CN104792740B - Spiral lift biological marker analyte detection light spectral position regulating device - Google Patents

Spiral lift biological marker analyte detection light spectral position regulating device Download PDF

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Publication number
CN104792740B
CN104792740B CN201510132895.9A CN201510132895A CN104792740B CN 104792740 B CN104792740 B CN 104792740B CN 201510132895 A CN201510132895 A CN 201510132895A CN 104792740 B CN104792740 B CN 104792740B
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China
Prior art keywords
batten
coil
threaded rod
fixed
magnet
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Expired - Fee Related
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CN201510132895.9A
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Chinese (zh)
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CN104792740A (en
Inventor
张贯京
陈兴明
葛新科
克里斯基捏·普拉纽克
艾琳娜·古列莎
王海荣
张少鹏
方静芳
高伟明
程金兢
梁艳妮
周荣
李慧玲
邢立立
波达别特·伊万
徐之艳
周亮
梁昊原
肖应芬
郑慧华
唐小浪
李潇云
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SHENZHEN SHENGBIZHI TECHNOLOGY DEVELOPMENT CO., LTD.
Original Assignee
Shenzhen Shengbizhi Technology Development Co Ltd
Shenzhen Beiwo Deke Biotechnology Research Institute Co Ltd
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Application filed by Shenzhen Shengbizhi Technology Development Co Ltd, Shenzhen Beiwo Deke Biotechnology Research Institute Co Ltd filed Critical Shenzhen Shengbizhi Technology Development Co Ltd
Priority to CN201510132895.9A priority Critical patent/CN104792740B/en
Priority to PCT/CN2015/078020 priority patent/WO2016149990A1/en
Publication of CN104792740A publication Critical patent/CN104792740A/en
Application granted granted Critical
Publication of CN104792740B publication Critical patent/CN104792740B/en
Expired - Fee Related legal-status Critical Current
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • G01N21/552Attenuated total reflection

Abstract

Spiral lift biological marker analyte detection light spectral position regulating device, the present invention relates to biomarker detection fields, more specifically to it is used for the auxiliary device of biological marker analyte detection, including batten (2), mirror (3), threaded rod (7), pedestal (8), coil (9) and magnet (10), mirror (3) setting is at one end on hinged fixed batten (2), threaded hole (6) are offered on batten (2), threaded rod (7) one end is rotatable to be fixed on pedestal (8), the other end is screwed in threaded hole (6), coil (9) is fixed on threaded rod (7), magnet (10) is close to the coil (9), enable its rotary motion under the action of magnet (10) after being powered into coil (9), the present invention can facilitate, efficiently change biomarker In surface plasma resonance technology checking process in detectable substance the infrared radiation reflection light of biomarker spectral position, to obtain the effective information of biomarker in detectable substance.

Description

Spiral lift biological marker analyte detection light spectral position regulating device
Technical field
The present invention relates to biomarker detection field, more specifically to biological marker analyte detection uses up spectrum dark space position Set regulating device.
Background technique
Biomarker (Biomarker) refers to can be with tagging system, organ, tissue, cell and subcellular structure or function The biochemical indicator of change or the change that may occur of energy, has very extensive purposes.Biomarker can be used for disease and examine Break, judge staging or for evaluating the safety and efficacy of new drug or new treatment in target group.It is given birth in detection When object marker, surface plasma resonance technology SPR (Surface Plasmon Resonance) is commonly used, that is, utilizes metal The total reflection of film/liquid level interface light connects a kind of caused physical optics phenomenon to analyze bio-molecular interaction, and passes through Infrared light combination SPR technique measures biomarker concentration, and specifically can refer to paper, " surface plasma resonance technology is cured in biology Application in " -2004 grades of Peking University's biomedical engineering Zhang Rui Bin (10403048) and paper " surface plasma Application and its progress of the resonance immunosensor in protein detection "-" analytical chemistry " the 7th phase 1052- in 2010 1059, however, how can more accurately obtain the characteristic spectrum of the infrared light of detection biomarker in measurement process Location information is pendulum in face of numerous field of biomedicine scholars to obtain the relevant information of biomarker in determinand A difficult problem.
Summary of the invention
In order to solve the above technical problem, the present invention provides one kind can obtain the reflection light of biomarker, and adjusts The spiral lift biological marker analyte detection of whole biomarker reflected light spectral position light spectral position regulating device.
The present invention to solve above-mentioned technical problem used by technical solution are as follows: spiral lift biological marker analyte detection use Spectral position regulating device, including mirror, batten, threaded rod, pedestal, coil and magnet, the mirror setting is at one end On hinged fixed batten, threaded hole is offered on the batten, described threaded rod one end is rotatable to be fixed on institute On the pedestal stated, the other end is screwed in threaded hole, and the coil is fixed on the threaded rod, and the magnet is close The coil, enable into the coil be powered after its rotary motion under the action of the magnet.
For the light spectral position regulating device of the spiral lift biological marker analyte detection in the present invention, as further It limits, the coil extends the screw thread bar body.
For spiral lift biological marker analyte detection above-mentioned in present invention light spectral position regulating device, as into one The setting of step, is additionally provided with balancing device on the threaded rod, and the balancing device and the coil are distributed in described The two sides of threaded rod.
For spiral lift biological marker analyte detection above-mentioned in present invention light spectral position regulating device, as being directed to The further setting of balancing device, the balancing device are the annulus of closure.
For spiral lift biological marker analyte detection above-mentioned in present invention light spectral position regulating device, as being directed to The further setting of batten limits, and the batten includes tilting section and horizontal segment, and the mirror is fixed on the inclination Duan Shang, the threaded hole are provided on the horizontal segment of the batten.
For the light spectral position regulating device of the spiral lift biological marker analyte detection in the present invention, as mirror Position is arranged on batten to further limit, the mirror setting is on the tilting section of the batten, and along the inclination The extending direction distribution of section.
For spiral lift biological marker analyte detection above-mentioned in present invention light spectral position regulating device, as into one The setting of step further includes spring, and the spring one end is fixed, and the other end is fixedly connected with the batten, the batten By the spring supporting.
For spiral lift biological marker analyte detection above-mentioned in present invention light spectral position regulating device, as being directed to A kind of optinal plan of position is arranged in spring, and the spring one end is fixed, and the other end is connect with the horizontal segment of the batten.
For spiral lift biological marker analyte detection above-mentioned in present invention light spectral position regulating device, as being directed to A kind of optinal plan of position is arranged in spring, and the spring one end is fixed, and the hinged fixing end of the other end and the batten connects It connects.
For spiral lift biological marker analyte detection above-mentioned in present invention light spectral position regulating device, as being directed to The optimal selection of magnet, the magnet are neodium magnet.
In the present invention, a bearing can be fixed on pedestal, and be fixed on the base the outer ring of bearing, then by screw thread Bar is fixed on the inner ring of bearing, so that threaded rod can be moved in lower resistance around its own center axis rotation.Meanwhile it being asked for this Topic, also can be used existing other way, will not enumerate herein.
In the present invention, combination is screwed for threaded rod and batten upper screwed hole, similar engagement can also be selected Mode is replaced, such as: threaded rod is changed to worm gear, coil is fixed on worm gear, the thread pore structure on batten is replaced It is changed to worm screw or worm structure, is transmitted by the engagement of worm and gear, realizes the adjusting to batten, completion is to batten and its above Mirror adjusting;Threaded rod can also be replaced with to gear, coil is fixed on gear accordingly, by the threaded hole on batten Structure changes rack gear or similar rack structure into, so that coil is rotated under the action of magnet by band moving gear, and then with movable tooth Item and batten are moved, the position of mirror so as to adjust batten and its above or/and angle.
