CN104856781A - Experimental animal smudging molding box and molding method thereof - Google Patents
Experimental animal smudging molding box and molding method thereof Download PDFInfo
- Publication number
- CN104856781A CN104856781A CN201510335138.1A CN201510335138A CN104856781A CN 104856781 A CN104856781 A CN 104856781A CN 201510335138 A CN201510335138 A CN 201510335138A CN 104856781 A CN104856781 A CN 104856781A
- Authority
- CN
- China
- Prior art keywords
- sootiness
- modeling case
- modeling
- box
- smudging
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
- A61D7/04—Devices for anaesthetising animals by gases or vapours; Inhaling devices
-
- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
- G09B23/30—Anatomical models
-
- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/36—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for zoology
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Housing For Livestock And Birds (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
The invention discloses an experimental animal smudging molding box and a molding method thereof. The experimental animal smudging molding box comprises an experimental animal smudging molding box body; the experimental animal smudging molding box body comprises a smudging molding box, a smudging monitoring box, a drawing rod, a smog concentration detector, a vent hole, a fan and a cover, wherein the smudging monitoring box is arranged in the smudging molding box and consists of a smudging groove and a detector box, the smog concentration detector is arranged in the detector box, and an ignited cigarette is inserted into the smudging groove; the vent holes are formed in another side of the smudging molding box, and the fan is arranged in the vent hole in an inserting way; the cover is arranged at the upper end plane of the smudging molding box, the lower end of the drawing rod is inserted into the smudging molding box and is connected with the smudging monitoring box, and the upper end of the drawing rod penetrates through the cover and extends to the upper part of the smudging monitoring box. The experimental animal smudging molding box provided by the invention is easy to operate, cheap in price, the smog concentration can be more uniform and can be monitored and adjusted at any time; furthermore, an experimental animal COPD (Chronic Obstructive Pulmonary Disease) model can be prepared in a more standard way, and the molding success ratio is higher.
Description
Technical field
The present invention relates to medical skill experiment field, particularly relate to a kind of laboratory animal sootiness modeling case and modeling method thereof.
Background technology
Current sootiness modeling method mainly contains mouth and nose formula exposure system and whole-body type exposure system; Mouth and nose formula exposure system adopts tower cavity structure, expose storehouse its aeration of formula system and gaseous mass poor, not easily carry out gas precision data monitoring and adjustment; Not easy to clean and reuse, easily waste resource and not environmentally; Modeling success rate is low, can not the active situation of animal in Real Time Observation experimentation.
Summary of the invention
Object of the present invention: a kind of laboratory animal sootiness modeling case and modeling method thereof are provided, for chronic obstructive pulmonary disease (chronic obstructive pulmonary disease, be called for short COPD) preparation of animal model, test for preclinical medicine relevant animal.
To achieve these goals, technical scheme of the present invention is:
A kind of laboratory animal sootiness modeling case, comprises sootiness modeling case, sootiness monitor box, pumping rod, smokescope survey meter, ventilation mouth, fan and lid; Described sootiness modeling case is closed body structure, and four sides of described sootiness modeling case are free relief surface; Described sootiness monitor box is arranged in described sootiness modeling case, be positioned at the middle part of described sootiness modeling case, described sootiness monitor box is made up of sootiness groove and box detector, described sootiness groove is arranged on the top of described box detector, described smokescope survey meter is arranged in described box detector, and the medicated cigarette of lighting is inserted in described sootiness groove; Described ventilation mouth is arranged on the opposite side of described sootiness modeling case, is positioned at the bottom of described sootiness modeling case, and described fan embeds and is arranged on described ventilation mouth; Described lid embeds and is arranged on the upper surface of described sootiness modeling case, is positioned at the top of described sootiness monitor box; The lower end of described pumping rod is inserted in described sootiness modeling case, and is connected with described sootiness monitor box, and the upper end of described pumping rod extends to the top of described sootiness modeling case through described lid.
Above-mentioned laboratory animal sootiness modeling case, wherein, described sootiness modeling case and active face are respectively equipped with multiple air vent, described air vent is centered around around described sootiness groove.
