CN108785418A - A kind of Chinese medicine for treating angioneurotic edema - Google Patents

Abstract

The present invention relates to a kind of Chinese medicines for treating angioneurotic edema, it is prepared by the raw medicinal material of following weight proportion：15 parts of alkanet, 9 parts of tribulus terrestris, 9 parts of schizonepeta, 15 parts of Poria cocos, 15 parts of honeysuckle, 9 parts of cicada slough, 9 parts of the root bark of shaggy-fruited dittany, 12 parts of Asiatic plantain.Clinical experiments have proved that the present invention can safely and effectively treat angioneurotic edema.

Description

A kind of Chinese medicine for treating angioneurotic edema

Technical field

The present invention relates to a kind of Chinese medicines, and in particular to a kind of Chinese medicine for treating angioneurotic edema.

Background technology

Angioneurotic edema is a kind of mucous membrane hydroderma of acute local reaction type, is department of stomatology common disease.Its disease Change is apt to occur at Head And Face loose connective tissue, such as lip, tongue, cheek, palatine, can recurrent exerbation, severe one causes laryngeal edema, very To death by suffocation.The factors such as this disease and certain foods, drug, cosmetics, pollen, infection, insect bites are related.It is angioneurotic Oedema is also known as huge nettle rash, belongs to traditional Chinese medicine " urticaria ", " wheal " scope, is pented up by skin wet poison, the deficiency of blood or blood-head, multiple to feel Wind-heat forms；Or the pungent savoury of overfeeding, stomach accumulated heat feel ailment said due to cold or exposure again, make disharmony between ying and wei, damp and hot interior knot and fall ill.Disease is repeatedly Breaking-out is to cause local capillary susceptibility to increase after causing the disease to occur due to various pathogenic factors, and tube wall permeability increases, Corium and a large amount of serum of subcutaneous tissue penetrate into loose connective tissue, and western medicine can be such that capillary permeability restores just Often, it reduces the exudation of tissue fluid and helps tissue resorption diffusate, but site of pathological change capillary wall sensibility excessively increases State is there is no improving, and still in sensitive excited state, various stimulations (normal, improper) may cause its Vascular Permeability Increase, symptom occurs to form repeated relapsing again.Pass through the expelling wind and clearing away heat of Chinese medicine, removing pattogenic heat from the blood and toxic material from the body, invigorating qi for consolidating superficies and other effects It adjusts, the physiological status of local capillary is improved, to reduce its sensibility.

Medicinal material present Research involved in the present invention is as follows：

Alkanet【Alias】Gromwell root, radix macrotomiae.【Source】This product is comfrey lithospermum euchromum Royle, Asian puccoon or arnebia guttata Bunge Dry root.Spring, the excavation of two season of autumn, remove silt, dry.【Nature and flavor】It is sweet, salty, it trembles with fear.【Channel tropism】Converge to heart and liver channels.【Function master It controls】Cool blood, promoting blood circulation, promoting eruption of detoxifying.For blood-heat and toxin exuberance, atropurpureus macula, measles without adequate eruption, sore, eczema, scald.【Usage Dosage】It is for oral administration：Decoction, 5-9g.【Pay attention to】Stomach and intestine are weak, the careful clothes of lingering diarrhea person of defecating.【It takes passages】《Chinese book on Chinese herbal medicine》.

Tribulus terrestris【Alias】Tribulus terrestris, tribulus terrestris, hard puncture vine.【Source】This product is being dried to for zygophyllaceae plant puncture vine Ripe fruit.Plant is tapped when the fruit matures in the fall, is dried, fruit is laid, and removes impurity.【Nature and flavor】It is pungent, bitter, tepor；【Channel tropism】 Return liver warp.【Major function】Flat liver solution strongly fragrant, promoting blood circulation by removing wind, improving eyesight are antipruritic.For dizziness of having a headache, distending pain in the chest and hypochondrium, breast closes acute mastitis, Cataract, rubella itch.【Usage and dosage】It is for oral administration：Decoction, 6~9g.【It takes passages】《Chinese book on Chinese herbal medicine》.

