CN104721684A - Traditional Chinese medicine for treating severe pneumonia and uses and preparing method thereof - Google Patents
Traditional Chinese medicine for treating severe pneumonia and uses and preparing method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine for treating severe pneumonia and uses and a preparing method thereof. The traditional Chinese medicine comprises all-grass of Ludwigia prostrata, common anemarrhena rhizome, towel gourd flower, sea-ear shell, Chinese angelica, heartleaf houttuynia herb, roughhaired holly root, herbaceous stem of Ephedra sinica, tatarian aster root, cape jasmine, root bark of white mulberry, snake gourd fruit, common andrographis herb, reed rhizome, rhizome of Alpinia japonica, seed of cowherb, muskroot-like semiaquilegia root and the like. The traditional Chinese medicine is safe and effective, has evident effect and features clear effect, safety and convenience, no toxic and side effect and ease of acceptance in treating severe pneumonia.
Description
Technical field
The present invention relates to the field of Chinese medicines, be related specifically to a kind of treat severe pneumonia Chinese medicine and preparation method and purposes.
Background technology
Severe pneumonia is the acute inflammation of pulmonary parenchyma, causes the reason of pneumonia a lot, and modal infection, chemistry, physics and the immunogenicity of comprising is damaged.The sorting technique of pneumonia is a lot, clinically for the ease for the treatment of, generally all presses etiological classification, comprises bacillary, mycoplasma pneumoniae, rickettsia, chlamydial, viral, fungoid, anaphylaxis, radioactivity and chemical pneumonitis etc.At present, pneumonia occupies the 5th of the cause of death.Cause of disease is the highest with antibacterial proportion.The reason causing severe pneumonia increasing is: along with antibiotic extensive use, pathogen has a very large change, simultaneously also frequent concurrent septicemia, empyema, pericarditis, respiratory distress syndrome etc., makes treatment more difficult.
Severe pneumonia often occurs that nervous, dyspnea in various degree and cyanosis increase the weight of; Severe patient occurs drowsiness and irritated, also can go into a coma, and usually prompting is due to severe depletion of oxygen and carbon dioxide retention and detoxifying function, causes cerebral edema and toxic encephalopthy, cardiac insufficiency.Early stage sign is not obvious, occurs rapid breathing, three depressions sign, flaring of alaenasi, cyanotic lips when breathing shallow, fast, serious, and it is thicker that initial lung only hears respiratory murmur, can smell middle or small moist rale later, the tiny moist rale of later stage audible or crepitation.When pneumonia focus merges expansion, pulmonary kowtows turbid, and hears tubular breath sound.Turbid and respiratory murmur reduction is obviously kowtowed in chest side, should consider with or without merging hydrothorax.Severe patient is out of breath, cyanosis, drowsiness, blood pressure is on the low side.Septicemia person, mucocutaneous have petechia, staring spells etc.Heart rate speeds suddenly, liver Progressive symmetric erythrokeratodermia increases, prompting cardiac insufficiency.Severe pneumonia belongs to the category such as Chinese medicine " cough ", " the syndrome of dyspnea ", " lung abscess ".At present, Chinese medicine formula weak effect, antiphlogistic effects is not as good as the antibiotics of Western medicine.But use antibiotics easily to cause side effect, and expensive, cause burden to family.
Summary of the invention
The object of the invention is to solve the deficiencies in the prior art, provide a kind of treat severe pneumonia Chinese medicine and preparation method and purposes.
For achieving the above object, the technical solution used in the present invention is: be made up of following weight item: Herba Ludwigiae Prostratae 1-5g, Rhizoma Anemarrhenae 2-6g, Flos Luffae 1-9g, Concha Haliotidis 2-8g, Radix Angelicae Sinensis 1-5g, Herba Houttuyniae 1-5g, Radix Ilicis Asprellae 2-6g, Herba Ephedrae 1-5g, Radix Asteris 2-8g, Fructus Gardeniae 2-8g, Cortex Mori 2-6g, Fructus Trichosanthis 1-8g, Herba Andrographis 2-8g, Rhizoma Phragmitis 2-6g, Alpinia japonica (Thunb.) Miq. 2-8g, Semen Vaccariae 1-4g, Radix Semiaquilegiae 1-8g, Herba Plantaginis 2-6g, Radix Glycyrrhizae 3-15g, Rhizoma Atractylodis Macrocephalae 1-4g, Caulis Lonicerae 1-10g, Radix Et Rhizoma Rhei 2-6g, Rhizoma Polygonati Verticillati 0.5-5g, Radix Notoginseng 2-10g, Impatientis 2-8g, Bulbus Lilii 2-8g, Radix Pulsatillae 1-5g, Folium Isatidis 1-5g, Fructus Arctii 2-6g, Herba Taraxaci 1-13g, Radix Platycodonis 2-9g, Semen Sterculiae Lychnophorae 2-9g, pomelo peel 1-10g, Flos Lonicerae 1-8g, Semen Armeniacae Amarum 1-8g, Radix Ginseng Rubra 0.05-2g, Semen Lepidii (Semen Descurainiae) 0.05-2g, Radix Aconiti Lateralis Preparata 0.05-2g, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 0.05-3g, Herba Peristrophes 1-9g, Herba Wedeliae Prostratae 1-7g.
