Invention content
The purpose of the present invention is to provide a kind of Chinese medicine compositions for treating Qi dysfunction in blood control type purpura, have and take effect
Soon, the advantages that low, toxic side effect is small, uneasy to recur is spent.
A kind of Chinese medicine composition for treating Qi dysfunction in blood control type purpura, principle active component group become:Radix Astragali, party
Ginseng, radix polygonati officinalis, Chinese yam, moutan bark, hairyvein agrimony, Radix Paeoniae Alba, donkey-hide gelatin, Flos Albiziae, windproof, bletilla, rhizoma nelumbinis, hawthorn, Radix Glycyrrhizae, jujube.
Described, a kind of Chinese medicine composition for treating Qi dysfunction in blood control type purpura, by the bulk pharmaceutical chemicals of following parts by weight
It is made:Radix Astragali 20-35, Radix Codonopsis 20-35, radix polygonati officinalis 15-25, Chinese yam 15-25, moutan bark 12-18, hairyvein agrimony 12-18, Radix Paeoniae Alba 12-
18, donkey-hide gelatin 3-9, Flos Albiziae 8-15, windproof 8-15, bletilla 8-15, rhizoma nelumbinis 8-15, hawthorn 8-15, Radix Glycyrrhizae 8-15, jujube 8-15.
Preferably, a kind of Chinese medicine composition for treating Qi dysfunction in blood control type purpura, by the bulk pharmaceutical chemicals of following parts by weight
It is made:It is Radix Astragali 25, Radix Codonopsis 25, radix polygonati officinalis 20, Chinese yam 20, moutan bark 15, hairyvein agrimony 15, Radix Paeoniae Alba 15, donkey-hide gelatin 6, Flos Albiziae 10, windproof
10, bletilla 10, rhizoma nelumbinis 10, hawthorn 10, Radix Glycyrrhizae 10, jujube 10.
The pharmacological property of Chinese medicine composition each component of the present invention is as follows.
Radix Astragali:Nature and flavor:It is sweet, tepor.Return lung, spleen, liver and kidney channel.Radix Astragali has invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, sore
The effect of myogenic.For treatment deficiency of vital energy weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, ulcer hardly possible
It bursts, burst for a long time and does not holds back, blood deficiency chlorosis, Heat Diabetes.《This warp》It records:" main ulcer loses sore, Apocenosis pain relieving long.Qi-restoratives, little Er Bai
Disease.”《Japan hanako materia medica》It records:It " helps gas to strengthen the bone, puts on flesh and enrich blood.”.Modern Chinese herbal medicine pharmaceutical research thinks the main of Radix Astragali
Ingredient is astragalus polyose, can enhance the ability that specific immunity and non-characteristic are immunized, can increase Rat Erythrocytes number, promote to make
The proliferation of hemocytoblast.The root of legume astragalus mongolicus is selected in the present invention, it is raw to use.
Radix Codonopsis:It is sweet in flavor, it is mild-natured.Returns spleen, lung channel;Matter moisten gas and, there is strengthening the spleen and tonifying the lung, the effect of nourishing qi and blood promotes the production of body fluid.It is main
Weakness of the spleen and the stomach, anorexia and loose stool, lassitude hypodynamia are controlled, the deficiency syndrome of the lung is breathed with cough, shortness of breath lazyness speech, spontaneous perspiration, and blood deficiency chlorosis is thirsty.Modern study, party
Ginseng contain various saccharides, phenols, sterol, volatile oil, scutellarein glucosid, saponin and Alkaloid, have strengthen immunity,
It expands blood vessel, decompression, improve the effects that microcirculation, enhancing hematopoiesis function, have in addition to leucocyte decline caused by chemotherapy radiotherapy
Castering action.The present invention selects the dry root of Campanulaceae Radix Codonopsis, raw to use.
Radix polygonati officinalis:For the rhizome of liliaceous plant radix polygonati officinalis.It is sweet in flavor, it is mild-natured.It attaches to the lung and stomach meridians.With nourishing Yin and moistening lung, nourishing the stomach to improve the production of body fluid
The effect of.It cures mainly:Cough caused by dryness;Overstrain cough;Pyreticosis yin-fluid consumes the dry throat and mouth of wound;Heat Diabetes;Deficiency of Yin diseases caused by external factors;Dizzy dizziness;Tendon and vessel
Contraction pain.《Guangxi Chinese medicinal herbal》It records:" nourishiing yin to clear away the lung-heat is moisturized.Control the deficiency of Yin, hidrosis, cough caused by dryness, consumptive lung disease.”.The present invention selects Liliaceae
The rhizome of plant radix polygonati officinalis, it is raw to use.
