CN104707006A - Radioactive preparation capable of promoting blood circulation and dredging meridians for cataract patients and preparation thereof - Google Patents
Radioactive preparation capable of promoting blood circulation and dredging meridians for cataract patients and preparation thereof Download PDFInfo
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Abstract
The invention discloses a radioactive preparation capable of promoting blood circulation and dredging meridians for cataract patients and a preparation method thereof. The radioactive preparation is prepared from the following main raw material drugs in part by weight: 12-20 parts of Angelica sinensis, 11-16 parts of corydalis bungeana, 10-18 parts of polygala tenuifolia, 10-18 parts of root of Japanese spiraea, 9-18 parts of medicated leaven, 15-19 parts of herb of manybranch meadowrue, 14-18 parts of Polygonum multiflorum, 13-20 parts of cymbidium ensifolium flowers, 9-13 parts of Saussurea nigrescens, 15-23 parts of rhizoma alismatis, 8-15 parts of Gorgon fruit, 4-7 parts of Lepus tolai pallas, 7-13 parts of ephedra, 8-15 parts of amaranth, 12-18 parts of Schisandra chinensis and 9-13 parts of Pleioblastus amarus leaves. The radioactive preparation has the advantages of treating both principal and secondary aspect of diseases, being definite in therapeutic effect, difficult to recur after recovery, risk-free, low in treatment cost and free of toxic and side effects.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation and preparation method thereof.
Background technology
Radiational cataract refers to because lonizing radiation, the eye lens generation research of chaotic phenomenon caused.Also traumatic cataract can be included into.Radiational cataract is very common, occurs that the size of cataract and radiological dose has certain relation.If single dose is excessive, can lens damage be caused, and the irradiation of Chronic Intermittent low dose, also there is build-up effect.Because observational technique and judge that the standard of lenticular opacity is different, lens damage is also different.Radiational cataract is the common clinically a kind of disease of occupation disease, in the professional radiation disease that China has diagnosed, be in second.Mainly contain with Types Below: the cataract 1, caused by infrared ray.The multiple workman being born in glass factory and steel mill, because of fusing high temp glass and steel plant produce short infrared absorbed after, produce lenticular opacity.First after date cortex has cavity, point-like and thread-like opacity, similar spider reticulation, has golden yellow crystalline gloss.Develop into plate-like muddiness gradually later.Finally develop into total cataract.Sometimes also little cloudy is had under anterior capsule.2, the cataract of caused by ionizing radiation.The ray of ionizing radiation comprises neutron, x-ray, γ line and high-octane β line, can cause cataract after irradiating crystal.Incubation period differs in length, and has direct relation with radiological dose size and age.Dosage is large, age little person is short for incubation period.Have cavity and canescence granular cloud under initial stage posterior lens capsule film, little point-like muddiness develops into ring-type muddiness gradually, and anterior capsule hypopallium has point-like, wire and featheriness muddy, extremely outwards radiates in the past.Can there be plate-like and wedge shape muddiness in later stage, finally forms total cataract.3, cataract caused by microwave.Microwave derives from solar rays, cosmic ray and TV, radar, microwave oven etc.Heavy dose of microwave can produce and be similar to ultrared heat effect.Crystalline lens, to microwave susceptible, because the dosage difference of microwave can produce the different infringement of crystalline lens, is similar to the cataract caused by infrared ray.Crystalline lens is muddy and frontal cortex pinniform muddiness under there is cortex point-like muddiness, Lens capsular.
Application publication number CN 102973775 A(application number 201210554072.1) Chinese patent literature disclose one and treat cataractous medicine, be made up of the raw material of following parts by weight: Semen Cuscutae 10-20 part, Flos Chrysanthemi 5-10 part, Sanguis Draxonis 5-10 part, Radix Puerariae 10-20 part, Radix Scutellariae 15-20 part, Flos Eriocauli 13-15 part, Fel Bovis seu Bubali 5-20 part, Herba Menthae 4-15 part, Semen phaseoli radiati 13-18 part, Fructus Lycii 14-23 part, Radix Schisandrae Bicoloris 8-15 part, Radix Angelicae Sinensis 6-19 part, Radix Aconiti Lateralis Preparata 8-20 part, Cornu Cervi Pantotrichum 15-20 part, Colla Corii Asini 10-20 part, longan 5-10 part, Rhizoma Acori Graminei 2-8 part, Radix Polygalae 3-9 part, Rhizoma Anemarrhenae 4-7 part, Semen Plantaginis 5-10 part, Rhizoma Dioscoreae 2-5 part, Os Sepiae 15-20 part.Application publication number CN 103341020 A(application number 201310320625.1) Chinese patent literature disclose a kind of Chinese medicine preparation and preparation method of radiotherapy cataract, the raw material of this Chinese medicine preparation effective ingredient consists of Cortex Fraxini, Herba Centellae, Semen Astragali Complanati, Herba Coreopsis tinctoria, jasmine, the Flos Sophorae Immaturus, Herba Cassiae Nomamis, Herba Senecionis Scandentis, Cacumen Securinegae Suffruticosae, Herba Houttuyniae, Flos Inulae, Herba Reineckeae Carneae, Radix Gentianae, Herba Pratiae Nummulariae, Cortex Acanthopancis and Semen Sesami Nigrum.Application publication number CN 104208315 A(application number 201410412487.4) Chinese patent literature disclose one and be used for the treatment of cataractous eye drop, make eye drop by Flos Inulae, Thallus Laminariae (Thallus Eckloniae), Fructus Lycii, Flos Chrysanthemi, Fructus Schisandrae Chinensis, Fructus Ligustri Lucidi, Rhizoma Acori Graminei, Semen Plantaginis, Radix Angelicae Sinensis.
