CN104824651B - The krill oil microcapsule and its preparation technology of a kind of high content - Google Patents
The krill oil microcapsule and its preparation technology of a kind of high content Download PDFInfo
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- CN104824651B CN104824651B CN201510266427.0A CN201510266427A CN104824651B CN 104824651 B CN104824651 B CN 104824651B CN 201510266427 A CN201510266427 A CN 201510266427A CN 104824651 B CN104824651 B CN 104824651B
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- krill oil
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- 229940106134 krill oil Drugs 0.000 title claims abstract description 49
- 239000003094 microcapsule Substances 0.000 title claims abstract description 36
- 238000005516 engineering process Methods 0.000 title claims abstract description 10
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 34
- 239000003921 oil Substances 0.000 claims abstract description 33
- 229920001285 xanthan gum Polymers 0.000 claims abstract description 13
- RQFQJYYMBWVMQG-IXDPLRRUSA-N chitotriose Chemical compound O[C@@H]1[C@@H](N)[C@H](O)O[C@H](CO)[C@H]1O[C@H]1[C@H](N)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)N)[C@@H](CO)O1 RQFQJYYMBWVMQG-IXDPLRRUSA-N 0.000 claims abstract description 12
- 239000004530 micro-emulsion Substances 0.000 claims abstract description 12
- 239000003963 antioxidant agent Substances 0.000 claims abstract description 11
- 230000003078 antioxidant effect Effects 0.000 claims abstract description 10
- 229920002472 Starch Polymers 0.000 claims abstract description 9
- 235000013808 oxidized starch Nutrition 0.000 claims abstract description 9
- 239000001254 oxidized starch Substances 0.000 claims abstract description 9
- 239000008107 starch Substances 0.000 claims abstract description 9
- 235000019698 starch Nutrition 0.000 claims abstract description 9
- 239000002270 dispersing agent Substances 0.000 claims abstract description 6
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 6
- 238000003756 stirring Methods 0.000 claims description 10
- 235000006708 antioxidants Nutrition 0.000 claims description 8
- 238000002156 mixing Methods 0.000 claims description 8
- 238000007664 blowing Methods 0.000 claims description 5
- 238000009413 insulation Methods 0.000 claims description 5
- 239000007921 spray Substances 0.000 claims description 5
- 239000000463 material Substances 0.000 abstract description 20
- 238000000034 method Methods 0.000 abstract description 11
- 150000003904 phospholipids Chemical class 0.000 abstract description 9
- 230000036541 health Effects 0.000 abstract description 5
- 230000008569 process Effects 0.000 abstract description 5
- 239000002253 acid Substances 0.000 abstract description 4
- 235000001497 healthy food Nutrition 0.000 abstract description 4
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 abstract description 3
- 235000013365 dairy product Nutrition 0.000 abstract description 3
- 238000011031 large-scale manufacturing process Methods 0.000 abstract description 3
- 239000000203 mixture Substances 0.000 abstract description 2
- 235000019198 oils Nutrition 0.000 description 26
- BGNXCDMCOKJUMV-UHFFFAOYSA-N Tert-Butylhydroquinone Chemical compound CC(C)(C)C1=CC(O)=CC=C1O BGNXCDMCOKJUMV-UHFFFAOYSA-N 0.000 description 12
- 241000239366 Euphausiacea Species 0.000 description 9
- 239000011162 core material Substances 0.000 description 8
- 239000000243 solution Substances 0.000 description 7
- 239000004250 tert-Butylhydroquinone Substances 0.000 description 6
- 235000019281 tert-butylhydroquinone Nutrition 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 239000011734 sodium Substances 0.000 description 5
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 4
- 229920001661 Chitosan Polymers 0.000 description 4
- ZTHYODDOHIVTJV-UHFFFAOYSA-N Propyl gallate Chemical compound CCCOC(=O)C1=CC(O)=C(O)C(O)=C1 ZTHYODDOHIVTJV-UHFFFAOYSA-N 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 239000002775 capsule Substances 0.000 description 3
- 230000018109 developmental process Effects 0.000 description 3
- 229920001542 oligosaccharide Polymers 0.000 description 3
- 150000002482 oligosaccharides Chemical class 0.000 description 3
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 2
- 241000238557 Decapoda Species 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- 235000010323 ascorbic acid Nutrition 0.000 description 2
- 239000011668 ascorbic acid Substances 0.000 description 2
- 229960005070 ascorbic acid Drugs 0.000 description 2
- OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical class CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 239000008101 lactose Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 235000010388 propyl gallate Nutrition 0.000 description 2
- 239000000473 propyl gallate Substances 0.000 description 2
- 229940075579 propyl gallate Drugs 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 238000001694 spray drying Methods 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 230000032258 transport Effects 0.000 description 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 description 1
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 208000024827 Alzheimer disease Diseases 0.000 description 1
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 206010008111 Cerebral haemorrhage Diseases 0.000 description 1
