CN104873939A - Antidiarrheal agent and preparation method thereof - Google Patents
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Abstract
The invention provides an antidiarrheal agent and a preparation method thereof. The antidiarrheal agent consists of the raw materials of kudzuvine root, elecampane, purslane, agastache rugosus, baked ginger, roxburgh rose root, fructus amomi, fructus galangae, limonite, semen plantaginis, rosa laevigata, grifola, phoenix-tail fern, cinnamomum cassia and pea. The antidiarrheal agent can treat continuous diarrhea caused by deficient spleen and weak vital energy through the kudzuvine root, the fructus amomi, the pea and the baked ginger, can treat diarrhea caused by food retention through the elecampane, the roxburgh rose root, the fructus galangae and the like, and can also treat the symptom continuous chronic diarrhea caused by long-term chronic gastrointestinal discomfort through the rosa laevigata and the limonite. The antidiarrheal agent provided by the invention can treat diarrhea caused by various pathogenesises in multiple aspects, and is obvious in treatment effect and short in treatment course, relapse can be avoided, and discomfort of other parts of the body can also be avoided.
Description
Technical field
The present invention relates to the field of Chinese medicines, more specifically, relate to a kind of antidiarrheal and preparation method thereof.
Background technology
Diarrhoea is a kind of common sympton, be commonly called as " diarrhoea ", so-called diarrhoea refers to the frequency that defecation frequency is obviously accustomed on ordinary days, excrement matter is thin, moisture increases, every day, feces volume was more than 200g, or containing non-digest food or pus and blood, mucus, diarrhoea often with symptoms such as defecation urgency sense, anus discomfort, incontinences.Diarrhoea point acute and chronic two classes.Sharply, the course of disease is within 2-3 week, and pathogenic factor comprises bacteriological infection, viral infection, alimentary toxicosis, raw and cold food, food entrapment and catches a cold in acute diarrhea morbidity.Chronic diarrhea morbidity the course of disease more than two months or 2-4 all in recurrent diarrhoea, pathogenic factor complexity, possible pathogenic factor has intestinal infection disease, intestinal non-infectious inflammation, tumor or intestinal malabsorption etc.Diarrhoea not only affects the live and work of people, and long-time diarrhoea also can cause very large harm to human body, and such as, in body, moisture and trace element run off in a large number.
The traditional Chinese medical science is thought, the cause of disease of diarrhoea has endogenous cause of ill and exopathogenic factor two aspect.Exopathogenic factor is mainly the heresy experiencing six climate exopathogens, wherein with the reasons such as cold-damp summer-heat cause comparatively common, be secondly that appetite is hindered, seven emotions discord, affect transformation and transportation of the spleen and stomach, cause spleen and stomach function not normal and suffer from diarrhoea; Endogenous cause of ill is then the closest with insufficiency of the spleen relation, and the diarrhoea caused by Liver and kidney factor, also is mostly be based upon on insufficiency of the spleen basis to produce.
At present, if the object of the drug main for the treatment of diarrhoea by suppressing pathogenic bacterium to reach treatment diarrhoea, although the good effect for the treatment of, easily repeatedly, radical rate is low for the state of an illness.Treatment diarrhoea can also adopt the mode of oral anti-inflammatory drug or injection to treat, although instant effect, side effects of pharmaceutical drugs are obvious, have larger impact to human body.Treatment diarrhoea can also adopt medicine for external use, but great majority exist that therapeutic effect is undesirable, obstinate, cost are higher, the course for the treatment of is longer, the problem of producing effects slowly etc.
Summary of the invention
The object of this invention is to provide a kind of antidiarrheal and preparation method thereof, to solve the unconspicuous problem of curative effect described in background technology.
In order to solve the problems of the technologies described above, the invention provides following technical scheme:
A kind of antidiarrheal, described antidiarrheal by raw material be Radix Puerariae, the Radix Aucklandiae, Herba Portulacae, Herba Pogostemonis, Rhizoma Zingiberis Preparatum, Radix Rosae Normalis, Fructus Amomi, Fructus Galangae, Limonitum, Semen Plantaginis, Fructus Rosae Laevigatae, Polyporus, Herba Pteridis Multifidae, Cortex Cinnamomi, Semen Pisi sativi form.
