CN104027766A - Traditional Chinese medicine composition for treating uraemia - Google Patents
Traditional Chinese medicine composition for treating uraemia Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for treating uraemia. The medicament comprises twelve traditional Chinese medicines namely semen pharbitidis, oriental waterplantain rhizome, calcined dragon bone, pagodatree flower bud, rhubarb, ginger, manchurian wildginger, ginseng, Chinese dodder seed, cherokee rose fruit, herba epimedii and malaytea scurfpea fruit. After water decoction of medicaments is taken, the medicaments mainly pass through the liver and kidneys from the spleen and stomach, have the effects of strengthening the spleen and invigorating the kidneys, warming yang and tonifying qi, eliminating turbid fluid and removing toxicity, promoting excretion and removing dirt, activating qi and excreting water, and strengthening healthy energy and descending the turbid, and can be used for changing the internal environment of a human body, fundamentally solving the symptoms such as loss of appetite, hypoesthesia, abepithymia, drowsiness, hypourocrinia, face and lower limb edema, anemia, skin ulcer and itches and the like caused by uraemia, enabling the urinary system, the digestive system, the nervous system, the cardiovascular system, the respiratory system and substance metabolism to recover the self-regulating functions, and finally realizing the complete treatment on uraemia.
Description
Technical field
The invention belongs to the field of Chinese medicines, a kind ofly specifically treat uremic Chinese medicine composition.
Background technology
From the current research of China, uremia is not a kind of independently disease, but the total clinical syndrome of the nephropathy in various late periods, is that chronic renal failure enters the syndrome that end occurred during the stage eventually some row clinical manifestations form; Chronic renal failure is called for short chronic kidney hypofunction, and chronic kidney hypofunction refers to that various nephropathys cause the gradual irreversibility of renal function to go down, until the clinical syndrome that the series of symptoms that afunction occurs and metabolism disorder form; In fact uremia refers to that human body can not produce urine by kidney, and the refuse that metabolism is produced and unnecessary moisture excrete, and the murder by poisoning producing.
Uremia's symptom clinically has that appetite disappears, insensitive, apathy, drowsiness, hypourocrinia, face and lower limbs edema, anemia, skin are burst itches, sometimes can toss about and feel uneasyly even there is epilepsy, uremia can slowly occur, long-term hidden and be not found; Also can in several days, occur, occur obvious uremic symptom; Also can be diversified, not necessarily all symptoms all show.
International nephropathy association, international kidney fund alliance determine that in 2006 be " world's kidney day " second Thursday in annual March, and this decision is intended to highlight the harm of kidney disease to the mankind, wakes the understanding of people to kidney and kidney disease up.
We show in national EPDML investigation, and in crowd, the sickness rate of chronic kidney disease reaches 13%, and rough calculation is got off, and nearly there is the patient of 100,000,000 chronic kidney disease in China, whole latter stage renal failure patient nearly 2,000,000.And with existing medical level and diagnosis and treatment ability, also cannot stop part patient finally to develop into renal failure in latter stage at end, the uremia that namely we often say.Once enter uremia's stage, just must rely on kidney replacement therapy, or use artificial machine except refuse in body, or change a healthy kidney by organ transplantation.China just can do 5,000 routine renal transplantations every year, and rough calculation nearly gets off to have 150 many cases to wait in patient only have a patient finally can accept renal transplantation.
Chinese medicine is thought multiple " turbid " gas in uremic patient body." turbid " refers to turbid damp more, respectfully in body falls not normally, gasifies not all right, and it is unfavorable certainly to show disrespect on, and three warmers are stopped up stagnant, retention of water-damp in the body and condense the pathogenic factor that weighing of the five internal organs.In broad terms, " turbid " is all paathogenic factors.
The forfeiture of uremic patient renal function is the unbalance sign of a kind of inside of human body environment.Garbage in body can not excrete smoothly by kidney, has caused accumulating of the interior oxious gas of body, and " amassing " is sick.
