CN104824651A - High-content krill oil microcapsules and preparation technology thereof - Google Patents
High-content krill oil microcapsules and preparation technology thereof Download PDFInfo
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- CN104824651A CN104824651A CN201510266427.0A CN201510266427A CN104824651A CN 104824651 A CN104824651 A CN 104824651A CN 201510266427 A CN201510266427 A CN 201510266427A CN 104824651 A CN104824651 A CN 104824651A
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- krill oil
- oil
- krill
- aqueous phase
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- 229940106134 krill oil Drugs 0.000 title claims abstract description 58
- 239000003094 microcapsule Substances 0.000 title claims abstract description 40
- 238000005516 engineering process Methods 0.000 title claims abstract description 14
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 239000000463 material Substances 0.000 claims abstract description 21
- 239000003963 antioxidant agent Substances 0.000 claims abstract description 16
- 230000003078 antioxidant effect Effects 0.000 claims abstract description 16
- RQFQJYYMBWVMQG-IXDPLRRUSA-N chitotriose Chemical compound O[C@@H]1[C@@H](N)[C@H](O)O[C@H](CO)[C@H]1O[C@H]1[C@H](N)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)N)[C@@H](CO)O1 RQFQJYYMBWVMQG-IXDPLRRUSA-N 0.000 claims abstract description 16
- 229920001285 xanthan gum Polymers 0.000 claims abstract description 14
- 239000004530 micro-emulsion Substances 0.000 claims abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 12
- 238000002156 mixing Methods 0.000 claims abstract description 11
- 229920002472 Starch Polymers 0.000 claims abstract description 10
- 235000013808 oxidized starch Nutrition 0.000 claims abstract description 10
- 239000001254 oxidized starch Substances 0.000 claims abstract description 10
- 239000008107 starch Substances 0.000 claims abstract description 10
- 235000019698 starch Nutrition 0.000 claims abstract description 10
- 239000002270 dispersing agent Substances 0.000 claims abstract description 8
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 8
- 239000012071 phase Substances 0.000 claims description 24
- 239000008346 aqueous phase Substances 0.000 claims description 22
- BGNXCDMCOKJUMV-UHFFFAOYSA-N Tert-Butylhydroquinone Chemical compound CC(C)(C)C1=CC(O)=CC=C1O BGNXCDMCOKJUMV-UHFFFAOYSA-N 0.000 claims description 16
- 235000006708 antioxidants Nutrition 0.000 claims description 14
- ZTHYODDOHIVTJV-UHFFFAOYSA-N Propyl gallate Chemical compound CCCOC(=O)C1=CC(O)=C(O)C(O)=C1 ZTHYODDOHIVTJV-UHFFFAOYSA-N 0.000 claims description 12
- 238000003756 stirring Methods 0.000 claims description 10
- 239000004250 tert-Butylhydroquinone Substances 0.000 claims description 8
- 235000019281 tert-butylhydroquinone Nutrition 0.000 claims description 8
- 239000011734 sodium Substances 0.000 claims description 7
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 6
- 235000010388 propyl gallate Nutrition 0.000 claims description 6
- 229930006000 Sucrose Natural products 0.000 claims description 5
- 238000007664 blowing Methods 0.000 claims description 5
- 238000009413 insulation Methods 0.000 claims description 5
- 239000007921 spray Substances 0.000 claims description 5
- 238000005507 spraying Methods 0.000 claims description 5
- 239000005720 sucrose Substances 0.000 claims description 5
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims description 4
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 claims description 4
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 claims description 4
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims description 4
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 3
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 3
- 235000010323 ascorbic acid Nutrition 0.000 claims description 3
- 239000011668 ascorbic acid Substances 0.000 claims description 3
- 229960005070 ascorbic acid Drugs 0.000 claims description 3
- 239000008101 lactose Substances 0.000 claims description 3
- 229910052708 sodium Inorganic materials 0.000 claims description 3
- -1 sucrose fatty ester Chemical class 0.000 claims description 3
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims description 2
- CIWBSHSKHKDKBQ-DUZGATOHSA-N D-araboascorbic acid Natural products OC[C@@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-DUZGATOHSA-N 0.000 claims description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 2
- 235000019282 butylated hydroxyanisole Nutrition 0.000 claims description 2
- 235000010350 erythorbic acid Nutrition 0.000 claims description 2
- 239000008103 glucose Substances 0.000 claims description 2
- 239000000787 lecithin Substances 0.000 claims description 2
- 235000010445 lecithin Nutrition 0.000 claims description 2
- 229940067606 lecithin Drugs 0.000 claims description 2
- 150000008442 polyphenolic compounds Chemical class 0.000 claims description 2
- 235000013824 polyphenols Nutrition 0.000 claims description 2
- 235000010378 sodium ascorbate Nutrition 0.000 claims description 2
- PPASLZSBLFJQEF-RKJRWTFHSA-M sodium ascorbate Substances [Na+].OC[C@@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RKJRWTFHSA-M 0.000 claims description 2