- CIWBSHSKHKDKBQ-DUZGATOHSA-N D-araboascorbic acid Natural products OC[C@@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-DUZGATOHSA-N 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 201000005569 Gout Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 201000001429 Intracranial Thrombosis Diseases 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 206010039966 Senile dementia Diseases 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000001785 acacia senegal l. willd gum Substances 0.000 description 1
- 239000003463 adsorbent Substances 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 239000012670 alkaline solution Substances 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000002929 anti-fatigue Effects 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 235000013793 astaxanthin Nutrition 0.000 description 1
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 description 1
- 229940022405 astaxanthin Drugs 0.000 description 1
- 239000001168 astaxanthin Substances 0.000 description 1
- 238000000889 atomisation Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 230000004641 brain development Effects 0.000 description 1
- 235000019282 butylated hydroxyanisole Nutrition 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 235000010350 erythorbic acid Nutrition 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 235000021323 fish oil Nutrition 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229940094952 green tea extract Drugs 0.000 description 1
- 235000020688 green tea extract Nutrition 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 210000001525 retina Anatomy 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 235000015067 sauces Nutrition 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 235000010378 sodium ascorbate Nutrition 0.000 description 1
- PPASLZSBLFJQEF-RKJRWTFHSA-M sodium ascorbate Substances [Na+].OC[C@@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RKJRWTFHSA-M 0.000 description 1
- 229960005055 sodium ascorbate Drugs 0.000 description 1
- PPASLZSBLFJQEF-RXSVEWSESA-M sodium-L-ascorbate Chemical compound [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RXSVEWSESA-M 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- -1 sucrose fatty ester Chemical class 0.000 description 1
- 150000003445 sucroses Chemical class 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 235000013616 tea Nutrition 0.000 description 1
- DINKXUCRJBUQAZ-UHFFFAOYSA-N tert-butyl 5-bromopyridine-3-carboxylate Chemical compound CC(C)(C)OC(=O)C1=CN=CC(Br)=C1 DINKXUCRJBUQAZ-UHFFFAOYSA-N 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
- A23D9/02—Other edible oils or fats, e.g. shortenings, cooking oils characterised by the production or working-up
- A23D9/04—Working-up
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The present invention relates to the krill oil microcapsule and its preparation technology of a kind of high content, the technique adds a small amount of xanthans with krill oil, micropore starch as core in oil phase；With chitosan oligosaccharide, oxidized starch as wall material, mix in proportion with oil phase antioxidant, water phase antioxidant, emulsifying agent, dispersant etc., be made microemulsion, then spray-dried be made krill oil microcapsules pulvis.The content of phospholipid of gained krill oil microcapsule product is 10 30%, maintain bioactivity, improve krill oil to the stability of photo-thermal, soda acid etc., in cold water also have good dissolubility, more conducively process, transport and store, substantially increase security, mobility and the water solubility of product, the range of application of krill oil is expanded, is excellent healthy food material, be widely applied to dairy products, drink, health products, baking, tablet etc..Prepare that krill oil microcapsules pulvis yield is high using the technique, content of phospholipid is high in product, is suitable to largely prepare krill oil microcapsules pulvis, realizes serialization large-scale production.
Description
Technical field
The present invention relates to the production technical field of krill oil microcapsule, and in particular to a kind of krill oil microcapsule of high content
And its preparation technology.
Background technology
Krill is one of the biology of highest containing protein having been found that, protein content up to 50 percent with
On, but also be that the Nature is presented to the day of the mankind containing amino acid and vitamin A necessary to extremely abundant tissue
Right healthy food, contains the irreplaceable effect of other food.
The phosphatide mating type Omega-3 that antarctic krill oil contains（Including EPA and DHA）, than the triglyceride type in fish oil
Omega-3 is easier to absorb, and is effective source of DHA and EPA.In addition, krill oil also contains natural --- shrimp is blue or green
Element.Astaxanthin also has protective effect except energy prevention of cardiovascular disease to retina and central nervous system.The health care of krill oil
Function includes：Reduction blood fat, cholesterol, prevention cerebral hemorrhage, cerebral thrombus；Reduce blood viscosity, stimulate circulation, prevent
Hypertension；Brain tonic and intelligence development, active thinking prevents senile dementia；Protection neuron membrane, strengthens notice and memory, reason
Xie Li；Promote Fetal Brain development；It is antifatigue；Alleviate gout and rheumatoid arthritis；Reduce stiff, swelling and Tender Joint；
Green Tea Extract, delaying aging；It is obviously improved wrinkle of skin depth；Support vision health；Improve women's premenstrual molimen symptom etc..