Above-mentioned laboratory animal sootiness modeling case, wherein, described air vent and ventilation mouth are by preservative film or sealing-plug sealing.
Above-mentioned laboratory animal sootiness modeling case, wherein, described sootiness modeling case is made up of the transparent high temperature resistant material of waterproof fireproofing.
Above-mentioned laboratory animal sootiness modeling case, wherein, the outside of described fan is provided with adsorption box, and described adsorption box is flexibly connected with described sootiness modeling case, is provided with active carbon in the outboard end of described adsorption box.
A modeling method for laboratory animal sootiness modeling case, the method at least comprises the steps:
Step 1: put into the medicated cigarette of lighting in described sootiness groove.
Step 2: install described smokescope survey meter and open in described sootiness modeling case, setting target concentration value and alarming value simultaneously.
Step 3: the concentration of the described monitoring of smokescope survey meter carbon monoxide, sulfur dioxide and oxygen.
Step 4: after carbon monoxide, sulfur dioxide and oxygen reach aimed concn in described sootiness modeling case, open the fan on described ventilation mouth.
Step 5: the wind speed of the fan described in adjustment, makes carbon monoxide, sulfur dioxide and oxygen concentration in described sootiness modeling case remain in target zone.
Step 6: laboratory animal is put into described sootiness modeling case and carry out sootiness modeling experiment, taking-up after completing.
Step 7: the smog in described sootiness modeling case is drained rear closedown by described fan.
The present invention is simple to operate, low price, and smokescope can be made more homogeneous, and smokescope can carry out monitoring and regulating at any time; Can the more standardized preparation carrying out laboratory animal COPD model; Modeling success rate is high.
Accompanying drawing explanation
Fig. 1 is the structural representation of laboratory animal sootiness modeling case of the present invention.
Fig. 2 is the flow chart of the modeling method of laboratory animal sootiness modeling case of the present invention.
Detailed description of the invention
Embodiments of the invention are further illustrated below in conjunction with accompanying drawing.
Refer to shown in accompanying drawing 1, a kind of laboratory animal sootiness modeling case, comprises sootiness modeling case 1, sootiness monitor box 2, pumping rod 3, smokescope survey meter 4, ventilation mouth 5, fan 6 and lid 7; Described sootiness modeling case 1 is the body structure closed, and four sides of described sootiness modeling case 1 are free relief surface; Described sootiness monitor box 2 is arranged in described sootiness modeling case 1, be positioned at the middle part of described sootiness modeling case 1, described sootiness monitor box 2 is made up of sootiness groove 21 and box detector, described sootiness groove 21 is arranged on the top of described box detector, described smokescope survey meter 4 is arranged in described box detector, and the medicated cigarette of lighting is inserted in described sootiness groove 21; Described ventilation mouth 5 is arranged on the opposite side of described sootiness modeling case 1, is positioned at the bottom of described sootiness modeling case 1, and described fan 6 embeds and is arranged on described ventilation mouth 5; Described lid 7 embeds and is arranged on the upper surface of described sootiness modeling case 1, is positioned at the top of described sootiness monitor box 2; The lower end of described pumping rod 3 is inserted in described sootiness modeling case 1, and is connected with described sootiness monitor box 2, and the upper end of described pumping rod 3 extends to the top of described sootiness modeling case 1 through described lid 7.
Described sootiness modeling case 1 and active face 2 are respectively equipped with multiple air vent 8, and described air vent 8 is centered around described sootiness groove 3 around.
Described air vent 8 and ventilation mouth 5 by preservative film or sealing-plug sealing, can keep closing of sootiness modeling case 1, also in sootiness modeling case 1, are filled with nitrogen by air vent 8 and are used for reducing oxygen concentration, cause low-oxygen environment.
Described sootiness modeling case 1 is made up of the transparent high temperature resistant material of waterproof fireproofing.Free relief surface can freely be dismantled, and is convenient to modeling experiment and terminates rear cleaning sootiness modeling case 1 environment, make it reuse.
