CN104888148B - A kind of drug for treating chronic hepatitis B - Google Patents

Abstract

The invention discloses a kind of drug for treating chronic hepatitis B, which includes radix bupleuri, Radix Paeoniae Alba, Radix Curcumae, Radix Angelicae Sinensis, fries the Chinese medicines such as fructus toosendan, Radix cynanchi wilfordii, the fruit-rind of Chinese trichosanthes, semen trichosanthis, safflower, hawthorn, green peel, pyrrosia lingua, aloe, the root of straight ladybell, madder, black nightshade, lobelia chinensis, Sculellaria barbata, oldenlandia diffusa, malt, Divine Comedy.The effective component specific aim of drug of the present invention acts on liver, and hepatotoxin is discharged by stool, urine, mitigates burden of liver, conducive to liver recovery, good to the therapeutic effect of hepatitis B, curative effect is fast, slight, moderate can be eradicated and severe hepatitis B patient, cure rate reach 96%.

Description

A kind of drug for treating chronic hepatitis B

Technical field

The present invention relates to a kind of drug, in particular to a kind of drug for treating chronic hepatitis B.

Background technique

Chronic hepatitis B（Abbreviation hepatitis B）Refer to hepatitis B test positive, the course of disease be more than half a year or date of the onset not It is clear and clinic has chronic hepatitis shower.It is divided into slight, moderate and severe according to clinical manifestation.Clinical manifestation is out of strength, fear The symptoms such as food, nausea, abdominal distension, hepatalgia, hepatomegaly, quality is medium hardness, there is light tenderness.State of an illness severe one can be with Chronic Liver Sick face, spider angioma, liver palms, splenomegaly, liver function can exception or persistent anomaly, cause primary carcinoma of liver.Show according to relevant information Since the route of transmission of hepatitis B is extensive, crowd's cross-infection rate is high, and the patient of China's hepatitis B tests positive has reached 1.8 hundred million, it is one of the infectious disease for currently endangering health of people most serious.Since most Western medicine are through liver detoxification, controlled using Western medicine Hepatitis B burden of liver easy to increase is treated, is unfavorable for treating hepatopathy.It is each that the effective component of Chinese medicine is distributed in whole body after patient absorbs Place, causes the drug effect concentration at liver too low, can not be treated for hepatitis B, poor to the therapeutic effect of hepatitis B, curative effect compared with Slowly.

Summary of the invention

The present invention provides a kind of drug for treating chronic hepatitis B, and the effective component specific aim of the drug acts on liver It is dirty, hepatotoxin is discharged by stool, urine, mitigates burden of liver, is conducive to liver and restores, curative effect good to the therapeutic effect of hepatitis B Fastly, slight, moderate can be eradicated and severe hepatitis B patient, cure rate reach 96%.

The first scheme of the invention is：A kind of drug for treating chronic hepatitis B, the parts by weight of the drug each component For：15-25 parts of radix bupleuri；15-30 parts of Radix Paeoniae Alba；15-30 parts of Radix Curcumae；10-25 parts of Radix Angelicae Sinensis；15-30 parts of stir-baked FRUCTUS TOOSENDAN；Radix cynanchi wilfordii 10- 25 parts；5-10 parts of the fruit-rind of Chinese trichosanthes；10-15 parts of semen trichosanthis；5-10 parts of safflower；15-30 parts of hawthorn；15-25 parts of green peel；Pyrrosia lingua 15-30 Part；5-15 parts of aloe；15-30 parts of the root of straight ladybell；15-20 parts of madder；15-20 parts of black nightshade；15-50 parts of lobelia chinensis；Sculellaria barbata 15-50 Part；15-50 parts of oldenlandia diffusa；10-30 parts of malt；15-30 parts of Divine Comedy；15-25 parts of polygonum cuspidate；10-20 parts of gentianae macrophyllae；RHIZOMA FAGOPYRI CYMOSI 15-30 parts；20-30 parts of hypericum japonicum.

Preferably, the parts by weight of said medicine each component are：20 parts of radix bupleuri；20 parts of Radix Paeoniae Alba；20 parts of Radix Curcumae；15 parts of Radix Angelicae Sinensis； 20 parts of stir-baked FRUCTUS TOOSENDAN；15 parts of Radix cynanchi wilfordii；5 parts of the fruit-rind of Chinese trichosanthes；15 parts of semen trichosanthis；5 parts of safflower；20 parts of hawthorn；20 parts of green peel；Pyrrosia lingua 20 parts；6 parts of aloe；20 parts of the root of straight ladybell；20 parts of madder；15 parts of black nightshade；30 parts of Sculellaria barbata；30 parts of lobelia chinensis；30 parts of oldenlandia diffusa； 20 parts of malt；20 parts of Divine Comedy；20 parts of polygonum cuspidate；15 parts of gentianae macrophyllae；20 parts of RHIZOMA FAGOPYRI CYMOSI；30 parts of hypericum japonicum.