Up to now specific medicament be there is no to the treatment of radiational cataract.The at present collyrium such as main catalin, card woods excellent, phacolin, glutathion, catalin, BDL, treatment is not suitable for the patient performed the operation in early days or temporarily, but its definite curative effect waits summary research.And adopt cataractopiesis to treat, the postoperative crystalline lens of implantable artificial within the eye or wear glasses or corneal contact lens to correct defects of vision, operative treatment risk is high, and medical expense is high.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation and preparation method thereof.Determined curative effect of the present invention, treating both the principal and secondary aspects of a disease, more after not easily recurrence, devoid of risk, medical expense low, have no side effect.
Technical scheme of the present invention is:
Radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation, takes off the primary raw material medicine stating weight proportion and is prepared from: Radix Angelicae Sinensis 12-20, Herba Violae 11-16, Radix Polygalae 10-18, Radix spiraeae japonicae 10-18, Massa Medicata Fermentata 9-18, Herba Thalictri Ramosi 15-19, Radix Polygoni Multiflori 14-18, Flos Cymbidii Ensifolii 13-20, Herba saussureae nigrescentis 9-13, Rhizoma Alismatis 15-23, Semen Euryales 8-15, Faeces Leporis 4-7, Herba Ephedrae 7-13, Herba Amaranthi tricoloris 8-15, Fructus Schisandrae Chinensis 12-18, Folium Pleioblasti 9-13.
Radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Radix Angelicae Sinensis 14-17, Herba Violae 13-15, Radix Polygalae 13-15, Radix spiraeae japonicae 12-15, Massa Medicata Fermentata 11-16, Herba Thalictri Ramosi 16-18, Radix Polygoni Multiflori 15-17, Flos Cymbidii Ensifolii 14-18, Herba saussureae nigrescentis 10-12, Rhizoma Alismatis 17-20, Semen Euryales 9-12, Faeces Leporis 4.5-6, Herba Ephedrae 9-12, Herba Amaranthi tricoloris 10-13, Fructus Schisandrae Chinensis 14-16, Folium Pleioblasti 10-12.
Radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: Radix Angelicae Sinensis 15, Herba Violae 14, Radix Polygalae 14, Radix spiraeae japonicae 13, Massa Medicata Fermentata 12, Herba Thalictri Ramosi 17, Radix Polygoni Multiflori 16, Flos Cymbidii Ensifolii 16, Herba saussureae nigrescentis 11, Rhizoma Alismatis 18, Semen Euryales 11, Faeces Leporis 5, Herba Ephedrae 10, Herba Amaranthi tricoloris 11, Fructus Schisandrae Chinensis 15, Folium Pleioblasti 11.
Present invention also offers the preparation method aforementioned radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation being made pharmaceutically acceptable powder, pill, granule, Tablet and Capsula agent.
The preparation method of described powder is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/3-3/5(preferably talc powder of Semen Euryales weight is 2/5 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. seven sieves;
(2) add water in pot, amount of water be the 9-14 of Folium Pleioblasti weight doubly (preferred amount of water is 13 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-8-15 of boiling minute (preferably maintaining micro-boiling 12 minutes), from fire, remove slag extracting juice;
(3) all the other the 14 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. seven sieves;
(4) step (1) and step (3) gained fine powder are fully mixed;
(5) step (2) gained medicine juice is condensed into the paste medicine (preferably step (2) gained medicine juice being condensed into the paste medicine that relative density is 1.36) that relative density is 1.33-1.37, add 95% ethanol and gained paste medicine grinds altogether, add the fine powder after step (4) mixing again, grind well, drying 24 hours in the vacuum drying oven of 50 DEG C, be distributed into and often wrap 5g, sterile packaged, to obtain final product.
The preparation method of described pill is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/3-3/5(preferably talc powder of Semen Euryales weight is 2/5 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. six sieves;
(2) add water in pot, amount of water be the 9-14 of Folium Pleioblasti weight doubly (preferred amount of water is 13 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-8-15 of boiling minute (preferably maintaining micro-boiling 12 minutes), from fire, remove slag extracting juice;
(3) all the other the 14 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) step (1) and step (3) gained fine powder are fully mixed, with the general ball of step (2) gained medicine juice, make the pill of the heavy 0.2g of every ball.
The preparation method of described granule is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/3-3/5(preferably talc powder of Semen Euryales weight is 2/5 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. six sieves;
(2) add water in pot, amount of water be the 9-14 of Folium Pleioblasti weight doubly (preferred amount of water is 13 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-8-15 of boiling minute (preferably maintaining micro-boiling 12 minutes), from fire, remove slag extracting juice;
(3) all the other the 14 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) by step (1) and step (3) gained fine powder mix homogeneously, fine powder after mix homogeneously and mass fraction be 16% starch slurry make altogether, make soft material, 14 mesh sieves are granulated, wet granular spreads out in enamel tray, to put in baking oven 60 DEG C and is dried to pellet moisture and controls about 4%, be more evenly sprayed at by step (2) gained medicine juice in dry granule, sealing placement 60 minutes, packs and get final product.
