CN104888061A - Traditional Chinese medicine medicament for treating gout and preparation method for traditional Chinese medicine medicament - Google Patents

Traditional Chinese medicine medicament for treating gout and preparation method for traditional Chinese medicine medicament Download PDF

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CN104888061A
CN104888061A CN201510381037.8A CN201510381037A CN104888061A CN 104888061 A CN104888061 A CN 104888061A CN 201510381037 A CN201510381037 A CN 201510381037A CN 104888061 A CN104888061 A CN 104888061A
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李军
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Abstract

The invention discloses a traditional Chinese medicine medicament for treating gout. The traditional Chinese medicine medicament is prepared from the following raw materials in parts by mass: 11-15 parts of cacumen biotae, 7-11 parts of fatsia japonica, 9-17 parts of rubus crataegifolius, 12-16 parts of scented daphne leaves, 8-17 parts of beautiful sweetgum fruits, 10-16 parts of orange jessamine roots, 8-13 parts of needle juniper, 9-19 parts of jasmines, 6-10 parts of chinaroot greenbrier, 6-12 parts of ligusticum, 9-13 parts of indian damnacanthus herb, 7-12 parts of bauhinia champloni, 5-12 parts of acacia wood skin, 10-14 parts of herba siegesbeckiae and 7-15 parts of rhaphidophora peepla. According to the summary on multi-year clinical practice, the traditional Chinese medicine medicament has the effects of dispelling the wind and easing pain, and relaxing tendons and activating collaterals, and is remarkable in curative effect.

Description

Chinese medicine for the treatment of gout and preparation method thereof
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to Chinese medicine for the treatment of gout and preparation method thereof.
Background technology
Gout is the crystal dependency arthrosis caused by monosodium urate salt (MSU) deposits, directly related with the hyperuricemia caused by purine metabolic disturbance and (or) underexcretion.Gout is more common in middle-aged male, and women only accounts for 5%, mainly postmenopausal women, and gout has rejuvenation trend.The natural history of gout can be divided into the fourth phase, i.e. asymptomatic hyperuricemia phase, acute stage, intermission, chronic phase.Clinical manifestation is: 1. acute gouty arthritis, without obvious sign before most of patients outbreak, or only has tired, general malaise and joint sting etc.Typical onset is often waken up with a start the late into the night because of arthralgia, and pain Progressive symmetric erythrokeratodermia aggravates, and reaches peak at 12 hours, and in tearing sample, lancinate sample or sting and bite sample, is difficult to stand.Affected joints and surrounding tissue is red, swollen, hot, pain and function limitation.More than spontaneous remission in a couple of days or 2 weeks.2. interval stage of attack, can spontaneous remission after gout outbreak last from days to several weeks, general without obvious sequela shape, or leave over localised skin pigmentation, desquamation and scratchy etc., enter the asymptomatic intermission later, recur after lasting several months, several years or more than ten years, most of patients recurred in 1 year, all the more more frequently, affected joints gets more and more, and duration of symptoms is more and more longer.3. the chronic gout stone pathological changes phase, subcutaneous tophus and chronic gout stone arthritis are long-term significant hyperuricemias, and a large amount of monosodium urate salt crystal deposition is in the result of subcutaneous, synovium of joint, cartilage, sclerotin and periarticular soft tissues.The typical parts that subcutaneous tophus occurs is auricle, is also common in the positions such as the periarticular of recurrent exerbation and olecranon, heel string and patella synovial bursa.4. nephropathy, urate crystals is deposited on renal interstitial, causes chronic renal tubule one interstitial nephritis; Urine uric acid concentration increases in hypersaturated state, deposits and form calculus in urinary system; Blood and the hurried rising of urine uric acid level, a large amount of uric acid crystal is deposited on the place such as renal tubules, collecting tubule, causes acute urinary tract obstruction.
Publication No. CN 104352901 A(application number 201410526496.6) Chinese patent literature to disclose a kind of take vegetable Chinese herbal medicine as the Chinese medicine of the treatment gout that raw material is made.The Chinese medicine for the treatment of gout of the present invention, comprises following component: the Radix Astragali, the Radix Paeoniae Alba, Semen Coicis, Semen Plantaginis, Rhizoma Et Radix Notopterygii, Rhizoma Arisaematis (processed) , Rhizoma Dioscoreae Septemlobae, Radix Angelicae Sinensis, Rhizoma Smilacis Glabrae, Radix Saposhnikoviae, Radix Clematidis, Cortex Cinnamomi, Nidus Vespae, Herba Lysimachiae.Publication No. CN 103705809 A(application number 201310751419.6) Chinese patent literature disclose a kind of Chinese medicine for the treatment of gout, it is made up of the material medicine proportioning of following weight: Rhizoma Smilacis Glabrae 20g , Rhizoma Dioscoreae Septemlobae 15g, Caulis Lonicerae 20g , Herba Siegesbeckiae 12g, Herba Plantaginis 20g, Rhizoma Alismatis 10g, Herba Lycopi 10g, Pheretima 10g, Herba Leonuri 10g, Talcum 10g, Rhizoma Chuanxiong 10g, Semen Coicis 20g, Radix Angelicae Sinensis 10g, Rhizoma Atractylodis 12g, Cortex Phellodendri 10g, Radix Achyranthis Bidentatae 12g, Cortex Fraxini 10g, Endothelium Corneum Gigeriae Galli 12g, Radix Clematidis 12g, Semen Persicae 10g, Rhizoma Atractylodis Macrocephalae 10g, succinum 3g, Radix Glycyrrhizae 6g.Publication No. CN 103735630 A(application number 201310723192.4) Chinese patent literature disclose a kind of Chinese medicine for the treatment of gout.The medical material of this Chinese medicine consists of Semen Plantaginis and Caulis Perillae, and the Chinese medicine for the treatment of gout provided by the invention is safe and effective, and production cost is low, and instructions of taking is simple, cheap, and energy long-term taking, has no side effect.
This disease of current western medical treatment, based on anti-inflammatory analgesic, is cured the symptoms, not the disease, and side effect is comparatively large, easily rebounds after drug withdrawal, for alleviating patient body burden, improving therapeutic effect, should develop a kind of evident in efficacy, safe Chinese medicine formula.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, the Chinese medicine taking the wide treatment gout of safe and applicable and preparation method thereof.
Technical scheme of the present invention is:
The Chinese medicine for the treatment of gout, is prepared from primarily of following bulk drugs, is mass parts: Cacumen Platycladi 11-15; Rhizoma et Radix Dysosmae Veitchii 7-11; Pallet 9-17; Folium daphnes odorae 12-16; Fructus Liquidambaris 8-17; Radix Murrayae 10-16; Juniperus rigida Sieb.et Zucc. 8-13; Fructus Gardeniae 9-19; Rhizoma Smilacis Chinensis 6-10; Rhizoma Ligustici 6-12; Herba Damnacanthi 9-13; Caulis Bauhiniae Championii 7-12; Fructus Gleditsia veneer 5-12; Herba Siegesbeckiae 10-14; great Ye south Soviet Union 7-15.
