CN104887965A - Traditional Chinese medicine preparation for treating spondylo-arthritis and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating spondylo-arthritis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating spondylo-arthritis and a preparation method thereof and belongs to the field of traditional Chinese medicines. The active ingredients of the traditional Chinese medicine preparation comprise the following raw materials: Hainan ervatamia root, all-grass of fourfinger rattanpalm, root of hemandialeaf stephania, rhizome of bear's-foot fern, all-grass of oyster mushroom, root of woody hawkbeard, root and rhizome of tartarian buckwheat, rhizome of fourleaf paris, wolfberry fruits, peach twig, maifanitum, herb of passionflower, herba rabdosiae rubescentis, root of twotooth achyranthes, herb of comnon thunia and all-grass of beautiful spotflower. The medicinal materials selected for preparing the traditional Chinese medicine preparation disclosed by the invention are good in compatibility and accord with theories of the traditional Chinese medicine and pharmacology and the modern medicine and pharmacology, so that the traditional Chinese medicine preparation has the effects of activating blood circulation to relieve pain, dispersing blood stasis and eliminating stagnation, and relaxing muscles and tendons to activate collateral flow, has a significant effect on various symptoms caused by osteoarthritis, can avoid relapse after curing, is convenient to take and short in treatment course, is quick to take effect, does not have toxic or side effect, can achieve the aim of treating both symptoms and root causes, is miraculous in effect and practical, and is worthy of clinical extensive popularization and application.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation and preparation method for the treatment of joint of vertebral column inflammation.
Background technology
Joint of vertebral column is scorching, previously also known as seronegative spondyloanthropathy or SpA, this is one group of chronic inflammation rheumatism, there is specific Pathophysiology, clinical, radiology and inherited characteristic, inflammatory lumbago and backache is accompanied or is not accompanied periphery arthritis, and the extra-articular manifestation of certain feature is the distinctive sings and symptoms of this kind of disease in addition.Joint of vertebral column is scorching has very strong dependency with HLA-B27 gene, and this makes its concept obtain good unification.The real concept of seronegative spondyloanthropathy is just clear and definite by Wright etc. before more than ten years.It is relevant that term " seronegative spondyloanthropathy " is used to description one class, has many identical clinical, radiology and serological feature, also have the different substantiality disease of familial and genetic affinity.These diseases comprise ankylosing spondylitis at first, reactive arthritis, Reiter syndrome, the arthrosis that ulcerative colitis is relevant with Crohn disease, Whipple disease and Behcet disease.These diseases have many differences and similarity, comprise rheumatoid factor negative, do not have subcutaneous nodule, and radiologic sacroiliitis is accompanied or do not accompanied periphery arthritis and the familial aggregation of inflammatory.
In all diseases that joint of vertebral column inflammation comprises, B27 antigen all significantly increases.Research confirms that ankylosing spondylitis has similar B27 antigen frequency with reactive arthritis.Inflammatory bowel characteristic of disease arthritic periphery arthritis is the evidence of getting involved outside intestinal, but its B27 antigen presentation does not increase.But the inflammatory bowel characteristic of disease arthritic that spondylitis occurs is but 75% relevant with B27 antigen.These find that the pathogenesis of prompting inflammatory bowel characteristic of disease arthritis knuckle disease is similar to ankylosing spondylitis, and the inflammatory bowel characteristic of disease arthritic carrying HLA-B27 has the high risk developing into ankylosing spondylitis.The incidence rate of simple psoriatic HLA-B27 does not increase, the evidence that periphery psoriasis pustulosa arthritic does not have B27 to increase, but 45% psoriatic spondylitis has B27 antigen, but with ankylosing spondylitis and reactive arthritis obvious attenuating compared with the dependency of B27 antigen.However, these researchs confirm that psoriatic arthritis should be included among joint of vertebral column inflammation.The prompting of these data necessarily has other factors to play effect in the inflammatory arthritis of spinal column.The chronic arthritis of the Juvenile onset of certain forms also should be included in the category of joint of vertebral column inflammation, and few arthropathic child has higher B27 frequency.But Whipple disease and Behcet disease are no longer included in joint of vertebral column inflammation with the dependency of HLA-B27 and the feature with other owing to lacking.
