CN104857107A - Fat-reducing composition preparation method and fat-reducing agent - Google Patents
Fat-reducing composition preparation method and fat-reducing agent Download PDFInfo
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a preparation method of a fat-reducing composition. The preparation method comprises the steps of preparing a first component and a second component, wherein the first component comprises the following substances in percentage by weight accounting for the total weight of the first component and the second component: 8% to 10% of red flower, 15% to 30% of myrrh, 4% to 6% of radix angelicae pubescentis, 3% to 5% of selfheal, 3% to 5% of hawthorn, 5% to 8% of frankincense, 5% to 7% of garcinia pedunculata, 2% to 3% of semen brassicae, 3% to 4% of seaweed and 2% to 5% of mint, and the second component comprises the following substances in percentage by weight accounting for the total weight of the first component and the second component: 1% to 2% of azone, 0.2% to 3% of borneol, 4% to 6% of 1,3-butanediol, 1% to 3% of glycerol, 0.1% to 0.5% of Carbomer, 0.1% to 0.5% of sodium hydroxide, 2% to 5% of ethyl alcohol, 0.2% to 0.8% of phenoxyethanol and the balance of deionized water; then mixing the first component with the second component uniformly after decocting, concentrating, separating and sterilizing the first component. The fat-reducing composition obtained by the preparation method has an obvious weight-reducing effect.
Description
Technical field
The present invention relates to a kind of compositions with fat reducing function, particularly relate to the preparation method of said composition.
Background technology
Simple Obesity refers to the obesity caused primarily of inherited genetic factors and overnutrition, Simple Obesity is modal one in all kinds of obesity, account for about 95% of obese people, the people's total body fat distribution suffering from Simple Obesity is more even, there is no endocrine regulation phenomenon, also without dysbolismus disease, often there is fat medical history in its family.
At present, Simple Obesity is a social problem of the highly developed country of modern economy.At some national obesity sickness rate up to 20 ~ 30%.China is due to social stability, and people's living standard improves, and dietary structure and custom are reasonable not in addition, and Simple Obesity sickness rate is also in rising trend.According to China in recent years, neonate accounted for 70%, and child 4 ~ 9.5%, adolescence 21%, the manhood 18 ~ 32%, and the geratic period reaches 28% and all suffers from obesity, but its effect of existing diet products is often obvious not.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind ofly to be had the fat reducing compositions of remarkable fat-reducing effect and provides a kind of fitness reducing agent using this fat reducing compositions to prepare.
For solving the problems of the technologies described above, the present invention adopts following technical scheme:
A preparation method for fat reducing compositions, comprises the steps:
1) configure the first component and second component, the percentage ratio that each material wherein forming the first component accounts for first, second component weight is: Flos Carthami 8-10%; Myrrha 15-30%; Radix Angelicae Pubescentis 4-6%; Spica Prunellae 3-5%; Fructus Crataegi 3-5%; Olibanum 5-8%; Large fruit Resina garciniae 5-7%; Semen Sinapis Albae 2-3%; Sargassum 3-4%; Herba Menthae 2-5%; The percentage ratio that each material of composition second component accounts for first, second component weight is: azone 1-2%; Borneolum Syntheticum 0.2-3%; 1.3 butanediol 4-6%; Glycerol 1-3%; Carbomer 0.1-0.5%; Sodium hydroxide 0.1-0.5%; Ethanol 1-5%; Phenoxyethanol 0.2-0.8%; Surplus is deionized water;
2) the first component is decocted with water, get its medicinal liquid, for subsequent use after concentrated, separation, sterilizing;
3) by second component mix homogeneously, and the first component is added second component and to stir obtained fat reducing compositions.
In formula of the present invention:
Flos Carthami, Classification system: Carthamustinctorius L., another name: red indigo plant flower, thorn Flos Carthami, Compositae, Flos Carthami platymiscium, have blood circulation promoting and blood stasis dispelling, and wet dissipation goes the effect swollen.
Myrrha, has another name called myrrh, cures mainly breast abdomen stasis of blood pain, dysmenorrhea, amenorrhea, lump in the abdomen, traumatic injury, carbuncle skin infection, acute appendicitis, conjunctival congestion and swelling pain, has the effect such as promoting blood circulation and stopping pain, detumescence and promoting granulation.