Spiral lift biological marker analyte detection of the present invention by adopting the above technical scheme, is brought with light spectral position regulating device Technical effect are as follows: hingedly fixed, and passed through since present invention employs the battens for being fixed with mirror, and by batten one end Spring supporting is provided with threaded hole on batten, and is screwed in the rotatable fixed threaded rod in one end in threaded hole, Fixed coil is nearby equipped with magnet on threaded rod, (or changes being passed through electric current into coil and is passed through the big of electric current in coil Small and direction) when, due to the magnetic field interaction that electromagnetic induction principle, coil generation magnetic field, the magnetic field and magnet generate, herein Effect lower coil drive threaded rod start rotary motion, the threaded hole on batten with threaded rod rotation so that batten with Associated movement, the angle of mirror can also change therewith on batten, to change incidence/outgoing in infrared radiation to mirror Angle controls the position that related infrared light is formed by dark space on spectrum acquisition device, obtains the biology mark in detectable substance The relevant information of will object, the adjustment process is very succinct reliable, and is very easy to operation, and high sensitivity can be easily and efficiently Change the infrared radiation reflected light of biomarker in detectable substance in biomarker surface plasma resonance technology checking process The spectral position information of line, to obtain the effective information of biomarker in detectable substance.
Detailed description of the invention
Fig. 1 is that the overall structure of spiral lift biological marker analyte detection light spectral position regulating device of the present invention is illustrated Figure;
Fig. 2 is that the overall structure of spiral lift biological marker analyte detection light spectral position regulating device of the present invention overlooks shape State schematic diagram;
Fig. 3 is spiral lift biological marker analyte detection light spectral position regulating device of the present invention about spring setting position The structural schematic diagram for another embodiment set;
Fig. 4 is that the use state of spiral lift biological marker analyte detection light spectral position regulating device of the present invention is illustrated Figure.
Specific embodiment
In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below in conjunction with the embodiment of the present invention In attached drawing, technical solution in the embodiment of the present invention is explicitly described, it is clear that described embodiment is the present invention A part of the embodiment, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not having Every other embodiment obtained under the premise of creative work is made, shall fall within the protection scope of the present invention.
Fig. 1 is overall structure diagram of the invention, as shown, spiral lift biological marker analyte detection uses up spectrum position Regulating device, including batten 2, spring 4, threaded rod 7, pedestal 8, coil 9 and magnet 10 are set, one end of batten 2 is with hinged side Formula is fixed, and the other end is equipped with threaded hole 6, and a threaded rod 7 is equipped in threaded hole 6, and threaded rod 7 is screwed in threaded hole 6, Threaded rod 7 is rotatably fixed on pedestal 8, for ease of use, can set batten 2 to the two parts being fixedly connected, and one Part is tilting section 21, and another part is horizontal segment 22, and one end of tilting section 21 fixes using hinged by the way of, the other end and Horizontal segment 22 is fixedly connected, and tilting section 21 and horizontal direction is made to be a certain included angle (in the majority with acute angle under normal circumstances), It is fixedly installed mirror 3 on tilting section 21, for reflecting infrared light when detection biomarker, is offered on horizontal segment In comparison threaded hole 6, opens up it is of course also possible in addition fix a nut on the horizontal segment 22 on horizontal segment 22 Threaded hole 6, that is, the structure for being made of one formula can be more convenient in production, installation and use.
