Summary of the invention
In order to solve the problems of the technologies described above, the invention provides a kind of reflection ray that can obtain biomarker, and adjust the spiral lift biomarker detection spectral position regulating device of biomarker reflected light spectral position.
The present invention for solving the problems of the technologies described above adopted technical scheme is: spiral lift biomarker detection spectral position regulating device, comprise mirror, batten, threaded rod, base, coil and magnet, described mirror is arranged on the hinged batten be fixed wtih in one end, described batten offers threaded hole, described threaded rod one end is rotatable to be fixed on described base, the other end is screwed in threaded hole, described coil is fixed on described threaded rod, described magnet is near described coil, after making in described coil energising, it can rotary motion under the effect of described magnet.
For the spiral lift biomarker detection spectral position regulating device in the present invention, as further restriction, described coil extends described threaded rod body.
For spiral lift biomarker detection spectral position regulating device above-mentioned in the present invention, as further setting, described threaded rod is also provided with balance device, described balance device and described coil are distributed in the both sides of described threaded rod.
For spiral lift biomarker detection spectral position regulating device above-mentioned in the present invention, as the further setting for balance device, described balance device is closed annulus.
For spiral lift biomarker detection spectral position regulating device above-mentioned in the present invention, as arranging restriction further for batten, described batten comprises tilting section and horizontal segment, described mirror is fixed on described tilting section, and described threaded hole is opened on the horizontal segment of described batten.
For the spiral lift biomarker detection spectral position regulating device in the present invention, as the further restriction for mirror setting position on batten, described mirror is arranged on the tilting section of described batten, and distributes along the bearing of trend of described tilting section.
For spiral lift biomarker detection spectral position regulating device above-mentioned in the present invention, as further setting, also comprise spring, described spring one end is fixed, the other end is fixedly connected with described batten, and described batten is by described spring supporting.
For spiral lift biomarker detection spectral position regulating device above-mentioned in the present invention, as a kind of possibility for spring setting position, described spring one end is fixed, and the other end is connected with the horizontal segment of described batten.
For spiral lift biomarker detection spectral position regulating device above-mentioned in the present invention, as a kind of possibility for spring setting position, described spring one end is fixed, and the other end is connected with the hinged stiff end of described batten.
For spiral lift biomarker detection spectral position regulating device above-mentioned in the present invention, as the optimal selection for magnet, described magnet is neodium magnet.
In the present invention, a bearing can be fixed on base, and make the outer ring of bearing be fixed on base, then threaded rod is fixed on the inner ring of bearing, make threaded rod can in lower resistance around himself central shaft rotary motion.Meanwhile, for this problem, also can adopt existing alternate manner, will not enumerate at this.
In the present invention, combination is screwed for threaded rod and batten upper screwed hole, similar engagement system can also be selected to replace, such as: threaded rod is changed to worm gear, coil is fixed on worm gear, the thread pore structure on batten is replaced with worm screw or worm structure, rely on the engagement transmission of worm and gear, realize the adjustment to batten, complete the adjustment to batten and mirror above thereof; Also threaded rod can be replaced with gear, accordingly coil is fixed on gear, thread pore structure on batten is changed into tooth bar or similar rack structure, coil is rotated by driven gear under the effect of magnet, and then be with carry-over bar and batten to move, thus the position of adjustment batten and mirror above thereof is or/and angle.
Spiral lift biomarker detection spectral position regulating device of the present invention adopts technique scheme, the technique effect brought is: owing to present invention employs the batten being fixed with mirror, and batten one end is carried out hinged fixing, and pass through spring supporting, batten is provided with threaded hole, and make the rotatable threaded rod be fixed wtih in one end be screwed in threaded hole, threaded rod near the coil be fixed wtih be provided with magnet, when passing into electric current (or changing the size and Orientation passing into electric current in coil) in coil, due to electromagnetic induction principle, coil produces magnetic field, the magnetic field interaction that this magnetic field and magnet produce, threaded rod is driven to start rotary motion in this effect lower coil, threaded hole on batten is along with the rotation of threaded rod, make batten along with associated movement, on batten, the angle of mirror also can change thereupon, thus change infrared radiation to the incidence/shooting angle on mirror, control the position of the dark space that relevant Infrared is formed on spectrum acquisition device, obtain the relevant information of the biomarker detected in thing, this adjustment process is very succinct reliable, and be very easy to operation, highly sensitive, can facilitate, change the spectral position information detecting the infrared radiation reflection ray of biomarker in thing in biomarker surface plasma resonance technology checking process efficiently, thus obtain the effective information detecting biomarker in thing.
