CN104771572B - Chinese medicine preparation for postpartum hemostasis and preparation method thereof - Google Patents
Chinese medicine preparation for postpartum hemostasis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine preparations for postpartum hemostasis, it is characterised in that：The primary raw material of following weight proportions is taken to be prepared：5 15 parts of cirsii japonici,radix, 8 17 parts of Sedum uizoon, 6 12 parts of scouring rush, 5 15 parts of Ageratum conyzoides, 6 10 parts of campanulaceae, 5 15 parts of dandelion, 10 14 parts of the coptis, 7 13 parts of schefflera arboricola, 8 14 parts of Radix Astragali, 39 parts of Radix Ophiopogonis, 4 11 parts of Poria cocos, 9 16 parts of goldenrod, 38 parts of amber, 8 15 parts of rhizoma dioscoreae nipponicae, 24 parts of cutworm, 68 parts of Dysosma versipellis, 57 parts of gerbera, 15 18 parts of honeysuckle.Chinese medicine preparation of the present invention is used for the principle of postpartum hemostasis based on traditional Chinese medicine.The medicinal material of selection has the effect of hemostasis and anti-inflammation, for postpartum hemostasis diagnosis and treatment based on an overall analysis of the illness and the patient's condition, belongs to the prescription treated both principal and secondary aspect of disease.Play the role of to postpartum hemostasis fabulous.
Description
Technical field
The invention discloses a kind of Chinese medicine preparation, in particular for Chinese medicine preparation of postpartum hemostasis and preparation method thereof.Belong to
Traditional Chinese medicine field.
Background technology
After delivery of baby 24 it is small when internal haemorrhage amount be known as postpartum haemorrhage more than 500mL person, 80% be happened at postpartum 2 it is small when it is interior.
After late puerperal hemorrhage refers to when childbirth 24 is small, the uterus occurred within puerperium is bled profusely, and is more common in postpartum 1~2 week.
Postpartum haemorrhage is the serious complication of term, is to cause one of four big reasons of maternal death.In China, postpartum haemorrhage is near
It is always first reason for causing maternal death over year, it is more prominent particularly this case that Far-away Backward Areas.Production
The incidence of bleeding accounts for the 2%~3% of childbirth sum afterwards, actual to fall ill since the subjective factor for measuring and collecting amount of bleeding is larger
Rate higher.
The cause of disease：The pathogenic factor of postpartum haemorrhage is followed successively by uterine contractions fatigue, soft birth canal lacerated wound, placenta factors and blood coagulation work(
It can obstacle.Four big reasons can merge presence, can also reciprocal causation.1. uterine inertia：It is the most common reason of postpartum haemorrhage,
Account for 70%.The anatomic distribution of uterus muscle fibre is inner ring, outer vertical, middle intertexture.Under normal circumstances, after delivery of baby, different directions are walked
Capable uterus muscle fibers contract plays effective contention effect to the blood vessel muscle bundle.It is powerless if there is uterus muscle fibers contract
I.e. uterine inertia then loses to effective contention effect of blood vessel and postpartum haemorrhage occurs.It is common because being known as：1. systemic factor：Production
Woman puts upon the full stretch when to giving a birth excessively frightened, especially vaginal delivery is lacked enough confidence can then cause uterine contraction uncoordinated or
Uterine inertia.Such situation may need draw using sedative and anesthetic etc. after just before giving birth that increase postpartum uterine contraction weak and draw
Play postpartum haemorrhage；2. obstetrical factors：Stages of labor is long cause puerpera extremely tired and cachexia or stages of labor it is too fast, can cause
Uterine contractions fatigue；Hydramnion, macrosomia and multifetation make uterus muscle fibre hyper-extended, postpartum muscle fibre contracting reactivation power
Difference repeatedly gives a birth and causes uterus muscle fibre damage, can cause uterine contractions fatigue.Preeclampsia（Severe）, severe anemia, palace
The obstetric complications such as chamber infection and complication make uterus muscle fiber oedema and cause uterine contractions fatigue；3. uterine factors：Uterus
Fibromuscular dysplasia, such as uterine malformation or fibroid.2. placenta factors：Account for 20% or so of reason of postpartum hemorrhage.According to
Separation of placenta situation, mazischesis, placenta accreta and part placenta and/or fetal membrane residual can influence uterine contraction, and postpartum is caused to go out
Blood.Mazischesis：Placenta 30 minutes not yet discharge persons after delivery of baby claim mazischesis.May with uterine contraction agent improper use or
Massage uterus etc. roughly, stimulates and generates tonic uterine contraction, and in uterus, upper and lower section intersection or cervical orifice form contractile ring, will
The placenta of stripping is embedding to be closed in causing mazischesis in uterine cavity；Uterine inertia or because filling of bladder oppress lower uterine segment, can also cause
Though placenta has been removed and has been stranded in uterine cavity.Cause postpartum haemorrhage if mazischesis interferes normal uterine contraction, and clot poly is in son
In uterine cavity, and then uterine cavity increase is caused to cause uterine inertia, vicious circle is formed if handling not in time and causes serious consequence；
The reason for placenta accreta occurs is mainly improper related with operation technique.Such as too early after delivery of baby or mistake heavy massage uterus, interference
The normal contraction in uterus and contracting are multiple, and placental debris is caused to remove, and release surface blood sinus is open and Massive Bleeding；It also can be due to previously more
Secondary dilatation and curettage or uteroventral operation make, and make endometrial impairment and easily cause placenta accreta or implantation.3. soft birth canal lacerated wound：Soft birth canal is split
Wound includes perineum, vagina and uterine neck and lower uterine segment lacerated wound.Common factors：Vulvar sample poor flexibility, vulva, colpitis change
Become；Precipitate labor, force of labor are too strong, macrosomia；Vagina surgical delivery；It is not careful that soft birth canal checks, omits blutpunkte.Suture, hemostasis are not
Thoroughly etc..4. coagulation disorders：Common cause has placental abruption, amniotic fluid embolism, stillborn foetus and Acute Fatty Liver During Pregnancy etc. to draw
The coagulation disorders risen, it is a small number of by primary hematologic disease such as thrombopenia, leukaemia, alpastic anemia or again
Syndrome virus hepatitis etc. causes.5. inversion of uterus：It is rare, mostly caused by third stage of labor is dealt with improperly, such as firmly compressing palace bottom or
Umbilical cord etc. is drawn with sudden force.