Chinese yam:It is sweet in flavor, it is mild-natured.Returns spleen, lung, kidney channel.Can tonifying spleen nourishing the stomach, engender liquid and benefic lung, the puckery essence of kidney tonifying.It is usually used in spleen deficiency food
Few, endless diarrhea, the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, and under band, frequent micturition, abnormal heat is quenched one's thirst.The present invention selects the dry of Dioscoreaceae plant Chinese yam
Dry rhizome.Root head is cut, is cleaned, crust and fibrous root are removed, it is dry after being smoked with Sulfur.
Moutan bark:Cold in nature, bitter is cool, is slightly cold.The thoughts of returning home, liver, kidney, lung channel.There is the effect of clearing heat and cooling blood, promoting blood circulation to remove blood stasis.It is main
It controls:Warm heat disease heat invading xuefen;Macular eruption;Hematemesis;Pyreticosis later stage hot Fu Yin distributions heat;Deficiency of Yin osteopyrexia and fever;Amenorrhea due to stagnation of blood;Dysmenorrhoea;
Carbuncle sore tumefacting virus;The pain of injury caused by falling and tumbling;Beriberoid pyretic arthralgia.Frequently as blood-cooling drugs, sharp water medicine, anti-dampness drug.The present invention selects ranunculaceae plant male
Red dry root skin, dries and is used as medicine.
Hairyvein agrimony:Hardship, cool, acrid flavour, puckery, property partial temperature, enter lung, liver, spleen three pass through, can clearing heat and cooling blood hemostasis, can give birth to it is Kidney-Yin it
It is empty.This grass hemostasis and blood, and energy help astringing to arrest bleeding, performance is not flat inclined, therefore cold, hot bleeding can apply, and have tonifying spleen
The effect of QI invigorating is robustness astringing to arrest bleeding agent.Hairyvein agrimony contains agrimonine, it can be such that reduced clotting time, blood platelet increases,
Have cardiac effect concurrently.The present invention selects hairyvein agrimony herb to clean, and dries, segment, raw to use.
Radix Paeoniae Alba:Cool in nature, bitter acid is slightly cold, there is enrich blood soft liver, smooth liver and relieve pain, hold back cloudy receipts sweat and other effects.Suitable for the deficiency of Yin
Fever, irregular menstruation, chest and abdomen pain over the hypochondriac region, four limbs contractions are anxious, diarrhea dysentery abdominal pain, spontaneous sweating, uterine bleeding, with inferior disease.Contain in Radix Paeoniae Alba
There is Paeoniflorin to have antibacterial, antipyretic, anti-inflammatory, increase coronary flow, improvement myocardial nutritional flow, expansion blood vessel, confrontation acute
Myocardial ischemia inhibits platelet aggregation, calmness, analgesia, spasmolysis, antiulcer, the effect for adjusting blood glucose.Radix Paeoniae Alba decoction can inhibit dysentery
Shigella, streptococcus pneumonia, Escherichia coli, typhoid bacillus, hemolytic streptococcus, Pseudomonas aeruginosa etc. are selected fry in the present invention
Radix Paeoniae Alba.
Donkey-hide gelatin:It for traditional nourishing, top grade of enriching blood, can enrich blood, stop blooding, nourishing Yin and moistening dryness.The present invention select Shandong Donga Ah
The donkey-hide gelatin of glue limited liability company production.It is ground into fine-powdered, it is spare.
Flos Albiziae:Nature and flavor sweet and neutral, have Shu Yu, qi-regulating, tranquilizing the mind, active, blood-nourishing, enriching yin kidney, clear away heart-fire improving eyesight the effect of.This
Invention selects the flower of celastrus orbiculatus section silk tree to be used as medicine.
It is windproof:Acrid flavour, sweet, slightly warm in nature.Return bladder, liver, the spleen channel.It expels pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, the work(that relieving convulsion is jerked surely
Effect.It cures mainly:Diseases caused by external factors exterior syndrome, rubella itch, arthralgia pain due to rheumatism, lockjaw.The present invention selects Umbelliferae herbaceos perennial windproof
Root.It is raw to use.
