CN109602516B - CO in a closed environment2Control device and method - Google Patents
CO in a closed environment2Control device and method Download PDFInfo
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- CN109602516B CN109602516B CN201811606017.6A CN201811606017A CN109602516B CN 109602516 B CN109602516 B CN 109602516B CN 201811606017 A CN201811606017 A CN 201811606017A CN 109602516 B CN109602516 B CN 109602516B
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- 238000000034 method Methods 0.000 title claims description 16
- 241001465754 Metazoa Species 0.000 claims abstract description 18
- 239000003463 adsorbent Substances 0.000 claims abstract description 14
- 238000001514 detection method Methods 0.000 claims abstract description 9
- 238000004891 communication Methods 0.000 claims abstract description 4
- 229910052799 carbon Inorganic materials 0.000 claims description 9
- 238000009395 breeding Methods 0.000 claims description 8
- 230000001488 breeding effect Effects 0.000 claims description 8
- 230000005484 gravity Effects 0.000 claims description 7
- 230000000384 rearing effect Effects 0.000 claims description 7
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 6
- 238000007789 sealing Methods 0.000 claims description 3
- 239000007789 gas Substances 0.000 description 8
- 241000699670 Mus sp. Species 0.000 description 4
- 238000010171 animal model Methods 0.000 description 4
- 206010021143 Hypoxia Diseases 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000006461 physiological response Effects 0.000 description 2
- 238000001179 sorption measurement Methods 0.000 description 2
- NHBKXEKEPDILRR-UHFFFAOYSA-N 2,3-bis(butanoylsulfanyl)propyl butanoate Chemical compound CCCC(=O)OCC(SC(=O)CCC)CSC(=O)CCC NHBKXEKEPDILRR-UHFFFAOYSA-N 0.000 description 1
- 208000010444 Acidosis Diseases 0.000 description 1
- 206010010071 Coma Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 206010024264 Lethargy Diseases 0.000 description 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 206010041349 Somnolence Diseases 0.000 description 1
- 230000007950 acidosis Effects 0.000 description 1
- 208000026545 acidosis disease Diseases 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000006931 brain damage Effects 0.000 description 1
- 231100000874 brain damage Toxicity 0.000 description 1
- 208000029028 brain injury Diseases 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000007954 hypoxia Effects 0.000 description 1
- 230000001146 hypoxic effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
- A61D7/04—Devices for anaesthetising animals by gases or vapours; Inhaling devices
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Anesthesiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Housing For Livestock And Birds (AREA)
- Catching Or Destruction (AREA)
- Respiratory Apparatuses And Protective Means (AREA)
Abstract
The invention provides CO in a closed environment2The control device comprises a closed feeding box; a plurality of chambers disposed at the top within the habitat; a switch is arranged on one side of the cavity adjacent to the interior of the feeding box and used for controlling the communication between the interior of the cavity and the interior of the feeding box, and CO is suitable to be placed in the cavity2An adsorbent; the sensor is used for detecting CO in the feeding box2Content A1、CO2Generation rate of (A)2And O2And transmitting to a processor; the processor is based on the received A1、A2And B gives the area S: the detection unit is used for detecting the position of the animal in the feeding box and transmitting the control unit; the control unit adjusts the switch so that the sum of the areas of the openings at the bottom of the chamber above the location matches the area S. The invention has the advantages of safety, high control precision and the like.
Description
Technical Field
The invention relates to gas control, in particular to CO in a closed environment2The control device and method of (1).
Background
Generally, when some animal gas concentration model experiments are carried out, an animal raising box is used for isolating experimental animals from the external environment, and the gas model experiments of the animals are carried out through controlling the oxygen concentration. Since such rearing tanks are generally relatively closed and have a low gas exchange capacity, the CO2 gas produced by the metabolism of animals cannot be sufficiently discharged. The gas can be accumulated continuously, the concentration is increased continuously, the health of experimental animals is influenced, and even acidosis of the experimental animals is caused. The following table shows the relationship between the concentration and content of CO2 and the physiological response of the organism.
| CO2Concentration of | Physiological response |
| 350～450ppm | The same general outdoor environment |
| 350～1000ppm | Fresh air and smooth breath |
| >10,00ppm | The air was turbid and the drowsiness began to be felt |
| >20,00ppm | Headache, lethargy, dull, inattentive, accelerated heartbeat, mild nausea |
| >50,00ppm | Can lead to severe hypoxia, permanent brain damage, coma, and even death |
At present, CO reduction2The concentration method mainly comprises the following two methods:
1. gas dilution, i.e. by injection of N2To dilute CO in a specific space2And through O2The control of the concentration reaches a target value. The main disadvantages of this approach are:
due to CO2The limit value of (A) is in the ppm level, a large amount of N needs to be injected2And O2To reduce CO2The concentration of (2) is high, the cost is high, and the efficiency is low.