Human body is an entity interkniting, and the sharp increase that kidney " amasss " gas causes the obstruction of health meridians.In the traditional Chinese medical science, often say " general rule not bitterly, general rule not bitterly ", although human body has the ability of self-cleaning, the health of uremic patient has arrived non-medical treatment and can not place the stage of paying no attention to.
The treatment of Chinese medicine and Western medicine is at present a kind of more than method all, but effect is all not bery desirable.
Summary of the invention
The problem to be solved in the present invention is for above problem, provides the treatment that a kind of cure rate is high, relapse rate is low uremic Chinese medicine composition; This Chinese medicine composition adopts tcm theory, and uremic patient is treated and taken good care of, and has good therapeutic effect.
For addressing the above problem, the technical solution adopted in the present invention is:
Treat a uremic Chinese medicine composition, it is characterized in that, described Chinese medicine composition comprises the Chinese medicine of following weight portion:
Semen Pharbitidis 10-20 gram, Rhizoma Alismatis 10-20 gram, Os Draconis (calcined) 10-20 gram, Flos Sophorae Immaturus 10-20 gram, Radix Et Rhizoma Rhei 10-20 gram, Rhizoma Zingiberis Recens 10-20 gram, Herba Asari 5-10 gram, Radix Ginseng 10-20 gram, Semen Cuscutae 5-10 gram, Fructus Rosae Laevigatae 5-10 gram, Herba Epimedii 5-10 gram, Fructus Psoraleae 5-10 gram.
As a kind of prioritization scheme:
Described Chinese medicine composition comprises the Chinese medicine of following weight portion:
20 grams of Semen Pharbitidis, 15 grams of Rhizoma Alismatis, 20 grams of Os Draconis (calcined)s, 15 grams of the Flos Sophorae Immaturus, 20 grams of Radix Et Rhizoma Rhei, 10 grams, Rhizoma Zingiberis Recens, 5 grams of Herba Asaris, 10 grams of Radix Ginsengs, 5 grams of Semen Cuscutae, 10 grams of Fructus Rosae Laevigatae, 5 grams of Herba Epimedii, 5 grams of Fructus Psoraleaes.
As a kind of prioritization scheme:
Described Chinese medicine composition comprises the Chinese medicine of following weight portion:
20 grams of Semen Pharbitidis, 15 grams of Rhizoma Alismatis, 15 grams of Os Draconis (calcined)s, 15 grams of the Flos Sophorae Immaturus, 20 grams of Radix Et Rhizoma Rhei, 15 grams, Rhizoma Zingiberis Recens, 5 grams of Herba Asaris, 10 grams of Radix Ginsengs, 10 grams of Semen Cuscutae, 5 grams of Fructus Rosae Laevigatae, 5 grams of Herba Epimedii, 5 grams of Fructus Psoraleaes.
As a kind of prioritization scheme:
Described Chinese medicine composition comprises the Chinese medicine of following weight portion:
15 grams of Semen Pharbitidis, 20 grams of Rhizoma Alismatis, 20 grams of Os Draconis (calcined)s, 15 grams of the Flos Sophorae Immaturus, 15 grams of Radix Et Rhizoma Rhei, 10 grams, Rhizoma Zingiberis Recens, 5 grams of Herba Asaris, 10 grams of Radix Ginsengs, 5 grams of Semen Cuscutae, 10 grams of Fructus Rosae Laevigatae, 10 grams of Herba Epimedii, 5 grams of Fructus Psoraleaes.
Wherein: strengthening spleen, tonifying kidney, temperature compensation yang-energy, arrange turbid removing toxic substances, diarrhea dispel dirty, promoting the circulation of QI to induce diuresis, righting the turbid descending
Semen Pharbitidis has diuretic, relieving constipation, eliminates the phlegm, by effects such as drink, removing food stagnancy, parasite killing, return kidney, lung, large intestine, small intestine meridian, be mainly used to treat edema, ascites, beriberi, constipation, scrotal swelling, anal fistula inguinal bubo etc.In the present invention, Semen Pharbitidis can diarrhea be dispelled dirtyly, with this, treats uremia.