Preferably, the quality of described antidiarrheal Raw is Radix Puerariae 2-15g, Radix Aucklandiae 2-15g, Herba Portulacae 5-10g, Herba Pogostemonis 10-18g, Rhizoma Zingiberis Preparatum 5-12g, Radix Rosae Normalis 10-20g, Fructus Amomi 30-50g, Fructus Galangae 15-20g, Limonitum 5-25g, Semen Plantaginis 10-30g, Fructus Rosae Laevigatae 15-35g, Polyporus 5-25g, Herba Pteridis Multifidae 2-10g, Cortex Cinnamomi 10-20g, Semen Pisi sativi 8-15g.
Preferably, the quality of described antidiarrheal Raw is Radix Puerariae 2-8g, Radix Aucklandiae 10-15g, Herba Portulacae 8-10g, Herba Pogostemonis 10-14g, Rhizoma Zingiberis Preparatum 5-8g, Radix Rosae Normalis 10-15g, Fructus Amomi 30-40g, Fructus Galangae 18-20g, Limonitum 18-25g, Semen Plantaginis 20-30g, Fructus Rosae Laevigatae 15-25g, Polyporus 5-10g, Herba Pteridis Multifidae 2-5g, Cortex Cinnamomi 10-15g, Semen Pisi sativi 8-12g.
Preferably, the quality of described antidiarrheal Raw is Radix Puerariae 2g, Radix Aucklandiae 15g, Herba Portulacae 5g, Herba Pogostemonis 18g, Rhizoma Zingiberis Preparatum 7g, Radix Rosae Normalis 12g, Fructus Amomi 30g, Fructus Galangae 20g, Limonitum 25g, Semen Plantaginis 30g, Fructus Rosae Laevigatae 25g, Polyporus 10g, Herba Pteridis Multifidae 2g, Cortex Cinnamomi 12g, Semen Pisi sativi 10g.
A preparation method for antidiarrheal, the preparation process of described antidiarrheal is:
S01: by Radix Puerariae, the Radix Aucklandiae, Herba Portulacae, Herba Pogostemonis, Rhizoma Zingiberis Preparatum, Radix Rosae Normalis, Fructus Amomi, Fructus Galangae, Limonitum, Semen Plantaginis, Fructus Rosae Laevigatae, Polyporus, Herba Pteridis Multifidae, Cortex Cinnamomi and Semen Pisi sativi roguing, cleans, and dries;
S02: weigh according to the raw material weight of the oven dry of any one in formula;
S03: the Radix Puerariae after weighing, the Radix Aucklandiae, Herba Portulacae, Herba Pogostemonis, Rhizoma Zingiberis Preparatum, Radix Rosae Normalis, Fructus Amomi, Fructus Galangae, Limonitum, Semen Plantaginis, Fructus Rosae Laevigatae, Polyporus, Herba Pteridis Multifidae, Cortex Cinnamomi and Semen Pisi sativi are cut into small pieces;
S04: be positioned in water by the medical material cut in step S03 and soak half an hour, then heated and boiled, keeps slight boiling condition 30 minutes, and filter after decocting, filtrate is for subsequent use; Add a small amount of water in filtering residue again and carry out decoction 20 minutes, after decoction, filter out filtering residue, filtrate is for subsequent use;
S05: twice filtrate in step S04 is combined, and again filters, obtain medicinal liquid.
In antidiarrheal provided by the invention, the effect of each raw material is as follows:
Radix Puerariae: acrid in the mouth, sweet, property is put down, and has effect of expelling pathogenic factors from muscles for reducing heat, rash, promoting the production of body fluid to quench thirst, yang invigorating antidiarrheal, cures mainly exterior syndrome heating, stiff nape and back, measles without adequate eruption, calentura is thirsty, the deficiency of YIN is quenched one's thirst, diarrhea of heat type hematodiarrhoea, diarrhea due to hypofunction of the spleen.
The Radix Aucklandiae: acrid in the mouth, warm in nature, there is effect of promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion, weigh after curing mainly the breast side of body, abdominal distention, dysentery, food stagnation does not disappear, anorexia.
Herba Portulacae: sour in the mouth, cold in nature, there is effect of heat-clearing and toxic substances removing, cooling blood for hemostasis, dysentery relieving, cure mainly toxic-heat and blood stasis, carbuncle furuncle, eczema, erysipelas, snake bite and insect sting, have blood in stool, hemorrhoidal bleeding, metrostaxis.
