CN104784628A - Traditional Chinese medicine composition for treating hepatitis B - Google Patents
Traditional Chinese medicine composition for treating hepatitis B Download PDFInfo
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- CN104784628A CN104784628A CN201510117927.8A CN201510117927A CN104784628A CN 104784628 A CN104784628 A CN 104784628A CN 201510117927 A CN201510117927 A CN 201510117927A CN 104784628 A CN104784628 A CN 104784628A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating hepatitis B; the traditional Chinese medicine composition is prepared by compatibility of the following drug components: 6-9 parts of radix astragali, 3-9 parts of fructus ligustri lucidi, 3-6 parts of polygonum cuspidatum, 5-10 parts of oldenlandia diffusa, 2-4 parts of paris polyphylla, 3-9 parts of radix bupleuri, 5-10 parts of polygonatum sibiricum, 3-9 parts of wolfberry, 3-9 parts of radix aucklandiae, 6-9 parts of white paeony root, 3-6 parts of rhizoma smilacis glabrae, 3-6 parts of angelica sinensis, 5-10 parts of portulaca grandiflora hook., 5-10 parts of verbena officinalis, 1-3 parts of rose flower, 2-5 parts of fruit of fiverleaf akebia, 2-4 parts of radix curcumae, 1-6 parts of licorice, 3-6 parts of schisandra chinensis, 6-9 parts of dilatate microsorium herb, 3-6 parts of radix salviae miltiorrhizae, 3-6 parts of codonopsis pilosula, and 5-10 parts of capillary artemisia. The composition is prepared by adopting the pure traditional Chinese medicines. Through clinical verification, the composition has a significant curative effect on hepatitis B and does not have any side effect on patients, and the patients cannot produce drug dependence with long-time medicine taking.
Description
Technical field
The invention belongs to medical art, relate to a kind of Chinese medicine composition of disease therapy, be specifically related to a kind of Chinese medicine composition for the treatment of hepatitis B.
Background technology
Hepatitis B is caused by hepatitis B virus (HBV), based on liver inflammatory pathological changes, and can cause a kind of disease of multiple organ injury.Hepatitis B is widely current in countries in the world, and main infringement child and person between twenty and fifty, small number of patients can be converted into liver cirrhosis or hepatocarcinoma.Therefore, it has become the worldwide disease of serious threat human health, a kind of disease that Ye Shi China current popular is the most extensive, hazardness is the most serious.Hepatitis B, without certain epizootic modeling, all can be fallen ill throughout the year, but belong to distributes more.Hepatitis B sickness rate is in the trend obviously increased in recent years.Current treatment hepatitis B is mainly by antiviral therapy, and its drug price is relatively expensive, and side effect is comparatively large, Long-term taking medicine, all can cause infringement to a certain degree, also easily form the dependency to medicine and Drug resistance to the liver of patient, kidney and other organs.For seeking the resistance problems of better Anti-viral Treatment and solution nucleoside (acid) analog, many scholars have all carried out various different trial.Disclose the Chinese medicine of a lot for the treatment of hepatitis B in prior art, Chinese medicine preparation is more and more subject to the favor of patient, but there is uncertain therapeutic efficacy and cut, and the shortcoming that therapeutic effect is not good, brings the dual injury on body & mind to patient.
Summary of the invention
The present invention is directed to the technological deficiency that prior art treatment hepatitis B exists, object is to provide a kind of Chinese medicine composition for the treatment of hepatitis B, and this Chinese medicine is without any side effects, and patient's long-term taking can not produce the dependency to medicine, has very significant therapeutical effect.