In Fig. 1, threaded hole 6 and threaded rod 7 on batten 2 are in the state being screwed together, i.e., batten 2 is with threaded hole 6 are screwed on threaded rod 7, and the state in a vertical shape of threaded rod 7, when threaded rod 7 rotates under the effect of external force, batten 2 is with it Threaded hole 6 above moves up and down together along threaded rod 7, due to 2 one end of batten be it is hinged fixed, in threaded rod Under 7 induced effect, batten 2 can be moved in a circle centered on its fixing end (for supporting point 1 in figure) accordingly.In order to control The rotation of system/adjusting threaded rod 7, so that the movement of batten 2 and its mirror 3 above is controlled/adjusts, it is fixed on threaded rod 7 One closure coil 9, which will extend the ontology of threaded rod 7, and a distance that extends outwardly, with 9 bottom of coil One fixed magnet 10 is set, projection of a part of coil 9 with magnet 10 in same orientation is Chong Die, in this way since, when When being passed through electric current on coil 9, the coil 9 in closed state forms the circuit of a closure, when in the circuit of this closure When having electric current to pass through, its own generates magnetic field under electromagnetic induction effect, and the magnetic field that coil 9 generates and the magnetic field of magnet 10 are mutual Between have an effect power, at this point, changing the size of current/direction being passed through in coil 9, to can change magnetic field caused by coil 9 strong Degree and magnetic direction, the size and Orientation in the magnetic field as caused by magnet 10 be it is fixed, when change coil 9 in Size of current and/or when direction, under the action of the magnetic field of magnet 10, coil 9 rotates, since coil 9 is to be fixed on On threaded rod 7, therefore, when coil 9 starts turning, threaded rod 7 can be rotated with the rotation of coil 9, and threaded rod 7 screws In 2 upper screwed hole 6 of batten, therefore batten 2 will be also moved with the rotation of threaded rod 7 (for above and below vertical direction in figure Movement), final batten 2 can also be moved with the variation of electric current in coil 9, for batten 2, since its tilting section 21 is to cut with scissors The mode connect is fixed, therefore, when batten 2 is with being passed through the variation of electric current in coil 9 and changing, the tilting section of batten 2 21 will also change therewith with the angle of horizontal direction, in turn, be fixed on the angle of the mirror 3 and horizontal direction on batten 2 Just with change, the angle of reflection light above can also change therewith.
In the present invention, for fixed form of the threaded rod 7 on pedestal 8, can be selected existing any makes threaded rod 7 can The method of rotation being fixed on the base, for example, threaded rod 7 is fixed on axis using a bearing is fixedly installed on pedestal 8 On the inner ring held, so that threaded rod 7 under external force can be with the inner ring rotary motion of bearing;Locating slot and card can also be used The mode of the mode that slot combines, the rotary fixing structure as disclosed in patent CN99246418.8 consolidates threaded rod 7 It is fixed.Other enforceable set-up modes will not enumerate herein.
As shown in Figure 1, in order to further increase the adjusting sensitivity of the horizontal sextant angle of the mirror 3 on batten 2, in batten 2 One spring 4 of upper connection, the other end of spring 4 are fixed, and an initial position are set, so that spring 4 is whole in the initial position A device is in a zero point, can be by the elastic force of spring 4, so that mirror 3 is more when needing to adjust the horizontal sextant angle of mirror 3 Add and is easy to return back to initial position.Above-mentioned detailed process is showed themselves in that when being passed through electric current into coil 9, generates magnetic field in coil, Under the action of magnet 10, coil 9 drives 7 common rotation of threaded rod in the active force of magnetic field interaction, and threaded rod 7 starts turning, item Plate 2 is as rise/fall, i.e. batten 2 rising overally/decline the threaded hole 6 above it occur under the rotation of threaded rod 7 Gesture, batten 2 start, when batten 2 starts rotary motion, also to start to draw simultaneously using its hinged fixed point as axle center rotary motion / compressed spring 4 is stretched, when batten 2 and its mirror 3 above need to be made to return back to the position of initial position or required setting, works as phase The change answered is passed through size of current or/and direction in coil 9, and batten 2 when moving accordingly with threaded rod 7, spring 4 Convergent force or drawing force can be provided accordingly, enable batten 2 sensitiveer, fast under the assistance of the active force of spring 4 Speed returns back to initial position or required position.