The outside of described fan 6 is provided with adsorption box 9, and described adsorption box 9 is flexibly connected with described sootiness modeling case 1, is provided with active carbon 10, for adsorbing flue dust in the outboard end of described adsorption box 9.The active carbon that active carbon 10 can adopt vehicle exhaust to adsorb, use more environmental protection, adsorption box 9 can be dismantled.
Sootiness monitor box 2 is mentioned by pumping rod 3 by the present invention, is convenient to deposit medicated cigarette and smokescope survey meter 4.
Refer to shown in accompanying drawing 2, a kind of modeling method of laboratory animal sootiness modeling case, the method at least comprises the steps:
Step 1: put into the medicated cigarette of lighting in described sootiness groove 3.
Step 2: the smokescope survey meter 4 described in installing in described sootiness modeling case 1 is also opened, and sets target concentration value and alarming value simultaneously.Aimed concn and alarming value can need setting by experiment operator according to different experiments.
Step 3: the concentration of carbon monoxide, sulfur dioxide and oxygen etc. monitored by described smokescope survey meter 4.
Step 4: after carbon monoxide, sulfur dioxide and oxygen reach aimed concn in described sootiness modeling case 1, open the fan 6 on described ventilation mouth 5.
Step 5: the wind speed of the fan 6 described in adjustment, makes carbon monoxide, sulfur dioxide and oxygen concentration in described sootiness modeling case 1 remain in target zone.The target zone of carbon monoxide and sulfur dioxide concentration needs setting by experiment operator according to different experiments.
Step 6: laboratory animal is put into described sootiness modeling case 1 and carry out sootiness modeling experiment, taking-up after completing.The laboratory animal smoke fumigating time of putting into sootiness modeling case 1 to be adjusted in practical operation by experiment operator and determines.
Step 7: the smog in described sootiness modeling case 1 is drained rear closedown by described fan 6.
The present invention is the modeling Smoke fumigating box of laboratory animal COPD, and the smokescope of sootiness is controlled, and the casing of transparent material can clearly observation experiment process.
In sum, the present invention is simple to operate, low price, and smokescope can be made more homogeneous, and smokescope can carry out monitoring and regulating at any time; Can Real Time Observation animal activity situation by transparent cabinet; Can the more standardized preparation carrying out laboratory animal COPD model; Modeling success rate is high.
The foregoing is only the preferred embodiments of the present invention; not thereby the scope of the claims of the present invention is limited; every equivalent structure transformation utilizing description of the present invention to do; or directly or indirectly use the technical field being attached to other Related products, be all in like manner included in scope of patent protection of the present invention.
Claims (6)
1. a laboratory animal sootiness modeling case, is characterized in that: comprise sootiness modeling case, sootiness monitor box, pumping rod, smokescope survey meter, ventilation mouth, fan and lid; Described sootiness modeling case is closed body structure, and four sides of described sootiness modeling case are free relief surface; Described sootiness monitor box is arranged in described sootiness modeling case, be positioned at the middle part of described sootiness modeling case, described sootiness monitor box is made up of sootiness groove and box detector, described sootiness groove is arranged on the top of described box detector, described smokescope survey meter is arranged in described box detector, and the medicated cigarette of lighting is inserted in described sootiness groove; Described ventilation mouth is arranged on the opposite side of described sootiness modeling case, is positioned at the bottom of described sootiness modeling case, and described fan embeds and is arranged on described ventilation mouth; Described lid embeds and is arranged on the upper surface of described sootiness modeling case, is positioned at the top of described sootiness monitor box; The lower end of described pumping rod is inserted in described sootiness modeling case, and is connected with described sootiness monitor box, and the upper end of described pumping rod extends to the top of described sootiness modeling case through described lid.
2. laboratory animal sootiness modeling case according to claim 1, it is characterized in that: described sootiness modeling case and active face are respectively equipped with multiple air vent, described air vent is centered around around described sootiness groove.