Rhizoma Alismatis is mainly used to the symptoms such as treatment is rushed down clearly kidney fire, emission due to deficiency of the kidney, diuretic, eliminating dampness by diuresis, expelled the heat-evil, dysuria, edema distending pain, vomiting, dysentery, beriberi, gonorrhea, hematuria, but Rhizoma Alismatis has liver toxicity, nephrotoxicity, take improper liver, the kidney of allowing and occur swelling and other poisoning symptom.Rhizoma Alismatis can promoting the circulation of QI to induce diuresis, and starts with to treat uremia with this.
Os Draconis (calcined) is a kind of famous and precious medical material, and, insomnia and dreamful sleep forgetful to treatment severe palpitation has good effect.Have that shock composes oneself, the effect of arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Os Draconis (calcined) can strengthening spleen, tonifying kidney, and temperature compensation yang-energy, has good curative effect for the protection of kidney and the recovery of renal function.
Flos Sophorae Immaturus cold nature, bitter in the mouth, has removing heat from blood, hemostasis, liver heat removing, pathogenic fire purging, has blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, haematemesis, liver-heat, conjunctival congestion.The effects such as headache is dizzy, can also reduce blood pressure.The Flos Sophorae Immaturus can be arranged turbid removing toxic substances, is beneficial to and discharges kidney portion toxin, recovers renal function.
Radix Et Rhizoma Rhei is mainly used in purging heat that poison, removing mass are stagnant, blood stasis expelling blood, excess-heat constipation, YANG jaundice, edema, etc. the treatment of symptom.Radix Et Rhizoma Rhei can be arranged turbid removing toxic substances, promoting the circulation of QI to induce diuresis, discharges kidney portion toxin, accelerates kidney portion blood circulation, so that normal function recovers in kidney portion.
Rhizoma Zingiberis Recens, except the flavoring agent as a kind of food in daily life, can also be used to treat oral ulcer, abundant expectoration cough, migraine, facial skin sore, periodontitis, drunk etc., and the traditional Chinese medical science thinks, Rhizoma Zingiberis Recens is hot thing, can temperature compensation yang-energy, discharge toxin.
Herba Asari cures mainly and dispels the wind, antipyretic, relieving asthma, cold expelling, Hang Shui, have one's ideas straightened out, air-cooled headache, phlegm retention cough with dyspnea etc.Carefully there is effect, antibacterial, the antiviral effect of maincenter inhibition and help raising organism metabolism.Herba Asari can righting dispels the wind, the turbid descending, is convenient to the recovery of renal function.
Radix Ginseng sweet in the mouth, micro-hardship, slightly warm in nature, return spleen, lung, the heart, kidney channel, there is the effects such as invigorating QI to relieve exhaustion, spleen invigorating lung benefiting, mind calming Fructus Alpiniae Oxyphyllae, nourishing blood to promote the production of body fluid, cure mainly serious disease, prolonged illness, lose blood, the vigour wish due to de-liquid is de-, sallow, the impotence due to deficiency of the kidney of Mental fatigue faint pulse, the empty hyperhidrosis of body, blood deficiency, frequent micturition, deficiency of vital energy diseases caused by exogenous pathogenic factor etc.Radix Ginseng can strengthening spleen, tonifying kidney, temperature compensation yang-energy, fundamentally cures kidney portion disease.
Semen Cuscutae has the effect of nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal, for impotence and seminal emission, dripping urination, the enuresis, frequent micturition, blurred vision tinnitus, suffer from a deficiency of the kidney, vaginal bleeding during pregnancy, spleen suffer from a deficiency of the kidney rush down, deficiency of the liver and kindey, spleen are suffered from a deficiency of the kidney damages, have tonifying YANG, regulate in external secretion, adjusting heart rate, blood pressure, delay the effects such as Cataractogenesis.
Fructus Rosae Laevigatae has reinforcing the kidney and controlling nocturnal emission, reducing urination and antidiarrheal, promoting blood circulation to remove blood stasis, expelling wind and removing dampness, removing toxic substances convergence, parasite killing and regulates the effect of urinary system, return kidney, bladder, large intestine, spleen, lung meridian, cure mainly the enuresis, seminal emission, frequency of micturition, insufficiency of the spleen dysentery, cough due to deficiency of the lung etc.
