CN104826032A - Pure traditional Chinese medicine preparation for treating emphysema and preparing method thereof - Google Patents

Abstract

The invention belongs to the technical field of traditional Chinese medicines and particularly relates to pure traditional Chinese medicine preparation for treating emphysema. The pure traditional Chinese medicine preparation comprises oroxylum indicum vent, periostracum cicadae, curcuma zedoary, fructus schizandrae, loguat leaf, perillaseed, angelica sinensis, wax gourd peel, bombyx batryticatus, paeonia suffruticosa, astragalus mongholicus, white peony root, asarum, rhizoma atractylodis, lucid ganoderma, snake gourd seed, radix ophiopogonis and the like. The traditional Chinese medicine preparation has the advantages that the traditional Chinese medicine preparation has functions of strengthening healthy energy and cultivating the foundation, prompting blood circulation and to remove blood stasis, reinforcing qi and nourishing blood, enhancing body immunity, and enhancing lung alveoli microcirculation; the pure traditional Chinese medicine preparation is appropriate in medicine matching, the medicines cooperate to tonify qi and constrain the lung, depress qi and reduce phlegm, free the lung and relieve asthma and nourish yin and the lung; the pure traditional Chinese medicine preparation is evident in curative effect, low in side effect and low in cost; the matched medicines conform to the traditional Chinese medicine and modern pharmacological research theories, and the pure traditional Chinese medicine preparation is safe, free of toxic and side effects and worthy of wide popularization and application.

Description

One treats emophysematous pure Chinese medicinal preparation and preparation method thereof

Technical field

The invention belongs to technical field of traditional Chinese pharmacology, be specifically related to one and treat emophysematous pure Chinese medicinal preparation and preparation method thereof.

Background technology

Emphysema refer to the air flue elasticity attenuation of terminal bronchiole far-end, and excessive expansion, inflation and Pulmonary volume increase or simultaneously with the pathological state that airway walls is destroyed.It is generally acknowledged that emophysematous morbidity is relevant with bronchial obstruction and protease-antiprotease imbalance.Smoking, infection and atmospheric pollution etc. cause bronchioles inflammation, luminal stenosis or obstruction.Bronchioles lumen distention during air-breathing, air enters alveolar; During expiration, tube chamber reduces, air trapping, and alveolar pressure constantly increases, and causes pulmonary alveolar overdistension even to break.The radial loss of traction of peribronchiolar, makes bronchioles shrink, and causes tube chamber stenosis.Pulmonary Vascular intimal thickening, alveolar wall blood is for reducing, and alveolar elasticity weakens, and encourages the rupture of alveoli expanded.In the situations such as infection, body endoprotease activity increases.The rejection ability of α1 antitrypsin deficiency person to protease weakens, therefore more easily emphysema occurs.The traditional Chinese medical science is thought, emphysema are many by YIN-deficiency of both the heart and lung, and yang hyperactivity is got angry, caused by lung-heat QI rising in reverse order.Therefore control suitable lung heat clearing heat extraction, spleen invigorating of nourishing heart is main.

According to theory of Chinese medical science, for emophysematous pathogeny, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.But at the emophysematous field of Chinese medicines for the treatment of, treatment by Chinese herbs effect is obvious not, moreover it is slower to take effect, so that large quantities of emphysema patient can not get the treatment of active drug for a long time, the state of an illness increases the weight of gradually.For problem set forth above, the invention provides one and treat emophysematous Chinese medicine, it is obvious not that it can solve effect in this type for the treatment of by Chinese herbs in the past, take effect slower problem, and effective, instant effect, has Be very effective, drug effect is definite, the advantage of quick result.

Summary of the invention

In order to overcome deficiency of the prior art, the invention provides stable curative effect, having no side effect, the emophysematous Chinese medicine for the treatment of with low cost.

In order to solve the problems of the technologies described above, the technical solution used in the present invention is as follows: one treats emophysematous pure Chinese medicinal preparation, is made up of each component of following parts by weight: Semen Oroxyli 2-10 part, Periostracum Cicadae 2-15 part, Rhizoma Curcumae 1-10 part, Fructus Schisandrae Chinensis 1-8 part, Folium Eriobotryae 2-18 part, Fructus Perillae 1-13 part, Radix Angelicae Sinensis 2-8 part, Exocarpium Benincasae 1-11 part, Bombyx Batryticatus 2-9 part, Cortex Moutan 1-9 part, Radix Astragali 2-19 part, Radix Paeoniae Alba 3-10 part, Herba Asari 1-6 part, Rhizoma Atractylodis 1-6 part, Radix Angelicae Dahuricae 1-8 part, Ganoderma 1-5 part, Semen Trichosanthis 1-14 part, Radix Ophiopogonis 2-15 part.

Further, the present invention also comprises following parts by weight: Bal(n)phyllia sp. 2-11 part, Cortex Mori 3-15 part, Poria 2-19 part, Semen Persicae 1-10 part, Flos Lonicerae 2-14 part, Herba Taraxaci 2-17 part, Radix Codonopsis 1-11 part, Galla Turcica (Galla Helepensis) 1-12 part.