Further, the present invention has following weight composition: Herba Ludwigiae Prostratae 1-4g, Rhizoma Anemarrhenae 2-5g, Flos Luffae 1-5g, Concha Haliotidis 2-7g, Radix Angelicae Sinensis 1-5g, Herba Houttuyniae 1-5g, Radix Ilicis Asprellae 2-6g, Herba Ephedrae 1-5g, Radix Asteris 2-8g, Fructus Gardeniae 2-8g, Cortex Mori 2-6g, Fructus Trichosanthis 1-5g, Herba Andrographis 2-5g, Rhizoma Phragmitis 2-6g, Alpinia japonica (Thunb.) Miq. 2-4g, Semen Vaccariae 1-4g, Radix Semiaquilegiae 1-8g, Herba Plantaginis 2-6g, Radix Glycyrrhizae 3 one 10g, Rhizoma Atractylodis Macrocephalae 1-4g, Caulis Lonicerae 1-8g, Radix Et Rhizoma Rhei 2-6g, Rhizoma Polygonati Verticillati 0.5-5g, Radix Notoginseng 2-8g, Impatientis 2-8g, Bulbus Lilii 2-8g, Radix Pulsatillae 1-5g, Folium Isatidis 1-5g, Fructus Arctii 2-6g, Herba Taraxaci 1-10g, Radix Platycodonis 2-9g, Semen Sterculiae Lychnophorae 2-9g, pomelo peel 1-8g, Flos Lonicerae 1-5g, Semen Armeniacae Amarum 1-5g, Radix Ginseng Rubra 0.05-2g, Semen Lepidii (Semen Descurainiae) 0.05-2g, Radix Aconiti Lateralis Preparata 0.05-2g, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 0.05-3g, Herba Peristrophes 1-9g, Herba Wedeliae Prostratae 1-7g.
Further, the present invention has following weight composition: Herba Ludwigiae Prostratae 2g, Rhizoma Anemarrhenae 2g, Flos Luffae 1g, Concha Haliotidis 2g, Radix Angelicae Sinensis 1g, Herba Houttuyniae 1g, Radix Ilicis Asprellae 2g, Herba Ephedrae 1g, Radix Asteris 1g, Fructus Gardeniae 2g, Cortex Mori 2g, Fructus Trichosanthis 1g, Herba Andrographis 2g, Rhizoma Phragmitis 2g, Alpinia japonica (Thunb.) Miq. 2g, Semen Vaccariae 1g, Radix Semiaquilegiae 2g, Herba Plantaginis 2g, Radix Glycyrrhizae 7g, Rhizoma Atractylodis Macrocephalae 1g, Caulis Lonicerae 1g, Radix Et Rhizoma Rhei 2g, Rhizoma Polygonati Verticillati 0.5g, Radix Notoginseng 2g, Impatientis 2g, Bulbus Lilii 2g, Radix Pulsatillae 1g, Folium Isatidis 3g, Fructus Arctii 2g, Herba Taraxaci 8g, Radix Platycodonis 2g, Semen Sterculiae Lychnophorae 2g, pomelo peel 7g, Flos Lonicerae 7g, Semen Armeniacae Amarum 6g, Radix Ginseng Rubra 0.05g, Semen Lepidii (Semen Descurainiae) 0.05g, Radix Aconiti Lateralis Preparata 0.05g, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 0.05g, Herba Peristrophes 1g, Herba Wedeliae Prostratae 1g.
Further, preparation process of the present invention: proportionally take above various Chinese medicine, pulverizes after mixing, and adding weight is Chinese crude drug 2-15 ethanol doubly, repeats extraction 3 times, decocts 0.5-3 hour at every turn, merging filtrate after filtering; Filtrate heating is concentrated in extractum, extractum vacuum drying is obtained dried cream powder, finally pulverizes dried cream powder; In dried cream powder, add pharmaceutically acceptable adjuvant be prepared into pharmaceutically conventional pharmaceutical preparation.
Further, the present invention is any one in oral liquid, tablet, capsule, powder.
Further, the invention provides a kind of application of Chinese medicine in preparation treatment severe pneumonia medicine for the treatment of severe pneumonia.
Further, the Chinese medicine for the treatment of severe pneumonia of the present invention and pharmaceutically acceptable carrier.
The present invention has cold expelling lung qi dispersing, the effect that clearing heat in QI system reduces phlegm.Compatibility of drugs of the present invention is reasonable, utilizes its mutual working in coordination with, improves curative effect, reduce untoward reaction, evident in efficacy, safe and reliable.The present invention develops in conjunction with clinical practice on the basis that traditional differential diagnosis in tcm treats, all medicines amount to the effect with clearing heat and purging lung, clearing away phlegm Dingchuan mutually, have determined curative effect, safe ready, have no side effect, acceptant feature at treatment severe pneumonia.
Detailed description of the invention
In order to make object of the present invention, technical scheme and advantage clearly understand, below in conjunction with specific embodiment, the present invention is further elaborated.
The pharmaceutical characteristic of each active component of the present invention is as follows:
Herba Ludwigiae Prostratae: bitter, cool.[function cures mainly] inducing diuresis to remove edema, heat-clearing and toxic substances removing.Harness the river swollen, gonorrhea, dysentery, leucorrhea, carbuncle, furuncle.
The Rhizoma Anemarrhenae: bitter, sweet, cold.[function cures mainly] clearing away heat-fire, promotes the production of body fluid and moisturizes.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
Flos Luffae: [function cures mainly] heat-clearing and toxic substances removing; To reduce phlegm arresting convulsion.Main variola does not rise; Laryngopharynx swelling and pain; Demented; Epilepsy syndrome.
Concha Haliotidis: return Liver Channel.[function cures mainly] suppressing the hyperactive liver and subsiding YANG, liver heat removing and eyesight improving.Dizzy for having a headache, cataract, blurring of vision, optic atrohic blindness nyctalopia.
Radix Angelicae Sinensis: sweet, acrid, warm.[function cures mainly] is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Herba Houttuyniae: pungent, is slightly cold.[function cures mainly] heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, inducing diuresis for treating stranguria syndrome.For lung abscess vomiting pus, expectorant dyspnea of heat type is coughed, hematodiarrhoea, pyretic stranguria, carbuncle sore tumefacting virus.
Radix Ilicis Asprellae: bitter sweet, cold.[function cures mainly] heat clearing away, promotes the production of body fluid, invigorates blood circulation, removing toxic substances.Cure cold, have a headache dizzy, calentura is yearningly dry, eruptive disease, diarrhea of heat type, lung abscess, hemoptysis, laryngalgia, hemorrhoidal bleeding, gonorrhea, carbuncle poison, traumatic injury.
Herba Ephedrae: return lung, urinary bladder channel.[function cures mainly] diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.For anemofrigid cold, uncomfortable in chestly to breath with cough, edema due to wind pathogen edema; Bronchial asthma.Herba ephedrae nourishing the lung to arrest cough.Be used for table disease to separate, asthma and cough.
Radix Asteris: pungent, bitter, temperature.[function cures mainly] nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm.Breath with cough for abundant expectoration, new chronic cough is coughed, chronic cough hemoptysis.
Fructus Gardeniae: bitter, cold.[function cures mainly] fruit: pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, jaundice dark coloured urine, blood strangury and dry pain, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles; External treatment bruise pain.
Cortex Mori: sweet, cold.[function cures mainly] eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema.For dyspnea and cough due to lung-heat, edema distension oliguria, appearance skin edema.
Fructus Trichosanthis: sweet, micro-hardship, cold.[function cures mainly] clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturizes laxation.For cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, blocked-up chest feeling of fullness, acute mastitis, lung abscess, and acute appendicitis swells and ache, constipation.
Herba Andrographis: bitter, cold.[function cures mainly] heat-clearing and toxic substances removing, removing heat from blood, detumescence.For cold, fever, laryngopharynx swelling and pain, aphtha of the mouth and tongue, pertussis chronic cough, dysentery, the puckery pain of pyretic stranguria, carbuncle skin infection, venom.
Rhizoma Phragmitis: sweet, cold.[function cures mainly] clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.For calentura excessive thirst, gastric heat is vomitted the sound of vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.
Alpinia japonica (Thunb.) Miq.: pungent, warm.[function cures mainly] dispelling wind and removing obstruction in the collateral, regulating QI to relieve pain.For rheumatic arthritis, traumatic injury, toothache, stomachache.
Semen Vaccariae: bitter is flat.[function cures mainly] promoting blood circulation to restore menstrual flow, stimulating milk secretion is subsided a swelling.For agalactia, amenorrhea, dysmenorrhea, acute mastitis swells and ache.
Radix Semiaquilegiae: sweet, bitter, cold.[function cures mainly] heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle furuncle, acute mastitis, scrofula, venom.
Herba Plantaginis: sweet, cold.[function cures mainly] clearing away heat and promoting diuresis, eliminates the phlegm, removing heat from blood, removing toxic substances.For edema oliguria, the puckery pain of pyretic stranguria, heat-damp in summer dysentery, phlegm-heat cough, hematemesis and epistaxis, carbuncle sore tumefacting virus.
Radix Glycyrrhizae: sweet, flat.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
The Rhizoma Atractylodis Macrocephalae: bitter, sweet, temperature.[function cures mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.
Caulis Lonicerae: sweet, cold.[function cures mainly] heat-clearing and toxic substances removing, dispelling wind dredging collateral.For epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle skin infection, beriberoid pyretic arthralgia, redness and swelling of joints burning pain.
Radix Et Rhizoma Rhei: bitter, cold.[function cures mainly] purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For conjunctival congestion pharyngeal swelling, gingivitis.Radix Et Rhizoma Rhei rushes down exerts oneself to delay, eliminating fire and detoxication.For pathogenic fire,toxin and furuncles.Charred Radix Et Rhizoma Rhei cooling blood and removing stasis stops blooding.Stasis of blood hemorrhage is had for heat in blood.
Rhizoma Polygonati Verticillati: sweet; Micro-hardship; Cool.[function cures mainly] spleen reinforcing lung moistening; Nourishing the liver; Removing toxicity for eliminating carbuncles.Main weakness of the spleen and stomach; Lung-dryness syndrome due to deficiency of YIN; Cough dry pharynx; Excessive rising of liver-YANG; Have a dizzy spell; Sore, carbuncle and painful swelling.
Radix Notoginseng: sweet, micro-hardship, temperature.[function cures mainly] dissipating blood stasis stops blooding, subduing swelling and relieving pain.For spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.
Impatientis: arduous, temperature.[function cures mainly] dispels the wind, and invigorates blood circulation, detumescence, pain relieving.Control articular rheumatic pain, traumatic injury, scrofula carbuncle, treat skin ulcer.
Bulbus Lilii: sweet, cold.[function cures mainly] nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.For deficiency of YIN chronic cough, sputum mixed with blood, fidgets due to deficiency is palpitated with fear, insomnia and dreamful sleep, absentminded.
The Radix Pulsatillae: bitter, cold.[function cures mainly] heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery.For toxic-heat and blood stasis, pudendal pruritus leukorrhagia, amebic dysentery.
Folium Isatidis: bitter, cold.[function cures mainly] heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.Join the army for pathogenic warmth, unconsciousness due to high fever, sends out speckle dermexanthesis, jaundice, hematodiarrhoea, mumps, sore throat, erysipelas, carbuncle.
Fructus Arctii: pungent, bitter, cold.[function cures mainly] dispelling wind and heat pathogens, lung qi dispersing rash, resolving toxin and disinhibiting the throat.For anemopyretic cold, cough with copious phlegm, measles, rubella, laryngopharynx swelling and pain, mumps erysipelas, carbuncle sore tumefacting virus.
Herba Taraxaci: bitter, sweet, cold.[function cures mainly] heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.
Radix Platycodonis: bitter, pungent is flat.[function cures mainly] lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Semen Sterculiae Lychnophorae: sweet, cold.[function cures mainly] clearing heat and moistening lung, liyan jiedu, loosening bowel to relieve constipation.For lung-heat celostomia, dry cough without phlegm, pharyngodynia with dryness, accumulation of heat just closes, headache conjunctival congestion.
Pomelo peel: bitter in the mouth, is slightly cold, tepor, nontoxic.[function cures mainly] the five internal organs blood stasis, aqueous vapor in abdomen, sets out and swollenly stays heat, anemofrigid-damp arthralgia, all pains of health.
Flos Lonicerae: sweet, cold.[function cures mainly] heat-clearing and toxic substances removing, wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat.
Semen Armeniacae Amarum: bitter, temperature, poisonous.[function cures mainly] expelling phlegm for arresting cough, relievings asthma, intestine moistening.Control exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation.