Current treatment joint of vertebral column is scorching, and mainly based on doctor trained in Western medicine and Chinese traditional treatment, although western medical treatment is effective, effect is undesirable, large to gastric irritation, side effect is large, and life-time service patient can not accept, what have then takes operation, and What is more causes paraplegia, more allows patient not accept.Traditional Chinese medical science mainstay thing and massage, acupuncture, the therapies such as cup, existing Chinese Herbs is not ideal, therefore selects a kind of better Chinese medicine preparation to treat joint of vertebral column inflammation.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and preparation method for the treatment of joint of vertebral column inflammation; Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of promoting blood circulation and stopping pain, blood stasis-eliminating and stagnation-dissipating, relaxing muscles and tendons and activating QI and blood in the collateral, to the various symptoms that treatment osteoarthritis causes, there is significant effect, non-relapse after healing, taking convenience, short treating period, instant effect, have no side effect, can reach the object for the treatment of both the principal and secondary aspects of a disease, special effect is practical, wide popularization and application on clinic.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for joint of vertebral column inflammation, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Ervatamiae Hainanensis 55 ~ 78 portions of Herba Calami tetradactylis 47 ~ 76 parts of Radix Stephaniae hemandifoliae 46 ~ 72 portions of Rhizoma Humatae Tyermannis 42 ~ 69 parts
Pick up the ears 42 ~ 68 parts of Radix Crepidis Ligneaes, 39 ~ 67 parts of Radix Et Rhizoma Fagopyri Tatarici, 38 ~ 67 parts of Rhizoma Paridis tetraphyllae 36 ~ 63 parts
Fructus Lycii 31 ~ 59 parts of Ramulus Persicae 29 ~ 57 parts of Maifanitums 26 ~ 56 parts of Herba Passiflorae Caeruleaes 23 ~ 51 parts
Rabdosia rubescens 21 ~ 47 parts of Radix Achyranthis 17 ~ 43 parts of Herba Thuniae Albae 15 ~ 36 parts of Herba Spilanthis callimorphaies 12 ~ 31 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Ervatamiae Hainanensis 59 ~ 75 portions of Herba Calami tetradactylis 51 ~ 71 parts of Radix Stephaniae hemandifoliae 50 ~ 68 portions of Rhizoma Humatae Tyermannis 47 ~ 66 parts
Pick up the ears 46 ~ 64 parts of Radix Crepidis Ligneaes, 43 ~ 62 parts of Radix Et Rhizoma Fagopyri Tatarici, 42 ~ 62 parts of Rhizoma Paridis tetraphyllae 40 ~ 58 parts
Fructus Lycii 36 ~ 55 parts of Ramulus Persicae 33 ~ 52 parts of Maifanitums 31 ~ 51 parts of Herba Passiflorae Caeruleaes 28 ~ 46 parts
Rabdosia rubescens 25 ~ 43 parts of Radix Achyranthis 21 ~ 39 parts of Herba Thuniae Albae 19 ~ 32 parts of Herba Spilanthis callimorphaies 16 ~ 28 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Ervatamiae Hainanensis 64 ~ 72 portions of Herba Calami tetradactylis 56 ~ 66 parts of Radix Stephaniae hemandifoliae 55 ~ 63 portions of Rhizoma Humatae Tyermannis 51 ~ 60 parts
Pick up the ears 51 ~ 59 parts of Radix Crepidis Ligneaes, 48 ~ 57 parts of Radix Et Rhizoma Fagopyri Tatarici, 47 ~ 55 parts of Rhizoma Paridis tetraphyllae 45 ~ 53 parts
Fructus Lycii 41 ~ 49 parts of Ramulus Persicae 37 ~ 48 parts of Maifanitums 36 ~ 46 parts of Herba Passiflorae Caeruleaes 33 ~ 41 parts
Rabdosia rubescens 30 ~ 38 parts of Radix Achyranthis 26 ~ 34 parts of Herba Thuniae Albae 23 ~ 26 parts of Herba Spilanthis callimorphaies 20 ~ 24 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Ervatamiae Hainanensis 68 portions of Herba Calami tetradactylis 61 parts of Radix Stephaniae hemandifoliae 59 portions of Rhizoma Humatae Tyermannis 56 parts
Pick up the ears 55 parts of Radix Crepidis Ligneaes, 52 parts of Radix Et Rhizoma Fagopyri Tatarici, 51 parts of Rhizoma Paridis tetraphyllae 48 parts
Fructus Lycii 45 parts of Ramulus Persicae 43 parts of Maifanitums 41 parts of Herba Passiflorae Caeruleaes 37 parts
Rabdosia rubescens 34 parts of Radix Achyranthis 30 parts of Herba Thuniae Albae 25 parts of Herba Spilanthis callimorphaies 22 parts.