Preferred version is, Cacumen Platycladi 12-14; Rhizoma et Radix Dysosmae Veitchii 8-10; Pallet 11-15; Folium daphnes odorae 13-15; Fructus Liquidambaris 10-15; Radix Murrayae 11-15; Juniperus rigida Sieb.et Zucc. 9-12; Fructus Gardeniae 11-17; Rhizoma Smilacis Chinensis 7-9; Rhizoma Ligustici 8-10; Herba Damnacanthi 10-12; Caulis Bauhiniae Championii 9-10; Fructus Gleditsia veneer 7-10; Herba Siegesbeckiae 11-13; great Ye south Soviet Union 9-13.
More preferably, Cacumen Platycladi 13; Rhizoma et Radix Dysosmae Veitchii 9; Pallet 13; Folium daphnes odorae 14; Fructus Liquidambaris 12.5; Radix Murrayae 13; Juniperus rigida Sieb.et Zucc. 10.5; Fructus Gardeniae 14; Rhizoma Smilacis Chinensis 8; Rhizoma Ligustici 9; Herba Damnacanthi 11; Caulis Bauhiniae Championii 9.5; Fructus Gleditsia veneer 8.5; Herba Siegesbeckiae 12; great Ye south Soviet Union 11.
The Chinese medicine of described treatment gout, be made into pharmaceutically acceptable granule, its preparation method is:
(1) get Rhizoma et Radix Dysosmae Veitchii, Folium daphnes odorae and Fructus Gleditsia veneer removing impurity, be placed in pot, intense fire is heated to surperficial pitchy, Guan Huohou, Rhizoma Zingiberis Recens block is chopped into end, puts into pot, mix thoroughly, and airtight 8-16 minute (preferred: airtight 12 minutes), takes out, pulverize;
(2) get Fructus Liquidambaris and Juniperus rigida Sieb.et Zucc. to clean, be placed in steamer, moderate heat water proof heating 20-30 minute is (preferred: water proof heating 22-28 minute; Be more preferably: water proof heats 25 minutes), take out, be placed in hot pot together with coarse sand, it is yellow that intense fire is heated to medical material surface zoom, and take out, sieve removes coarse sand, smashs to pieces;
(3) Fructus Gardeniae is cleaned remove impurity, add rice vinegar and infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), taking-up is sprinkled into Sal and mixes thoroughly, is placed in parch container, and slow fire is fried to dry, takes out and pulverizes together with step (1) (2) made crude drug;
(4) Cacumen Platycladi, pallet, Radix Murrayae, Rhizoma Smilacis Chinensis, Rhizoma Ligustici, Herba Damnacanthi, Caulis Bauhiniae Championii, Herba Siegesbeckiae and large Ye Nansu remove impurity are cleaned, be placed in marmite, add boiled crude drug quality 6-9 water doubly (preferably: add boiled crude drug quality 7-8 water doubly; Be more preferably: the water adding boiled crude drug quality 7.5 times) decoct, big fire is heated to boiling, turns little fire and decocts, Guan Huohou, collecting by filtration filtrate;
(5) step (4) remaining filtering residue is mixed with step (3) gained medicated powder, add water and again decoct 25 minutes, merge twice gained filtrate, concentrate drying, add adjuvant and pulverize, make graininess, obtain granule.
The preparation method of the Chinese medicine granule of described treatment gout, step (4) turns little fire and decocts 28-46 minute (preferably: turn little fire and decoct 32-42 minute; Be more preferably: turn little fire and decoct 37 minutes).
The Chinese medicine of described treatment gout, be made into pharmaceutically acceptable unguentum, its preparation method is:
(1) get Rhizoma et Radix Dysosmae Veitchii, Folium daphnes odorae and Fructus Gleditsia veneer removing impurity, be placed in pot, intense fire is heated to surperficial pitchy, Guan Huohou, Rhizoma Zingiberis Recens block is chopped into end, puts into pot, mix thoroughly, and airtight 8-16 minute (preferred: airtight 12 minutes), takes out, pulverize;
(2) get Fructus Liquidambaris and Juniperus rigida Sieb.et Zucc. to clean, be placed in steamer, moderate heat water proof heating 20-30 minute is (preferred: water proof heating 22-28 minute; Be more preferably: water proof heats 25 minutes), take out, be placed in hot pot together with coarse sand, it is yellow that intense fire is heated to medical material surface zoom, and take out, sieve removes coarse sand, smashs to pieces;
(3) Fructus Gardeniae is cleaned remove impurity, add rice vinegar and infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), taking-up is sprinkled into Sal and mixes thoroughly, is placed in parch container, and slow fire is fried to dry, takes out and pulverizes together with step (1) (2) made crude drug;
(4) Cacumen Platycladi, pallet, Radix Murrayae, Rhizoma Smilacis Chinensis, Rhizoma Ligustici, Herba Damnacanthi, Caulis Bauhiniae Championii, Herba Siegesbeckiae and large Ye Nansu remove impurity are cleaned, be placed in marmite, add boiled crude drug quality 6-9 water doubly (preferably: add boiled crude drug quality 7-8 water doubly; Be more preferably: the water adding boiled crude drug quality 7.5 times) decoct, big fire is heated to boiling, turns little fire decoction 28-46 minute (preferred: to turn little fire and decoct 32-42 minute; Be more preferably: turn little fire and decoct 37 minutes), Guan Huohou, collecting by filtration filtrate;
(5) by step (3) (4) gained medicated powder and filtrate mixing, heating is concentrated into thick paste, obtains unguentum.
The preparation method of the Chinese medicine unguentum of described treatment gout, it is (preferred: heating is concentrated into the thick paste that relative density is 1.14-1.20 that step (5) heating is concentrated into the thick paste (65 DEG C) that relative density is 1.10-1.24; Be more preferably: heating is concentrated into the thick paste that relative density is 1.17).