Schizonepeta【Alias】Fragrant chaste tree shepherd's purse, line shepherd's purse, tetragonous bar wormwood artemisia, false Soviet Union.【Source】This product is the dry of labiate schizonepeta Dry aerial part.Summer, two season of autumn, the flowers are in blossom to top, fringe it is green when tap, remove impurity, dry.【Nature and flavor】It is pungent, tepor.【Channel tropism】 Return lung, Liver Channel.【Major function】Inducing diaphoresis relieve heat, promoting eruption.For catching a cold, have a headache, measles, rubella, sore from the beginning of.Charcoal is fried to control just Blood, uterine bleeding, postpartum anemic fainting.【Usage and dosage】It is for oral administration：Decoction, 4.5~9g.【Pay attention to】Exterior deficiency spontaneous perspiration, headache due to yin-deficiency avoid clothes.【It plucks Record】《Chinese book on Chinese herbal medicine》.

Poria cocos【Alias】Poria cocos, fuling peel, Poria cocos block, poria cocos, PORIA ALBA.【Source】This product is that Polyporaceae is true The dry sclerotia of bacterium Poria cocos.It is excavated more than 7~September, removes silt after digging out, after banking up " sweating ", spread out and dry in the air to dry tack free, " sweating " again is repeated several times to existing wrinkle, the big portion of internal moisture after scattering and disappearing, dries in the shade, referred to as " Poria cocos "；Or by fresh Poria cocos by not It with position cutting, dries in the shade, is referred to as " fuling peel " and " Poria cocos block ".【Nature and flavor】It is sweet, light, it puts down.【Channel tropism】The thoughts of returning home, lung, spleen, Kidney channel.【Major function】Clearing damp and promoting diuresis, invigorating the spleen calming heart.For oedema oliguria, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, the mind Uneasiness, insomnia of palpitating with fear.【Usage and dosage】It is for oral administration：Decoction, 9~15g.【Pay attention to】Cold of insufficiency type essence is sliding or collapse from qi deficiency person avoids clothes.【It plucks Record】《Chinese book on Chinese herbal medicine》.

Honeysuckle【Alias】Honeysuckle flowers, honeysuckle flower, little egret flower, Su Hua, golden flower, golden rattan, honeysuckle, double bud flowers, Lonicera Japonica, two Treasured flower.【Source】This product is caprifoliaceae plant honeysuckle, lonicera hypoglauca miq, Honeysuckle flower（The drying of hair calyx honeysuckle or hair style honeysuckle Bud or with the flower just opened.The flowers are in blossom puts preceding harvesting for early summer, dry.【Nature and flavor】It is sweet, it trembles with fear.【Channel tropism】Return lung, the heart, stomach.【Function It cures mainly】It is clearing heat and detoxicating, wind-heat dissipating.For carbuncle swells furunculosis, larynx numbness, erysipelas, toxic-heat and blood stasis, anemopyretic cold, warm disease heating.【With Method dosage】It is for oral administration：Decoction, 6~15g.【Pay attention to】Deficiency-cold in spleen and stomach and deficiency of vital energy sore pus-serum person avoid clothes.【It takes passages】《Chinese book on Chinese herbal medicine》.

Cicada slough【Alias】Cicada moves back, periostracum cicada, worm slough off, cicada shell, Zha Liao skins, cicada skin, Taurus.【Source】This product is Cicadidae Exuviae shell when the larva of the black grasshopper of insect sprouts wings.Summer, two season of autumn collect, and remove silt, dry.【Nature and flavor】It is sweet, it trembles with fear.【Return Through】Return lung, Liver Channel.【Major function】Relieve heat moves back screen, spasmolysis except heat, relieving sore-throat, promoting eruption.For anemopyretic cold, pharyngalgia, hoarse voice, Measles without adequate eruption, rubella itch, cataract, convulsion, lockjaw.【Usage and dosage】It is for oral administration：Decoction, 3-6g.【Pay attention to】It is pregnant The careful clothes of woman.【It takes passages】《Chinese book on Chinese herbal medicine》.

The root bark of shaggy-fruited dittany【Alias】Dittany bark, stereotyped writing ox, seguin argyreia herb, sheep fresh grass.【Source】This product is rutaceae shaggy-fruited dittany Dry root skin.Spring, two season of autumn excavate root, remove silt and tertia, strip root skin, dry.【Nature and flavor】Hardship is trembled with fear.【Channel tropism】 Returns spleen, stomach, bladder warp.【Major function】Heat-clearing and damp-drying drug, wind-dispelling removing toxic substances.For damp and hot sore, yellow water is dripping, eczema, rubella, scabies Tinea sore leprosy, beriberoid pyretic arthralgia, jaundice.【Usage and dosage】It is for oral administration：Decoction, 5~15g.【Pay attention to】Asthenia cold syndrome avoids clothes.The evil egg capsule of a mantis, Campanulaceae, Poria cocos, Bi Collettiis.【It takes passages】《Chinese book on Chinese herbal medicine》.

Asiatic plantain【Alias】Pie O-Fuyi, horse formal shoe, Chinese herbaceous peony, blocking the way, mound formal shoe, oxtongue, frog clothing, the remains of cattle, victory formal shoe, wheel Dish, victory formal shoe dish, clam ant grass, frog grass, Qian Guancao, ox formal shoe, open country beet, courage head, Bai Guancao, pig Auricled Hedyotis Herb, meal spoon be careless, seven-star Grass, five grass, yellow toad tortoise grass, toad grass, pork tripe, ash pan grass, grass of going to court, wheel grass, Herba Saussureae amarae, cash strings grass, ox Beet, yellow toad leaf, ivory-white chirita herb【Source】This product is the drying herb of plantago plant Chinese herbaceous peony or ordinary building.Summer excavates, Silt is removed, is dried.【Nature and flavor】It is sweet, it trembles with fear.【Channel tropism】Return liver, kidney, lung, small intestinl channel.【Major function】Reducing fever and causing diuresis, eliminating the phlegm are cool Blood, removing toxic substances.For oedema oliguria, puckery pain of heat gonorrhea, summer-heat and damp rush down dysentery, phlegm-heat cough, hematemesis and epistaxis, carbuncle sore tumefacting virus.【Usage and dosage】 It is for oral administration：Decoction, 9~30g.【Pay attention to】If empty involuntary emission gas does not consolidate person's disabling.【It takes passages】《Chinese book on Chinese herbal medicine》.

Invention content

The present invention is intended to provide a kind of for treating the Chinese medicine of angioneurotic edema, by select suitable medicinal material and its Proportioning, achievees the purpose that safely and effectively to cure angioneurotic edema.

In order to achieve the above object, the present invention uses following technical scheme：

A kind of Chinese medicine for treating angioneurotic edema, which is characterized in that it is by the raw medicinal material of following weight proportion It is prepared：15 parts of alkanet, 9 parts of tribulus terrestris, 9 parts of schizonepeta, 15 parts of Poria cocos, 15 parts of honeysuckle, 9 parts of cicada slough, 9 parts of the root bark of shaggy-fruited dittany, 12 parts of Asiatic plantain.

The beneficial effects of the present invention will now be described with reference to clinical experimental data：

1, general information

Outpatient service and in hospital angioneurotic edema patient 89 are collected in inventor in January, 2012 ~ 2014 year altogether between January, random point For treatment group 46 and control group 43, treatment group man 20, female 26,16~66 years old age；Control group man 16, female 27 Example, 18~68 years old age.2 groups of genders, age and course of disease comparing difference are not statistically significant, are comparable.

