CN104825596A - Traditional Chinese medicine for treating angioneurotic edema - Google Patents

Abstract

The invention relates to a traditional Chinese medicine for treating angioneurotic edema. The traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 15 parts of alkanet, 9 parts of tribulusterrestris, 9 parts of schizonepeta, 15 parts of poria cocos, 15 parts of honeysuckle, 9 parts of periostracum cicada, 9 parts of cortex dictamni and 12 parts of plantain herb. Clinical experiments prove that the traditional Chinese medicine disclosed by the invention can be safely and effectively applied to treating angioneurotic edema.

Description

A kind of Chinese medicine being used for the treatment of vasodilation

Technical field

The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of vasodilation.

Background technology

Vasodilation is a kind of mucosa hydroderma of acute local response type, is department of stomatology commonly encountered diseases.Its pathological changes is apt to occur in Head And Face loose connective tissue place, as lip, tongue, cheek, palatine etc., can recurrent exerbation, and severe one causes laryngeal edema, even death by suffocation.Primary disease is relevant with factors such as some food, medicine, cosmetics, pollen, infection, sting.Vasodilation, also known as huge urticaria, belongs to Chinese medicine " urticaria ", " rubella wheal " category, is pented up, blood deficiency or heat in blood by skin noxious dampness, feels wind heat again and forms; Or the pungent savoury of surfeit, accumulated heat in gastrointestinal tract, feels ailment said due to cold or exposure again, makes disharmony of nutrient QI with defensive QI, damp and hot interior knot and falling ill.Sick recurrent exerbation is due to after various paathogenic factor causes the generation of this disease, cause local blood capillary sensitivity to increase, tube wall permeability increases, corium and a large amount of serum of subcutaneous tissue penetrate in loose connective tissue, western medicine can make capillary permeability recover normal, reduce oozing out and helping tissue resorption transudate of tissue fluid, but the state that site of pathological change capillary wall sensitivity excessively increases is not improved, still be in responsive excited state, various stimulation is (normal, improper) all may cause the increase of its Vascular Permeability, symptom forms repeated relapsing again.By the adjustment of effect such as expelling wind and clearing away heat, removing pathogenic heat from blood and toxic substance from the body, benefiting QI for strengthening the superficies of Chinese medicine, improve the physiological status of local blood capillary, thus reduce its sensitivity.

Medical material present Research involved in the present invention is as follows:

Radix Arnebiae (Radix Lithospermi) [another name] gromwell root, Radix Arnebiae.[source] this product is the dry root of comfrey lithospermum euchromum Royle, Radix Arnebiae (Radix Lithospermi) or arnebia guttata Bunge.Spring, Qiu Erji excavate, removing silt, dry.[nature and flavor] are sweet, salty, cold.[return through] GUIXIN, Liver Channel.[function cures mainly] removing heat from blood, invigorates blood circulation, removing toxic substances rash.Contain for heat in blood poison, macule purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire.[usage and dosage] takes orally: decoct soup, 5-9g.[attention] gastrointestinal is weak, the careful clothes of stool lingering diarrhea person.[extracts] " China's book on Chinese herbal medicine ".

Fructus Atriplicis Sibiricae [another name] Fructus Tribuli, Fructus Atriplicis Sibiricae, hard Fructus Tribuli.[source] this product is the dry mature fruit of zygophyllaceae plant Fructus Tribuli.Tap plant during fruit maturation in autumn, dry, lay fruit, removing impurity.[nature and flavor] are pungent, bitter, tepor; [return through] returns Liver Channel.[function cures mainly] suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight, antipruritic.Dizzy for having a headache, distending pain in the chest and hypochondrium, breast closes acute mastitis, cataract, rubella pruritus.[usage and dosage] takes orally: decoct soup, 6 ~ 9g.[extracts] " China's book on Chinese herbal medicine ".

Herba Schizonepetae [another name] fragrant Schizonepeta tenuifolia Briq, line shepherd's purse, Herba Schizonepetae, false Soviet Union.[source] this product is the dry aerial parts of labiate Herba Schizonepetae.Summer, season in autumn two, the flowers are in blossom to top, fringe green time tap, removing impurity, dry.[nature and flavor] are pungent, tepor.[return through] returns lung, Liver Channel.[function cures mainly] induces sweat loose wind, rash.For flu, headache, measles, rubella, skin infection from the beginning of.Parch to black treating hematochezia, metrorrhagia, puerperal blood faints.[usage and dosage] takes orally: decoct soup, 4.5 ~ 9g.[attention] exterior deficiency spontaneous perspiration, headache due to yin-deficiency avoid clothes.[extracts] " China's book on Chinese herbal medicine ".