- 229960005055 sodium ascorbate Drugs 0.000 claims description 2
- PPASLZSBLFJQEF-RXSVEWSESA-M sodium-L-ascorbate Chemical compound [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RXSVEWSESA-M 0.000 claims description 2
- DINKXUCRJBUQAZ-UHFFFAOYSA-N tert-butyl 5-bromopyridine-3-carboxylate Chemical compound CC(C)(C)OC(=O)C1=CN=CC(Br)=C1 DINKXUCRJBUQAZ-UHFFFAOYSA-N 0.000 claims description 2
- 239000011162 core material Substances 0.000 abstract description 9
- 238000000034 method Methods 0.000 abstract description 7
- 239000000843 powder Substances 0.000 abstract description 7
- 235000013365 dairy product Nutrition 0.000 abstract description 3
- 238000011031 large-scale manufacturing process Methods 0.000 abstract description 3
- 230000008569 process Effects 0.000 abstract description 3
- 238000001694 spray drying Methods 0.000 abstract description 3
- 235000013402 health food Nutrition 0.000 abstract description 2
- 239000003513 alkali Substances 0.000 abstract 1
- 235000013361 beverage Nutrition 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 239000000230 xanthan gum Substances 0.000 abstract 1
- 235000010493 xanthan gum Nutrition 0.000 abstract 1
- 229940082509 xanthan gum Drugs 0.000 abstract 1
- 235000019198 oils Nutrition 0.000 description 22
- 150000003904 phospholipids Chemical class 0.000 description 10
- 241000239366 Euphausiacea Species 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 230000036541 health Effects 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 238000011161 development Methods 0.000 description 3
- 230000018109 developmental process Effects 0.000 description 3
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 229940022405 astaxanthin Drugs 0.000 description 2
- 239000001168 astaxanthin Substances 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 230000002349 favourable effect Effects 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 235000001497 healthy food Nutrition 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- 208000024827 Alzheimer disease Diseases 0.000 description 1
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 description 1
- 206010008111 Cerebral haemorrhage Diseases 0.000 description 1
- 229920001661 Chitosan Polymers 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 201000005569 Gout Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 201000001429 Intracranial Thrombosis Diseases 0.000 description 1
- 206010039966 Senile dementia Diseases 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000001785 acacia senegal l. willd gum Substances 0.000 description 1
- 239000003463 adsorbent Substances 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000002929 anti-fatigue Effects 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 235000013793 astaxanthin Nutrition 0.000 description 1
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 description 1
- 238000000889 atomisation Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 150000007516 brønsted-lowry acids Chemical class 0.000 description 1
- 150000007528 brønsted-lowry bases Chemical class 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 235000021323 fish oil Nutrition 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 229940094952 green tea extract Drugs 0.000 description 1
- 235000020688 green tea extract Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 230000000324 neuroprotective effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000001525 retina Anatomy 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 235000013616 tea Nutrition 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
- A23D9/02—Other edible oils or fats, e.g. shortenings, cooking oils characterised by the production or working-up
- A23D9/04—Working-up
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicinal Preparation (AREA)
- General Preparation And Processing Of Foods (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to high-content krill oil microcapsules and a preparation technology thereof. The technology comprises the following steps: by taking krill oil and microporous starch as core materials, adding a small amount of xanthan gum into oil phase; and by taking chitosan oligosaccharide and oxidized starch as wall materials, mixing an oil-phase antioxidant, a water-phase antioxidant, an emulsifier, a dispersant and the like in proportion to prepare micro-emulsion, and performing spray drying to prepare krill oil microcapsule powder. The obtained krill oil microcapsule product contains 10-30 percent of phosphatide and keeps biological activity, improves the light-heat stability, acid-alkali stability and the like of krill oil, has good solubility in cold water, and is relatively easy to process, transport and store, safety, fluidity and water solubility are greatly improved, the application range of krill oil is enlarged, and the krill oil is an excellent health-food raw material, and is widely applied to dairy products, beverages, health-care products, baking, tablets and the like. The yield of the krill oil microcapsule powder prepared according to the technology is high, the phosphatide content of the product is high, and the technology is suitable for mass preparation of krill oil microcapsule powder and realizes continuous large-scale production.