Radix Ginseng Rubra: sweet, micro-hardship, temperature.[function cures mainly] strongly invigorating primordial QI, multiple arteries and veins takes off admittedly, nourishing qi to stop.For weak body and prostration, cold extremities faint pulse, QI failing to control blood, metrostaxis; Heart failure, cardiogenic shock.
Semen Lepidii (Semen Descurainiae): pungent, bitter, Great Cold.[function cures mainly] eliminating pathogen from the lung for relieving asthma, line water detumescence.Stop up lung for sputum, dyspnea and cough with excessive sputum, fullness and distention in the chest and hypochondrium, must not put down sleeping, and ascites pleural fluid swells, dysuria; Pulmonary heart disease edema.
Radix Aconiti Lateralis Preparata: pungent, sweet is warm greatly; Poisonous.GUIXIN, kidney, spleen channel.[function with cure mainly] recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, by wind-cold damp pathogen.For YANG-depletion collapse, cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.
Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae): bitter, cool.[function cures mainly] heat-clearing and toxic substances removing, dampness removing, analgesic hemostatic.
Herba Peristrophes: pungent, micro-hardship is cool.[function cures mainly] juice induces sweat, heat-clearing and toxic substances removing, spasmolytic.For flu, laryngopharynx swelling and pain, diphtheria, infantile dyspepsia, infantile hyperpyrexia, carbuncle furuncle and phyma poison, venom.
Herba Wedeliae Prostratae: " Quanzhou book on Chinese herbal medicine ": " enter liver, spleen two warp." [function cures mainly] heat clearing away, removing toxic substances.Control throat moth, sore throat, diphtheria, pertussis, dyspnea and cough due to lung-heat, epistaxis, carbuncle, furuncle.
Embodiment 1
Concrete formula:
Herba Ludwigiae Prostratae 2g, Rhizoma Anemarrhenae 2g, Flos Luffae 1g, Concha Haliotidis 2g, Radix Angelicae Sinensis 1g, Herba Houttuyniae 1g, Radix Ilicis Asprellae 2g, Herba Ephedrae 1g, Radix Asteris 1g, Fructus Gardeniae 2g, Cortex Mori 2g, Fructus Trichosanthis 1g, Herba Andrographis 2g, Rhizoma Phragmitis 2g, Alpinia japonica (Thunb.) Miq. 2g, Semen Vaccariae 1g, Radix Semiaquilegiae 2g, Herba Plantaginis 2g, Radix Glycyrrhizae 7g, Rhizoma Atractylodis Macrocephalae 1g, Caulis Lonicerae 1g, Radix Et Rhizoma Rhei 2g, Rhizoma Polygonati Verticillati 0.5g, Radix Notoginseng 2g, Impatientis 2g, Bulbus Lilii 2g, Radix Pulsatillae 1g, Folium Isatidis 3g, Fructus Arctii 2g, Herba Taraxaci 8g, Radix Platycodonis 2g, Semen Sterculiae Lychnophorae 2g, pomelo peel 7g, Flos Lonicerae 7g, Semen Armeniacae Amarum 6g, Radix Ginseng Rubra 0.05g, Semen Lepidii (Semen Descurainiae) 0.05g, Radix Aconiti Lateralis Preparata 0.05g, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 0.05g, Herba Peristrophes 1g, Herba Wedeliae Prostratae 1g.
Above medicine preparation process: take above various Chinese medicine according to aforementioned proportion, pulverizes after mixing, adds the ethanol that weight is Chinese crude drug 5 times, repeat extraction 3 times, each decoction 2 hours, merging filtrate after filtering; Filtrate heating is concentrated in extractum, extractum vacuum drying is obtained dried cream powder, finally pulverizes dried cream powder; In dried cream powder, add capsule adjuvant be prepared into pharmaceutically conventional capsule preparations.
Embodiment 2
Concrete formula: Herba Ludwigiae Prostratae 2g, Rhizoma Anemarrhenae 2g, Flos Luffae 1g, Concha Haliotidis 2g, Radix Angelicae Sinensis 1g, Herba Houttuyniae 1g, Radix Ilicis Asprellae 2g, Herba Ephedrae 5g, Radix Asteris 4g, Fructus Gardeniae 2g, Cortex Mori 6g, Fructus Trichosanthis 4g, Herba Andrographis 5g, Rhizoma Phragmitis 3g, Alpinia japonica (Thunb.) Miq. 3g, Semen Vaccariae 2g, Radix Semiaquilegiae 5g, Herba Plantaginis 2g, Radix Glycyrrhizae 4g, Rhizoma Atractylodis Macrocephalae 2g, Caulis Lonicerae 2g, Radix Et Rhizoma Rhei 4g, Rhizoma Polygonati Verticillati 0.05g, Radix Notoginseng 2g, Impatientis 2g, Bulbus Lilii 8g, Radix Pulsatillae 1g, Folium Isatidis 1g, Fructus Arctii 2g, Herba Taraxaci 6g, Radix Platycodonis 3g, Semen Sterculiae Lychnophorae 4g, pomelo peel 3g, Flos Lonicerae 4g, Semen Armeniacae Amarum 1g, Radix Ginseng Rubra 0.05g, Semen Lepidii (Semen Descurainiae) 0.05g, Radix Aconiti Lateralis Preparata 0.05g, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 0.05g, Herba Peristrophes 2g, Herba Wedeliae Prostratae 2g.