Herba Pogostemonis: acrid in the mouth, warm in nature, have removing dampness be amusing, ward off dirty and in, expelling summer-heat, effect of delivering, cure mainly dampness taste, distension and fullness in the abdomen, hygropyrexia coerced from the beginning of, vomiting, breast, have loose bowels, heat-damp in summer, fever with chills.
Rhizoma Zingiberis Preparatum: acrid in the mouth, hot in nature, there is effect of warming the meridian for stopping bleeding, warming middle-JIAO to relieve pain, cure mainly that yang deficiency is lost blood, Deficiency and coldness of spleen and stomach, stomachache vomits and diarrhoea.
Radix Rosae Normalis: sweet in the mouth, acid, property is put down, and cures mainly stomach invigorating, helps digestion, antidiarrheal, dysentery, leukorrhagia, chronic cough.
Fructus Amomi: removing dampness appetizing, warming spleen and stopping diarrha, antiabortive turbid damp obstructing in middle-JIAO of regulating the flow of vital energy, gastral cavity painful abdominal mass are not hungry, Deficiency and coldness of spleen and stomach, vomiting are had loose bowels, frequent fetal movement.
Fructus Galangae: acrid in the mouth, warm in nature, there is cold expelling dampness, effect helped digestion of being amusing, cure mainly coldness and pain in the epigastrium, food stagnation distension, vomiting and diarrhoea, drinking too much.
Limonitum: sweet in the mouth, puckery, cold nature, has relieving diarrhea with astringents, anastaltic effect, cures mainly chronic diarrhea chronic dysentery, fecal blood, bleeding not during menses.
Semen Plantaginis: sweet in the mouth, cold in nature, have that clearing away heat and promoting diuresis is treating stranguria, eliminating dampness by diuresis antidiarrheal, improving eyesight, the effect of eliminating the phlegm, cure mainly the puckery pain of pyretic stranguria, edema distension, diarrhea due to summer heat and dampness, conjunctival congestion and swelling pain, phlegm-heat cough.
Fructus Rosae Laevigatae: sweet in the mouth, acid, puckery, property is put down, and has effect of controlling nocturnal emission with astringent drugs reducing urination, stopping metrorrhagia and leukorrhagia, relieving diarrhea with astringents, cures mainly emission and spermatorrhea, enuresis frequent micturition, chronic diarrhea chronic dysentery.
Polyporus: sweet in the mouth, property is put down, and has effect of promoting diuresis to eliminate damp pathogen, cures mainly dysuria, edema, has loose bowels, stranguria with turbid discharge, leukorrhagia.
Herba Pteridis Multifidae: nature and flavor bitter cold, has effect of clearing away heat-damp and promoting diuresis, subduing swelling and detoxicating, cooling blood for hemostasis.
Cortex Cinnamomi: sweet in the mouth, pungent, hot in nature, have and mend that fire is supporing yang, effect of guiding fire to origin, dispersing cold for relieving pain, promoting the flow of QI-blood by warming the meridian, cure mainly sexual impotence cold womb, chills and pain of the waist and kness, suffer from a deficiency of the kidney breathe heavily, deficiency and coldness vomits and diarrhoea.
Semen Pisi sativi: sweet in the mouth, property is put down, and has gas in benefit, antidiarrheal dysentery, adjusts that battalion defends, effect of diuresis, subduing inflammation, solution mammary calculus poison, cure mainly deficiency of the spleen causing weakness of QI, vomiting and diarrhoea, incoordination between the spleen and stomach.
It is more than that antidiarrheal provided by the invention can treat by Radix Puerariae, Fructus Amomi, Semen Pisi sativi, Rhizoma Zingiberis Preparatum the diarrhoea caused because of deficiency of the spleen causing weakness of QI, can also treat by the Radix Aucklandiae, Radix Rosae Normalis, Fructus Galangae etc. the diarrhoea caused because of food stagnation, also can be treated the disease of the incessant chronic diarrhea caused because of long-term chronic gastrointestinal upset by Fructus Rosae Laevigatae, Limonitum.Antidiarrheal provided by the invention can the diarrhoea that causes of the various cause of disease of many-sided treatment, and therapeutic effect obviously, short treating period, not recur, but also the discomfort at other positions of health can not be caused.
