05-17 Atossa Healthcare, Inc. Long-acting oxytocin analogues for the treatment and prevention of breast cancer and psychiatric disorders
JP2001233787A (ja) * 2000-02-04 2001-08-28 Patents Exploitation Co Bv 小・中サイズのペプチド含有薬学的組成物
AT409081B (de) 2000-02-16 2002-05-27 Gebro Pharma Gmbh Stabile, nasal, oral oder sublingual anwendbare pharmazeutische zubereitung
EP1441589B1 (en) 2001-11-08 2012-05-09 Abbott Biotherapeutics Corp. Stable liquid pharmaceutical formulation of igg antibodies
EP1556068B1 (en) 2002-10-03 2010-08-18 Neuropharmacology Services, LLC Oxytocin for use in the treatment of Autism and Asperger's disorder
EA008038B1 (ru) 2003-01-08 2007-02-27 Чирон Корпорейшн Стабилизированные водные композиции, содержащие ингибитор пути метаболизма, тканевого фактора (tfpi) или вариант ингибитора пути метаболизма тканевого фактора
CN1938040A (zh) 2003-03-05 2007-03-28 Pr药品有限公司 缩宫素控释制剂及其应用方法
GT200600031A (es) * 2005-01-28 2006-08-29 Formulacion anticuerpo anti a beta
PL2178386T3 (pl) 2007-07-02 2011-04-29 Sime Darby Malaysia Berhad Kompozycja tłuszczu do smażenia
ES2319054B1 (es) 2007-08-06 2010-02-12 Gp Pharm S.A. Composicion farmaceutica oral de desmopresina.
US20100092566A1 (en) * 2008-10-15 2010-04-15 Alessi Thomas R Highly concentrated drug particles, formulations, suspensions and uses thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1126440A (zh) * 1993-06-29 1996-07-10 凡林有限公司 稳定的药用肽组合物
CN1109558C (zh) * 1993-06-29 2003-05-28 凡林有限公司 稳定的药用肽组合物
CN1109558A (zh) * 1994-11-07 1995-10-04 马文亮 装有压力表的双管气筒
WO2008042452A1 (en) * 2006-09-29 2008-04-10 Nastech Pharmaceutical Company Inc. Pharmaceutical compositions comprising oxytocin or an analog for the treatment of autism
WO2008150305A1 (en) * 2007-06-07 2008-12-11 Nastech Pharmaceutical Company Inc. Intranasal carbetocin formulations and methods for the treatment of autism
WO2009122285A1 (en) * 2008-03-31 2009-10-08 Ferring B.V. Oxitocin analogues

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110997697A (zh) * 2017-08-11 2020-04-10 辉凌公司 制备药物组合物的方法
CN110308222A (zh) * 2019-07-17 2019-10-08 武汉赛沃医药科技有限公司 一种卡贝缩宫素原料药有关物质检测方法

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