Above medicine preparation process: take above various Chinese medicine according to aforementioned proportion, pulverizes after mixing, adds the ethanol that weight is Chinese crude drug 5 times, repeat extraction 3 times, each decoction 3 hours, merging filtrate after filtering; Filtrate heating is concentrated in extractum, extractum vacuum drying is obtained dried cream powder, finally pulverizes dried cream powder; The adjuvant adding oral formulations in dried cream powder is prepared into pharmaceutically conventional oral liquid.
Embodiment 3
Herba Ludwigiae Prostratae 3g, Rhizoma Anemarrhenae 3g, Flos Luffae 3g, Concha Haliotidis 5g, Radix Angelicae Sinensis 2g, Herba Houttuyniae 4g, Radix Ilicis Asprellae 2g, Herba Ephedrae 3g, Radix Asteris 2g, Fructus Gardeniae 3g, Cortex Mori 3g, Fructus Trichosanthis 2g, Herba Andrographis 3g, Rhizoma Phragmitis 2g, Alpinia japonica (Thunb.) Miq. 4g, Semen Vaccariae 1g, Radix Semiaquilegiae 2g, Herba Plantaginis 3g, Radix Glycyrrhizae 4g, Rhizoma Atractylodis Macrocephalae 2g, Caulis Lonicerae 2g, Radix Et Rhizoma Rhei 4g, Rhizoma Polygonati Verticillati 0.05g, Radix Notoginseng 2g, Impatientis 2g, Bulbus Lilii 3g, Radix Pulsatillae 1g, Folium Isatidis 5g, Fructus Arctii 4g, Herba Taraxaci 6g, Radix Platycodonis 3g, Semen Sterculiae Lychnophorae 4g, pomelo peel 3g, Flos Lonicerae 4g, Semen Armeniacae Amarum 1g, Radix Ginseng Rubra 0.05g, Semen Lepidii (Semen Descurainiae) 0.05g, Radix Aconiti Lateralis Preparata 0.05g, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 0.05g, Herba Peristrophes 2g, Herba Wedeliae Prostratae 2g.
Above medicine preparation process: take above various Chinese medicine according to aforementioned proportion, pulverizes after mixing, adds the ethanol that weight is Chinese crude drug 5 times, repeat extraction 3 times, each decoction 3 hours, merging filtrate after filtering; Filtrate heating is concentrated in extractum, extractum vacuum drying is obtained dried cream powder, finally pulverizes dried cream powder; In dried cream powder, add additive of tablet be prepared into pharmaceutically conventional tablet.
Embodiment 4
Clinical trial
Diagnostic criteria
With reference to " Ministry of Health of the People's Republic of China, pediatric disease diagnostic criteria. Shanghai: publishing house of Shanghai Medical Univ, 1997:120-127. " diagnostic criteria worked out.Screening patient, wherein man 39 example, female 41 example, age 20-70 year.
Usage and consumption: take embodiment 3 day, one day three times.It within 7 days, was 1 course for the treatment of.
Curative effect determinate standard
" healing ": Clinical symptom and sign disappears, recovers normal.
" effective ": the basic or major part of Clinical symptom and sign disappears.
" effectively ": clinical symptoms is clearly better.
Engineering noise: Clinical symptom and sign is without improvement.
Therapeutic effect: clinical cure 86%; Effective 91%; Invalid 9%.
Model case
1, Song, female, 31 years old.Pneumonia, lethargy, flaring of alaenasi, obviously require great effort during air-breathing.After giving 2 courses for the treatment of of the present embodiment 3 tablet, patients symptomatic disappears, and recovery from illness, does not recur so far.