Treat a preparation method for the Chinese medicine preparation of joint of vertebral column inflammation, comprise following processing step:
(1) by Radix Ervatamiae Hainanensis, pick up the ears, Ramulus Persicae and Herba Passiflorae Caeruleae clean, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Herba Calami tetradactyli, Radix Crepidis Ligneae, Radix Et Rhizoma Fagopyri Tatarici, Rabdosia rubescens, Radix Achyranthis, Herba Thuniae Albae and Herba Spilanthis callimorphae are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(3) Radix Stephaniae hemandifoliae, Rhizoma Humatae Tyermanni, Rhizoma Paridis tetraphyllae and Maifanitum are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(4) cleaned by Fructus Lycii, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (4), make capsule, obtain the Chinese medicine preparation of described treatment joint of vertebral column inflammation.
The property of medicine of the present invention's Chinese medicine used is as follows:
Radix Ervatamiae Hainanensis: bitter in the mouth, pungent, cool in nature.Slightly poisonous.Heat-clearing and toxic substances removing, pain relieving, blood pressure lowering.For hypertension, laryngopharynx swelling and pain, rheumatic arthritis, stomachache, dysentery; Mastitis are controlled in external, furuncle and phyma, venom.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " detoxicating and resolving stagnation of pathogens, wind-expelling pain-stopping.Control laryngopharynx swelling and pain, mastitis, rheumatalgia, traumatic injury, cold syndrome of the stomach pain, hypertension.”
Herba Calami tetradactyli: bitter in the mouth is micro-salty, hot in nature, poisonous; Return liver, lung meridian.Diaphoresis is dispeled the wind, promoting blood circulation and hemostasis.Cure mainly anemofrigid cold, rheumatoid arthritis, traumatic injury, amenorrhea, traumatic hemorrhage." Yunnan Chinese herbal medicine " carries: " hemostasis, synthetism, diaphoresis, dispels the wind.”
Radix Stephaniae hemandifoliae: bitter in the mouth, cold in nature; GUIXIN, liver, large intestine channel.Expelling wind and removing dampness, heat-clearing and toxic substances removing.Dispelling the wind and dampness pathogens arthralgia.Heatstroke, dysentery, carbuncle furuncle poison." Guizhou folk medicine " carries: " heat clearing away, evil-wind expelling and dampness removing.Control heatstroke, dysentery, rheumatism.”
Rhizoma Humatae Tyermanni: sweet in the mouth, property is put down; Return lung, liver, spleen channel.To induce sweat lung heat clearing, eliminating damp, detoxifying, tonify deficiency spleen invigorating.Main anemopyretic cold, cough due to consumptive disease, jaundice, stranguria, sore swells and ache, venom.Guangzhou air force " conventional Chinese herbal medicine handbook " carries: " herb: expelling pathogenic wind and eliminating dampness, removing pathogenic heat from blood and inducing diuresis.Control tetanus, rheumatic arthritis, chronic lambago and skelalgia, lumbar muscle strain, hematuria.”
Pick up the ears: acrid in the mouth, sweet, warm in nature; Return liver, kidney channel.Wind-evil dispelling and cold-evil expelling, relaxing muscles and tendons and activating QI and blood in the collateral, kidney invigorating and YANG supporting.Main lumbago and skelalgia, numb hand and foot, grain does not relax, impotence and seminal emission, weakness of the waist and knees." Xinhua's book on Chinese herbal medicine outline " carries: " have the effect such as relaxing muscles and tendons and activating QI and blood in the collateral, wind-evil dispelling and cold-evil expelling, be used for tonic.”
