CN104855690A - Compound feed for grown pigs and preparation method of compound feed - Google Patents
Compound feed for grown pigs and preparation method of compound feed Download PDFInfo
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Abstract
The invention discloses a compound feed for grown pigs and a preparation method of the compound feed. The feed comprises the following raw materials: cooked millet, rapeseed dregs, dried cucumber powder, kale, salt, choline chloride, corn oil, vitamin premix, trace element premix and traditional Chinese medicine additives. The compound feed disclosed by the invention has the beneficial effects that the traditional Chinese medicine additives contained in the feed have the main effects of clearing away heat, relieving exterior syndromes, clearing qi and cooling blood and also has the auxiliary effects of cooling blood, activating blood circulation, promoting urination, invigorating stomach and tonifying spleen and tonifying middle-Jiao and Qi and are matched with other feed raw materials to realize the combined action, and the feed is used for treating high swine fever, has the advantages of good treatment effect, high cure rate, fast effectiveness, low cost and the like and does not have any toxic or side effect. Moreover, the added traditional Chinese medicine additives can be used for achieving the effect of preventing the high swine fever.
Description
Technical field
The present invention relates to animal feed, particularly a kind of bred pigs mixed feed being used for the treatment of porcine hyperthermia and preparation method thereof.
Background technology
Porcine hyperthermia is the disease that a kind of M & M is all higher, and the clinical main manifestations of sick pig is that body temperature raises, spirit is depressed, poor appetite or absolutely useless, and have difficulty in breathing, breathe, part pig is with symptoms such as rubefaction purplings, and minority pore has blutpunkte.Cause of disease is mainly multiple virus and bacterium, parasitic mixed infection and scabies secondary infection, comprise CSFV (HCV), porcine reproductive and respiratory syndrome virus (PRRSV), swine influenza virus (SIV), pseudorabies virus (ADV), porcine circovirus 2 type (PCV-II) and actinobacillus pleuropneumoniae (APP), Streptococcus suis belongs to 2 types (SS-II), Haemophilus parasuis (HP), pasteurella multocida (PM), porcine mycoplasmal pneumonia (MH), toxoplasm, eperythrozoon, the mixed infection of the bacteriums such as Salmonella choleraesuls (SC).
Clinical symptoms show as unexpected onset, and chilly flocks together, and morbidity temperature of pig body is increased to 40 ~ 42.5 DEG C, spirit is depressed, and feed intake declines or appetite is given up absolutely, affected pig rubefaction, after ear in one's ear under edge cyanosis, abdomen and the health many places skin such as four limbs tip have patch shape, in aubergine; Expiratory dyspnea, happiness is lain prostrate, and serious abdominal respiration appears in part pig, and asthma is rapid, and some performances are breathed or are irregular breathing; Part affected pig is had a running nose, sneeze, cough, discharge of eye increases, and most of pig has tear spot, occurs conjunctivitis symptoms; The constipation of part swinery, ight soil is constipated, in spherical, urine yellow and less, muddy, color burn.The sick pig whole body that the course of disease is slightly long is pale, occurs anaemia phenomenon, and by hair slightly disorderly, the sick pig hind limb weakness of part, can not stand before indivedual sick pig is dying, and last whole body is twitched and dead.The morbidity swinery death rate is very high, and some pig farms are even up to 50 ~ 90%.There is miscarriage in later stage of pregnancy (100 ~ 110 days) in part sow, produces stillborn foetus, weak son and mummy.
All there is pneumonia in various degree in all sick dead pig, cuts open the visible following symptom of inspection: 1. lung swelling, hardening; In not shrinkable rubber shape lung, interstitial pneumonia symptom is obvious, and lung presents mottling to brown pathology (marble sample); Great majority are all mixed infection pneumonia, have suppuration stove, part pig empsyxis, and hemorrhagic pneumonia, interstitial is obviously broadening.2. lymph node extensive enlargement, particularly inguinal lymph nodes and hilar lymph node.3. the sick dead pig liver swelling had, color is thin out, and some livers are then in loess look, and matter is crisp, and indivedual pig kidney, bladder, larynx, sulcus coronarius fat and intracardiac adventitia etc. have blutpunkte; The enlargement of part sick dead pig kidney, darkens, and in brown or khaki, quality is more crisp, has hemostasis phenomenon.The sick pig spleen enlargement had, matter is crisp.4. multiple serofibrinous pleurisy and peritonitis, there is fibrinous oozing out in thoracic cavity and abdominal cavity.Indivedual pig lung serous coat and pleura or the adhesion of pericardium cellulosic.
At present, treatment generally use Western medicine to treat, as 20% Florfenicol 100g+ astragalus polyose powder 200g+ swap buffers powder 100g mix fodder 400kg treats, or preparation uses the biological products such as interferon to treat, but general curative effect is not high, cure rate is low, and cost is also higher.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine additive being used for the treatment of porcine hyperthermia, have that result for the treatment of is good, cure rate is high, instant effect, have no side effect, the advantage such as cost is low, and Chinese medicine additive of the present invention can also play the effect of preventing swine high fever.
In order to realize foregoing invention object, the invention provides a kind of bred pigs mixed feed, described feed comprises following raw material: the millet boiled, rapeseed dregs, cucumber dry powder, Brussels sprouts, salt, Choline Chloride, corn oil, vitamin premix, microelement pre-mix material and Chinese medicine additive.