2, Zhao so-and-so, man, 48 years old.Cough 10 days, general fatigue, headache, the few Se Baiyi of expectorant coughs up; Body of the tongue is light red, thready and stringy pulse, and blood cell analysis is normal, and Thoracic CT scan shows twice pneumonia.Take the embodiment of the present invention 3.After 1 course for the treatment of, heating, cough symptom greatly alleviate, after continuing to serve on 2 courses for the treatment of, and health complete recovery of health.
3, secondary certain, man, 23 years old, coughs 20 days, sick fatigue is drenched with rain and is suffered from cold, nasal obstruction, anemophobia, general fatigue, the few Se Baiyi of expectorant coughs up, and without dry pharynx itching throat, mouth is not dry bitter, white and greasy fur is slightly thick, and matter is light red, thready and stringy pulse, blood cell analysis is normal, and Thoracic CT scan shows twice pneumonia, after taking 2 courses for the treatment of of the embodiment of the present invention 3 tablet, heating, cough transference cure, after continuing to serve on 2 courses for the treatment of, health complete recovery of health.
3, Peng so-and-so, female, 36 years old, heating, cough with asthma, body temperature remains on more than 38.9 DEG C, and lasting 7d does not move back.Rapid breathing, cough with asthma, flaring nares, three depressions sign is obvious, yellowish urine, and just thousand, body of the tongue red drop, thready and rapid pulse.After taking 2 courses for the treatment of of the embodiment of the present invention 3 tablet, heating, cough transference cure, after continuing to serve on 2 courses for the treatment of, health complete recovery of health.。
Although be described preferred embodiment of the present invention above; but the present invention is not limited to above-mentioned detailed description of the invention; above-mentioned detailed description of the invention is only schematic; be not restrictive; those of ordinary skill in the art is under enlightenment of the present invention; do not departing under the ambit that present inventive concept and claim protects, can also make a lot of form, these all belong within protection scope of the present invention.
Claims (7)
1. treat the Chinese medicine of severe pneumonia for one kind, it is characterized in that: be made up of following parts by weight of component: Herba Ludwigiae Prostratae 1-5g, Rhizoma Anemarrhenae 2-6g, Flos Luffae 1-9g, Concha Haliotidis 2-8g, Radix Angelicae Sinensis 1-5g, Herba Houttuyniae 1-5g, Radix Ilicis Asprellae 2-6g, Herba Ephedrae 1-5g, Radix Asteris 2-8g, Fructus Gardeniae 2-8g, Cortex Mori 2-6g, Fructus Trichosanthis 1-8g, Herba Andrographis 2-8g, Rhizoma Phragmitis 2-6g, Alpinia japonica (Thunb.) Miq. 2-8g, Semen Vaccariae 1-4g, Radix Semiaquilegiae 1-8g, Herba Plantaginis 2-6g, Radix Glycyrrhizae 3-15g, Rhizoma Atractylodis Macrocephalae 1-4g, Caulis Lonicerae 1-10g, Radix Et Rhizoma Rhei 2-6g, Rhizoma Polygonati Verticillati 0.5-5g, Radix Notoginseng 2-10g, Impatientis 2-8g, Bulbus Lilii 2-8g, Radix Pulsatillae 1-5g, Folium Isatidis 1-5g, Fructus Arctii 2-6g, Herba Taraxaci 1-13g, Radix Platycodonis 2-9g, Semen Sterculiae Lychnophorae 2-9g, pomelo peel 1-10g, Flos Lonicerae 1-8g, Semen Armeniacae Amarum 1-8g, Radix Ginseng Rubra 0.05-2g, Semen Lepidii (Semen Descurainiae) 0.05-2g, Radix Aconiti Lateralis Preparata 0.05-2g, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 0.05-3g, Herba Peristrophes 1-9g, Herba Wedeliae Prostratae 1-7g.