Second scheme of the invention is：A kind of drug for treating chronic hepatitis B, the parts by weight of the drug each component For：15-25 parts of radix bupleuri；15-30 parts of Radix Paeoniae Alba；15-30 parts of Radix Curcumae；10-25 parts of Radix Angelicae Sinensis；15-30 parts of stir-baked FRUCTUS TOOSENDAN；Radix cynanchi wilfordii 10- 25 parts；5-10 parts of the fruit-rind of Chinese trichosanthes；10-15 parts of semen trichosanthis；5-10 parts of safflower；15-30 parts of hawthorn；15-25 parts of green peel；Pyrrosia lingua 15-30 Part；5-15 parts of aloe；15-30 parts of the root of straight ladybell；15-20 parts of madder；15-20 parts of black nightshade；15-50 parts of lobelia chinensis；Sculellaria barbata 15-50 Part；15-50 parts of oldenlandia diffusa；10-30 parts of malt；15-30 parts of Divine Comedy；15-20 parts of rhizome of cyrtomium；5-10 parts of pangolin；Turtle shell 15- 20 parts；25-30 parts of Radix Astragali.

Preferably, the parts by weight of said medicine each component are：25 parts of radix bupleuri；30 parts of Radix Paeoniae Alba；30 parts of Radix Curcumae；25 parts of Radix Angelicae Sinensis； 30 parts of stir-baked FRUCTUS TOOSENDAN；Prize 25 parts in lattice mountain；10 parts of the fruit-rind of Chinese trichosanthes；15 parts of semen trichosanthis；10 parts of safflower；30 parts of hawthorn；25 parts of green peel；Stone 30 parts of Wei；15 parts of aloe；30 parts of the root of straight ladybell；20 parts of madder；20 parts of black nightshade；50 parts of lobelia chinensis；50 parts of Sculellaria barbata；Oldenlandia diffusa 50 Part；30 parts of malt；30 parts of Divine Comedy；20 parts of rhizome of cyrtomium；10 parts of pangolin；20 parts of turtle shell；30 parts of Radix Astragali.

The third scheme of the invention is：A kind of drug for treating chronic hepatitis B, the parts by weight of the drug each component For：15-25 parts of radix bupleuri；15-30 parts of Radix Paeoniae Alba；15-30 parts of Radix Curcumae；10-25 parts of Radix Angelicae Sinensis；15-30 parts of stir-baked FRUCTUS TOOSENDAN；Prize 10- in lattice mountain 25 parts；5-10 parts of the fruit-rind of Chinese trichosanthes；10-15 parts of semen trichosanthis；5-10 parts of safflower；15-30 parts of hawthorn；15-25 parts of green peel；Pyrrosia lingua 15-30 Part；5-15 parts of aloe；15-30 parts of the root of straight ladybell；15-20 parts of madder；15-20 parts of black nightshade；15-50 parts of lobelia chinensis；Sculellaria barbata 15-50 Part；15-50 parts of oldenlandia diffusa；10-30 parts of malt；15-30 parts of Divine Comedy；5-15 parts of first pearl；15-30 parts of turtle shell；Radix Astragali 25-30 Part.

Preferably, the parts by weight of said medicine each component are：25 parts of radix bupleuri；30 parts of Radix Paeoniae Alba；30 parts of Radix Curcumae；25 parts of Radix Angelicae Sinensis； 30 parts of stir-baked FRUCTUS TOOSENDAN；Prize 25 parts in lattice mountain；10 parts of the fruit-rind of Chinese trichosanthes；15 parts of semen trichosanthis；10 parts of safflower；30 parts of hawthorn；25 parts of green peel；Stone 30 parts of Wei；15 parts of aloe；30 parts of the root of straight ladybell；20 parts of madder；20 parts of black nightshade；50 parts of lobelia chinensis；50 parts of Sculellaria barbata；Oldenlandia diffusa 50 Part；30 parts of malt；30 parts of Divine Comedy；10 parts of first pearl；30 parts of turtle shell；30 parts of Radix Astragali.

Drug of the present invention, 7 days as one therapeutic course, three times, each 10-15 grams, patient below 12 one full year of life is every for medication daily Secondary medication dose is 5-8 grams.

Drug each component of the present invention：

Radix bupleuri is smoked to alias, mountain dish, mushroom grass, faggot, bitter in taste, slightly cold, returns liver, gallbladder channel.Have in inducing diaphoresis, soothing the liver liter The effect of positive.For cold, fever, fevers and chills alternate, malaria, liver depression and qi stagnation, chest and rib distending pain, rectal prolapse, uterine prolapse, irregular menstruation.