The present invention realizes especially by following technical scheme:
A kind of Chinese medicine composition for the treatment of hepatitis B, comprise following active component: the Radix Astragali 6 ~ 9 parts, Fructus Ligustri Lucidi 3 ~ 9 parts, Rhizoma Polygoni Cuspidati 3 ~ 6 parts, Herba Hedyotidis Diffusae 5 ~ 10 parts, Aicis galericulata worm 2 ~ 4 parts, Radix Bupleuri 3 ~ 9 parts, Rhizoma Polygonati 5 ~ 10 parts, Fructus Lycii 3 ~ 9 parts, the Radix Aucklandiae 3 ~ 9 parts, the Radix Paeoniae Alba 6 ~ 9 parts, Rhizoma Smilacis Glabrae 3 ~ 6 parts, Radix Angelicae Sinensis 3 ~ 6 parts, spun gold Cuculus polioephalus 5 ~ 10 parts, Herba Verbenae 5 ~ 10 parts, Flos Rosae Rugosae 1 ~ 3 part, beautiful stand 2 ~ 5 parts, Radix Curcumae 2 ~ 4 parts, 1 ~ 6 part, Radix Glycyrrhizae, Fructus Schisandrae Chinensis 3 ~ 6 parts, Radix Salviae Miltiorrhizae 3 ~ 6 parts, Radix Codonopsis 3 ~ 6 parts, Herba Artemisiae Scopariae 5 ~ 10 parts, Microsorium dilatatum (Bedd.) Sledge 6 ~ 9 parts.
A kind of Chinese medicine composition for the treatment of hepatitis B, preferably include following active component: the Radix Astragali 6 parts, Fructus Ligustri Lucidi 3 parts, Rhizoma Polygoni Cuspidati 3 parts, Herba Hedyotidis Diffusae 5 parts, Aicis galericulata worm 2 parts, Radix Bupleuri 3 parts, Rhizoma Polygonati 5 parts, Fructus Lycii 3 parts, the Radix Aucklandiae 3 parts, the Radix Paeoniae Alba 6 parts, Rhizoma Smilacis Glabrae 3 parts, Radix Angelicae Sinensis 3 parts, spun gold Cuculus polioephalus 5 parts, Herba Verbenae 5 parts, Flos Rosae Rugosae 1 part, beautiful stand 2 parts, Radix Curcumae 2 parts, 1 part, Radix Glycyrrhizae, Fructus Schisandrae Chinensis 3 parts, Microsorium dilatatum (Bedd.) Sledge 6 parts, Radix Salviae Miltiorrhizae 3 parts, Radix Codonopsis 3 parts, Herba Artemisiae Scopariae 5 parts.
The present composition can be processed into acceptable dosage form in any sterilization on demand, its preparation can be prepared by common processing method known in those skilled in the art, after mixing with liquid flux or solid carrier by active component, then add one or more in filler, binding agent, wetting agent, disintegrating agent, absorption enhancer, solvent, surfactant, flavouring agent, antiseptic, lubricant, sweeting agent or pigment.
The present composition is made tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, decoction, oral liquid, is sucked agent, granule, electuary, pill, powder, unguentum, sublimed preparation, suspensoid, solution, injection, suppository, ointment, plaster, cream, spray, drop, drop pill or patch.
Compositions of the present invention can by user before use through diluting or directly using.
The present composition is as the application of preparation treatment hepatitis B medicine.
The Radix Astragali in the present invention, Radix Codonopsis, Radix Glycyrrhizae, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Rhizoma Polygonati, Fructus Ligustri Lucidi, Fructus Lycii vigorate qi and replenish the blood YIN nourishing are to treatment liver deficiency of both vital energy and Yin, and deficiency of YIN-blood has significant curative effect.
Rhizoma Polygoni Cuspidati in the present invention, Herba Hedyotidis Diffusae, Aicis galericulata worm, spun gold Cuculus polioephalus, Herba Verbenae, spun gold Cuculus polioephalus, Herba Sedi Linearis, to heat-clearing and toxic substances removing, suppress virus replication to have significant curative effect.
Rhizoma Smilacis Glabrae in the present invention, Herba Artemisiae Scopariae, Radix Salviae Miltiorrhizae, Fructus Schisandrae Chinensis are to damp eliminating, and scavenging free radicals has significant curative effect.
Radix Bupleuri in the present invention, Radix Curcumae, Flos Rosae Rugosae, beautiful stand, the Radix Aucklandiae have resolving depression effect of regulating the flow of vital energy significantly.
Beneficial effect of the present invention is made for adopting pure Chinese medicine, through clinical verification, has significant curative effect to all kinds of hepatic disease, and without any side effects to patient, and patient's Long-term taking medicine also can not produce drug dependence.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described further, the following stated, only to preferred embodiment of the present invention, not do other forms of restriction to the present invention, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed to the Equivalent embodiments of equal change.Everyly do not depart from the present invention program's content, any simple modification done following examples according to technical spirit of the present invention or equivalent variations, all drop in protection scope of the present invention.
Embodiment 1
Treat a Chinese medicine for hepatitis B, formed by agents component compatibility:
The Radix Astragali 6 parts, Fructus Ligustri Lucidi 3 parts, Rhizoma Polygoni Cuspidati 3 parts, Herba Hedyotidis Diffusae 5 parts, Aicis galericulata worm 2 parts, Radix Bupleuri 3 parts, Rhizoma Polygonati 5 parts, Fructus Lycii 3 parts, the Radix Aucklandiae 3 parts, the Radix Paeoniae Alba 6 parts, Rhizoma Smilacis Glabrae 3 parts, Radix Angelicae Sinensis 3 parts, spun gold Cuculus polioephalus 5 parts, Herba Verbenae 5 parts, Flos Rosae Rugosae 1 part, beautiful stand 2 parts, Radix Curcumae 2 parts, 1 part, Radix Glycyrrhizae, Fructus Schisandrae Chinensis 3 parts, Microsorium dilatatum (Bedd.) Sledge 6 parts, Radix Salviae Miltiorrhizae 3 parts, Radix Codonopsis 3 parts, Herba Artemisiae Scopariae 5 parts.
Chinese medicine of the present invention is good with decoction oral, and concrete preparation method is: cleaned by above-mentioned all Chinese medicine, sterilize, then put into crock, pure water is put to not having medicine general, big fire decocts three times, then adopts little fire to decoct 6 hours, and medicine juice filtered through gauze is loaded vial encapsulation.
Chinese drugs agentia instructions of taking of the present invention is: oral, within 1st, takes three times, each 3 ~ 5 milliliters, within one week, is a course for the treatment of, must takes more than two courses for the treatment of continuously.
Embodiment 2
A kind of Chinese medicine for the treatment of hepatitis B, formed by agents component compatibility: the Radix Astragali 5 parts, Fructus Ligustri Lucidi 3 parts, Rhizoma Polygoni Cuspidati 3 parts, Herba Hedyotidis Diffusae 6 parts, Aicis galericulata worm 2 parts, Radix Bupleuri 3 parts, Rhizoma Polygonati 4 parts, Fructus Lycii 3 parts, the Radix Aucklandiae 3 parts, the Radix Paeoniae Alba 6 parts, Rhizoma Smilacis Glabrae 3 parts, Radix Angelicae Sinensis 3 parts, spun gold Cuculus polioephalus 5 parts, Herba Verbenae 5 parts, Flos Rosae Rugosae 1 part, beautiful stand 2 parts, Radix Curcumae 2 parts, 1 part, Radix Glycyrrhizae, Fructus Schisandrae Chinensis 3 parts, Microsorium dilatatum (Bedd.) Sledge 6 parts, Radix Salviae Miltiorrhizae 3 parts, Radix Codonopsis 3 parts, Herba Artemisiae Scopariae 9 parts.
Chinese medicine of the present invention is oral with unguentum is good, concrete preparation method is: cleaned by above-mentioned all Chinese medicine, sterilize, then putting into Chinese medicine Manufacturing medicine extract machine, pure water being put 1 times to not having medicine, make ointment by Chinese medicine cream behaviour code, ointment is distributed into vial encapsulation.
Chinese medicine ointment instructions of taking of the present invention is: oral, within 1st, takes three times, each 3 ~ 5 milliliters, within one week, is a course for the treatment of, must takes more than two courses for the treatment of continuously.