Description
Technical field
The present invention relates to the production technical field of krill oil microcapsules, be specifically related to a kind of krill oil microcapsules and preparation technology thereof of high-load.
Background technology
Krill is one of biology the highest containing protein had been found that, protein content reaches more than 50 percent, but also containing the very abundant necessary amino acid of tissue and vitamin A, that the Nature is presented to the natural health food of the mankind, containing the irreplaceable effect of other food.
The phosphatide mating type Omega-3(that antarctic krill oil contains comprises EPA and DHA), easilier than the triglyceride type Omega-3 in fish oil absorbing, is effective source of DHA and EPA.In addition, krill oil is also containing natural---astaxanthin.Astaxanthin, except energy angiocardiopathy preventing, also has protective effect to retina and central nervous system.The health care of krill oil comprises: reduce blood fat, cholesterol, prevention cerebral hemorrhage, cerebral thrombus; Reduce blood viscosity, stimulate circulation, preventing hypertension; Brain tonic and intelligence development, active thinking, prevention senile dementia; Neuroprotective cell membrane, strengthens notice and memory, comprehension; Promote that Fetal Brain is grown; Antifatigue; Alleviate gout and rheumatoid arthritis; Reduce stiff, swelling and Tender Joint; Green Tea Extract, delaying aging; Obviously improve the wrinkle of skin degree of depth; Support vision health; Improve women's premenstrual molimen symptom etc.
In China, be still in the starting stage to the exploitation of krill resource, in China's patent protection; the patent of krill oil extraction aspect accounts for main body; and the patent of krill oil microcapsual powder or pulverulent product is less, and the krill oil content of phospholipid of microcapsule powder is lower, because which limit the range of application of krill oil.Because krill has become one of important content of national marine development strategy deposit, thus the technical research of krill development of resources is accelerated, prepare the krill oil microcapsule powder of high-load, expand the range of application of krill oil, realize producing the industrialization of krill resource, be significant.
Spray drying process is dispersed in by core material in the solution containing capsule material, mixes, drier by aerodynamic atomization, and solvent is evaporated rapidly, and wall material solidifies, and core material is coated on and wherein forms micro-capsule.
In the selection of microcapsule wall material, the application of conventional wall material is more as gelatin, casein sodium, Arabic gum etc., but the microcapsule product content often obtained is lower, is unsuitable for the preparation of high-load product.In addition, the product mobility of protide wall material, water-soluble relatively poor, be especially unfavorable for that cold water spreads, release property is poor, have impact on the result of use of product greatly.Therefore, prepare the krill oil microcapsules pulvis of high-load, select suitable microcapsule wall material to be the most key to microcapsules technology, it directly determines microencapsulation embedding effect, product content and release characteristics.