Further, the present invention also comprises following parts by weight: Rhizoma Zingiberis 1-8 part, Fructus Aurantii 1-6 part, Cortex Lycii 1-8 part, Fructus Xanthii (parched) 2-10 part, Pericarpium Citri Reticulatae Viride 2-16 part, Rhizoma Arisaematis 1-5 part.

Further, the present invention includes following parts by weight: Semen Oroxyli 2-10 part, Periostracum Cicadae 2-15 part, Rhizoma Curcumae 1-10 part, Fructus Schisandrae Chinensis 1-8 part, Folium Eriobotryae 2-18 part, Fructus Perillae 1-13 part, Radix Angelicae Sinensis 2-8 part, Exocarpium Benincasae 1-11 part, Bombyx Batryticatus 2-9 part, Cortex Moutan 1-9 part, Radix Astragali 2-19 part, Radix Paeoniae Alba 3-10 part, Herba Asari 1-6 part, Rhizoma Atractylodis 1-6 part, Radix Angelicae Dahuricae 1-8 part, Ganoderma 1-5 part, Semen Trichosanthis 1-14 part, Radix Ophiopogonis 2-15 part, Bal(n)phyllia sp. 2-11 part, Cortex Mori 3-15 part, Poria 2-19 part, Semen Persicae 1-10 part, Flos Lonicerae 2-14 part, Herba Taraxaci 2-17 part, Radix Codonopsis 1-11 part, Galla Turcica (Galla Helepensis) 1-12 part, Rhizoma Zingiberis 1-8 part, Fructus Aurantii 1-6 part, Cortex Lycii 1-8 part, Fructus Xanthii (parched) 2-10 part, Pericarpium Citri Reticulatae Viride 2-16 part, Rhizoma Arisaematis 1-5 part.

Further, the present invention includes following parts by weight: Semen Oroxyli 2 parts, Periostracum Cicadae 2 parts, Rhizoma Curcumae 1 part, Fructus Schisandrae Chinensis 2 parts, Folium Eriobotryae 2 parts, Fructus Perillae 3 parts, Radix Angelicae Sinensis 2 parts, Exocarpium Benincasae 1 part, Bombyx Batryticatus 2 parts, Cortex Moutan 3 parts, the Radix Astragali 8 parts, the Radix Paeoniae Alba 3 parts, Herba Asari 1 part, Rhizoma Atractylodis 1 part, the Radix Angelicae Dahuricae 1 part, Ganoderma 1 part, Semen Trichosanthis 1 part, Radix Ophiopogonis 2 parts, Bal(n)phyllia sp. 2 parts, Cortex Mori 3 parts, 2 parts, Poria, 2 parts, Semen Persicae, Flos Lonicerae 4 parts, Herba Taraxaci 7 parts, Radix Codonopsis 1 part, Galla Turcica (Galla Helepensis) 2 parts, Rhizoma Zingiberis 2 parts, Fructus Aurantii 3 parts, Cortex Lycii 2 parts, Fructus Xanthii (parched) 2 parts, 2 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Arisaematis 1 part.

Further, the present invention is any one dosage form of pharmacy.

Further, the present invention treats emophysematous pure Chinese medicinal preparation, preparation process:

(1) above-mentioned Radix Notoginseng, Ganoderma are ground into fine powder respectively, cross 200 mesh standard sieves;

(2) by soak by water secondary medicinal in remainder, add water as the 2-15 times amount of medical material weight at every turn, decoct secondary, each 2-5 hour, filter, filtrate is condensed into the clear paste that relative density is 1.10-1.25, and adding ethanol to making containing amount of alcohol is 60%, stirs, leave standstill 10 hours, filter, collect filtrate and reclaim ethanol, being condensed into the extractum containing solid weight 65-67%;

(3) prepare dosage form technique according to pharmacy, by step (1) fine powder and step (2) extractum, add dosage form adjuvant, prepare corresponding dosage form.

Further, present invention also offers the application of pure Chinese medicinal preparation in treatment emphysema.

Chinese medicine selected by the present invention has following pharmacological action:

Semen Oroxyli: nature and flavor: bitter, cold.1. " south of the Five Ridges gather medicinal herbs record ": " sour in the mouth is bitter." 2. " medical material compilation of data ": " bitter in the mouth, cold." 3. " Guangxi Chinese medicinal herbal ": " slightly sweet flavor, cool in nature, nontoxic." return through: enter lung, Liver Channel.1. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " enter lung, spleen, stomach warp." 2. " south of the Five Ridges gather medicinal herbs record ": " enters Liver Channel." function cures mainly: lung moistening, soothing liver-QI, stomach function regulating, granulation promoting.Control cough, sore throat, hoarseness, stomachache due to hyperactive liver-QI attacking the stomach, the open sore part is not held back.Control dry cough and incessantly often join Spica Prunellae.1. " Yunnan leads to will ": " burn for ash, can heart pain be controlled." 2. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " Dingchuan, expectorant, broken legendary venomous insect amasss, except the poison of tympanitis due to blood stasis, gas legendary venomous insect.Again can tonify deficiency, alleviating distention in middle-JIAO, feed." 3. " detailed outline is picked up any lost article from the road ": " controls heart pain, and irritability pain, bottom is damp and hot.Xiang Qiuzi cloud again, all carbuncle poison do not close up, and paste it with this." 4. " south of the Five Ridges gather medicinal herbs record ": " expectorant fire, except eying covetously." 5. " modern Practical Chinese medicinal ": " antitussive, controls pertussis and dryness tracheitis." 6. " medical material compilation of data ": " controls throat aphonia." 7. Guangzhou army " conventional Chinese herbal medicine handbook ": " clearing away lung-heat, throat.Treating acute and chronic bronchitis, pulmonary tuberculosis is coughed, laryngopharynx swelling and pain, tonsillitis."

