A kind of composition for treating bacillary intestinal inflammatory
Technical field:
The present invention relates to Chinese medicine and processing technique of Chinese herbs field, more particularly to a kind of combination for treating bacillary intestinal inflammatory
Thing.
Background technology:
Bacillary intestinal inflammatory is enteritis and colitis caused by bacterium, virus, fungi and parasite etc..Clinical manifestation
Mainly there are abdominal pain, diarrhea, dilute water just or mucus pus and blood stool.Some patients can have fever and tenesmus sensation, therefore also known as infect
Property diarrhea.Enteritis is different by course of disease length, is divided into acute and chronic two class.The chronic enteritis course of disease is faced generally more than two months
Bed common are chronic bacillary dysentery, chronic amebic dysentery, snail fever, nonspecific ulcerative colitis and limit office property
Enteritis etc..
With diagnostic method and medical advance, habits and customs and the change of dietary structure, its incidence also constantly rise, disease
Journey is again long, it is difficult to effects a radical cure, recurrent exerbation, it is touching refractory, and the health and quality of life of people is drastically influence, and canceration is sent out
Sick rate is classified as one of modern difficult treatment up to 5% or so, by the World Health Organization, although at present for enteritis treatment medicine not yet
It is few, but most drug effect measurements do not effect a permanent cure, and recurrence rate can also effectively effect a radical cure above-mentioned disease up to more than 85% without a kind of specific medicament
Disease.
Granatum, is a kind of Chinese medicine.For the pericarp of Punicaceae plant pomegranate, its is sour, puckery, bitter.With relieving diarrhea with astringents, stop
The effect of blood, expelling parasite, for chronic diarrhea, protracted dysentery, has blood in stool, rectal prolapse, uterine bleeding, under band, abdominal pain due to enterositosis.Due to granatum bitter, relate to, mouth
Feel bad, be directly used as medicine or be added in food or feed, can all be difficult to swallow.
The content of the invention:
It is an object of the invention to provide a kind of composition for treating bacillary intestinal inflammatory, is asked with solving above-mentioned technology
Topic.
The technical problems to be solved by the invention are realized using following technical scheme:
A kind of composition for treating bacillary intestinal inflammatory, it is characterised in that prepared by the Chinese medicine material of following parts by weight
Form:
10 parts of granatum, 5 parts of folium artemisiae argyi, 3 parts of rhizoma atractylodis, 2 parts of cloves, 4 parts of Fructus Corni, 5 parts of the seed of Oriental arborvitae, 3 parts of Schisandra chinensis, polygala
2 parts, 8 parts of Radix Codonopsis, 5 parts of radix astragali, 3 parts of the root of Dahurain angelica, 5 parts of elscholtiza, 4 parts of felwort, 3 parts of radix bupleuri, 4 parts of Radix Paeoniae Alba;
What wherein granatum was selected is the granatum after de- bitterness, is concretely comprised the following steps:
(1) collect the granatum that strips down, be immersed in the water immersion 6-8 it is small when, granatum is saturated completely, granatum
It is waterlogged, bitter taste material can be separated out, while quick-frozen effect can be strengthened;
(2) granatum after soaking is placed in quick-frozen in less than -10 DEG C environment;More than when cooling time is 2 small, through overrunning
Freeze, granatum has enough hardness, can just cut out the thin slice met the requirements;
(3) cut into slices to the granatum after freezing, slice thickness is not more than 0.8mm, and granatum thin slice is made, and is cut into thin
Piece is fully separated out beneficial to bitter taste material, increases the area contacted with hydromel, improves the effect of Rapid Fermentation;
(4) granatum thin slice is soaked with warm water, 38-45 DEG C of water temperature, immersion 3-5min takes out immediately;
(5) after granatum thin slice takes out, immerse in hydromel, granatum thin slice is stained with hydromel and can be taken off, be placed in
In 35 ± 2 DEG C of environment, when spontaneous fermentation 16-20 is small, granatum thin slice is spread out, makes its surface natural air drying, spontaneous fermentation
It is the further key for reducing bitter taste material, using fermentation by bitter taste substance decomposition, while honey composition is as sweet taste
Agent, can improve the palatability of granatum;
(6) after air-drying, one layer of edible glycerol is coated on its surface, then with steam moisturizing 30min, edible glycerol can
As sweetener, at the same can be to avoid steam moisturizing during, the effective ingredient of granatum is lost in.
The water that immersion granatum uses in step (1), selects light salt brine, and light salt brine is dissolved in the water by salt and is formed, and eats
Salt concentration of ordinary dissolution is 1.2g/L, can increase the effect for removing granatum bitter taste using light salt brine immersion, and brine concentration is not easy
It is excessive, avoid damage to the active ingredient of granatum.
When granatum thin slice is soaked with warm water in step (4), a small amount of light-coloured vinegar can be added dropwise into warm water, light-coloured vinegar concentration is not
More than 0.6g/L, a small amount of light-coloured vinegar is added dropwise in warm water, there is the effect of softening granatum, while can further mitigate the bitterness of granatum
Taste.