Embodiment
For making the object of the embodiment of the present invention, technical scheme and advantage clearly, below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly described, obviously, described embodiment is the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Fig. 1 is one-piece construction schematic diagram of the present invention, as shown in the figure, spiral lift biomarker detects and uses spectral position regulating device, comprise batten 2, spring 4, threaded rod 7, base 8, coil 9 and magnet 10, one end of batten 2 is fixed in hinged mode, the other end is provided with threaded hole 6, a threaded rod 7 is equipped with in threaded hole 6, threaded rod 7 is screwed in threaded hole 6, threaded rod 7 is rotating to be fixed on base 8, in order to easy to use, batten 2 can be set to the two parts be fixedly connected with, a part is tilting section 21, another part is horizontal segment 22, one end of tilting section 21 adopts hinged mode to fix, its other end is fixedly connected with horizontal segment 22, and make tilting section 21 and horizontal direction be certain angle (generally in the majority with acute angle), tilting section 21 is fixedly installed mirror 3, for reflecting Infrared when detecting biomarker, horizontal segment offers threaded hole 6, certainly, also a nut can be fixed in addition on this horizontal segment 22, comparatively speaking, horizontal segment 22 is offered threaded hole 6, namely the structure of formula is made of one in making, can be convenient when installing and use.
In FIG, threaded hole 6 on batten 2 is in threaded rod 7 state be screwed together, namely batten 2 is screwed on threaded rod 7 with threaded hole 6, threaded rod 7 is in vertical state, when rotating under the effect of threaded rod 7 in external force, batten 2 moves up and down along threaded rod 7 jointly along with the threaded hole 6 above it, because batten 2 one end is hinged being fixed wtih, therefore, under the induced effect of threaded rod 7, batten 2 can move in a circle accordingly centered by its stiff end (for the strong point 1 in figure).In order to control/regulating the rotation of threaded rod 7, thus control/regulate the motion of batten 2 and mirror above 3 thereof, threaded rod 7 is fixed a closed coil 9, this coil 9 will extend the body of threaded rod 7, and the segment distance that stretches out, with coil 9 bottom the magnet be fixed wtih 10 is set, a part for coil 9 is overlapping in the projection in same orientation with magnet 10, like this, when passing into electric current on coil 9, the coil 9 being in closure state forms a closed loop, when having electric current to pass through in the loop that this is closed, himself produces magnetic field under electromagnetic induction effect, have an effect power each other in the magnetic field that coil 9 produces and the magnetic field of magnet 10, now, change the size of current/direction passed in coil 9 and can change the magnetic field intensity and magnetic direction that coil 9 produces, the size and Orientation in the magnetic field produced due to magnet 10 is fixing, therefore, when the size of current changed in coil 9 and/or direction, under the effect in the magnetic field of magnet 10, coil 9 rotates, because coil 9 is fixed on threaded rod 7, therefore, when coil 9 starts to rotate, threaded rod 7 can rotate along with the rotation of coil 9, threaded rod 7 is screwed in batten 2 upper screwed hole 6, therefore batten 2 also just can along with the rotation of threaded rod 7 move (for vertical direction moves up and down in figure), final batten 2 also can move along with the change of electric current in coil 9, for batten 2, because its tilting section 21 is fixed wtih in hinged mode, therefore, when passing into the change of electric current and change in batten 2 be along with coil 9, the tilting section 21 of batten 2 also will change with the angle of horizontal direction thereupon, and then, be fixed on the angle of mirror on batten 23 and horizontal direction also just along with change, the angle of the reflection ray above it also can change thereupon.
In the present invention, for the fixed form of threaded rod 7 on base 8, can select and existingly anyly make the rotatable method be fixed on base of threaded rod 7, such as, adopt on base 8, be fixedly installed a bearing, threaded rod 7 is fixed on the inner ring of bearing, makes threaded rod 7 under external force can along with the inner ring rotary motion of bearing; Also can adopt the mode that locating slot and draw-in groove combine, disclosed in patent CN99246418.8, the mode double thread bar 7 of rotary fixing structure is fixed.Other enforceable set-up mode will not enumerate at this.
As shown in Figure 1, in order to improve the adjustment sensitivity of the horizontal sextant angle of the mirror 3 on batten 2 further, batten 2 connects a spring 4, the other end of spring 4 is fixed, set an initial position, make spring 4 whole device when this initial position be in a zero point, when needing the horizontal sextant angle adjusting mirror 3, can, by the elastic force of spring 4, mirror 3 be made to be more prone to return back to initial position.Above-mentioned detailed process shows as: when passing into electric current in coil 9, magnetic field is produced in coil, under the effect of magnet 10, acting force drive threaded rod 7 common rotation that coil 9 is mutual in magnetic field, threaded rod 7 starts to rotate, batten 2 is along with the rise/fall under the rotation of threaded rod 7 of the threaded hole 6 above it, namely there is/the downtrending that rises overally in batten 2, batten 2 starts with its hinged point of fixity as axle center rotary motion, when batten 2 starts rotary motion, it also starts stretching/compressing spring 4 simultaneously, when need make batten 2 and above mirror 3 return back to the position of initial position or required setting time, when changing the size of current that passes in coil 9 accordingly or/and direction, batten 2 is when moving accordingly along with threaded rod 7, spring 4 can provide convergent force or tensile force accordingly, make batten 2 can be sensitiveer under the assistance of the acting force of spring 4, return back to initial position or desired location fast.