Postpartum haemorrhage is interior when mostly occurring that 2 is small after delivery of baby, can be happened at placenta give birth to before, it is afterwards or front and rear simultaneous
Have.Colporrhagia can be massive haemorrhage in a short time, also can be long lasting for a small amount of bleeding.It is generally dominant, but also have recessive bleeding
Person.
Clinical manifestation：Predominantly colporrhagia, haemorrhagic shock, secondary anemia, if excessive blood loss can concurrent dispersivity
Intravascular coagulation.It is different whether the weight of symptom regards blood loss, speed and merges anaemia.Massive haemorrhage in a short time can go out rapidly
Now suffer a shock.It should be noted that in shock early stage since the in vivo compensatory mechanism vital sign patient of machine such as pulse, blood pressure etc. may be
It in normal range (NR), but stills need tightly to monitor at this time, EARLY RECOGNITION is carried out to risk factors, assess amount of bleeding and carry out positive
Treatment.In clinic often in the presence of when lose blood to a certain extent occur decompensation performance such as pulse speed, blood pressure decline just cause again
Depending on so losing optimal treatment opportunity.In addition, such as puerpera's original has suffered from anaemia, even if bleeding is few, can also suffer a shock, and
It is not easy to correct.Therefore, comprehensively careful observation and analysis must be made to each puerpera, in order to avoid delay rescue opportunity.
The content of the invention
There is presently no the more ripe Chinese medicine preparations for postpartum hemostasis to be applied, it is an object of the present invention to
Chinese medicine preparation for postpartum hemostasis is provided, has the characteristics that easy to operate, evident in efficacy, and its use is relatively conventional in the localities
Chinese medicine as raw material, it is of low cost.
The above-mentioned purpose of the present invention is achieved through the following technical solutions：
For the Chinese medicine preparation of postpartum hemostasis, the primary raw material of following weight proportions is taken to be prepared：5-15 parts of cirsii japonici,radix,
8-17 parts of Sedum uizoon, 6-12 parts of scouring rush, 5-15 parts of Ageratum conyzoides, 6-10 parts of campanulaceae, 5-15 parts of dandelion, 10-14 parts of the coptis, seven leaves
7-13 parts of lotus, 8-14 parts of Radix Astragali, Radix Ophiopogonis 3-9 part, 4-11 parts of Poria cocos, 9-16 parts of goldenrod, 3-8 parts of amber, rhizoma dioscoreae nipponicae 8-15
Part, 2-4 parts of cutworm, 6-8 parts of Dysosma versipellis, 5-7 parts of gerbera, 15-18 parts of honeysuckle.
For postpartum hemostasis Chinese medicine preparation, more preferred scheme, take following weight proportions primary raw material prepare and
Into：8-13 parts of cirsii japonici,radix, 12-14 parts of Sedum uizoon, 8-10 parts of scouring rush, 8-13 parts of Ageratum conyzoides, 7-9 parts of campanulaceae, 8-13 parts of dandelion,
11-13 parts of the coptis, 9-11 parts of schefflera arboricola, 10-12 parts of Radix Astragali, Radix Ophiopogonis 5-7 part, 6-9 parts of Poria cocos, 11-15 parts of goldenrod, amber
4-7 parts, 10-13 parts of rhizoma dioscoreae nipponicae, 2.5-3.5 parts of cutworm, 6.5-7.5 parts of Dysosma versipellis, 5.5-6.5 parts of gerbera, honeysuckle 16-17
Part.
For the Chinese medicine preparation of postpartum hemostasis, optimal scheme takes the primary raw material of following weight proportions to be prepared：Greatly
11 parts of Ji root, 13 parts of Sedum uizoon, 9 parts of scouring rush, 12 parts of Ageratum conyzoides, 8 parts of campanulaceae, 11.5 parts of dandelion, 12 parts of the coptis, schefflera arboricola 10
Part, 11 parts of Radix Astragali, 6 parts of Radix Ophiopogonis, 7.5 parts of Poria cocos, 13 parts of goldenrod, 5 parts of amber, 11.5 parts of rhizoma dioscoreae nipponicae, 3 parts of cutworm, illiciumverum
7 parts of lotus, 6 parts of gerbera, 16.5 parts of honeysuckle.
The preparation process of above-mentioned Chinese medicine preparation is as follows：
It 1. cutworm is taken to clean, drains away the water, takes the edible oil of 1-3 times of cutworm weight, be put into the hot pot dryouied, treat in pot
Surrounding puts into cutworm when playing cigarette, and it is for use to be ground into smalls for frying 3-7 minutes；
It 2. cirsii japonici,radix, Sedum uizoon and campanulaceae are cut into silk, is placed in preheated container, with being fried with slow fire surface buff
And thorn is burnt, is taken out when internal light yellow and dries in the air cool to room temperature, is ground into fine powder, it is for use to cross 80-120 mesh sieves；
3. scouring rush, Ageratum conyzoides, dandelion and the coptis are cleaned, stripping and slicing yellow rice wine sprays even, and when slightly stewing 5-15 is small, taking-up drains
Yellow rice wine, be placed in it is micro- in pot fry to crisp, it is for use to be ground into smalls while hot；
4. by schefflera arboricola, Radix Astragali, Radix Ophiopogonis, Poria cocos, goldenrod, amber, rhizoma dioscoreae nipponicae, Dysosma versipellis, gerbera and honeysuckle
It is placed in marmite, adds water to cook to boiling, turn to be cooked by slow fire 20-40 minutes, close the lid, decocting 5-15 minutes, filtering, filter
Liquid is spare, and filter residue is exposed to the sun 4-8 days in the sunlight, and small fire is dried 10-20 minutes slowly on iron plate is placed in, and it is for use to be ground into smalls；
5. by step, 4. gained filtrate is slowly heated, when filtrate is concentrated into the 1/2 of original volume, input step 1. -4. institute
Smalls is obtained, is sufficiently stirred into thick paste；By thick paste dry 1-2 it is small when, obtain drying object, in temperature to be dry at 60-80 DEG C, pack is
Into.
1. the preparation method of above-mentioned Chinese medicine preparation, step take the edible oil of 1.5-2.5 times of cutworm weight（Preferably, take ground
The edible oil that 2 times of silkworm weight）.
The preparation method of above-mentioned Chinese medicine preparation, 2. fine powder crosses 90-110 mesh sieves to step（Preferably, fine powder crosses 100 mesh sieves）.
The preparation method of above-mentioned Chinese medicine preparation, for step when 3. slightly stewing 8-13 is small, taking-up drains yellow rice wine（Preferably, slightly stewing 10
Hour, taking-up drains yellow rice wine）.
4. the preparation method of above-mentioned Chinese medicine preparation, step are added water to cook to boiling, turn to be cooked by slow fire 25-35 minutes（It is preferred that
, it adds water to cook to boiling, turns to be cooked by slow fire 30 minutes）.
The preparation method of above-mentioned Chinese medicine preparation, 4. filter residue is exposed to the sun 5-7 days step in the sunlight, and small fire is slow on iron plate is placed in
It dries 13-18 minutes（Preferably, filter residue is exposed to the sun 6 days in the sunlight, and small fire is dried 15 minutes slowly on iron plate is placed in）.
The preparation method of above-mentioned Chinese medicine preparation, step 5. by thick paste dry 1.3-1.8 it is small when, obtain drying object, be in temperature
It is dry at 65-75 DEG C（Preferably, by thick paste dry 1.5 it is small when, obtain drying object, be dry at 70 DEG C in temperature）.
Application method：For Chinese medicine preparation of the present invention is made to reach optimum therapeuticing effect, for several times daily, 5-10g is taken, be placed on bleeding
Position.
The pharmacological effect of each bulk pharmaceutical chemicals is respectively：
Cirsii japonici,radix：Alias horse Ji, brave Ji, cat Ji, field thistle, Herba seu Radix Cirsii Japonici (Radix Saussureae cordifoliae), field thistle dish etc..Flavor efficacy is sweet, bitter, and property is cooler
Profit.Work(arrogates to oneself cool blood, hemostasis, suitable for a variety of haemorrhages caused by treatment blood-heat bleeding, such as spitting of blood, bleeding from five sense organs or subcutaneous tissue, uterine bleeding, hematuria；
It is longer than stagnation resolvation, subduing inflammation, myogenic apocenosis again.Available for treatment intestines wind acute appendicitis, pain ulcer pyogenic infections, furunculosis, scrofula tuberculosis etc..
Sedum uizoon：Base：For the root or herb of composite family gynura segetum platymiscium chrysanthemum leaf Radix Notoginseng.Ingredient：Root contains alkaloid：A thousand li
The peaceful alkali of light, senlciphylline, sineciphyllinine, seneciphyllinine etc..Aerial part contains PEARLITOL 25C, succinic acid, 5- methyl
Urea pyrimidine, adenine, ammonium chloride, chrysanthemum Radix Notoginseng bases, rutin sophorin.Pharmacological property：Sweet, slight bitter, temperature.Function cures mainly：Blood-breaking is subsided a swelling, only
Blood, analgesic.Treating swelling and pain by traumatic injury, traumatic hemorrhage are cured mainly, extravasated blood is spitted blood, bleeding from five sense organs or subcutaneous tissue, and spitting of blood is had blood in stool, uterine bleeding, dysmenorrhoea, postpartum stasis abdominal pain,
Rheumatalgia, sore carbuncle subcutaneous ulcer malignant boil, worm snake bite.
Scouring rush：Base：For the herb of Equisetaceae horse-tail scouring rush.Ingredient：Aerial part contains volatile oil, wherein fat
Acid：Succinic acid, fumaric acid, glutaric acid methyl esters, P-hydroxybenzoic acid, m-hydroxybenzoic acid, forulic acid, vanillic acid, caffeic acid
Deng.Pharmacological property：Sweet, slight bitter is put down.Return lung, liver, gallbladder channel.Function cures mainly：Wind-dispelling heat-dissipating, removing nebula, hemostasis.Wind-heat hot eyes is cured mainly,
Mesh gives birth to cloudiness, and tearing against wind, discharging fresh blood stool, hemorrhoid blood, bloody flux, married woman is mensostaxis, rectal prolapse.
Ageratum conyzoides：Base：For the herb of composite family Ageratum plant Ageratum conyzoides.Ingredient：Herb contains flavonoids：Ageratum conyzoides is yellow
Ketone A, B, C, Nobiletin, senensetin, lindera brass B, etc..Alkaloid：Lycopod amine, echinatine.Triterpene compound：Nothing
Bridle terpene.Sterols：Stigmasterol etc..Volatile oil：Ageratum conyzoides chromene, cumarin etc..Aerial part contains chromene class：7- methoxyl groups-
2,2- dimethyl chromogen alkene, 7,8- dimethoxys -2 etc..Pharmacological property：It is slight bitter, pungent, it is cool.Function cures mainly：It is clearing heat and detoxicating, stop blooding, only
Bitterly.Cold, fever, abscess of throat are cured mainly, aphthae is spat blood, bleeding from five sense organs or subcutaneous tissue, uterine bleeding, epigastric pain, arthralgia pain due to rheumatism, traumatic injury,
Traumatic hemorrhage, thrush, carbuncle swells furunculosis, eczema itch.
Campanulaceae：Facilitaing lung, relieving sore-throat, eliminating the phlegm, apocenosis.For coughing with a lot of sputum, chest distress, pharyngalgia, hoarse voice, lung carbuncle pyemesis, sore
Ulcer purulence is not into bursting.