Radix Crepidis Ligneae: taste is micro-sweet, bitter, cool in nature.Spleen invigorating removing food stagnancy, heat-clearing and toxic substances removing, stimulating milk secretion.For infantile malnutrition, hypogalactia, bronchitis, pneumonia, hepatitis, leucorrhea, discharging fresh blood stool, bones and muscles pain, traumatic injury, furuncle carbuncle." choosing of Yunnan Chinese herbal medicine " carries: " nourishing the lung to arrest cough, heat-clearing and toxic substances removing help digestion and regulate the flow of vital energy, lactogenic.Control bronchitis, pneumonia, carbuncle, infantile malnutrition, hypogalactia, conjunctivitis.”
Radix Et Rhizoma Fagopyri Tatarici: sweet in the mouth, property is put down, mild toxicity; Return spleen, stomach, large intestine channel.Spleen invigorating row is stagnant, regulating QI to relieve pain, removing toxic substances and promoting subsidence of swelling.Cure mainly epigastric distending pain, dyspepsia, dysentery, lumbago and skelalgia, traumatic injury, carbuncle malignant boil, lyssodexis." Inner Mongol Chinese herbal medicine " carries: " removing damp and stopping pain, removing toxic substances and promoting subsidence of swelling, stomach invigorating.Control traumatic injury, lumbago and skelalgia, sore and toxic, dyspepsia.”
Rhizoma Paridis tetraphyllae: bitter in the mouth, pungent, warm in nature.Expelling cold and dampness, removing obstruction in the collateral to relieve pain, hemostasia and promoting granulation.Main chronic arthralgia caused by cold-damp, waist cold type of pain, traumatic hemorrhage." herbal classic " carries: " treating disorders in five ZANG-organs pathogen, cold-damp numbness, extremity soreness, knee joint cold type of pain.”
Fructus Lycii: sweet in the mouth, property is put down, and returns liver, kidney channel.Nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.Modern medicine study confirms, Fructus Lycii can strengthen immune function of human body, has blood pressure lowering, blood sugar lowering and lipotropic effect.
Ramulus Persicae: bitter in the mouth, property is put down; GUIXIN, stomach warp.Promoting blood circulation to remove obstruction in the collateral, removing toxic substances parasite killing.Main cardiac and abdominal pain, rheumatic arthritis, lumbago, traumatic injury, skin ulcer tinea." detailed outline " carries: " control the disobedient cardiac and abdominal pain of chronic infectious disease, ward off epidemic disease.”
Maifanitum: sweet in the mouth, warm in nature, nontoxic; Return liver, stomach, kidney channel.Detoxicating and resolving stagnation of pathogens; Removing the necrotic tissue and promoting granulation, except cold damp eliminating, the liver benefiting stomach invigorating, blood circulation promoting and blood stasis dispelling, diuresis fossil, life lengthening.Cure mainly carbuncle carbuncle on the back, acne, eczema, beriberi, miliaria, finger is chapped, chloasma, toothache, oral ulcer, rheumatic arthralgia, lumbago and backache, chronic hepatitis, gastritis, dysentery, diabetes, neurasthenia, wound is red and swollen, hypertension, senile sclerosis of blood vessels, tumor, lithangiuria.
Herba Passiflorae Caeruleae: bitter in the mouth, warm in nature, nontoxic.Except wind, dehumidifying, invigorates blood circulation, pain relieving.Cure mainly headache due to common cold, nasal obstruction watery nasal discharge, rheumatic arthritis, dysmenorrhea, neuralgia, loses eye, dysentery, fracture." Traditional Chinese Medicine in Sichuan will " carries: " except wind heat clearing away, relieving cough and resolving phlegm.Control wind heat giddy, nasal obstruction watery nasal discharge.”
Rabdosia rubescens: bitter in the mouth, sweet, cold nature.Heat-clearing and toxic substances removing, promoting blood circulation and stopping pain.Main laryngopharynx swelling and pain, headache due to common cold, tracheitis, chronic hepatitis, rheumatic arthritis, snake bite and insect sting.