Fig. 2 is that the one-piece construction of spiral lift biomarker detection spectral position regulating device of the present invention overlooks view, as shown in Figure 2, under the state of overlooking, mirror 3 extends distribution along the length direction of the tilting section 21 of batten 2, threaded hole 6 is positioned on the horizontal segment 22 of batten 2, batten 2 is screwed on threaded rod 7 with threaded hole 6, the central shaft of coil 9 is identical with the bearing of trend of threaded rod 7, simultaneously, magnet 10 is positioned at the below of coil 9, note, coil 9 is made to be positioned among the magnetic field of magnet 10, after making to pass in coil 9 size of the electric current that electric current or change pass into, under the interaction in the magnetic field that coil 9 produces in the magnetic field that himself produces and magnet 10, move by the acting force of magnet 10, viewed from the orientation figure, coil 9 is under the effect of magnet 10, can rotate by axle centered by threaded rod 7, and drive threaded rod 7 common rotation.
For the setting position of spring 4 position, its a kind of embodiment can refer to Fig. 1 and Fig. 2, its one end is fixed on the horizontal segment 22 of batten 2, the other end is fixed on corresponding position (such as platform or frame are first-class), in such cases, spring 4 and the strong point 1 trend towards supporting from two ends of batten 2, in this case, all there is support at the two ends of batten 2, comparatively speaking, the position of batten 2 is comparatively stable, but due to the supporting role of spring 4, batten 2 entirety is in a kind of comparatively sensitive adjustable state, when namely applying power towards the not hinged fixing one end of batten, batten 2 can under the effect of applied force, move in a circle centered by the strong point 1, and, under the supporting role of spring 4, use the elasticity of spring 4, the athletic meeting of batten 2 is sensitiveer, more easily control and regulate.
Fig. 3 is the structural representation of the another kind of embodiment about spring setting position of spiral lift biomarker detection spectral position regulating device of the present invention, as shown in the figure, spring 4 is positioned at the hinged one end be fixed wtih of batten 2, in such cases, spring 4 and the strong point 1 trend towards supporting in one end of batten 2 and fixing, like this, batten 2 entirety is under the acting in conjunction of both the strong point 1 and spring 4, form the structure that is similar to lever, at this moment, only need apply away from the end of the strong point 1 namely a less acting force changes batten 2 initial position by leverage at batten 2, namely, when changing the electric current passed in coil 9, coil 9 rotates under the effect of magnet 10, and drive threaded rod 7 to rotate, because the threaded hole 6 on batten 2 is screwed on threaded rod 7, therefore can rise along with the rotation of threaded rod 7 or decline in one end that batten 2 is provided with threaded hole, make batten 2 entirety can with the strong point 1 for axle center rotary motion (with the vertical direction formula shown in scheming), be fixed on mirror 3 on batten 2 also along with common pivoting movement, thus play the object regulating mirror 3 and horizontal plane angle.
In the present invention, one end of batten 2 is hinged being fixed wtih, and can adopt the multiple articulated mounting and hinged fixed form that comprise hinge, hinged ball etc. herein, namely only need guarantee that batten 2 can rotate with lower friction force around the strong point 1.
As shown in figs. 1-3, the shape of magnet 10 is in scheming, (this direction is direction directly perceived in figure in the horizontal direction, the orientation that arranges of concrete material object is not limited thereto) magnet 10 is set, the concrete position with reference to magnet 10 in Fig. 2, and make its N pole and its S pole reasonable layout, make coil 9 can in the reach in magnet 10 magnetic field, move between the N pole and S pole of magnet 10, for magnet 10, in order to enough strong magnetic field can be produced, preferably use neodium magnet, stronger magnetic field can be obtained, the motion impelling the coil 9 after energising that can be powerful, its shape is not limited to the strip shown in figure, and it can also be common U magnet, bar magnet and slab-shaped magnet, or uncommon but can realize the magnet of said function.