Periostracum Cicadae: nature and flavor: Gan Xian is cool.1. " detailed outline ": " salty sweet, cold, nontoxic." 2. " book on Chinese herbal medicine just ": " taste is micro-sweet micro-salty, slightly cool in nature." 3. " king Chinese catalpa medicine solution ": " acrid in the mouth, gas is put down." return through: enter lung, Liver Channel.1. " Bencao Jingshu ": " enter liver." 2. " book on Chinese herbal medicine is new again ": " enters liver, spleen, lung three warp." function cures mainly: loose wind heat, lung qi dispersing, determines convulsion.Control affection due to external wind and heat, cough hoarseness, measles is sent out not smooth thoroughly, rubella pruritus, pediatric epilepsy scared, conjunctival congestion, cataracta, furuncle swelling toxin, tetanus.

Rhizoma Curcumae: nature and flavor: toil, temperature.Enter liver, spleen channel.Function cures mainly: removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.For abdominal pain due to blood stasis, hepatosplenomegaly, trusted subordinate's distending pain, gather, women's blood stasis amenorrhea, traumatic injury is had a pain eating accumulation.(1) promoting the circulation of QI to relieve pain, removing blood stasis removing food stagnancy: for the amenorrhea of qi depression to blood stasis, chest and hypochondrium, stomachache and lump in the abdomen lump etc.Often join Rhizoma Sparganii.(2) promoting digestion and removing stagnation: for the stomach abdominal distention and pain of eating accumulation, often join Fructus Hordei Germinatus (parched to brown), Semen Arecae Prepareta.

Fructus Schisandrae Chinensis: nature and flavor: sour in the mouth; Warm in nature; Gui Jing: lung; The heart; Kidney channel; Function cures mainly: restrain astringent or styptic treatment for spontaneous sweating; Supplementing QI for promoting the production of body fluid; Mind tranquilizing and the heart calming.Main cough dyspnea due to deficiency; Emission; Urinate the quite enuresis; Incessant chronic diarrhea; Spontaneous sweating; Tianjin wound is thirsty; Palpitation and insomnia.

Folium Eriobotryae: nature and flavor: bitter, pungent; Cold; Nontoxic.Gui Jing: lung; The heart; Stomach warp.Function cures mainly: clearing away lung-heat to relieve cough, and regulating the stomach and sending down the abnormal ascending QI is quenched the thirst.Main lung-heat phlegmatic cough; Deficiency of YIN chronic cough; Hemoptysis; Epistaxis; Gastric heat is vomitted the sound of vomiting.

Fructus Perillae: nature and flavor: pungent; Temperature; Nontoxic.Gui Jing: lung; Spleen; Large intestine channel.Function cures mainly: the therapeutic method to keep the adverse QI flowing downwards; Expectorant; Lung moistening; Wide intestinal.Main cough with dyspnea; Phlegm dyspnea; Stagnation of QI constipation.

Radix Angelicae Sinensis: nature and flavor: sweet, acrid, warm.Gui Jing: return liver, the heart, spleen channel.Function cures mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.

Exocarpium Benincasae: nature and flavor: sweet is cool.Gui Jing: return spleen, small intestine meridian.Function cures mainly; Inducing diuresis to remove edema.For edema distension, dysuria, summer-heat is thirsty, oliguria with reddish urine

Bombyx Batryticatus: nature and flavor: salty, pungent is flat.Gui Jing: return liver, lung, stomach warp.Function cures mainly: expelling wind for relieving convulsion, dissipating phlegm and resolving masses.For convulsion with spasms, laryngopharynx swelling and pain, skin pruritus, submandibular lymph nodes is scorching, facial paralysis.

Cortex Moutan: nature and flavor: arduous; Cool; Be slightly cold; Gui Jing: the heart; Liver; Kidney; Lung meridian.Function cures mainly: heat clearing away; Promoting blood circulation to remove blood stasis.The main epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The pathogenic bacteria later stage brimful of tears, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and flutter the pain of injury; Beriberoid pyretic arthralgia.

The Radix Astragali: nature and flavor: sweet, temperature.Gui Jing: return lung, spleen channel.Function cures mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.

The Radix Paeoniae Alba: nature and flavor: bitter, sour, is slightly cold.Gui Jing: return liver, spleen channel.Function cures mainly: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.

Herba Asari: nature and flavor: pungent; Temperature; Mild toxicity.Gui Jing: lung; Kidney; The heart; Liver; Gallbladder; Spleen channel.Function cures mainly: cold expelling dispels the wind; Pain relieving; Warming the lung to resolve fluid-retention; Sensible.Main exterior syndrome due to wind-cold; Headache, toothache; Rheumatic arthralgia; Phlegm retention cough with asthma; Nasal obstruction; Nasal sinusitis; Aphtha.

