CN104771679A - Traditional Chinese medicine for treating uterine prolapse - Google Patents

Traditional Chinese medicine for treating uterine prolapse Download PDF

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Publication number
CN104771679A
CN104771679A CN201510160005.5A CN201510160005A CN104771679A CN 104771679 A CN104771679 A CN 104771679A CN 201510160005 A CN201510160005 A CN 201510160005A CN 104771679 A CN104771679 A CN 104771679A
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parts
chinese medicine
uterine prolapse
fructus
traditional chinese
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CN201510160005.5A
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CN104771679B (en
Inventor
李晓冰
郑明常
王娜梅
张慧俭
李昱金
赵云芳
李瑞琴
展俊平
李宁
程凯
王君明
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Henan University of Traditional Chinese Medicine HUTCM
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Henan University of Traditional Chinese Medicine HUTCM
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Abstract

The invention relates to a traditional Chinese medicine for treating uterine prolapse. The traditional Chinese medicine is capable of effectively solving the drug use problem of uterine prolapse. The technical scheme for solving the drug use problem is as follows: the traditional Chinese medicine is prepared from the following medicinal raw materials in parts by weight: 5-15 parts of cortex acanthopanacis, 10-30 parts of codonopsis pilosula, 10-20 parts of white hyacinth bean, 5-10 parts of cimicifugae foetidae, 5-15 parts of cuttlebone, 5-15 parts of red halloysite, 3-10 parts of schisandra chinensis, 5-15 parts of the bark of eucommia, 5-15 parts of fructus alpiniae oxyphyllae, and 5-15 parts of motherwort fruit. The traditional Chinese medicine disclosed by the invention is abundant in raw materials, low in cost, scientific in components, reasonable in compatibility and supported with each other; all the drugs have the effects of invigorating spleen-stomach, replenishing qi, ascending qi, reinforcing vital essence and inducing astringency; the traditional Chinese medicine is effectively used for treating uterine prolapse; and the traditional Chinese medicine is good in curative effect and safe in medical use and is a major innovation of medicaments for treating uterine prolapse.