Further, as shown in figs. 1-3, in order to improve the stability of coil 9 on threaded rod 7, and improve the adjustment sensitivity of coil 9 further, threaded rod 7 is fixed a balance device 5, this balance device 5 is arranged on threaded rod 7, its position is corresponding with coil 9, namely balance device 5 and coil 9 is made to lay respectively at the both sides of gear, and make both it, to be positioned at same level height, play certain equilibrium activity each other, at this, balance device 5 can be arranged to coiled type, its part can be made to extend threaded rod 7, so the weight of balance device 5 can be alleviated, simultaneously, balance device 5 can also by self gravitation, under leverage, good equilibrium activity is played to the position height of coil 9, namely when coil 9 is subject to the magnetic field force of magnet 10 (to be for fulcrum rotates in the horizontal direction with the point of fixity of threaded rod 7 in Fig. 1, be for fulcrum rotary motion in perpendicular in Fig. 2 with the point of fixity of threaded rod 7, identical with Fig. 1 in Fig. 3, orientation in figure is all only referred to upper position, actual direction is not limited thereto) motion time, under the effect of balance device 5, coil 9 need overcome very little power and just can break away from stationary state and move, same, when coil 9 being adjusted to initial position, only need overcome less resistance can realize, namely can realize adjusting the position of coil 9 without the need to significantly changing the electric current passed in coil 9.
For the base 8 in Fig. 1-Fig. 3, the common base assembling other parts can be used, the structure of upper and lower layer-stepping can be used, and its upper strata can be rotated in lower floor, at this moment only need threaded rod 7 be directly fixed in the superstructure of base 8, in addition, also base 8 can be arranged to adjustable height, so that determine the initial position adjusting whole device.
Fig. 4 is the using state schematic diagram of spiral lift biomarker detection spectral position regulating device of the present invention, as shown in FIG., the present invention in use, can first use not containing the detection liquid of biomarker, infrared light is used to irradiate pick-up unit, and make its reflected light be irradiated on mirror 3 by the direction shown in Fig. 2, after mirror 3 reflects, enter into spectrum acquisition device 12, the infrared ray after mirror 3 reflects is received by spectrum acquisition device 12, and determine the position of spectrum dark space, in such cases, spiral lift biomarker detection spectral position regulating device of the present invention is set as initial position, accordingly, dark space in the banded light district that spectrum acquisition device 12 place under this state is formed and banded light district is also corresponding as initial position, when change measured by detection thing time, owing to detecting the existence/concentration change of biomarker in thing, antibody in pick-up unit absorbs antigen, the reflected light detecting the infrared light irradiated changes, namely the Infrared be irradiated on mirror 3 of the present invention changes, and then after its reflection, infrared light received by spectrum acquisition device 12 sends change, its spectrum formed on spectrum acquisition device 12 also sends change thereupon, the position of its dark space formed also just can offset by relative initial position.
With reference to Fig. 4, with the infrared external reflection light of incident ray wherein for detected detection thing, with the light of its emergent light for spectrum acquisition device 12 actual received, when adjusting the position, dark space of the spectrum that spectrum acquisition device 12 is formed, during to obtain the details further about biomarker, the size of current that change passes in coil 9 is or/and direction, the intensity in the magnetic field that the coil 9 closed produces is or/and direction is also along with transmission change, like this, under the effect of magnet 10, coil 9 drives threaded rod 7 to rotate (in the balancing brake effect lower coil 9 of balance device 5 than being easier to move under the magneticaction of magnet 10), and then threaded rod 7 drives batten 2 to move by the threaded hole 6 on batten 2, i.e. batten 2 also setting in motion, the angle of mirror 3 and horizontal direction changes along with the motion of batten 2, so, the incident angle being irradiated to the incident light on mirror 3 changes, accordingly, emergence angle also changes, the angle that emergent light is irradiated on spectrum acquisition device 12 also changes, therefore also can change through the position of the dark space that the infrared ray detecting thing reflection is formed on spectrum acquisition device 12, namely the size of electric current in coil 9 is passed into or/and direction according to adjustment, the position of the dark space that corresponding control spectrum acquisition device 12 is formed, metrical information needed for being obtained by the change of this position, dark space and the change that passes into the electric current in coil 9.
It should be noted that, enforcement of the present invention is not limited to above-mentioned embodiment, such as, wherein realize the threaded rod 7 that batten 2 moves and the batten 2 screwed in the above, also by intermeshing turbine, worm screw or can be socketed the nut of installation, screw rod carries out entirety and replace, and is modified in the position of required change on demand accordingly, other art for those skilled in the art and in conjunction with existing mechanical field common practise all very easyly can make above-mentioned variation; And in the present invention, the position of spring 4 is also not limited to the position shown in figure, also can be moved other correct position, is as the criterion with easy to use.
By reference to the accompanying drawings the specific embodiment of the present invention is explained in detail above, but the present invention is not limited to above-mentioned embodiment, in the ken that those skilled in the art possess, various change can also be made under the prerequisite not departing from present inventive concept.