The preparation method of described tablet is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/3-3/5(preferably talc powder of Semen Euryales weight is 2/5 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. six sieves;
(2) add water in pot, amount of water be the 9-14 of Folium Pleioblasti weight doubly (preferred amount of water is 13 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-8-15 of boiling minute (preferably maintaining micro-boiling 12 minutes), from fire, remove slag extracting juice;
(3) all the other the 14 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) by step (1) and step (3) gained fine powder mix homogeneously, fine powder after mix homogeneously and mass fraction be 14% starch slurry make altogether, make soft material, 14 mesh sieves are granulated, and wet granular spreads out in enamel tray, to put in baking oven 60 DEG C and are dried to pellet moisture and control about 4%, again step (2) gained medicine juice is evenly sprayed in dry granule, tabletting, the heavy 0.25g of every sheet, to obtain final product.
The preparation method of described capsule is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/3-3/5(preferably talc powder of Semen Euryales weight is 2/5 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. six sieves;
(2) add water in pot, amount of water be the 9-14 of Folium Pleioblasti weight doubly (preferred amount of water is 13 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-8-15 of boiling minute (preferably maintaining micro-boiling 12 minutes), from fire, remove slag extracting juice;
(3) step (2) gained medicine juice is condensed into the thick paste (preferably step (2) gained medicine juice being condensed into the thick paste that relative density is 1.34) that relative density is 1.32-1.35, dry at the temperature of 55 DEG C-65 DEG C (preferably dry at the temperature of 60 DEG C), dry 12-28 hour (preferably dry 15 hours), be ground into fine powder, cross No. six sieves;
(4) all the other the 14 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(5) by step (1), step (3) and step (4) gained fine powder mix homogeneously, drying 12 hours at the temperature of 65 DEG C, spread out in stainless steel disc, thickness is 15-25mm, microwave sterilizating 3-6 minute (preferred microwave sterilizating 4 minutes), loads zero capsule, every capsules is equipped with medicated powder 0.35g, by the capsule polishing in buffing machine installed, pressing plate, to obtain final product.
Radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation taking convenience provided by the invention, to be easy to carry.In addition, excellent results of the present invention also shows:
1, determined curative effect;
2, devoid of risk, medical expense low, have no side effect, mental pressure and the economic pressures of patient can be alleviated, patient
Be easy to accept;
3, preparation method is simple;
4, there is invigorating the spleen and regulating the stomach, spleen reinforcing reinforced the kidney, clear away heart-fire regulate the flow of vital energy, promoting blood circulation to remove obstruction in the collateral, tonify Qi of the kidney, the effect such as clearing away heat to improve acuity of vision, radiational cataract can be made to reach thorough healing, and treating both the principal and secondary aspects of a disease, not easily recur more.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation, the primary raw material medicine getting following weight parts is prepared from (every part is 120g): Radix Angelicae Sinensis 12 parts, Herba Violae 11 parts, Radix Polygalae 10 parts, Radix spiraeae japonicae 10 parts, Massa Medicata Fermentata 9 parts, Herba Thalictri Ramosi 15 parts, Radix Polygoni Multiflori 14 parts, Flos Cymbidii Ensifolii 13 parts, Herba saussureae nigrescentis 9 parts, Rhizoma Alismatis 15 parts, Semen Euryales 8 parts, Faeces Leporis 4 parts, 7 parts, Herba Ephedrae, Herba Amaranthi tricoloris 8 parts, Fructus Schisandrae Chinensis 12 parts, Folium Pleioblasti 9 parts.
The preparation method of above-mentioned radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation pill is:
(1) put in pot by Pulvis Talci, talcous weight is 2/5 of Semen Euryales weight, and heating is with high heat stirred, and when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cools, and is ground into fine powder, crosses No. six sieves;
(2) add water in pot, amount of water is 13 times of Folium Pleioblasti weight, and put into Folium Pleioblasti after being heated to boil, remain micro-and boil 12 minutes, from fire, remove slag extracting juice;
(3) all the other the 14 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) step (1) and step (3) gained fine powder are fully mixed, with the general ball of step (2) gained medicine juice, make the pill of the heavy 0.2g of every ball.
The using method of gained radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation pill of the present invention is: oral, every day three times, each 3-5 ball, warm water takes.
embodiment 2radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation, the primary raw material medicine getting following weight parts is prepared from (every part is 120g): Radix Angelicae Sinensis 20 parts, Herba Violae 16 parts, Radix Polygalae 18 parts, Radix spiraeae japonicae 18 parts, Massa Medicata Fermentata 18 parts, Herba Thalictri Ramosi 19 parts, Radix Polygoni Multiflori 18 parts, Flos Cymbidii Ensifolii 20 parts, Herba saussureae nigrescentis 13 parts, Rhizoma Alismatis 23 parts, Semen Euryales 15 parts, Faeces Leporis 7 parts, 13 parts, Herba Ephedrae, Herba Amaranthi tricoloris 15 parts, Fructus Schisandrae Chinensis 18 parts, Folium Pleioblasti 13 parts.