Radix Achyranthis: by silt eliminating impediment, antiinflammatory diuresis, controls gonorrhea, hematuria, women's amenorrhea, lump in the abdomen, rheumatic arthritis, beriberi, dysentery, malaria, diphtheria, carbuncle, traumatic injury.Treatment diphtheria, treatment infantile pneumonia, induced labor." Chinese herbal medicine handbook is commonly used in Shanghai " carries: " diuresis of stimulating the menstrual flow, heat-clearing and toxic substances removing, promoting blood circulation and stopping pain.Control beriberi swelling, arthritis, rheumatalgia, diphtheria, acute/chronic pharyngitis.”
Herba Thuniae Albae: sweet in the mouth, property is put down; Return lung, stomach, kidney channel.Relieving cough and asthma, blood circulation promoting and blood stasis dispelling.Control pneumonia, trachea, bronchitis, gastric and duodenal ulcers, fracture, traumatic injury impairment caused by overstrain." choosing of Simao, Yunnan Chinese herbal medicine " carries: " nourishing YIN and moistening the lung, relieving cough and resolving phlegm.Control pulmonary tuberculosis, pneumonia, tracheobronchitis, gastric and duodenal ulcers.”
Herba Spilanthis callimorphae: acrid in the mouth, hardship, warm in nature, slightly poisonous.Expelling wind and removing dampness, eliminating stasis to stop pain.For fracture, traumatic injury, rheumatic arthritis, stimulates the menstrual flow, cold syndrome of the stomach pain, toothache, cold, traumatic hemorrhage." Yunnan Chinese herbal medicine " carries: " pain relieving, blood circulation promoting and blood stasis dispelling.Control fracture, traumatic injury, rheumatic arthritis, amenorrhea, cold syndrome of the stomach pain.”
The present invention compared with prior art, has following beneficial effect:
Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of promoting blood circulation and stopping pain, blood stasis-eliminating and stagnation-dissipating, relaxing muscles and tendons and activating QI and blood in the collateral, to the various symptoms that treatment osteoarthritis causes, there is significant effect, non-relapse after healing, taking convenience, short treating period, instant effect, have no side effect, can reach the object for the treatment of both the principal and secondary aspects of a disease, special effect is practical, wide popularization and application on clinic.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Radix Ervatamiae Hainanensis 75g Herba Calami tetradactyli 71g Radix Stephaniae hemandifoliae 68g Rhizoma Humatae Tyermanni 66g
Pick up the ears 64g Radix Crepidis Ligneae 62g Radix Et Rhizoma Fagopyri Tatarici 62g Rhizoma Paridis tetraphyllae 58g
Fructus Lycii 55g Ramulus Persicae 52g Maifanitum 51g Herba Passiflorae Caeruleae 46g
Rabdosia rubescens 43g Radix Achyranthis 39g Herba Thuniae Albae 32g Herba Spilanthis callimorphae 28g.
Treat a preparation method for the Chinese medicine preparation of joint of vertebral column inflammation, comprise following processing step:
(1) by Radix Ervatamiae Hainanensis, pick up the ears, Ramulus Persicae and Herba Passiflorae Caeruleae clean, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Herba Calami tetradactyli, Radix Crepidis Ligneae, Radix Et Rhizoma Fagopyri Tatarici, Rabdosia rubescens, Radix Achyranthis, Herba Thuniae Albae and Herba Spilanthis callimorphae are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(3) Radix Stephaniae hemandifoliae, Rhizoma Humatae Tyermanni, Rhizoma Paridis tetraphyllae and Maifanitum are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(4) cleaned by Fructus Lycii, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (4), make capsule, obtain the Chinese medicine preparation of described treatment joint of vertebral column inflammation.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, 2 ~ 4 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Radix Ervatamiae Hainanensis 72g Herba Calami tetradactyli 66g Radix Stephaniae hemandifoliae 63g Rhizoma Humatae Tyermanni 60g
Pick up the ears 59g Radix Crepidis Ligneae 57g Radix Et Rhizoma Fagopyri Tatarici 55g Rhizoma Paridis tetraphyllae 53g
Fructus Lycii 49g Ramulus Persicae 48g Maifanitum 46g Herba Passiflorae Caeruleae 41g
Rabdosia rubescens 38g Radix Achyranthis 34g Herba Thuniae Albae 26g Herba Spilanthis callimorphae 24g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Radix Ervatamiae Hainanensis 68g Herba Calami tetradactyli 61g Radix Stephaniae hemandifoliae 59g Rhizoma Humatae Tyermanni 56g