Accompanying drawing explanation
In order to be illustrated more clearly in the technical scheme in the embodiment of the present invention, below the accompanying drawing used required in describing embodiment is briefly described, apparently, for those of ordinary skills, under the prerequisite not paying creative work, other accompanying drawing can also be obtained according to these accompanying drawings.
The preparation flow figure of the antidiarrheal that Fig. 1 provides for the embodiment of the present invention.
Detailed description of the invention
Antidiarrheal that the embodiment of the present invention provides and preparation method thereof, solves the unconspicuous problem of curative effect.
Technical scheme in the embodiment of the present invention is understood better in order to make those skilled in the art person, and enable the above-mentioned purpose of the embodiment of the present invention, feature and advantage become apparent more, below in conjunction with accompanying drawing, the technical scheme in the embodiment of the present invention is described in further detail.
The preparation process of the preparation method of antidiarrheal provided by the invention please refer to accompanying drawing 1.
Embodiment 1
The consisting of of each raw material in the antidiarrheal that the embodiment of the present invention provides:
Radix Puerariae 2g, Radix Aucklandiae 15g, Herba Portulacae 5g, Herba Pogostemonis 18g, Rhizoma Zingiberis Preparatum 7g, Radix Rosae Normalis 12g, Fructus Amomi 30g, Fructus Galangae 20g, Limonitum 25g, Semen Plantaginis 30g, Fructus Rosae Laevigatae 25g, Polyporus 10g, Herba Pteridis Multifidae 2g, Cortex Cinnamomi 12g, Semen Pisi sativi 10g.
The preparation process of the preparation method of the antidiarrheal that the embodiment of the present invention provides is:
S101: by Radix Puerariae, the Radix Aucklandiae, Herba Portulacae, Herba Pogostemonis, Rhizoma Zingiberis Preparatum, Radix Rosae Normalis, Fructus Amomi, Fructus Galangae, Limonitum, Semen Plantaginis, Fructus Rosae Laevigatae, Polyporus, Herba Pteridis Multifidae, Cortex Cinnamomi and Semen Pisi sativi roguing, cleans, and dries;
S102: weigh according to the raw material weight of the oven dry of any one in formula;
S103: the Radix Puerariae after weighing, the Radix Aucklandiae, Herba Portulacae, Herba Pogostemonis, Rhizoma Zingiberis Preparatum, Radix Rosae Normalis, Fructus Amomi, Fructus Galangae, Limonitum, Semen Plantaginis, Fructus Rosae Laevigatae, Polyporus, Herba Pteridis Multifidae, Cortex Cinnamomi and Semen Pisi sativi are cut into small pieces;
S104: be positioned in water by the medical material cut in step S03 and soak half an hour, then heated and boiled, keeps slight boiling condition 30 minutes, and filter after decocting, filtrate is for subsequent use; Add a small amount of water in filtering residue again and carry out decoction 20 minutes, after decoction, filter out filtering residue, filtrate is for subsequent use;
S105: twice filtrate in step S04 is combined, and again filters, obtain medicinal liquid.
Embodiment 2
The consisting of of each raw material in the antidiarrheal that the embodiment of the present invention provides:
Radix Puerariae 8g, Radix Aucklandiae 10g, Herba Portulacae 8g, Herba Pogostemonis 10g, Rhizoma Zingiberis Preparatum 5g, Radix Rosae Normalis 20g, Fructus Amomi 50g, Fructus Galangae 15g, Limonitum 5g, Semen Plantaginis 20g, Fructus Rosae Laevigatae 15g, Polyporus 25g, Herba Pteridis Multifidae 10g, Cortex Cinnamomi 20g, Semen Pisi sativi 8g.
The preparation process of the preparation method of the antidiarrheal that the embodiment of the present invention provides is with embodiment 1.
Embodiment 3
The consisting of of each raw material in the antidiarrheal that the embodiment of the present invention provides:
Radix Puerariae 15g, Radix Aucklandiae 2g, Herba Portulacae 10g, Herba Pogostemonis 14g, Rhizoma Zingiberis Preparatum 8g, Radix Rosae Normalis 10g, Fructus Amomi 40g, Fructus Galangae 18g, Limonitum 18g, Semen Plantaginis 10g, Fructus Rosae Laevigatae 35g, Polyporus 5g, Herba Pteridis Multifidae 5g, Cortex Cinnamomi 10g, Semen Pisi sativi 15g.