Herba Epimedii is returned liver, kidney channel, has the effect of the kidney invigorating, tonifying YANG, is mainly used to impotence due to deficiency of the kidney, seminal emission premature ejaculation, cold extremities with aversion to cold, expelling wind and removing dampness, diuresis etc.
Fructus Psoraleae can be used for the treatment of the diseases such as insufficiency of kidney-YANG, below element deficiency and cold, chills and pain of the waist and kness, frequent micturition, the enuresis, failure of the kidney in receiving QI, dyspnea due to deficiency are more than, asthenia of both the spleen and kidney, stool chronic diarrhea, but has toxicity, can not long-term taking.
Every taste Chinese medicine of the present invention is all by drawing after several clinical formulation, can make as required tablet, pill, the dosage forms such as powder, take rear drug main from spleen, stomach is through liver, kidney, there is strengthening spleen, tonifying kidney, temperature compensation yang-energy, arrange turbid removing toxic substances, diarrhea is dispelled dirty, promoting the circulation of QI to induce diuresis, the effect of righting the turbid descending, change the interior environment of human body, , fundamentally solving the appetite causing because of uremia disappears, insensitive, apathy, drowsiness, hypourocrinia, face and lower limbs edema, anemia, the skin symptom such as itch of bursting, make urinary system, digestive system, nervous system, cardiovascular system, respiratory system and substance metabolism recover the function of self regulation, finally realize uremic thorough treatment.
While taking, the water decoction of said medicine, also can make tablet, powder, etc. take.
Instructions of taking: every day potion, every natural gift three times, bfore meals, within ten days, be a course for the treatment of.
The present invention is according to the pharmacology of above-mentioned Chinese medicine, and clinical trial for several times, to blue or green, in, old all ages and classes section gently, in, severe uremic patient, and appetite disappears, insensitive, apathy, drowsiness, hypourocrinia, face and lower limbs edema, anemia, skin are burst itches, sometimes can toss about and feel uneasyly even there is epilepsy, uremia can slowly occur, long-term hidden and be not found; Also can in several days, occur, occur that the dissimilar patients such as obvious uremic symptom all have obvious therapeutic effect.
In order better to investigate clinical efficacy and the safety of medicine of the present invention, we have selected, and 200 examples are slight, moderate, severe uremic patient have been carried out clinical trial with the therapeutic effect of medicine of the present invention.
200 routine patients are divided into two groups at random, every group of 100 people, matched group male 60 examples, women's 40 examples, age 20-35 year 20 examples.36-50 year 35 examples.51 years old 45 above examples; Treatment group, male's 63 examples, women's 37 examples, age 20-35 year 25 examples, 36-50 year 35 examples, 51 years old 40 above example; Sick time one to two year.
Two groups of cases are Epidemiological Analysis by statistics at aspects such as sex, age, the courses of disease, has comparability.
Matched group adopts current general Therapeutic Method, does kidney dialysis, and treatment group is taken the water decoction of medicine of the present invention, potion on the one, and potion divides to be taken for three times, and treatment time is 30 days.
Treatment standard: appetite disappears, insensitive, apathy, drowsiness, hypourocrinia, face and lower limbs edema, anemia, skin are burst itches, and sometimes can toss about and feel uneasyly even occur epilepsy, and uremia can slowly occur, long-term hidden and be not found; Also can be several
Cure---sign is normal, diet is normal, sleep is normal, emotion is normal:
Effective---sign normally, once in a while with insensitive, drowsiness, diet is normal
Effectively---urine amount less, drowsiness, apathy, diet is normal;
Invalid---inappetence, insensitive, apathy, drowsiness, urine amount is few;
Table one
| Group | Number of cases | Cure n (%) | Effective n (%) | Effective n (%) | Invalid n (%) | Total effective rate n (%) |
| Matched group | 100 | 60(40.0) | 80(80.0) | 86(86.0) | 14(14.0) | 86(86.0) |
| Treatment group | 100 | 92(92.0) | 97(97.0) | 98(99.0) | 1(1.00) | 99(99.0) |
By the contrast in above-mentioned table one, not only cost is low can to find out Chinese medicine composition of the present invention, and cure rate is high, therapeutic effect is remarkable, compares with doing kidney dialysis, and not only total effective rate is dialysed higher than kidney, and treating both the principal and secondary aspects of a disease, can fundamentally cure uremia, and good stability is difficult for recurrence.
