CN103520621A - Traditional Chinese medicine composition for treating senile cataract and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating senile cataract and preparation method thereof Download PDF

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CN103520621A
CN103520621A CN201310509764.9A CN201310509764A CN103520621A CN 103520621 A CN103520621 A CN 103520621A CN 201310509764 A CN201310509764 A CN 201310509764A CN 103520621 A CN103520621 A CN 103520621A
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李佃场
梁轶聪
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Zeng Qingyun
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Abstract

The invention discloses a traditional Chinese medicine composition for treating senile cataract. The traditional Chinese medicine composition is prepared from the following active pharmaceutical ingredients: peach kernels, safflower, Chinese angelica, Szechwan lovage rhizome, prepared rhizome of adhesive rehmannia, white paeony root, tribulus terrestris, cassia occidentalis, medlar, medicated leaven, salvia miltiorrhiza, fructus alpiniae oxyphyllae, fructus mori, glossy privet fruit, chrysanthemum, Chinese yam, seaweeds, fructus schisandrae, endothelium corneum gigeriae galli, tangerine peel, magnetite, feather cockscomb seed, purple bergenia herb, concha mauritiae, pipewort and bat dung. The composition has the functions of soothing the liver and strengthening the spleen, clearing pores, softening hardness to dissipate stagnation or promoting blood circulation to remove blood, resolving fatigues and dredging joints and orifices and improving microcirculation, is used for treating various senile cataract, has simple preparation processes and small toxic and side effects, is convenient to administrate, is easy to prepare, is low in cost, can directly treat focuses, ensures short cure time and avoids relapse after cure.

Description

A kind of Chinese medicine composition for the treatment of senile cataract and preparation method thereof
 
Technical field
The present invention relates to contain the medicinal preparation that derives from plant, animal or raw mineral materials, particularly a kind of Chinese medicine composition for the treatment of senile cataract and preparation method thereof.
 
Background technology
Senile cataract is modal cataract, and after being more common in 50 years old, sickness rate increases with the growth at age.Senile cataract is the degenerative change engendering in crystalline lens ageing process, and mechanism also imperfectly understands.Generally be divided into cortex, nuclearity and three kinds of multiple colonies of capsule mo(u)ld bottom half and be more common in 50 years old above middle-aged and elderly people, with the age, increase its sickness rate and raise.Disease symptoms: with oculogyral shade at the moment, gradual Silent Neuritis visual deterioration, monocular diplopia or look more, iridization, photophobia and dazzle.Eyes are ill, have successively, and the order of severity differs.
Names of disease of tcm there is no cataractous name, is mainly cataract, sees " Long Mu's Secret Treatise on Ophthalmology ".Refer to the muddy pathological changes of Rhizoma Polygonati (crystalline lens).Cataract quite up to the present.Successive dynasties doctors nationality is because of its cause of disease, shape, color, and degree is different and have many titles, as: fetal toxicosis cataract, incipient cataract, complicated cataract, as silver barrier, cataract etc.Its Symptoms is: in just suffering from, common fly flyings are sent out at the moment, hang down and play, and Haze mist, increases the weight of gradually, superficial, gradually blind.Outward appearance no abnormality seen, does not distinguish personage, only sees three light.Thoroughly see that, in pupil, Rhizoma Polygonati is the muddiness of different shape and colors, Se Bai or micro-Huang, or pale blue, shape as star, as Flos Jujubae, as first quarter moon, as sword ridge, as the walking of hydrargyrum, as the liquid of cream fat, as in the dripping of oil, freezing in cup as ice.Can a lore suffer from, also have eyes with sick.Duo Xia is worn with age, both liver and kidney deficiency, asthenia of essence and blood, or insufficiency of the spleen mistake fortune, vital essence can not sending nutrient upward to eye or the congestion that causes thus due to.In addition, stagnated heat of liver channel or the deficiency of YIN are held under the arm on damp and hot and are attacked, and also can cause primary disease.Clinical diagnosis: cataract from the beginning of, eye, without congestion and swelling pain, is only consciously looked micro-dusk of thing, or has the fixing point-like in position, strip or discoid shade at the moment; Or look closely still clear, dim depending on dusk far away; Or Shi Hun, dark place, daylight is looked clearly; Or dusk is looked in Shi Qing, dark place, daylight; Or look light, bright moon if any several.Dim day of dusk entered, and, gradually to not distinguishing personage, only saw manually, even only deposited light sensation.Inspect pupil god, rounding is intact, and companding freely.From the beginning of, if brilliant pearl muddiness comes across edge, shape is as Flos Jujubae, sawtooth, vision has no significant effect more.The greyish white swelling of brilliant pearl that continues, as oils and fats is bubbled through the water column, torch side photograph, the shade of visible yellow core is the crescent brilliant bead surface that is projeced into.Final mature cataract, the white rounding of color, torch side photograph, yellow core shade disappears.Now nebula hinders always surely, just should operative treatment.Otherwise with the passing of time brilliant pearl dwindles, nebula like icicle and sinking.If brilliant pearl muddiness, from core, gradually spreads towards periphery, its color mostly is pale brown, reddish brown or black.Therapeutic Principle: primary disease treatment, soothing liver and strengthening spleen, tonneau Xuan Fu, hard masses softening and resolving, blood circulation promoting and blood stasis dispelling, coordinates the method treatments such as acupuncture, laser, external treatment.
Modern medicine thinks, the senile cataract cause of disease is comparatively complicated, may be the results of many factors to crystalline lens comprehensive and long-term action such as environment, nutrition, metabolism and heredity.It is generally acknowledged that Oxidation is to cause cataractous earliest period to change.Ultraviolet radiation too much, drinking too much, smoking is many, women 's fertility is many, cardiovascular disease, hypertension, psychosis, body wound etc. are relevant with cataractous formation.Pathogenesis: it is generally acknowledged, radical damage is to cause the various common pathways that cause the effect of cataract factor, lens epithelial cells excessive Apoptosis and crystallin damage are also the key factors in cataract mechanism.In senile cataract forming process, mainly there are two kinds of pathological changes.The first, the imbalance of cortex of lens water-electrolyte balance, causes moisture in crystalline lens to be assembled, and causes lens fibers edema, liquefaction.The second, the albuminous degeneration of nucleus lentis, swelling.These changes cause the lens fibers structure of proper alignment to get muddled.
In treatment, take 1 more, Drug therapy: there is no at present the sure medicine of curative effect and be used for the treatment of cataract.Some early cataracts, the sick lazy development of may slowing down after medication, vision also slightly improves, but this is the result of Drug therapy not necessarily, because cataractous, advancing in early days maturation is a veryer long process, and it likely naturally stops at a certain developmental stage and is unlikely to have a strong impact on vision.Some in mid-term cataract patient, after medication, vision and lenticular opacity degree are not all improved.The cataract in nearly period of maturation, Drug therapy is more without practical significance.At present not lower tens kinds of conventional medicine clinically, has collyrium or oral Chinese medicine and western medicine, but all there is no definite therapeutic effect.2, operative treatment: during because of cataract affected work and daily life, can consider operative treatment.Cataract operation mainly comprises at present: intracapsular extraction of cataract, extracapsular extraction of cataract+intraocular lens implants, cataract phacoemulsification art+intraocular lens implants, laser emulsifying Cataract+intraocular lens implants, the most frequently used modus operandi is cataract phacoemulsification art+intraocular lens implants.After extractio intracapsularis, patient can join frame eyeglasses or corneal contact lens by testing, or improves vision by cornea refractive surgery.