Fig. 2 is that the overall structure of spiral lift biological marker analyte detection light spectral position regulating device of the present invention overlooks shape State schematic diagram, as shown in Fig. 2, mirror 3 extends distribution, screw thread along the length direction of the tilting section 21 of batten 2 under overlooking state Hole 6 is located on the horizontal segment 22 of batten 2, and batten 2 is screwed on threaded rod 7 with threaded hole 6, the central axis and threaded rod 7 of coil 9 Extending direction it is identical, meanwhile, magnet 10 is located at the lower section of coil 9, it is noted that so that coil 9 be located at magnet 10 magnetic field it In, so that coil 9 is in the magnetic field that its own is generated and magnet after being passed through electric current in coil 9 or changing the size of electric current being passed through 10 generate magnetic fields interaction under, by magnet 10 active force and move, the orientation of Cong Tuzhong is seen, coil 9 is in magnet 10 Under the action of, it can be the rotation of center axis with threaded rod 7, and drive 7 common rotation of threaded rod.
For the setting position of 4 position of spring, a kind of embodiment can refer to Fig. 1 and Fig. 2, will one end of which is fixed on battens On 2 horizontal segment 22, the other end is fixed on corresponding position (such as in platform or rack etc.), in such cases, spring 4 and branch Support point 1 is intended to support from two ends of batten 2, and in this case, there is support at the both ends of batten 2, relatively For, the position of batten 2 is comparatively stable, but due to the supporting role of spring 4, batten 2 is generally in a kind of more sensitive Adjustable state, i.e., towards batten not hingedly fixed one end applied force when, batten 2 can under the action of the power applied, It is moved in a circle centered on supporting point 1, also, under the supporting role of spring 4, borrows the elasticity of spring 4, the fortune of batten 2 It is dynamic can be sensitiveer, it is easier to control and adjust.
Fig. 3 is spiral lift biological marker analyte detection light spectral position regulating device of the present invention about spring setting position The structural schematic diagram for another embodiment set, as shown, spring 4 is located at the hinged fixed one end of batten 2, such situation Under, spring 4 and supporting point 1 are intended to support and fix in one end of batten 2, in this way since, batten 2 is whole to be propped up Under the collective effect of 4 the two of support point 1 and spring, the structure for being similar to lever is formed, it at this moment, only need to be in batten 2 far from branch The end of support point 1 applies a lesser active force can change the initial position of batten 2 by leverage, that is, work as change When the electric current being passed through in coil 9, coil 9 rotates under the action of magnet 10, and threaded rod 7 is driven to rotate, due on batten 2 Threaded hole 6 is screwed on threaded rod 7, therefore batten 2 can rise equipped with one end of threaded hole with the rotation of threaded rod 7 Or decline, it can be fixed with supporting point 1 for axle center rotary motion (with vertical direction formula shown in figure) so that batten 2 is whole Mirror 3 on batten 2 is also with common pivoting movement, to play the purpose for adjusting 3 angle with horizontal plane of mirror.
In the present invention, one end of batten 2 is hinged fixed, is can be used including hinge, hinged ball etc. herein A variety of articulated mountings and hinged fixed form, i.e., need to only ensure batten 2 can around supporting point 1 with lower frictional force rotation i.e. It can.
As shown in figs. 1-3, for the shape of magnet 10 is in scheme, (this direction is intuitive side in figure in the horizontal direction To specific setting orientation in kind is not limited thereto) setting magnet 10, referring in particular to the position of magnet 10 in Fig. 2, and make it The pole N and its pole S reasonable layout, enable coil 9 in the sphere of action in 10 magnetic field of magnet, the pole N of magnet 10 and the pole S it Between move, for magnet 10, in order to which sufficiently strong magnetic field can be generated, it is preferred to use neodium magnet can obtain stronger Magnetic field, can strength promote be powered after coil 9 movement;Its shape is not limited to strip shown in figure, It can also be common U magnet, bar magnet and slab-shaped magnet or uncommon but can be realized said function Magnet.