Embodiment 3
Treat a Chinese medicine for hepatitis B, it is characterized in that, formed by agents component compatibility:
The Radix Astragali 6 parts, Rhizoma Polygoni Cuspidati 3 parts, Herba Hedyotidis Diffusae 6 parts, Aicis galericulata worm 3 parts, Radix Bupleuri 3 parts, Rhizoma Smilacis Glabrae 3 parts, spun gold Cuculus polioephalus 3 parts, Herba Verbenae 3 parts, 3 parts, Radix Glycyrrhizae, Fructus Schisandrae Chinensis 3 parts, Herba Artemisiae Scopariae 5 parts, Microsorium dilatatum (Bedd.) Sledge 6 parts.
Chinese medicine of the present invention is good with capsule oral, and concrete preparation method is: cleaned by above-mentioned all Chinese medicine, sterilize, incapsulate encapsulation after former medicated powder broken mistake 120 order weighed up.
Chinese medicinal capsule instructions of taking of the present invention is: oral, within 1st, takes three times, each 3 ~ 5, within one week, is a course for the treatment of, must takes more than two courses for the treatment of continuously.
Embodiment 4 clinical practice
The Chinese medicine composition of invention effectively can treat hepatitis B.Clinical experiment for many years by carrying out countless patient, its result all achieves significant curative effect.Now with the situation of 100 routine patient's pertinent clinical treatments, details are as follows.
Clinical data: collect 100 the typical patients of symptom suffering from hepatitis B throughout the country, carry out the clinical experiment of Chinese medicine composition of the present invention.These 100 patient male 64 people, women 36 people, oldest 35 years old, minimum 19 years old, 26 years old mean age.
Therapeutic Method: treat according to embodiment 1 ~ 3 gained preparation, oral, within 1st, take three times, each 3 ~ 5 milliliters/, within one week, be a course for the treatment of, more than two courses for the treatment of must be taken continuously, treat observe the curative effect after 8 courses for the treatment of, follow up a case by regular visits to 1 year.Set up matched group simultaneously, take flunarizine.
Criterion of therapeutical effect: carry out classification according to the symptom variation situation of patient and cardinal symptom.
Recovery from illness: (liver function, 2 to half in laboratory examination.HBV ~ DNA) completely normal, somatization symptom disappears completely.
Effective: (liver function, 2 to half in laboratory examination.HBV ~ DNA) close to normal, somatization symptom significantly alleviates.
Effective: (liver function, 2 to half in laboratory examination.HBV ~ DNA) take a turn for the better to some extent, somatization symptom alleviates to some extent.
Invalid: (liver function, 2 to half in laboratory examination.HBV ~ DNA) do not take a turn for the better, somatization symptom does not alleviate.
Therapeutic outcome statistics is as table 1:
Table 1 clinical treatment outcome
Standard | Embodiment 1 | Embodiment 2 | Embodiment 3 | Matched group |
Recovery from illness | 75 people | 76 people | 80 people | 61 |
Effective | 19 people | 21 people | 16 people | 20 |
Effectively | 4 people | 3 people | 3 people | 12 |
Invalid | 2 people | 0 people | 1 people | 7 |
Model case 1
Zhao, female, 34 years old, suffer from hepatitis B 5 years, take antiviral class Western medicine, DeGrain, take latter two moon of medicine of the present invention, symptom was obviously improved, and after taking three months, Hepatitis B virus is all turned out cloudy always.After follow up a case by regular visits to 1 year, the state of an illness is without recurrence.
Model case 2
Xu certain, man, 23 years old, student, checked out great three positive when having a medical check-up, and took medicine of the present invention after 3 months, and look into liver function normal, Hepatitis B virus is all turned out cloudy, after follow up a case by regular visits to 1 year, the state of an illness is without recurrence.