 
Summary of the invention
Technical problem to be solved by this invention is, provides that a kind of formula is simple, processing technology is easy, the little and convenient drug administration of toxic and side effects, and medicament is easy to manufacture, new drug with low cost.The present invention adopts the Chinese crude drug of different properties, has carried out science compatibility, can reach desirable therapeutic effect, and safety, and toxic and side effects is little, and preparation is simple, the focus of going directly, and healing time is short, after curing, is difficult for recurrence.
For solving the problems of the technologies described above, the invention provides a kind of Chinese medicine composition for the treatment of senile cataract, in described Chinese medicine composition, the ratio of weight and number of various crude drug is: 10~25 parts, Semen Persicae, 10~25 parts, Flos Carthami, 10~25 parts of Radix Angelicae Sinensis, 10~25 parts of Rhizoma Chuanxiongs, 10~25 parts, Radix Rehmanniae Preparata, 10~25 parts of the Radix Paeoniae Albas, 10~20 parts of Fructus Atriplicis Sibiricaees, 10~20 parts of Semen Cassiae, 10~25 parts of Fructus Lyciis, 10~25 parts of Massa Medicata Fermentata, 10~25 parts of Radix Salviae Miltiorrhizaes, 10~25 parts of Fructus Alpiniae Oxyphyllae, 10~25 parts of Fructus Mori, 10~25 parts of Fructus Ligustri Lucidi, 10~20 parts of Flos Chrysanthemis, 10~20 parts of Rhizoma Dioscoreaes, 10~20 parts of Sargassums, 10~25 parts of Fructus Schisandrae Chinensis, 10~20 parts of Endothelium Corneum Gigeriae Galli, 10~25 parts of Pericarpium Citri Reticulataes, 10~30 parts of Magnetitums, 10~20 parts of Semen Celosiae, 10~20 parts of Rhizoma Seu Herba Bergeniaes, 10~20 parts, shellfish tooth, 10~20 parts of 10~20 parts of Flos Eriocaulis and Faeces Vespertilioniss.
The Chinese medicine composition of described treatment senile cataract, the ratio of weight and number of various crude drug can also be: 10~25 parts, Semen Persicae, 15~25 parts, Flos Carthami, 10~25 parts of Radix Angelicae Sinensis, 20~25 parts of Rhizoma Chuanxiongs, 15~25 parts, Radix Rehmanniae Preparata, 10~25 parts of the Radix Paeoniae Albas, 10~20 parts of Fructus Atriplicis Sibiricaees, 10~20 parts of Semen Cassiae, 20~25 parts of Fructus Lyciis, 20~25 parts of Massa Medicata Fermentata, 10~25 parts of Radix Salviae Miltiorrhizaes, 10~15 parts of Fructus Alpiniae Oxyphyllae, 10~20 parts of Fructus Mori, 10~20 parts of Fructus Ligustri Lucidi, 10~20 parts of Flos Chrysanthemis, 10~15 parts of Rhizoma Dioscoreaes, 10~15 parts of Sargassums, 10~20 parts of Fructus Schisandrae Chinensis, 10~15 parts of Endothelium Corneum Gigeriae Galli, 10~15 parts of Pericarpium Citri Reticulataes, 10~20 parts of Magnetitums, 15~20 parts of Semen Celosiae, 10~20 parts of Rhizoma Seu Herba Bergeniaes, 10~20 parts, shellfish tooth, 10~20 parts of 10~15 parts of Flos Eriocaulis and Faeces Vespertilioniss.
The Chinese medicine composition of described treatment senile cataract, the ratio of weight and number of various crude drug can be also: 10~20 parts, Semen Persicae, 10~15 parts, Flos Carthami, 10~20 parts of Radix Angelicae Sinensis, 10~20 parts of Rhizoma Chuanxiongs, 10~20 parts, Radix Rehmanniae Preparata, 10~15 parts of the Radix Paeoniae Albas, 10~15 parts of Fructus Atriplicis Sibiricaees, 10~15 parts of Semen Cassiae, 10~20 parts of Fructus Lyciis, 10~20 parts of Massa Medicata Fermentata, 10~20 parts of Radix Salviae Miltiorrhizaes, 10~25 parts of Fructus Alpiniae Oxyphyllae, 20~25 parts of Fructus Mori, 10~25 parts of Fructus Ligustri Lucidi, 10~15 parts of Flos Chrysanthemis, 10~20 parts of Rhizoma Dioscoreaes, 10~20 parts of Sargassums, 20~25 parts of Fructus Schisandrae Chinensis, 15~20 parts of Endothelium Corneum Gigeriae Galli, 15~25 parts of Pericarpium Citri Reticulataes, 20~30 parts of Magnetitums, 10~20 parts of Semen Celosiae, 10~15 parts of Rhizoma Seu Herba Bergeniaes, 10~15 parts, shellfish tooth, 10~15 parts of 10~20 parts of Flos Eriocaulis and Faeces Vespertilioniss.
For solving the problems of the technologies described above, the present invention also provides a kind of preparation method for the treatment of the Chinese medicine composition of senile cataract, the dosage form of described Chinese medicine composition is cold compress agent, described preparation process is: first the described crude drug except Borneolum Syntheticum is ground into coarse powder, further pulverize again, cross 120 mesh sieves, the fine powder of collecting by 120 mesh sieves obtains fine powder a; Can not by the coarse powder of 120 mesh sieves, drop into multi-function extractor again and extract twice, and add for the first time 4-6 times of water gaging and decoct 1-2 hour, and add for the second time 3-5 times of water gaging and decoct 1-2 hour, merge decocting liquid twice, filter to get filtrate; Filtrate heating is concentrated into pasty state, puts into after 80 ℃ of oven dry of baking oven coolingly, grind to form fine powder b, fine powder a is mixed standby afterwards with fine powder b; Then by Borneolum Syntheticum extraction by steam distillation, obtain crystal c; Crystal c is added in the mixture of fine powder a and fine powder b, mix add appropriate glycerol, glycerol addition be fine powder mixture gross mass 2-8 doubly, furnishing paste, packs into after sterilization in colored bottle, puts into 0 ℃ of-4 ℃ of storage of refrigerator-freezer standby.
For solving the problems of the technologies described above, the present invention also provides a kind of preparation method for the treatment of the Chinese medicine composition of senile cataract, and the dosage form of described Chinese medicine composition is eye drop, and described preparation process is:
A, get described crude drug and add water extraction 2 times, add for the first time 4-6 times of water gaging and decoct 1-2 hour, add for the second time 3-5 times of water gaging and decoct 1-2 hour, 2 extracting solution are merged, filter, the extractum 1 that when concentrating under reduced pressure obtains 80 ℃, relative density is 1.04~1.10, medicinal residues are standby;
B, medicinal residues are added to 60-90% soak with ethanol 0.5-1.5 hour, extract twice, each 1-2 hour, merge extractive liquid,, filters, concentrated, 80-160 order filters, and 6000-10000 rev/min centrifugal, gets supernatant, through the molecular weight that dams, be the ultrafiltration post ultrafiltration of 5000-10000,1.25 extractum 2 when ultrafiltrate concentrating under reduced pressure relative density is 60 ℃;
C, extractum 1 and extractum 2 is mixed, add 0.06% sodium chloride and the 60-80 distilled water doubly that mix extractum gross mass, and to add concentration be that to regulate PH be 6.0-7.0 to 4% sodium hydroxide solution, add again 0.2% active carbon to boil 10 minutes, filter packing, sterilizing, obtains eye drop.
For solving the problems of the technologies described above, the present invention provides a kind of dosage form for the treatment of the Chinese medicine composition of senile cataract again, and pharmaceutical dosage form is: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, suck agent, granule, electuary, honey pill agent, powder, sublimed preparation, solution, injection, suppository, plaster, syrup, powder or spray.
Described Chinese medicine composition, medicine is decocted in use decoction and is taken, and 1 dose of every day, decocting takes at twice, and every 7 days is a course for the treatment of; When this Chinese medicine composition is pill, capsule or tablet while using, three times on the one, every 7 days is a course for the treatment of.
Chinese medicine composition of the present invention has soothing liver and strengthening spleen, tonneau Xuan Fu, and hard masses softening and resolving, or blood circulation promoting and blood stasis dispelling, change tired sensiblely, improves microcirculation, is used for the treatment of various senile cataract symptoms; And processing technology is easy, the little and convenient drug administration of toxic and side effects, medicament is easy to manufacture, new drug with low cost.The present invention is Chinese medicine composition, but the gentle Chinese medicine of selected abnormal smells from the patient makes the abnormal smells from the patient of Chinese medicine composition also light, adopts the therapies such as cold compress can greatly alleviate patient's discomfort.The present invention adopts the Chinese crude drug of different properties, has carried out science compatibility, can reach desirable therapeutic effect, and safety, and toxic and side effects is little, and preparation is simple, the focus of going directly, and healing time is short, after curing, is difficult for recurrence.
 
The specific embodiment
The traditional Chinese medical science thinks that primary disease is by worn with age, or natural endowment is not enough, or the reason such as wound, violence causes, its pathogenesis mainly contains with below: the hepatic and renal YIN deficiency: liver opening at eye, and order obtains liver blood and can look, and pupil god belongs to kidney for water wheels, and kidney essense abundance is wonderful light.If asthenia with age, vital essence is not filled, or because working with one's mind too much, cloudy blood specially dissipates, or natural endowment is not enough, can cause deficiency of liver-blood, deficiency of the yin of the liver and deficiency of kidney-essence, and The liver and the kidney have a common source, and essence and blood alternate, therefore the hepatic and renal YIN deficiency often exists simultaneously.Asthenia of essence and blood, Liver and kidney two void, brilliant pearl is lost to support and forms cataract.Deficiency of spleen-QI and stomach-QI: old, deficiency of spleen-QI and stomach-QI, transporting mistake department, QI and blood is biochemical deficient, and eyes losing nutrition, causes the generation of primary disease, and dysfunction of the spleen in transportation, and ascending or descending movement of vital Qi is not normal, clear QI failing to ascend, turbid QI failing to descend, also can cause primary disease.The all few moving how quiet body of old people, blood fortune therefore and slowly sluggish, for a long time and formation blood stasis.Again because of wound, violence, the frightened shake of brilliant pearl, qi depression to blood stasis, invade and harass refreshing water and gradually muddiness bleach.
External therapy of tcm is one of the most frequently used clinically external treatment of Chinese medicine, " Handbook of Prescriptions for Emergencies " of Jin Daige flood work, the Thousand Golden Prescriptions of the Tang Dynasty Sun Simiao, supplement to Thousand Golden Prescriptions, in " medical secrets of official " of Wang Taozhu and the Compendium of Material Medica of Ming Dynasty's Li Shizhen (1518-1593 A.D.), contained therapy has all related to external therapy of tcm.Because meridians have interior genus internal organs, outer network podomere, link up the exterior and the interior, run through upper and lower effect, thus not only can treat local patholoic change, but also can reach by external application the object for the treatment of systemic disease.Medicine, by the stimulation at local acupuncture point, penetrates through skin, excites through feeling pulse gas, promotes internal organs QI-blood circulation, plays therapeutical effect; Avoided oral simultaneously and injected bring inconvenient and painful, the head of a family and infant are easy to accept, and lasting medicine, have avoided the first pass effect of liver and interference and the Degradation of gastrointestinal factor, reduce individual variation, rapid-action, strong drug action, without wound, no pain, easy to use.
Semen Persicae in side, Flos Carthami, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae can blood circulation promoting and blood stasis dispelling, coordinate the Sargassum can hard masses softening and resolving.Radix Rehmanniae Preparata, the Radix Paeoniae Alba can be nourished blood.Fructus Mori, Fructus Ligustri Lucidi, Fructus Schisandrae Chinensis, Fructus Lycii, Rhizoma Dioscoreae can nourishing kidney-YINs, and having can spleen invigorating, convergence.Four share can tonification healthy energy.Flos Eriocauli can nourishing kidney-yin, auxiliary upper four Chinese medicine thing.Flos Chrysanthemi, Pericarpium Citri Reticulatae can depressed liver-energy dispersing and QI regulating, regulate the operation of the gas of the whole body.Endothelium Corneum Gigeriae Galli can controlling nocturnal emission with astringent drugs.Coordinate the convergence of Magnetitum controlling nocturnal emission with astringent drugs, and can calm the nerves.Fructus Atriplicis Sibiricae, suppressing the hyperactive liver resolving depression, dispelling pathogenic wind for improving eyesight.Semen Cassiae, clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.Massa Medicata Fermentata, invigorating the spleen and regulating the stomach; Promoting digestion and removing stagnation.Fructus Alpiniae Oxyphyllae, temperature compensation astringency inducing, warm spleen antidiarrheal, Semen Celosiae, liver heat removing, improving eyesight, nebula removing.Flos Eriocauli, wind and heat eliminating, improving acuity of vision and removing nebula.Rhizoma Seu Herba Bergeniae, the kidney invigorating; Improving eyesight; Shellfish tooth, clearing away heart-fire for tranquillization, suppressing the hyperactive liver improving eyesight; Faeces Vespertilionis, optic atrohic blindness; Nyctalopia; Conjunctival congestion and swelling pain; Subconjuctival hemorrhage.