The Chinese medicine of described treatment gout, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get Rhizoma et Radix Dysosmae Veitchii, Folium daphnes odorae and Fructus Gleditsia veneer removing impurity, be placed in pot, intense fire is heated to surperficial pitchy, Guan Huohou, Rhizoma Zingiberis Recens block is chopped into end, puts into pot, mix thoroughly, and airtight 8-16 minute (preferred: airtight 12 minutes), takes out, pulverize;
(2) get Fructus Liquidambaris and Juniperus rigida Sieb.et Zucc. to clean, be placed in steamer, moderate heat water proof heating 20-30 minute is (preferred: water proof heating 22-28 minute; Be more preferably: water proof heats 25 minutes), take out, be placed in hot pot together with coarse sand, it is yellow that intense fire is heated to medical material surface zoom, and take out, sieve removes coarse sand, smashs to pieces;
(3) Fructus Gardeniae is cleaned remove impurity, add rice vinegar and infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), taking-up is sprinkled into Sal and mixes thoroughly, is placed in parch container, and slow fire is fried to dry, takes out and pulverizes together with step (1) (2) made crude drug;
(4) Cacumen Platycladi, pallet, Radix Murrayae, Rhizoma Smilacis Chinensis, Rhizoma Ligustici, Herba Damnacanthi, Caulis Bauhiniae Championii, Herba Siegesbeckiae and large Ye Nansu remove impurity are cleaned, be placed in marmite, add boiled crude drug quality 6-9 water doubly (preferably: add boiled crude drug quality 7-8 water doubly; Be more preferably: the water adding boiled crude drug quality 7.5 times) decoct, big fire is heated to boiling, turns little fire decoction 28-46 minute (preferred: to turn little fire and decoct 32-42 minute; Be more preferably: turn little fire and decoct 37 minutes), Guan Huohou, collecting by filtration filtrate;
(5) spray drying step (4) gained filtrate, mixes dry thing with step (3) made medicated powder, pulverizes and sieves, and adds water generally to make ball, obtains pill.
The preparation method of the Chinese medicine pill of described treatment gout, it is (preferred: to pulverize 80-100 mesh sieve that step (5) pulverized 60-120 mesh sieve; Be more preferably: pulverized 90 mesh sieves).
The Chinese medicine of described treatment gout, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Rhizoma et Radix Dysosmae Veitchii, Folium daphnes odorae and Fructus Gleditsia veneer removing impurity, be placed in pot, intense fire is heated to surperficial pitchy, Guan Huohou, Rhizoma Zingiberis Recens block is chopped into end, puts into pot, mix thoroughly, and airtight 8-16 minute (preferred: airtight 12 minutes), takes out, pulverize;
(2) get Fructus Liquidambaris and Juniperus rigida Sieb.et Zucc. to clean, be placed in steamer, moderate heat water proof heating 20-30 minute is (preferred: water proof heating 22-28 minute; Be more preferably: water proof heats 25 minutes), take out, be placed in hot pot together with coarse sand, it is yellow that intense fire is heated to medical material surface zoom, and take out, sieve removes coarse sand, smashs to pieces;
(3) Fructus Gardeniae is cleaned remove impurity, add rice vinegar and infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), taking-up is sprinkled into Sal and mixes thoroughly, is placed in parch container, and slow fire is fried to dry, takes out and pulverizes together with step (1) (2) made crude drug;
(4) Cacumen Platycladi, pallet, Radix Murrayae, Rhizoma Smilacis Chinensis, Rhizoma Ligustici, Herba Damnacanthi, Caulis Bauhiniae Championii, Herba Siegesbeckiae and large Ye Nansu remove impurity are cleaned, be placed in marmite, add boiled crude drug quality 6-9 water doubly (preferably: add boiled crude drug quality 7-8 water doubly; Be more preferably: the water adding boiled crude drug quality 7.5 times) decoct, big fire is heated to boiling, turns little fire decoction 28-46 minute (preferred: to turn little fire and decoct 32-42 minute; Be more preferably: turn little fire and decoct 37 minutes), Guan Huohou, collecting by filtration filtrate;
(5) by step (3) (4) gained medicated powder and filtrate mixing, heating is concentrated, dries and pulverizes, obtain powder.
The preparation method of the Chinese medicine powder of described treatment gout, step (5) is dried and was pulverized 120-240 mesh sieve (preferably: pulverized 150-210 mesh sieve; Be more preferably: pulverized 180 mesh sieves).
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Cacumen Platycladi: nature and flavor with return through: bitter, puckery, cold.Return lung, liver, spleen channel.Function with cure mainly: cooling blood for hemostasis, preventing phlegm from forming and stopping coughing, growing and blacking hair.For spitting blood, epistaxis, spitting of blood, has blood in stool, metrostaxis, cough due to lung-heat, heat in blood alopecia, early whitening of beard and hair.
Rhizoma et Radix Dysosmae Veitchii: base is former: be leaf or the root bark of Araliaceae Rhizoma et Radix Dysosmae Veitchii.Nature and flavor: acrid in the mouth; Bitter; Warm in nature; Mild toxicity.Function cures mainly: preventing phlegm from forming and stopping coughing; Loose wind dehumidifying; Blood-activating analgetic.Main cough with copious phlegm; Rheumatic arthralgia; Gout; Traumatic injury.
Pallet: base is former: be the root of Rosaceae rubus pallet.The property of medicine: acid, micro-hardship, flat.Function cures mainly: heat-clearing and toxic substances removing, reducing swelling and alleviating pain, hemostasis.Cure mainly influenza, children with high fever induced convulsions, laryngopharynx swelling and pain, toothache, headache, bones and muscles pain due to rheumatism, furuncle and phyma.
Folium daphnes odorae: base is former: be the branch and leaf of Isolated From Thymelaeaceae Species winter daphne.Nature and flavor: acrid in the mouth; Property is put down.Gui Jing: lung; Spleen channel.Function cures mainly: removing toxic substances; Reducing swelling and alleviating pain.Main skin infection; Acute mastitis; Gout.
Fructus Liquidambaris: base is former: be the infructescence of Hamamelidaceae Plants Chinese sweet gum.Nature and flavor: bitter; Flat.Gui Jing: return liver, kidney channel.Function cures mainly: expelling wind and removing dampness; Soothing the liver active; Diuretic.Main air pain of dampness syndrome; Numb limbs and tense tendons; Contracture of the limbs; Epigastric pain; Amenorrhea; Galactostasis; Edema distension; Eczema.
Radix Murrayae: base is former: be the root of rutaceae Folium Et Cacumen Murrayae.Nature and flavor: " mountain of papers Chinese herbal medicine ": " acrid in the mouth is bitter, warm in nature." return through: " Guangxi Chinese medicinal herbal ": " enters the heart, liver, lung three warp." function cures mainly: dispelling the wind and dampness pathogens arthralgia pain, lumbago, traumatic injury, painful and swollen testis, eczema, scabies.
Juniperus rigida Sieb.et Zucc.: base is former: be branch and leaf and the cone of Cupressaceae plant Juniperus rigida Sieb.et Zucc..Nature and flavor: sweet; Bitter; Property is put down.Function cures mainly: dispel the wind; Analgesia; Dehumidifying; Diuresis.Main rheumatic arthritis; Gout; Nephritis; Edema; Urinary tract infection.