Dandelion：Contain a variety of health such as taraxol, taraxacin, choline, organic acid, synanthrin in dandelion plant
Nutritional ingredient.Nature and flavor are sweet, slight bitter, tremble with fear.Return liver, stomach.There are diuresis, laxative, removing jaundice subcutaneous ulcer, cholagogic and other effects.Control heat toxin, carbuncle swells,
Sore, internal carbuncle, red eye, swell pain, damp and hot, jaundice, the puckery pain of dribbling urination, furuncle swelling toxin, acute mastitis, scrofula, toothache, hot eyes, pharyngalgia,
Lung carbuncle, acute appendicitis, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.Control acute mastitis, adenolymphitis, scrofula, boil poisonous soreness, acute conjunctivitis, sense
Emit fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infections etc..Dandelion is raw-eaten, fries
It eats, cook soup, be the plant of dietotherapeutic.
The coptis：Nature and flavor bitter, it is cold in nature.The channel tropism thoughts of returning home, spleen, stomach, liver, courage, large intestine channel.Effect heat-clearing and damp-drying drug, purging intense heat and detonicating.
It cures mainly damp and hot feeling of fullness, vomits acid regurgitation, rush down dysentery, jaundice, unconsciousness due to high fever, heart-fire hyperactivity, dysphoria and insomnia, palpitation and uneasiness, blood-head tells nosebleed,
Hot eyes, toothache, quenches one's thirst, and carbuncle swells treat sore；Eczema, wet sore are controlled outside, duct is suppurated.
Schefflera arboricola：Base：For the root or cauline leaf of Araliaceae Schefflera plant schefflera arboricola.Ingredient：Contain sickleleaf in schefflera arboricola
Celery alcohol；Also contain（E）--farnesene, poriferasterol.Contain 2 Triterpene saponins in leaf and stem：3-O- [a-L- rhamnopyranoses
Base-（la）--D- glucopyranosiduronic acids base] oleanolic acid 28-O--D- glucopyranosides, 3-O- [a-L- pyrans I
Primary glycosyl-（la）--D- glucopyranosiduronic acids base] oleanolic acid 28-O--D- glucopyranosides.There is cell to swash in leaf
Peptide element class, trans- maize purine, benzyladenine.Pharmacological property：Pungent, sweet, slight bitter, temperature.Function cures mainly：Wind-expelling pain-stopping, promoting blood circulation disappear
It is swollen.Arthralgia pain due to rheumatism is cured mainly, is had a headache, toothache, epigastric pain, dysmenorrhoea, postpartum abdominal pain, treating swelling and pain by traumatic injury, fracture, sore swells.
Radix Astragali：Nature and flavor：It is sweet, tepor.Channel tropism：Return lung, spleen, liver and kidney channel.It has enhancing body's immunity, liver protection, profit
Urine, anti-aging, resisting stress, decompression and wide antibacterial action.
Radix Ophiopogonis：Sweet, slight bitter is slightly cold.The thoughts of returning home, lung, stomach.Nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire.For dryness of the lung dry cough, deficiency of Yin consumptive disease
It coughs, larynx numbness pharyngalgia, injury thirst, Heat Diabetes, vexed insomnia, dry constipation of intestines.
Poria cocos：Nature and flavor are sweet in flavor, light, mild-natured.The channel tropism thoughts of returning home, lung, spleen, kidney channel.Effect clearing damp and promoting diuresis, invigorating the spleen, calming heart.It is main
It controls for oedema oliguria, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear.
Goldenrod：Base：For the herb or root of composite family goldenrod platymiscium goldenrod.Ingredient：Aerial part contains
Saponin component：Goldenrod glycosides, activities of Solidago virgaurea L saponin(e 3 are 3, Solidago saponin(e, Solidago Canadensis saponin(e,
Huge goldenrod saponin(e, triterpene glycosides of polygalic acid etc..Pharmacological property：It is pungent, bitter, it is cool.Function cures mainly：Wind and heat dispersing, removing toxicity for detumescence.It is main
Control anemopyretic cold, abscess of throat, cough with lung heat, jaundice, heat gonorrhea, carbuncle swells boil, venomous snake bite, traumatic injury.
Amber：Base：For the resin of ancient times Pinaceae pine genus plant, underground is imbedded in through the older fossil sample object being transformed
Matter.Ingredient：Main resinous, volatile oil, diabietionlic acid, succinosilvic acid, amber tree resin acid, succinoabietol, succinic acid,
Borneol etc..Pharmacological property：Sweet and neutral.The thoughts of returning home, liver, bladder warp.Function cures mainly：Tranquillizing the mind by relieving convulsion, dissipate stasis of blood hemostasis, promoting diuresis for stranguria, screen of dispelling are bright
Mesh.Insomnia is cured mainly, is palpitated with fear, infantile convulsion, epilepsy, extravasated blood amenorrhoea, postpartum abdominal pain , lumps in the chest and abdomen, blood strangury blood urine, mesh life ocular.
Rhizoma dioscoreae nipponicae：Alias earthworm, dragon of ploughing wear keel, ground joist, Buddha's warrior attendant bone, chicken bone, mountain Changshan, Changshan, climb the mountain
Tiger, tip of a whip dish.Flavor efficacy is bitter, puts down.Return liver, lung channel.Function is activated blood and relaxed tendons, timid wind analgesic, relieving cough and asthma, timid phlegm.It is suitable for
Lumbocrural pain, muscles and bones numbness, traumatic injury, acute waist sprain, cough are panted.
Cutworm：Alias soil cordyceps, white cordyceps, white cordyceps sinensis, tuberculosis grass.Flavor efficacy sweet and neutral.Function kidney-nourishing moistens
Lung, nourishing yin and supplementing blood, clearing heat and relieving fidgetness.Suitable for pulmonary tuberculosis cough, deficiency syndrome of the lung asthma, haematemesis, night sweat, anaemia, infantile malnutrition.
Dysosma versipellis：Base：For the root and rhizome of Berberidaceae Dysosma plant Dysosma versipellis, Dysosma Pleiantha and dysosma veitchii Fu.Into
Point：1. Dysosma versipellis rhizome contains lignanoid：Podophyllotoxin, picropodophyllin；Flavonoids：Diphyllin Kaempferol, Quercetin etc..2.