Semen Persicae, bitter, sweet, flat.GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.For amenorrhea, dysmenorrhea , WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.Semen Persicae bitter but sweet flavor and property are flat, can enter the heart, liver, large intestine, and blood circulation promoting and blood stasis dispelling effect is very wide, availablely control the various worn-out diseases of stagnation of blood stasis.Aspect treatment, be good at treating abscess of internal organ, as lung abscess; Acute appendicitis is often held as wanting key medicine, is the peculiar performance Yu of its tool.The many matter of fat profit, the merit of tool loosening bowel to relieve constipation, only in recent years clinical specially with loosening bowel to relieve constipation less use.Menorrhagia and contraindication in pregnancy.Semen Persicae and Flos Carthami are all the medicine of blood circulation promoting and blood stasis dispelling, act on all very extensive, fit applications often, only Semen Persicae is kind controls lung abscess acute appendicitis, and has the effect of loosening bowel to relieve constipation; Flos Carthami is good at promoting blood flow to regulate menstruation.Relieving constipation: cellulose can promote the wriggling of intestinal wall, helps digest, prevents from being hard and dry.Can lubricate intestinal, stimulate defecation.Keep enteral feces moistening, in order to relieving constipation.Vitamin B group can be secreted by facilitating digestion liquid, maintains and promote to be conducive to defecation by intestinal peristalsis promoting.Regulating menstruation: relieving dysmenorrhea, or lumbago in menstrual period.Conditioning menstrual period long (short) or hypomenorrhea (many).Hemostasis: contain a large amount of colloids, generate platelet, have hemostasia effect.The patient of suitable hemorrhage.Suitable menorrhagia, the women of metrorrhagia.Makeup energy: carbohydrate containing, saccharide, can be rapidly for health provides energy.
Flos Carthami, warm in nature, acrid in the mouth, promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury.When ancients often have what blood in vivo, often add Flos Carthami tate.Bundle is boiled available one day twice foot bath, applicable various varicosis, and peripheral neuritis, blood circulation is bad, lower limb numbness or the congestion such as livid purple.Irregular menstruation, puerperal abdonimal pain, lump in the abdomen, the disease such as traumatic stasis swells and ache, ulcer sore pain.Come from " Bencao Tujing ": " red blue flower, Flos Carthami also.The present has it everywhere.Other ground threshing is planted, and winter and cloth is in Radix Rehmanniae Preparata, to raw Seedling of spring, and Xia Naiyou flower, the lower Qiu that does converges, thorniness, it is upper that pistil goes out Qiu, and people from garden holds to reveal and adopts it, adopts and appears again, to stopping to the greatest extent.Solid in Qiu, white, as large in Semen Phaseoli.It spends suddenly and violently dry very red to dye, and makes swallow fat.After main product, disorders of blood is victory.In fact also same.Leaf is quite like blue, therefore there is blue name.”
Radix Angelicae Sinensis,, the dry root that these product are umbelliferae angelica.Autumn end excavates, and removes fibrous root and silt, after moisture slightly evaporates, is bundled into wisp, and upper canopy, with pyrotechnics smoke-dried beancurd slowly.Radix Angelicae Sinensis root is slightly cylindrical, and root upper end claims " returning head ", and main root claims " returning body " or " very little body ".Supporting root claims " Radix Angelicae Sinensis " or " returning lower limb ", all claim " Radix Angelicae Sinensis ".Radix Angelicae Sinensis can be enriched blood, can invigorate blood circulation again, and general designation and blood; Radix Angelicae Sinensis body is enriched blood, Radix Angelicae Sinensis removing blood stasis sweet in the mouth; Pungent; Bitter; Warm in nature.Return liver; The heart; Spleen channel.Hematonic; Emmenagogue; Analgesic.Enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.The all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.
Rhizoma Chuanxiong, blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping.Textual criticism: come from Materia Medica of Decoction and cure mainly: medicine first choice for the treatment of headache.Menoxenia; Amenorrhea dysmenorrhea; The stagnant raw meat pain of the stasis of blood in puerperal; Lump in the abdomen lump; Pain in chest and hypochondrium; Have a headache dizzy; Anemofrigid-damp arthralgia; Traumatic injury; Ulcer sores." herbal classic ": main apoplexy enters brain headache, arthralgia due to cold, clonic spasm of the muscle emergency, gold wound, married woman's blood closes loss of fecundity." not Lu ": except cold moving in brain, on face, urticaria goes, order lacrimation, profuse nasal discharge and spittle, before we notice it as liquor-saturated, all cold gas, the hard pain of trusted subordinate, attacked by pestiferous factors, soldier is anxious to swell and ache, side of body wind pain, warming middle-JIAO endogenous cold.TAO Hong-Jing: tooth root bleeder, is recovered more than containing." property of medicine opinion ": control waist foot weak, hemiplegia, main afterbirth does not go out, and controls cold type of pain in abdomen." Japan hanako materia medica ": control a wind cutting, all gas, all strains, all blood, mend five kinds of over strain, and strengthening bone and muscle, adjusts many arteries and veins, and broken crux stagnated blood, supports fresh blood, puts on flesh, and serious epistaxis, spits blood and hematuria, hemorrhoid complicated by anal fistula, brain carbuncle carbuncle on the back, scrofula wart is superfluous, skin ulcer scabies, and evacuation of pus repercussive blood." medicine origin ": enrich blood, control headache due to deficiency of blood.Wang Haogu: search irritability, tonifying liver blood, profit liver is dry, mends wind empty." detailed outline ": dampness, antidiarrheal dysentery, activating QI to alleviate the depression.Rhizome of chuanxiong Qiong, in blood gas medicine also, liver bitter anxious with pungent benefit it, therefore blood deficiency person should it; Pungent to fall apart it, therefore stagnation of QI person should it." left biography " sayed wheat Qu, brought up poor imperial wetting, and controls stomach ailment.Give and control dairrhea caused by pathogenic damp, often add two tastes, it should be as sound.Dysentery is led to and the more than person of pain, is the cloudy stagnation of QI of losing, and in medicine, adding rhizome of chuanxiong is assistant, and gas promoting the circulation of blood is adjusted, and its disease stops immediately.Amplification on Canon of Materia Medica: rhizome of chuanxiong Qiong, moderns are used at most, women's head-ornaments wind can not fault also, so must help it with his medicine.