Fructus Gardeniae: bitter in the mouth, cold in nature.Have pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, effect of removing pathogenic heat from blood and toxic substance from the body, vexed for calentura, heat in blood tells nosebleed, conjunctival congestion and swelling pain.
Rhizoma Smilacis Chinensis: base is former: be the rhizome of liliaceous plant Rhizoma Smilacis Chinensis.Nature and flavor: sweet; Acid; Property is put down.Gui Jing: liver; Kidney channel.Function cures mainly: expelling wind and removing dampness; Removing toxicity for eliminating carbuncles.Main air pain of dampness syndrome; Stranguria with turbid discharge; Leukorrhagia; Have loose bowels; Dysentery; Carbuncle sore tumefacting virus; Stubborn dermatitis; Burn and scald.
Rhizoma Ligustici: base is former: be rhizome and the root of samphire Rhizoma Ligustici or Rhizoma Ligustici, fiery Rhizoma Ligustici.Nature and flavor with return through: pungent, temperature.Return urinary bladder channel.Dispel the wind, cold expelling, dehumidifying, effect of pain relieving.For anemofrigid cold, top, mountain peak pain, rheumatic arthralgia.
Herba Damnacanthi: base is former: be herb or the root of Maguireothamnus speciosus Herba Damnacanthi.Nature and flavor: bitter sweet are flat.Function cures mainly: expelling wind and removing dampness, promoting blood circulation and detumescence.Control gout, rheumatic arthralgia.Cough due to fluid-retention, lung abscess, edema, mass in the abdomen, jaundice, women's amenorrhea, infantile malnutrition, urticaria, traumatic injury.
Caulis Bauhiniae Championii: base is former: be root or the leaf of menispermaceous plants ferrum rattan.Nature and flavor: bitter; Cold.Gui Jing: lung meridian.Function cures mainly: heat-clearing and toxic substances removing; Relieving stranguria by diuresis; Wind-expelling pain-stopping.Main laryngopharynx swelling and pain, diphtheria, pyretic stranguria, stranguria caused by urinary stone, toothache, stomachache, rheumatic arthralgia, carbuncle sore tumefacting virus, venom.
Fructus Gleditsia veneer: base is former: be used as medicine by the root bark of deciduous tree Fructus Gleditsia or peel of stem, autumn and winter gather, and section is dried.Nature and flavor with return through acrid in the mouth, warm in nature, nontoxic.There is the effect such as detoxicating and resolving stagnation of pathogens, wind dispelling insecticide.Cure mainly innominate toxic swelling, scabies, malignant boil, lymphoid tuberculosis, rheumatic ostalgia etc.
Herba Siegesbeckiae: base is former: be the aerial parts of feverfew Herba Siegesbeckiae.Chemical analysis: Han Herba Siegesbeckiae tetrol, still containing alkaloid, amaroid.Nature and flavor: cold in nature, acrid in the mouth, hardship.Function cures mainly: wind-damp dispelling, sharp joint, removing toxic substances., soreness of the waist and knees, quadriplegia, hemiplegia, rubella eczema unable for rheumatic arthralgia, muscles and bones.
Large Ye Nansu: base is former: be the Herb of the large Ye Nansu of aroid.Nature and flavor: bitter in the mouth; Micro-sweet; Cool in nature.Function cures mainly: eliminating stasis to stop pain; Relaxing muscles and tendons and activating QI and blood in the collateral; Nourishing the lung to arrest cough.Main angina pectoris; Treating swelling and pain by traumatic injury; Fracture; Rheumatalgia; Numb limbs and tense tendons; Bronchitis; Pertussis.
The Chinese medicine scientific formulation for the treatment of gout provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, therapeutic effect is good, and cure rate is high, effectively can prevent Relapse rate;
2, this formula is summed up through clinical practice for many years and is formed, and has effect of dispel the wind analgesia, relaxing muscles and tendons and activating QI and blood in the collateral;
3, Chinese crude drug selected by the present invention, safety has no side effect, and significantly can reduce patient body burden.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1the Chinese medicine for the treatment of gout, is prepared from (every part of 10g) primarily of following bulk drugs: Cacumen Platycladi 11 parts, Rhizoma et Radix Dysosmae Veitchii 7 parts, 9 parts, pallet, Folium daphnes odorae 12 parts, Fructus Liquidambaris 8 parts, Radix Murrayae 10 parts, Juniperus rigida Sieb.et Zucc. 8 parts, Fructus Gardeniae 9 parts, Rhizoma Smilacis Chinensis 6 parts, Rhizoma Ligustici 6 parts, Herba Damnacanthi 9 parts, Caulis Bauhiniae Championii 7 parts, Fructus Gleditsia veneer 5 parts, Herba Siegesbeckiae 10 parts, great Ye south Soviet Union 7 parts.The preparation method of the Chinese medicine granule of above-mentioned treatment gout is:
(1) get Rhizoma et Radix Dysosmae Veitchii, Folium daphnes odorae and Fructus Gleditsia veneer removing impurity, be placed in pot, intense fire is heated to surperficial pitchy, Guan Huohou, Rhizoma Zingiberis Recens block is chopped into end, puts into pot, mix thoroughly, airtight 12 minutes, takes out, pulverizes;
(2) get Fructus Liquidambaris and Juniperus rigida Sieb.et Zucc. to clean, be placed in steamer, moderate heat water proof heats 25 minutes, takes out, is placed in hot pot together with coarse sand, and it is yellow that intense fire is heated to medical material surface zoom, and take out, sieve removes coarse sand, smashs to pieces;
(3) Fructus Gardeniae is cleaned remove impurity, add rice vinegar and infiltrate 15 minutes, taking-up is sprinkled into Sal and mixes thoroughly, is placed in parch container, and slow fire is fried to dry, takes out and pulverizes together with step (1) (2) made crude drug;
(4) Cacumen Platycladi, pallet, Radix Murrayae, Rhizoma Smilacis Chinensis, Rhizoma Ligustici, Herba Damnacanthi, Caulis Bauhiniae Championii, Herba Siegesbeckiae and large Ye Nansu remove impurity are cleaned, be placed in marmite, add the soak by water of boiled crude drug quality 7.5 times, big fire is heated to boiling, turn little fire to decoct 37 minutes, Guan Huohou, collecting by filtration filtrate;
(5) step (4) remaining filtering residue is mixed with step (3) gained medicated powder, add water and again decoct 25 minutes, merge twice gained filtrate, concentrate drying, add adjuvant and pulverize, make graininess, obtain granule.