Radix Angelicae Pubescentis, another name Sempervivum tectorum, solely cunning, archangel, has expelling wind and removing dampness, arthralgia aggravated by cold analgesic efficacy.
Spica Prunellae, formal name used at school: Prunella vulgaris L, another name: wheat head Spica Prunellae, can control conjunctival congestion and swelling pain, headache etc., clearing away heat-fire, improving eyesight, mass dissipating and swelling eliminating.
Fructus Crataegi, (Crataeguspinnatifida Bunge), to have another name called in mountain fruit, Rosaceae Crataegus, has aid digestion, blood fat reducing, antiatherogenic effect.
Olibanum, Boswellia, has blood-activating and qi-promoting pain relieving, effect of detumescence and promoting granulation.Be usually used in treating obstruction of qi in the chest and cardialgia, gastralgia, dysmenorrhea amenorrhea, postpartum stagnation, lump in the abdomen is suffered from abdominal pain, rheumatic arthralgia, the contracture of muscle arteries and veins, traumatic injury, carbuncle skin infection etc.
Large fruit Resina garciniae (Garciniapedunculata Roxb.), has another name called weight reducing fruit, fat-reducing fruit, has weight reducing, strengthening the spleen to promote digestion, the effects such as loosening bowel to relieve constipation, relieving sore throat and diminishing swelling, extra-nutrition, cancer-resisting.
Semen Sinapis Albae, another name hot food, Latin literary fame Semen sinapis. has warming the lung eliminating phlegm promoting the circulation of QI, resolving mass and removing the obstruction of the collateral analgesic efficacy.
Sargassum nature and flavor are salty-cold, have effect of heat clearing away, hard masses softening and resolving.
Herba Menthae is pungent cool property sweating antipyretic medicine, the disease such as be usually used in treatment influenza, headache, conjunctival congestion, fever of the body, throat, dental bed swell and ache.
Azone, molecular formula C18H35NO, can be used as penetrating agent,
Borneolum Syntheticum, has another name called Fructus Citri tangerinae sheet, is through steam distillation and recrystallization and obtaining by Compositae Herba Blumeae Balsamiferae stem and leaf or canella Borneolum Syntheticum Camphor tree branch and leaf.Can be used for treatment excess syndrome of stroke coma, conjunctival congestion and swelling pain, sore throat aphtha, to swell and ache for skin infection, do not hold back after bursting.
Carbomer, English name Carbomer is the high molecular polymer of acrylic acid bonding allyl sucrose or tetramethylolmethane allyl ether.
The main pharmacological of this formula is the activity of reconditioner body fat and metabolic enzyme, promotes that body fat is decomposed, makes body be issued to the object of fat-reducing at normal physiological condition.
Preferably, step 2) mass ratio of the first component and water is 1:4-6, decocts 1 to 3 time, merges each medicinal liquid decocted.
Preferably, decoct 3 times to the first component, the water yield of wherein first time decoction is 6 times of the first component, and the water yield of second and third decoction is 4 times.More specifically, before first time decocts, invade bubble 4-6 hour, decoct boiling and continue 30 minutes.
Preferably, the present invention first component crosses 60 mesh sieves.
Preferably, step 2) adopt thin film concentration by concentration of liquid medicine to 0.5-0.9g/ml.Concrete, add the ethanol with medicinal liquid identical weight in concentration of liquid medicine forward direction medicinal liquid, through its medicinal liquid of leaching after sedimentation.
Step 2 of the present invention) adopt centrifugalize, rotating speed is 3000 revs/min, and centrifugation time is 30 minutes.
Step 2 of the present invention) sterilising temp is 105 DEG C, sterilization time is 30 minutes.
Present invention also offers a kind of fitness reducing agent with fat reducing effect, be made up of above-mentioned gained fat reducing compositions and Transparent soap base, the mass ratio of wherein fat reducing compositions and Transparent soap base is 20:80.
The present invention takes full advantage of the advantageous natural resources of Chinese medicinal materials of China, and from over one hundred kind of Chinese herbal medicine, filter out the ten multi-flavor Chinese medicines such as Flos Carthami, Myrrha, Radix Angelicae Pubescentis, Fructus Crataegi, the extraction process through strict scientific composition and uniqueness extracts fat reducing compositions.Due to this effective ingredient and the soap class as carrier, be natural materials completely, transdermal stimulation is tested, and does not produce any irritative response to human body skin.