Radix Rehmanniae Preparata, the yin nourishing of enriching blood, life essence-filling, marrow-benefitting.Apply all cards of 1. blood deficiency.The sweet Wen Zhirun of this product, nourishing YIN benefit essence, with hemopoietic, is the key medicine of the tonify deficiency that nourishes blood.Normal and Radix Angelicae Sinensis, the Radix Paeoniae Alba, the same use of Rhizoma Chuanxiong, treat blood deficiency and yellow complexion, dizzy, cardiopalmus, insomnia and menoxenia, metrorrhagia and metrostaxis etc., as SIWU TANG); If deficiency of heart-blood severe palpitation, can be with the sedative such as Radix Polygalae, Semen Ziziphi Spinosae with using; If the empty cold in blood of metrostaxis and hyperamization, few abdomen cold type of pain person, can with tonifying blood and arresting bleeding, the same use of dispelling cold by warming the meridian medicine such as Colla Corii Asini, Folium Artemisiae Argyi, as Ass-hide Glue and Argyi Leaf Decoction.2. all cards of the hepatic and renal YIN deficiency.This quality is moistened into kidney, kind nourishing kidney yin, and life essence-filling, marrow-benefitting, is the key medicine of tonifying kidney-yin.Ancients call it " large tonifying five ZANG-organs is Kidney-Yin ", " mending greatly true water ".Normal be equal to use with Rhizoma Dioscoreae, Fructus Corni, treat the hepatic and renal YIN deficiency, soreness of the waist and knees, seminal emission, night sweat, tinnitus, deafness and quench one's thirst etc., can invigorating the liver and kidney, and beneficial marrow, as LIUWEI DIHUANG WAN; Also can be equal to treatment deficiency of YIN osteopyrexia and fever, as dabuyin pill (" danxi's experiential therapy ") with the Rhizoma Anemarrhenae, Cortex Phellodendri, Carapax Et Plastrum Testudinis.This product benefiting essence-blood, black beard and hair, the compatibilities such as normal and Radix Polygoni Multiflori, Radix Achyranthis Bidentatae, Semen Cuscutae, control blood and essence asthenia early whitening of beard and hair, as Qibao Meiran Dan (" collection of prescriptions with notes "); This product vital essence replenishing and marrow benifiting, bone and muscle strengthening, also can join Carapax Et Plastrum Testudinis, Herba Cynomorii, Rhizoma Cibotii etc., treatment deficiency of the liver and kindey, and five kinds of growth retardation five kinds of flaccidity in infant, as Huqian Wan (" collection of prescriptions with notes ").In addition, Radix Rehmanniae Preparata charcoal can stop blooding, and can be used for the blood deficiency such as metrorrhagia and goes out blood disorder.
The Radix Paeoniae Alba, cool in nature, bitter in the mouth acid, is slightly cold, and has the easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving.Yin fluid astringing is received the effects such as antiperspirant, is applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction anxious, dysentery stomachache, spontaneous sweating, metrorrhagia, is with inferior disease.That paeoniflorin has is antibiotic, analgesic, antiinflammatory, increase coronary flow, improve the effect of myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjusting blood glucose.Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc.
Fructus Atriplicis Sibiricae, suppressing the hyperactive liver resolving depression, dispelling pathogenic wind for improving eyesight.For dizziness due to hyperactivity of liver-YANG headache, hypochondriac pain due to stagnation of liverQI, headache due to pathogenic wind-heat, conjunctival congestion and swelling pain, the diseases such as skin pruritus.Tribulus terrestris, has nature to promote testosterone, increases strength, improves whole competitive state, has no side effect.
Fructus Schisandrae Chinensis is as medical material, record the earliest in Shennong's Herbal, be listed in top grade.Ancients once evaluated like this Fructus Schisandrae Chinensis " the sweet acid of Fructus Schisandrae Chinensis skin and flesh, core first are arduous, have saline taste this five tastes are all also." be perhaps the origin of its name, Fructus Schisandrae Chinensis is warm in nature.Modern pharmacological research shows, Radix Schisandrae Bicoloris contains multiple nutritional components, as schizandrin, malic acid, citric acid, tartaric acid, succinic acid, fatty oil, volatile oil, saccharide, resin, vitamin C etc., also contain the trace element such as tungsten, ferrum, manganese, zinc, phosphorus.Fructus Schisandrae Chinensis also has the effect of the pathogenic microorganism such as certain anti-bacteria breeding, Fructus Schisandrae Chinensis water decoction to tubercule bacillus, bacillus subtilis, escherichia coli, Bacillus typhi, staphylococcus aureus, streptococcus, Diplococcus pneumoniae, have stronger inhibitory action.Utilize clinically the effect of its astringent therapy, be used for astringing the lung, hidroschesis, arresting seminal emission antidiarrheal etc.
Rhizoma Dioscoreae sweet in the mouth, property are put down, and enter lung, spleen, kidney channel; Not dry oiliness, there are strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, the benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, grow that will is calmed the nerves, the effect of life lengthening; Cure mainly that weakness of the spleen and stomach, lassitude, inappetence, chronic diarrhea and dysentery, insufficiency of lung-QI are dry, phlegm dyspnea cough, kidney qi loss, soreness of the waist and knees, lower limb flaccidity are weak, the red disease such as swollen, fat of the frequent micturition of quenching one's thirst, seminal emission premature ejaculation, leukorrhagia nebulousurine, skin.Compendium of Material Medica is summarized five large functions " kidney tonifying gas, strengthening the spleen and stomach, stopping leak dysentery, the saliva that reduces phlegm, profit skin ".Rhizoma Dioscoreae is cooked congee or simmers after ripe and take with crystal sugar, and, colitis poor to health, deficiency of the kidney chronic diseases are all effective in cure.Strengthen the spleen and stomach: treatment weakness of the spleen and stomach, have loose bowels, body is tired, lack of appetite, sweating due to debility.Lung benefiting nourishing kidney: this product is cold not dry, sweet in the mouth matter profit, can treat lung suffer from a deficiency of the kidney damage quench one's thirst, pass out semen, be with inferior disease, be described as angle's medicine.
Pericarpium Citri Reticulatae temperature; Pungent, bitter; Returning the bitter substance of spleen, lung meridian Pericarpium Citri Reticulatae to take limonin and bitter principle is representative " limonoid ", and this limonoid taste is gentle, soluble in water, contributes to the digestion of food.When Pericarpium Citri Reticulatae is used for cooking dishes.Its bitterness and other tastes are in harmonious proportion mutually, can form original in style local flavor.Pericarpium Citri Reticulatae contains the compositions such as volatile oil, hesperidin, vitamin B, C, and its contained volatile oil has gentle stimulation to gastrointestinal tract, and pneumatosis in intestinal tube is got rid of in secretion that can facilitating digestion liquid, increases appetite.Pericarpium Citri Reticulatae is also conventional Chinese medicine simply, has the greasy lasting of spleen invigorating, drying dampness to eliminate phlegm, solution of ventilation, the effect of stopping nausea and vomiting by lowering the adverse flow of QI.