Described feed is made up of the raw material of following parts by weight: millet 40-70 weight portion, rapeseed dregs 23-45 weight portion, cucumber dry powder 20-35 weight portion, Brussels sprouts 10-20 weight portion, salt 1-2 weight portion, Choline Chloride 1-2 weight portion, corn oil 1-4 weight portion, vitamin premix 0.01-0.03 weight portion, microelement pre-mix material 0.01-0.03 weight portion and Chinese medicine additive 2-7 weight portion.
Described feed is made up of the raw material of following parts by weight: millet 56 weight portion, rapeseed dregs 34 weight portion, cucumber dry powder 27 weight portion, Brussels sprouts 15 weight portion, salt 2 weight portion, Choline Chloride 1 weight portion, corn oil 3 weight portion, vitamin premix 0.01 weight portion, microelement pre-mix material 0.01 weight portion and Chinese medicine additive 4 weight portion.
Described Chinese medicine additive comprises following raw medicinal material: fourth grass in the last of the ten Heavenly stems, German tamarisk, hooker winghead root, bastard indigo, arabian jasmine leaf, Japanese Raspberry Root, the capsule of weeping forsythia, the radix paeoniae rubrathe, almond, Asian puccoon, ilex pubescens, waterlettuce herb, arrowhead and Radix Glycyrrhizae.
Described Chinese medicine additive is made up of the raw medicinal material of following parts by weight: fourth grass in last of the ten Heavenly stems 20-35 weight portion, German tamarisk 17-31 weight portion, hooker winghead root 5-10 weight portion, bastard indigo 4-9 weight portion, arabian jasmine leaf 10-25 weight portion, Japanese Raspberry Root 10-15 weight portion, capsule of weeping forsythia 7-15 weight portion, radix paeoniae rubrathe 20-35 weight portion, almond 5-11 weight portion, Asian puccoon 10-20 weight portion, ilex pubescens 20-35 weight portion, waterlettuce herb 10-18 weight portion, arrowhead 15-25 weight portion and Radix Glycyrrhizae 20-30 weight portion.
Described Chinese medicine additive is made up of the raw medicinal material of following parts by weight: fourth grass in the last of the ten Heavenly stems 27 weight portions, German tamarisk 23 weight portion, hooker winghead root 6 weight portion, bastard indigo 6 weight portion, arabian jasmine leaf 17 weight portion, Japanese Raspberry Root 12 weight portion, the capsule of weeping forsythia 10 weight portion, the radix paeoniae rubrathe 26 weight portion, almond 7 weight portion, Asian puccoon 15 weight portion, ilex pubescens 27 weight portion, waterlettuce herb 14 weight portion, arrowhead 20 weight portion and Radix Glycyrrhizae 24 weight portion.
Described Chinese medicine additive also comprises Scirpus tabernaemontani, cassia twig, forestry greenstar root, rhizome of Scopulosus Bergenia, polished rice and pigeonpea, described Chinese medicine additive is made up of the raw medicinal material of following parts by weight: fourth grass in last of the ten Heavenly stems 20-35 weight portion, German tamarisk 17-31 weight portion, hooker winghead root 5-10 weight portion, bastard indigo 4-9 weight portion, arabian jasmine leaf 10-25 weight portion, Japanese Raspberry Root 10-15 weight portion, capsule of weeping forsythia 7-15 weight portion, radix paeoniae rubrathe 20-35 weight portion, almond 5-11 weight portion, Asian puccoon 10-20 weight portion, ilex pubescens 20-35 weight portion, waterlettuce herb 10-18 weight portion, arrowhead 15-25 weight portion, Radix Glycyrrhizae 20-30 weight portion, Scirpus tabernaemontani 15-28 weight portion, cassia twig 10-15 weight portion, forestry greenstar root 10-15 weight portion, rhizome of Scopulosus Bergenia 5-12 weight portion, polished rice 10-22 weight portion and pigeonpea 10-15 weight portion.
Described Chinese medicine additive is made up of the raw medicinal material of following parts by weight: fourth grass in the last of the ten Heavenly stems 27 weight portions, German tamarisk 23 weight portion, hooker winghead root 6 weight portion, bastard indigo 6 weight portion, arabian jasmine leaf 17 weight portion, Japanese Raspberry Root 12 weight portion, the capsule of weeping forsythia 10 weight portion, the radix paeoniae rubrathe 26 weight portion, almond 7 weight portion, Asian puccoon 15 weight portion, ilex pubescens 27 weight portion, waterlettuce herb 14 weight portion, arrowhead 20 weight portion, Radix Glycyrrhizae 24 weight portion Scirpus tabernaemontani 21 weight portion, cassia twig 12 weight portion, forestry greenstar root 13 weight portion, rhizome of Scopulosus Bergenia 7 weight portion, polished rice 16 weight portion and pigeonpea 12 weight portion.
The preparation method of described Chinese medicine additive is:
The first step, mixes in proportion by each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, adds hot reflux 1 ~ 3 hour, extracts, and filters acquisition first extract; Filter the dregs of a decoction obtained to add relative to the determining alcohol of described dregs of a decoction quality 1 ~ 2 times to be again the ethanol of 85 ~ 95%, to add hot reflux 1 ~ 3 hour that acquisition second extract is filtered in extraction; First extract and the second extract are merged, reduced pressure concentration removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in micronizer and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;
3rd step, adds the starch relative to its quality 2 ~ 4 times in the micropowders obtained by second step, mixing, obtains powder.