Rhizoma Atractylodis: nature and flavor: arduous, temperature.1. amplification on Canon of Materia Medica: " abnormal smells from the patient is pungent strong." 2. " pearl sac ": " Gan Xin." 3. " brilliant essence of converging is wanted ": " bitter but sweet flavor, warm in nature, nontoxic." return through: enter spleen, stomach warp.1. " pearl sac ": " foot sun is bright, lunar." 2. " detailed outline ": " enter foot too yin, yang is bright, hands is lunar, the warp of the sun." 3. " book on Chinese herbal medicine is newly organized ": " enters bright, the Taiyang channel of foot sun." 4. " book on Chinese herbal medicine is new again ": " enters spleen, liver two warp." function cures mainly: spleen invigorating, dampness, resolving depression, wards off dirty.Control wet Sheng and be stranded spleen, asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting, has loose bowels, dysentery, malaria, phlegm retention, edema, and seasonal epidemic pathogens is caught a cold, anemofrigid-damp arthralgia, flaccidity of the lower limbs, nyctalopia.

The Radix Angelicae Dahuricae: nature and flavor: pungent, temperature.Gui Jing: return stomach, large intestine, lung meridian.Function cures mainly: loose wind dehumidifying, understand things pain-stopping, detumescence and apocenosis.For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.

Ganoderma: nature and flavor: sweet; Flat; Nontoxic.Gui Jing: lung; The heart; Spleen; Kidney channel.Function cures mainly: replenishing QI and blood; Tranquilizing mind; Strengthening the spleen and stomach.Main asthenia; Cardiopalmus; Insomnia; Dizzy; Spiritlessness and weakness; Chronic cough is panted; Coronary heart disease; Silicosis; Tumor.

Semen Trichosanthis: nature and flavor: sweet, cold.Gui Jing: return lung, stomach, large intestine channel.Function cures mainly: moistening the lung and resolving phlegm, laxation relieving constipation.Stick for cough caused by dryness expectorant, dryness of the intestine constipation.

Radix Ophiopogonis: nature and flavor: sweet, micro-hardship, is slightly cold.Gui Jing: GUIXIN, lung, stomach warp.Function cures mainly: YIN nourishing and the production of body fluid promoting, and lung moistening clears away heart-fire.For dryness of the lung dry cough.Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.

Bal(n)phyllia sp.: nature and flavor: sweet; Salty; Temperature; Nontoxic.Gui Jing: lung; Kidney; Stomach warp.Function cures mainly: warming the lung; Tonifying YANG; Lactogenesis.Main lung cold chronic cough; Asthenia cough with asthma; Impotence and premature ejaculation; Emission; Cold arthralgia of loins and legs; Galactostasis.

Cortex Mori: nature and flavor: sweet, cold.Gui Jing: return lung meridian.Function cures mainly: eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema.For dyspnea and cough due to lung-heat, edema distension oliguria, appearance skin edema.

Poria: nature and flavor: sweet, light is flat.Gui Jing: GUIXIN, lung, spleen, kidney channel.Function cures mainly: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.

Semen Persicae: nature and flavor: bitter sweet; Flat; Nontoxic.Gui Jing: the heart; Liver; Large intestine; Lung; Spleen channel.Function cures mainly: blood stasis removing and clots absorbing; Moisturize laxation.Main warp closes; Lump in the abdomen; Calentura blood-retention; Migratory arthralgia; Malaria; Traumatic injury; Swelling and pain due to blood stasis; The dry constipation of blood.

Flos Lonicerae: nature and flavor: sweet, cold.Gui Jing: return lung, the heart, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat.

Herba Taraxaci: nature and flavor: bitter, sweet, cold.Gui Jing: return liver, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.

Radix Codonopsis: nature and flavor: sweet is flat.Gui Jing: return spleen, lung meridian.Function cures mainly: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.

Galla Turcica (Galla Helepensis): nature and flavor: bitter, temperature.1. Tang materia medica ": " bitter in the mouth, temperature, nontoxic." 2. " Haiyao Bencao, Oversea Materia Medica ": " Wen Ping is nontoxic." return through: enter lung, spleen, kidney channel.1. " beautiful Chinese catalpa medicine solution ": " enter kidney meridian, liver channel of foot-Jueyin." 2. " book on Chinese herbal medicine is looked for the truth ": " enters kidney, double enter spleen, stomach." 3. " about can cure mirror ": " enters lung, kidney two warp." function cures mainly: solid and gas, and arresting seminal emission is astringed the lung, hemostasis.Control asthenia of the large intestine sliding, dysentery is more than, has blood in stool, seminal emission, polyhidrosis around the external genitals, cough, and spitting of blood, toothache, wound hemorrhage, skin infection does not close up for a long time.

Rhizoma Zingiberis: nature and flavor: pungent, hot.Gui Jing: return spleen, stomach, kidney, the heart, lung meridian.Function cures mainly: Rhizoma Zingiberis warming spleen and stomach for dispelling cold, and recuperating depleted YANG is promoted blood circulation, dampness expectorant.For coldness and pain in the epigastrium, vomiting is had loose bowels, and cold extremities faint pulse, phlegm retention is breathed with cough.

Fructus Aurantii: nature and flavor: bitter, pungent, sour, temperature.Gui Jing: return spleen, stomach warp.Function cures mainly: regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, sub-official's prolapsus.