Description

A kind of Chinese medicine for the treatment of uterine prolapse
Technical field
The present invention relates to field of medicaments, particularly a kind of Chinese medicine for the treatment of uterine prolapse.
Background technology
Uterine prolapse refers to that uterus declines from normal position along vagina, and it is below horizontal that cervical orifice reaches ischial spine, and even uterus all emerges in beyond vaginal orifice.Be apt to occur in postpartum women.Clinically main manifestations be the soreness of waist, abdominal part tenesmus, work and walking after symptom can increase the weight of, the related symptoms such as even more serious occurred frequent micturition or dysuria, urine retention, urinary incontinence and leucorrhoea grow in quantity.Patient Duo Yin overstrain, fecund, damage spleen kidney, deficiency of spleen-QI is sinking of QI of middle-JIAO then, and kidney qi loss causes dai channel and fails to keep an appointment, the debility of CHONG and REN meridians, unablely maintains uterus, and uterine ligaments relaxes, and uterus loses suspention and sends out primary disease.Western medical treatment is based on supporting treatment, pessulum or operative treatment, and clinical efficacy is not obvious.Therefore, the improvement and bring new ideas for the treatment of on uterine prolapse medicine is the problem needing solution at present badly.
Summary of the invention
For above-mentioned situation, for solving the defect of prior art, the object of the present invention is just to provide a kind of Chinese medicine for the treatment of uterine prolapse, effectively can solve the medication problem of uterine prolapse.
The technical scheme that the present invention solves is, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt the material medicine of following weight parts to make: Cortex Acanthopancis 5-15 part, Radix Codonopsis 10-30 part, Semen Lablab Album 10-20 part, Rhizoma Cimicifugae 5-10 part, Endoconcha Sepiae 5-15 part, Halloysitum Rubrum 5-15 part, Fructus Schisandrae Chinensis 3-10 part, Cortex Eucommiae 5-15 part, Fructus Alpiniae Oxyphyllae 5-15 part and Fructus Leonuri 5-15 part.
Abundant raw material of the present invention, cheap, component science, reasonable compatibility, supports mutually, and all medicines play invigorating the spleen and replenishing QI ascending, the first astringent or styptic treatment for spontaneous sweating effect of training altogether, are effective to treat uterine prolapse, good effect, drug safety, is that on treatment uterine prolapse medicine innovates greatly.
Detailed description of the invention
Below in conjunction with embodiment, the specific embodiment of the present invention is described in further detail.
Embodiment 1
The present invention in the specific implementation, can be made up of the material medicine of following weight parts: Cortex Acanthopancis 5 parts, Radix Codonopsis 30 parts, Semen Lablab Album 10 parts, Rhizoma Cimicifugae 10 parts, Endoconcha Sepiae 5 parts, Halloysitum Rubrum 15 parts, Fructus Schisandrae Chinensis 3 parts, the Cortex Eucommiae 15 parts, Fructus Alpiniae Oxyphyllae 5 parts and Fructus Leonuri 15 parts.
Embodiment 2
The present invention in the specific implementation, also can be made up of the material medicine of following weight parts: Cortex Acanthopancis 10 parts, Radix Codonopsis 20 parts, Semen Lablab Album 15 parts, Rhizoma Cimicifugae 7 parts, Endoconcha Sepiae 10 parts, Halloysitum Rubrum 10 parts, Fructus Schisandrae Chinensis 6 parts, the Cortex Eucommiae 10 parts, Fructus Alpiniae Oxyphyllae 10 parts and Fructus Leonuri 10 parts.
Embodiment 3
The present invention in the specific implementation, also can be made up of the material medicine of following weight parts: Cortex Acanthopancis 15 parts, Radix Codonopsis 10 parts, Semen Lablab Album 20 parts, Rhizoma Cimicifugae 5 parts, Endoconcha Sepiae 15 parts, Halloysitum Rubrum 5 parts, Fructus Schisandrae Chinensis 10 parts, the Cortex Eucommiae 5 parts, Fructus Alpiniae Oxyphyllae 15 parts and Fructus Leonuri 5 parts.
Embodiment 4
The present invention in the specific implementation, also can be made up of the material medicine of following weight parts: Cortex Acanthopancis 5-10 part, Radix Codonopsis 10-20 part, Semen Lablab Album 10-15 part, Rhizoma Cimicifugae 5-7 part, Endoconcha Sepiae 5-10 part, Halloysitum Rubrum 5-10 part, Fructus Schisandrae Chinensis 3-6 part, Cortex Eucommiae 5-10 part, Fructus Alpiniae Oxyphyllae 5-10 part and Fructus Leonuri 5-10 part.
Embodiment 5
The present invention in the specific implementation, also can be made up of the material medicine of following weight parts: Cortex Acanthopancis 11-15 part, Radix Codonopsis 21-30 part, Semen Lablab Album 16-20 part, Rhizoma Cimicifugae 8-10 part, Endoconcha Sepiae 11-15 part, Halloysitum Rubrum 11-15 part, Fructus Schisandrae Chinensis 7-10 part, Cortex Eucommiae 11-15 part, Fructus Alpiniae Oxyphyllae 11-15 part and Fructus Leonuri 11-15 part.