Further, as shown in figs. 1-3, it in order to improve stability of the coil 9 on threaded rod 7, and further mentions The adjusting sensitivity of high coil 9 fixes a balancing device 5 on threaded rod 7, which is mounted on threaded rod 7, Its position is corresponding with coil 9, i.e., so that balancing device 5 and coil 9 are located at the two sides of gear, and it is same to be located at the two One level height plays certain balanced action each other, here, balancing device 5 can be arranged to coiled type, can make Threaded rod 7 is extended in its part, can so mitigate the weight of balancing device 5, meanwhile, balancing device 5 can also be by Self gravity plays good balanced action to the position height of coil 9 under leverage, i.e., when coil 9 is by magnet 10 Magnetic field force (rotates in Fig. 1 using the fixed point of threaded rod 7 as fulcrum, for the fixed point of threaded rod 7 in Fig. 2 in the horizontal direction Movement is rotated in a vertical plane for fulcrum, it is identical with Fig. 1 in Fig. 3, orientation in figure is referred to only with upper position, actual direction is not Be limited to this) movement when, under the action of balancing device 5,9 need of coil overcome the power of very little that can get rid of stationary state to be transported It is dynamic, likewise, only lesser resistance need to be overcome to can be realized, i.e., without significantly when that need to adjust coil 9 to initial position The position adjustment to coil 9 can be realized in the electric current that variation is passed through in coil 9.
For the pedestal 8 in Fig. 1-Fig. 3, the common pedestal for assembling other components can be used, upper lower leaf can be used The structure of formula, and rotate its upper layer can in lower layer, at this moment threaded rod 7 need to be only directly anchored to the superstructure of pedestal 8 It is upper, in addition, also pedestal 8 can be arranged to adjustable height, in order to determine the initial position of adjustment whole device.
Fig. 4 is that the use state of spiral lift biological marker analyte detection light spectral position regulating device of the present invention is illustrated Figure, as shown in the figure, in the use of the present invention, can be first using the detection liquid without biomarker, using infrared light to inspection It surveys device to be irradiated, and is irradiated to its reflected light on mirror 3 by direction shown in Fig. 2, after the reflection of mirror 3, enter To spectrum acquisition device 12, the infrared ray after the reflection of mirror 3 is received by spectrum acquisition device 12, and determine spectrum dark space Position, in such cases, spiral lift biological marker analyte detection of the present invention are set as initial bit with light spectral position regulating device It sets, correspondingly, the dark space being formed by band-like smooth area and band-like smooth area at the spectrum acquisition device 12 under the state is also corresponding Be used as initial position, when changing measured detectable substance, due to presence/concentration variation of biomarker in detectable substance, Antibody in detection device absorbs antigen, and the reflected light for detecting the infrared light of irradiation changes, that is, is irradiated to mirror of the present invention Infrared light on son 3 changes, and then after its reflection, and infrared light received by spectrum acquisition device 12, which is sent, to be become Change, the spectrum formed on spectrum acquisition device 12 also sends variation therewith, and the position for being formed by dark space also will phase It shifts to initial position.
It take incident ray therein as the infrared external reflection light of detectable substance detected, using its emergent light as light referring to Fig. 4 The light for composing 12 actual received of reception device, when need to be adjusted to the dark space position of the spectrum formed on spectrum acquisition device 12 It is whole, when further relating to the details of biomarker to obtain, change size of current or/and the direction being passed through in coil 9, The intensity in magnetic field caused by the coil 9 being closed or/and direction change also with sending, in this way since, in the work of magnet 10 Under, coil 9 drives the rotation of threaded rod 7 (to be easier in the balancing brake effect lower coil 9 of balancing device 5 in magnet 10 Moved under magneticaction), and then threaded rod 7 drives batten 2 to move by the threaded hole 6 on batten 2, i.e., batten 2 also starts to transport Dynamic, the angle of mirror 3 and horizontal direction changes with the movement of batten 2, so that being irradiated to the incidence on mirror 3 The incidence angle of light changes, correspondingly, the angle of emergence also changes, emergent light is irradiated to the angle on spectrum acquisition device 12 Also it changes, therefore the position for the dark space that the infrared ray of object reflection is formed on spectrum acquisition device 12 after testing can also be sent out It is raw to change, i.e., the size of electric current or/and direction in coil 9 are passed through according to adjustment, it is corresponding to control shape on spectrum acquisition device 12 At dark space position, measurement needed for being obtained by the change of the dark space position and the change for the electric current being passed through in coil 9 Information.
