CN104736518B - 制备噻二唑的方法 - Google Patents
制备噻二唑的方法 Download PDFInfo
- Publication number
- CN104736518B CN104736518B CN201380026364.0A CN201380026364A CN104736518B CN 104736518 B CN104736518 B CN 104736518B CN 201380026364 A CN201380026364 A CN 201380026364A CN 104736518 B CN104736518 B CN 104736518B
- Authority
- CN
- China
- Prior art keywords
- alkyl
- substituted
- naphthyl
- group
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 *C(*)(OC1)O[C@]1C=NO Chemical compound *C(*)(OC1)O[C@]1C=NO 0.000 description 2
- BHLLWQZPLICABU-LLVKDONJSA-N CC(C)(OC1)O[C@H]1C(/N=C(\S)/Sc1ccc(C)cc1)=N Chemical compound CC(C)(OC1)O[C@H]1C(/N=C(\S)/Sc1ccc(C)cc1)=N BHLLWQZPLICABU-LLVKDONJSA-N 0.000 description 1
- WIYMAHVYQQTUJC-QQJWGCFSSA-N CC(C[C@H]12)C1C2N(C)C Chemical compound CC(C[C@H]12)C1C2N(C)C WIYMAHVYQQTUJC-QQJWGCFSSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261648928P | 2012-05-18 | 2012-05-18 | |
| US61/648,928 | 2012-05-18 | ||
| PCT/US2013/041504 WO2013173672A1 (en) | 2012-05-18 | 2013-05-17 | Method for the preparation of thiadiazoles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104736518A CN104736518A (zh) | 2015-06-24 |
| CN104736518B true CN104736518B (zh) | 2017-10-13 |
Family
ID=49584318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201380026364.0A Expired - Fee Related CN104736518B (zh) | 2012-05-18 | 2013-05-17 | 制备噻二唑的方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9296735B2 (enExample) |
| EP (1) | EP2850057A4 (enExample) |
| JP (1) | JP6177894B2 (enExample) |
| CN (1) | CN104736518B (enExample) |
| CA (1) | CA2877026A1 (enExample) |
| IN (1) | IN2014KN02683A (enExample) |
| WO (1) | WO2013173672A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104788419B (zh) * | 2014-12-30 | 2018-12-21 | 西华大学 | 手性（2，2-二甲基-1，3二氧环戊烷-4-基）羟基甲磺酸盐及其制备方法和应用 |
| TWI840477B (en) | 2018-12-20 | 2024-05-01 | 德商拜耳廠股份有限公司 | Heterocyclyl pyridazine as fungicidal compounds |
| KR20230038704A (ko) | 2020-06-18 | 2023-03-21 | 바이엘 악티엔게젤샤프트 | 활성 화합물 조합물 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101671267A (zh) * | 2009-09-30 | 2010-03-17 | 浙江理工大学 | 一种直接将醛或脂肪族甲基酮的亚硫酸氢钠加成产物转变为相应肟的方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2544562A (en) * | 1947-07-18 | 1951-03-06 | Stanolind Oil & Gas Co | Process for recovering aldehydes and ketones |
| DK36784A (da) | 1983-02-25 | 1984-08-26 | Hoffmann La Roche | Fremgangsmaade til fremstilling af chirale aldehyder |
| DE19847823A1 (de) * | 1998-10-16 | 2000-04-20 | Aventis Pharma Gmbh | Substituierte Thiadiazolsulfonamide |
| JP4144978B2 (ja) | 1999-09-09 | 2008-09-03 | 富士フイルム株式会社 | １，２，４−チアジアゾール誘導体の合成法 |
| ATE521608T1 (de) | 2005-11-01 | 2011-09-15 | Array Biopharma Inc | Glucokinaseaktivatoren |
| JP5236499B2 (ja) | 2006-01-27 | 2013-07-17 | アレイ バイオファーマ、インコーポレイテッド | グルコキナーゼ活性化剤 |
| AU2007235558B2 (en) | 2006-03-24 | 2011-12-01 | Array Biopharma Inc. | 2 -aminopyridine analogs as glucokinase activators |
| WO2008091770A1 (en) | 2007-01-24 | 2008-07-31 | Array Biopharma Inc. | 2-aminopyridine derivatives as glucokinase activators |
| US8362037B2 (en) | 2007-03-23 | 2013-01-29 | Array Biopharma, Inc. | 2-aminopyridine analogs as glucokinase activators |
| EP3078662A1 (en) * | 2007-09-21 | 2016-10-12 | Array Biopharma, Inc. | Pyridin-2-yl-amino-1,2,4-thiadiazole derivatives as glucokinase activators for the treatment of diabetes mellitus |
-
2013
- 2013-05-17 WO PCT/US2013/041504 patent/WO2013173672A1/en not_active Ceased
- 2013-05-17 IN IN2683KON2014 patent/IN2014KN02683A/en unknown
- 2013-05-17 CA CA2877026A patent/CA2877026A1/en not_active Abandoned
- 2013-05-17 CN CN201380026364.0A patent/CN104736518B/zh not_active Expired - Fee Related
- 2013-05-17 EP EP13790539.4A patent/EP2850057A4/en not_active Withdrawn
- 2013-05-17 JP JP2015512873A patent/JP6177894B2/ja not_active Expired - Fee Related
- 2013-05-17 US US14/402,069 patent/US9296735B2/en not_active Expired - Fee Related
-
2016
- 2016-02-01 US US15/012,332 patent/US20160221985A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101671267A (zh) * | 2009-09-30 | 2010-03-17 | 浙江理工大学 | 一种直接将醛或脂肪族甲基酮的亚硫酸氢钠加成产物转变为相应肟的方法 |
Non-Patent Citations (2)
| Title |
|---|
| New General Method for Regio- and Stereoselective Allylic Substitution with Aryl and Alkenyl Coppers Derived from Grignard Reagent;Yohei Kiyotsukae et al.;《J. Org. Chem.》;20090206;第74卷;1939-1951 * |
| Synthesis of 2,3-O-isopropylidene-D-glyceraldehyde in High Chemical and Optical Purity: Observations on the Development of a Practical Bulk Process;Christopher R. Schmid et al.;《J. Org. Chem.》;19811231;第56卷;4056-4058 * |
Also Published As
| Publication number | Publication date |
|---|---|
| IN2014KN02683A (enExample) | 2015-05-08 |
| CN104736518A (zh) | 2015-06-24 |
| US20150141655A1 (en) | 2015-05-21 |
| CA2877026A1 (en) | 2013-11-21 |
| EP2850057A4 (en) | 2016-01-27 |
| JP2015517531A (ja) | 2015-06-22 |
| US9296735B2 (en) | 2016-03-29 |
| US20160221985A1 (en) | 2016-08-04 |
| WO2013173672A1 (en) | 2013-11-21 |
| JP6177894B2 (ja) | 2017-08-09 |
| EP2850057A1 (en) | 2015-03-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20171013 Termination date: 20190517 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |