CN107890481A - A kind of Chinese medicine for being used to treat angioneurotic edema - Google Patents

Abstract

The present invention relates to a kind of Chinese medicine for being used to treat angioneurotic edema, it is prepared by the raw medicinal material of following weight proportion：15 parts of alkanet, 9 parts of tribulus terrestris, 9 parts of schizonepeta, 15 parts of Poria cocos, 15 parts of honeysuckle, 9 parts of cicada slough, 9 parts of the root bark of shaggy-fruited dittany, 12 parts of Asiatic plantain.Clinical experiments have proved that the present invention can safely and effectively treat angioneurotic edema.

Description

A kind of Chinese medicine for being used to treat angioneurotic edema

Technical field

The present invention relates to a kind of Chinese medicine, and in particular to a kind of Chinese medicine for being used to treat angioneurotic edema.

Background technology

Angioneurotic edema is a kind of mucous membrane hydroderma of acute local reaction type, is department of stomatology common disease.Its disease Change is apt to occur at Head And Face loose connective tissue, such as lip, tongue, cheek, palatine, can recurrent exerbation, severe one causes laryngeal edema, very To death by suffocation.This sick factor such as with some foods, medicine, cosmetics, pollen, infection, insect bites is relevant.It is angioneurotic Oedema is also known as huge nettle rash, category traditional Chinese medicine " urticaria ", " wheal " category, is pented up by skin wet poison, the deficiency of blood or blood-head, multiple sense Wind-heat forms；Or the pungent savoury of overfeeding, stomach accumulated heat, ailment said due to cold or exposure is felt again, make disharmony between ying and wei, damp and hot interior knot and fall ill.Disease is repeatedly Breaking-out is due to after various pathogenic factors cause the disease to occur, to cause local capillary susceptibility to increase, the increase of tube wall permeability, Corium and a large amount of serum of hypodermis are penetrated into loose connective tissue, and western medicine can be such that capillary permeability recovers just Often, oozing out and helping tissue resorption diffusate for tissue fluid is reduced, but site of pathological change capillary wall sensitiveness excessively increases State does not improve, various to stimulate (normal, improper) cause its Vascular Permeability still in sensitive excited state Increase, symptom occur to form repeated relapsing again.Pass through the expelling wind and clearing away heat of Chinese medicine, removing pattogenic heat from the blood and toxic material from the body, invigorating qi for consolidating superficies and other effects Regulation, the physiological status of local capillary is improved, so as to reduce its sensitiveness.

Medicinal material present Research involved in the present invention is as follows：

Alkanet【Alias】Gromwell root, radix macrotomiae.【Source】This product is comfrey lithospermum euchromum Royle, Asian puccoon or arnebia guttata Bunge Dry root.Spring, the excavation of season in autumn two, remove silt, dry.【Nature and flavor】It is sweet, salty, tremble with fear.【Channel tropism】The thoughts of returning home, Liver Channel.【Function master Control】Cool blood, promoting blood circulation, promoting eruption of detoxifying.For blood-heat and toxin exuberance, atropurpureus macula, measles without adequate eruption, sore, eczema, scald.【Usage Dosage】It is for oral administration：Decoct soup, 5-9g.【Pay attention to】Stomach and intestine are weak, the stool careful clothes of lingering diarrhea person.【Take passages】《Chinese book on Chinese herbal medicine》.

Tribulus terrestris【Alias】Tribulus terrestris, tribulus terrestris, hard puncture vine.【Source】This product is dried to for zygophyllaceae plant puncture vine Ripe fruit.Plant is tapped during autumn fruit maturation, is dried, lays fruit, removes impurity.【Nature and flavor】It is pungent, bitter, tepor；【Channel tropism】 Return liver warp.【Major function】Flat liver solution strongly fragrant, promoting blood circulation by removing wind, improving eyesight are antipruritic.For dizziness of having a headache, distending pain in the chest and hypochondrium, breast closes acute mastitis, Cataract, rubella itch.【Usage and dosage】It is for oral administration：Decoct soup, 6~9g.【Take passages】《Chinese book on Chinese herbal medicine》.