The specific embodiment
Embodiment 1: a kind ofly treat uremic Chinese medicine composition, described medicine is comprised of 5 grams of 20 grams of Semen Pharbitidis, 15 grams of Rhizoma Alismatis, 20 grams of Os Draconis (calcined)s, 15 grams of the Flos Sophorae Immaturus, 20 grams of Radix Et Rhizoma Rhei, 10 grams, Rhizoma Zingiberis Recens, 5 grams of Herba Asaris, 10 grams of Radix Ginsengs, 5 grams of Semen Cuscutae, 10 grams of Fructus Rosae Laevigatae, 5 grams of Herba Epimedii, Fructus Psoraleae.
After said medicine raw material is mixed, add water and decoct half an hour, elimination medicinal residues, just oral water decoction, every day potion, every bu is taken for three times, bfore meals, within ten days, is a course for the treatment of, just can fully recover three to four courses for the treatment of, can follow the doctor's advice and require dose to carry out suitable increase or minimizing, during taking, avoid pungently, avoid greasy.
Embodiment 2: a kind ofly treat uremic Chinese medicine composition, described medicine is comprised of 5 grams of 20 grams of Semen Pharbitidis, 15 grams of Rhizoma Alismatis, 15 grams of Os Draconis (calcined)s, 15 grams of the Flos Sophorae Immaturus, 20 grams of Radix Et Rhizoma Rhei, 15 grams, Rhizoma Zingiberis Recens, 5 grams of Herba Asaris, 10 grams of Radix Ginsengs, 10 grams of Semen Cuscutae, 5 grams of Fructus Rosae Laevigatae, 5 grams of Herba Epimedii, Fructus Psoraleae.
After said medicine raw material is mixed, add water and decoct half an hour, elimination medicinal residues, just oral water decoction, every day potion, every bu is taken for three times, bfore meals, within ten days, is a course for the treatment of, just can fully recover three to four courses for the treatment of, can cup doctor's advice require dose carry out suitable increase or minimizing, during taking, avoid pungently, avoid greasy.
Embodiment 3: a kind ofly treat uremic Chinese medicine composition, described medicine is comprised of 5 grams of 15 grams of Semen Pharbitidis, 20 grams of Rhizoma Alismatis, 20 grams of Os Draconis (calcined)s, 15 grams of the Flos Sophorae Immaturus, 15 grams of Radix Et Rhizoma Rhei, 10 grams, Rhizoma Zingiberis Recens, 5 grams of Herba Asaris, 10 grams of Radix Ginsengs, 5 grams of Semen Cuscutae, 10 grams of Fructus Rosae Laevigatae, 10 grams of Herba Epimedii, Fructus Psoraleae.
After said medicine raw material is mixed, add water and decoct half an hour, elimination medicinal residues, just oral water decoction, every day potion, every bu is taken for three times, bfore meals, within ten days, is a course for the treatment of, just can fully recover three to four courses for the treatment of, can cup doctor's advice require dose carry out suitable increase or minimizing, during taking, avoid pungently, avoid greasy.
Part successful case:
Pan XX, female, 52 years old, the cough that once common flu causes, was developed into and was said that three or five will hurriedly be coughed by slight dry cough afterwards, and this is coughed and has unexpectedly coughed 20 years.Except cough is also with nauseating, vomiting, weak, Mild edema.In hospital's routine that has urine examined, show, occult blood (3+), then the routine of having a blood test, serum creatinine has reached 580umol/L, and she has suffered from uremia.She accepts dialysis doctor advised.Take a course for the treatment of after the present invention, symptom has obvious change, takes after three courses for the treatment of, and diet, daily life recover normal, recurrence.