Cortex Lycii: nature and flavor: sweet, cold.Gui Jing: return lung, liver, kidney channel.Function cures mainly: removing heat from blood removes and steams, lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis, interior-heat is quenched one's thirst.

Fructus Xanthii (parched): nature and flavor: pungent, bitter, temperature; Poisonous.Gui Jing: return lung meridian.Function cures mainly: loose wind dehumidifying, clearing the nasal passage.For headche due to wind-cold, nasal sinusitis watery nasal discharge, rubella pruritus, arthralgia chiefly caused by damp pathogen contracture.

Pericarpium Citri Reticulatae Viride: nature and flavor: bitter, pungent, temperature.Gui Jing: return liver, gallbladder, stomach warp.Function cures mainly: soothing the liver dispelling the stagnated QI, removing food stagnancyization is stagnant.For distending pain in the chest and hypochondrium, hernia, nodule in the breast, acute mastitis, abdominal pain due to retention of food.

Rhizoma Arisaematis: nature and flavor: bitter, pungent, temperature; Poisonous.Gui Jing: return lung, liver, spleen channel.Function cures mainly: drying dampness to eliminate phlegm, expellings wind and relieving convulsion, mass dissipating and swelling eliminating.For pertinacious phlegm cough, dizziness due to wind-phlegm, middle wind-phlegm is stopped up, facial hemiparalysis, hemiplegia, epilepsy, infantile convulsion, tetanus.Life uses external treatment carbuncle, snake bite and insect sting.

The body resistance strengthening and constitution consolidating of the present invention, blood circulation promoting and blood stasis dispelling, benefiting QI and nourishing blood, enhancing human body immunity power, strengthens alveolar microcirculation.The all medicine compatibilities of the present invention, bring out the best in each other, play the body resistance strengthening and constitution consolidating altogether, benefiting QI and nourishing blood, blood circulation promoting and blood stasis dispelling, QI invigorating are astringed the lung, lowering the adverse-rising QI to resolve phlegm, depressed lung-energy dispersing, and YIN nourishing supports lung.The present invention is evident in efficacy, side effect is little, with low cost.Selected by the present invention, medical material compatibility is suitable, and meet the traditional Chinese medical science and modern pharmacological research theory, with low cost, safe without toxic side effect, should be widely promoted application.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

Clinical efficacy is summed up:

One, general data: this Chinese medicine preparation is applied to clinical observation case 137 example, 30 ~ 75 years old age.

Two, usage and dosage: during clinical practice, the amounts of components of this Chinese medicine preparation takes the circumstances into consideration increase and decrease according to the body weight of patient and age.

Therapeutic process: take following prescription drug, one day three times 7 days is a course for the treatment of.

Semen Oroxyli 2 parts, Periostracum Cicadae 2 parts, Rhizoma Curcumae 1 part, Fructus Schisandrae Chinensis 2 parts, Folium Eriobotryae 2 parts, Fructus Perillae 3 parts, Radix Angelicae Sinensis 2 parts, Exocarpium Benincasae 1 part, Bombyx Batryticatus 2 parts, Cortex Moutan 3 parts, the Radix Astragali 8 parts, the Radix Paeoniae Alba 3 parts, Herba Asari 1 part, Rhizoma Atractylodis 1 part, the Radix Angelicae Dahuricae 1 part, Ganoderma 1 part, Semen Trichosanthis 1 part, Radix Ophiopogonis 2 parts, Bal(n)phyllia sp. 2 parts, Cortex Mori 3 parts, 2 parts, Poria, 2 parts, Semen Persicae, Flos Lonicerae 4 parts, Herba Taraxaci 7 parts, Radix Codonopsis 1 part, Galla Turcica (Galla Helepensis) 2 parts, Rhizoma Zingiberis 2 parts, Fructus Aurantii 3 parts, Cortex Lycii 2 parts, Fructus Xanthii (parched) 2 parts, 2 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Arisaematis 1 part.

Three, criterion of therapeutical effect:

(1) fully recover: cough, uncomfortable in chest, breathe hard, the sings and symptoms such as dyspnea disappears;

(2) effective: cough, uncomfortable in chest, breathe hard, the sings and symptoms such as dyspnea alleviates or obviously alleviates;

(3) invalid: symptom and sign are not improved.

Four, therapeutic effect: in this clinical observation case, takes medicine 2-5 the course for the treatment of, and recovery from illness 101 example, follows up a case by regular visits to and have no recurrence; Effective 18 examples, no effect 9.There is not toxic and side effects in treatments period.

Model case:

Xu so-and-so, female, 50 years old, instrument detected X-ray conclusion emphysema, the few expectorant of auscultation, breathed heavily, rang, the not blue or green and edema due to deficiency of face, both legs edema due to deficiency.Take medicine after 2 courses for the treatment of, disease amelioration, fully recovers after continuing to take a course for the treatment of.

Grandson so-and-so, man, 56 years old.Diagnosis transfers emphysema to by chronic bronchitis, dyspnea, uncomfortable in chest, cough, expectoration, asthma, with the dry moist rales etc. generated heat, pulmonary's audible is intensive.Take medicine after 2 courses for the treatment of, the symptom such as dyspnea, uncomfortable in chest, cough, expectoration alleviates, and fully recovers after continuing to take 2 courses for the treatment of.