2. Directly putting a large amount of adsorbent for adsorption. The disadvantages of this approach are:
the utilization rate of the adsorbent is not high, which causes waste.
Disclosure of Invention
In order to overcome the defects in the prior art, the invention provides CO in a closed environment2The control device improves the utilization rate of the adsorbent and reduces the cost.
The purpose of the invention is realized by the following technical scheme:
CO in closed environment2The control device comprises a closed feeding box; CO in the closed environment2The control device of (1) further comprising:
a plurality of chambers disposed at the top of the feeding box; a switch is arranged on one side of the cavity adjacent to the interior of the feeding box and used for controlling the communication between the interior of the cavity and the interior of the feeding box, and CO is suitable to be placed in the cavity2An adsorbent;
a sensor for detecting CO in the rearing chamber2Content A1、CO2Generation rate of (A)2And O2And transmitting to a processor;
a processor, the processor based on the received A1、A2And B gives the area S:
the detection unit is used for detecting the position of the animal in the feeding box and transmitting the control unit;
a control unit that adjusts the switch such that the sum of the areas of the openings at the bottom of the chamber above the location matches the area S.
The invention also aims to provide CO in the closed environment based on the control device2The purpose of the invention is realized by the following technical scheme:
CO in a closed environment according to the above-mentioned control device2The control method of (2), said control method comprising the steps of:
(A1) sensor detects CO in raising case2Content A1、CO2Generation rate of (A)2And O2And transmitting the content B to a processor, wherein the processor outputs an area S;
the detection unit detects the position of the animal in the feeding box and transmits the control unit;
(A2) the control unit adjusts the switch to enable the sum of the areas of the openings at the bottom of the chamber above the position to be matched with the area S;
(A3) the adsorbent in the opened chamber adsorbs CO in the feeding box2Thereby introducing CO into the rearing chamber2The content of (a) is reduced to a safe level.
Compared with the prior art, the invention has the beneficial effects that:
1. accurate control is realized: determining the area of the chamber to be opened (adsorbent adsorption) according to the parameters of the gas in the feeding chamber, and detecting the position of the animal (CO at the position)2High content) to open the chamber above the animal's locus to expose the adsorbent and thereby reduce CO at the animal's locus2In an amount such that it is at a safe level;
2. without using N2Remarkably reduce the costThen, the process is carried out;
3. the capacity prediction of the experimental animals in the feeding boxes with different volumes is realized.
Drawings
The disclosure of the present invention will become more readily understood with reference to the accompanying drawings. As is readily understood by those skilled in the art: these drawings are only for illustrating the technical solutions of the present invention and are not intended to limit the scope of the present invention. In the figure:
FIG. 1 is a diagram of CO in an enclosed environment according to an embodiment of the present invention2The control device of (1).
Detailed Description
Fig. 1 and the following description depict alternative embodiments of the invention to teach those skilled in the art how to make and reproduce the invention. Some conventional aspects have been simplified or omitted for the purpose of teaching the present invention. Those skilled in the art will appreciate that variations or substitutions from these embodiments will be within the scope of the invention. Those skilled in the art will appreciate that the features described below can be combined in various ways to form multiple variations of the invention. Thus, the present invention is not limited to the following alternative embodiments, but is only limited by the claims and their equivalents.
Example 1:
FIG. 1 is a schematic diagram showing CO in an enclosed environment according to example 1 of the present invention2The control device of (2) is schematically shown in FIG. 1, and CO is in the closed environment2The control device of (1) comprises:
the breeding box belongs to the prior art in the field, and the specific structure and the working mode are not described again;
a plurality of chambers disposed at the top of the feeding box; a switch is arranged on one side of the cavity adjacent to the interior of the feeding box and used for controlling the communication between the interior of the cavity and the interior of the feeding box, and CO is suitable to be placed in the cavity2An adsorbent;
a sensor for detecting CO in the rearing chamber2Content A1、CO2Generation rate of (A)2And O2And transmitting to a processor;
a processor, the processor based on the received A1、A2And B gives the area S:
The detection unit is used for detecting the position of the animal in the feeding box and transmitting the control unit;
a control unit that adjusts the switch such that the sum of the areas of the openings at the bottom of the chamber above the location matches the area S.