Schizonepeta【Alias】Fragrant chaste tree shepherd's purse, line shepherd's purse, four rib bar wormwood artemisias, false Soviet Union.【Source】This product is the dry of labiate schizonepeta Dry aerial part.Summer, season in autumn two, the flowers are in blossom to top, fringe it is green when tap, remove impurity, dry.【Nature and flavor】It is pungent, tepor.【Channel tropism】 Return lung, Liver Channel.【Major function】Inducing diaphoresis dissipates wind, promoting eruption.For catching a cold, headache, measles, rubella, sore from the beginning of.Charcoal is fried to control just Blood, uterine bleeding, postpartum anemic fainting.【Usage and dosage】It is for oral administration：Decoct soup, 4.5~9g.【Pay attention to】Exterior deficiency spontaneous perspiration, headache due to yin-deficiency avoid clothes.【Pluck Record】《Chinese book on Chinese herbal medicine》.

Poria cocos【Alias】Poria cocos, fuling peel, Poria cocos block, poria cocos, PORIA ALBA.【Source】This product is On Polyporaceae The dry sclerotia of Poria cocos.Excavated more than 7~September, remove silt after digging out, after banking up " sweating ", spread out and dry in the air to dry tack free, then " sweating ", it is repeated several times to existing wrinkle, the big portion of internal moisture after scattering and disappearing, dries in the shade, is referred to as " Poria cocos "；Or by fresh Poria cocos by difference Position cutting, dries in the shade, and is referred to as " fuling peel " and " Poria cocos block ".【Nature and flavor】It is sweet, light, put down.【Channel tropism】The thoughts of returning home, lung, spleen, kidney Through.【Major function】Clearing damp and promoting diuresis, invigorating the spleen calming heart.For oedema oliguria, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, the mind is not Peace, insomnia of palpitating with fear.【Usage and dosage】It is for oral administration：Decoct soup, 9~15g.【Pay attention to】Cold of insufficiency type essence cunning or collapse from qi deficiency person avoid clothes.【Take passages】 《Chinese book on Chinese herbal medicine》.

Honeysuckle【Alias】Honeysuckle flowers, honeysuckle flower, little egret flower, Su Hua, golden flower, golden rattan, honeysuckle, double bud flowers, two flowers, two Treasured flower.【Source】This product is caprifoliaceae plant honeysuckle, lonicera hypoglauca miq, Honeysuckle flower（Hair calyx honeysuckle or the drying of hair style honeysuckle Bud or with the flower just opened.The flowers are in blossom puts preceding harvesting for early summer, dries.【Nature and flavor】It is sweet, tremble with fear.【Channel tropism】Return lung, the heart, stomach.【Function Cure mainly】It is clearing heat and detoxicating, wind-heat dissipating.For carbuncle swells furunculosis, larynx numbness, erysipelas, toxic-heat and blood stasis, anemopyretic cold, warm disease heating.【With Method dosage】It is for oral administration：Decoct soup, 6~15g.【Pay attention to】Deficiency-cold in spleen and stomach and deficiency of vital energy sore pus-serum person avoid clothes.【Take passages】《Chinese book on Chinese herbal medicine》.

Cicada slough【Alias】Cicada moves back, periostracum cicada, worm slough off, cicada shell, Zha Liao skins, cicada skin, Taurus.【Source】This product is Cicadidae elder brother Exuviae shell when the larva of the black grasshopper of worm sprouts wings.Summer, season in autumn two collect, and remove silt, dry.【Nature and flavor】It is sweet, tremble with fear.【Channel tropism】 Return lung, Liver Channel.【Major function】Wind is dissipated except heat, relieving sore-throat, promoting eruption, moves back screen, spasmolysis.It is mute for anemopyretic cold, pharyngalgia, sound, measles It is impermeable, rubella itch, cataract, convulsion, lockjaw.【Usage and dosage】It is for oral administration：Decoct soup, 3-6g.【Pay attention to】Pregnant woman is careful Clothes.【Take passages】《Chinese book on Chinese herbal medicine》.