Pick up the ears 55g Radix Crepidis Ligneae 52g Radix Et Rhizoma Fagopyri Tatarici 51g Rhizoma Paridis tetraphyllae 48g
Fructus Lycii 45g Ramulus Persicae 43g Maifanitum 41g Herba Passiflorae Caeruleae 37g
Rabdosia rubescens 34g Radix Achyranthis 30g Herba Thuniae Albae 25g Herba Spilanthis callimorphae 22g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Radix Ervatamiae Hainanensis 64g Herba Calami tetradactyli 56g Radix Stephaniae hemandifoliae 55g Rhizoma Humatae Tyermanni 51g
Pick up the ears 51g Radix Crepidis Ligneae 48g Radix Et Rhizoma Fagopyri Tatarici 47g Rhizoma Paridis tetraphyllae 45g
Fructus Lycii 41g Ramulus Persicae 37g Maifanitum 36g Herba Passiflorae Caeruleae 33g
Rabdosia rubescens 30g Radix Achyranthis 26g Herba Thuniae Albae 23g Herba Spilanthis callimorphae 20g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Radix Ervatamiae Hainanensis 59g Herba Calami tetradactyli 51g Radix Stephaniae hemandifoliae 50g Rhizoma Humatae Tyermanni 47g
Pick up the ears 46g Radix Crepidis Ligneae 43g Radix Et Rhizoma Fagopyri Tatarici 42g Rhizoma Paridis tetraphyllae 40g
Fructus Lycii 36g Ramulus Persicae 33g Maifanitum 31g Herba Passiflorae Caeruleae 28g
Rabdosia rubescens 25g Radix Achyranthis 21g Herba Thuniae Albae 19g Herba Spilanthis callimorphae 16g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of joint of vertebral column inflammation, select the routine clinical observation of the scorching patient 160 of joint of vertebral column of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 80 example, wherein male 40 example, women 40 example, 20 ~ 67 years old age, 43.5 years old mean age, average course of disease 2 years; Matched group 80 example, wherein male 40 example, women 40 example, 21 ~ 66 years old age, 43.5 years old mean age, average course of disease 2 years.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes Chinese medicine preparation of the present invention, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, 2 ~ 4 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes sulfasalazine, oral, and initial dose is 2 ~ 3g on the one, and points 3 ~ 4 times oral, and the course for the treatment of is depending on the state of an illness.
3, efficacy determination:
(1) cure: cardinal symptom all disappears, joint of vertebral column recovers normal.
(2) effective: cardinal symptom obviously alleviates, joint of vertebral column takes a turn for the better to some extent.
(3) effective: cardinal symptom alleviates to some extent, and joint of vertebral column is clearly better.
(4) invalid: by treating rear cardinal symptom without alleviating or increasing the weight of.
4, result:
| Number of cases | Cure | Effective | Effectively | Invalid | Cure rate | Total effective rate | |
| Treatment group | 80 | 45 | 21 | 12 | 2 | 56.3% | 97.5% |
| Matched group | 80 | 23 | 18 | 11 | 28 | 28.8% | 65% |
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, grandson, female, 28 years old, people from Yangpu District, Shanghai.Patient is rubbed by car because of carelessness, does not have sensation at that time, and can also stand up, also just take it seriously, and spent a period of time afterwards, just sensation joint of vertebral column always pain, and activity is got up also dumb, be often to ache to obtain the waist that directly do not get up.Remove examination in hospital: doctor carries out inspection to it and finds, patient suffers from joint of vertebral column inflammation.Give Chinese medicine preparation of the present invention treatment, after taking 1 course for the treatment of, symptom alleviates, and after continuing to take 2 courses for the treatment of, transference cure, joint of vertebral column recovers normal.
2, Hu, man, 34 years old, Tianjin Dagang District people.It is scorching that joint of vertebral column is suffered from patient's readme, and whenever rainy weather, general joint limitation of activity, does not stiffly relax, heavy unable.Mouth is glutinous, and xerostomia happiness drink, two is just normal.Tongue has indentation, and tongue is partially yellow, stringy and thready pulse.Take Chinese medicine preparation of the present invention treatment, after taking 1 course for the treatment of, symptom takes a turn for the better to some extent, and after continuing to take 2 courses for the treatment of, transference cure, joint recovers normal, follows up a case by regular visits to without recurrence after half a year.