3. laboratory animal sootiness modeling case according to claim 1 and 2, is characterized in that: described air vent and ventilation mouth are by preservative film or sealing-plug sealing.
4. laboratory animal sootiness modeling case according to claim 1, is characterized in that: described sootiness modeling case is made up of the transparent high temperature resistant material of waterproof fireproofing.
5. laboratory animal sootiness modeling case according to claim 1, is characterized in that: the outside of described fan is provided with adsorption box, and described adsorption box is flexibly connected with described sootiness modeling case, is provided with active carbon in the outboard end of described adsorption box.
6. utilize a modeling method for the laboratory animal sootiness modeling case described in claim 1, it is characterized in that: the method at least comprises the steps:
Step 1: put into the medicated cigarette of lighting in described sootiness groove;
Step 2: install described smokescope survey meter and open in described sootiness modeling case, setting target concentration value and alarming value simultaneously;
Step 3: the concentration of the described monitoring of smokescope survey meter carbon monoxide, sulfur dioxide and oxygen;
Step 4: after carbon monoxide, sulfur dioxide and oxygen reach aimed concn in described sootiness modeling case, open the fan on described ventilation mouth;
Step 5: the wind speed of the fan described in adjustment, makes carbon monoxide, sulfur dioxide and oxygen concentration in described sootiness modeling case remain in target zone;
Step 6: laboratory animal is put into described sootiness modeling case and carry out sootiness modeling experiment, taking-up after completing;
Step 7: the smog in described sootiness modeling case is drained rear closedown by described fan.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510335138.1A CN104856781B (en) | 2015-06-17 | 2015-06-17 | Experimental animal sootiness modeling case and its modeling method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510335138.1A CN104856781B (en) | 2015-06-17 | 2015-06-17 | Experimental animal sootiness modeling case and its modeling method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104856781A true CN104856781A (en) | 2015-08-26 |
| CN104856781B CN104856781B (en) | 2017-06-27 |
Family
ID=53903269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510335138.1A Expired - Fee Related CN104856781B (en) | 2015-06-17 | 2015-06-17 | Experimental animal sootiness modeling case and its modeling method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104856781B (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105455220A (en) * | 2016-01-08 | 2016-04-06 | 南京市口腔医院 | Device for stimulating human active smoking effect through experimental animal |
| CN106128254A (en) * | 2016-08-31 | 2016-11-16 | 阮峰 | A kind of smoke inhalation injury model equipment |
| CN106781950A (en) * | 2017-01-03 | 2017-05-31 | 中国人民解放军第八医院 | A kind of multi-functional smog for medical research is caused injury experimental facilities |
| CN111742883A (en) * | 2020-01-03 | 2020-10-09 | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | Construction method of lung and spleen qi deficiency allergic rhinitis combined animal model |
| CN113069240A (en) * | 2021-05-10 | 2021-07-06 | 西安培华学院 | Smoke recycling animal chronic obstructive disease testing device and method |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201404307Y (en) * | 2009-05-19 | 2010-02-17 | 江苏省人民医院 | Animal smoking device |
| CN202654264U (en) * | 2012-04-19 | 2013-01-09 | 宁波大学 | Device for manufacturing animal model of smoking chronic obstructive pulmonary disease |
| CN203042539U (en) * | 2012-12-25 | 2013-07-10 | 北京慧荣和科技有限公司 | Animal full-smoke exposing system |
| CN104306081A (en) * | 2014-11-11 | 2015-01-28 | 黑龙江省中医药科学院 | Rodent respiratory system exposure contamination device |
| CN204274716U (en) * | 2014-08-05 | 2015-04-22 | 中国人民解放军第四军医大学 | A kind of smoke inhalation is caused injury experimental provision |
| CN204744498U (en) * | 2015-06-17 | 2015-11-11 | 徐向前 | Experimental animals smokes and makes moulding box |
-
2015