In China, the exploitation to krill resource is still in starting stage, in China's patent protection, krill oil extract
The patent of aspect accounts for main body, and the patent of krill oil microcapsual powder or pulverulent product is less, and microcapsule powder krill oil content of phospholipid
It is relatively low, therefore limit the range of application of krill oil.The weight of national marine development strategy deposit is had become due to krill
Want one of content, thus accelerate the technical research of krill development of resources, prepare the krill oil microcapsule powder of high content, expand
The range of application of krill oil, realizes the industrialization production to krill resource, is significant.
Spray drying process is that core material is dispersed in the solution containing capsule material, is well mixed, then by aerodynamic atomization
Dry, solvent is evaporated rapidly, wall material solidification coats core material and forms micro-capsule wherein.
In the selection of microcapsule wall material, traditional more such as gelatin of wall material application, casein sodium, Arabic gum, but it is past
It is relatively low toward the microcapsule product content for obtaining, it is unsuitable for the preparation of high content product.In addition, the product flowing of protide wall material
Property, it is water-soluble relatively poor, particularly disadvantageous in cold water diffusion, release property is poor, the strong influence using effect of product.Cause
This, prepares the krill oil microcapsules pulvis of high content, select suitable microcapsule wall material be to microcapsules technology it is the most key,
It directly determines microencapsulation embedding effect, product content and release characteristics.
The content of the invention
A kind of technical problems to be solved by the invention, aiming at the deficiencies in the prior art, there is provided krill of high content
Oil microcapsule and its preparation technology.The technique adds a small amount of xanthans with krill oil, micropore starch as core in oil phase；With
Chitosan oligosaccharide, oxidized starch are wall material, are mixed in proportion with oil phase antioxidant, water phase antioxidant, emulsifying agent, dispersant etc.,
Microemulsion is made, then spray-dried is made krill oil microcapsules pulvis.The content of phospholipid of gained krill oil microcapsule product is
10-30%, maintains bioactivity, and improve krill oil also has well to the stability of photo-thermal, soda acid etc., in cold water
Dissolubility, more conducively processes, transports and stores, and substantially increases security, mobility and the water solubility of product, expands phosphorus
The range of application of shrimp sauce, is excellent healthy food material, is widely applied to dairy products, drink, health products, baking, tablet etc..
Prepare that krill oil microcapsules pulvis yield is high using the technique, content of phospholipid is high in product, is suitable to largely prepare the micro- glue of krill oil
Capsule pulvis, realizes serialization large-scale production.
The krill oil microcapsule and its preparation technology of a kind of high content, it is characterised in that：Described krill oil microcapsule by
Core, wall material, oil phase antioxidant, water phase antioxidant, emulsifying agent, dispersant composition,
Described wall material is chitosan oligosaccharide, oxidized starch and a small amount of xanthans；
Described core is krill oil, micropore starch；
Described dispersant is the one kind or any two or three in sucrose, glucose, trehalose, lactose；
Described oil phase antioxidant is natural VE, butylated hydroxy anisole（BHA）, butyl hydroxy toluene
（BHT）, propylgallate（PG）, TBHQ（TBHQ）In one kind or any two or three；
Described water phase antioxidant is Tea Polyphenols, ascorbic acid, EDTA-Na, sodium ascorbate, D-araboascorbic acid sodium
In one kind or any two or three；
Described emulsifying agent is the one kind or any two or three in monoglyceride, sucrose fatty ester, lecithin.