In order to better realize foregoing invention object, the invention provides a kind of preparation method of bred pigs mixed feed, described preparation method is:
Pulverising step: take the millet, rapeseed dregs and the Brussels sprouts that boil by weight, drops into pulverizer and pulverizes;
Blend step: by weight by after cucumber dry powder, salt, Choline Chloride, corn oil, vitamin premix, microelement pre-mix material and Chinese medicine additive premixed, more fully mix with the comminuting matter obtained in pulverising step;
Granulation step: drop into granulator, granulates, makes its gelatinization degree reach 90% at 70-80 DEG C.
The invention has the beneficial effects as follows: the Chinese medicine additive that feed of the present invention contains is based on relieving superficies by cooling, clearing both qifen and yingfen, be auxiliary with cooling and activating blood, tonneau urine, stomach invigorating tonifying spleen, tonifying middle-Jiao and Qi, cooperatively interact with other feedstuffs, acting in conjunction, treatment porcine hyperthermia has that result for the treatment of is good, cure rate is high, instant effect, have no side effect, the advantage such as cost is low, and Chinese medicine additive of the present invention can also play the effect of preventing swine high fever; Wherein, feed of the present invention selects the raw material of absorption easy to digest to prepare, and strengthens functions of intestines and stomach, and the state of an illness accelerating ill pig is recovered.
Detailed description of the invention
The soul of Chinese veterinarian be because of time, because of the dialectical treatment on ground, porcine hyperthermia has infectiousness, popularity, belongs to pestilence category in Chinese veterinarian, specifically distinguish control time dialectical based on defensive-qi-nutrient-blood, be aided with the analysing and differentiating of febrile disease in accordance with the theory of the six pair of channels, two method R. concomitans are more appropriate.Porcine hyperthermia changes rapidly, and according to clinical symptoms and multinomial concrete case, be substantially in ill mid-term when mostly finding ill, namely flush appears in skin, is short of breath, and high heat is hard to bear, not for symptoms such as food.The invention provides a kind of Chinese medicine additive being used for the treatment of porcine hyperthermia, be specially adapted to the ill pig in porcine hyperthermia mid-term, Chinese medicine additive comprises following raw medicinal material: fourth grass in the last of the ten Heavenly stems, German tamarisk, hooker winghead root, bastard indigo, arabian jasmine leaf, Japanese Raspberry Root, the capsule of weeping forsythia, the radix paeoniae rubrathe, almond, Asian puccoon, ilex pubescens, waterlettuce herb, arrowhead and Radix Glycyrrhizae; Preferably also comprise Scirpus tabernaemontani, cassia twig, forestry greenstar root, rhizome of Scopulosus Bergenia, polished rice and pigeonpea.Wherein, fourth grass in the last of the ten Heavenly stems is clearing heat and detoxicating, German tamarisk inducing diaphoresis to dispel wind, hooker winghead root relieving superficies by cooling, clear away heart-fire cool blood, bastard indigo invigorating the spleen to dry, the capsule of weeping forsythia is warm joins the army, clearing heat and detoxicating, radix paeoniae rubrathe clearing heat and cooling blood, almond clearing both qifen and yingfen, be monarch drug in a prescription altogether, Asian puccoon, ilex pubescens, waterlettuce herb, arrowhead cooling and activating blood, arabian jasmine leaf, Japanese Raspberry Root relieving superficies by cooling, be ministerial drug altogether, play relieving superficies by cooling altogether, effect of cooling and activating blood, the waterlettuce herb added, arrowhead, Scirpus tabernaemontani, cassia twig tonneau urine, bastard indigo, forestry greenstar root, rhizome of Scopulosus Bergenia, stalk rice stomach invigorating tonifying spleen, polished rice, pigeonpea tonifying middle-Jiao and Qi, Radix Glycyrrhizae Qi-benefiting and heart-nourishing, coordinating the drug actions of a prescription, for adjuvant, full side organically combines, complement each other, play relieving superficies by cooling altogether, the effect of clearing both qifen and yingfen.
The pharmacological property of above-mentioned each raw medicinal material is as follows:
Fourth grass in the last of the ten Heavenly stems: sweet, light, cool.Function cures mainly: clearing heat and detoxicating, removing pattogenic heat from the blood and toxic material from the body.For flu, sphagitis, acute icteric hepatitis, acute gastroenteritis, acute appendicitis, infantile malnutrition, acute mastitis, eye keratitis; Traumatic injury is controlled in external application, carbuncle furuncle poison, venomous snake bite.
German tamarisk: taste is pungent; Sweet; Slightly warm in nature.Function cures mainly: promoting eruption of inducing sweat; Dispelling wind and arresting itching.Main measles without adequate eruption; Arthralgia due to wind-dampness; Ringworm.
Hooker winghead root: bitter, cold.Function cures mainly: relieving superficies by cooling, and clear away heart-fire cool blood.For the fever that cold, fever and various warm heat disease cause, dysphoria with smothery sensation in the heart, hemoptysis, spit blood, hematuria, has blood in stool.