Semen Cassiae, clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.For the puckery pain of conjunctival congestion, the many tear of photophobia, has a headache dizzy, poor vision, constipation.Return liver, kidney, large intestine channel.The effect that has fat-reducing.Control wind heat acute conjunctivitis, optic atrohic blindness, nyctalopia, hypertension, hepatitis, cirrhotic ascites, habitual constipation.1. TAO Hong-Jing: Semen Cassiae, leaf is as Semen Cassiae Sopherae, and son likeness in form Horse hoof, exhales as Horse hoof Semen Cassiae.With when smashing to pieces.Not having Semen Cassiae again, is luxuriant Herba Artemisiae, in low-grades also.2. " detailed outline ": also, with the merit of improving eyesight, name, has again Semen Cassiae, Concha Haliotidis, all with merit person to this Horse hoof Semen Cassiae.Semen Cassiae is Semen Celosiae, and the so-called luxuriant Artemisia of Tao Shi is also.Semen Cassiae has two kinds, a kind of Horse hoof Semen Cassiae, and stem Senior Three, four chis, leaf is greater than Herba Medicaginis and this little last Ji, opens silk tree daytime, two biphase notes.Autumn is opened sulphureum Baker, and five go out.Tie angle as nascent thin Semen vignae sinensis, long five, six cun, the tens of grains of angle neutron, irregular being connected, shape is as Horse hoof, dark green, enters eyes medicine the best.A kind of Cassia sophera.All can make distillers yeast for two kinds, custom is exhaled as monopolizing cylinder.But the tender Seedling of Semen Cassiae Sopherae and flower and silver coin all can be boiled and eat and order cakes and sweetmeats, and all tough hardship in Horse hoof Semen Cassiae Seedling angle is not edible yet.
Fructus Lycii, nourishing the liver and kidney, replenishing vital essence to improve eyesight; For chronic consumptive disease damage of essence, soreness of waist and knee joint; Vertigo and tinnitus, interior-heat Xiao are thirsty, blood deficiency and yellow complexion, and blurred vision is not clear.Cure mainly caused by liver and kidney deficiency; Have a dizzy spell; Visual deterioration; Soreness of the waist and knees; Seminal emission is quenched one's thirst; Cough due to consumptive disease.The hepatic and renal YIN deficiency, blood deficiency, soreness of the waist and knees, chronic oculopathy, have a dizzy spell, suitable edible after the disease patient such as asthenia is thin and weak, diabetes, hypertension, hyperlipemia, arteriosclerosis, chronic hepatitis, fatty liver and cancer patient's radiotherapy, chemotherapy.The heat syndrome that all void are hyperfunction, the disease patient such as does not move back such as deficiency-heat after pulmonary tuberculosis later stage, diabetes yin asthenia generating intrinsic heat, infantile measles suitable edible.
Massa Medicata Fermentata, invigorating the spleen and regulating the stomach; Promoting digestion and removing stagnation.Main retention of food and drink; Dyspepsia; Distension and fullness in the abdomen; Inappetence; Vomiting dysentery.Control retention of food and drink, feeling of stuffiness in chest abdominal distention, vomiting dysentery, postnatal blood stasis stomachache, children's's enlarged abdomen is hard long-pending.Zhang Yuansu: nourishing the stomach gas.Control also white chaste tree.Materia Medica of Decoction: treat pathogenic wind in internal organs, the therapeutic method to keep the adverse QI flowing downwards in tune, the dyspepsia that disappears whets the appetite.Main cholera heart diaphragm gas, expectorant is contrary, and relieving restlessness , Po Disorder knot and tonify deficiency, remove cold air, except in the intestines and stomach, fills in, not lower food.Can control the hard large as dish of children's's abdomen, fullness in the chest, frequent fetal movement, or lumbago robs the heart, and hematochezia is more than." detailed outline ": removing stagnancy of indigested food and making QI downward, expectorant is let out dysentery distension against cholera.Sprain lumbago person, forged the wine decoction being taken warmly of quenching effective, and married woman wants galactopoiesis person puerperal, and stir-fry is ground wine and taken two money, day two." book on Chinese herbal medicine is stated ": the summer-heat that cures the wound, being affected by fluid-retention food, hinders overstrain, malaria flatulence due to stagnation of QI card, edema distension gathers, cough due to fluid-retention, vomiting regurgitation, cholera, blood-retention, pained, gastric abscess, hypochondriac pain, numbness flaccidity is dizzy, and heavy sensation of the body can not be eaten jaundice." book on Chinese herbal medicine is new again ": the scrofula that disappears cellulitis tumor.
Radix Salviae Miltiorrhizae, there is promoting blood circulation to remove blood stasis, detumescence hemostasis, anti-inflammatory analgetic, menstruction regulating and pain relieving, coronary artery dilator, improve myocardial ischemia situation, with all worries set aside, blood sugar lowering and the effect such as antibiotic reduce blood pressure, calm the nerves, to menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, the diseases such as angina pectoris have certain curative effect.In addition, modern medicine experiment showed, that Radix Salviae Miltiorrhizae also has the function of anti-platelet aggregation, reduction blood viscosity and the inside and outside blood coagulation system of adjusting, is that a kind of safety is treated again the natural Chinese medicine of cardiovascular disease reliably.For costa sternales hypochondriac pain, rheumatic arthralgia, lump in the abdomen caking, skin infection swells and ache, tumbling down is grieved, menoxenia, amenorrhea dysmenorrhea, puerperal stasis of blood pain etc.Treatment costa sternales pain, lump in the abdomen caking, and menoxenia, amenorrhea dysmenorrhoea have good effect, often apply with Rhizoma Chuanxiong compatibility.In treatment breast abdomen pain, belong to aspect qi depression to blood stasis, often coordinate the medicines such as Fructus Amomi, Lignum Santali Albi with using.For epidemic febrile disease heat, enter that macule is sent out in nutrient blood, body, coma is irritated.The medicines such as normal and Radix Rehmanniae, Cornu Bubali, Radix Scrophulariae are with use.For severe palpitation, insomnia.The medicines such as normal and Semen Ziziphi Spinosae, Semen Platycladi coordinate use together.
Fructus Alpiniae Oxyphyllae, temperature compensation astringency inducing, warm spleen antidiarrheal , Gu Dan takes the photograph saliva, and the kidney warming controlling nocturnal emission with astringent drugs reducing urination, cures mainly spleen-kidney vacuity cold, abdominal pain diarrhea; Or kidney qi deficiency and coldness frequent micturition, the enuresis, seminal emission, nebulousurine; Or the chronic diarrhea due to Deficiency and coldness of spleen and stomach and mouthful in saliva outflow and can not effector.1. Materia Medica of Decoction: " hands, meridian of Foot-TAI YIN, meridian of Foot-SHAO YIN." 2. " Thunder God is concocted property of medicine solution ": " enters spleen, stomach, kidney three warps." 3. " book on Chinese herbal medicine is through separating ": " enters liver channel of foot-Jueyin, lung meridian.