embodiment 2the Chinese medicine for the treatment of gout, is prepared from (every part of 10g) primarily of following bulk drugs: Cacumen Platycladi 15 parts, Rhizoma et Radix Dysosmae Veitchii 11 parts, 17 parts, pallet, Folium daphnes odorae 16 parts, Fructus Liquidambaris 17 parts, Radix Murrayae 16 parts, Juniperus rigida Sieb.et Zucc. 13 parts, Fructus Gardeniae 19 parts, Rhizoma Smilacis Chinensis 10 parts, Rhizoma Ligustici 12 parts, Herba Damnacanthi 13 parts, Caulis Bauhiniae Championii 12 parts, Fructus Gleditsia veneer 12 parts, Herba Siegesbeckiae 14 parts, great Ye south Soviet Union 15 parts.The preparation method of the Chinese medicine unguentum of above-mentioned treatment gout is:
(1) get Rhizoma et Radix Dysosmae Veitchii, Folium daphnes odorae and Fructus Gleditsia veneer removing impurity, be placed in pot, intense fire is heated to surperficial pitchy, Guan Huohou, Rhizoma Zingiberis Recens block is chopped into end, puts into pot, mix thoroughly, airtight 12 minutes, takes out, pulverizes;
(2) get Fructus Liquidambaris and Juniperus rigida Sieb.et Zucc. to clean, be placed in steamer, moderate heat water proof heats 25 minutes, takes out, is placed in hot pot together with coarse sand, and it is yellow that intense fire is heated to medical material surface zoom, and take out, sieve removes coarse sand, smashs to pieces;
(3) Fructus Gardeniae is cleaned remove impurity, add rice vinegar and infiltrate 15 minutes, taking-up is sprinkled into Sal and mixes thoroughly, is placed in parch container, and slow fire is fried to dry, takes out and pulverizes together with step (1) (2) made crude drug;
(4) Cacumen Platycladi, pallet, Radix Murrayae, Rhizoma Smilacis Chinensis, Rhizoma Ligustici, Herba Damnacanthi, Caulis Bauhiniae Championii, Herba Siegesbeckiae and large Ye Nansu remove impurity are cleaned, be placed in marmite, add the soak by water of boiled crude drug quality 7.5 times, big fire is heated to boiling, turn little fire to decoct 37 minutes, Guan Huohou, collecting by filtration filtrate;
(5) by step (3) (4) gained medicated powder and filtrate mixing, heating is concentrated into the thick paste (65 DEG C) that relative density is 1.17, obtains unguentum.
Model case: xxx, male, 48 years old.Medical history: without obvious inducement, patient occurred that foot joint swelled and ache before 3 years, night increases the weight of, and originally thinking overworks just does not take notice of, frequently drinks because of busy the adding that work afterwards, right hand articulations digitorum manus also starts to swell and ache, once took analgesic, the state of an illness is slightly alleviated, recent state of an illness aggravation, then examination in hospital is arrived, blood uric acid 802umol/L, the right hand points out existing tophus tuberosity, is diagnosed as gout.
Take this example gained unguentum, each 6-10g, warm boiled water, one day twice, within ten days, be a course for the treatment of, after patient takes a course for the treatment of, pain is obviously alleviated, after adhering to taking two courses for the treatment of, further consultation check, serum uric acid level drops to normally, after consolidate again one week, joint recovers normal, follows up a case by regular visits in half a year and does not recur.
embodiment 3the Chinese medicine for the treatment of gout, is prepared from (every part of 10g) primarily of following bulk drugs: Cacumen Platycladi 12 parts, Rhizoma et Radix Dysosmae Veitchii 8 parts, 11 parts, pallet, Folium daphnes odorae 13 parts, Fructus Liquidambaris 10 parts, Radix Murrayae 11 parts, Juniperus rigida Sieb.et Zucc. 9 parts, Fructus Gardeniae 11 parts, Rhizoma Smilacis Chinensis 7 parts, Rhizoma Ligustici 8 parts, Herba Damnacanthi 10 parts, Caulis Bauhiniae Championii 9 parts, Fructus Gleditsia veneer 7 parts, Herba Siegesbeckiae 11 parts, great Ye south Soviet Union 9 parts.The preparation method of the Chinese medicine pill of above-mentioned treatment gout is:
(1) get Rhizoma et Radix Dysosmae Veitchii, Folium daphnes odorae and Fructus Gleditsia veneer removing impurity, be placed in pot, intense fire is heated to surperficial pitchy, Guan Huohou, Rhizoma Zingiberis Recens block is chopped into end, puts into pot, mix thoroughly, airtight 12 minutes, takes out, pulverizes;
(2) get Fructus Liquidambaris and Juniperus rigida Sieb.et Zucc. to clean, be placed in steamer, moderate heat water proof heats 25 minutes, takes out, is placed in hot pot together with coarse sand, and it is yellow that intense fire is heated to medical material surface zoom, and take out, sieve removes coarse sand, smashs to pieces;
(3) Fructus Gardeniae is cleaned remove impurity, add rice vinegar and infiltrate 15 minutes, taking-up is sprinkled into Sal and mixes thoroughly, is placed in parch container, and slow fire is fried to dry, takes out and pulverizes together with step (1) (2) made crude drug;
(4) Cacumen Platycladi, pallet, Radix Murrayae, Rhizoma Smilacis Chinensis, Rhizoma Ligustici, Herba Damnacanthi, Caulis Bauhiniae Championii, Herba Siegesbeckiae and large Ye Nansu remove impurity are cleaned, be placed in marmite, add the soak by water of boiled crude drug quality 7.5 times, big fire is heated to boiling, turn little fire to decoct 37 minutes, Guan Huohou, collecting by filtration filtrate;
(5) spray drying step (4) gained filtrate, mixes dry thing with step (3) made medicated powder, pulverized 90 mesh sieves, adds water generally to make ball, obtains pill.
Model case: xxx, women, 31 years old.Main suit: left side toes arthralgia, cannot walk; Medical history: patient has a dinner party together with friend, after heavy drinking, cause suddenly toes joint, left side pain, cannot walk, the obvious congested swelling in joint, skin surface reddens, and has burning sensation, sends to examination in hospital, is diagnosed as gouty arthritis acute attack.