Confirmed by modern medical research methods, the main pharmacological of this formula is the activity of reconditioner body fat and metabolic enzyme, promote that body fat is decomposed, body is made to be issued to the object of fat-reducing at normal physiological condition, this anti-obesity mechanism than using appetite inhibiting class medicine, lead let out class medicine, hormone medicine fat-reducing is more conducive to health, achieve fat-reducing and do not force the beneficial effect of going on a diet, not subtracting muscle power, not causing metabolism disorder.
Detailed description of the invention
Below by embodiment, the present invention is specifically described further.Simple the substituting of design philosophy of the present invention or allied substances belongs to protection scope of the present invention.If following used experimental technique is without specified otherwise, be the method for the existing routine of the art, the batching used or material, if no special instructions, be by the available batching of commercial sources or material.
Embodiment 1
Fitness reducing agent of the present invention is prepared by following steps:
1) configure the first component and second component, the percentage ratio that each material wherein forming the first component accounts for first, second component weight is: Flos Carthami 7%; Myrrha 20%; Radix Angelicae Pubescentis 6%; Spica Prunellae 5%; Fructus Crataegi 4%; Olibanum 5%; Large fruit Resina garciniae 7%; Semen Sinapis Albae 3%; Sargassum 4%; Herba Menthae 5%;
The percentage ratio that each material of composition second component accounts for first, second component weight is: azone 2%; Borneolum Syntheticum 0.2%; 1.3 butanediols 4%; Glycerol 3%; Carbomer 0.1% (production of Hubei Kang Baotai fine chemistry industry company); Sodium hydroxide 0.1%; Ethanol 2%; Phenoxyethanol 0.2%; Surplus is deionized water;
2) the first component is proceeded as follows:
Pretreatment
The Chinese medicine of the first component is prepared in proportion, crosses 60 mesh sieves, remove earth;
Decoct
The Chinese medicine of the first component is put into storage tank, soaks 4-6 hours, the mass ratio of the first component drug quality and water is 1:6, then decocts to boiling at ambient pressure, and keeps boiling 30 minutes, and last vertical centrifugal goes out the medicinal liquid of first time decoction.
After taking out medicinal liquid, the water adding the first component drug quality 4 times again in medicine carries out second time and decocts, centrifugal go out second time medicinal liquid, equally, the water adding the first component drug quality 4 times again in medicine carries out third time decoction, centrifugal go out third time medicinal liquid, by above three times decoct medicinal liquid combine.
Concentrate and precipitate with ethanol
By above-mentioned medicine liquid thin film concentration traditionally, (thin film concentration refers to a kind of concentrating under reduced pressure mode of carrying out with membrane evaporator, prior art, the present invention is not described in detail) mode is concentrated into 0.5-0.6g crude drug/ml, and after taking out, normal pressure is concentrated into 0.9g crude drug/ml; Cooling sedimentation, places 1 hour by medicinal liquid room temperature, until equilibrium at room temperature; Add the ethanol with medicinal liquid 1:1, stir evenly rear sedimentation 1 hour, filtering precipitate is to clear liquid, and thin film concentration is to 0.9g crude drug/ml;
Be separated
By the medicinal liquid centrifugalize after concentrated, centrifugal rotational speed is 3000 revs/min, and centrifugation time is 30 minutes; Incline and supernatant, load sterilizing in sterilizing bottle, sterilising temp is 105 DEG C, and sterilization time is 30 minutes.
3) second component is fully dissolved, mix homogeneously, and the first component is added second component and to stir obtained fat reducing compositions.
4) by step 3) gained fat reducing compositions pour into Transparent soap base (Ba Sha cosmetics of everyday use company limited of Shenzhen produce, model is 1008) in, stir, pour into fat-reducing fancy soap, the mass ratio of fat reducing compositions and Transparent soap base is 20:80.
The using method of the present embodiment gained fat-reducing fancy soap: use the same wiping health of general fancy soap at shower time image.
Through toxotest, rat is divided three dosage groups oral 4 months, to the discovery all without exception of its body weight, food-intake, liver function, renal function, blood, routine urinalysis and each tissue pathology checking.
Salmonella reversion test and CHL cell tests system results show all not present mutagenicity.