2. a kind of Chinese medicine for the treatment of severe pneumonia according to claim 1, it is characterized in that: Herba Ludwigiae Prostratae 1-4g, Rhizoma Anemarrhenae 2-5g, Flos Luffae 1-5g, Concha Haliotidis 2-7g, Radix Angelicae Sinensis 1-5g, Herba Houttuyniae 1-5g, Radix Ilicis Asprellae 2-6g, Herba Ephedrae 1-5g, Radix Asteris 2-8g, Fructus Gardeniae 2-8g, Cortex Mori 2-6g, Fructus Trichosanthis 1-5g, Herba Andrographis 2-5g, Rhizoma Phragmitis 2-6g, Alpinia japonica (Thunb.) Miq. 2-4g, Semen Vaccariae 1-4g, Radix Semiaquilegiae 1-8g, Herba Plantaginis 2-6g, Radix Glycyrrhizae 3-10g, Rhizoma Atractylodis Macrocephalae 1-4g, Caulis Lonicerae 1-8g, Radix Et Rhizoma Rhei 2-6g, Rhizoma Polygonati Verticillati 0.5-5g, Radix Notoginseng 2-8g, Impatientis 2-8g, Bulbus Lilii 2-8g, Radix Pulsatillae 1-5g, Folium Isatidis 1-5g, Fructus Arctii 2-6g, Herba Taraxaci 1-10g, Radix Platycodonis 2-9g, Semen Sterculiae Lychnophorae 2-9g, pomelo peel 1-8g, Flos Lonicerae 1-5g, Semen Armeniacae Amarum 1-5g, Radix Ginseng Rubra 0.05-2g, Semen Lepidii (Semen Descurainiae) 0.05-2g, Radix Aconiti Lateralis Preparata 0.05-2g, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 0.05-3g, Herba Peristrophes 1-9g, Herba Wedeliae Prostratae 1-7g.
3. a kind of Chinese medicine for the treatment of severe pneumonia according to claim 1 and 2, it is characterized in that: Herba Ludwigiae Prostratae 2g, Rhizoma Anemarrhenae 2g, Flos Luffae 1g, Concha Haliotidis 2g, Radix Angelicae Sinensis 1g, Herba Houttuyniae 1g, Radix Ilicis Asprellae 2g, Herba Ephedrae 1g, Radix Asteris 1g, Fructus Gardeniae 2g, Cortex Mori 2g, Fructus Trichosanthis 1g, Herba Andrographis 2g, Rhizoma Phragmitis 2g, Alpinia japonica (Thunb.) Miq. 2g, Semen Vaccariae 1g, Radix Semiaquilegiae 2g, Herba Plantaginis 2g, Radix Glycyrrhizae 7g, Rhizoma Atractylodis Macrocephalae 1g, Caulis Lonicerae 1g, Radix Et Rhizoma Rhei 2g, Rhizoma Polygonati Verticillati 0.5g, Radix Notoginseng 2g, Impatientis 2g, Bulbus Lilii 2g, Radix Pulsatillae 1g, Folium Isatidis 3g, Fructus Arctii 2g, Herba Taraxaci 8g, Radix Platycodonis 2g, Semen Sterculiae Lychnophorae 2g, pomelo peel 7g, Flos Lonicerae 7g, Semen Armeniacae Amarum 6g, Radix Ginseng Rubra 0.05g, Semen Lepidii (Semen Descurainiae) 0.05g, Radix Aconiti Lateralis Preparata 0.05g, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 0.05g, Herba Peristrophes 1g, Herba Wedeliae Prostratae 1g.
4. a kind of Chinese medicine for the treatment of severe pneumonia according to claims 1 to 3, is characterized in that: further comprising the steps of:
Proportionally take above various Chinese medicine, pulverize after mixing, adding weight is Chinese crude drug 2-15 ethanol doubly, repeats extraction 3 times, decocts 0.5-3 hour at every turn, merging filtrate after filtering; Filtrate heating is concentrated in extractum, extractum vacuum drying is obtained dried cream powder, finally pulverizes dried cream powder; In dried cream powder, add pharmaceutically acceptable adjuvant be prepared into pharmaceutically conventional pharmaceutical preparation.
5. a kind of Chinese medicine for the treatment of severe pneumonia according to claim 4, is characterized in that: be any one in oral liquid, tablet, capsule, powder.
6. a kind of application of Chinese medicine in preparation treatment severe pneumonia medicine for the treatment of severe pneumonia according to claims 1 to 3.
7. treat a Chinese medicine for severe pneumonia, comprise the Chinese medicine of claim 1 or the treatment severe pneumonia any one of 2 or 3 and pharmaceutically acceptable carrier.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101269168A (en) * | 2008-04-14 | 2008-09-24 | 王鲁云 | Traditional Chinese medicine for treating cough and asthma of children |
| CN102988862A (en) * | 2012-12-17 | 2013-03-27 | 凤台县中医院 | Traditional Chinese medicine for treating pneumonia |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101269168A (en) * | 2008-04-14 | 2008-09-24 | 王鲁云 | Traditional Chinese medicine for treating cough and asthma of children |
| CN102988862A (en) * | 2012-12-17 | 2013-03-27 | 凤台县中医院 | Traditional Chinese medicine for treating pneumonia |
Non-Patent Citations (1)
| Title |
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| 梅广源主编: "《中西医结合急诊内科学》", 31 January 2008, 科学出版社 * |
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Application publication date: 20150624 |