Fructus Mori, nourishing YIN and benefiting blood; Promote the production of body fluid; Intestine moistening.Having a dizzy spell of main deficiency of the liver and kindey and blood deficiency damage of essence; Soreness of waist tinnitus; Early whitening of beard and hair; Insomnia and dreamful sleep; Tianjin wound is thirsty; Quench one's thirst; Dryness of the intestine constipation.Fructus Mori both can food, can be used as medicine again, and the traditional Chinese medical science is thought the acid of Fructus Mori sweet in the mouth, cold nature, enters the heart, liver, kidney channel, is strengthening by means of tonics, the good fruit of the heart nourishing and intellengence improving, Fructus Mori has the YIN nourishing of enriching blood, promoting the production of body fluid to quench thirst, the effect such as intestine moistening is dry, Fructus Mori cures mainly deficiency of YIN-blood and having a dizzy spell of causing, tinnitus cardiopalmus, irritated insomnia, soreness of the waist and knees, early whitening of beard and hair, the diseases such as xerostomia, constipation with dry stool of quenching one's thirst.
Fructus Ligustri Lucidi, tonifying liver kidney yin, crow must improving eyesight, and modern medicine study thinks that the effect that Fructus Ligustri Lucidi can suppress helicobacter pylori can treat gastropathy, also has and suppresses purine abnormal metabolism for the treatment of gout and hyperuricemia.For the hepatic and renal YIN deficiency, soreness of waist tinnitus, early whitening of beard and hair; Unseeing, poor vision; Fever due to yin deficiency, gastropathy and gout and and hyperuricemia.1, Deficiency and coldness of spleen and stomach and insufficiency of kidney-YANG person prohibit clothes.2, Deficiency and coldness of spleen and stomach is had loose bowels and yang deficiency person avoids clothes.3, " Bencao Jingshu ": when assorted, protect taste medicine and green pepper is red warm and so on executing, probably not having stomachache to do the trouble of letting out.
Flos Chrysanthemi, Flos Chrysanthemi is Compositae herbaceos perennial, is one of traditional parts of generic medicinal plants of China, mainly with head inflorescence hyoscine.According to ancient books, record Flos Chrysanthemi sweet-bitter flavor, cold nature; There are the effects such as loose wind heat clearing away, liver heat removing and eyesight improving and detoxicating, relieving inflammation. puckery to xerostomia, hyperactivity of fire, order, or the limbs pain being caused by wind, cold, wet, numb disease all have certain curative effect.Cure mainly cold anemopyretic, headache etc.Dizzy, headache, tinnitus are had to preventive and therapeutic effect.Flos Chrysanthemi have Herba Dendranthematis indici and family chrysanthemum minute, family's chrysanthemum liver heat removing and eyesight improving wherein, the loose fire of Herba Dendranthematis indici toxic removing, sweetness and bitterness is slightly cold, heat-clearing and toxic substances removing all has certain effectiveness to eyes strain, headache, hypertension etc.Drug effect to chrysanthemum scented tea in Compendium of Material Medica is also documented in detail: property is sweet, be slightly cold, and has the effect of loose wind heat, suppressing the hyperactive liver improving eyesight.Shennong's Herbal thinks, Flos Chrysanthemi scented tea can " main all dizziness due to wind, swell and ache, order wish is de-, the dead flesh of skin, aversion to wind arthralgia chiefly caused by damp pathogen, takes for a long time promoting the circulation of QI, she making light of one's life by commiting suicide endures hardships prolongs life.”
Sargassum, softening the hard mass; Expectorant; Diuretic; Detumescent.Thyromegaly, a submental lymph nodes tuberculosis.Eliminating stagnation gas carbuncle, abdomen inner product piece, distending pain, the ring of abdomen hollow.Also can descend 12 kinds of edema, treat between skin and gather sudden and violent bursting, stay depressed heat, diuresis.Cure mainly: scrofula; Goiter; Gather; Edema; Foot gas; Painful and swollen testis; (Epileptic is ruined) hernia.1. " herbal classic ": main goiter gas, core under neck, broken eliminating stagnation gas, the hard gas of carbuncle lump in the abdomen, ring up and down in abdomen, lower 12 edema.2. " not Lu ": treat between skin and gather, sudden and violent Huang, stays gas, accumulation of heat, diuresis.3. " property of medicine opinion ": control dry phlegm-syndrome knot full, treat hernia tenesmus, pain core is swollen, removes active borhorygmus, faint uttering a word.4. the Meng numerous: led the cloudy gas of man, often eaten it, man Huang disease disappears.5. " Haiyao Bencao, Oversea Materia Medica ": main dyspepsia does not disappear, five expectorant of separating are stopped up, aqueous vapor edema, beriberi, sensation of gas rushing.6. " book on Chinese herbal medicine covers bamboo fish trap ": control scrofula between item, wart capsule under the neck that disappears, dredging water passages, the logical difficulty in urination becomes to drench, and removing water retention by purgation gas, except distension swells.7. " modern Practical Chinese medicinal ": control the diseases such as chronic tracheitis.
Endothelium Corneum Gigeriae Galli, promoting digestion and invigorating the stomach is aid digestion, arresting seminal emission.Can promote gastric secretion, improve gastric acidity and eupepsy, stomach motor function obviously be strengthened, rapid gastric emptying.Removing food stagnancy is stagnant, strengthening the spleen and stomach.Control food stagnation distension, vomiting regurgitation, dysentery, infantile malnutrition, quenches one's thirst, incontinence of urine, sore throat tonsillitis, ulcerative gingivitis aphtha.1. " herbal classic ": the main profit of letting out.2. " not Lu ": main normal urination, incontinence of urine, heat extraction is only tired.3. " Japan hanako materia medica ": stopping leak essence, and hematuria, metrorrhagia, leukorrhagia, hemorrhoidal hamorrhage, dysentery.4. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": alleviating distention in middle-JIAO spleen invigorating, mill stomach helps digestion.Control children's's breast food knot stagnant, the large muscle of tripe is blue or green, mass in the abdomen infantile malnutrition.5. " detailed outline ": control children's's intermittent fever due to retention of food, treatment adult is dripping, regurgitation, and the wine that disappears is long-pending, main inflammation of the throat, tonsillitis, all aphthas, all skin ulcers of ulcerative gingivitis.6. " book on Chinese herbal medicine is stated ": control diseases due to endogenous heat of ZANG FU organs.7. " herbal classic is met former ": control eyes and hide from view.8. " book on Chinese herbal medicine is new again ": reduce phlegm, regulate the flow of vital energy, dampness removing.9. " Records of Tradition Chinese and Western Medicine in Combination ": control Xuan ringworm abdominal mass, stimulate the menstrual flow and close.
Magnetitum, suppressing the hyperactive liver and subsiding YANG; Calm the nerves relieving convulsion; Hearing-improing and eyesight improving; Helping inspiration to relieve asthma.Cure mainly: main dizzy; Order flower; Deaf; Tinnitus; Palpitation with fear; Insomnia, the dyspnea of suffering from a deficiency of the kidney.1. Collective Notes to the Canon of Materia medica: Radix Bupleuri makes for it.Dislike Paeonia suffruticosa, Folium illicii Lanceolati.Fear Huangshi fat.Kill ferrum poison.2. " Bencao Congxin ": feel frustrated in important city, can temporary and can not be of a specified duration.More taste void person, should not take, take for a long time.