Test 1 fat-reducing effect
This experiment carries out questionnaire survey for simple obesity patient, in the patient using embodiment 1 gained fitness reducing agent, random choose 100 uses the user of the present embodiment fat-reducing soap surrounding to investigate for more than 16 years old, statistical result is as shown in table 1, fat-reducing effect is divided into Three Estate by this experiment, it is effective, effective respectively and minor effect, as can be seen from Table 1, the present embodiment fitness reducing agent all has remarkable result on the fat-reducing effect of body weight, abdominal circumference and hip circumference, especially can obviously reduce abdominal circumference size.
Table 1 experimenter fat-reducing effect statistical table
Experiment 2
This experiment carries out questionnaire survey for simple obesity patient, in the patient using embodiment 1 gained fitness reducing agent, random choose 20 uses the user of surrounding to investigate for 8 ~ 14 years old, statistical result is as shown in table 2 to table 4, result shows, the present embodiment fitness reducing agent has significant fat-reducing effect equally to teenager.
The test result of table 2 pair teenager body weight
The test result of table 3 pair teenager abdominal circumference
The test result of table 4 pair teenager hip circumference
Embodiment 2
Fitness reducing agent of the present invention is prepared by following steps:
1) configure the first component and second component, the percentage ratio that each material wherein forming the first component accounts for first, second component weight is: Flos Carthami 10%; Myrrha 30%; Radix Angelicae Pubescentis 6%; Spica Prunellae 5%; Fructus Crataegi 5%; Olibanum 5%; Large fruit Resina garciniae 5%; Semen Sinapis Albae 2%; Sargassum 3%; Herba Menthae 3%;
The percentage ratio that each material of composition second component accounts for first, second component weight is: azone 1%; Borneolum Syntheticum 3%; 1.3 butanediols 6%; Glycerol 1%; Carbomer 0.5%; Sodium hydroxide 0.5%; Ethanol 5%; Phenoxyethanol 0.8%; Surplus is deionized water;
2) the first component is proceeded as follows:
Pretreatment
The Chinese medicine of the first component is prepared in proportion, crosses 60 mesh sieves, remove earth;
Decoct
The Chinese medicine of the first component is put into storage tank, soaks 4-6 hours, the mass ratio of the first component drug quality and water is 1:6, then decocts to boiling at ambient pressure, and keeps boiling 30 minutes, and last vertical centrifugal goes out the medicinal liquid of first time decoction.
After taking out medicinal liquid, the water adding the first component drug quality 4 times again in medicine carries out second time and decocts, centrifugal go out second time medicinal liquid, equally, the water adding the first component drug quality 4 times again in medicine carries out third time decoction, centrifugal go out third time medicinal liquid, by above three times decoct medicinal liquid combine.
Concentrated
By above-mentioned medicinal liquid thin film concentration to 0.5-0.6g crude drug/ml, after taking out, normal pressure is concentrated into 0.9g crude drug/ml; Cooling sedimentation, places 1 hour by medicinal liquid room temperature, until equilibrium at room temperature; Add the ethanol with medicinal liquid 1:1, stir evenly rear sedimentation 1 hour, filtering precipitate is to clear liquid, and thin film concentration is to 0.9g crude drug/ml;
Be separated
By the medicinal liquid centrifugalize after concentrated, centrifugal rotational speed is 3000 revs/min, and centrifugation time is 30 minutes; Incline and supernatant, load sterilizing in sterilizing bottle, sterilising temp is 105 DEG C, and sterilization time is 30 minutes.
3) by second component mix homogeneously, and the first component is added second component and to stir obtained fitness reducing agent.
The present embodiment anoretic is actually a kind of fat-reducing ointment frost, can spread upon on skin and use by Direct Uniform.
Through toxotest, rat is divided three dosage groups oral 4 months, to the discovery all without exception of its body weight, food-intake, liver function, renal function, blood, routine urinalysis and each tissue pathology checking.
Salmonella reversion test and CHL cell tests system results show all not present mutagenicity.
Experiment 3
This experiment carries out questionnaire survey for simple obesity patient, in the patient using embodiment 1 gained fitness reducing agent, random choose 100 uses the user of surrounding to investigate for more than 16 years old, statistical result is as shown in table 5, fat-reducing effect is divided into Three Estate by this experiment, is effective, effective respectively and minor effect.As can be seen from Table 5, the present embodiment fitness reducing agent all has remarkable result on the fat-reducing effect of body weight, abdominal circumference and hip circumference, especially can obviously reduce abdominal circumference size.