- 2015-06-17 CN CN201510335138.1A patent/CN104856781B/en not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201404307Y (en) * | 2009-05-19 | 2010-02-17 | 江苏省人民医院 | Animal smoking device |
| CN202654264U (en) * | 2012-04-19 | 2013-01-09 | 宁波大学 | Device for manufacturing animal model of smoking chronic obstructive pulmonary disease |
| CN203042539U (en) * | 2012-12-25 | 2013-07-10 | 北京慧荣和科技有限公司 | Animal full-smoke exposing system |
| CN204274716U (en) * | 2014-08-05 | 2015-04-22 | 中国人民解放军第四军医大学 | A kind of smoke inhalation is caused injury experimental provision |
| CN104306081A (en) * | 2014-11-11 | 2015-01-28 | 黑龙江省中医药科学院 | Rodent respiratory system exposure contamination device |
| CN204744498U (en) * | 2015-06-17 | 2015-11-11 | 徐向前 | Experimental animals smokes and makes moulding box |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105455220A (en) * | 2016-01-08 | 2016-04-06 | 南京市口腔医院 | Device for stimulating human active smoking effect through experimental animal |
| CN105455220B (en) * | 2016-01-08 | 2016-11-30 | 南京市口腔医院 | A kind of device of laboratory animal simulation people actively smoking effect |
| CN106128254A (en) * | 2016-08-31 | 2016-11-16 | 阮峰 | A kind of smoke inhalation injury model equipment |
| CN106781950A (en) * | 2017-01-03 | 2017-05-31 | 中国人民解放军第八医院 | A kind of multi-functional smog for medical research is caused injury experimental facilities |
| CN111742883A (en) * | 2020-01-03 | 2020-10-09 | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | Construction method of lung and spleen qi deficiency allergic rhinitis combined animal model |
| CN113069240A (en) * | 2021-05-10 | 2021-07-06 | 西安培华学院 | Smoke recycling animal chronic obstructive disease testing device and method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104856781B (en) | 2017-06-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104856781A (en) | Experimental animal smudging molding box and molding method thereof | |
| CN103598025B (en) | Field in-situ continuous low-abundance 13CO2 isotope labeling device and method | |
| CN102423104B (en) | Method for storing tobacco leaves by way of mechanical regulation and manual nitrogen charging | |
| KR101583604B1 (en) | Apparatus for measuring carbon dioxide of plant and soil material | |
| CN204744498U (en) | Experimental animals smokes and makes moulding box | |
| CN201757749U (en) | Simulated sealed cabinet smoke contamination experiment device | |
| CN204203796U (en) | Controlled atmosphere automaton | |
| CN205694623U (en) | A kind of planting greenhouse of automatic ventilation | |
| CN203715288U (en) | Carbon dioxide generator for illumination incubator | |
| CN205216512U (en) | Vent gas treatment system in for compost fermentation | |
| CN207721926U (en) | A kind of Bioexperiment toy anaesthetic treatment device | |
| CN206744331U (en) | A kind of bio-safety feeding facility for quarantine procedures | |
| CN105493960B (en) | A kind of incubator reducing gas concentration lwevel | |
| CN204355498U (en) | A kind of microenvironment monitor controller for cultural relic conservation | |
| CN204087996U (en) | A kind of transformer breather | |
| CN105573386B (en) | The preservation exhibiting device and its preservation methods of exhibiting of a kind of woodcarving | |
| CN102388856A (en) | Fully-automatic animal euthanasia equipment | |
| CN205124626U (en) | Air supply equipment of livestock -raising | |
| CN105165497B (en) | One kind makes cigarette deinsectization equipment | |
| CN204274716U (en) | A kind of smoke inhalation is caused injury experimental provision | |
| CN208334962U (en) | A kind of controlled atmosphere control system for Grain Storage System | |
| CN109287330A (en) | A kind of energy saving and environment friendly greenhouse of agricultural planting | |
| CN109602516B (en) | CO in a closed environment2Control device and method | |
| CN205321002U (en) | Fumigation apparatus convenient to carry out entomogenous fungi inspection | |
| CN205459206U (en) | Device is put to death in experimental animals anesthesia |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| EXSB | Decision made by sipo to initiate substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170627 Termination date: 20180617 |