Bastard indigo: micro-hardship, flat.Function cures mainly: induce sweat, invigorating the spleen to dry, promoting qi circulation and relieving pain.For anemopyretic cold, indigestion, abdominal distension is suffered from abdominal pain, chronic gastritis; Eczema is controlled in external application, dermatitis.
Arabian jasmine leaf: pungent; Micro-hardship; Warm in nature.Return lung; Stomach warp.Function cures mainly: expelling wind to resolve the exterior; Swelling and pain relieving.Main fever caused by exogenous pathogens; Rush down dysentery abdominal distension; Beriberi swells and ache; Insect bite.
Japanese Raspberry Root: another name: Mao daughter dish (" interrogating book on Chinese herbal medicine "), clear and bright grass (" classifying herbal "), spire affine cudweed (" botany voluminous dictionary "), Fu Zicao; Little ground arhat, leaflet golden pheasant tongue, Bai Zhaoqu (" Fujian traditional herbal medicine "), little fire weed (" Traditional Chinese Medicine in Sichuan will "), wild clear and bright grass (" Chongqing herbal medicine "), hair water ant, Thunder God green grass or young crops, pineapple careless (" Hunan medicine will "), white under leaf, golden pheasant tongue, white careless son, little Bai Genju (" east, Fujian book on Chinese herbal medicine "), black clouds lid snow, cotton grass (" Fujian Chinese herbal medicine ").Source is the herb of feverfew Japan affine cudweed.Gather after spending, dry.Perennial herb is high 8 ~ 25 centimetres during flower.Stem is very thin, most, grows thickly, adularescent wool.Base portion leaf is rosette-stape, and wire falls lanceolar, and long 2.5 ~ 10 centimetres, wide 4 ~ 7 millimeters, tip is blunt, tool tip, and base portion is carefully narrow, Quan Yuan, does not fall after spending, above green or slightly white wool, below adularescent fine hair; Stem's leaf is short and small gradually, linear, long 2 ~ 2.5 centimetres, wide 2 ~ 4 millimeters.Capitulum is most, clusters in top; Bract 3 arranges, burgundy, and outer row bract is oval, interior row bract narrow oblong; Be all tubular flower, brownish red, is about 3.5 millimeters; Peripheral ordered series of numbers, female, corolla is narrow in line; Central authorities' ordered series of numbers is hermaphrodite flower, and corolla is elongated, and tip 5 splits; Stamen 5, synandrium, flower pesticide base portion flechette-type; Gynoecium 1, column cap 2 splits.Achene is oval, is about 1 millimeter, has choice refreshments; Pappus 1 arranges, and very thin rent is rough.4 ~ May of florescence.Habitats distribution: be born in wasteland, roadside, Tian Bian, border.Distribution East China, southwestern various places.Sweet, cool.Function cures mainly: induce sweat, heat-clearing, improving eyesight, diuresis.Cure cold, cough, headache, laryngalgia, cataract, urine heat is closed, stranguria with turbid discharge, leukorrhea, and carbuncle swells, furunculosis.
The capsule of weeping forsythia: bitter, is slightly cold.Return lung, the heart, small intestinl channel.Function cures mainly: clearing heat and detoxicating, dispersing swelling and dissipating binds.For ulcer, scrofula, acute mastitis, erysipelas, anemopyretic cold, warm disease from the beginning of, warmly join the army, high hot polydipsia, coma sends out spot, and heat drenches renal shutdown.
The radix paeoniae rubrathe: bitter, is slightly cold.Return Liver Channel.Function cures mainly: clearing heat and cooling blood, blood stasis removing analgesic.For febrile virulent maculae, hematemesis and epistaxis, red eye, swell pain, liver-depressed hypochondrium pain, through closing dysmenorrhoea, abdominal mass is suffered from abdominal pain, injury from falling down, and carbuncle swells sore.
Almond: bitter; Temperature.Return lung; Spleen; Large intestine channel.Function cures mainly: expelling phlegm and arresting coughing; Relieving asthma; Ease constipation; Lower gas opens numbness.Main exogenous cough; Breathe heavily full; Cough due to dryness; Cold air is to globefish; Frightened epilepsy; The obstruction of qi in the chest; Dyspeptic stomachache; Metrorrhagia; Deaf; Malnutritional scrotal edema; Damp-heat gonorrhoea; Scabies; Larynx numbness; The dry constipation of intestines.
Asian puccoon: sweet, salty, cold.The thoughts of returning home, Liver Channel.Function cures mainly: cool blood, invigorates blood circulation, removing toxic substances promoting eruption.Contain for blood-head poison, macula purple is black, measles without adequate eruption, sore, eczema, scald.
Ilex pubescens: bitter, flat.Function cures mainly: blood circulation and channel invigorating, and swelling and pain relieving is clearing heat and detoxicating.For angina pectoris, myocardial infarction, Buerger's disease, central retinitis, tonsillitis, sphagitis, infantile pneumonia, pernio.
Waterlettuce herb: taste is pungent; Cold in nature.Return lung; Spleen; Liver Channel.Function cures mainly: dispelling mild wind and promoting eruption; Promoting urination and removing dampness; Cooling and activating blood.Main anemopyretic cold; Single board computer rash is not saturating; Nettle rash; Blood-head itch; Juice spot; Eczema; Oedema; Difficult urination; Arthralgia due to wind-dampness; Ulcer on the shank; Erysipelas; Nameless sores or boils; Treating swelling and pain by traumatic injury.