White peony, also referred to as white flower Chinese herbaceous peony are Ranunculaceae Chinese herbaceous peony platymisciums.Radix Paeoniae Alba is cool in nature, bitter acid, slightly cold, has and enriches blood Blood-nourishing, suppressing liver-YANG, the analgesic of soft liver, astringing YIN to stop sweating and other effects, are suitable for fever due to yin deficiency, irregular menstruation, chest and abdomen pain over the hypochondriac region, four Limb contraction is anxious, diarrhea dysentery abdominal pain, spontaneous sweating, metrorrhagia and metrostaxis, with inferior disease.Modern medicine finds Radix Paeoniae Alba, and there are also protection livers to treat chronic The illnesss such as type hepatitis, cirrhosis.

Radix Curcumae is the dried root of zingiberaceous plant RADIX CURCUMAE, turmeric, Guangxi zedoary or zedoary.This product it is oval or Strip thin slice.Exocuticle lark, taupe to taupe brown, have irregular vertical wrinkle.It is section taupe brown, orange-yellow to grey Black.Cutin sample, endodermis ring are obvious.For pricking pain in the chest, chest impediment and cardialgia, amenorrhea and algomenorrhea, swollen breasts, pyreticosis coma is insane Epilepsy is gone mad, blood-head tells nosebleed, jaundice and reddish urine.

Radix Angelicae Sinensis, alias is dry to return, the Qin which, western Radix Angelicae Sinensis, Min Radix Angelicae Sinensis, Radix Angelicae Sinensis, when angelica body, contain that angelica tail, Radix Angelicae Sinensis be bent, araliae cordatae, It is one of most common Chinese medicine.With benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizing dryness and lubricating intestine, anticancer, anti-ageing the effect of preventing always, is immune.

Stir-baked FRUCTUS TOOSENDAN, arbor, bark taupe, sprig lark.Easypro liver promoting the circulation of qi, relieves pain expelling parasite, removes damp and hot, clearing away the liver-fire, Analgesic, desinsection.

Radix cynanchi wilfordii, alias radix cynanchi bungei, white grandmother, long bean clam, mountain excessively are floatd, without beam rattan.It is used as medicine with root tuber.It tonifies the liver and kidney, It strengthens muscles and bones.For neurasthenia, impotence, spermatorrhea, lumbocrural pain.

The fruit-rind of Chinese trichosanthes is the pericarp of cucurbitaceous plant snakegourd or trichosanthes rosthornii Harms etc..Moistening lung for removing phlegm, the sharp wide chest of gas.Control phlegm heat-syndrome cough It coughs, pharyngalgia, pectoralgia is spitted blood, and bleeding from five sense organs or subcutaneous tissue is quenched one's thirst, constipation, ulcerative carbuncle pyogenic infections.

Semen trichosanthis is the benevolence of the ripening fruits of cucurbitaceous plant snakegourd and trichosanthes rosthornii Harms.Clearing heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, ease constipation Defaecation.There is expansion heart coronary artery, increases coronary flow effect；There is significant protective effect to acute myocardial ischemia；To in vitro suede Cancer cell multiplication and AIDS virus have strong inhibiting effect；There is certain therapeutic effect to diabetes；To hypertension, high blood Rouge, high cholesterol have auxiliary curative effect；Body's immunity can be improved.

Safflower is the dry flower of compositae plant safflower.With blood circulation, the effect of removing blood stasis and acesodyne.For menostasis, pain Through, lochia, abdominal mass lump in the abdomen, chest impediment and cardialgia, stasis of blood, pricking pain in the chest, injury from falling down, sore swell and ache curative.

Hawthorn is the dry mature fruit of rosaceous plant large-fruited Chinese hawthorn or hawthorn.Food digesting stomach fortifying, scattered stasis change turbid drop Rouge.For meat stagnation, gastral cavilty turgor, diarrhea dysentery abdominal pain, blood stasis closed, postpartum stasis, confidant sting, chest impediment and cardialgia, hernia pain Bitterly, hyperlipidemia.

Green peel is the drying young fruit of rutaceae orange and its variety or the pericarp of immature fruit.Have soothing the liver broken Gas, the stagnant effect of disperse accumulationization.For distending pain in the chest and hypochondrium, hernia pain, breast illness, acute mastitis, stagnation of QI due to dyspepsia, abdominal distention.

Pyrrosia lingua is the dried leaf of Plants of Polypodiaceae pyrrosia sheareriChing, pyrrosia lingua or pyrrosia petiolosaChing.There is inducing diuresis for treating strangurtia, clearing lung-heat stops The effect of cough, cooling blood and hemostasis.For heat gonorrhea, blood strangury, urolithiasis, urinary obstruction, the puckery pain of leaching drip, dyspnea and cough due to lung-heat, haematemesis, bleeding from five sense organs or subcutaneous tissue, urine Blood, metrorrhagia and metrostaxis.