Wu, man, 61 years old, diagnosis had chronic bronchitis to merge slight emphysema, normal recurrent cough, and expectoration is easily tired.Take medicine after 3 courses for the treatment of of the present invention, every ill symptoms all disappears, and body weight also increases to some extent, recovers.

Beam, female, 54 years old, is diagnosed as lung qi bubble, coughs, lacks expectorant, slight asthma.Fully recover after taking 2 courses for the treatment of of medicine of the present invention.

Song, female, 48 years old, Diagnosis of pulmonary bubble, constantly, breathe rapid, uncomfortable in chest, abundant expectoration color was white, thready and moderate pulse in cough.Take a turn for the better after taking 3 courses for the treatment of of the present invention, cure after continuing to take 1 course for the treatment of of the present invention.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is further elaborated.

Embodiment 1

Semen Oroxyli 2 parts, Periostracum Cicadae 2 parts, Rhizoma Curcumae 1 part, Fructus Schisandrae Chinensis 2 parts, Folium Eriobotryae 2 parts, Fructus Perillae 3 parts, Radix Angelicae Sinensis 2 parts, Exocarpium Benincasae 1 part, Bombyx Batryticatus 2 parts, Cortex Moutan 3 parts, the Radix Astragali 8 parts, the Radix Paeoniae Alba 3 parts, Herba Asari 1 part, Rhizoma Atractylodis 1 part, the Radix Angelicae Dahuricae 1 part, Ganoderma 1 part, Semen Trichosanthis 1 part, Radix Ophiopogonis 2 parts, Bal(n)phyllia sp. 2 parts, Cortex Mori 3 parts, 2 parts, Poria, 2 parts, Semen Persicae, Flos Lonicerae 4 parts, Herba Taraxaci 7 parts, Radix Codonopsis 1 part, Galla Turcica (Galla Helepensis) 2 parts, Rhizoma Zingiberis 2 parts, Fructus Aurantii 3 parts, Cortex Lycii 2 parts, Fructus Xanthii (parched) 2 parts, 2 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Arisaematis 1 part.

Preparation process:

(1) above-mentioned Radix Notoginseng, Ganoderma are ground into fine powder respectively, cross 200 mesh standard sieves;

(2) by soak by water secondary medicinal in remainder, add water as 5 times amount of medical material weight at every turn, decoct secondary, each 2 hours, filter, filtrate is condensed into the clear paste that relative density is 1.10-1.25, and adding ethanol to making containing amount of alcohol is 60%, stirs, leave standstill 10 hours, filter, collect filtrate and reclaim ethanol, being condensed into the extractum containing solid weight 65-67%;

(3) prepare dosage form technique according to pharmacy, by step (1) fine powder and step (2) extractum, add capsule formulation adjuvant, after mix homogeneously, upper capsule machine, is prepared into capsule formulation.

Embodiment 2

Butterfly 2 parts, Periostracum Cicadae 2 parts, Rhizoma Curcumae 1 part, Fructus Schisandrae Chinensis 2 parts, Folium Eriobotryae 2 parts, Fructus Perillae 3 parts, Radix Angelicae Sinensis 2 parts, Exocarpium Benincasae 1 part, Bombyx Batryticatus 2 parts, Cortex Moutan 3 parts, the Radix Astragali 8 parts, the Radix Paeoniae Alba 3 parts, Herba Asari 1 part, Rhizoma Atractylodis 1 part, the Radix Angelicae Dahuricae 1 part, Ganoderma 1 part, Semen Trichosanthis 1 part, Radix Ophiopogonis 2 parts.

Preparation process:

(1) above-mentioned Radix Notoginseng, Ganoderma are ground into fine powder respectively, cross 200 mesh standard sieves;

(2) by soak by water secondary medicinal in remainder, add water as 5 times amount of medical material weight at every turn, decoct secondary, each 2 hours, filter, filtrate is condensed into the clear paste that relative density is 1.10-1.25, and adding ethanol to making containing amount of alcohol is 60%, stirs, leave standstill 10 hours, filter, collect filtrate and reclaim ethanol, being condensed into the extractum containing solid weight 65-67%;

(3) prepare dosage form technique according to pharmacy, by step (1) fine powder and step (2) extractum, add pill adjuvant, be prepared into pill.

Embodiment 3

Butterfly 2 parts, Periostracum Cicadae 2 parts, Rhizoma Curcumae 1 part, Fructus Schisandrae Chinensis 2 parts, Folium Eriobotryae 2 parts, Fructus Perillae 3 parts, Radix Angelicae Sinensis 2 parts, Exocarpium Benincasae 1 part, Bombyx Batryticatus 2 parts, Cortex Moutan 3 parts, the Radix Astragali 8 parts, the Radix Paeoniae Alba 3 parts, Herba Asari 1 part, Rhizoma Atractylodis 1 part, the Radix Angelicae Dahuricae 1 part, Ganoderma 1 part, Semen Trichosanthis 1 part, Radix Ophiopogonis 2 parts, Bal(n)phyllia sp. 5 parts, Cortex Mori 5 parts, 8 parts, Poria, 7 parts, Semen Persicae, Flos Lonicerae 11 parts, Herba Taraxaci 12 parts, Radix Codonopsis 1 part, Galla Turcica (Galla Helepensis) 2 parts.