3, high certain, female, 40 years old, Heilungkiang Suihua people.Patient suffers from that joint of vertebral column is scorching more than 3 years, and spinal column gross distortion, cannot walk, and uses multiple Drug therapy, and because side effects of pharmaceutical drugs cause gastropathy, hypertension, heart also has problem, takes medicine blood pressure lowering everyday.Give Chinese medicine preparation of the present invention treatment, after taking 1 course for the treatment of, symptom is clearly better, and after taking 3 courses for the treatment of, symptom all disappears, and physical recovery is normal, follows up a case by regular visits to without recurrence after 1 year.
4, Zhu, man, 55 years old, people from Fuling Chongqing.Patient's readme, spinal pain 2 years, removes examination in hospital; be diagnosed as " joint of vertebral column is scorching ", used multiple method to treat, and all had no improvement; even increase the weight of, again check, give Chinese medicine preparation of the present invention treatment; after taking 1 course for the treatment of; spinal pain symptom is clearly better, and after continuing to take 3 courses for the treatment of, symptom all disappears; energy normal activity, follows up a case by regular visits to and does not recur so far.
5, Lin, female, 63 years old, people from Yingkou, Liaoning.Patient suffers from joint of vertebral column inflammation for many years, uses multiple Drug therapy, and all has no improvement.I treated at institute afterwards, and give Chinese medicine preparation of the present invention treatment, after taking 1 course for the treatment of, symptom takes a turn for the better to some extent, and after continuing to take 2 courses for the treatment of, transference cure, recovers locomotor activity, follows up a case by regular visits to without recurrence after 2 years.
6, certain is thanked, man, 67 years old, people from Cangzhou, Hebei.Patient's spinal pain 2 years, the rainy day, the pain increased, and night more so, is diagnosed as joint of vertebral column inflammation on inspection.Adopt Chinese medicine preparation of the present invention to treat, after taking 1 course for the treatment of, symptom is obviously eliminated, after continuing to take 3 courses for the treatment of, symptom completely without, recover orthobiosis, follow up a case by regular visits to after 1 year without recurrence.
Claims (5)
1. treat a Chinese medicine preparation for joint of vertebral column inflammation, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Ervatamiae Hainanensis 55 ~ 78 portions of Herba Calami tetradactylis 47 ~ 76 parts of Radix Stephaniae hemandifoliae 46 ~ 72 portions of Rhizoma Humatae Tyermannis 42 ~ 69 parts
Pick up the ears 42 ~ 68 parts of Radix Crepidis Ligneaes, 39 ~ 67 parts of Radix Et Rhizoma Fagopyri Tatarici, 38 ~ 67 parts of Rhizoma Paridis tetraphyllae 36 ~ 63 parts
Fructus Lycii 31 ~ 59 parts of Ramulus Persicae 29 ~ 57 parts of Maifanitums 26 ~ 56 parts of Herba Passiflorae Caeruleaes 23 ~ 51 parts
Rabdosia rubescens 21 ~ 47 parts of Radix Achyranthis 17 ~ 43 parts of Herba Thuniae Albae 15 ~ 36 parts of Herba Spilanthis callimorphaies 12 ~ 31 parts.
2. a kind of Chinese medicine preparation for the treatment of joint of vertebral column inflammation according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Ervatamiae Hainanensis 59 ~ 75 portions of Herba Calami tetradactylis 51 ~ 71 parts of Radix Stephaniae hemandifoliae 50 ~ 68 portions of Rhizoma Humatae Tyermannis 47 ~ 66 parts
Pick up the ears 46 ~ 64 parts of Radix Crepidis Ligneaes, 43 ~ 62 parts of Radix Et Rhizoma Fagopyri Tatarici, 42 ~ 62 parts of Rhizoma Paridis tetraphyllae 40 ~ 58 parts
Fructus Lycii 36 ~ 55 parts of Ramulus Persicae 33 ~ 52 parts of Maifanitums 31 ~ 51 parts of Herba Passiflorae Caeruleaes 28 ~ 46 parts
Rabdosia rubescens 25 ~ 43 parts of Radix Achyranthis 21 ~ 39 parts of Herba Thuniae Albae 19 ~ 32 parts of Herba Spilanthis callimorphaies 16 ~ 28 parts.