Aloe, Aloe are Liliaceae perennial evergreen herbaceous plant, purging intense heat；Removing toxic substances；Stagnation resolvation；Desinsection.Argument is red；Just It is secret；Gonorrhoea；Hematuria；Pediatric epilepsy scared；Infantile malnutrition due to digestive disturbances or intestinalparasites；Burn and scald；Women's amenorrhoea；Hemorrhoid；Scabies；Carbuncle and furuncle and pyogenic infections；Traumatic injury.Sterilization is made With anti-inflammatory effect moistens beautification function, the effect of letting out under stomach invigorating, and heart tonifying promoting blood circulation acts on, immune and palingenesis, is immunized and swells with anti- Tumor effect, detoxication, anti-aging effects, analgesia, sedation, anti-sunlight function.

The root of straight ladybell is《Chinese book on Chinese herbal medicine》The herbal medicine included, medicinal source be the root of straight ladybell be Campanulaceae the root of straight ladybell, apricot leaf the root of straight ladybell, Adenophora tetraphylla, Yunnan the root of straight ladybell steep the root of straight ladybell and its belong to the root of several plants.Alias：Adenophora tetraphylla, bubble ginseng, bubble the root of straight ladybell.The root of straight ladybell taste It is sweet；Slight bitter；Cold nature；Return lung；Stomach meridian.There is the effect of clearing heat and nourishing yin, moistening lung to arrest cough.Cure mainly tracheitis, pertussis, lung heat cough It coughs, cough up phlegm yellow thick.

Madder, Bie Ming Qian grass, acalyphae,herba, penang pronephrium herb, blood circulation promoting pill, Salvia kiaometiensis, it is red in disappear.Cooling and activating blood, dissolving stasis are led to Through.For spitting blood, bleeding from five sense organs or subcutaneous tissue, metrostaxis, traumatic hemorrhage, menostasis stasis blocking, arthralgia, tumbling and swelling.Cooling blood and hemostasis, promoting blood circulation are dispelled The stasis of blood.For heat symptom-complex bleeding, menostasis abdominal pain, traumatic injury.

Black nightshade, annual herb plant, herb are 30-120 centimetres high；Stem is upright, multi-branched；Oval or cardioid leaf is mutual It is raw, nearly full edge；Summer opens white little Hua, and 4-10 at cyme；Spherical berry is black purple after mature.Berry and leaf It is edible, but leaf contains a large amount of alkaloids, must can detoxify after cooked.Complete stool is used as medicine, can eliminating stasis to subdue swelling, heat-clearing solution Poison.

Sculellaria barbata is the drying herb of Lamiaceae plant Sculellaria barbata.It is clearing heat and detoxicating, stagnation resolvation diuresis.For furuncle swelling toxin, pharynx Larynx swelling and pain, the pain of injury caused by falling and tumbling, oedema, jaundice, snakebite and bugbite.

Lobelia chinensis belongs to Campanulaceae lobelia, You Mingwei：Anxious solution rope, thin spartina, half of flower, narcissus flowers and plants, the young grass of sickle Deng, all herbal medicine has inducing diuresis to remove edema, and it is clearing heat and detoxicating and other effects, extensive abdominal edema, face foot edema, carbuncle swells furunculosis, snakeworm can be treated It bites.

Oldenlandia diffusa is the herb of Rubiaceae plants of Hedyotis oldenlandia diffusa.Clearing heat and detoxicating, dampness removing is treating stranguria.For Dyspnea and cough due to lung-heat, abscess of throat, acute appendicitis, furuncle sore, venomous snake bite, puckery pain of heat gonorrhea, oedema, dysentery, enteritis, jaundice with damp-heat pathogen, cancer It is swollen.

Malt is the ripening fruits of the gramineae plant barley Preparation process product dry through germination.Promoting the circulation of qi helps digestion, invigorating the spleen are opened Stomach, delaactation dissipate-swelling.For dyspepsia, abdominal distention, spleen eating less, milk smoulders, swollen breasts, weaning women, the liver depression side of body Bitterly, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach.

Song made of flour or wheat bran post-fermentation is added for polygonum flaccidum, sweet wormwood, almond mud, rde bean, the fresh achene of Siberian cocklebur in Divine Comedy Agent.Strengthening the spleen and stomach, promoting digestion and removing indigestion.For retention of food and drink, indigestion, abdominal fullness and distention, loss of appetite, vomiting dysentery.

Polygonum cuspidate is the dry rhizome and root of polygonaceae plant polygonum cuspidate.It is clearing heat and detoxicating with removing dampness through diuresis and removing jaundice, removing blood stasis and acesodyne, cough-relieving The effect of resolving sputum.For jaundice with damp-heat pathogen, stranguria with turbid discharge, leukorrhagia, rheumatic arthralgia, carbuncle sore tumefacting virus, scald, menostasis, abdominal mass, instep beats damage Wound, cough with lung heat.

Gentianae macrophyllae is the dry root of gentianaceae plant gentianae macrophyllae, gentiana straminea maxim, gentiana crassicaulis Duthie or gentianae macrophyllae.There is wind-damp dispelling, it is clear wet Heat, stopping numbness pain, the effect of reducing the asthenic fever.For rheumatic arthralgia, apoplexy and hemiplegia, muscle arteries and veins contraction, skeletal pain, jaundice with damp-heat pathogen, Osteopyrexia and fever, infantile malnutrition generates heat.