Arrowhead: taste is sweet; Micro-hardship; Micro-pungent; Cold nature.Return liver; Lung; Spleen; Urinary bladder channel.Function cures mainly: promoting blood circulation and cooling blood; Cough-relieving is treating stranguria; Powder detoxifcation.After main product, blood is vexed; Retention of afterbirth; Under band; Uterine bleeding; Bleeding from five sense organs or subcutaneous tissue; Spitting blood; Cough phlegm blood; Stranguria with turbid discharge; Sore swells; Red eye, swell pain; Keratoleukoma; Scrofula; Orchitis; Periostitis; Poisonous snake flood dragon hinders.
Radix Glycyrrhizae: sweet, flat.The thoughts of returning home, lung, spleen, stomach warp.Function cures mainly: invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, the anxious pain of gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Scirpus tabernaemontani: taste is sweet; Light; Property is put down.Return urinary bladder channel.Function cures mainly: inducing diuresis for removing edema.Main oedema turgor; Difficult urination.
Cassia twig: acrid, sweet, warm.The thoughts of returning home, lung, urinary bladder channel.Function cures mainly: sweating expelling pathogenic factors from muscles and skin, and warming meridian, helps yang transforming qi, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, blood is cold through closing, and joint pain, phlegm and retained fluid, oedema, palpitaition, to globefish.
Forestry greenstar root: sweet is flat.Function cures mainly: tonifying spleen stomach invigorating, invigorates the kidney and stops nocturnal emission.Cure mainly chronic gastritis, poor appetite, weakness of limbs, seminal emission.
Rhizome of Scopulosus Bergenia: another name: stone Chinese cabbage, Chinese cabbage.Source: be the rhizome of saxifragaceae plant Qinling Mountains purple bergenia herb.The whole year can adopt.Remove fibrous root, dry use.Original shape state: perennial herb, high 5 ~ 50 centimetres, all level and smooth without hair, rhizome is sturdy, crawls, cylindrical.Phyllopodium is raw, tool handle, and nearly meat is glossy, and circular or wide ovum shape is circular, long 5 ~ 35 centimetres, wide 3 ~ 30 centimetres, and base portion subcircular or even wedge shape slightly, edge tool cognate or not obvious tooth, a few entire leaf veinclearing shows.Coniform cyme top is raw, tool majority flower; Petal 5, pale red; Stamen 10; Gynobase 2 Room, Room, top 1, ovule is most, and capsule 2 lobe splits.Habitats distribution: be born on moistening cliff.The ground such as distribution Shaanxi.The micro-hardship of puckery, property is put down.Function cures mainly: tonifying spleen stomach invigorating, and the solid intestines of inducing astrigency, dehumidifying Li Shui, invigorates blood circulation.Treating acute and chronic enterogastritis, edema, uterine bleeding, leukorrhea, stranguria, dysentery, impetigo, the favus of the scalp, mange.
Polished rice: sweet; Flat.Return spleen; Stomach; Lung channel.Function cures mainly: air making-up and spleen enlivening; Relieving thirst and restlessness; Antidiarrheal dysentery.Main deficiency of spleen-QI and stomach-QI; Food is few indigestion and loss of appetite; Lassitude hypodynamia; Restlessness and thirst; Rush down lower dysentery.
Pigeonpea: pungent, puckery; Flat.Return liver; The spleen channel.Function cures mainly: dampness removing, detumescence, the loose stasis of blood, hemostasis.Main air pain of dampness syndrome, traumatic injury, bleeding from five sense organs or subcutaneous tissue, has blood in stool, sore furuncle poison, prolonged lochia, oedema, icteric hepatitis.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.
Embodiment 1 powder
Embodiments provide a kind of Chinese medicine additive being used for the treatment of porcine hyperthermia, be made up of the raw medicinal material of following parts by weight: fourth grass in the last of the ten Heavenly stems 27 weight portions, German tamarisk 23 weight portion, hooker winghead root 6 weight portion, bastard indigo 6 weight portion, arabian jasmine leaf 17 weight portion, Japanese Raspberry Root 12 weight portion, the capsule of weeping forsythia 10 weight portion, the radix paeoniae rubrathe 26 weight portion, almond 7 weight portion, Asian puccoon 15 weight portion, ilex pubescens 27 weight portion, waterlettuce herb 14 weight portion, arrowhead 20 weight portion and Radix Glycyrrhizae 24 weight portion;
Its preparation method is:
The first step, mixes in proportion by each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 3 times is the ethanol of 90%, adds hot reflux 2 hours, extracts, and filters acquisition first extract; Filter the dregs of a decoction obtained to add relative to the determining alcohol of described dregs of a decoction quality 2 times to be again the ethanol of 90%, to add hot reflux 2 hours that acquisition second extract is filtered in extraction; First extract and the second extract are merged, reduced pressure concentration removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in micronizer and pulverizes 1.5 hours, pulverize, sieve, obtain 400 object micropowders;
3rd step, adds the starch relative to its quality 3 times in the micropowders obtained by second step, mixing, obtains powder.