3. a kind of Chinese medicine preparation for the treatment of joint of vertebral column inflammation according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Ervatamiae Hainanensis 64 ~ 72 portions of Herba Calami tetradactylis 56 ~ 66 parts of Radix Stephaniae hemandifoliae 55 ~ 63 portions of Rhizoma Humatae Tyermannis 51 ~ 60 parts
Pick up the ears 51 ~ 59 parts of Radix Crepidis Ligneaes, 48 ~ 57 parts of Radix Et Rhizoma Fagopyri Tatarici, 47 ~ 55 parts of Rhizoma Paridis tetraphyllae 45 ~ 53 parts
Fructus Lycii 41 ~ 49 parts of Ramulus Persicae 37 ~ 48 parts of Maifanitums 36 ~ 46 parts of Herba Passiflorae Caeruleaes 33 ~ 41 parts
Rabdosia rubescens 30 ~ 38 parts of Radix Achyranthis 26 ~ 34 parts of Herba Thuniae Albae 23 ~ 26 parts of Herba Spilanthis callimorphaies 20 ~ 24 parts.
4. a kind of Chinese medicine preparation for the treatment of joint of vertebral column inflammation according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Ervatamiae Hainanensis 68 portions of Herba Calami tetradactylis 61 parts of Radix Stephaniae hemandifoliae 59 portions of Rhizoma Humatae Tyermannis 56 parts
Pick up the ears 55 parts of Radix Crepidis Ligneaes, 52 parts of Radix Et Rhizoma Fagopyri Tatarici, 51 parts of Rhizoma Paridis tetraphyllae 48 parts
Fructus Lycii 45 parts of Ramulus Persicae 43 parts of Maifanitums 41 parts of Herba Passiflorae Caeruleaes 37 parts
Rabdosia rubescens 34 parts of Radix Achyranthis 30 parts of Herba Thuniae Albae 25 parts of Herba Spilanthis callimorphaies 22 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the Chinese medicine preparation of joint of vertebral column inflammation, it is characterized in that: comprise following processing step:
(1) by Radix Ervatamiae Hainanensis, pick up the ears, Ramulus Persicae and Herba Passiflorae Caeruleae clean, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Herba Calami tetradactyli, Radix Crepidis Ligneae, Radix Et Rhizoma Fagopyri Tatarici, Rabdosia rubescens, Radix Achyranthis, Herba Thuniae Albae and Herba Spilanthis callimorphae are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(3) Radix Stephaniae hemandifoliae, Rhizoma Humatae Tyermanni, Rhizoma Paridis tetraphyllae and Maifanitum are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(4) cleaned by Fructus Lycii, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (4), make capsule, obtain the Chinese medicine preparation of described treatment joint of vertebral column inflammation.
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| CN106266823A (en) * | 2016-08-22 | 2017-01-04 | 刘秋云 | A kind of the combinat ion of Traditional Chinese Medicine and Pharmacy with Western Pharmacy preparation treating joint of vertebral column inflammation and preparation method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258696A (en) * | 2011-07-05 | 2011-11-30 | 吴斌 | Compound traditional Chinese medicine for treating undifferentiated spondyloarthropathy (uSpA) and application thereof |
| CN103877428A (en) * | 2014-04-19 | 2014-06-25 | 李凌 | Medicament for treating osteoarthritis and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102258696A (en) * | 2011-07-05 | 2011-11-30 | 吴斌 | Compound traditional Chinese medicine for treating undifferentiated spondyloarthropathy (uSpA) and application thereof |
| CN103877428A (en) * | 2014-04-19 | 2014-06-25 | 李凌 | Medicament for treating osteoarthritis and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106266823A (en) * | 2016-08-22 | 2017-01-04 | 刘秋云 | A kind of the combinat ion of Traditional Chinese Medicine and Pharmacy with Western Pharmacy preparation treating joint of vertebral column inflammation and preparation method |
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Application publication date: 20150909 |