Dysosma Pleiantha rhizome contains lignanoid：Podophyllotoxin, dehydropodophyllotoxin, podophyllotoxone etc..3. dysosma veitchii Fu root Podophyllum emodi var chinense containing deoxidation
Toxin,-peltain, podophyllotoxin, Kaempferol -3--D-Glucose glycosides, glucose, sucrose and-sitosterol.Pharmacological property：
It is bitter, acrid in flavour and warm in nature.It is toxic.Return lung, Liver Channel.Function cures mainly：Resolving sputum is detoxified, eliminating stasis and resolving masses.Cure mainly cough, abscess of throat, scrofula, goitre
Knurl, nameless gall, herpes zoster, venomous snake bite, traumatic injury, arthralgia pain due to rheumatism.
Gerbera：Also known as careless, the small fire weed of gold, shank grass are burnt, it is the herb of composite family Gerbera plant gerbera.Pharmacological property：This
Product are crispaturaed agglomerating, and in withered green, rhizome is short, lower raw most thin fibrous roots, achene spindle, and both ends are shunk, and gas is micro-, bitter, cold in nature.
Ingredient：Aerial part contains coumarin kind compound, and containing prunasin, big fourth glycosides.It is found according to modern pharmacological research, which has
The effect of antibacterial, clearing heat and promoting diuresis, removing toxicity for detumescence, for cough with lung heat, damp-heat dysentery, heat gonorrhea, rheumatic arthritis etc..
Honeysuckle：Its effect is mainly clearing heat and detoxicating, cures mainly warm disease heating, toxic-heat and blood stasis, ulcer serious case of furuncle etc..Modern study
It proves, honeysuckle contains the pharmacological components such as chlorogenic acid, cyanidenon glycosides, to hemolytic streptococcus, Staphylococcus aureus etc.
Various pathogens and infection of the upper respiratory tract Causative virus etc. have stronger restraint, in addition can also strengthen immunity, Robust speaker feature, shield
Liver, antitumor, anti-inflammatory, antipyretic, hemostasis（Blood coagulation）, inhibit intestinal absorption cholesterol etc., clinical application is very extensive, can be with it
Its compatibility of drugs plants illness for treating respiratory tract infection, bacillary dysentery, acute urinary, hypertension etc. more than 40.Honeysuckle
It is cold in nature, it is sweet in flavor, enter lung, the heart, stomach, have effects that clearing heat and detoxicating, anti-inflammatory, qi-restoratives treats wind, cure mainly disease under turgor, warm disease hair
The diseases such as heat, heat toxin large carbuncle and tumour.It is for dizziness, thirst, sweating and boring, enteritis, bacillary dysentery, measles, pneumonia, second
Brain, epidemic meningitis, acute mastitis, septicemia, appendicitis, skin infection, ulcer boils, erysipelas, parotitis, suppurative tonsillitis
Etc. illnesss have certain curative effect.
Chinese medicine preparation of the present invention is used for the principle of postpartum hemostasis based on traditional Chinese medicine.The medicinal material of selection has hemostasis and anti-inflammation
Effect for postpartum hemostasis diagnosis and treatment based on an overall analysis of the illness and the patient's condition, belongs to the prescription treated both principal and secondary aspect of disease.Play the role of to postpartum hemostasis fabulous.
Specific embodiment
With reference to embodiment and the experimental example technical solution that the present invention will be described in detail, but protection domain is not limited by this.
Embodiment 1：For the Chinese medicine preparation of postpartum hemostasis, the primary raw material of following weight proportions is taken to be prepared（Every part
Take 10g）：5 parts of cirsii japonici,radix, 8 parts of Sedum uizoon, 6 parts of scouring rush, 5 parts of Ageratum conyzoides, 6 parts of campanulaceae, 5 parts of dandelion, 10 parts of the coptis, seven leaves
7 parts of lotus, 8 parts of Radix Astragali, 3 parts of Radix Ophiopogonis, 4 parts of Poria cocos, 9 parts of goldenrod, 3 parts of amber, 8 parts of rhizoma dioscoreae nipponicae, 2 parts of cutworm, Dysosma versipellis 6
Part, 5 parts of gerbera, 15 parts of honeysuckle.
The preparation method of the above-mentioned Chinese medicine preparation for postpartum hemostasis, step are as follows：
It 1. cutworm is taken to clean, drains away the water, takes the edible oil of 1 times of cutworm weight, be put into the hot pot dryouied, treat four in pot
Cutworm is put into during Zhou Qiyan, it is for use to be ground into smalls for frying 3 minutes；
It 2. cirsii japonici,radix, Sedum uizoon and campanulaceae are cut into silk, is placed in preheated container, with being fried with slow fire surface buff
And thorn is burnt, is taken out when internal light yellow and dries in the air cool to room temperature, is ground into fine powder, it is for use to cross 80 mesh sieves；
3. scouring rush, Ageratum conyzoides, dandelion and the coptis are cleaned, stripping and slicing yellow rice wine spray it is even, it is slightly stewing 5 it is small when, taking-up drains Huang
Wine, be placed in it is micro- in pot fry to crisp, it is for use to be ground into smalls while hot；
4. by schefflera arboricola, Radix Astragali, Radix Ophiopogonis, Poria cocos, goldenrod, amber, rhizoma dioscoreae nipponicae, Dysosma versipellis, gerbera and honeysuckle
It is placed in marmite, adds water to cook to boiling, turn to be cooked by slow fire 20 minutes, close the lid, decocting 5 minutes, filtering, filtrate is standby
With filter residue is exposed to the sun 4 days in the sunlight, and small fire is dried 10- minutes slowly on iron plate is placed in, and it is for use to be ground into smalls；
5. by step, 4. gained filtrate is slowly heated, when filtrate is concentrated into the 1/2 of original volume, input step 1. -4. institute
Smalls is obtained, is sufficiently stirred into thick paste；By thick paste dry 1 it is small when, obtain drying object, in temperature to be dry at 60 DEG C, pack.