The root bark of shaggy-fruited dittany【Alias】Dittany bark, stereotyped writing ox, seguin argyreia herb, sheep fresh grass.【Source】This product is rutaceae shaggy-fruited dittany Dry root skin.Spring, season in autumn two excavation root, remove silt and tertia, strip root skin, dry.【Nature and flavor】Hardship, tremble with fear.【Channel tropism】Return Spleen, stomach, bladder warp.【Major function】Heat-clearing and damp-drying drug, wind-dispelling removing toxic substances.For damp and hot sore, yellow water is dripping, eczema, rubella, mange Sore leprosy, beriberoid pyretic arthralgia, jaundice.【Usage and dosage】It is for oral administration：Decoct soup, 5~15g.【Pay attention to】Asthenia cold syndrome avoids clothes.Dislike the egg capsule of a mantis, tangerine Stalk, Poria cocos, Bi Collettiis.【Take passages】《Chinese book on Chinese herbal medicine》.

Asiatic plantain【Alias】Pie O-Fuyi, horse formal shoe, Chinese herbaceous peony, blocking the way, mound formal shoe, oxtongue, frog clothing, ox lose, victory formal shoe, wheel dish, Win formal shoe dish, clam ant grass, frog grass, Qian Guancao, ox formal shoe, wild beet, courage head, Bai Guancao, pig Auricled Hedyotis Herb, meal spoon are careless, seven-star are careless, five Root is careless, yellow toad tortoise grass, toad grass, pork tripe, ash pan grass, grass of going to court, wheel grass, Herba Saussureae amarae, cash strings grass, ox beet, Yellow toad leaf, ivory-white chirita herb【Source】This product is the drying herb of plantago plant Chinese herbaceous peony or ordinary building.Summer excavates, and removes mud Sand, dry.【Nature and flavor】It is sweet, tremble with fear.【Channel tropism】Return liver, kidney, lung, small intestinl channel.【Major function】Reducing fever and causing diuresis, eliminating the phlegm, cool blood, solution Poison.For oedema oliguria, puckery pain of heat gonorrhea, summer-heat and damp rush down dysentery, phlegm-heat cough, hematemesis and epistaxis, carbuncle sore tumefacting virus.【Usage and dosage】It is for oral administration： Decoct soup, 9~30g.【Pay attention to】If empty involuntary emission gas does not consolidate person's disabling.【Take passages】《Chinese book on Chinese herbal medicine》.

The content of the invention

The present invention is intended to provide a kind of be used to treat the Chinese medicine of angioneurotic edema, by select suitable medicinal material and its Proportioning, reach the purpose for safely and effectively curing angioneurotic edema.

In order to achieve the above object, the present invention uses following technical scheme：

A kind of Chinese medicine for being used to treat angioneurotic edema, it is characterised in that it is by the raw medicinal material of following weight proportion It is prepared：15 parts of alkanet, 9 parts of tribulus terrestris, 9 parts of schizonepeta, 15 parts of Poria cocos, 15 parts of honeysuckle, 9 parts of cicada slough, 9 parts of the root bark of shaggy-fruited dittany, 12 parts of Asiatic plantain.

The beneficial effects of the present invention will now be described with reference to clinical experimental data：

1st, general information

Outpatient service and in hospital angioneurotic edema patient 89 are collected in inventor in January, 2012 ~ 2014 year altogether between January, random point For treatment group 46 and control group 43, treatment group man 20, female 26,16~66 years old age；Control group man 16, female 27 Example, 18~68 years old age.2 groups of sexes, age and course of disease comparing difference are not statistically significant, have comparativity.