Preferably, the preparation technology of the krill oil microcapsule of a kind of high content as described above, it is characterised in that including such as
Lower step：
（1）Stir molten during the chitosan oligosaccharide of the oxidized starch of 10-60%, 1-5% is added into 60~100 DEG C, the water of 50-90%
Solution, the emulsifying agent of the dispersant of 0.1-6%, the water phase antioxidant of 0.1-6%, 0.1-6% is added in the solution for having dissolved,
Stirring is allowed to well mixed, 50~70 DEG C of insulation stand for standby use, and water phase is obtained；
（2）The krill oil of 10-80%, the micropore starch of 1-10%, the xanthans of 0.1-0.25%, 0.1~1% oil phase are resisted
Oxidant mixes, 60~90 DEG C of 3~10min of oil bath, and oil phase is obtained；
（3）The water phase and oil phase that will have been dissolved are while blowing, controls flow, by water phase respectively：Oil phase=5-1:1（Quality
Than）With pipeline cutter on-line mixing, 10000~16000 revs/min of 5~10min of revolution, 19000~28000 rev/min 5~
8min, then homogeneous under 30~50Mpa again, is obtained microemulsion；
（4）Microemulsion is spray-dried, spray tower intake air temperature is controlled in 150~190 DEG C, air outlet temperature control
System is in 60~90 DEG C, 1000~1400r/min of atomizer rotating speed；Krill oil microcapsule is obtained.
Advantageous Effects of the invention are：
1st, with chitosan oligosaccharide as wall material.In patent document both domestic and external, using shitosan as the more of wall material, using chitosan oligosaccharide
For wall material is little, but chitosan oligosaccharide is compared with shitosan, more advantage.Chitosan oligosaccharide is that the degree of polymerization after degradation of chitosan is 2-10
Product.Shitosan is water insoluble and aqueous slkali, dissolves in most of low concentration inorganic acids or organic acid, therefore as wall material,
Must generally be dissolved in acetic acid and use, and chitosan oligosaccharide is water-soluble, acid and alkaline solution, using more extensive.Chitosan oligosaccharide has more preferable
Moisture absorption, moisturizing and film forming, the characteristic for good biocompatibility and easily absorbing, its filming performance is to make the micro- glue of krill oil
The ideal material of capsule, reaches the effect of slow-release controlled-release core, keeps krill oil bioactivity, and chitosan oligosaccharide molecular weight is small, 99% with
On can be absorbed, can be widely applied to food, medicine, cosmetics, agricultural and feedstuff industry.
2nd, use micropore starch as core and adsorbent in technical solution of the present invention, the function of sheltering can be played, prevent
Only krill oil is oxidized, and is used cooperatively with oxidized starch, xanthans, product is reached highest bioactivity, improves storage phase.
3rd, oil phase with the addition of a small amount of xanthans as wall material in this technique, and xanthans has unique strong anti-oxidation
Can, it is highly beneficial for oxidizable krill oil core.In addition, xanthans has larger viscosity, special shearing
Can be conducive to the stabilization of emulsion with high emulsibility, the compactness of wall material and the oxidation resistance of product can be strengthened.Xanthans
Droplet for forming larger in spray-drying process is highly beneficial, can obtain larger particles and improve the stream of microscapsule powder
Dynamic property.
4th, krill oil microcapsule preparation process of the present invention, products obtained therefrom maintains bioactivity, improves krill oil
Stability to photo-thermal, soda acid etc., also there is good dissolubility in cold water, more conducively process, transport and store, carry significantly
The high security of product, mobility and water solubility, expand the range of application of krill oil, are excellent healthy food materials,
It is widely applied to dairy products, drink, health products, baking, tablet etc..Krill oil microcapsules pulvis yield is prepared using the technique
Height, content of phospholipid is high in product, is suitable to largely prepare krill oil microcapsules pulvis, realizes serialization large-scale production.
Specific embodiment
For the technical characterstic for illustrating the present invention program can be understood, with reference to specific embodiment, the present invention is illustrated.
But protection scope of the present invention is not limited to these embodiments.It is every equal without departing substantially from the change of present inventive concept or equivalent substitute
It is included within protection scope of the present invention.
Embodiment 1
（1）The oxidized starch of 35kg, 3kg chitosan oligosaccharides are added to stirring and dissolving in 90 DEG C of 210kg water, by 5kg marine algas
Sugar, 5kg EDTA-Na, 0.1kg monoglycerides are added in the solution for having dissolved, and stirring is allowed to well mixed, 50~70 DEG C of insulations
Stand for standby use, is obtained water phase；
（2）By 65kg krill oils（Content of phospholipid is 40%）, 5kg micropore starch, 0.2kg xanthans, 0.1kg naturally tie up life
Plain E, 0.1kg TBHQ（TBHQ）Mixing, 90 DEG C of 3~10min of oil bath are obtained oil phase.
（3）The water phase and oil phase that will have been dissolved are while blowing, controls flow, by water phase respectively：Oil phase=4:1（Mass ratio）
With pipeline cutter on-line mixing, 10000~16000 revs/min of 5~10min of revolution, 19000~28000 revs/min of 5~8min,
Then homogeneous under 30~50Mpa again, is obtained microemulsion.