RHIZOMA FAGOPYRI CYMOSI also known as RHIZOMA FAGOPYRI CYMOSI, Jinsuoyinkai ', cymose buckwheat rhizome are the rhizomes of plant polygonaceae tartary buckwheat.Have anti-inflammatory anti-swollen Tumor bacteriostasis.

The effect of hypericum japonicum is the herb of Garcinia maingayii hypericum japonicum, there is clearing heat and promoting diuresis, is detoxified, eliminating stasis to subdue swelling.For wet Hot jaundice, diarrhea, dysentery, acute appendicitis, carbuncle and furuncle and pyogenic infections, acute tonsillitis, aphtha, red eye, swell pain, venomous snake bite, traumatic injury.

Rhizome of cyrtomium is the rhizome and petiole residue of Dryopteridaceae plant dryopteris crassirhizoma.Desinsection；Heat-clearing；Removing toxic substances；Cool blood is stopped Blood.For anemopyretic cold；Warm ecchymosis；It spits blood；Hemoptysis；Bleeding from five sense organs or subcutaneous tissue；Hematochezia；Metrorrhagia and metrostaxis；Bloody flux；The intestines such as leukorrhagia and hook, ascarid, tapeworm are posted Infested disease.

Pangolin is the scale and shell of Manidae animal pangolin.Newborn under promoting menstruation with promoting blood circulation eliminating mass, it is logical to search wind for detumescence and apocenosis The effect of network.It is used for the mass amenorrhea due to blood stasis dredging, alactation, carbuncle sore tumefacting virus, rheumatic arthralgia, paralysis due to windstroke, numbness contracture.

Turtle shell is the carapace of cyprinidae.With nourishing and suppressing Yang, bring down a fever except steaming, the effect of resolving hard lump.It is usually used in yin It shoots without hitting the target heat, hectic fever due to yin labor heat, hyperactivity of yang due to yin deficiency is had a dizzy spell, endogenous deficient wind, menostasis , Disorder lump in the abdomen, chronic malaria malaria with abdominal mass.

Radix Astragali, also known as continuous stilbene.It has enhancing body's immunity, liver protection, diuresis, anti-aging, resisting stress, decompression and relatively extensively General antibacterial action.

First pearl is a kind of Chinese medicine, and there are also the names such as big gun first pearl, stir-baked SQUAMA MANITIS.Generally by pangolin（Pangolin）Scale and shell process after make With.Its taste is salty, cold nature, return liver warp, stomach meridian.Cream, anti-stain in solid under energy blood circulation promoting and dispersing pathogen accumulation, promoting menstruation.Main blood stasis, abdominal mass, wind Arthritis with fixed pain caused by dampness pain, agalactia, carbuncle swells, scrofula etc..

Drug component of the present invention is all made of commercially available Chinese medicine.

The component of drug of the present invention is traditional Chinese medicine, and use is safe, and cost of material is cheap, reduces hepatitis B trouble The treatment cost of person.By the synergistic effect of different component Chinese medicine, antipyretic, removing toxic substances, toxin expelling, particular for killing B-type hepatitis Poison has significant therapeutic effect to slight, moderate and severe hepatopath, is effectively improved, repairs function of liver and spleen.Therapeutic process is without pair Effect, the recurrence after healing can be avoided, while there are also benefiting actions to patient's constitution.

Pill administration is made in drug of the present invention for treating hepatitis B, decocts into aqua compared to traditional Chinese medicine and takes With, overcome traditional Chinese medicine and decoct into low, time-consuming, the laborious defect of the easy qualitative change of aqua, drug effect utilization rate, have carry, clothes With convenient, efficient advantage.

Parts by weight of the present invention be gram or kilogram.

Specific embodiment

Embodiment 1

Weigh Chinese medicine：20 grams of radix bupleuri；20 grams of Radix Paeoniae Alba；20 grams of Radix Curcumae；15 grams of Radix Angelicae Sinensis；20 grams of stir-baked FRUCTUS TOOSENDAN；Radix cynanchi wilfordii 15 Gram；5 grams of the fruit-rind of Chinese trichosanthes；15 grams of semen trichosanthis；5 grams of safflower；20 grams of hawthorn；20 grams of green peel；20 grams of pyrrosia lingua；6 grams of aloe；20 grams of the root of straight ladybell； 20 grams of madder；15 grams of black nightshade；30 grams of Sculellaria barbata；30 grams of lobelia chinensis；30 grams of oldenlandia diffusa；20 grams of malt；20 grams of Divine Comedy；Polygonum cuspidate 20 grams；15 grams of gentianae macrophyllae；20 grams of RHIZOMA FAGOPYRI CYMOSI；30 grams of hypericum japonicum.Each component is tentatively pulverized with herb roller respectively, then will be ground Each component after broken uses 10 mesh sieves respectively, with 10 mesh sieves, mistake after not pulverized again by the drug component of 10 meshes Each component after sieve mixes, milling to 0.8mm diameter particle, and in pellet processing machine plus water 4% mixes pelletization, wraps after drying, cooling Dress obtains the drug of the treatment chronic hepatitis B.