Recommend to take this example gained pill, each 3-4 grain, warm boiled water, one day twice through people, within ten days, be a course for the treatment of, after patient takes three days, uncomfortable disease obviously alleviates, after adhering to taking two courses for the treatment of, all diseases disappear entirely, and check indices all recovers normal, and follow up a case by regular visits in 1 year, the state of an illness is not repeatedly.
embodiment 4the Chinese medicine for the treatment of gout, is prepared from (every part of 10g) primarily of following bulk drugs: Cacumen Platycladi 14 parts, Rhizoma et Radix Dysosmae Veitchii 10 parts, 15 parts, pallet, Folium daphnes odorae 15 parts, Fructus Liquidambaris 15 parts, Radix Murrayae 15 parts, Juniperus rigida Sieb.et Zucc. 12 parts, Fructus Gardeniae 17 parts, Rhizoma Smilacis Chinensis 9 parts, Rhizoma Ligustici 10 parts, Herba Damnacanthi 12 parts, Caulis Bauhiniae Championii 10 parts, Fructus Gleditsia veneer 10 parts, Herba Siegesbeckiae 13 parts, great Ye south Soviet Union 13 parts.The preparation method of the Chinese medicine powder of above-mentioned treatment gout is:
(1) get Rhizoma et Radix Dysosmae Veitchii, Folium daphnes odorae and Fructus Gleditsia veneer removing impurity, be placed in pot, intense fire is heated to surperficial pitchy, Guan Huohou, Rhizoma Zingiberis Recens block is chopped into end, puts into pot, mix thoroughly, airtight 12 minutes, takes out, pulverizes;
(2) get Fructus Liquidambaris and Juniperus rigida Sieb.et Zucc. to clean, be placed in steamer, moderate heat water proof heats 25 minutes, takes out, is placed in hot pot together with coarse sand, and it is yellow that intense fire is heated to medical material surface zoom, and take out, sieve removes coarse sand, smashs to pieces;
(3) Fructus Gardeniae is cleaned remove impurity, add rice vinegar and infiltrate 15 minutes, taking-up is sprinkled into Sal and mixes thoroughly, is placed in parch container, and slow fire is fried to dry, takes out and pulverizes together with step (1) (2) made crude drug;
(4) Cacumen Platycladi, pallet, Radix Murrayae, Rhizoma Smilacis Chinensis, Rhizoma Ligustici, Herba Damnacanthi, Caulis Bauhiniae Championii, Herba Siegesbeckiae and large Ye Nansu remove impurity are cleaned, be placed in marmite, add the soak by water of boiled crude drug quality 7.5 times, big fire is heated to boiling, turn little fire to decoct 37 minutes, Guan Huohou, collecting by filtration filtrate;
(5) by step (3) (4) gained medicated powder and filtrate mixing, heating is concentrated, dries and pulverizes 180 mesh sieves, obtain powder.
Model case: xxx, male, 36 years old.Main suit: patient must have gout 2 years, trick arthralgia, cannot normal activity when being in a bad way; skin surface is tight rubescent; have sense of touching a tender spot, epidermis is without breakage, and duration of seizure increases gradually; bitter taste; yellow and greasy fur, wiry and frequent pulse, blood uric acid reaches as high as 934 umol/L; period once treated, and effect is all bad.
Learn take this example gained powder, each 3-4g, warm boiled water through asking about, one day twice ten days is a course for the treatment of, after patient takes a course for the treatment of, arthralgia is alleviated, can be slightly movable, after taking again a course for the treatment of, pain is eliminated substantially, can normally walk, uncomfortable disease is eliminated substantially, after consolidate again a course for the treatment of, patient fully recovers.
embodiment 5the Chinese medicine for the treatment of gout, is prepared from (every part of 10g) primarily of following bulk drugs: Cacumen Platycladi 13 parts, Rhizoma et Radix Dysosmae Veitchii 9 parts, 13 parts, pallet, Folium daphnes odorae 14 parts, Fructus Liquidambaris 12.5 parts, Radix Murrayae 13 parts, Juniperus rigida Sieb.et Zucc. 10.5 parts, Fructus Gardeniae 14 parts, Rhizoma Smilacis Chinensis 8 parts, Rhizoma Ligustici 9 parts, Herba Damnacanthi 11 parts, Caulis Bauhiniae Championii 9.5 parts, Fructus Gleditsia veneer 8.5 parts, Herba Siegesbeckiae 12 parts, great Ye south Soviet Union 11 parts.The preparation method of the Chinese medicine granule of above-mentioned treatment gout is:
(1) get Rhizoma et Radix Dysosmae Veitchii, Folium daphnes odorae and Fructus Gleditsia veneer removing impurity, be placed in pot, intense fire is heated to surperficial pitchy, Guan Huohou, Rhizoma Zingiberis Recens block is chopped into end, puts into pot, mix thoroughly, airtight 12 minutes, takes out, pulverizes;
(2) get Fructus Liquidambaris and Juniperus rigida Sieb.et Zucc. to clean, be placed in steamer, moderate heat water proof heats 25 minutes, takes out, is placed in hot pot together with coarse sand, and it is yellow that intense fire is heated to medical material surface zoom, and take out, sieve removes coarse sand, smashs to pieces;
(3) Fructus Gardeniae is cleaned remove impurity, add rice vinegar and infiltrate 15 minutes, taking-up is sprinkled into Sal and mixes thoroughly, is placed in parch container, and slow fire is fried to dry, takes out and pulverizes together with step (1) (2) made crude drug;
(4) Cacumen Platycladi, pallet, Radix Murrayae, Rhizoma Smilacis Chinensis, Rhizoma Ligustici, Herba Damnacanthi, Caulis Bauhiniae Championii, Herba Siegesbeckiae and large Ye Nansu remove impurity are cleaned, be placed in marmite, add the soak by water of boiled crude drug quality 7.5 times, big fire is heated to boiling, turn little fire to decoct 37 minutes, Guan Huohou, collecting by filtration filtrate;
(5) step (4) remaining filtering residue is mixed with step (3) gained medicated powder, add water and again decoct 25 minutes, merge twice gained filtrate, concentrate drying, add adjuvant and pulverize, make graininess, obtain granule.
test example 1the clinical practice of the Chinese medicine (embodiment 5) of gained treatment gout of the present invention:
Choose crowd: in January, 2014 in December ,-2014, according to medical case history, be patient 330 example of gout at six hospital's Screening Diagnosis, age 18-68 year, 40.6 ± 3.4 years old mean age, the course of disease 3 days-5 years, wherein male patient 206 example, female patient 124 example.Diagnostic criteria: 1., more than acute arthritis outbreak once, namely reached outbreak peak in 1 day; 2. acute arthritis is confined to indivedual joint; 3. whole joint is kermesinus; 4. the first toe joint swells and ache; 5. the scorching acute attack of one-sided toe joint; 6. there is tophus; 7. there is hyperuricemia; 8. asymmetry arthralgia; 9. outbreak can stop voluntarily, every possess this standard more than 3, and can except secondary gout person, can make a definite diagnosis.
Before test, patient is divided into two groups at random, experimental group 196 example and matched group 134 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes products obtained therefrom of the present invention, each 3-4g, one day twice, warm boiled water, within ten days, is a course for the treatment of; Matched group takes other conventional medicines (colchicines tablets, allopurinol tablet, TONGFENGDING capsule, wind pain spirit etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: clinical symptom disappearance, and each index checking of laboratory is normal; (2) take a turn for the better: arthroncus is disappeared, pain relief, and lab index inspection makes moderate progress; (3) invalid: clinical symptoms and lab testing unchanged.