Preparation process:

(1) above-mentioned Radix Notoginseng, Ganoderma are ground into fine powder respectively, cross 200 mesh standard sieves;

(2) by soak by water secondary medicinal in remainder, add water as 3 times amount of medical material weight at every turn, decoct secondary, each 2 hours, filter, filtrate is condensed into the clear paste that relative density is 1.10-1.25, and adding ethanol to making containing amount of alcohol is 60%, stirs, leave standstill 10 hours, filter, collect filtrate and reclaim ethanol, being condensed into the extractum containing solid weight 65-67%;

(3) prepare dosage form technique according to pharmacy, by step (1) fine powder and step (2) extractum, add oral liquid formulations adjuvant, be prepared into oral liquid.

Embodiment 4

Butterfly 2 parts, Periostracum Cicadae 2 parts, Rhizoma Curcumae 1 part, Fructus Schisandrae Chinensis 2 parts, Folium Eriobotryae 2 parts, Fructus Perillae 3 parts, Radix Angelicae Sinensis 2 parts, Exocarpium Benincasae 1 part, Bombyx Batryticatus 2 parts, Cortex Moutan 3 parts, the Radix Astragali 8 parts, the Radix Paeoniae Alba 3 parts, Herba Asari 1 part, Rhizoma Atractylodis 1 part, the Radix Angelicae Dahuricae 1 part, Ganoderma 1 part, Semen Trichosanthis 1 part, Radix Ophiopogonis 2 parts, Rhizoma Zingiberis 8 parts, Fructus Aurantii 5 parts, Cortex Lycii 7 parts, Fructus Xanthii (parched) 2 parts, 2 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Arisaematis 1 part.

Preparation process:

(1) above-mentioned Radix Notoginseng, Ganoderma are ground into fine powder respectively, cross 200 mesh standard sieves;

(2) by soak by water secondary medicinal in remainder, add water as 4 times amount of medical material weight at every turn, decoct secondary, each 2 hours, filter, filtrate is condensed into the clear paste that relative density is 1.10-1.25, and adding ethanol to making containing amount of alcohol is 60%, stirs, leave standstill 10 hours, filter, collect filtrate and reclaim ethanol, being condensed into the extractum containing solid weight 65-67%;

(3) prepare dosage form technique according to pharmacy, by step (1) fine powder and step (2) extractum, add granular preparation adjuvant, prepare granule or powder.

Embodiment 5

Semen Oroxyli 8 parts, Periostracum Cicadae 4 parts, Rhizoma Curcumae 2 parts, Fructus Schisandrae Chinensis 3 parts, Folium Eriobotryae 8 parts, Fructus Perillae 6 parts, Radix Angelicae Sinensis 2 parts, Exocarpium Benincasae 1 part, Bombyx Batryticatus 2 parts, Cortex Moutan 3 parts, the Radix Astragali 8 parts, the Radix Paeoniae Alba 3 parts, Herba Asari 1 part, Rhizoma Atractylodis 1 part, the Radix Angelicae Dahuricae 1 part, Ganoderma 1 part, Semen Trichosanthis 1 part, Radix Ophiopogonis 2 parts, Bal(n)phyllia sp. 2 parts, Cortex Mori 3 parts, 2 parts, Poria, 2 parts, Semen Persicae, Flos Lonicerae 4 parts, Herba Taraxaci 7 parts, Radix Codonopsis 1 part, Galla Turcica (Galla Helepensis) 2 parts, Rhizoma Zingiberis 8 parts, Fructus Aurantii 5 parts, Cortex Lycii 7 parts, Fructus Xanthii (parched) 2 parts, 2 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Arisaematis 1 part.

Preparation process:

(1) above-mentioned Radix Notoginseng, Ganoderma are ground into fine powder respectively, cross 200 mesh standard sieves;

(2) by soak by water secondary medicinal in remainder, add water as 6 times amount of medical material weight at every turn, decoct secondary, each 2 hours, filter, filtrate is condensed into the clear paste that relative density is 1.10-1.25, and adding ethanol to making containing amount of alcohol is 60%, stirs, leave standstill 10 hours, filter, collect filtrate and reclaim ethanol, being condensed into the extractum containing solid weight 65-67%;

(3) prepare dosage form technique according to pharmacy, by step (1) fine powder and step (2) extractum, add tablet dose adjuvant, soft material processed, oven dry, tabletting are prepared into tablet.

The above, it is only preferred embodiment of the present invention, not any pro forma restriction is done to the present invention, therefore everyly do not depart from technical solution of the present invention content, the any simple modification done above embodiment according to technical spirit of the present invention, equivalent variations and modification, all still belong in the scope of technical solution of the present invention.