The each medication dose of obtained pill is 10-15 grams, and patient per's medication dose below 12 one full year of life is 5-8 grams, It is taken after mixing it with water with warm water, three times, 7 days as a course for the treatment of, can be needed to increase and decrease the course for the treatment of according to the state of an illness for medication daily.

Embodiment 2

Weigh Chinese medicine：25 grams of radix bupleuri；25 grams of Radix Paeoniae Alba；25 grams of Radix Curcumae；20 grams of Radix Angelicae Sinensis；25 grams of stir-baked FRUCTUS TOOSENDAN；Radix cynanchi wilfordii 20 Gram；10 grams of the fruit-rind of Chinese trichosanthes；15 grams of semen trichosanthis；8 grams of safflower；25 grams of hawthorn；20 grams of green peel；25 grams of pyrrosia lingua；10 grams of aloe；The root of straight ladybell 30 Gram；20 grams of madder；15 grams of black nightshade；30 grams of Sculellaria barbata；30 grams of lobelia chinensis；30 grams of oldenlandia diffusa；25 grams of malt；25 grams of Divine Comedy； 25 grams of polygonum cuspidate；15 grams of gentianae macrophyllae；30 grams of RHIZOMA FAGOPYRI CYMOSI；30 grams of hypericum japonicum.Each component is tentatively pulverized with herb roller respectively, then Each component after pulverizing is used into 10 mesh sieves respectively, with 10 mesh mistakes after not pulverizing again by the drug component of 10 meshes Sieve, each component after sieving mix, milling to 0.8mm diameter particle, and in pellet processing machine plus water 4% mixes pelletization, drying, cooling After pack, obtain it is described treatment chronic hepatitis B drug.

The each medication dose of obtained pill is 10-15 grams, and patient per's medication dose below 12 one full year of life is 5-8 grams, It is taken after mixing it with water with warm water, three times, 7 days as a course for the treatment of, can be needed to increase and decrease the course for the treatment of according to the state of an illness for medication daily.

Embodiment 3

Weigh Chinese medicine：25 grams of radix bupleuri；30 grams of Radix Paeoniae Alba；30 grams of Radix Curcumae；25 grams of Radix Angelicae Sinensis；30 grams of stir-baked FRUCTUS TOOSENDAN；Lattice mountain sled 25 Gram；10 grams of the fruit-rind of Chinese trichosanthes；15 grams of semen trichosanthis；10 grams of safflower；30 grams of hawthorn；25 grams of green peel；30 grams of pyrrosia lingua；15 grams of aloe；The root of straight ladybell 30 Gram；20 grams of madder；20 grams of black nightshade；50 grams of lobelia chinensis；50 grams of Sculellaria barbata；50 grams of oldenlandia diffusa；30 grams of malt；30 grams of Divine Comedy； 20 grams of rhizome of cyrtomium；10 grams of pangolin；20 grams of turtle shell；30 grams of Radix Astragali.Each component is tentatively pulverized with herb roller respectively, then will Each component after pulverizing uses 10 mesh sieves respectively, with 10 mesh sieves after not pulverized again by the drug components of 10 meshes, Each component after sieving mixes, milling to 0.8mm diameter particle, and in pellet processing machine plus water 4% mixes pelletization, wraps after drying, cooling Dress obtains the drug of the treatment chronic hepatitis B.

The each medication dose of obtained pill is 10-15 grams, and patient per's medication dose below 12 one full year of life is 5-8 grams, It is taken after mixing it with water with warm water, three times, 7 days as a course for the treatment of, can be needed to increase and decrease the course for the treatment of according to the state of an illness for medication daily.

Embodiment 4

Weigh Chinese medicine：25 grams of radix bupleuri；30 grams of Radix Paeoniae Alba；30 grams of Radix Curcumae；25 grams of Radix Angelicae Sinensis；30 grams of stir-baked FRUCTUS TOOSENDAN；Lattice mountain sled 25 Gram；10 grams of the fruit-rind of Chinese trichosanthes；15 grams of semen trichosanthis；10 grams of safflower；30 grams of hawthorn；25 grams of green peel；30 grams of pyrrosia lingua；15 grams of aloe；The root of straight ladybell 30 Gram；20 grams of madder；20 grams of black nightshade；50 grams of lobelia chinensis；50 grams of Sculellaria barbata；50 grams of oldenlandia diffusa；30 grams of malt；30 grams of Divine Comedy； 10 grams of first pearl；30 grams of turtle shell；30 grams of Radix Astragali.Each component is tentatively pulverized with herb roller respectively, it is each after then pulverizing Component uses 10 mesh sieves respectively, each after sieving with 10 mesh sieves after not pulverized again by the drug component of 10 meshes Component mixes, milling to 0.8mm diameter particle, and in pellet processing machine plus water 4% mixes pelletization, packs after drying, cooling, obtains institute State the drug for the treatment of chronic hepatitis B.