Diagnostic criteria

Diagnostic criteria according to national angioneurotic edema clinical speciality meeting：（1）Wheal occurs on skin suddenly, in several points Clock can disappear after a few hours, be usually no more than 24 hours, occur in batch, occur repeatedly repeatedly, in cerise within one day sometimes With it is light yellow, red person's blood vessel oozes out relatively light, and white person is oozed out caused by compressing capillary produces anaemia by wide, pomphus Differ in size, big person is up to 10cm diameters or bigger；（2）Surface may occur in which blister, evacuation arrangement, and neighbouring infringement can melt mutually Close, form special circle, annular, ground figure etc., can general hair whole body, leave no trace after regression, have itching, burn or stimulates bitterly Sense, general acute stopped paying out through a couple of days to 1~2 week, also there is a recurrent exerbation, touching more than 1~2 month of the course of disease, and some is year in year out not It is disconnected, switch to chronic, angioedema, hypodermis occurs compared with vegetable pine position or mucous membrane, in limitation transience sheet swelling, side Edge is unclear, does not itch, and generally involves eyelid, lip, tongue, external genital organs, hand and foot, often occurs together with nettle rash, is exhaled if involving Road is inhaled, throat may be blocked and threat to life.

2nd, test method

2.1 treatment method

The oral present invention for the treatment of group is according to capsule made from embodiment 3,3 times a day.The course for the treatment of one month.

The oral chlorpheniramine of control group, each 4mg, 3 times/day；Vitamin C 0.2g, 3 times/day；61 times/day of Caltrate D, The course for the treatment of one month.

3rd, criterion of therapeutical effect and treatment results

3.1 criterion of therapeutical effect

Clinic control：Mucous membrane skin is normal, matter is soft, without recurrence in follow-up 1 year.

Effectively：Mucous membrane skin is normal, matter is soft, is recurred again after secondary contact allergy original.

It is invalid：Relapse rate breaks out.

3.2 treatment results are shown in Table 1.

1 two groups of curative effects of table compare

It can be seen that medicine produced by the present invention can safely and effectively treat angioneurotic edema, there is promotional value.

Embodiment

In order to more fully understand and implement the present invention, the present invention is further illustrated with reference to specific embodiment.

Embodiment 1

Weigh：15 grams of alkanet, 9 grams of tribulus terrestris, 9 grams of schizonepeta, 15 grams of Poria cocos, 15 grams of honeysuckle, 9 grams of cicada slough, 9 grams of the root bark of shaggy-fruited dittany, 12 grams of Asiatic plantain；Add 8 times of amount water, decoct 1.5 hours, filtering；Filter residue adds 6 times of amount water, decocts 1 hour, filtering；Merging filtrate, 120 grams are concentrated into, produces the decoction for meeting one day dosage of normal adult.

For treating angioneurotic edema.Orally, taken three times per bu Morning Afternoon Evening.

Embodiment 2

Weigh：15 grams of alkanet, 9 grams of tribulus terrestris, 9 grams of schizonepeta, 15 grams of Poria cocos, 15 grams of honeysuckle, 9 grams of cicada slough, 9 grams of the root bark of shaggy-fruited dittany, 12 grams of Asiatic plantain；Add 10 times of amount water, decoct 2 hours, filtering；Filter residue adds 8 times of amount water, decocts 1.5 hours, filtering；Merging filtrate, Concentration, dry, packaging, produce the powder for meeting one day dosage of normal adult.

For treating angioneurotic edema.Orally, taken three times per bu Morning Afternoon Evening.

Embodiment 3

Weigh：15 grams of alkanet, 9 grams of tribulus terrestris, 9 grams of schizonepeta, 15 grams of Poria cocos, 15 grams of honeysuckle, 9 grams of cicada slough, 9 grams of the root bark of shaggy-fruited dittany, 12 grams of Asiatic plantain；Add 6 times of amount water, decoct 3 times, decoct 1 hour every time, merge decoction liquor, concentrate, dry, load capsule shells, i.e., The capsule of one day dosage of normal adult must be met.

For treating angioneurotic edema.Orally, taken three times per bu Morning Afternoon Evening.

Claims (1)

1. a kind of Chinese medicine for being used to treat angioneurotic edema, it is characterised in that it is by the bulk drug of following weight proportion Material is prepared：15 parts of alkanet, 9 parts of tribulus terrestris, 9 parts of schizonepeta, 15 parts of Poria cocos, 15 parts of honeysuckle, 9 parts of cicada slough, the root bark of shaggy-fruited dittany 9 Part, 12 parts of Asiatic plantain.