Claims (8)

1. treat an emophysematous pure Chinese medicinal preparation, it is characterized in that: be made up of each component of following parts by weight: Semen Oroxyli 2-10 part, Periostracum Cicadae 2-15 part, Rhizoma Curcumae 1-10 part, Fructus Schisandrae Chinensis 1-8 part, Folium Eriobotryae 2-18 part, Fructus Perillae 1-13 part, Radix Angelicae Sinensis 2-8 part, Exocarpium Benincasae 1-11 part, Bombyx Batryticatus 2-9 part, Cortex Moutan 1-9 part, Radix Astragali 2-19 part, Radix Paeoniae Alba 3-10 part, Herba Asari 1-6 part, Rhizoma Atractylodis 1-6 part, Radix Angelicae Dahuricae 1-8 part, Ganoderma 1-5 part, Semen Trichosanthis 1-14 part, Radix Ophiopogonis 2-15 part.

2. one according to claim 1 treats emophysematous pure Chinese medicinal preparation, it is characterized in that: also comprise following parts by weight: Bal(n)phyllia sp. 2-11 part, Cortex Mori 3-15 part, Poria 2-19 part, Semen Persicae 1-10 part, Flos Lonicerae 2-14 part, Herba Taraxaci 2-17 part, Radix Codonopsis 1-11 part, Galla Turcica (Galla Helepensis) 1-12 part.

3. one according to claim 1 treats emophysematous pure Chinese medicinal preparation, it is characterized in that: also comprise following parts by weight: Rhizoma Zingiberis 1-8 part, Fructus Aurantii 1-6 part, Cortex Lycii 1-8 part, Fructus Xanthii (parched) 2-10 part, Pericarpium Citri Reticulatae Viride 2-16 part, Rhizoma Arisaematis 1-5 part.

4. one according to claim 1 treats emophysematous pure Chinese medicinal preparation, it is characterized in that: comprise following parts by weight:

Semen Oroxyli 2-10 part, Periostracum Cicadae 2-15 part, Rhizoma Curcumae 1-10 part, Fructus Schisandrae Chinensis 1-8 part, Folium Eriobotryae 2-18 part, Fructus Perillae 1-13 part, Radix Angelicae Sinensis 2-8 part, Exocarpium Benincasae 1-11 part, Bombyx Batryticatus 2-9 part, Cortex Moutan 1-9 part, Radix Astragali 2-19 part, Radix Paeoniae Alba 3-10 part, Herba Asari 1-6 part, Rhizoma Atractylodis 1-6 part, Radix Angelicae Dahuricae 1-8 part, Ganoderma 1-5 part, Semen Trichosanthis 1-14 part, Radix Ophiopogonis 2-15 part, Bal(n)phyllia sp. 2-11 part, Cortex Mori 3-15 part, Poria 2-19 part, Semen Persicae 1-10 part, Flos Lonicerae 2-14 part, Herba Taraxaci 2-17 part, Radix Codonopsis 1-11 part, Galla Turcica (Galla Helepensis) 1-12 part, Rhizoma Zingiberis 1-8 part, Fructus Aurantii 1-6 part, Cortex Lycii 1-8 part, Fructus Xanthii (parched) 2-10 part, Pericarpium Citri Reticulatae Viride 2-16 part, Rhizoma Arisaematis 1-5 part.

5. one according to claim 4 treats emophysematous pure Chinese medicinal preparation, it is characterized in that: Semen Oroxyli 2 parts, Periostracum Cicadae 2 parts, Rhizoma Curcumae 1 part, Fructus Schisandrae Chinensis 2 parts, Folium Eriobotryae 2 parts, Fructus Perillae 3 parts, Radix Angelicae Sinensis 2 parts, Exocarpium Benincasae 1 part, Bombyx Batryticatus 2 parts, Cortex Moutan 3 parts, the Radix Astragali 8 parts, the Radix Paeoniae Alba 3 parts, Herba Asari 1 part, Rhizoma Atractylodis 1 part, the Radix Angelicae Dahuricae 1 part, Ganoderma 1 part, Semen Trichosanthis 1 part, Radix Ophiopogonis 2 parts, Bal(n)phyllia sp. 2 parts, Cortex Mori 3 parts, 2 parts, Poria, 2 parts, Semen Persicae, Flos Lonicerae 4 parts, Herba Taraxaci 7 parts, Radix Codonopsis 1 part, Galla Turcica (Galla Helepensis) 2 parts, Rhizoma Zingiberis 2 parts, Fructus Aurantii 3 parts, Cortex Lycii 2 parts, Fructus Xanthii (parched) 2 parts, 2 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Arisaematis 1 part.

6. treat emophysematous pure Chinese medicinal preparation according to the one described in claim 1 to 5, it is characterized in that: be any one dosage form of pharmacy.

7. one according to claim 6 treats emophysematous pure Chinese medicinal preparation, it is characterized in that: preparation process:

(1) above-mentioned Radix Notoginseng, Ganoderma are ground into fine powder respectively, cross 200 mesh standard sieves;

(2) by soak by water secondary medicinal in remainder, add water as the 2-15 times amount of medical material weight at every turn, decoct secondary, each 2-5 hour, filter, filtrate is condensed into the clear paste that relative density is 1.10-1.25, and adding ethanol to making containing amount of alcohol is 60%, stirs, leave standstill 10 hours, filter, collect filtrate and reclaim ethanol, being condensed into the extractum containing solid weight 65-67%;

(3) prepare dosage form technique according to pharmacy, by step (1) fine powder and step (2) extractum, add dosage form adjuvant, prepare corresponding dosage form.

8. the application of pure Chinese medicinal preparation according to claim 1 in treatment emphysema.