The each medication dose of obtained pill is 10-15 grams, and patient per's medication dose below 12 one full year of life is 5-8 grams, It is taken after mixing it with water with warm water, three times, 7 days as a course for the treatment of, can be needed to increase and decrease the course for the treatment of according to the state of an illness for medication daily.

Clinical practice：

1. certain is male, 65 years old, suffer from hepatitis B 15 years.In April, 2015, unexpected hepatalgia, chest is swollen, is severe second through hospital diagnosis Liver causes Primary hepatic carcinoma cell to spread.Leave hospital after taking 1 course for the treatment of of pill described in embodiment 4, pill 12 described in following the service of going home A course for the treatment of, stable disease, liver cancer cells are effectively controlled, and check through hospital, and liver cancer cells are without transfer.

2. certain is male, 36 years old, in August, 2012 checked to be positive for three indices(HBsAg, HBeAg, HBcAb) of hepatitis B, hepatosplenomegaly, mid-term liver cancer through hospital, belonged to severe Hepatitis B.Patient's do not feel like eating, general power is drowsiness, yellowish fur.3 courses for the treatment of of pill described in embodiment 4 are taken, hepatosplenomegaly is eliminated, 6 courses for the treatment of of following the service, positive for three indices(HBsAg, HBeAg, HBcAb) of hepatitis B symptom disappear, check through hospital, and patient's body liver cancer cells disappear, and patient gets well, Return visit in 2 years is not recurred.

3. certain female, 22 years old, 19 years old when, checks hepatitis B "small three positive", while general power is drowsiness, belongs to slight hepatitis B.Take embodiment 19 courses for the treatment of of the pill check that the recovery from illness of hepatitis B "small three positive", return visit in 2 years are not recurred through hospital.

4. certain female, 12 years old, in November, 2004 thought that liver does not relax, and breathes hard is not thought to eat, oil smoke vomiting is heard, hepatic region has Secret anguish is positive for three indices(HBsAg, HBeAg, HBcAb) of hepatitis B through hospital diagnosis, belongs to moderate hepatitis B.Dull pain in liver disappears after taking 3 courses for the treatment of of pill described in embodiment 2 It removes, continues to fully recover after taking 8 courses for the treatment of through hospital's inspection positive for three indices(HBsAg, HBeAg, HBcAb) of hepatitis B, return visit in 2 years is not recurred.

5. certain female 47 years old, checks to be positive for three indices(HBsAg, HBeAg, HBcAb) of hepatitis B through hospital, patient shows breathes hard, and anorexia is lean and haggard, Belong to moderate hepatitis B.5 courses for the treatment of of pill described in embodiment 4 are taken, patient restores the preferable state of mind, and appetite is normal, following the service 6 treatments Cheng Jing hospital checks that positive for three indices(HBsAg, HBeAg, HBcAb) of hepatitis B recovery from illness, return visit in 5 years are not recurred.

……

Applicant is by more than 490 example clinical practices, and using drug therapy of the present invention, slight, moderate, severe hepatitis B are suffered from Person, cure rate reach 96%, wherein light, moderate hepatitis B patient cures 210, and severe hepatitis B patient cures 262.

Claims (6)

1. a kind of drug for treating chronic hepatitis B, which is characterized in that the parts by weight of the drug each component are：

15-25 parts of radix bupleuri；15-30 parts of Radix Paeoniae Alba；15-30 parts of Radix Curcumae；

10-25 parts of Radix Angelicae Sinensis；15-30 parts of stir-baked FRUCTUS TOOSENDAN；10-25 parts of Radix cynanchi wilfordii；

5-10 parts of the fruit-rind of Chinese trichosanthes；10-15 parts of semen trichosanthis；5-10 parts of safflower；

15-30 parts of hawthorn；15-25 parts of green peel；15-30 parts of pyrrosia lingua；

5-15 parts of aloe；15-30 parts of the root of straight ladybell；15-20 parts of madder；

15-20 parts of black nightshade；15-50 parts of lobelia chinensis；15-50 parts of Sculellaria barbata；

15-50 parts of oldenlandia diffusa；10-30 parts of malt；15-30 parts of Divine Comedy；

15-25 parts of polygonum cuspidate；10-20 parts of gentianae macrophyllae；15-30 parts of RHIZOMA FAGOPYRI CYMOSI；

20-30 parts of hypericum japonicum.

