CN104844522A - 吗啉硝唑晶体及其制备方法和医药用途 - Google Patents
吗啉硝唑晶体及其制备方法和医药用途 Download PDFInfo
- Publication number
- CN104844522A CN104844522A CN201510224479.1A CN201510224479A CN104844522A CN 104844522 A CN104844522 A CN 104844522A CN 201510224479 A CN201510224479 A CN 201510224479A CN 104844522 A CN104844522 A CN 104844522A
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- CN
- China
- Prior art keywords
- nitre azoles
- preparation
- crystal
- morpholine nitre
- morpholine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/95—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by nitrogen atoms, attached to other ring members
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
2θ(°) | 10.179 | 16.302 | 17.273 | 19.724 | 21.675 | 22.567 | 24.342 | 26.202 | 27.185 | 29.480 | 33.188 |
D值 | 8.684 | 5.433 | 5.130 | 4.498 | 4.097 | 3.937 | 3.654 | 3.398 | 3.278 | 3.028 | 2.697 |
Claims (10)
Priority Applications (1)
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CN201510224479.1A CN104844522B (zh) | 2015-05-05 | 2015-05-05 | 吗啉硝唑晶体及其制备方法和医药用途 |
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CN201510224479.1A CN104844522B (zh) | 2015-05-05 | 2015-05-05 | 吗啉硝唑晶体及其制备方法和医药用途 |
Publications (2)
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CN104844522A true CN104844522A (zh) | 2015-08-19 |
CN104844522B CN104844522B (zh) | 2017-07-25 |
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CN (1) | CN104844522B (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106674124A (zh) * | 2015-11-09 | 2017-05-17 | 陕西合成药业股份有限公司 | 一种盐酸左旋吗啉硝唑晶型及其制备方法和用途 |
CN106699669A (zh) * | 2015-11-18 | 2017-05-24 | 陕西合成药业股份有限公司 | 一种左旋吗啉硝唑晶型及其制备方法和药用组合物的用途 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1605586A (zh) * | 2003-10-08 | 2005-04-13 | 连云港恒邦医药科技有限公司 | α-取代的2-甲基-5-硝基咪唑-1-乙醇衍生物 |
WO2006058457A1 (fr) * | 2004-11-30 | 2006-06-08 | Lianyungang Hengbang Pharmaceutical Co. Ltd. | DÉRIVÉS DE 2-MÉTHYL-5-NITROIMIDAZOL-1-ÉTHANOL α-SUBSTITUÉS |
CN1981764A (zh) * | 2005-12-13 | 2007-06-20 | 江苏豪森药业股份有限公司 | α-(吗啉-1-基)甲基-2-甲基-5-硝基咪唑-1-乙醇在制备抗滴虫、抗阿米巴原虫药物的用途 |
CN102199147A (zh) * | 2011-03-19 | 2011-09-28 | 陕西合成药业有限公司 | 用于治疗的硝基咪唑衍生物 |
-
2015
- 2015-05-05 CN CN201510224479.1A patent/CN104844522B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1605586A (zh) * | 2003-10-08 | 2005-04-13 | 连云港恒邦医药科技有限公司 | α-取代的2-甲基-5-硝基咪唑-1-乙醇衍生物 |
WO2006058457A1 (fr) * | 2004-11-30 | 2006-06-08 | Lianyungang Hengbang Pharmaceutical Co. Ltd. | DÉRIVÉS DE 2-MÉTHYL-5-NITROIMIDAZOL-1-ÉTHANOL α-SUBSTITUÉS |
CN1981764A (zh) * | 2005-12-13 | 2007-06-20 | 江苏豪森药业股份有限公司 | α-(吗啉-1-基)甲基-2-甲基-5-硝基咪唑-1-乙醇在制备抗滴虫、抗阿米巴原虫药物的用途 |
CN102199147A (zh) * | 2011-03-19 | 2011-09-28 | 陕西合成药业有限公司 | 用于治疗的硝基咪唑衍生物 |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106674124A (zh) * | 2015-11-09 | 2017-05-17 | 陕西合成药业股份有限公司 | 一种盐酸左旋吗啉硝唑晶型及其制备方法和用途 |
CN106699669A (zh) * | 2015-11-18 | 2017-05-24 | 陕西合成药业股份有限公司 | 一种左旋吗啉硝唑晶型及其制备方法和药用组合物的用途 |
Also Published As
Publication number | Publication date |
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CN104844522B (zh) | 2017-07-25 |
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Address after: Tenth Industrial Zone, Lianyungang, Jiangsu, China, 222047 Applicant after: JIANGSU HANSOH PHARMACEUTICAL GROUP Co.,Ltd. Address before: Tenth Industrial Zone, Lianyungang, Jiangsu, China, 222047 Applicant before: Jiangsu best Pharmaceutical Co.,Ltd. Address after: Tenth Industrial Zone, Lianyungang, Jiangsu, China, 222047 Applicant after: Jiangsu best Pharmaceutical Co.,Ltd. Address before: Tenth Industrial Zone, Lianyungang, Jiangsu, China, 222047 Applicant before: JIANGSU HANSOH PHARMACEUTICAL Co.,Ltd. |
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