It should be strongly noted that implementation of the invention is not limited to above-mentioned embodiment, for example, wherein realizing item The threaded rod 7 and screw batten 2 above it that plate 2 moves, by intermeshing turbine, worm screw or can also can be socketed Nut, the screw rod of installation carry out whole replacement, and the corresponding position as needed by required change is modified, for this Field technical staff and other field personnel of the existing machinery field common knowledge of combination very can readily make State variation;Moreover, the position of spring 4 is also not limited to position shown in figure in the present invention, other conjunctions can be also moved Right position is set, and is subject to easy to use.
Above in conjunction with attached drawing, the embodiment of the present invention is explained in detail, but the present invention is not limited to above-mentioned Embodiment within the knowledge of those skilled in the art can also be without departing from the purpose of the present invention Various changes can be made.

Claims (7)

1. spiral lift biological marker analyte detection light spectral position regulating device, it is characterised in that: including batten (2), mirror (3), threaded rod (7), pedestal (8), coil (9) and magnet (10), the mirror (3) setting are hinged fixed at one end It on batten (2), is offered on the batten (2) threaded hole (6), the batten (2) includes tilting section (21) and horizontal segment (22), the mirror (3) is fixed on the tilting section (21), and the threaded hole (6) is provided with the batten (2) On horizontal segment (22), the threaded rod (7) one end is rotatable to be fixed on the pedestal (8), and the other end is screwed in spiral shell In pit (6), the coil (9) is fixed on the threaded rod (7), and the coil (9) extends the screw thread Bar (7) ontology is additionally provided with balancing device (5) on the threaded rod (7), the balancing device (5) and the coil (9) two sides of the threaded rod (7) are distributed in, the magnet (10) is close to the coil (9), so as to the coil (9) It being capable of the rotary motion under the action of magnet (10) after middle energization.
2. spiral lift biological marker analyte detection according to claim 1 light spectral position regulating device, feature exist In: the balancing device (5) is the annulus of closure.
3. spiral lift biological marker analyte detection according to claim 2 light spectral position regulating device, feature exist In: the mirror (3) is arranged on the tilting section (21) of the batten (2), and the extending direction along the tilting section (21) Distribution.
4. spiral lift biological marker analyte detection according to claim 3 light spectral position regulating device, feature exist In: it further include spring (4), the spring (4) one end is fixed, and the other end is fixedly connected with the batten (2), the item Plate (2) is supported by the spring (4).
5. spiral lift biological marker analyte detection according to claim 4 light spectral position regulating device, feature exist In: described spring (4) one end is fixed, and the other end is connect with the horizontal segment (22) of the batten (2).
6. spiral lift biological marker analyte detection according to claim 4 light spectral position regulating device, feature exist In: described spring (4) one end is fixed, and the other end is close to supporting point (1) and is fixed on batten (2).
7. spiral lift biological marker analyte detection according to claim 1 light spectral position regulating device, feature exist In: the magnet (10) is neodium magnet.
CN201510132895.9A 2015-03-25 2015-03-25 Spiral lift biological marker analyte detection light spectral position regulating device Expired - Fee Related CN104792740B (en)

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CN201510132895.9A CN104792740B (en) 2015-03-25 2015-03-25 Spiral lift biological marker analyte detection light spectral position regulating device
PCT/CN2015/078020 WO2016149990A1 (en) 2015-03-25 2015-04-30 Spirally lifted/lowered spectral position adjusting apparatus for biomarker testing

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CN104792740B true CN104792740B (en) 2019-07-23

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