2. drug according to claim 1, which is characterized in that the parts by weight of the drug each component are：

20 parts of radix bupleuri；20 parts of Radix Paeoniae Alba；20 parts of Radix Curcumae；

15 parts of Radix Angelicae Sinensis；20 parts of stir-baked FRUCTUS TOOSENDAN；15 parts of Radix cynanchi wilfordii；

5 parts of the fruit-rind of Chinese trichosanthes；15 parts of semen trichosanthis；5 parts of safflower；

20 parts of hawthorn；20 parts of green peel；20 parts of pyrrosia lingua；

6 parts of aloe；20 parts of the root of straight ladybell；20 parts of madder；

15 parts of black nightshade；30 parts of Sculellaria barbata；30 parts of lobelia chinensis；

30 parts of oldenlandia diffusa；20 parts of malt；20 parts of Divine Comedy；

20 parts of polygonum cuspidate；15 parts of gentianae macrophyllae；20 parts of RHIZOMA FAGOPYRI CYMOSI；

30 parts of hypericum japonicum.

3. a kind of drug for treating chronic hepatitis B, which is characterized in that the parts by weight of the drug each component are：

15-25 parts of radix bupleuri；15-30 parts of Radix Paeoniae Alba；15-30 parts of Radix Curcumae；

10-25 parts of Radix Angelicae Sinensis；15-30 parts of stir-baked FRUCTUS TOOSENDAN；10-25 parts of Radix cynanchi wilfordii；

5-10 parts of the fruit-rind of Chinese trichosanthes；10-15 parts of semen trichosanthis；5-10 parts of safflower；

15-30 parts of hawthorn；15-25 parts of green peel；15-30 parts of pyrrosia lingua；

5-15 parts of aloe；15-30 parts of the root of straight ladybell；15-20 parts of madder；

15-20 parts of black nightshade；15-50 parts of lobelia chinensis；15-50 parts of Sculellaria barbata；

15-50 parts of oldenlandia diffusa；10-30 parts of malt；15-30 parts of Divine Comedy；

15-20 parts of rhizome of cyrtomium；5-10 parts of pangolin；15-20 parts of turtle shell；

25-30 parts of Radix Astragali.

4. drug according to claim 3, which is characterized in that the parts by weight of the drug each component are：

25 parts of radix bupleuri；30 parts of Radix Paeoniae Alba；30 parts of Radix Curcumae；

25 parts of Radix Angelicae Sinensis；30 parts of stir-baked FRUCTUS TOOSENDAN；25 parts of Radix cynanchi wilfordii；

10 parts of the fruit-rind of Chinese trichosanthes；15 parts of semen trichosanthis；10 parts of safflower；

30 parts of hawthorn；25 parts of green peel；30 parts of pyrrosia lingua；

15 parts of aloe；30 parts of the root of straight ladybell；20 parts of madder；

20 parts of black nightshade；50 parts of lobelia chinensis；50 parts of Sculellaria barbata；

50 parts of oldenlandia diffusa；30 parts of malt；30 parts of Divine Comedy；

20 parts of rhizome of cyrtomium；10 parts of pangolin；20 parts of turtle shell；

30 parts of Radix Astragali.

5. a kind of drug for treating chronic hepatitis B, which is characterized in that the parts by weight of the drug each component are：

15-25 parts of radix bupleuri；15-30 parts of Radix Paeoniae Alba；15-30 parts of Radix Curcumae；

10-25 parts of Radix Angelicae Sinensis；15-30 parts of stir-baked FRUCTUS TOOSENDAN；10-25 parts of Radix cynanchi wilfordii；

5-10 parts of the fruit-rind of Chinese trichosanthes；10-15 parts of semen trichosanthis；5-10 parts of safflower；

15-30 parts of hawthorn；15-25 parts of green peel；15-30 parts of pyrrosia lingua；

5-15 parts of aloe；15-30 parts of the root of straight ladybell；15-20 parts of madder；

15-20 parts of black nightshade；15-50 parts of lobelia chinensis；15-50 parts of Sculellaria barbata；

15-50 parts of oldenlandia diffusa；10-30 parts of malt；15-30 parts of Divine Comedy；

5-15 parts of first pearl；15-30 parts of turtle shell；25-30 parts of Radix Astragali.

6. drug according to claim 5, which is characterized in that the parts by weight of the drug each component are：

25 parts of radix bupleuri；30 parts of Radix Paeoniae Alba；30 parts of Radix Curcumae；

25 parts of Radix Angelicae Sinensis；30 parts of stir-baked FRUCTUS TOOSENDAN；25 parts of Radix cynanchi wilfordii；

10 parts of the fruit-rind of Chinese trichosanthes；15 parts of semen trichosanthis；10 parts of safflower；

30 parts of hawthorn；25 parts of green peel；30 parts of pyrrosia lingua；

15 parts of aloe；30 parts of the root of straight ladybell；20 parts of madder；

20 parts of black nightshade；50 parts of lobelia chinensis；50 parts of Sculellaria barbata；

50 parts of oldenlandia diffusa；30 parts of malt；30 parts of Divine Comedy；

10 parts of first pearl；30 parts of turtle shell；30 parts of Radix Astragali.