Table 5 experimenter fat-reducing effect statistical table
Experiment 4
This experiment carries out questionnaire survey for simple obesity patient, in the patient using embodiment 1 gained fitness reducing agent, random choose 20 uses the user of surrounding to investigate for 8 ~ 14 years old, statistical result is as shown in table 6 to table 8, result shows, the present embodiment fitness reducing agent has significant fat-reducing effect equally to teenager.
The test result of table 6 pair teenager body weight
The test result of table 7 pair teenager abdominal circumference
The test result of table 8 pair teenager hip circumference
Embodiment 3
Fitness reducing agent of the present invention is prepared by following steps:
1) configure the first component and second component, the percentage ratio that each material wherein forming the first component accounts for first, second component weight is: Flos Carthami 8%; Myrrha 15%; Radix Angelicae Pubescentis 4%; Spica Prunellae 3%; Fructus Crataegi 3%; Olibanum 8%; Large fruit Resina garciniae 5%; Semen Sinapis Albae 2%; Sargassum 3%; Herba Menthae 2%;
The percentage ratio that each material of composition second component accounts for first, second component weight is: azone 1%; Borneolum Syntheticum 3%; 1.3 butanediols 6%; Glycerol 1%; Carbomer 0.5%; Sodium hydroxide 0.5%; Ethanol 5%; Phenoxyethanol 0.8%; Surplus is deionized water;
2) the first component is proceeded as follows:
Pretreatment
The Chinese medicine of the first component is prepared in proportion, crosses 60 mesh sieves, remove earth;
Decoct
The Chinese medicine of the first component is put into storage tank, soaks 4-6 hours, the mass ratio of the first component drug quality and water is 1:6, then decocts to boiling at ambient pressure, and keeps boiling 30 minutes, and last vertical centrifugal goes out the medicinal liquid of first time decoction.
After taking out medicinal liquid, the water adding the first component drug quality 4 times again in medicine carries out second time and decocts, centrifugal go out second time medicinal liquid, equally, the water adding the first component drug quality 4 times again in medicine carries out third time decoction, centrifugal go out third time medicinal liquid, by above three times decoct medicinal liquid combine.
Concentrated
By above-mentioned medicinal liquid thin film concentration to 0.5-0.6g crude drug/ml, after taking out, normal pressure is concentrated into 0.9g crude drug/ml; Cooling sedimentation, places 1 hour by medicinal liquid room temperature, until equilibrium at room temperature; Add the ethanol with medicinal liquid 1:1, stir evenly rear sedimentation 1 hour, filtering precipitate is to clear liquid, and thin film concentration is to 0.9g crude drug/ml;
Be separated
By the medicinal liquid centrifugalize after concentrated, centrifugal rotational speed is 3000 revs/min, and centrifugation time is 30 minutes; Incline and supernatant, load sterilizing in sterilizing bottle, sterilising temp is 105 DEG C, and sterilization time is 30 minutes.
3) by second component mix homogeneously, and the first component is added second component and to stir obtained fitness reducing agent.
4) by step 3) gained fat reducing compositions pours in Transparent soap base, and stir, pour into fat-reducing fancy soap, the mass ratio of fat reducing compositions and Transparent soap base is 5:95.
Through toxotest, rat is divided three dosage groups oral 4 months, to the discovery all without exception of its body weight, food-intake, liver function, renal function, blood, routine urinalysis and each tissue pathology checking.
Salmonella reversion test and CHL cell tests system results show all not present mutagenicity.
Experiment 5
This experiment carries out questionnaire survey for simple obesity patient, in the patient using embodiment 1 gained fitness reducing agent, random choose 100 uses the user of surrounding to investigate for more than 16 years old, statistical result is as shown in table 9, fat-reducing effect is divided into Three Estate by this experiment, is effective, effective respectively and minor effect.As can be seen from Table 9, the present embodiment fitness reducing agent all has remarkable result on the fat-reducing effect of body weight, abdominal circumference and hip circumference, especially can obviously reduce abdominal circumference size.