Embodiment 2 feed
Embodiments provide a kind of bred pigs mixed feed, be made up of the raw material of following parts by weight: millet 56 weight portion, rapeseed dregs 34 weight portion, cucumber dry powder 27 weight portion, Brussels sprouts 15 weight portion, salt 2 weight portion, Choline Chloride 1 weight portion, corn oil 3 weight portion, vitamin premix 0.01 weight portion, microelement pre-mix material 0.01 weight portion and Chinese medicine additive 4 weight portion;
Wherein, cucumber dry powder is obtain after the air-dry rear pulverizing of cucumber, Chinese medicine additive is made up of the raw medicinal material of following parts by weight: fourth grass in the last of the ten Heavenly stems 27 weight portions, German tamarisk 23 weight portion, hooker winghead root 6 weight portion, bastard indigo 6 weight portion, arabian jasmine leaf 17 weight portion, Japanese Raspberry Root 12 weight portion, the capsule of weeping forsythia 10 weight portion, the radix paeoniae rubrathe 26 weight portion, almond 7 weight portion, Asian puccoon 15 weight portion, ilex pubescens 27 weight portion, waterlettuce herb 14 weight portion, arrowhead 20 weight portion, Radix Glycyrrhizae 24 weight portion Scirpus tabernaemontani 21 weight portion, cassia twig 12 weight portion, forestry greenstar root 13 weight portion, rhizome of Scopulosus Bergenia 7 weight portion, polished rice 16 weight portion and pigeonpea 12 weight portion,
The preparation method of Chinese medicine additive is:
The first step, mixes in proportion by each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 3 times is the ethanol of 90%, adds hot reflux 2 hours, extracts, and filters acquisition first extract; Filter the dregs of a decoction obtained to add relative to the determining alcohol of described dregs of a decoction quality 2 times to be again the ethanol of 90%, to add hot reflux 2 hours that acquisition second extract is filtered in extraction; First extract and the second extract are merged, reduced pressure concentration removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in micronizer and pulverizes 1.5 hours, pulverize, sieve, obtain 400 object micropowders;
3rd step, adds the starch relative to its quality 3 times in the micropowders obtained by second step, mixing, obtains powder.
The preparation method of feed is:
Pulverising step: take the millet, rapeseed dregs and the Brussels sprouts that boil by weight, drops into pulverizer and pulverizes;
Blend step: by weight by after cucumber dry powder, salt, Choline Chloride, corn oil, vitamin premix, microelement pre-mix material and Chinese medicine additive premixed, more fully mix with the comminuting matter obtained in pulverising step;
Granulation step: drop into granulator, granulates, makes its gelatinization degree reach 90% at 75 DEG C.
Toxicity test
By fourth grass in last of the ten Heavenly stems 27g, German tamarisk 23g, hooker winghead root 6g, bastard indigo 6g, arabian jasmine leaf 17g, Japanese Raspberry Root 12g, capsule of weeping forsythia 10g, radix paeoniae rubrathe 26g, almond 7g, Asian puccoon 15g, ilex pubescens 27g, waterlettuce herb 14g, arrowhead 20g, Radix Glycyrrhizae 24g, Scirpus tabernaemontani 21g, cassia twig 12g, forestry greenstar root 13g, rhizome of Scopulosus Bergenia 7g, polished rice 16g and pigeonpea 12g mixes, be ground into 200 object powder, add the water of 1575g, soak after 30 minutes, decoct 1 hour at the temperature of 100 DEG C, decoction liquor is filtered, obtain the first filtered fluid and filter residue, the filter residue of acquisition is added the water of 1300g, at the temperature of 100 DEG C, decoct 50 minutes, decoction liquor is filtered, obtain the second filtered fluid, first filtered fluid and the second filtered fluid are merged, obtain decoction liquor 1.
Select SD rat 60, divide three groups, often organize 20, give the decocting liquid 1 of the Chinese medicine composition of the present invention of variable concentrations (18.0,6.0,2.0g crude drug/kg), every day gavage once, continuous 90 days, within after last administration 24 hours, respectively group is alive killed 1/2 animal (male and female half and half), and all the other 1/2 animals continue observations 2 weeks rear living and kill.Duration of test observes outward appearance, general behavior, food ration, the changes of weight of animal, within after administration 90 days, within 2 weeks, carries out the index checking such as hematology (RBC, HB, granulophilocyte, PLT, CT, WBC and classification) and blood biochemical (AST, ALT, ALP, Glu, BUN, Crca, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, Histopathology with drug withdrawal.Result of the test shows: Chinese medicine preparation of the present invention is good at high, medium and low dosage treated animal general state, and outward appearance sign, behavioral activity, food-intake and body weight increase change all without exception; Three dosage groups and control group hematological examination, blood biochemical analysis, urine biochemical analysis all in normal range (NR), without significant difference between group; Each group of main organs histopathological examination shows no obvious abnormalities.These parameters drug withdrawal also had no change after 2 weeks.This test dosage is respectively 180,60,20 times of clinical medicine dose, rat is had no significant effect in high, medium and low three dosage (18.0,6.0,2.0g crude drug/kg) administration in continuous 90 days according to result of the test Chinese medicine preparation of the present invention, without clear and definite toxicity target organ and sensitive indicator, convalescence observation also has no retardance toxic reaction, points out the dose safety of Chinese medicine preparation clinical practice of the present invention higher.