Chinese medicine of the present invention can according to the needs of clinical practice, preparation method makes decoction routinely, powder (powder), tablet, granule, pill, capsules etc. are suitable for the various dosage forms applied, provide the decoction that conventional method is made below, specifically: first by Cortex Acanthopancis, Radix Codonopsis, Semen Lablab Album, Rhizoma Cimicifugae, Endoconcha Sepiae, Halloysitum Rubrum, Fructus Schisandrae Chinensis, the Cortex Eucommiae, Fructus Alpiniae Oxyphyllae and Fructus Leonuri mix, put into medicinal cupping, add water to submerge, soak 30-60min, intense fire decocts to boiling, use slow fire boiling 20-30min instead, filter, obtain filtrate, filtering residue adds water to submerge again, intense fire decocts to boiling, use slow fire boiling 20-30min instead, filter, obtain filtrate, merge twice filtrate, mixing.
In instant component:
Cortex Acanthopancis: pungent, bitter, temperature.Return liver, kidney channel.Wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening.For rheumatic arthralgia, muscles and bones flaccidity is soft, children's's walking retardation in children, and body void is weak, edema, beriberi.
Radix Codonopsis: sweet is flat.Return spleen, lung meridian.Invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
Semen Lablab Album: sweet, tepor.Return spleen, stomach warp.Invigorating the spleen for eliminating dampness, and in relieve summer heat.For weakness of the spleen and stomach, inappetence, diarrhea, leukorrhagia, heat-damp in summer is vomited and diarrhoea, abdominal distention uncomfortable in chest.
Rhizoma Cimicifugae: pungent, micro-sweet, is slightly cold.Return lung, spleen, stomach, large intestine channel.Deliver rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.For headache due to pathogenic wind-heat, toothache, aphtha, laryngopharynx swelling and pain, measles without adequate eruption, YANG toxin syndrome sends out speckle; Proctoptosis, uterine prolapse.
Endoconcha Sepiae: salty, puckery, temperature.Return spleen, kidney channel.Astringing to arrest bleeding, relieving leukorrhea by astringents, antacid, sore.For acid regurgitation of having a stomachache, hematemesis and epistaxis, metrorrhagia is had blood in stool, emission and spermatorrhea, leucorrhea with red and white discharge; Peptic Ulcers.External treatment bleeding due to trauma, the many pus of skin ulcer.
Halloysitum Rubrum: sweet, sour, puckery, temperature.Return stomach, large intestine channel.Astringing intestine to stop diarrhea, hemostasis, promoting tissue regeneration and ulcer healing.For chronic diarrhea chronic dysentery, fecal blood, bleeding not during menses; External treatment skin infection is not held back, and eczema pus is contaminated.
Fructus Schisandrae Chinensis: sour, sweet, temperature.Return lung, the heart, kidney channel.Restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
The Cortex Eucommiae: sweet, temperature.Return liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, antiabortive.For lumbago due to renal deficiency, muscles and bones is unable, blood leaking in gestation, frequent fetal movement; Hypertension.
Fructus Alpiniae Oxyphyllae: acrid in the mouth; Warm in nature.Return spleen, kidney channel.Warming spleen and stopping diarrhaly take the photograph saliva; Warming the kidney reducing urination controlling nocturnal emission with astringent drugs.Main Deficiency and coldness of spleen and stomach; Vomiting; Have loose bowels; Coldly in abdomen to educate; The many salivas of mouth; Enuresis due to deficiency of the kidney; Frequent micturition; Seminal emission; Nebulousurine
Fructus Leonuri: pungent, bitter, is slightly cold.GUIXIN bag, Liver Channel.Promoting blood flow to regulate menstruation, liver heat removing and eyesight improving.For menoxenia, amenorrhea, dysmenorrhea, cataract, dizzy distending pain.
The Chinese medicine composition that the present invention treats uterine prolapse is based on fundamental Chinese medicine theory, develops the Chinese medicine composition with replenishing QI to invigorate the spleen ascending, the first astringent or styptic treatment for spontaneous sweating effect of training.Radix Codonopsis, Semen Lablab Album invigorating the spleen and benefiting QI in prescription; Rhizoma Cimicifugae yang invigorating; Endoconcha Sepiae, Halloysitum Rubrum, Fructus Schisandrae Chinensis convergence take off admittedly; Cortex Acanthopancis, the Cortex Eucommiae, Fructus Alpiniae Oxyphyllae kidney tonifying training unit.Fructus Leonuri is motherwort seed, containing leonurine first, can strengthen muscular contraction force in excited uterus.Full side gathers replenishing QI to invigorate the spleen ascending, the astringent or styptic treatment for spontaneous sweating effect of training unit altogether, utilizes the comprehensive function treatment uterine prolapse of every Chinese medicine, harmless to human non-toxic, good effect, drug safety, and obtains sufficient proof through clinical experiment, and pertinent clinical experimental data is as follows:
Chinese medicine of the present invention for decoction,
1, physical data
In 80 routine patients, be divided into treatment group and matched group at random.Treatment group 40 example, 33 ~ 64 years old age, average (46.27 ± 11.52) year; Pregnant time 1 ~ 3 time, average (1.91 ± 0.57) are secondary; The course of disease 3 ~ 16 years, average (7.1 ± 1.85) year; Uterine prolapse I degree of 24 example, II degree of 16 example.Matched group 40 example, 30 ~ 68 years old age, average (47.42 ± 8.75) year; Pregnant time 1 ~ 4 time, average (1.87 ± 0.42) are secondary; The course of disease 2 ~ 15 years, average (8.5 ± 1.98) year; Uterine prolapse I degree of 23 example, II degree of 17 example.2 groups of data are through statistical procedures, and in age, the state of an illness, difference there are no significant meaning (P>0.05), has comparability.
, case inclusive criteria
Selected patient is First episode, and without regular treatment; With anterior vaginal wall or descent vaginae posterior; Get rid of uterine prolapse with severe complication persons such as the serious heart, brain, kidneys; Uterine prolapse is with Pelvic floor atrophy person; Uterine prolapse companion severe cervical canker sore, infection suppurates and congenital cervix uteri prolong elder.
, therapeutic scheme
Treatment group: take Chinese medicine of the present invention, sooner or later respectively once, decoction being taken warmly, each 200-300ml.
Matched group: adopt supporting treatment, comprise reinforcement nutrition, reasonable arrangement is had a rest and work, avoid heavy physical labour, avoid the action of increase abdominal pressures such as standing for a long time or squat down, hold one's breath, keep free movement of the bowels, keep perineal position to clean, actively carry out gymnastic to temper pelvic floor muscles and abdominal wall muscle.As enjoin patient's row shrink anus motion, namely anus one contract one loosen do, every day 2 times, each 10 minutes; Row knee chest position is practised: emptying urine, loosens one's waistband, and whole body loosens, and kneel on hardboard bed, head is put in bed, and face turns to side, the micro-Qu Qianshen of two-arm, and buttocks is raised with thigh rectangular, each 1 time sooner or later, each 10 minutes.
Treatment group and matched group are 30 days the course for the treatment of, observe the curative effect after the course for the treatment of.
, efficacy assessment standard
Cure: transference cure, more than cervix uteri mouth location restore ischial spine level;
Effective: transference cure, uterus is returned and is contained in intravaginal, and cervical orifice is close to ischial spine level;
Effective: symptom comparatively before take a turn for the better, uterus is returned and is received vagina situation and slightly improve;
Invalid: symptom without improvement, uterus return receive vagina situation comparatively treat before without improve.
, statistical procedures
Adopt SPSS13.0 statistical software, enumeration data adopts x2 inspection, and ranked data adopt Ridit inspection.
As can be seen from Table 1, treatment group recovery from illness 15 example, effective 13 examples, effective 10 examples, invalid 2 examples, total effective rate is 95%; Matched group recovery from illness 6 example, effective 9 examples, effective 13 examples, invalid 12 examples, total effective rate is 70%.Treatment group compares with matched group, recovery from illness, and invalid and total effective rate has remarkable significant difference;
Table 1 liang group Clinical efficacy comparison
Compare with matched group, * P < 0.05, * * P < 0.01
Chinese medicine composition of the present invention is through making other dosage forms; all achieve identical or close result in an experiment; will not enumerate, prevent tired stating, and; what the application's request was protected is Chinese medicine composition (component invention); and do not lie in dosage form or preparation method, and therefore, arbitrary dosage form that all employing the application Chinese medicine compositions are made; and be used for the treatment of the medicine of uterine prolapse, all belong to the scope of the application's protection.
conclusion
Component science of the present invention, abundant raw material, cheap, reasonable compatibility, mutual support, all medicines play replenishing QI to invigorate the spleen ascending, the first astringent or styptic treatment for spontaneous sweating effect of training altogether, are effective to treat uterine prolapse, good effect, drug safety, effective percentage, up to 95%, is that one on Chinese medicine is innovated greatly, has actual clinical meaning.