Embodiment 2：For the Chinese medicine preparation of postpartum hemostasis, the primary raw material of following weight proportions is taken to be prepared（Every part
Take 10g）：15 parts of cirsii japonici,radix, 17 parts of Sedum uizoon, 12 parts of scouring rush, 15 parts of Ageratum conyzoides, 10 parts of campanulaceae, 15 parts of dandelion, the coptis 14
Part, 13 parts of schefflera arboricola, 14 parts of Radix Astragali, 9 parts of Radix Ophiopogonis, 11 parts of Poria cocos, 16 parts of goldenrod, 8 parts of amber, 15 parts of rhizoma dioscoreae nipponicae, cutworm 4
Part, 8 parts of Dysosma versipellis, 7 parts of gerbera, 18 parts of honeysuckle.
The preparation method of the above-mentioned Chinese medicine preparation for postpartum hemostasis, step are as follows：
It 1. cutworm is taken to clean, drains away the water, takes the edible oil of 3 times of cutworm weight, be put into the hot pot dryouied, treat four in pot
Cutworm is put into during Zhou Qiyan, it is for use to be ground into smalls for frying 7 minutes；
It 2. cirsii japonici,radix, Sedum uizoon and campanulaceae are cut into silk, is placed in preheated container, with being fried with slow fire surface buff
And thorn is burnt, is taken out when internal light yellow and dries in the air cool to room temperature, is ground into fine powder, it is for use to cross 120 mesh sieves；
3. scouring rush, Ageratum conyzoides, dandelion and the coptis are cleaned, stripping and slicing yellow rice wine spray it is even, it is slightly stewing 15 it is small when, taking-up drains Huang
Wine, be placed in it is micro- in pot fry to crisp, it is for use to be ground into smalls while hot；
4. by schefflera arboricola, Radix Astragali, Radix Ophiopogonis, Poria cocos, goldenrod, amber, rhizoma dioscoreae nipponicae, Dysosma versipellis, gerbera and honeysuckle
It is placed in marmite, adds water to cook to boiling, turn to be cooked by slow fire 40 minutes, close the lid, decocting 15 minutes, filtering, filtrate is standby
With filter residue is exposed to the sun 8 days in the sunlight, and small fire is dried 20 minutes slowly on iron plate is placed in, and it is for use to be ground into smalls；
5. by step, 4. gained filtrate is slowly heated, when filtrate is concentrated into the 1/2 of original volume, input step 1. -4. institute
Smalls is obtained, is sufficiently stirred into thick paste；By thick paste dry 2 it is small when, obtain drying object, in temperature to be dry at 80 DEG C, pack.
Embodiment：3 are used for the Chinese medicine preparation of postpartum hemostasis, and the primary raw material of following weight proportions is taken to be prepared（Every part
Take 10g）：8 parts of cirsii japonici,radix, 12 parts of Sedum uizoon, 8 parts of scouring rush, 8 parts of Ageratum conyzoides, 7 parts of campanulaceae, 8 parts of dandelion, 11 parts of the coptis, seven leaves
9 parts of lotus, 10 parts of Radix Astragali, 5 parts of Radix Ophiopogonis, 6 parts of Poria cocos, 11 parts of goldenrod, 4 parts of amber, 10 parts of rhizoma dioscoreae nipponicae, 2.5 parts of cutworm are octagonal
6.5 parts of lotus, 5.5 parts of gerbera, 16 parts of honeysuckle.
The preparation method of the above-mentioned Chinese medicine preparation for postpartum hemostasis, step are as follows：
It 1. cutworm is taken to clean, drains away the water, takes the edible oil of 1.5 times of cutworm weight, be put into the hot pot dryouied, treat in pot
Surrounding puts into cutworm when playing cigarette, and it is for use to be ground into smalls for frying 4 minutes；
It 2. cirsii japonici,radix, Sedum uizoon and campanulaceae are cut into silk, is placed in preheated container, with being fried with slow fire surface buff
And thorn is burnt, is taken out when internal light yellow and dries in the air cool to room temperature, is ground into fine powder, it is for use to cross 90 mesh sieves；
3. scouring rush, Ageratum conyzoides, dandelion and the coptis are cleaned, stripping and slicing yellow rice wine spray it is even, it is slightly stewing 8 it is small when, taking-up drains Huang
Wine, be placed in it is micro- in pot fry to crisp, it is for use to be ground into smalls while hot；
4. by schefflera arboricola, Radix Astragali, Radix Ophiopogonis, Poria cocos, goldenrod, amber, rhizoma dioscoreae nipponicae, Dysosma versipellis, gerbera and honeysuckle
It is placed in marmite, adds water to cook to boiling, turn to be cooked by slow fire 25 minutes, close the lid, decocting 8 minutes, filtering, filtrate is standby
With filter residue is exposed to the sun 5 days in the sunlight, and small fire is dried 13 minutes slowly on iron plate is placed in, and it is for use to be ground into smalls；
5. by step, 4. gained filtrate is slowly heated, when filtrate is concentrated into the 1/2 of original volume, input step 1. -4. institute
Smalls is obtained, is sufficiently stirred into thick paste；By thick paste dry 1.3 it is small when, obtain drying object, in temperature to be dry at 65 DEG C, pack.
Embodiment 4：For the Chinese medicine preparation of postpartum hemostasis, the primary raw material of following weight proportions is taken to be prepared（Every part
Take 10g）：13 parts of cirsii japonici,radix, 14 parts of Sedum uizoon, 10 parts of scouring rush, 13 parts of Ageratum conyzoides, 9 parts of campanulaceae, 13 parts of dandelion, 13 parts of the coptis,
11 parts of schefflera arboricola, 12 parts of Radix Astragali, 7 parts of Radix Ophiopogonis, 9 parts of Poria cocos, 15 parts of goldenrod, 7 parts of amber, 13 parts of rhizoma dioscoreae nipponicae, cutworm 3.5
Part, 7.5 parts of Dysosma versipellis, 6.5 parts of gerbera, 17 parts of honeysuckle.