Contrast test
One, Experiment on therapy:
Porcine hyperthermia is broken out in by the end of July, 2013 in pig farm, Shandong, especially to grow bred pigs for principal pathogenetic group, show spiritual depressed, feed intake decline, during beginning, find that indivedual pig is had a fever, raiser does not take notice of very much, also do not take any remedy measures, find after one week that fever appears in most of swinery, body temperature rises to more than 39 DEG C, indivedual pig occurs dead, be found to be apostematosa pneumonia through dissecting, most of pig body skin has patch shape, in aubergine.The gestational period there is the phenomenon of accidental abortion in sow.Be defined as porcine hyperthermia after diagnosing.Ill pig about 20 week age of wherein making a definite diagnosis has about 320.Ill piglet about 160 20 week ages of random selecting, be divided into two groups, each group of ill pig is at all no significant differences such as body weight, the state of an illness, be respectively embodiment group and control group, the feed of the embodiment of the present invention 2 and conventional medicament is used to treat respectively, the feed traditionally feed mode nursing of embodiment 2, if the ill pig of useless food, can be mixed into the feed of embodiment 2 after pasty state made by drinking water and gavage; Conventional medicament selects 20% Florfenicol 100g+ astragalus polyose powder 200g+ swap buffers powder 100g mix fodder 400kg to treat, continuously treatment 7 days.Treatment results is as shown in table 1.Wherein, after medication, swinery mental status, appetite all recover normal, and apnea difficulty waits systemic symptom, and temperature recovery is normally recovery from illness; Swinery spirit after medication, appetite takes a turn for the better to some extent, and still have dyspneic phenomenon, body temperature declines to some extent, and for effectively, after medication, spirit, appetite have not yet to see improvement, and breathe suffering for alleviating, even have and increase the weight of trend, body temperature does not fall, for invalid.
Table 1 each experimental group result for the treatment of table of comparisons only
| Group | Sum | Recovery from illness | Effectively | Invalid | Cure rate |
| Embodiment group | 60 | 57 | 2 | 1 | 95.0% |
| Control group | 60 | 30 | 16 | 14 | 50.0% |
As can be seen from the data of table 1, the feed of the embodiment of the present invention 2 treatment porcine hyperthermia is used to have advantage that is effective, that have no side effect.
Two, prevention experiment:
In by the end of July, 2013, all are normal for pig farm, Shandong pig, choose bred pigs about 200 healthy 20 week ages as experimental subjects, be divided into two groups at random, be respectively prevention group and treatment group, use respectively and feed 7 days containing the feed of the embodiment of the present invention 2 and conventional feed, the ill pig afterwards 10 being suffered from hyperpyrexia disease is mixed into the swinery 15 days of two experimental group respectively, period continuation is fed in the manner described above, the incidence of disease during record.Result is as shown in table 2.
Table 2 each experimental group prevention result table of comparisons only
| Group | Sum | Morbidity number | The incidence of disease |
| Prevention group | 100 | 5 | 5% |
| Control group | 100 | 79 | 79% |
As can be seen from the data of table 2, the feed of the embodiment of the present invention 2 is used to have the effect of prevention hyperpyrexia disease, and Be very effective.
Model case
Certain self-employed worker that raises pigs finds that 23 bred pigs of feeding all occur that Gao Reda 40 DEG C, appetite are useless absolutely, skin is blue, expiratory dyspnea in August, 2014, there is difficult defecation in some; the phenomenon of urine jaundice; and there is dead pig; pig is dissected; find pulmonary edema, in diffuse interstitial pneumonia, lung swelling.Be diagnosed as porcine hyperthermia, select wherein 10 ill pigs, use the feed of the embodiment of the present invention 2 to treat, continuous 6 days, treat the 4th day 10 ill pigs and substantially recover normal, continual cure 2 days, all fully recovered.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. a bred pigs mixed feed, is characterized in that, described feed comprises following raw material: the millet boiled, rapeseed dregs, cucumber dry powder, Brussels sprouts, salt, Choline Chloride, corn oil, vitamin premix, microelement pre-mix material and Chinese medicine additive.
2. bred pigs mixed feed according to claim 1, it is characterized in that, described feed is made up of the raw material of following parts by weight: millet 40-70 weight portion, rapeseed dregs 23-45 weight portion, cucumber dry powder 20-35 weight portion, Brussels sprouts 10-20 weight portion, salt 1-2 weight portion, Choline Chloride 1-2 weight portion, corn oil 1-4 weight portion, vitamin premix 0.01-0.03 weight portion, microelement pre-mix material 0.01-0.03 weight portion and Chinese medicine additive 2-7 weight portion.
3. bred pigs mixed feed according to claim 1 and 2, it is characterized in that, described feed is made up of the raw material of following parts by weight: millet 56 weight portion, rapeseed dregs 34 weight portion, cucumber dry powder 27 weight portion, Brussels sprouts 15 weight portion, salt 2 weight portion, Choline Chloride 1 weight portion, corn oil 3 weight portion, vitamin premix 0.01 weight portion, microelement pre-mix material 0.01 weight portion and Chinese medicine additive 4 weight portion.
4. the bred pigs mixed feed according to any one of claim 1-3, it is characterized in that, described Chinese medicine additive comprises following raw medicinal material: fourth grass in the last of the ten Heavenly stems, German tamarisk, hooker winghead root, bastard indigo, arabian jasmine leaf, Japanese Raspberry Root, the capsule of weeping forsythia, the radix paeoniae rubrathe, almond, Asian puccoon, ilex pubescens, waterlettuce herb, arrowhead and Radix Glycyrrhizae.