Claims (7)

1. treat the Chinese medicine of uterine prolapse for one kind, it is characterized in that, be made up of the material medicine of following weight parts: Cortex Acanthopancis 5-15 part, Radix Codonopsis 10-30 part, Semen Lablab Album 10-20 part, Rhizoma Cimicifugae 5-10 part, Endoconcha Sepiae 5-15 part, Halloysitum Rubrum 5-15 part, Fructus Schisandrae Chinensis 3-10 part, Cortex Eucommiae 5-15 part, Fructus Alpiniae Oxyphyllae 5-15 part and Fructus Leonuri 5-15 part.
2. the Chinese medicine for the treatment of uterine prolapse according to claim 1, it is characterized in that, be made up of the material medicine of following weight parts: Cortex Acanthopancis 5 parts, Radix Codonopsis 30 parts, Semen Lablab Album 10 parts, Rhizoma Cimicifugae 10 parts, Endoconcha Sepiae 5 parts, Halloysitum Rubrum 15 parts, Fructus Schisandrae Chinensis 3 parts, the Cortex Eucommiae 15 parts, Fructus Alpiniae Oxyphyllae 5 parts and Fructus Leonuri 15 parts.
3. the Chinese medicine for the treatment of uterine prolapse according to claim 1, it is characterized in that, be made up of the material medicine of following weight parts: Cortex Acanthopancis 10 parts, Radix Codonopsis 20 parts, Semen Lablab Album 15 parts, Rhizoma Cimicifugae 7 parts, Endoconcha Sepiae 10 parts, Halloysitum Rubrum 10 parts, Fructus Schisandrae Chinensis 6 parts, the Cortex Eucommiae 10 parts, Fructus Alpiniae Oxyphyllae 10 parts and Fructus Leonuri 10 parts.
4. the Chinese medicine for the treatment of uterine prolapse according to claim 1, it is characterized in that, be made up of the material medicine of following weight parts: Cortex Acanthopancis 15 parts, Radix Codonopsis 10 parts, Semen Lablab Album 20 parts, Rhizoma Cimicifugae 5 parts, Endoconcha Sepiae 15 parts, Halloysitum Rubrum 5 parts, Fructus Schisandrae Chinensis 10 parts, the Cortex Eucommiae 5 parts, Fructus Alpiniae Oxyphyllae 15 parts and Fructus Leonuri 5 parts.
5. the Chinese medicine for the treatment of uterine prolapse according to claim 1, it is characterized in that, be made up of the material medicine of following weight parts: Cortex Acanthopancis 5-10 part, Radix Codonopsis 10-20 part, Semen Lablab Album 10-15 part, Rhizoma Cimicifugae 5-7 part, Endoconcha Sepiae 5-10 part, Halloysitum Rubrum 5-10 part, Fructus Schisandrae Chinensis 3-6 part, Cortex Eucommiae 5-10 part, Fructus Alpiniae Oxyphyllae 5-10 part and Fructus Leonuri 5-10 part.
6. the Chinese medicine for the treatment of uterine prolapse according to claim 1, it is characterized in that, be made up of the material medicine of following weight parts: Cortex Acanthopancis 11-15 part, Radix Codonopsis 21-30 part, Semen Lablab Album 16-20 part, Rhizoma Cimicifugae 8-10 part, Endoconcha Sepiae 11-15 part, Halloysitum Rubrum 11-15 part, Fructus Schisandrae Chinensis 7-10 part, Cortex Eucommiae 11-15 part, Fructus Alpiniae Oxyphyllae 11-15 part and Fructus Leonuri 11-15 part.
7. the Chinese medicine of claim 1 or the treatment uterine prolapse described in any one of 2-6, preparation method can make the one of decoction, powder, tablet, granule, pill, capsule routinely.
CN201510160005.5A 2015-04-07 2015-04-07 A kind of Chinese medicine for treating the prolapse of uterus Expired - Fee Related CN104771679B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102451338A (en) * 2010-10-27 2012-05-16 朱秀兰 Formula of Chinese medicine for treating uterine prolapse
CN103720814A (en) * 2012-10-14 2014-04-16 江月锋 Cimicifugae foetidae health wine for prolapse of uterus
CN103961647A (en) * 2014-05-14 2014-08-06 马鞍山科信咨询有限公司 Chinese medicinal preparation for treating uterine prolapse

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102451338A (en) * 2010-10-27 2012-05-16 朱秀兰 Formula of Chinese medicine for treating uterine prolapse
CN103720814A (en) * 2012-10-14 2014-04-16 江月锋 Cimicifugae foetidae health wine for prolapse of uterus
CN103961647A (en) * 2014-05-14 2014-08-06 马鞍山科信咨询有限公司 Chinese medicinal preparation for treating uterine prolapse

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
夏桂成: "《夏桂成实用中医妇科学》", 31 October 2009 *
张兴儒: "《新编现代家庭实用偏方验方全书》", 29 February 2008 *

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