Summary of the invention
Technical problem to be solved by this invention is exactly for the deficiencies in the prior art, provides a kind of krill oil microcapsules and preparation technology thereof of high-load.This technique for core, and adds a small amount of xanthans at oil phase with krill oil, micropore starch; With chitosan oligosaccharide, oxidized starch for wall material, mix in proportion with oil phase antioxidant, aqueous phase antioxidant, emulsifying agent, dispersant etc., make microemulsion, more spray-driedly make krill oil microcapsules pulvis.The content of phospholipid of gained krill oil microcapsule product is 10-30%, maintain biologically active, improve krill oil to the stability of photo-thermal, soda acid etc., also there is good dissolubility in cold water, be more conducive to processing, transport and store, substantially increase the security of product, mobility and water-soluble, expanding the range of application of krill oil, is excellent healthy food material, is widely applied to dairy products, drink, health products, cures, tablet etc.Use this technique to prepare krill oil microcapsules pulvis productive rate high, in product, content of phospholipid is high, is suitable for preparing krill oil microcapsules pulvis in a large number, realizes serialization large-scale production.
The krill oil microcapsules of high-load and a preparation technology thereof, is characterized in that: described krill oil microcapsules are made up of core, wall material, oil phase antioxidant, aqueous phase antioxidant, emulsifying agent, dispersant,
Described wall material is chitosan oligosaccharide, oxidized starch and a small amount of xanthans;
Described core is krill oil, micropore starch;
Described dispersant is the one or any two or three in sucrose, glucose, trehalose, lactose;
Described oil phase antioxidant is the one or any two or three in natural VE, butylated hydroxy anisole (BHA), butyl hydroxy toluene (BHT), n-propyl gallate (PG), TBHQ (TBHQ);
Described aqueous phase antioxidant is the one or any two or three in Tea Polyphenols, ascorbic acid, EDTA-Na, sodium ascorbate, D-araboascorbic acid sodium;
Described emulsifying agent is the one or any two or three in monoglyceride, sucrose fatty ester, lecithin.
Preferably, the preparation technology of the krill oil microcapsules of a kind of high-load as above, is characterized in that, comprise the steps:
(1) oxidized starch of 10-60%, the chitosan oligosaccharide of 1-5% are joined 60 ~ 100 DEG C, stirring and dissolving in the water of 50-90%, the aqueous phase antioxidant of the dispersant of 0.1-6%, 0.1-6%, the emulsifying agent of 0.1-6% are joined in the solution dissolved, stirring makes it to mix, 50 ~ 70 DEG C of insulation stand for standby use, obtained aqueous phase;
(2) by the xanthans of the micropore starch of the krill oil of 10-80%, 1-10%, 0.1-0.25%, 0.1 ~ 1% the mixing of oil phase antioxidant, 60 ~ 90 DEG C of oil bath 3 ~ 10min, obtained oil phase;
(3) by the aqueous phase that dissolved and oil phase blowing simultaneously, control flow respectively, by aqueous phase: oil phase=5-1:1(mass ratio) use pipeline cutter on-line mixing, revolution 10000 ~ 16000 revs/min of 5 ~ 10min, 19000 ~ 28000 revs/min of 5 ~ 8min, and then homogeneous under 30 ~ 50Mpa, obtained microemulsion;
(4) microemulsion is carried out spraying dry, spray tower intake air temperature controls at 150 ~ 190 DEG C, and air outlet temperature controls at 60 ~ 90 DEG C, atomizer rotating speed 1000 ~ 1400r/min; Obtained krill oil microcapsules.
Advantageous Effects of the present invention is:
1, take chitosan oligosaccharide as wall material.In patent document both domestic and external, more using shitosan as wall material, application chitosan oligosaccharide is that wall material is little, but chitosan oligosaccharide is compared with shitosan, has more advantage.Chitosan oligosaccharide is the degree of polymerization after degradation of chitosan is the product of 2-10.Water insoluble and the aqueous slkali of shitosan, dissolves in most of low concentration inorganic acid or organic acid, therefore as wall material, usually must be dissolved in acetic acid and using, and chitosan oligosaccharide water soluble, bronsted lowry acids and bases bronsted lowry solution, apply more extensive.Chitosan oligosaccharide has better moisture absorption, moisturizing and film forming, the characteristic that there is good biocompatibility and easily absorb, its filming performance is the ideal material making krill oil microcapsules, reach the effect of slowly-releasing, controlled release core, keep krill oil biologically active, chitosan oligosaccharide molecular weight is little, and more than 99% can be absorbed, and can be widely used in food, medicine, cosmetics, agricultural and feedstuff industry.