Lee XX, man, 59 years old, suffer from uremia 2 years, take Western medicine, but effect is bad always, take four courses for the treatment of after benzene invention, hydrouria, diet is normal, and other symptoms also disappear substantially, fully recover after taking continuously two courses for the treatment of.
Lu XX, man, 48 years old, suffer from uremia 3 years, three courses for the treatment of of kidney dialysis, there is no remarkable improvement, insensitive, apathy, drowsiness, to take after two courses for the treatment of of the present invention, defecation is normal, and appetite is good, continues to take after four courses for the treatment of, cures without recurrence.
Claims (4)
1. the uremic Chinese medicine composition for the treatment of, is characterized in that, described Chinese medicine composition comprises the Chinese medicine of following weight portion:
Semen Pharbitidis 10-20 gram, Rhizoma Alismatis 10-20 gram, Os Draconis (calcined) 10-20 gram, Flos Sophorae Immaturus 10-20 gram, Radix Et Rhizoma Rhei 10-20 gram, Rhizoma Zingiberis Recens 10-20 gram, Herba Asari 5-10 gram, Radix Ginseng 10-20 gram, Semen Cuscutae 5-10 gram, Fructus Rosae Laevigatae 5-10 gram, Herba Epimedii 5-10 gram, Fructus Psoraleae 5-10 gram.
2. Chinese medicine composition according to claim 1, is characterized in that: described Chinese medicine composition comprises the Chinese medicine of following weight portion:
20 grams of Semen Pharbitidis, 15 grams of Rhizoma Alismatis, 20 grams of Os Draconis (calcined)s, 15 grams of the Flos Sophorae Immaturus, 20 grams of Radix Et Rhizoma Rhei, 10 grams, Rhizoma Zingiberis Recens, 5 grams of Herba Asaris, 10 grams of Radix Ginsengs, 5 grams of Semen Cuscutae, 10 grams of Fructus Rosae Laevigatae, 5 grams of Herba Epimedii, 5 grams of Fructus Psoraleaes.
3. Chinese medicine composition according to claim 1, is characterized in that: described Chinese medicine composition comprises the Chinese medicine of following weight portion:
20 grams of Semen Pharbitidis, 15 grams of Rhizoma Alismatis, 15 grams of Os Draconis (calcined)s, 15 grams of the Flos Sophorae Immaturus, 20 grams of Radix Et Rhizoma Rhei, 15 grams, Rhizoma Zingiberis Recens, 5 grams of Herba Asaris, 10 grams of Radix Ginsengs, 10 grams of Semen Cuscutae, 5 grams of Fructus Rosae Laevigatae, 5 grams of Herba Epimedii, 5 grams of Fructus Psoraleaes.
4. Chinese medicine composition according to claim 1, is characterized in that: described Chinese medicine composition comprises the Chinese medicine of following weight portion:
15 grams of Semen Pharbitidis, 20 grams of Rhizoma Alismatis, 20 grams of Os Draconis (calcined)s, 15 grams of the Flos Sophorae Immaturus, 15 grams of Radix Et Rhizoma Rhei, 10 grams, Rhizoma Zingiberis Recens, 5 grams of Herba Asaris, 10 grams of Radix Ginsengs, 5 grams of Semen Cuscutae, 10 grams of Fructus Rosae Laevigatae, 10 grams of Herba Epimedii, 5 grams of Fructus Psoraleaes.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105055964A (en) * | 2015-08-27 | 2015-11-18 | 殷永洲 | Traditional Chinese medicine composition for treating uremia |
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| JPS60142258A (en) * | 1983-12-29 | 1985-07-27 | Inahata Sangyo Kk | Reagent for diagnosis of iga kidney disease |
| CN101897942A (en) * | 2009-05-31 | 2010-12-01 | 北京四环科宝制药有限公司 | Method for detecting medicine composition for warming spleen and tonifying kidney and releasing turbidity and eliminating stasis |
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| CN105055964A (en) * | 2015-08-27 | 2015-11-18 | 殷永洲 | Traditional Chinese medicine composition for treating uremia |
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