The preparation process of the preparation method of the antidiarrheal that the embodiment of the present invention provides is with embodiment 1.
Embodiment 4
The consisting of of each raw material in the antidiarrheal that the embodiment of the present invention provides:
Radix Puerariae 12g, Radix Aucklandiae 8g, Herba Portulacae 6g, Herba Pogostemonis 12g, Rhizoma Zingiberis Preparatum 12g, Radix Rosae Normalis 15g, Fructus Amomi 35g, Fructus Galangae 17g, Limonitum 15g, Semen Plantaginis 18g, Fructus Rosae Laevigatae 20g, Polyporus 12g, Herba Pteridis Multifidae 8g, Cortex Cinnamomi 15g, Semen Pisi sativi 12g.
The preparation process of the preparation method of the antidiarrheal that the embodiment of the present invention provides is with embodiment 1.
Embodiment 5
The consisting of of each raw material in the antidiarrheal that the embodiment of the present invention provides:
Radix Puerariae 13g, Radix Aucklandiae 14g, Herba Portulacae 9g, Herba Pogostemonis 13g, Rhizoma Zingiberis Preparatum 7g, Radix Rosae Normalis 18g, Fructus Amomi 33g, Fructus Galangae 16g, Limonitum 20g, Semen Plantaginis 25g, Fructus Rosae Laevigatae 22g, Polyporus 8g, Herba Pteridis Multifidae 4g, Cortex Cinnamomi 13g, Semen Pisi sativi 9g.
The preparation process of the preparation method of the antidiarrheal that the embodiment of the present invention provides is with embodiment 1.
Clinical trial
The routine diarrhea patient of random selecting 100, the age 15-45 year between, the course of disease is the shortest 5 days, and the longest is 2 months, be divided at random test group 50 example, matched group 50 example.
Diagnostic criteria
1, soft stools or as water sample, increased frequency, can with diseases such as abdominal distention stomachache;
2, acute onset of cruelly letting out is unexpected, and the course of disease is short, can with the disease such as aversion to cold, heating;
3, chronic chronic diarrhea onset is slow, and the course of disease is longer, recurrent exerbation, time light time heavy;
4, improper diet, can bring out by cold and cool or emotion changes;
5, stool routine examination red, leukocyte a little as seen, stool cultivates pathogenic bacterium positive or negative.
Usage and dosage
Test group: according to the formulated medicament of embodiment 1, potion on the one, decocting twice extracting juice 400ml, point morning, late twice empty stomach decoction being taken warmly.Within five days, be a course for the treatment of, treatments period is avoided cold and uncooked food the thing of pungent stimulation.
Matched group: every day is oral rushes down vertical stopping.Within five days, be a course for the treatment of, treatments period is avoided cold and uncooked food the thing of pungent stimulation.
Criterion of therapeutical effect
1, cure: stool is normal, and other transference cures, Clinical Laboratory is normal.
2, effective: times of defecation obviously reduces, other symptoms are improved.
3, invalid: symptom has no improvement.
Therapeutic effect
After the treatment of a course for the treatment of, therapeutic effect lists in table 1.
Table 1: result of the test
| Cure | Effectively | Invalid | |
| Test group | 86％ | 12％ | 2％ |
| Matched group | 74％ | 20％ | 6％ |
Can find out that the cure rate of test group is 86% by result of the test, total effective rate is 98%, cure rate and total effective rate are all apparently higher than matched group, it is more than that this illustrates that Radix Puerariae in antidiarrheal provided by the invention, Fructus Amomi, Semen Pisi sativi, Rhizoma Zingiberis Preparatum can treat the diarrhoea caused because of deficiency of the spleen causing weakness of QI, can also treat by the Radix Aucklandiae, Radix Rosae Normalis, Fructus Galangae etc. the diarrhoea caused because of food stagnation, also can be treated the disease of the incessant chronic diarrhea caused because of long-term chronic gastrointestinal upset by Fructus Rosae Laevigatae, Limonitum.Antidiarrheal provided by the invention can the diarrhoea that causes of the various cause of disease of many-sided treatment, and therapeutic effect obviously, short treating period, not recur, but also the discomfort at other positions of health can not be caused.
Above-described embodiment of the present invention, does not form limiting the scope of the present invention.Any amendment done within the spirit and principles in the present invention, equivalent replacement and improvement etc., all should be included within protection scope of the present invention.
Claims (5)
1. an antidiarrheal, is characterized in that, described antidiarrheal is that Radix Puerariae, the Radix Aucklandiae, Herba Portulacae, Herba Pogostemonis, Rhizoma Zingiberis Preparatum, Radix Rosae Normalis, Fructus Amomi, Fructus Galangae, Limonitum, Semen Plantaginis, Fructus Rosae Laevigatae, Polyporus, Herba Pteridis Multifidae, Cortex Cinnamomi and Semen Pisi sativi form by raw material.
2. antidiarrheal according to claim 1, it is characterized in that, the quality of described antidiarrheal Raw is Radix Puerariae 2-15g, Radix Aucklandiae 2-15g, Herba Portulacae 5-10g, Herba Pogostemonis 10-18g, Rhizoma Zingiberis Preparatum 5-12g, Radix Rosae Normalis 10-20g, Fructus Amomi 30-50g, Fructus Galangae 15-20g, Limonitum 5-25g, Semen Plantaginis 10-30g, Fructus Rosae Laevigatae 15-35g, Polyporus 5-25g, Herba Pteridis Multifidae 2-10g, Cortex Cinnamomi 10-20g, Semen Pisi sativi 8-15g.
3. antidiarrheal according to claim 2, it is characterized in that, the quality of described antidiarrheal Raw is Radix Puerariae 2-8g, Radix Aucklandiae 10-15g, Herba Portulacae 8-10g, Herba Pogostemonis 10-14g, Rhizoma Zingiberis Preparatum 5-8g, Radix Rosae Normalis 10-15g, Fructus Amomi 30-40g, Fructus Galangae 18-20g, Limonitum 18-25g, Semen Plantaginis 20-30g, Fructus Rosae Laevigatae 15-25g, Polyporus 5-10g, Herba Pteridis Multifidae 2-5g, Cortex Cinnamomi 10-15g, Semen Pisi sativi 8-12g.
4. antidiarrheal according to claim 3, it is characterized in that, the quality of described antidiarrheal Raw is Radix Puerariae 2g, Radix Aucklandiae 15g, Herba Portulacae 5g, Herba Pogostemonis 18g, Rhizoma Zingiberis Preparatum 7g, Radix Rosae Normalis 12g, Fructus Amomi 30g, Fructus Galangae 20g, Limonitum 25g, Semen Plantaginis 30g, Fructus Rosae Laevigatae 25g, Polyporus 10g, Herba Pteridis Multifidae 2g, Cortex Cinnamomi 12g, Semen Pisi sativi 10g.
5. a preparation method for antidiarrheal, is characterized in that, the preparation process of described antidiarrheal is:
S01: by Radix Puerariae, the Radix Aucklandiae, Herba Portulacae, Herba Pogostemonis, Rhizoma Zingiberis Preparatum, Radix Rosae Normalis, Fructus Amomi, Fructus Galangae, Limonitum, Semen Plantaginis, Fructus Rosae Laevigatae, Polyporus, Herba Pteridis Multifidae, Cortex Cinnamomi and Semen Pisi sativi roguing, cleans, and dries;
S02: weigh according to the raw material weight of the oven dry of any one in claim 2-4;
S03: the Radix Puerariae after weighing, the Radix Aucklandiae, Herba Portulacae, Herba Pogostemonis, Rhizoma Zingiberis Preparatum, Radix Rosae Normalis, Fructus Amomi, Fructus Galangae, Limonitum, Semen Plantaginis, Fructus Rosae Laevigatae, Polyporus, Herba Pteridis Multifidae, Cortex Cinnamomi and Semen Pisi sativi are cut into small pieces;
S04: the medical material cut in step S03 is positioned in water and decocts, filter after decocting, filtrate is for subsequent use; Filtering residue adds water and again decocts and filter, and filtrate is for subsequent use;
S05: twice filtrate in step S04 is merged, and filtration obtains medicine juice again.
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Cited By (1)
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| WO2009063499A2 (en) * | 2007-09-20 | 2009-05-22 | Desai Atul M | A herbomineral formulation for treating sickle cell disease |
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Application publication date: 20150902 |