Clinical effectiveness: after the taking medicine of two courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1:
As shown in Table 1, the healing patient of experimental group is 143 examples, and cure rate is 73.0%, improvement patient is 49 examples, and improvement rate is 25.0%, and total effective rate is 98.0%, and the patient that matched group is cured is 68 examples, cure rate is 50.7%, and the patient of improvement is 40 examples, and improvement rate is 29.9%, total effective rate 80.6%, significantly lower than the therapeutic effect of experimental group, illustrate that products obtained therefrom of the present invention is evident in efficacy, cure rate is high.
The Chinese medicine used in the present invention, Cacumen Platycladi cooling blood for hemostasis, Rhizoma et Radix Dysosmae Veitchii blood-activating analgetic, pallet, Folium daphnes odorae reducing swelling and alleviating pain, Fructus Liquidambaris, Herba Siegesbeckiae expelling wind and removing dampness, Radix Murrayae dispelling the wind and dampness pathogens arthralgia pain, Juniperus rigida Sieb.et Zucc. is dispeled the wind analgesia, Fructus Gardeniae removing pathogenic heat from blood and toxic substance from the body, Rhizoma Smilacis Chinensis removing toxicity for eliminating carbuncles, Rhizoma Ligustici removing damp and stopping pain, Herba Damnacanthi promoting blood circulation and detumescence, Caulis Bauhiniae Championii heat-clearing and toxic substances removing, Fructus Gleditsia veneer wind dispelling insecticide, large Ye Nansu relaxing muscles and tendons and activating QI and blood in the collateral, multiple medical material synergism, plays effect of removing damp and stopping pain, relaxing muscles and tendons and activating QI and blood in the collateral, promoting blood circulation and detoxication altogether.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. treat the Chinese medicine of gout, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Cacumen Platycladi 11-15; Rhizoma et Radix Dysosmae Veitchii 7-11; Pallet 9-17; Folium daphnes odorae 12-16; Fructus Liquidambaris 8-17; Radix Murrayae 10-16; Juniperus rigida Sieb.et Zucc. 8-13; Fructus Gardeniae 9-19; Rhizoma Smilacis Chinensis 6-10; Rhizoma Ligustici 6-12; Herba Damnacanthi 9-13; Caulis Bauhiniae Championii 7-12; Fructus Gleditsia veneer 5-12; Herba Siegesbeckiae 10-14; great Ye south Soviet Union 7-15.
2. the Chinese medicine for the treatment of gout as claimed in claim 1, is characterized in that, Cacumen Platycladi 12-14; Rhizoma et Radix Dysosmae Veitchii 8-10; Pallet 11-15; Folium daphnes odorae 13-15; Fructus Liquidambaris 10-15; Radix Murrayae 11-15; Juniperus rigida Sieb.et Zucc. 9-12; Fructus Gardeniae 11-17; Rhizoma Smilacis Chinensis 7-9; Rhizoma Ligustici 8-10; Herba Damnacanthi 10-12; Caulis Bauhiniae Championii 9-10; Fructus Gleditsia veneer 7-10; Herba Siegesbeckiae 11-13; great Ye revives in south 9-13(preferably: Cacumen Platycladi 13; Rhizoma et Radix Dysosmae Veitchii 9; Pallet 13; Folium daphnes odorae 14; Fructus Liquidambaris 12.5; Radix Murrayae 13; Juniperus rigida Sieb.et Zucc. 10.5; Fructus Gardeniae 14; Rhizoma Smilacis Chinensis 8; Rhizoma Ligustici 9; Herba Damnacanthi 11; Caulis Bauhiniae Championii 9.5; Fructus Gleditsia veneer 8.5; Herba Siegesbeckiae 12; great Ye south Soviet Union 11).
3. the Chinese medicine of the treatment gout as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable granule, its preparation method is:
(1) get Rhizoma et Radix Dysosmae Veitchii, Folium daphnes odorae and Fructus Gleditsia veneer removing impurity, be placed in pot, intense fire is heated to surperficial pitchy, Guan Huohou, Rhizoma Zingiberis Recens block is chopped into end, puts into pot, mix thoroughly, and airtight 8-16 minute (preferred: airtight 12 minutes), takes out, pulverize;
(2) get Fructus Liquidambaris and Juniperus rigida Sieb.et Zucc. to clean, be placed in steamer, moderate heat water proof heating 20-30 minute is (preferred: water proof heating 22-28 minute; Be more preferably: water proof heats 25 minutes), take out, be placed in hot pot together with coarse sand, it is yellow that intense fire is heated to medical material surface zoom, and take out, sieve removes coarse sand, smashs to pieces;
(3) Fructus Gardeniae is cleaned remove impurity, add rice vinegar and infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), taking-up is sprinkled into Sal and mixes thoroughly, is placed in parch container, and slow fire is fried to dry, takes out and pulverizes together with step (1) (2) made crude drug;
(4) Cacumen Platycladi, pallet, Radix Murrayae, Rhizoma Smilacis Chinensis, Rhizoma Ligustici, Herba Damnacanthi, Caulis Bauhiniae Championii, Herba Siegesbeckiae and large Ye Nansu remove impurity are cleaned, be placed in marmite, add boiled crude drug quality 6-9 water doubly (preferably: add boiled crude drug quality 7-8 water doubly; Be more preferably: the water adding boiled crude drug quality 7.5 times) decoct, big fire is heated to boiling, turns little fire and decocts, Guan Huohou, collecting by filtration filtrate;
(5) step (4) remaining filtering residue is mixed with step (3) gained medicated powder, add water and again decoct 25 minutes, merge twice gained filtrate, concentrate drying, add adjuvant and pulverize, make graininess, obtain granule.
4. the preparation method of the Chinese medicine granule for the treatment of gout as claimed in claim 3, is characterized in that, it is (preferred: to turn little fire and decoct 32-42 minute that step (4) turns little fire decoction 28-46 minute; Be more preferably: turn little fire and decoct 37 minutes).