Claims (4)
1. treat the Chinese medicine composition of hepatitis B for one kind, it is characterized in that: comprise following active component: the Radix Astragali 6 ~ 9 parts, Fructus Ligustri Lucidi 3 ~ 9 parts, Rhizoma Polygoni Cuspidati 3 ~ 6 parts, Herba Hedyotidis Diffusae 5 ~ 10 parts, Aicis galericulata worm 2 ~ 4 parts, Radix Bupleuri 3 ~ 9 parts, Rhizoma Polygonati 5 ~ 10 parts, Fructus Lycii 3 ~ 9 parts, the Radix Aucklandiae 3 ~ 9 parts, the Radix Paeoniae Alba 6 ~ 9 parts, Rhizoma Smilacis Glabrae 3 ~ 6 parts, Radix Angelicae Sinensis 3 ~ 6 parts, spun gold Cuculus polioephalus 5 ~ 10 parts, Herba Verbenae 5 ~ 10 parts, Flos Rosae Rugosae 1 ~ 3 part, beautiful stand 2 ~ 5 parts, Radix Curcumae 2 ~ 4 parts, 1 ~ 6 part, Radix Glycyrrhizae, Fructus Schisandrae Chinensis 3 ~ 6 parts, Radix Salviae Miltiorrhizae 3 ~ 6 parts, Radix Codonopsis 3 ~ 6 parts, Herba Artemisiae Scopariae 5 ~ 10 parts, Microsorium dilatatum (Bedd.) Sledge 6 ~ 9 parts.
2. a kind of Chinese medicine composition for the treatment of hepatitis B according to claim 1, it is characterized in that comprising following active component: the Radix Astragali 6 parts, Fructus Ligustri Lucidi 3 parts, Rhizoma Polygoni Cuspidati 3 parts, Herba Hedyotidis Diffusae 5 parts, Aicis galericulata worm 2 parts, Radix Bupleuri 3 parts, Rhizoma Polygonati 5 parts, Fructus Lycii 3 parts, the Radix Aucklandiae 3 parts, the Radix Paeoniae Alba 6 parts, Rhizoma Smilacis Glabrae 3 parts, Radix Angelicae Sinensis 3 parts, spun gold Cuculus polioephalus 5 parts, Herba Verbenae 5 parts, Flos Rosae Rugosae 1 part, beautiful stand 2 parts, Radix Curcumae 2 parts, 1 part, Radix Glycyrrhizae, Fructus Schisandrae Chinensis 3 parts, Microsorium dilatatum (Bedd.) Sledge 6 parts, Radix Salviae Miltiorrhizae 3 parts, Radix Codonopsis 3 parts, Herba Artemisiae Scopariae 5 parts.
3. a kind of Chinese medicine composition for the treatment of hepatitis B according to claim 1 and 2, is characterized in that: compositions makes decoction, capsule or unguentum.
4. Chinese medicine composition according to claim 1 is as the application of preparation treatment hepatitis B medicine.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105770769A (en) * | 2016-05-06 | 2016-07-20 | 兖矿集团有限公司总医院 | Traditional Chinese medicinal composition for treating hepatitis B and preparation method as well as application thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1176123A (en) * | 1996-02-15 | 1998-03-18 | 邵阳县中医院 | Medicine for chronic hepatitis B and its preparation |
US20040052876A1 (en) * | 2002-09-13 | 2004-03-18 | Industrial Technology Research Institute | Composition for treating diseased liver |
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- 2015-03-18 CN CN201510117927.8A patent/CN104784628A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1176123A (en) * | 1996-02-15 | 1998-03-18 | 邵阳县中医院 | Medicine for chronic hepatitis B and its preparation |
US20040052876A1 (en) * | 2002-09-13 | 2004-03-18 | Industrial Technology Research Institute | Composition for treating diseased liver |
Non-Patent Citations (2)
Title |
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吴平凡等: "《名中医验方集成》", 31 December 1998, 人民军医出版社 * |
胡明宁等: ""黄白归虎汤"治慢性乙肝35例", 《四川中医》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105770769A (en) * | 2016-05-06 | 2016-07-20 | 兖矿集团有限公司总医院 | Traditional Chinese medicinal composition for treating hepatitis B and preparation method as well as application thereof |
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