The beneficial effects of the invention are as follows:
The composition of the bacillary intestinal inflammatory for the treatment of provided by the invention, for treating bacillary intestinal inflammatory good effect,
Control difficulty in relapse after healing, the granatum in composition is by repeatedly de- bitterness, including the means such as infiltration separates out, fermentation is decomposed, most
Achieve the purpose that granatum takes off bitterness eventually, while improve the mouthfeel of granatum by honey and edible glycerol, can greatly reduce
The pain of medication.
Embodiment:
In order to make the technical means, the creative features, the aims and the efficiencies achieved by the present invention easy to understand, tie below
Specific embodiment is closed, the present invention is further explained.
Embodiment 1
A kind of composition for treating bacillary intestinal inflammatory, it is characterised in that prepared by the Chinese medicine material of following parts by weight
Form:
Granatum 10g, folium artemisiae argyi 5g, rhizoma atractylodis 3g, cloves 2g, Fructus Corni 4g, seed of Oriental arborvitae 5g, Schisandra chinensis 3g, polygala 2g, Radix Codonopsis
8g, radix astragali 5g, root of Dahurain angelica 3g, elscholtiza 5g, felwort 4g, radix bupleuri 3g, Radix Paeoniae Alba 4g;
What wherein granatum was selected is the granatum after de- bitterness, and granatum takes off concretely comprising the following steps for bitterness:
Collect the granatum that strips down, be immersed in the water immersion 6-8 it is small when, granatum is saturated completely, granatum quilt
Water saturates, can separate out bitter taste material, while can strengthen quick-frozen effect;
Granatum after immersion is placed in quick-frozen in less than -10 DEG C environment;More than when cooling time is 2 small, process is quick-frozen, stone
Pomegranate leatherware has enough hardness, can just cut out the thin slice met the requirements;
Cut into slices to the granatum after freezing, slice thickness is not more than 0.8mm, and granatum thin slice is made, thinly slices
Fully separated out beneficial to bitter taste material, increase the area contacted with hydromel, improve the effect of Rapid Fermentation;
Granatum thin slice is soaked with warm water, 38-45 DEG C of water temperature, immersion 3-5min takes out immediately;
After granatum thin slice takes out, immerse in hydromel, granatum thin slice is stained with hydromel and can be taken off, it is placed in 35 ±
In 2 DEG C of environment, when spontaneous fermentation 16-20 is small, granatum thin slice is spread out, makes its surface natural air drying, spontaneous fermentation be into
One step reduces the key of bitter taste material, and using fermentation by bitter taste substance decomposition, while honey composition is as sweetener, can
To improve the palatability of granatum;
After air-drying, one layer of edible glycerol is coated on its surface, then can be made with steam moisturizing 30min, edible glycerol
For sweetener, at the same can be to avoid steam moisturizing during, the effective ingredient of granatum is lost in.
Clinical test:
(1) clinical data
Applicant so far, carried out clinical observation treatment, wherein man in 2010 to 200 bacillary intestinal inflammatory patients
100, female 100, the age is between 16~75 years old.
(2) treatment method:
Using the composition of the embodiment of the present invention 1, routinely decocting for Chinese herbal medicine method, is decocted with water, and filtering extracting liquid takes orally,
One portion per day, in three times, one after each meal, 10 days as one therapeutic course.Treatment time, patients with mild clothes are calculated according to conditions of patients weight
With 2~3 courses for the treatment of, severe case, which even served 6~10 courses for the treatment of, to fully recover.
(3) efficacy assessment standard:
Present invention is mainly used for the bacillary inflammatory bowel disease for the treatment of, therefore symptom improves situation and every Testing index conduct
Curative effect judging standard, is divided into following four:
Cure:Abdominal pain, diarrhea symptom disappear, stool shaping, daily 1~2 time, and primary symptom, the minor symptom of TCM syndrome disappear, tongue
Tongue returns to normal, its relevant objective indicator is close normal with the relevant disease of diarrhea.
It is effective:Daily 2~3 times of times of defecation, approximation shaping, or loose stool is daily only once, primary symptom, the minor symptom of TCM syndrome
Improvement degree has clear improvement more than 2 grades with the relevant objective indicator of diarrhea.
Effectively:Times of defecation and matter, primary symptom, the minor symptom of TCM syndrome take a favorable turn, and have with the relevant objective indicator of diarrhea
Improve.
It is invalid:Symptom is without improving or aggravating, with the relevant objective indicator of diarrhea without improvement.
(4) therapeutic effect:
Clinical cure 164, effective 22, effective 8, invalid 6, all cases have no adverse reaction.
(5) summarize:
Clinical time:4-5, curative effect:10 days effectively, the course for the treatment of:General patient 20 days, symptom disappears substantially, patient with severe symptoms:
Illness disappears within 60 days, and symptom all disappears within 100 days.Effective percentage 98%, cure rate 82%.
The present invention prepares simply, and good absorption effect is evident in efficacy, without side-effects, safe, is conducive to sufferer and subtracts in time
Hypopathia shape.
Basic principle, main feature and the advantages of the present invention of the present invention has been shown and described above.The technology of the industry
For personnel it should be appreciated that the present invention is not limited to the above embodiments, described in the above embodiment and specification is only the present invention
Preference, be not intended to limit the present invention, without departing from the spirit and scope of the present invention, the present invention also have it is various
Changes and improvements, these changes and improvements all fall within the protetion scope of the claimed invention.The claimed scope of the invention is by institute
Attached claims and its equivalent thereof.