5. the bred pigs mixed feed according to any one of claim 1-4, it is characterized in that, described Chinese medicine additive is made up of the raw medicinal material of following parts by weight: fourth grass in last of the ten Heavenly stems 20-35 weight portion, German tamarisk 17-31 weight portion, hooker winghead root 5-10 weight portion, bastard indigo 4-9 weight portion, arabian jasmine leaf 10-25 weight portion, Japanese Raspberry Root 10-15 weight portion, capsule of weeping forsythia 7-15 weight portion, radix paeoniae rubrathe 20-35 weight portion, almond 5-11 weight portion, Asian puccoon 10-20 weight portion, ilex pubescens 20-35 weight portion, waterlettuce herb 10-18 weight portion, arrowhead 15-25 weight portion and Radix Glycyrrhizae 20-30 weight portion.
6. the bred pigs mixed feed according to any one of claim 1-5, it is characterized in that, it is characterized in that, described Chinese medicine additive is made up of the raw medicinal material of following parts by weight: fourth grass in the last of the ten Heavenly stems 27 weight portions, German tamarisk 23 weight portion, hooker winghead root 6 weight portion, bastard indigo 6 weight portion, arabian jasmine leaf 17 weight portion, Japanese Raspberry Root 12 weight portion, the capsule of weeping forsythia 10 weight portion, the radix paeoniae rubrathe 26 weight portion, almond 7 weight portion, Asian puccoon 15 weight portion, ilex pubescens 27 weight portion, waterlettuce herb 14 weight portion, arrowhead 20 weight portion and Radix Glycyrrhizae 24 weight portion.
7. the bred pigs mixed feed according to any one of claim 1-6, is characterized in that, described Chinese medicine additive also comprises Scirpus tabernaemontani, cassia twig, forestry greenstar root, rhizome of Scopulosus Bergenia, polished rice and pigeonpea, described Chinese medicine additive is made up of the raw medicinal material of following parts by weight: fourth grass in last of the ten Heavenly stems 20-35 weight portion, German tamarisk 17-31 weight portion, hooker winghead root 5-10 weight portion, bastard indigo 4-9 weight portion, arabian jasmine leaf 10-25 weight portion, Japanese Raspberry Root 10-15 weight portion, capsule of weeping forsythia 7-15 weight portion, radix paeoniae rubrathe 20-35 weight portion, almond 5-11 weight portion, Asian puccoon 10-20 weight portion, ilex pubescens 20-35 weight portion, waterlettuce herb 10-18 weight portion, arrowhead 15-25 weight portion, Radix Glycyrrhizae 20-30 weight portion, Scirpus tabernaemontani 15-28 weight portion, cassia twig 10-15 weight portion, forestry greenstar root 10-15 weight portion, rhizome of Scopulosus Bergenia 5-12 weight portion, polished rice 10-22 weight portion and pigeonpea 10-15 weight portion.
8. the bred pigs mixed feed according to any one of claim 1-7, it is characterized in that, described Chinese medicine additive is made up of the raw medicinal material of following parts by weight: fourth grass in the last of the ten Heavenly stems 27 weight portions, German tamarisk 23 weight portion, hooker winghead root 6 weight portion, bastard indigo 6 weight portion, arabian jasmine leaf 17 weight portion, Japanese Raspberry Root 12 weight portion, the capsule of weeping forsythia 10 weight portion, the radix paeoniae rubrathe 26 weight portion, almond 7 weight portion, Asian puccoon 15 weight portion, ilex pubescens 27 weight portion, waterlettuce herb 14 weight portion, arrowhead 20 weight portion, Radix Glycyrrhizae 24 weight portion Scirpus tabernaemontani 21 weight portion, cassia twig 12 weight portion, forestry greenstar root 13 weight portion, rhizome of Scopulosus Bergenia 7 weight portion, polished rice 16 weight portion and pigeonpea 12 weight portion.
9. the bred pigs mixed feed according to any one of claim 1-8, is characterized in that, the preparation method of described Chinese medicine additive is:
The first step, mixes in proportion by each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, adds hot reflux 1 ~ 3 hour, extracts, and filters acquisition first extract; Filter the dregs of a decoction obtained to add relative to the determining alcohol of described dregs of a decoction quality 1 ~ 2 times to be again the ethanol of 85 ~ 95%, to add hot reflux 1 ~ 3 hour that acquisition second extract is filtered in extraction; First extract and the second extract are merged, reduced pressure concentration removing alcohol solvent, dry, obtain and get dry extract;
Second step, is placed on the dry cream that the first step obtains in micronizer and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;
3rd step, adds the starch relative to its quality 2 ~ 4 times in the micropowders obtained by second step, mixing, obtains powder.
10. the preparation method of the bred pigs mixed feed according to any one of claim 1-9, is characterized in that, described preparation method is:
Pulverising step: take the millet, rapeseed dregs and the Brussels sprouts that boil by weight, drops into pulverizer and pulverizes;
Blend step: by weight by after cucumber dry powder, salt, Choline Chloride, corn oil, vitamin premix, microelement pre-mix material and Chinese medicine additive premixed, more fully mix with the comminuting matter obtained in pulverising step;
Granulation step: drop into granulator, granulates, makes its gelatinization degree reach 90% at 70-80 DEG C.
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