The preparation method of above-mentioned radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation granules agent is:
(1) put in pot by Pulvis Talci, talcous weight is 2/5 of Semen Euryales weight, and heating is with high heat stirred, and when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cools, and is ground into fine powder, crosses No. six sieves;
(2) add water in pot, amount of water is 13 times of Folium Pleioblasti weight, and put into Folium Pleioblasti after being heated to boil, remain micro-and boil 12 minutes, from fire, remove slag extracting juice;
(3) all the other the 14 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) by step (1) and step (3) gained fine powder mix homogeneously, fine powder after mix homogeneously and mass fraction be 16% starch slurry make altogether, make soft material, 14 mesh sieves are granulated, wet granular spreads out in enamel tray, to put in baking oven 60 DEG C and is dried to pellet moisture and controls about 4%, be more evenly sprayed at by step (2) gained medicine juice in dry granule, sealing placement 60 minutes, packs and get final product.
model case one:week XX, female, 55 years old.Main suit: weak, dizzy, headache, more than 10 years of visual deterioration.Patient is radiation technician, is engaged in Chest X-rays work, and personal protective equipment has lead apron and plumbous chair.Occurred before 10 years weak, dizzy, headache, visual deterioration symptom.Be diagnosed as radiational cataract, invalid through multi-treatment.Inspection to show after bicrystal under capsule and under front capsule lamellar muddy, see cavity under right eye posterior lens capsule, the radial muddiness of cortex.Binocular vision 0.8.Be diagnosed as radiational cataract.Take the agent of the present embodiment gained radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation granules, every day three times, each 10g, boiled water is taken after mixing it with water.Take 2 months, the symptom such as weak, dizzy, headache obviously alleviates, and conscious vision is recovered to some extent.Continue to take two months all diseases to disappear, vision restoration is normal.Follow-up observation is not recurred.
embodiment 3radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation, the primary raw material medicine getting following weight parts is prepared from (every part is 120g): take off the primary raw material medicine stating weight proportion and be prepared from: Radix Angelicae Sinensis 14 parts, Herba Violae 13 parts, Radix Polygalae 13 parts, Radix spiraeae japonicae 12 parts, Massa Medicata Fermentata 11 parts, Herba Thalictri Ramosi 16 parts, Radix Polygoni Multiflori 15 parts, Flos Cymbidii Ensifolii 14 parts, Herba saussureae nigrescentis 10 parts, Rhizoma Alismatis 17 parts, Semen Euryales 9 parts, Faeces Leporis 4.5 parts, 9 parts, Herba Ephedrae, Herba Amaranthi tricoloris 10 parts, Fructus Schisandrae Chinensis 14 parts, Folium Pleioblasti 10 parts.
The preparation method of above-mentioned radiational cataract patient promoting blood circulation to remove obstruction in the collateral formulation tablet is:
(1) put in pot by Pulvis Talci, talcous weight is 2/5 of Semen Euryales weight, and heating is with high heat stirred, and when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cools, and is ground into fine powder, crosses No. six sieves;
(2) add water in pot, amount of water is 13 times of Folium Pleioblasti weight, and put into Folium Pleioblasti after being heated to boil, remain micro-and boil 12 minutes, from fire, remove slag extracting juice;
(3) all the other the 14 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) by step (1) and step (3) gained fine powder mix homogeneously, fine powder after mix homogeneously and mass fraction be 14% starch slurry make altogether, make soft material, 14 mesh sieves are granulated, and wet granular spreads out in enamel tray, to put in baking oven 60 DEG C and are dried to pellet moisture and control about 4%, again step (2) gained medicine juice is evenly sprayed in dry granule, tabletting, the heavy 0.25g of every sheet, to obtain final product.
model case two:xu XX, man, 47 years old.Main suit: dizziness headache, fatigue and weak, visual deterioration 5 years.Patient is medical X-ray staff, occurs dizziness headache, fatigue and weak, visual deterioration, once accepts Drug therapy, weak effect before 5 years.Inspection shows that under capsule, lamellar is muddy after bicrystal, sees cavity under left eye posterior lens capsule, and crystal transparency declines.Right vision is 0.6, and left vision is 0.5.Be diagnosed as radiational cataract.Take the present embodiment gained radiational cataract patient promoting blood circulation to remove obstruction in the collateral formulation tablet, every day three times, each 2, warm water takes.Take six weeks, patient's readme above-mentioned symptom alleviates to some extent, and vision takes a turn for the better.Continue to take two months, all diseases are eliminated, and vision restoration is normal.Follow-up observation is not recurred.
embodiment 4radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation, the primary raw material medicine getting following weight parts is prepared from (every part is 120g): take off the primary raw material medicine stating weight proportion and be prepared from: Radix Angelicae Sinensis 17 parts, Herba Violae 15 parts, Radix Polygalae 15 parts, Radix spiraeae japonicae 15 parts, Massa Medicata Fermentata 16 parts, Herba Thalictri Ramosi 18 parts, Radix Polygoni Multiflori 17 parts, Flos Cymbidii Ensifolii 18 parts, Herba saussureae nigrescentis 12 parts, Rhizoma Alismatis 20 parts, Semen Euryales 12 parts, Faeces Leporis 6 parts, 12 parts, Herba Ephedrae, Herba Amaranthi tricoloris 13 parts, Fructus Schisandrae Chinensis 16 parts, Folium Pleioblasti 12 parts.