5. the Chinese medicine of the treatment gout as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable unguentum, its preparation method is:
(1) get Rhizoma et Radix Dysosmae Veitchii, Folium daphnes odorae and Fructus Gleditsia veneer removing impurity, be placed in pot, intense fire is heated to surperficial pitchy, Guan Huohou, Rhizoma Zingiberis Recens block is chopped into end, puts into pot, mix thoroughly, and airtight 8-16 minute (preferred: airtight 12 minutes), takes out, pulverize;
(2) get Fructus Liquidambaris and Juniperus rigida Sieb.et Zucc. to clean, be placed in steamer, moderate heat water proof heating 20-30 minute is (preferred: water proof heating 22-28 minute; Be more preferably: water proof heats 25 minutes), take out, be placed in hot pot together with coarse sand, it is yellow that intense fire is heated to medical material surface zoom, and take out, sieve removes coarse sand, smashs to pieces;
(3) Fructus Gardeniae is cleaned remove impurity, add rice vinegar and infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), taking-up is sprinkled into Sal and mixes thoroughly, is placed in parch container, and slow fire is fried to dry, takes out and pulverizes together with step (1) (2) made crude drug;
(4) Cacumen Platycladi, pallet, Radix Murrayae, Rhizoma Smilacis Chinensis, Rhizoma Ligustici, Herba Damnacanthi, Caulis Bauhiniae Championii, Herba Siegesbeckiae and large Ye Nansu remove impurity are cleaned, be placed in marmite, add boiled crude drug quality 6-9 water doubly (preferably: add boiled crude drug quality 7-8 water doubly; Be more preferably: the water adding boiled crude drug quality 7.5 times) decoct, big fire is heated to boiling, turns little fire decoction 28-46 minute (preferred: to turn little fire and decoct 32-42 minute; Be more preferably: turn little fire and decoct 37 minutes), Guan Huohou, collecting by filtration filtrate;
(5) by step (3) (4) gained medicated powder and filtrate mixing, heating is concentrated into thick paste, obtains unguentum.
6. the preparation method of the Chinese medicine unguentum for the treatment of gout as claimed in claim 5, is characterized in that, it is (preferred: heating is concentrated into the thick paste that relative density is 1.14-1.20 that step (5) heating is concentrated into the thick paste that relative density is 1.10-1.24; Be more preferably: heating is concentrated into the thick paste that relative density is 1.17).
7. the Chinese medicine of the treatment gout as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get Rhizoma et Radix Dysosmae Veitchii, Folium daphnes odorae and Fructus Gleditsia veneer removing impurity, be placed in pot, intense fire is heated to surperficial pitchy, Guan Huohou, Rhizoma Zingiberis Recens block is chopped into end, puts into pot, mix thoroughly, and airtight 8-16 minute (preferred: airtight 12 minutes), takes out, pulverize;
(2) get Fructus Liquidambaris and Juniperus rigida Sieb.et Zucc. to clean, be placed in steamer, moderate heat water proof heating 20-30 minute is (preferred: water proof heating 22-28 minute; Be more preferably: water proof heats 25 minutes), take out, be placed in hot pot together with coarse sand, it is yellow that intense fire is heated to medical material surface zoom, and take out, sieve removes coarse sand, smashs to pieces;
(3) Fructus Gardeniae is cleaned remove impurity, add rice vinegar and infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), taking-up is sprinkled into Sal and mixes thoroughly, is placed in parch container, and slow fire is fried to dry, takes out and pulverizes together with step (1) (2) made crude drug;
(4) Cacumen Platycladi, pallet, Radix Murrayae, Rhizoma Smilacis Chinensis, Rhizoma Ligustici, Herba Damnacanthi, Caulis Bauhiniae Championii, Herba Siegesbeckiae and large Ye Nansu remove impurity are cleaned, be placed in marmite, add boiled crude drug quality 6-9 water doubly (preferably: add boiled crude drug quality 7-8 water doubly; Be more preferably: the water adding boiled crude drug quality 7.5 times) decoct, big fire is heated to boiling, turns little fire decoction 28-46 minute (preferred: to turn little fire and decoct 32-42 minute; Be more preferably: turn little fire and decoct 37 minutes), Guan Huohou, collecting by filtration filtrate;
(5) spray drying step (4) gained filtrate, mixes dry thing with step (3) made medicated powder, pulverizes and sieves, and adds water generally to make ball, obtains pill.
8. the preparation method of the Chinese medicine pill for the treatment of gout as claimed in claim 7, it is characterized in that, it is (preferred: to pulverize 80-100 mesh sieve that step (5) pulverized 60-120 mesh sieve; Be more preferably: pulverized 90 mesh sieves).
9. the Chinese medicine of the treatment gout as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Rhizoma et Radix Dysosmae Veitchii, Folium daphnes odorae and Fructus Gleditsia veneer removing impurity, be placed in pot, intense fire is heated to surperficial pitchy, Guan Huohou, Rhizoma Zingiberis Recens block is chopped into end, puts into pot, mix thoroughly, and airtight 8-16 minute (preferred: airtight 12 minutes), takes out, pulverize;
(2) get Fructus Liquidambaris and Juniperus rigida Sieb.et Zucc. to clean, be placed in steamer, moderate heat water proof heating 20-30 minute is (preferred: water proof heating 22-28 minute; Be more preferably: water proof heats 25 minutes), take out, be placed in hot pot together with coarse sand, it is yellow that intense fire is heated to medical material surface zoom, and take out, sieve removes coarse sand, smashs to pieces;
(3) Fructus Gardeniae is cleaned remove impurity, add rice vinegar and infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), taking-up is sprinkled into Sal and mixes thoroughly, is placed in parch container, and slow fire is fried to dry, takes out and pulverizes together with step (1) (2) made crude drug;
(4) Cacumen Platycladi, pallet, Radix Murrayae, Rhizoma Smilacis Chinensis, Rhizoma Ligustici, Herba Damnacanthi, Caulis Bauhiniae Championii, Herba Siegesbeckiae and large Ye Nansu remove impurity are cleaned, be placed in marmite, add boiled crude drug quality 6-9 water doubly (preferably: add boiled crude drug quality 7-8 water doubly; Be more preferably: the water adding boiled crude drug quality 7.5 times) decoct, big fire is heated to boiling, turns little fire decoction 28-46 minute (preferred: to turn little fire and decoct 32-42 minute; Be more preferably: turn little fire and decoct 37 minutes), Guan Huohou, collecting by filtration filtrate;
(5) by step (3) (4) gained medicated powder and filtrate mixing, heating is concentrated, dries and pulverizes, obtain powder.
10. the preparation method of the Chinese medicine powder for the treatment of gout as claimed in claim 9, is characterized in that, step (5) is dried and pulverized 120-240 mesh sieve (preferably: pulverized 150-210 mesh sieve; Be more preferably: pulverized 180 mesh sieves).
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103127428A (en) * 2013-03-27 2013-06-05 谢银芳 Chinese patent drug for treatment of gouty arthritis
KR101346281B1 (en) * 2013-08-20 2013-12-31 강영효 Compositions for preventing, improving or treating gout, containing extracts of twenty nine medicine plants as active ingredient

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103127428A (en) * 2013-03-27 2013-06-05 谢银芳 Chinese patent drug for treatment of gouty arthritis
KR101346281B1 (en) * 2013-08-20 2013-12-31 강영효 Compositions for preventing, improving or treating gout, containing extracts of twenty nine medicine plants as active ingredient

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
马吉祥: "《实用临证中药手册》", 30 April 1996, 人民军医出版社 *

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