（4）Microemulsion is spray-dried, spray tower intake air temperature is controlled in 150~190 DEG C, air outlet temperature control
System is in 60~90 DEG C, 1000~1400r/min of atomizer rotating speed；Krill oil microcapsule is obtained.Phosphatide contains in the microcapsule product
Amount is not less than 20%.
Embodiment 2
（1）The oxidized starch of 25kg, 2kg chitosan oligosaccharides are added to stirring and dissolving in 90 DEG C of 210kg water, by 5kg marine algas
Sugar, 5kg EDTA-Na, 0.1kg monoglycerides are added in the solution for having dissolved, and stirring is allowed to well mixed, 50~70 DEG C of insulations
Stand for standby use, is obtained water phase；
（2）By 80kg krill oils（Content of phospholipid is 40%）, 5kg micropore starch, 0.2kg xanthans, 0.1kg naturally tie up life
Plain E, 0.1kg TBHQ（TBHQ）Mixing, 90 DEG C of 3~10min of oil bath are obtained oil phase.
（3）The water phase and oil phase that will have been dissolved are while blowing, controls flow, by water phase respectively：Oil phase=3:1（Mass ratio）
With pipeline cutter on-line mixing, 10000~16000 revs/min of 5~10min of revolution, 19000~28000 revs/min of 5~8min,
Then homogeneous under 30~50Mpa again, is obtained microemulsion.
（4）Microemulsion is spray-dried, spray tower intake air temperature is controlled in 150~190 DEG C, air outlet temperature control
System is in 60~90 DEG C, 1000~1400r/min of atomizer rotating speed；Krill oil microcapsule is obtained.Phosphatide contains in the microcapsule product
Amount is not less than 25%.
Embodiment 3
（1）The oxidized starch of 20kg, 1kg chitosan oligosaccharides are added to stirring and dissolving in 90 DEG C of 420kg water, by 5kg lactose,
5kg ascorbic acid, 0.2kg sucrose esters are added in the solution for having dissolved, and stirring is allowed to well mixed, and 50~70 DEG C of insulations stand
It is standby, water phase is obtained；
（2）By 150kg krill oils（Content of phospholipid is 40%）, 10kg micropore starch, 0.4kg xanthans, 0.2kg naturally tie up
Raw element E, 0.2kg propylgallate（PG）Mixing, 90 DEG C of 3~10min of oil bath are obtained oil phase.
（3）The water phase and oil phase that will have been dissolved are while blowing, controls flow, by water phase respectively：Oil phase=3:1（Mass ratio）
With pipeline cutter on-line mixing, 10000~16000 revs/min of 5~10min of revolution, 19000~28000 revs/min of 5~8min,
Then homogeneous under 30~50Mpa again, is obtained microemulsion.
（4）Microemulsion is spray-dried, spray tower intake air temperature is controlled in 150~190 DEG C, air outlet temperature control
System is in 60~90 DEG C, 1000~1400r/min of atomizer rotating speed；Krill oil microcapsule is obtained.Phosphatide contains in the microcapsule product
Amount is not less than 30%.
Claims (1)
1. the preparation technology of the krill oil microcapsule of a kind of high content, it is characterised in that comprise the following steps：
（1）Stirring and dissolving during the chitosan oligosaccharide of the oxidized starch of 10-60%, 1-5% is added into 60~100 DEG C, the water of 50-90%, will
The dispersant of 0.1-6%, the water phase antioxidant of 0.1-6%, the emulsifying agent of 0.1-6% are added in the solution for having dissolved, and stirring makes
Well mixed, 50~70 DEG C of insulation stand for standby use are obtained water phase；
（2）The krill oil of 10-80%, the micropore starch of 1-10%, the xanthans of 0.1-0.25%, 0.1~1% oil phase is anti-oxidant
Agent mixes, 60~90 DEG C of 3~10min of oil bath, and oil phase is obtained；
（3）The water phase and oil phase that will have been dissolved are while blowing, controls flow, water phase, oil phase 5-1 in mass ratio respectively:1 uses pipeline
Cutter on-line mixing, 10000~16000 revs/min of 5~10min of revolution, 19000~28000 revs/min of 5~8min, Ran Houzai
Homogeneous under 30~50Mpa, is obtained microemulsion；
（4）Microemulsion is spray-dried, at 150~190 DEG C, air outlet temperature control exists the control of spray tower intake air temperature
60~90 DEG C, 1000~1400r/min of atomizer rotating speed is obtained krill oil microcapsule.
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