The preparation method of above-mentioned radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation capsule is:
(1) put in pot by Pulvis Talci, talcous weight is 2/5 of Semen Euryales weight, and heating is with high heat stirred, and when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cools, and is ground into fine powder, crosses No. six sieves;
(2) add water in pot, amount of water is 13 times of Folium Pleioblasti weight, and put into Folium Pleioblasti after being heated to boil, remain micro-and boil 12 minutes, from fire, remove slag extracting juice;
(3) step (2) gained medicine juice is condensed into the thick paste that relative density is 1.34, dry at the temperature of 60 DEG C, dry 15 hours, be ground into fine powder, cross No. six sieves;
(4) all the other the 14 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(5) by step (1), step (3) and step (4) gained fine powder mix homogeneously, drying 12 hours at the temperature of 65 DEG C, spread out in stainless steel disc, thickness is 15-25mm, microwave sterilizating 4 minutes, loads zero capsule, every capsules is equipped with medicated powder 0.35g, by the capsule polishing in buffing machine installed, pressing plate, to obtain final product.
model case three:wu XX, man, 52 years old.Main suit: weak, visual deterioration, blurring of vision 8 years.Patient is steel mill workman, occurs weak, visual deterioration, blurring of vision before 8 years.Once treating at local hospital, poor effect, and introduced through friend, goes to a doctor in here of coming.Inspection shows that crystalline lens average thickness is 3.7mm, and crystalline lens is disk-like structure, puts lamellar muddiness after bicrystal under capsule.Right vision 0.7, left eye 0.8.Be diagnosed as radiational cataract.Take the present embodiment gained radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation capsule, every day three times, each 2, warm water takes.Take 2 first quarter moons, above-mentioned symptom obviously alleviates.Continue to take 2 months, symptom used all disappears, and vision restoration is normal.Follow-up observation has no recurrence.
embodiment 5radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation, the primary raw material medicine getting following weight parts is prepared from (every part is 120g): Radix Angelicae Sinensis 15 parts, Herba Violae 14 parts, Radix Polygalae 14 parts, Radix spiraeae japonicae 13 parts, Massa Medicata Fermentata 12 parts, Herba Thalictri Ramosi 17 parts, Radix Polygoni Multiflori 16 parts, Flos Cymbidii Ensifolii 16 parts, Herba saussureae nigrescentis 11 parts, Rhizoma Alismatis 18 parts, Semen Euryales 11 parts, Faeces Leporis 5 parts, 10 parts, Herba Ephedrae, Herba Amaranthi tricoloris 11 parts, Fructus Schisandrae Chinensis 15 parts, Folium Pleioblasti 11 parts.
The preparation method of above-mentioned radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation powder is:
(1) put in pot by Pulvis Talci, talcous weight is 2/5 of Semen Euryales weight, and heating is with high heat stirred, and when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cools, and is ground into fine powder, crosses No. seven sieves;
(2) add water in pot, amount of water is 13 times of Folium Pleioblasti weight, and put into Folium Pleioblasti after being heated to boil, remain micro-and boil 12 minutes, from fire, remove slag extracting juice;
(3) all the other the 14 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. seven sieves;
(4) step (1) and step (3) gained fine powder are fully mixed;
(5) step (2) gained medicine juice is condensed into the paste medicine that relative density is 1.36, adds 95% ethanol and gained paste medicine grinds altogether, then add the fine powder after step (4) mixing, grind well, in the vacuum drying oven of 50 DEG C, drying 24 hours, is distributed into and often wraps 5g, sterile packaged, to obtain final product.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Radix Angelicae Sinensis: base is former: be the dry root of umbelliferae angelica.The property of medicine: sweet, acrid, warm.Return liver, the heart, spleen channel.Function cures mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, traumatic injury, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, traumatic injury.
Herba Violae: base is former: be Violaceae Chinese violet, Herba Violae japonicae; The whole herb with root of leguminous plant Gueldenstaedtia verna, little Gueldenstaedtia verna or gentianaceae plant Gentiana.The property of medicine: bitter, cold. be included into the heart, Liver Channel.Function cures mainly: clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Control furuncle, carbuncle, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion, sore throat, venom.
Radix Polygalae: base is former: be the dry root of milk wort Radix Polygalae or ovum leaf Radix Polygalae.The property of medicine: bitter, pungent, temperature.GUIXIN, kidney, lung meridian.Function cures mainly: Fructus Alpiniae Oxyphyllae of calming the nerves, and eliminates the phlegm, detumescence.For the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.
Radix spiraeae japonicae: base is former: be the root of rosaceous plant pink blossom Ramulus et Folium Spiraeae Salicifolia, light leaf Ramulus et Folium Spiraeae Salicifolia.The property of medicine: bitter, pungent; Cool; Nontoxic.Return lung, Liver Channel.Function cures mainly: expelling wind and clearing away heat, improving acuity of vision and removing nebula.Main cough, headache, toothache, cataract.
Massa Medicata Fermentata: base is former: for the medicines such as Herba polygoni hydropiperis, Herba Artemisiae Annuae, Semen Armeniacae Amarum add flour or wheat bran mixed after, through the herbal leaven of fermentation.Chemical analysis: Massa Medicata Fermentata is yeast preparation, containing yeast, amylase, vitamin B complex, ergosterol, protein and fat, volatilization wet goods.The property of medicine: sweet; Pungent; Temperature; Nontoxic.Return spleen, stomach warp.Function cures mainly: invigorating the spleen and regulating the stomach, promoting digestion and removing stagnation.Main retention of food and drink, dyspepsia, distension and fullness in the abdomen, inappetence, vomiting dysentery.
Herba Thalictri Ramosi: base is former: be the herb of ranunculaceae plant racemosus Thalictrum aquilegifolium L. var. sibiricum Regel.The property of medicine: bitter in the mouth; Cold in nature.Return liver, large intestine channel.Function cures mainly: heat clearing and damp drying; Removing toxic substances.Cure mainly dysentery, jaundice, conjunctival congestion, carbuncle furuncle.