Diagnostic criteria

Diagnostic criteria according to national angioneurotic edema clinical speciality meeting：（1）Wheal occurs on skin suddenly, in several points Clock can subside after a few hours, be usually no more than 24 hours, occur in batch, occur repeatedly repeatedly within one day sometimes, be in cerise With it is light yellow, the exudation of red person's blood vessel is lighter, and white person is caused by wide exudation compressing capillary generates anaemia, pomphus It differs in size, big person is up to 10cm diameters or bigger；（2）Surface may occur in which that blister, evacuation arrangement, neighbouring damage can melt mutually Close, form special circle, annular, ground figure etc., can general hair whole body, leave no trace after recession, there is itching, burn or stimulate bitterly Sense, general acute stopped paying out through a couple of days to 1~2 week, also there is a recurrent exerbation, touching 1~2 month of course of disease or more, and some is year in year out not It is disconnected, switch to chronic, angioedema, subcutaneous tissue occurs compared with vegetable pine position or mucous membrane, is in limitation transience sheet swelling, side Edge is unclear, does not itch, and usually involves eyelid, lip, tongue, external genital organs, hand and foot, often occurs together with nettle rash, is exhaled if involving Road is inhaled, throat may be blocked and threat to life.

2, test method

2.1 therapy

The oral present invention for the treatment of group is according to capsule made from embodiment 3,3 times a day.The course for the treatment of one month.

Control group takes orally chlorpheniramine, each 4mg, 3 times/day；Vitamin C 0.2g, 3 times/day；61 times/day of Caltrate D, The course for the treatment of one month.

3, criterion of therapeutical effect and treatment results

3.1 criterion of therapeutical effect

Clinic control：Mucous membrane skin is normal, matter is soft, without recurrence in follow-up 1 year.

Effectively：Mucous membrane skin is normal, matter is soft, is recurred again after secondary contact allergy original.

In vain：Relapse rate breaks out.

3.2 treatment results are shown in Table 1.

1 two groups of curative effects of table compare

As it can be seen that drug produced by the present invention can safely and effectively treat angioneurotic edema, there is promotional value.

Specific implementation mode

In order to better understand with the implementation present invention, further illustrated the present invention with reference to specific embodiment.

Embodiment 1

It weighs：15 grams of alkanet, 9 grams of tribulus terrestris, 9 grams of schizonepeta, 15 grams of Poria cocos, 15 grams of honeysuckle, 9 grams of cicada slough, 9 grams of the root bark of shaggy-fruited dittany, 12 grams of Asiatic plantain；Add 8 times of amount water, decocts 1.5 hours, filtering；Filter residue adds 6 times of amount water, decocts 1 hour, filtering；Merging filtrate, 120 grams are concentrated into get the decoction of one day dosage of normal adult is met.

For treating angioneurotic edema.It is oral, it is taken three times per bu Morning Afternoon Evening.

Embodiment 2

It weighs：15 grams of alkanet, 9 grams of tribulus terrestris, 9 grams of schizonepeta, 15 grams of Poria cocos, 15 grams of honeysuckle, 9 grams of cicada slough, 9 grams of the root bark of shaggy-fruited dittany, 12 grams of Asiatic plantain；Add 10 times of amount water, decocts 2 hours, filtering；Filter residue adds 8 times of amount water, decocts 1.5 hours, filtering；Merging filtrate, Concentration, it is dry, it packs to get the powder of one day dosage of normal adult is met.

For treating angioneurotic edema.It is oral, it is taken three times per bu Morning Afternoon Evening.

Embodiment 3

It weighs：15 grams of alkanet, 9 grams of tribulus terrestris, 9 grams of schizonepeta, 15 grams of Poria cocos, 15 grams of honeysuckle, 9 grams of cicada slough, 9 grams of the root bark of shaggy-fruited dittany, 12 grams of Asiatic plantain；Add 6 times of amount water, decocts 3 times, decoct 1 hour every time, merge decoction liquor, concentrate, it is dry, capsule shells are packed into, i.e., The capsule of one day dosage of normal adult must be met.

For treating angioneurotic edema.It is oral, it is taken three times per bu Morning Afternoon Evening.

Claims (1)

1. a kind of Chinese medicine for treating angioneurotic edema, which is characterized in that it is by the bulk pharmaceutical chemicals of following weight proportion Material is prepared：15 parts of alkanet, 9 parts of tribulus terrestris, 9 parts of schizonepeta, 15 parts of Poria cocos, 15 parts of honeysuckle, 9 parts of cicada slough, the root bark of shaggy-fruited dittany 9 Part, 12 parts of Asiatic plantain.