The preparation method of the above-mentioned Chinese medicine preparation for postpartum hemostasis, step are as follows：
It 1. cutworm is taken to clean, drains away the water, takes the edible oil of 2.5 times of cutworm weight, be put into the hot pot dryouied, treat in pot
Surrounding puts into cutworm when playing cigarette, and it is for use to be ground into smalls for frying 6 minutes；
It 2. cirsii japonici,radix, Sedum uizoon and campanulaceae are cut into silk, is placed in preheated container, with being fried with slow fire surface buff
And thorn is burnt, is taken out when internal light yellow and dries in the air cool to room temperature, is ground into fine powder, it is for use to cross 110 mesh sieves；
3. scouring rush, Ageratum conyzoides, dandelion and the coptis are cleaned, stripping and slicing yellow rice wine spray it is even, it is slightly stewing 13 it is small when, taking-up drains Huang
Wine, be placed in it is micro- in pot fry to crisp, it is for use to be ground into smalls while hot；
4. by schefflera arboricola, Radix Astragali, Radix Ophiopogonis, Poria cocos, goldenrod, amber, rhizoma dioscoreae nipponicae, Dysosma versipellis, gerbera and honeysuckle
It is placed in marmite, adds water to cook to boiling, turn to be cooked by slow fire 35 minutes, close the lid, decocting 13 minutes, filtering, filtrate is standby
With filter residue is exposed to the sun 7 days in the sunlight, and small fire is dried 18 minutes slowly on iron plate is placed in, and it is for use to be ground into smalls；
5. by step, 4. gained filtrate is slowly heated, when filtrate is concentrated into the 1/2 of original volume, input step 1. -4. institute
Smalls is obtained, is sufficiently stirred into thick paste；By thick paste dry 1.8 it is small when, obtain drying object, in temperature to be dry at 75 DEG C, pack.
Embodiment 5：For the Chinese medicine preparation of postpartum hemostasis, the primary raw material of following weight proportions is taken to be prepared（Every part
Take 10g）：11 parts of cirsii japonici,radix, 13 parts of Sedum uizoon, 9 parts of scouring rush, 12 parts of Ageratum conyzoides, 8 parts of campanulaceae, 11.5 parts of dandelion, the coptis 12
Part, 10 parts of schefflera arboricola, 11 parts of Radix Astragali, 6 parts of Radix Ophiopogonis, 7.5 parts of Poria cocos, 13 parts of goldenrod, 5 parts of amber, 11.5 parts of rhizoma dioscoreae nipponicae, ground
3 parts of silkworm, 7 parts of Dysosma versipellis, 6 parts of gerbera, 16.5 parts of honeysuckle.
The preparation method of the above-mentioned Chinese medicine preparation for postpartum hemostasis, step are as follows：
It 1. cutworm is taken to clean, drains away the water, takes the edible oil of 2 times of cutworm weight, be put into the hot pot dryouied, treat four in pot
Cutworm is put into during Zhou Qiyan, it is for use to be ground into smalls for frying 5 minutes；
It 2. cirsii japonici,radix, Sedum uizoon and campanulaceae are cut into silk, is placed in preheated container, with being fried with slow fire surface buff
And thorn is burnt, is taken out when internal light yellow and dries in the air cool to room temperature, is ground into fine powder, it is for use to cross 100 mesh sieves；
3. scouring rush, Ageratum conyzoides, dandelion and the coptis are cleaned, stripping and slicing yellow rice wine spray it is even, it is slightly stewing 10 it is small when, taking-up drains Huang
Wine, be placed in it is micro- in pot fry to crisp, it is for use to be ground into smalls while hot；
4. by schefflera arboricola, Radix Astragali, Radix Ophiopogonis, Poria cocos, goldenrod, amber, rhizoma dioscoreae nipponicae, Dysosma versipellis, gerbera and honeysuckle
It is placed in marmite, adds water to cook to boiling, turn to be cooked by slow fire 30 minutes, close the lid, decocting 10 minutes, filtering, filtrate is standby
With filter residue is exposed to the sun 6 days in the sunlight, and small fire is dried 15 minutes slowly on iron plate is placed in, and it is for use to be ground into smalls；
5. by step, 4. gained filtrate is slowly heated, when filtrate is concentrated into the 1/2 of original volume, input step 1. -4. institute
Smalls is obtained, is sufficiently stirred into thick paste；By thick paste dry 1.5 it is small when, obtain drying object, in temperature to be dry at 70 DEG C, pack.
Experimental example one：In order to verify Chinese medicine composition of the present invention（Embodiment 5）Effect, we have extracted 400 patients
The experiment of drug has been carried out, has been divided into experimental group and control group, experimental group takes 5 gained Chinese medicine preparation of embodiment, and control group is taken
Other Chinese medicines and Western medicine drug for postpartum hemostasis.Inclusion criteria：Through being diagnosed as postpartum hemostasis patient, there is postpartum hemostasis clinic
Symptom is one or more.Curative effect situation criterion：1st, cure.After drug administration, malaise symptoms completely disappear；2nd, effectively.Clothes
After drug, malaise symptoms mitigate or partial disappearance；3rd, it is invalid.After drug administration, malaise symptoms are unchanged.
Table 1：Two groups of Clinical efficacy comparisons【Example】Table 1
Table 1
Chinese medicine preparation of the present invention cure rate compared with other drugs to stop blooding for postpartum is high, total effective rate 99%, effect
Control group is substantially better than, the Chinese medicine preparation of the invention is cheap, and ordinary people long-time service will not increase body and money
On burden.Do not occur an example side effect profile in clinical trial, security is much higher than with the similar Chinese and Western medicine to stop blooding in postpartum
Object, and quick, it is no longer that can ask and unavailable to make the healing that postpartum stops blooding, and is stopped blooding ideal peace currently used for postpartum
Full Chinese medicine preparation.
Claims (10)
1. for the Chinese medicine preparation of postpartum hemostasis, it is characterised in that：The raw material of following weight proportions is taken to be prepared：Cirsii japonici,radix 5-
15 parts, 8-17 parts of Sedum uizoon, 6-12 parts of scouring rush, 5-15 parts of Ageratum conyzoides, 6-10 parts of campanulaceae, 5-15 parts of dandelion, coptis 10-14
Part, 7-13 parts of schefflera arboricola, 8-14 parts of Radix Astragali, Radix Ophiopogonis 3-9 part, 4-11 parts of Poria cocos, 9-16 parts of goldenrod, 3-8 parts of amber wear mountain
It is 8-15 parts imperial, 2-4 parts of cutworm, 6-8 parts of Dysosma versipellis, 5-7 parts of gerbera, 15-18 parts of honeysuckle.