Table 9 experimenter fat-reducing effect statistical table
Experiment 6
This experiment carries out questionnaire survey for simple obesity patient, in the patient using embodiment 1 gained fitness reducing agent, random choose 20 uses the user of surrounding to investigate for 8 ~ 14 years old, statistical result is as shown in table 10 to table 12, result shows, the present embodiment fitness reducing agent has significant fat-reducing effect equally to teenager.
The test result of table 10 pair teenager body weight
The test result of table 11 pair teenager abdominal circumference
The test result of table 12 pair teenager hip circumference
Claims (10)
1. a preparation method for fat reducing compositions, comprises the steps:
1) configure the first component and second component, the percentage ratio that each material wherein forming the first component accounts for first, second component weight is: Flos Carthami 8-10%; Myrrha 15-30%; Radix Angelicae Pubescentis 4-6%; Spica Prunellae 3-5%; Fructus Crataegi 3-5%; Olibanum 5-8%; Large fruit Resina garciniae 5-7%; Semen Sinapis Albae 2-3%; Sargassum 3-4%; Herba Menthae 2-5%; The percentage ratio that each material of composition second component accounts for first, second component weight is: azone 1-2%; Borneolum Syntheticum 0.2-3%; 1.3 butanediol 4-6%; Glycerol 1-3%; Carbomer 0.1-0.5%; Sodium hydroxide 0.1-0.5%; Ethanol 2-5%; Phenoxyethanol 0.2-0.8%; Surplus is deionized water;
2) the first component is decocted with water, get its medicinal liquid, for subsequent use after concentrated, separation, sterilizing;
3) by second component mix homogeneously, and the first component is added second component and to stir obtained fat reducing compositions.
2. fat reducing preparation method of composition according to claim 1, is characterized in that, step 2) mass ratio of the first component and water is 1:4-6, decocts 1 to 3 time, merges each medicinal liquid decocted.
3. fat reducing preparation method of composition according to claim 2, is characterized in that, decocts 3 times to the first component, and the water yield of wherein first time decoction is 6 times of the first component, and the water yield of second and third decoction is 4 times.
4. fat reducing preparation method of composition according to claim 3, is characterized in that, invades bubble 4-6 hour before first time decocts, and decocts boiling and continues 30 minutes.
5. fat reducing preparation method of composition according to claim 4, is characterized in that, the first component crosses 60 mesh sieves.
6., according to the arbitrary described fat reducing preparation method of composition of claim 1 to 5, it is characterized in that, step 2) adopt thin film concentration by concentration of liquid medicine to 0.5-0.9g/ml.
7. fat reducing preparation method of composition according to claim 6, is characterized in that, adds the ethanol with medicinal liquid identical weight in concentration of liquid medicine forward direction medicinal liquid, through its medicinal liquid of leaching after sedimentation.
8. fat reducing preparation method of composition according to claim 7, is characterized in that, step 2) adopt centrifugalize, rotating speed is 3000 revs/min, and centrifugation time is 30 minutes.
9. fat reducing preparation method of composition according to claim 6, is characterized in that, step 2) sterilising temp is 105 DEG C, sterilization time is 30 minutes.
10. a fitness reducing agent, is made up of claim 1 to 9 gained fat reducing compositions and Transparent soap base, and the mass ratio of wherein fat reducing compositions and Transparent soap base is 5 ~ 20:80 ~ 95.
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CN105231199A (en) * | 2015-09-16 | 2016-01-13 | 安徽阜南常晖食品有限公司 | Fat eliminating and health preserving sweet orange drink |
CN105265948A (en) * | 2015-09-14 | 2016-01-27 | 安徽阜南常晖食品有限公司 | Immunity enhancing jelly coconut juice |
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CN1824194A (en) * | 2005-12-28 | 2006-08-30 | 王燕红 | Pure Chinese medicine external use body fat reducing medicine |
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CN1824194A (en) * | 2005-12-28 | 2006-08-30 | 王燕红 | Pure Chinese medicine external use body fat reducing medicine |
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CN105265948A (en) * | 2015-09-14 | 2016-01-27 | 安徽阜南常晖食品有限公司 | Immunity enhancing jelly coconut juice |
CN105231199A (en) * | 2015-09-16 | 2016-01-13 | 安徽阜南常晖食品有限公司 | Fat eliminating and health preserving sweet orange drink |
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