2, adopt micropore starch as core and adsorbent in technical solution of the present invention, the function of sheltering can be played, prevent krill oil oxidized, with oxidized starch, xanthans with the use of, make the biologically active that product reaches the highest, improve shelf time.
3, in this technique, oil phase with the addition of a small amount of xanthans as wall material, and xanthans has unique strong anti-oxidation performance, is very favourable for oxidizable krill oil core.In addition, xanthans has larger viscosity, special cutting performance and high emulsibility can be conducive to the stable of emulsion, can strengthen the compactness of wall material and the oxidation resistance of product.Xanthans is very favourable for forming larger droplet in spray-drying process, can obtain larger particles and the mobility improving microscapsule powder.
4, krill oil microcapsule preparation process of the present invention, products obtained therefrom maintains biologically active, improve krill oil to the stability of photo-thermal, soda acid etc., also there is good dissolubility in cold water, be more conducive to processing, transport and store, substantially increase the security of product, mobility and water-soluble, expanding the range of application of krill oil, is excellent healthy food material, is widely applied to dairy products, drink, health products, cures, tablet etc.Use this technique to prepare krill oil microcapsules pulvis productive rate high, in product, content of phospholipid is high, is suitable for preparing krill oil microcapsules pulvis in a large number, realizes serialization large-scale production.
Detailed description of the invention
For the technical characterstic of the present invention program can be clearly demonstrated, below in conjunction with specific embodiment, the present invention is set forth.But protection scope of the present invention is not limited to these embodiments.Every do not deviate from the present invention's design change or equivalent substituting include within protection scope of the present invention.
embodiment 1
(1) oxidized starch of 35kg, 3kg chitosan oligosaccharide are joined stirring and dissolving in the 210kg water of 90 DEG C, 5kg trehalose, 5kg EDTA-Na, 0.1kg monoglyceride are joined in the solution dissolved, stirs and make it to mix, 50 ~ 70 DEG C of insulation stand for standby use, obtained aqueous phase;
(2) by 65kg krill oil (content of phospholipid is 40%), 5kg micropore starch, 0.2kg xanthans, 0.1kg natural VE, 0.1kg TBHQ (TBHQ) mixing, 90 DEG C of oil bath 3 ~ 10min, obtained oil phase.
(3) by the aqueous phase that dissolved and oil phase blowing simultaneously, control flow respectively, by aqueous phase: oil phase=4:1(mass ratio) use pipeline cutter on-line mixing, revolution 10000 ~ 16000 revs/min of 5 ~ 10min, 19000 ~ 28000 revs/min of 5 ~ 8min, and then homogeneous under 30 ~ 50Mpa, obtained microemulsion.
(4) microemulsion is carried out spraying dry, spray tower intake air temperature controls at 150 ~ 190 DEG C, and air outlet temperature controls at 60 ~ 90 DEG C, atomizer rotating speed 1000 ~ 1400r/min; Obtained krill oil microcapsules.In this microcapsule product, content of phospholipid is not less than 20%.
embodiment 2
(1) oxidized starch of 25kg, 2kg chitosan oligosaccharide are joined stirring and dissolving in the 210kg water of 90 DEG C, 5kg trehalose, 5kg EDTA-Na, 0.1kg monoglyceride are joined in the solution dissolved, stirs and make it to mix, 50 ~ 70 DEG C of insulation stand for standby use, obtained aqueous phase;
(2) by 80kg krill oil (content of phospholipid is 40%), 5kg micropore starch, 0.2kg xanthans, 0.1kg natural VE, 0.1kg TBHQ (TBHQ) mixing, 90 DEG C of oil bath 3 ~ 10min, obtained oil phase.
(3) by the aqueous phase that dissolved and oil phase blowing simultaneously, control flow respectively, by aqueous phase: oil phase=3:1(mass ratio) use pipeline cutter on-line mixing, revolution 10000 ~ 16000 revs/min of 5 ~ 10min, 19000 ~ 28000 revs/min of 5 ~ 8min, and then homogeneous under 30 ~ 50Mpa, obtained microemulsion.