For the sake of uniformity, further, the chambers are arranged on the top of the breeding box in a grid shape.
In order to obtain the position of the animal in the feeding chamber in order to open the chamber above the animal accurately, further, the detecting unit employs a gravity sensing piece or a camera.
To automatically open the chamber to allow the adsorbent to adsorb CO in the feeding chamber2Further, the switch includes:
a door rotatably fixed to a bottom of the chamber;
an electronic lock for controlling whether the door and the chamber are connected or not.
CO in closed Environment of embodiments of the invention2The control method of (2), that is, the working process of the control device, the control method comprises the following steps:
(A1) sensor detects CO in raising case2Content A1、CO2Generation rate of (A)2And O2And transmitting the content B to a processor, wherein the processor outputs an area S;
the detection unit detects the position of the animal in the feeding box and transmits the control unit;
(A2) the control unit adjusts the switch to enable the sum of the areas of the openings at the bottom of the chamber above the position to be matched with the area S; matching does not mean that the sum of the areas and the area S must be equal, in view of the sum of the areas
The discreteness of (A) cannot be achieved by SnIs equal to S, but requires Sn≤S＜Sn+1；
(A3) The adsorbent in the opened chamber adsorbs CO in the feeding box2Thereby introducing CO into the rearing chamber2The content of (a) is reduced to a safe level.
In order to conveniently open the chamber, further, the switch is adjusted in a manner that:
when the control unit outputs an opening instruction, the electronic lock is opened according to the instruction, and the sealing door at the bottom of the cavity is separated from the cavity and descends under the action of gravity, so that the interior of the cavity is communicated with the interior of the feeding box.
Example 2:
CO in closed Environment according to example 1 of the invention2An application example of the control device and the method of (1).
In the application example, the opening area of each chamber is equal, and a plurality of chambers are arranged on the top of the breeding box in a grid manner; the switch adopts a door structure, the door is rotatably fixed at the bottom of the chamber, and a sealing strip is arranged between the door and the chamber; the door and the chamber are connected through the electronic lock, but when the electronic lock is opened, the door and the chamber are separated and descend under the action of gravity; the detection unit adopts a gravity sensing piece to sense the position of the animal in the feeding box.
Using animal raising box, the experimental condition is to put O in the box2Concentration was maintained at 10% in the experimentThe mice were 40 BALB/C mice. Mice in hypoxic environments appear to be quiet, immotile, and clump together.
800ppm of C and 1200ppm of D; the gravity sensing piece senses the mice close to each other, CO2Rate of rise A2At 800ppm/min, after treatment, open the area above the mouse 2280cm2Exposing the adsorbent therein.
Claims (5)
1. CO in closed environment2The control device comprises a closed feeding box; the method is characterized in that: CO in the closed environment2The control device of (1) further comprising:
the chambers are arranged at the top of the breeding box in a grid shape; a switch is arranged on one side of the cavity adjacent to the interior of the feeding box and used for controlling the communication between the interior of the cavity and the interior of the feeding box, and CO is suitable to be placed in the cavity2An adsorbent;
a sensor for detecting CO in the rearing chamber2Content A1、CO2Generation rate of (A)2And O2And transmitting to a processor;
a processor, the processor based on the received A1、A2And B gives the area S:
the detection unit is used for detecting the position of the animal in the feeding box and transmitting the control unit;
a control unit that adjusts the switch such that the sum of the areas of the openings at the bottom of the chamber above the location matches the area S.
2. An enclosed environment CO according to claim 12The control device of (2), characterized in that: the detection unit adopts a gravity sensing piece or a camera.
3. An enclosed environment CO according to claim 12The control device of (2), characterized in that: the switch includes:
a door rotatably fixed to a bottom of the chamber;
an electronic lock for controlling whether the door and the chamber are connected or not.