Bletilla:It is pungent, it is bitter, sweet, puckery, it is slightly cold.Return lung, liver, stomach.Frequently as drug for invigorating blood circulation and eliminating stasis.Modern research shows that the bletilla striata
Blood platelet factor III activity can be enhanced, significantly shorten the clotting time and factor forms the time, inhibit fibrinolysin
Activity has anastalsis to local hemorrhage;Animal experiments show that bletilla water extraction is to parenchymatous organ(Liver, spleen), muscle blood
The external applications bletilla striata haemostatic effect such as angiorrbagia is quite good.In addition, research shows that bletilla can also protect gastric mucosa, antibacterial, anticancer and anti-cancer
Effect.The present invention selects the dry tuber for orchid bletilla, shave to dry, raw to use.
Rhizoma nelumbinis:For lotus root coupling part, mild-natured, sweet-puckery flavor.Containing asparagine, tannin etc., there is higher medical value, medicine
With the bleeding time can be shortened, there is the benefits of hemostasis scattered silt, controls hemoptysis, haematemesis, hematuria, has blood in stool, uterine hemorrhage etc..The present invention selects
The loose rhizome of nymphaeaceae plant lotus.Fibrous root is removed, is dried, it is raw to use.
Hawthorn:Sour warm-natured, qi and blood is simultaneously walked, and without hindering new blood, row stagnant gas is applied to meat stagnation without hindering healthy tendency for stagnation resolvation
Card, diarrhea dysentery abdominal pain, stasis of blood pectoralgia, lochiorrhagia, dysmenorrhoea, spit blood, have blood in stool at hernia pain.Modern times are applied alone this product preparation to control
Angiocardiopathy, bacillary dysentery etc. are treated, there is good therapeutic effect.Hawthorn mainly contains flavonoids, oligomeric flavanoids, organic acid
In addition class, trace element also have containing ingredients such as triterpenes, steroid and organic amines.The present invention selects haw berry decontamination,
Slice, dries and is used as medicine.
Radix Glycyrrhizae:Sweet tea sweet in flavor, it is mild-natured and, enter the heart, spleen, lung, stomach four pass through.It is raw with cooler, can purging intense heat and detonicating, relieving spasm to stop pain.It is sweet
Grass is also good at mediation property of medicine, solves the poison of hundred medicines.Licorice is used in the present invention.
Jujube:Sweet, warm.Returns spleen, stomach.It strengthens the spleen and stomach, yin and blood nourishing, mental-tranquilization mitigates pharmacological property, softens blood vessel,
Hypertension is prevented, treats anaphylactoid purpura, auxiliary treatment hepatic sclerosis and other effects is aftercare good merchantable brand.Clinical studies show:It is red
Triterpene compound contained by jujube and cyclic adenosine monophosphate have stronger anticancer, anti-allergic effects.Can enhance muscular strength, eliminate it is tired
Labor, increases myocardial contractive power, improves myocardial nutrition expansion blood vessel, has good effect to prevention disease of cardiovascular system;To slow
The illnesss such as property hepatitis, hepatic sclerosis, anaemia, anaphylactoid purpura have good therapeutic effect.The present invention selects Removing Kernel for Date, dries, raw to use.
Chinese medicine thinks that the Basic disease cause interpretation of the cause, onset and process of an illness of Qi dysfunction in blood control type purpura is:This type disease position is in heart spleen, heart governing blood and vessels, spleen master
Unite blood, the insufficiency of heart and spleen has under one's command and haves no right, blood extravasation of blood and wander away and do not return, then see various bleedings performances.Qi as the commander of blood, blood being the mother of qi,
Hemorrhage bleeding is felt frustrated, it is seen that dizzy, weak, palpitaition, shortness of breath, colourless, pale tongue, tongue are white, weak pulse be one deficiency of vital energy and blood as.This hair
Bright Chinese medicine composition is technical solution with " replenishing qi to invigorate the spleen, take the photograph blood hemostasis ".Radix Astragali and Radix Codonopsis are reused in side, it is auxiliary with air making-up and spleen enlivening
With radix polygonati officinalis nourishing Yin and moistening lung, nourishing the stomach to improve the production of body fluid, add with Chinese yam boosting qi and nourishing yin, astringing to arrest bleeding, moutan bark clearing heat and cooling blood, hairyvein agrimony cool blood is stopped
Blood, stir-baked RADIX PAEONIAE ALBA, which is enriched blood, holds back cloudy blood-arresting catamenia-regulating, the hemostasis of donkey-hide gelatin nourishing yin and supplementing blood, with Flos Albiziae qi-regulating, active, tranquilizing the mind, makes with Radix Glycyrrhizae, greatly
Jujube and stomach invigorating the spleen, as a means of biochemistry, flourishing of QI leading to sufficiency of blood and channel tropism play the work(for the blood hemostasis that replenishes qi to invigorate the spleen, takes the photograph altogether.Add with windproof wind-dispelling
Inducing diaphoresis, bletilla is promoting blood circulation and removing blood stasis, rhizoma nelumbinis hemostasia and dissipation blood stasis, hawthorn regulating qi to disperse stagnation, reaches controlling of bleeding with astringents jointly and does not stay the stasis of blood, thoroughly eliminates spot
The effect of block.