(4) microemulsion is carried out spraying dry, spray tower intake air temperature controls at 150 ~ 190 DEG C, and air outlet temperature controls at 60 ~ 90 DEG C, atomizer rotating speed 1000 ~ 1400r/min; Obtained krill oil microcapsules.In this microcapsule product, content of phospholipid is not less than 25%.
embodiment 3
(1) oxidized starch of 20kg, 1kg chitosan oligosaccharide are joined stirring and dissolving in the 420kg water of 90 DEG C, by 5kg lactose, 5kg ascorbic acid, 0.2kg sucrose ester joins in the solution dissolved, and stirs and makes it to mix, 50 ~ 70 DEG C of insulation stand for standby use, obtained aqueous phase;
(2) by 150kg krill oil (content of phospholipid is 40%), 10kg micropore starch, 0.4kg xanthans, 0.2kg natural VE, 0.2kg n-propyl gallate (PG) mixing, 90 DEG C of oil bath 3 ~ 10min, obtained oil phase.
(3) by the aqueous phase that dissolved and oil phase blowing simultaneously, control flow respectively, by aqueous phase: oil phase=3:1(mass ratio) use pipeline cutter on-line mixing, revolution 10000 ~ 16000 revs/min of 5 ~ 10min, 19000 ~ 28000 revs/min of 5 ~ 8min, and then homogeneous under 30 ~ 50Mpa, obtained microemulsion.
(4) microemulsion is carried out spraying dry, spray tower intake air temperature controls at 150 ~ 190 DEG C, and air outlet temperature controls at 60 ~ 90 DEG C, atomizer rotating speed 1000 ~ 1400r/min; Obtained krill oil microcapsules.In this microcapsule product, content of phospholipid is not less than 30%.
Claims (2)
1. the krill oil microcapsules of high-load and a preparation technology thereof, is characterized in that: described krill oil microcapsules are made up of core, wall material, oil phase antioxidant, aqueous phase antioxidant, emulsifying agent, dispersant;
Described wall material is chitosan oligosaccharide, oxidized starch and a small amount of xanthans;
Described core is krill oil, micropore starch;
Described dispersant is the one or any two or three in sucrose, glucose, trehalose, lactose;
Described oil phase antioxidant is the one or any two or three in natural VE, butylated hydroxy anisole (BHA), butyl hydroxy toluene (BHT), n-propyl gallate (PG), TBHQ (TBHQ);
Described aqueous phase antioxidant is the one or any two or three in Tea Polyphenols, ascorbic acid, EDTA-Na, sodium ascorbate, D-araboascorbic acid sodium;
Described emulsifying agent is the one or any two or three in monoglyceride, sucrose fatty ester, lecithin.
2. the krill oil microcapsules of a kind of high-load according to claim 1 and preparation technology thereof, is characterized in that, comprise the steps:
(1) oxidized starch of 10-60%, the chitosan oligosaccharide of 1-5% are joined 60 ~ 100 DEG C, stirring and dissolving in the water of 50-90%, the aqueous phase antioxidant of the dispersant of 0.1-6%, 0.1-6%, the emulsifying agent of 0.1-6% are joined in the solution dissolved, stirring makes it to mix, 50 ~ 70 DEG C of insulation stand for standby use, obtained aqueous phase;
(2) by the xanthans of the micropore starch of the krill oil of 10-80%, 1-10%, 0.1-0.25%, 0.1 ~ 1% the mixing of oil phase antioxidant, 60 ~ 90 DEG C of oil bath 3 ~ 10min, obtained oil phase;
(3) by the aqueous phase that dissolved and oil phase blowing simultaneously, control flow respectively, by aqueous phase: oil phase=5-1:1(mass ratio) use pipeline cutter on-line mixing, revolution 10000 ~ 16000 revs/min of 5 ~ 10min, 19000 ~ 28000 revs/min of 5 ~ 8min, and then homogeneous under 30 ~ 50Mpa, obtained microemulsion;
(4) microemulsion is carried out spraying dry, spray tower intake air temperature controls at 150 ~ 190 DEG C, and air outlet temperature controls at 60 ~ 90 DEG C, atomizer rotating speed 1000 ~ 1400r/min; Obtained krill oil microcapsules.
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