2. the Chinese medicine preparation according to claim 1 for postpartum hemostasis, it is characterised in that：Take the original of following weight proportions
Material is prepared：8-13 parts of cirsii japonici,radix, 12-14 parts of Sedum uizoon, 8-10 parts of scouring rush, 8-13 parts of Ageratum conyzoides, 7-9 parts of campanulaceae, Pu Gong
8-13 parts of English, 11-13 parts of the coptis, 9-11 parts of schefflera arboricola, 10-12 parts of Radix Astragali, Radix Ophiopogonis 5-7 part, 6-9 parts of Poria cocos, goldenrod 11-
15 parts, 4-7 parts of amber, 10-13 parts of rhizoma dioscoreae nipponicae, 2.5-3.5 parts of cutworm, 6.5-7.5 parts of Dysosma versipellis, 5.5-6.5 parts of gerbera, gold
16-17 parts of honeysuckle flower.
3. the Chinese medicine preparation according to claim 1 for postpartum hemostasis, it is characterised in that：Take following weight proportions
Raw material is prepared：11 parts of cirsii japonici,radix, 13 parts of Sedum uizoon, 9 parts of scouring rush, 12 parts of Ageratum conyzoides, 8 parts of campanulaceae, 11.5 parts of dandelion are yellow
Even 12 parts, 10 parts of schefflera arboricola, 11 parts of Radix Astragali, 6 parts of Radix Ophiopogonis, 7.5 parts of Poria cocos, 13 parts of goldenrod, 5 parts of amber, rhizoma dioscoreae nipponicae 11.5
Part, 3 parts of cutworm, 7 parts of Dysosma versipellis, 6 parts of gerbera, 16.5 parts of honeysuckle.
4. according to claim 1-3 any one of them for the preparation method of the Chinese medicine preparation of postpartum hemostasis, it is characterised in that：
Step is as follows：
It 1. cutworm is taken to clean, drains away the water, takes the edible oil of 1.5-2.5 times of cutworm weight, be put into the hot pot dryouied, treat in pot
Surrounding puts into cutworm when playing cigarette, and it is for use to be ground into smalls for frying 3-7 minutes；
It 2. cirsii japonici,radix, Sedum uizoon and campanulaceae are cut into silk, is placed in preheated container, with being fried with slow fire surface buff and thorn
Coke takes out when internal light yellow and dries in the air cool to room temperature, is ground into fine powder, it is for use to cross 90-110 mesh sieves；
3. scouring rush, Ageratum conyzoides, dandelion and the coptis are cleaned, stripping and slicing yellow rice wine sprays even, and when slightly stewing 8-13 is small, taking-up drains Huang
Wine, be placed in it is micro- in pot fry to crisp, it is for use to be ground into smalls while hot；
4. schefflera arboricola, Radix Astragali, Radix Ophiopogonis, Poria cocos, goldenrod, amber, rhizoma dioscoreae nipponicae, Dysosma versipellis, gerbera and honeysuckle are placed in
It in marmite, adds water to cook to boiling, turns to be cooked by slow fire 25-35 minutes, close the lid, decocting 5-15 minutes, filtering, filtrate is standby
With filter residue is exposed to the sun 5-7 days in the sunlight, and small fire is dried 13-18 minutes slowly on iron plate is placed in, and it is for use to be ground into smalls；
5. by step, 4. gained filtrate is slowly heated, when filtrate is concentrated into the 1/2 of original volume, input step 1. -4. gained it is thin
End is sufficiently stirred into thick paste；By thick paste dry 1.3-1.8 it is small when, obtain drying object, in temperature to be dry at 65-75 DEG C, pack is
Into.
5. the preparation method of Chinese medicine preparation according to claim 4, it is characterised in that：1. step takes 2 times of cutworm weight
Edible oil.
6. the preparation method of Chinese medicine preparation according to claim 4, it is characterised in that：2. fine powder crosses 100 mesh sieves to step.
7. the preparation method of Chinese medicine preparation according to claim 4, it is characterised in that：Step 3. slightly stewing 10 it is small when, take out
Drain yellow rice wine.
8. the preparation method of Chinese medicine preparation according to claim 4, it is characterised in that：4. step is added water to cook to boiling,
Turn to be cooked by slow fire 30 minutes.
9. the preparation method of Chinese medicine preparation according to claim 4, it is characterised in that：4. filter residue is exposed to the sun step in the sunlight
6 days, small fire was dried 15 minutes slowly on iron plate is placed in.
10. the preparation method of Chinese medicine preparation according to claim 4, it is characterised in that：5. thick paste is dried 1.5 by step small
When, drying object is obtained, it is dry in the case where temperature is 70 DEG C.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103223155A (en) * | 2013-05-20 | 2013-07-31 | 刘奎泉 | Medicament for treating postpartum hemorrhage |
| CN103285367A (en) * | 2013-07-03 | 2013-09-11 | 陈为兰 | Traditional Chinese medicine composition for bleeding after drug abortion |
| CN103751472A (en) * | 2014-01-26 | 2014-04-30 | 周晶 | Traditional Chinese medicine composition for treating postpartum hemorrhage |
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| CN103223155A (en) * | 2013-05-20 | 2013-07-31 | 刘奎泉 | Medicament for treating postpartum hemorrhage |
| CN103285367A (en) * | 2013-07-03 | 2013-09-11 | 陈为兰 | Traditional Chinese medicine composition for bleeding after drug abortion |
| CN103751472A (en) * | 2014-01-26 | 2014-04-30 | 周晶 | Traditional Chinese medicine composition for treating postpartum hemorrhage |
Non-Patent Citations (1)
| Title |
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| 产后出血的辩证和治疗;祝恒琛等;《中医杂志》;19840530;第10卷(第5期);第19-21页 * |
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