The above all medicines share, each pharmacological property cooperate, are all linked with one another, playing replenish qi to invigorate the spleen altogether, take the photograph the work(of blood hemostasis, reach jointly
To the purpose for curing Qi dysfunction in blood control type purpura.
Preparation, instructions of taking and dosage:
Present invention side is taken, 80-200 mesh sieve is crushed, is impregnated 30-60 minutes with 8-10 times of cold water.First pass intense fire is fried boiling,
Change slow boiling to be fried boiling 30 minutes, filters out filtrate.Second time, into the dregs of a decoction plus 4-5 times of water, intense fire are fried boiling, change slow boiling and be fried boiling 40 minutes,
Filter out filtrate.Twice of filtrate mixing is to get Chinese medicine composition of the present invention.It warmly takes within 30 minutes after morning and evening dinner at twice, every time
150ml.It is peppery that raw meat is avoided eating during medication.
In the following, the present invention is specifically addressed in conjunction with specific embodiments.
Embodiment 3:
(1)Weigh 25 grams of Radix Astragali, 25 grams of Radix Codonopsis, 20 grams of radix polygonati officinalis, 20 grams of Chinese yam, 15 grams of moutan bark, 15 grams of hairyvein agrimony, Radix Paeoniae Alba
15 grams, 6 grams of donkey-hide gelatin, 10 grams of Flos Albiziae, 10 grams windproof, 10 grams of bletilla, 10 grams of rhizoma nelumbinis, 10 grams of hawthorn, 10 grams of Radix Glycyrrhizae, jujube 10
Gram;
(2)The Chinese medicine composition crushing of above-mentioned weight is sieved with 100 mesh sieve, is impregnated 50 minutes with 10 times of cold water.First pass is military
Fire is fried boiling, and changes slow boiling and is fried boiling 30 minutes, filters out filtrate.Second time, into the dregs of a decoction plus 4 times of water, intense fire is fried boiling, and changes slow boiling and is fried boiling 40
Minute, filter out filtrate.Twice of filtrate mixing is to get Chinese medicine composition of the present invention.
The curative effect of the present invention is verified below by clinical trial.
Clinical data
1.1 case selection:
48 observation cases are the anti-station outpatient service purpura patient of in April, 2010 Linyi City of in September, -2013 Tancheng County skin, are met
《People's Republic of China's traditional Chinese medicine industry standard --- Chinese medical disease Standardization of diagnosis and curative effect》(ZY/T001.1~001.9-94)Have
Close Qi dysfunction in blood control type purpura diagnostic criteria.Wherein man 22, female 26,6~31 years old age, average age 14 years old;With skin
Purpura is primary symptom, and color is in secretly blue patch.With dizzy, weak, colourless, pale tongue, tongue is thin white, and arteries and veins is thin and delicate to wait diseases.
1.2 therapy:
Give patient's Chinese medicine composition of the present invention, warmly takes within 30 minutes after morning and evening dinner at twice, each 150ml.During medication
It is peppery to avoid eating raw meat.Continuously take 2 weeks.
1.3 efficacy assessment standard:
According to《People's Republic of China's traditional Chinese medicine industry standard --- Chinese medical disease Standardization of diagnosis and curative effect》(ZY/T001.1
~001.9-94)It drafts:
It cures:Purple plague purpura purple point and constitutional symptom disappear, and lab index restores normal;
It improves:Cyanosis of skin spot significantly reduces, and constitutional symptom mitigates, and lab index has improvement;
It is not cured:Cyanosis of skin spot, constitutional symptom and lab index are unchanged;
Effective percentage is the sum of cure rate, improvement rate.
1.4 treatment results
48 patients cure 37 (77.08%), improve 10 (20.83%), more 1 (2.08%), effective percentage are not
97.92%.Follow-up observation is carried out over the course for the treatment of for 48 patients, does not find that apparent adverse reaction, worth clinic push away
Extensively.