Poria [another name] Poria, Cortex Sclerotii Poriae, Poria block, Poria, Poria.[source] this product is the dry sclerotia of On Polyporaceae Poria.Excavate more than 7 ~ JIUYUE, dig out rear removing silt, bank up after " diaphoresis ", spread out and dry in the air to dry tack free, then " diaphoresis ", after extremely now scatter and disappear in wrinkle, the large portion of internal moisture for several times repeatedly, dry in the shade, be called " Poria "; Or fresh Poria is pressed different parts cutting, dry in the shade, be called " Cortex Sclerotii Poriae " and " Poria block ".[nature and flavor] are sweet, light, flat.[return through] GUIXIN, lung, spleen, kidney channel.[function cures mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[attention] deficiency and coldness essence slides or collapse of QI person avoids clothes.[extracts] " China's book on Chinese herbal medicine ".

Flos Lonicerae [another name] Flos Lonicerae, Flos Lonicerae, little egret flower, Su Hua, JINHUA, golden rattan, Flos Lonicerae, two bud flower, Flos Lonicerae, two precious flowers.[source] this product is caprifoliaceae plant Radix Ophiopogonis, Flos Lonicerae, the Flos Lonicerae (flower that the dry flower of hair calyx Radix Ophiopogonis or hair style Radix Ophiopogonis or band are just opened.Early summer the flowers are in blossom put before gather, dry.[nature and flavor] are sweet, cold.[return through] returns lung, the heart, stomach warp.[function cures mainly] heat-clearing and toxic substances removing, wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat.[usage and dosage] takes orally: decoct soup, 6 ~ 15g.[attention] Deficiency and coldness of spleen and stomach and deficiency of vital energy skin infection pus-serum person avoid clothes.[extracts] " China's book on Chinese herbal medicine ".

Periostracum Cicadae [another name] Cicadae moves back, Periostracum Cicadae, larval moult, Cicadae shell, Zha Liao skin, cicada skin, Taurus.Exuviae shell when [source] this product is the larva emergence of cicada Cryptotympana atrata Fabr..Summer, Qiu Erji collect, and removing silt, dries.[nature and flavor] are sweet, cold.[return through] returns lung, Liver Channel.[function cures mainly] falls apart wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus.[usage and dosage] takes orally: decoct soup, 3-6g.The careful clothes of [attention] anemia of pregnant woman.[extracts] " China's book on Chinese herbal medicine ".

Cortex Dictamni [another name] Cortex Dictamni, stereotyped writing cattle, Cortex Argyreiae Seguinii Radicis, the fresh grass of sheep.[source] this product is the dry root bark of rutaceae shaggy-fruited dittany.Spring, Qiu Erji excavate root, and removing silt and rough bark, strip root bark, dry.[nature and flavor] are bitter, cold.[return through] returns spleen, stomach, urinary bladder channel.[function cures mainly] heat clearing and damp drying, removing toxic substances of dispeling the wind.For damp and hot sore, yellow fluid is dripping, eczema, rubella, scabies skin ulcer leprosy, beriberoid pyretic arthralgia, jaundice dark coloured urine.[usage and dosage] takes orally: decoct soup, 5 ~ 15g.[attention] deficiency-cold syndrome avoids clothes.Dislike the egg capsule of a mantis, Radix Platycodonis, Poria, Rhizoma Dioscoreae Septemlobae.[extracts] " China's book on Chinese herbal medicine ".

Herba Plantaginis [another name] Pie O-Fuyi, horse formal shoe, Herba Plantaginis, hold sway, mound formal shoe, Folium Fumicis Dentati, Rana limnocharis clothing, cattle is lost, victory formal shoe, wheel dish, victory formal shoe dish, clam ant grass, Rana limnocharis grass, Qian Guancao, cattle formal shoe, wild Radix Betae, Scabrous Elephantfoot Herb, Bai Guancao, pig Auricled Hedyotis Herb, meal spoon grass, Herba Lepisori Thunbergiani, five grass, yellow toad Testudinis grass, Bufo siccus grass, Gaster Sus domestica, ash pan grass, go to court careless, wheel grass, Herba Saussureae amarae, cash strings grass, cattle Radix Betae, yellow toad leaf, Rhizoma Chiritae Eburneae [source] this product is the dry herb of Plantaginaceae plant Herba Plantaginis or Plantago depressa Willd.Summer excavates, and removing silt, dries.[nature and flavor] are sweet, cold.[return through] returns liver, kidney, lung, small intestine meridian.[function cures mainly] clearing away heat and promoting diuresis, eliminates the phlegm, removing heat from blood, removing toxic substances.For edema oliguria, the puckery pain of pyretic stranguria, heat-damp in summer dysentery, phlegm-heat cough, hematemesis and epistaxis, carbuncle sore tumefacting virus.[usage and dosage] takes orally: decoct soup, 9 ~ 30g.[attention] be not if empty spermatorrhea gas consolidates person's forbidding.[extracts] " China's book on Chinese herbal medicine ".

Summary of the invention

The present invention aims to provide a kind of Chinese medicine being used for the treatment of vasodilation, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing vasodilation.