4. Control device according to any of claims 1 to 3, wherein the CO is present in a closed environment2The control method of (2), said control method comprising the steps of:
(A1) sensor detects CO in raising case2Content A1、CO2Generation rate of (A)2And O2And transmitting the content B to a processor, wherein the processor outputs an area S;
the detection unit detects the position of the animal in the feeding box and transmits the control unit;
(A2) the control unit adjusts the switch to enable the sum of the areas of the openings at the bottom of the chamber above the position to be matched with the area S;
(A3) the adsorbent in the opened chamber adsorbs CO in the feeding box2Thereby introducing CO into the rearing chamber2The content of (a) is reduced to a safe level.
5. An enclosed environment CO according to claim 42The control method of (2), characterized in that: the switch is adjusted in the following way:
when the control unit outputs an opening instruction, the electronic lock is opened according to the instruction, and the sealing door at the bottom of the cavity is separated from the cavity and descends under the action of gravity, so that the interior of the cavity is communicated with the interior of the feeding box.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811606017.6A CN109602516B (en) | 2018-12-26 | 2018-12-26 | CO in a closed environment2Control device and method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811606017.6A CN109602516B (en) | 2018-12-26 | 2018-12-26 | CO in a closed environment2Control device and method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109602516A CN109602516A (en) | 2019-04-12 |
| CN109602516B true CN109602516B (en) | 2021-01-01 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811606017.6A Active CN109602516B (en) | 2018-12-26 | 2018-12-26 | CO in a closed environment2Control device and method |
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105486813A (en) * | 2015-12-28 | 2016-04-13 | 华中农业大学 | Multifunctional closed small animal feeding experiment system |
| CN106413849A (en) * | 2014-05-30 | 2017-02-15 | 夏普株式会社 | Carbon dioxide concentration control device, and device |
| CN206369288U (en) * | 2016-12-31 | 2017-08-01 | 宁波华仪宁创智能科技有限公司 | The purifier of gas in closing space |
| CN107606715A (en) * | 2017-09-11 | 2018-01-19 | 太仓迭世信息科技有限公司 | A kind of subregion based on smart home removes formaldehyde air cleaning unit |
| CN207081090U (en) * | 2017-06-13 | 2018-03-09 | 南京工业大学 | Indoor carbon dioxide adsorption system suitable for ceiling type air conditioning unit |
| CN107847852A (en) * | 2015-07-27 | 2018-03-27 | 夏普株式会社 | Air-conditioning system and carbon dioxide scrubber unit |
| CN207305693U (en) * | 2017-10-25 | 2018-05-04 | 西南交通大学 | Multi-functional oxygen Bioexperiment culture storehouse |
-
2018
- 2018-12-26 CN CN201811606017.6A patent/CN109602516B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106413849A (en) * | 2014-05-30 | 2017-02-15 | 夏普株式会社 | Carbon dioxide concentration control device, and device |
| CN107847852A (en) * | 2015-07-27 | 2018-03-27 | 夏普株式会社 | Air-conditioning system and carbon dioxide scrubber unit |
| CN105486813A (en) * | 2015-12-28 | 2016-04-13 | 华中农业大学 | Multifunctional closed small animal feeding experiment system |
| CN206369288U (en) * | 2016-12-31 | 2017-08-01 | 宁波华仪宁创智能科技有限公司 | The purifier of gas in closing space |
| CN207081090U (en) * | 2017-06-13 | 2018-03-09 | 南京工业大学 | Indoor carbon dioxide adsorption system suitable for ceiling type air conditioning unit |
| CN107606715A (en) * | 2017-09-11 | 2018-01-19 | 太仓迭世信息科技有限公司 | A kind of subregion based on smart home removes formaldehyde air cleaning unit |
| CN207305693U (en) * | 2017-10-25 | 2018-05-04 | 西南交通大学 | Multi-functional oxygen Bioexperiment culture storehouse |
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| Publication number | Publication date |
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| CN109602516A (en) | 2019-04-12 |
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Address after: West side of 1st floor, 1st floor, Building A, No. 288 Jingu Middle Road (East), Yinzhou District, Ningbo City, Zhejiang Province, 315000 Patentee after: CHINA INNOVATION INSTRUMENT Co.,Ltd. Country or region after: China Patentee after: Ningbo University Address before: Room 304, D Building, Kexin Building, 655 Xueshi Road, Yinzhou District, Ningbo City, Zhejiang Province, 315000 Patentee before: CHINA INNOVATION INSTRUMENT Co.,Ltd. Country or region before: China Patentee before: Ningbo University |