Radix Polygoni Multiflori: base is former: be the dried root of polygonum multiflorum thunb.The property of medicine: bitter, sweet, puckery, temperature.Return liver, heart kidney channel.Function cures mainly: removing toxic substances, disappears de-, loosening bowel to relieve constipation.For scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation, hyperlipidemia.
Flos Cymbidii Ensifolii: base is former: be the flower of orchid sword-leaved cymbidium.The property of medicine: pungent, flat.GUIXIN, spleen, lung meridian.Function cures mainly: regulate the flow of vital energy, alleviating distention in middle-JIAO, improving eyesight.For controlling chronic cough, uncomfortable in chest, diarrhoea, optic atrophy.
Herba saussureae nigrescentis: base is former: be the herb of the black purple hieracioides of feverfew.The property of medicine: acrid in the mouth; Bitter; Cool in nature.Function cures mainly: promoting blood flow to regulate menstruation, clearing away heat to improve acuity of vision.Main menoxenia, hectic fever due to YIN-deficiency consumptive fever, liver-heat conjunctival congestion.
Rhizoma Alismatis: base is former: be the dry tuber of Notes On Alism At Aceae Rhizoma Alismatis.The property of medicine: sweet, cold.Return kidney, urinary bladder channel.Function cures mainly: diuresis, clearing away damp-heat.For dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia.
Semen Euryales: base is former: be the mature seed kernel of nymphaeaceae plant Gorgon euryale.Chemical analysis: seed is containing volume starch.Containing 4.4 grams, protein in every 100 grams, 0.2 gram, fat, carbohydrate 32 grams, crude fibre 0.4 gram, ash 0.5 gram, calcium 9 milligrams, 110 milligrams, phosphorus, ferrum 0.4 milligram, thiamine 0.40 milligram, 0.08 milligram, riboflavin, nicotinic acid 2.5 milligrams, 6 milligrams, ascorbic acid, carotene trace.The property of medicine: sweet, puckery, flat.Return spleen, kidney channel.Function cures mainly: reinforcing the kindey to control nocturnal emission, spleen reinforcing stopping leak.Control seminal emission, stranguria with turbid discharge, leukorrhagia, incontinence of urine, loose stool and diarrhea.
Faeces Leporis: base is former: be the dry feces of the hares such as rabbit section animal Northeast Hare and south China rabbit.The property of medicine: acrid in the mouth; Cold in nature.Return liver, lung meridian.Function cures mainly: removing nebula improving eyesight, removing toxic substances parasite killing.Argument is raw nebula secretly, infantile malnutrition, hemorrhoid complicated by anal fistula.
Herba Ephedrae: the dry herb stem of Ephedraceae plant plait Herba Ephedrae, epheday intermedia or ephedra equisetina.The property of medicine: micro-hardship, pungent, temperature.Gui Jing: return lung, urinary bladder channel.Function cures mainly: diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.Cure mainly: for anemofrigid cold, uncomfortable in chestly to breath with cough, edema due to wind pathogen edema.Herba ephedrae nourishing the lung to arrest cough, is used for exterior syndrome and separates, asthma and cough.
Herba Amaranthi tricoloris: another name: Amaranthus mangostanus L., people Herba Amaranthi tricoloris, rising star Herba Amaranthi tricoloris, Herba amaranthi tricoloris, old and young year, ten sample brocades, an old person having a young heart' a person old in age but young in spirit, tampala, QINGXIANG Herba Amaranthi tricoloris, always become, Qiu Hong, be the stem and leaf of amaranthaceous plant Herba Amaranthi tricoloris.The property of medicine: sweet; Cold nature.Return large intestine, small intestine meridian.Function cures mainly: heat-clearing and toxic substances removing, smoothening secretion.Main dysentery, constipation and anuresis, snakeworm sting, sore.
Fructus Schisandrae Chinensis: base is former: be the dry mature fruit of magnoliaceae schisandra.The property of medicine: sour, sweet, temperature.Return lung, the heart, kidney channel.Function cures mainly: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
Folium Pleioblasti: base is former: be the tender leaf of grass bitter bamboo.The property of medicine: bitter; Cold.GUIXIN, Liver Channel.Function cures mainly: clear away heart-fire, diuresis improving eyesight, removing toxic substances.Main calentura excessive thirst, insomnia, oliguria with reddish urine, aphtha, ophthalmalgia, aphonia, burn and scald.
test example 1the clinical practice of gained radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation (embodiment 5) of the present invention: in June ,-2011 in January, 2006, screens 288 routine radiational cataract patients in 5 hospitals.Be divided into two groups at random, experimental group and matched group.Experimental group male 81 example, women 63 example, oldest 71 years old, minimum 40 years old of age, 54.8 years old mean age, course of disease 1-12, average course of disease 4.8 years.Matched group male 79 example, women 65 example, oldest 70 years old, minimum 38 years old of age, 54.5 years old mean age, course of disease 1-12, average course of disease 4.6 years.The physical data no significant difference such as two groups of case sexes, age, courses of disease, have comparability (P > 0.05).
Diagnostic criteria
The occupational history of ionizing radiation, dosage and cataractous Morphological Features is accepted according to person under inspection, by GBZ95-2002 " radiational cataract diagnostic criteria ", after getting rid of other cataract caused by Non-ionizing radiation factor such as traumatic, congenital, senile, make diagnosis.
Therapeutic Method
Experimental group uses gained radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation of the present invention, using method: every day twice, each 5g, and boiled water is taken after mixing it with water, and within 15 days, is a course for the treatment of.Matched group uses the medicine (as catalin, phacolin, catalin etc.) of conventional therapy radiational cataract, within 15 days, is a course for the treatment of.After two groups of patients all treat four courses for the treatment of, carry out Comparison of therapeutic.
The criterion of curative effect situation
Cure: clinical symptoms and sign disappear, patient's binocular vision recovers normal, without sense of discomfort, does not recur more; Take a turn for the better: clinical symptoms and sign take a turn for the better, and binocular vision increases, but does not recover completely; Invalid: disease is unchanged.Total effectively comprising cures and takes a turn for the better.After treating four courses for the treatment of, result is as shown in table 1.
Table 1: gained radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation compliance test result of the present invention
Efficacy analysis: after two groups of cases treat four courses for the treatment of, experimental group cures 90 examples, and take a turn for the better 51 examples, invalid 3 examples, total effective rate 97.92%; Matched group cures 45 examples, and take a turn for the better 63 examples, invalid 36 examples, total effective rate 75%.The cure rate of experimental group and total effective rate are apparently higher than matched group.The clinical efficacy of experimental group is obviously better than matched group, and significant difference (P < 0.05), has statistical significance.
The present invention, through scientific compatibility, selects the Chinese medicines such as Radix Angelicae Sinensis, Herba Violae, Radix Polygalae and Radix spiraeae japonicae to be primary raw material, makes radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation.In side, Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Herba Violae clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Radix Polygalae is calmed the nerves Fructus Alpiniae Oxyphyllae, eliminates the phlegm, detumescence.Radix spiraeae japonicae expelling wind and clearing away heat, improving acuity of vision and removing nebula.Massa Medicata Fermentata invigorating the spleen and regulating the stomach, promoting digestion and removing stagnation.Herba Thalictri Ramosi heat clearing and damp drying, removing toxic substances.Radix Polygoni Multiflori detoxifies, and disappears de-, loosening bowel to relieve constipation.Flos Cymbidii Ensifolii is regulated the flow of vital energy, alleviating distention in middle-JIAO, improving eyesight.Herba saussureae nigrescentis promoting blood flow to regulate menstruation, clearing away heat to improve acuity of vision.Rhizoma Alismatis diuresis, clearing away damp-heat.Semen Euryales reinforcing the kindey to control nocturnal emission, spleen reinforcing stopping leak.The improving eyesight of Faeces Leporis removing nebula, removing toxic substances parasite killing.Herba Ephedrae diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.Herba Amaranthi tricoloris heat-clearing and toxic substances removing, smoothening secretion.Fructus Schisandrae Chinensis convergence is astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.Folium Pleioblasti clears away heart-fire, diuresis improving eyesight, removing toxic substances.All medicines share, there is invigorating the spleen and regulating the stomach, spleen reinforcing reinforced the kidney, clear away heart-fire regulate the flow of vital energy, promoting blood circulation to remove obstruction in the collateral, tonify Qi of the kidney, the effect such as clearing away heat to improve acuity of vision, radiational cataract can be made to reach thorough healing, and treating both the principal and secondary aspects of a disease, not easily recur more.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation, is characterized in that, takes off the primary raw material medicine stating weight proportion and is prepared from: Radix Angelicae Sinensis 12-20, Herba Violae 11-16, Radix Polygalae 10-18, Radix spiraeae japonicae 10-18, Massa Medicata Fermentata 9-18, Herba Thalictri Ramosi 15-19, Radix Polygoni Multiflori 14-18, Flos Cymbidii Ensifolii 13-20, Herba saussureae nigrescentis 9-13, Rhizoma Alismatis 15-23, Semen Euryales 8-15, Faeces Leporis 4-7, Herba Ephedrae 7-13, Herba Amaranthi tricoloris 8-15, Fructus Schisandrae Chinensis 12-18, Folium Pleioblasti 9-13.
2. radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Angelicae Sinensis 14-17, Herba Violae 13-15, Radix Polygalae 13-15, Radix spiraeae japonicae 12-15, Massa Medicata Fermentata 11-16, Herba Thalictri Ramosi 16-18, Radix Polygoni Multiflori 15-17, Flos Cymbidii Ensifolii 14-18, Herba saussureae nigrescentis 10-12, Rhizoma Alismatis 17-20, Semen Euryales 9-12, Faeces Leporis 4.5-6, Herba Ephedrae 9-12, Herba Amaranthi tricoloris 10-13, Fructus Schisandrae Chinensis 14-16, Folium Pleioblasti 10-12.
3. radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Radix Angelicae Sinensis 15, Herba Violae 14, Radix Polygalae 14, Radix spiraeae japonicae 13, Massa Medicata Fermentata 12, Herba Thalictri Ramosi 17, Radix Polygoni Multiflori 16, Flos Cymbidii Ensifolii 16, Herba saussureae nigrescentis 11, Rhizoma Alismatis 18, Semen Euryales 11, Faeces Leporis 5, Herba Ephedrae 10, Herba Amaranthi tricoloris 11, Fructus Schisandrae Chinensis 15, Folium Pleioblasti 11.
4. the radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation as described in as arbitrary in claims 1 to 3, it is characterized in that, this radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation is made pharmaceutically acceptable powder, and the preparation method of described powder is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/3-3/5(preferably talc powder of Semen Euryales weight is 2/5 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. seven sieves;
(2) add water in pot, amount of water be the 9-14 of Folium Pleioblasti weight doubly (preferred amount of water is 13 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-8-15 of boiling minute (preferably maintaining micro-boiling 12 minutes), from fire, remove slag extracting juice;
(3) all the other the 14 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. seven sieves;
(4) step (1) and step (3) gained fine powder are fully mixed;
(5) step (2) gained medicine juice is condensed into the paste medicine (preferably step (2) gained medicine juice being condensed into the paste medicine that relative density is 1.36) that relative density is 1.33-1.37, add 95% ethanol and gained paste medicine grinds altogether, add the fine powder after step (4) mixing again, grind well, drying 24 hours in the vacuum drying oven of 50 DEG C, be distributed into and often wrap 5g, sterile packaged, to obtain final product.
5. the radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation as described in as arbitrary in claims 1 to 3, it is characterized in that, this radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation is made pharmaceutically acceptable pill, and the preparation method of described pill is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/3-3/5(preferably talc powder of Semen Euryales weight is 2/5 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. six sieves;
(2) add water in pot, amount of water be the 9-14 of Folium Pleioblasti weight doubly (preferred amount of water is 13 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-8-15 of boiling minute (preferably maintaining micro-boiling 12 minutes), from fire, remove slag extracting juice;
(3) all the other the 14 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) step (1) and step (3) gained fine powder are fully mixed, with the general ball of step (2) gained medicine juice, make the pill of the heavy 0.2g of every ball.
6. the radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation as described in as arbitrary in claims 1 to 3, it is characterized in that, this radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation is made pharmaceutically acceptable granule, and the preparation method of described granule is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/3-3/5(preferably talc powder of Semen Euryales weight is 2/5 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. six sieves;
(2) add water in pot, amount of water be the 9-14 of Folium Pleioblasti weight doubly (preferred amount of water is 13 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-8-15 of boiling minute (preferably maintaining micro-boiling 12 minutes), from fire, remove slag extracting juice;
(3) all the other the 14 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) by step (1) and step (3) gained fine powder mix homogeneously, fine powder after mix homogeneously and mass fraction be 16% starch slurry make altogether, make soft material, 14 mesh sieves are granulated, wet granular spreads out in enamel tray, to put in baking oven 60 DEG C and is dried to pellet moisture and controls about 4%, be more evenly sprayed at by step (2) gained medicine juice in dry granule, sealing placement 60 minutes, packs and get final product.
7. the radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation as described in as arbitrary in claims 1 to 3, it is characterized in that, this radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation is made pharmaceutically acceptable tablet, and the preparation method of described tablet is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/3-3/5(preferably talc powder of Semen Euryales weight is 2/5 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. six sieves;
(2) add water in pot, amount of water be the 9-14 of Folium Pleioblasti weight doubly (preferred amount of water is 13 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-8-15 of boiling minute (preferably maintaining micro-boiling 12 minutes), from fire, remove slag extracting juice;
(3) all the other the 14 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(4) by step (1) and step (3) gained fine powder mix homogeneously, fine powder after mix homogeneously and mass fraction be 14% starch slurry make altogether, make soft material, 14 mesh sieves are granulated, and wet granular spreads out in enamel tray, to put in baking oven 60 DEG C and are dried to pellet moisture and control about 4%, again step (2) gained medicine juice is evenly sprayed in dry granule, tabletting, the heavy 0.25g of every sheet, to obtain final product.
8. the radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation as described in as arbitrary in claims 1 to 3, it is characterized in that, this radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation is made pharmaceutically acceptable capsule, and the preparation method of described capsule is:
(1) Pulvis Talci is put in pot, talcous weight is the weight of the 1/3-3/5(preferably talc powder of Semen Euryales weight is 2/5 of Semen Euryales weight), heating is with high heat stirred, when frying to sliding sharp state, drop into Semen Euryales, constantly stir, fry to foresythia, take out, well sifted Pulvis Talci, cool, be ground into fine powder, cross No. six sieves;
(2) add water in pot, amount of water be the 9-14 of Folium Pleioblasti weight doubly (preferred amount of water is 13 times of Folium Pleioblasti weight), put into Folium Pleioblasti after being heated to boil, maintain micro-8-15 minute that boils, from fire, remove slag extracting juice;
(3) step (2) gained medicine juice is condensed into the thick paste (preferably step (2) gained medicine juice being condensed into the thick paste that relative density is 1.34) that relative density is 1.32-1.35, dry at the temperature of 55 DEG C-65 DEG C (preferably dry at the temperature of 60 DEG C), dry 12-28 hour (preferably dry 15 hours), be ground into fine powder, cross No. six sieves;
(4) all the other the 14 taste crude drug except Semen Euryales and Folium Pleioblasti are ground into fine powder respectively, cross No. six sieves;
(5) by step (1), step (3) and step (4) gained fine powder mix homogeneously, drying 12 hours at the temperature of 65 DEG C, spread out in stainless steel disc, thickness is 15-25mm, microwave sterilizating 3-6 minute, loads zero capsule, every capsules is equipped with medicated powder 0.35g, by the capsule polishing in buffing machine installed, pressing plate, to obtain final product.
9. the preparation method of radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation capsule as claimed in claim 8, is characterized in that, maintains micro-boiling 12 minutes in step (2).
10. the preparation method of radiational cataract patient promoting blood circulation to remove obstruction in the collateral preparation capsule as claimed in claim 8, is characterized in that, microwave sterilizating 4 minutes in step (5).
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| CN102784301A (en) * | 2012-07-18 | 2012-11-21 | 黄平县润发药业农民专业合作社 | Traditional Chinese medicine treating early cataract and its preparation method |
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Application publication date: 20150617 |