In order to achieve the above object, the present invention is by the following technical solutions:

A kind of Chinese medicine being used for the treatment of vasodilation, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Radix Arnebiae (Radix Lithospermi) 15 parts, Fructus Atriplicis Sibiricae 9 parts, Herba Schizonepetae 9 parts, 15 parts, Poria, Flos Lonicerae 15 parts, Periostracum Cicadae 9 parts, Cortex Dictamni 9 parts, Herba Plantaginis 12 parts.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

1, physical data

Outpatient service is collected and vasodilation patient 89 example of being in hospital altogether in inventor in January, 2012 ~ 2014 between year January, be divided into treatment group 46 example and matched group 43 example at random, treatment group man 20 example, female 26 example, 16 ~ 66 years old age; Matched group man 16 example, female 27 example, 18 ~ 68 years old age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.

Diagnostic criteria

Diagnostic criteria according to the meeting of national vasodilation clinical speciality: (1) skin suddenly welt occurs, can disappear behind several minutes or a few hours, generally be no more than 24 hours, occur in batch, within one day sometimes, repeatedly occur repeatedly, in cerise with light yellow, redness person's blood vessel oozes out lighter, white person produces caused by anemia by oozing out compressing blood capillary more widely, and pomphus differs in size, and large person can reach 10cm diameter or larger, (2) can there is vesicle in surface, evacuate arrangement, contiguous infringement can be merged mutually, form special circle, annular, ground figure etc., can general whole body, leave no trace after disappearing, play is had to itch, burn or stimulate pain, general acute week to be stopped paying out through a couple of days to 1 ~ 2, also recurrent exerbation is had, more than the course of disease touching 1 ~ February, what have is continuous year in year out, transfer to chronic, angioedema, there is subcutaneous tissue comparatively vegetables pine position or mucosa, large stretch of swelling in limitation transience, blur margin, do not itch, usually eyelid is involved, lip, tongue, external genitalia, hands and foot, often occur together with urticaria, if involve upper respiratory tract, throat may be blocked and threat to life.

2, test method

2.1 Therapeutic Method

The capsule that the oral the present invention for the treatment of group obtains according to embodiment 3, every day 3 times.One month course for the treatment of.

The oral chlorphenamine of matched group, each 4mg, 3 times/day; Vitamin C 0.2g, 3 times/day; Gaierqi D (vitamin D3 and calcium carbonate) 61 times/day, one month course for the treatment of.

3, criterion of therapeutical effect and therapeutic outcome

3.1 criterion of therapeutical effect

Clinic control: mucosa skin is normal, matter is soft, follows up a case by regular visits in 1 year without recurrence.

Effective: mucosa skin is normal, matter is soft, recur again after secondary contact allergy is former.

Invalid: Relapse rate shows effect.

3.2 therapeutic outcomes are in table 1.

Table 1 liang group comparitive study

Visible, the medicine that the present invention obtains can safe and effective treatment vasodilation, has promotional value.

Detailed description of the invention

In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Embodiment 1

Take: Radix Arnebiae (Radix Lithospermi) 15 grams, Fructus Atriplicis Sibiricae 9 grams, Herba Schizonepetae 9 grams, 15 grams, Poria, Flos Lonicerae 15 grams, Periostracum Cicadae 9 grams, Cortex Dictamni 9 grams, Herba Plantaginis 12 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.

Be used for the treatment of vasodilation.Oral, every bu Morning Afternoon Evening is taken for three times.

Embodiment 2

Take: Radix Arnebiae (Radix Lithospermi) 15 grams, Fructus Atriplicis Sibiricae 9 grams, Herba Schizonepetae 9 grams, 15 grams, Poria, Flos Lonicerae 15 grams, Periostracum Cicadae 9 grams, Cortex Dictamni 9 grams, Herba Plantaginis 12 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.

Be used for the treatment of vasodilation.Oral, every bu Morning Afternoon Evening is taken for three times.

Embodiment 3

Take: Radix Arnebiae (Radix Lithospermi) 15 grams, Fructus Atriplicis Sibiricae 9 grams, Herba Schizonepetae 9 grams, 15 grams, Poria, Flos Lonicerae 15 grams, Periostracum Cicadae 9 grams, Cortex Dictamni 9 grams, Herba Plantaginis 12 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.

Be used for the treatment of vasodilation.Oral, every bu Morning Afternoon Evening is taken for three times.

Claims (1)

1. one kind is used for the treatment of the Chinese medicine of vasodilation, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Radix Arnebiae (Radix Lithospermi) 15 parts, Fructus Atriplicis Sibiricae 9 parts, Herba Schizonepetae 9 parts, 15 parts, Poria, Flos Lonicerae 15 parts, Periostracum Cicadae 9 parts, Cortex Dictamni 9 parts, Herba Plantaginis 12 parts.