Semen Celosiae, liver heat removing, improving eyesight, nebula removing.For liver-heat conjunctival congestion, the nebula of looking unfamiliar film, blurring of vision, dizziness due to liver-fire.1, liver heat removing and eyesight improving: be mainly used in flaming up of liver-fire, conjunctival congestion and swelling pain, the raw nebula film of order, poor vision.2, these product also can be used for liver-fire type hypertension.
Rhizoma Seu Herba Bergeniae, another name stone Chinese cabbage.Medical material Ji Yuan: be the herb of goatweed triaenophora rupestris.Latin plant animal mineral name: Triaenophora rupestris(Hemsl.) solereder[Rehmannia rupestris Hemsl.].Gather and store: summer, autumn gather, and dry.Ecological environment: be born on the cliff of height above sea level 290-1200m.Be distributed in Hubei, Sichuan.Sweet in the mouth; Cool in nature.Cure mainly the kidney invigorating; Improving eyesight; Regulating menstruation.The confused many tear of argument; Lumbago due to renal deficiency; Menoxenia.
Shellfish tooth, cures mainly clearing away heart-fire for tranquillization, suppressing the hyperactive liver improving eyesight.Be used for the dysphoria and insomnia of palpitating with fear, children's's macule, conjunctival congestion nebula.Medical material is practised minute Concha Erosariae seu Cypraeae and cowry shell two classes, is used as medicine and take Concha Erosariae seu Cypraeae as many.Concha Erosariae seu Cypraeae is Cypraeidae animal erosaria caputserpentis Erosaria (Ravitrona) caputserpentis (L.), Cypraealynx Cypraca (Lyncina) lynx (L.), silk ribbon attached to an official seal or a medal shellfish Mauritia arabica (L.) or eyeball shellfish (intending name) Erosaria (Ravitrona) helvola (L.).Cowry shell is Cypraeidae animal ring grain Cypraeamoneta Monetaria (Ornametaria) annulus (L.), plan Fructus Jujubae shellfish Erronea errones (L.) or Cypraeamoneta Monetaria moneta (L.).With shell, be used as medicine.Between 5~July, from marine, fish for, except fleshing, clean and dry.Nature and flavor are salty, flat.
Flos Eriocauli, wind and heat eliminating, improving acuity of vision and removing nebula.Cure mainly and control corneal nebula, night blindness, headache, toothache, sore throat, epistaxis.1, wind heat conjunctival congestion and swelling pain, photophobia, the nebula of looking unfamiliar film.The frivolous liter of this product is loose, kind women's head-ornaments wind heat, the improving acuity of vision and removing nebula evacuated, with control in wind heat, attack due to conjunctival congestion and swelling pain, the many tear of photophobia, the nebula of looking unfamiliar film person, can with the compatibility such as Herba Schizonepetae, Semen Cassiae, Radix Gentianae, as Flos Eriocauli soup (" Precious Book of Ophthalmology ").2, headache due to pathogenic wind-heat: get its dispelling wind and heat pathogens and control headache due to pathogenic wind-heat, often joining Herba Menthae, Flos Chrysanthemi, Fructus Arctii etc. medicinal.Flos Eriocauli is for conjunctival congestion cataracta, the many tear of photophobia, nyctalopia.Flos Eriocauli light weight is pungent loose, is longer than and evacuates wind-heat of liver channel and improving acuity of vision and removing nebula, is the conventional product of ophthalmology.Conjunctival congestion cataracta due to all wind heat, photophobia is shed tears, and often joins Herba Equiseti Hiemalis, Flos Buddlejae, Fructus Atriplicis Sibiricae with dispelling wind and heat pathogens; If wind heat more very, liver-fire is partially prosperous, and conjunctival congestion and swelling pain is more acute, joins Radix Gentianae, Flos Chrysanthemi, Semen Cassiae etc., and with dispelling wind and removing heat, liver heat removing and eyesight improving, as " Precious Book of Ophthalmology " Flos Eriocauli soup; If corneal nebula after pox, joins Periostracum Cicadae, testa mungo with dispelling pathogenic wind for improving eyesight, heat-clearing and toxic substances removing is as loose in " Standards of Diagnosis and Treatment " Flos Eriocauli.As for treatment nyctalopia, Gu Qingcao can with Hepar Sus domestica, or join again Rhizoma Atractylodis, the same use of Faeces Vespertilionis, with liver-benefiting eye-brightening." proper book on Chinese herbal medicine ": " obtain wether liver, control night blindness in children." " must join book on Chinese herbal medicine ": " join Pheretima, the smoked nose of Olibanum, control headache; Join corneal nebula after Pulvis concha Mactrae, Hepar Sus domestica treatment of smallpox.
Faeces Vespertilionis, optic atrohic blindness; Nyctalopia; Conjunctival congestion and swelling pain; Subconjuctival hemorrhage; Inside and outside cataracta; Infantile malnutrition; Scrofula; Malaria.1. " detailed outline ": Faeces Vespertilionis and Vespertilio are all fainted cloudy Liver Channel blood system medicine also, energy promoting blood circulation to remove stagnancy, therefore the corneal nebula blindage of controlling, malaria infantile malnutrition is frightened, drenches band, scrofula, carbuncle, the disease of the moon of all fainting is also.2. " Bencao Jingshu ": Faeces Vespertilionis, the main improving eyesight of moderns, controls blindness and hide from view.Its acrid in the mouth is cold, is into meridian of Foot-JUE YIN medicine, " herbal classic " all cards of lead, total belong to be through send out, get the loose inside and outside knot of its pungent energy stagnant, therefore tremble with fear the heap soil or fertilizer over and around the roots of energy dehematize steam also.Though right main treatment is many, property has exclusive, and outside improving eyesight, Yu Jieke slightly.3. " herbal classic ": interarea carbuncle, pain when skin is washed, QI and blood in abdomen, broken cold and heat gather, except palpitation with fear.4. " not Lu ": remove dark complexion.5. Tang Materia Medica: wine takes tool for weighing medicine in ancient China, main dead fetus in the uterus.6. " Japan hanako materia medica ": scrofula is controlled in speculation in stocks.7. amplification on Canon of Materia Medica: close infantile malnutrition medicine.8. " detailed outline ": control blindness, hide from view, improving eyesight, except malaria.
 
Embodiment 1 cold compress agent
The preparation process of cold compress agent of the present invention is: first by Semen Persicae 1500g, Flos Carthami 1200g, Radix Angelicae Sinensis 1000g, Rhizoma Chuanxiong 1800g, Radix Rehmanniae Preparata 1200g, Radix Paeoniae Alba 1500g, Fructus Atriplicis Sibiricae 1200g, Semen Cassiae 1400g, Fructus Lycii 1800g, Massa Medicata Fermentata 1200g, Radix Salviae Miltiorrhizae 1000g, Fructus Alpiniae Oxyphyllae 1200g, Fructus Mori 1400g, Fructus Ligustri Lucidi 1200g, Flos Chrysanthemi 1500g, Rhizoma Dioscoreae 1000g, Sargassum 1200g, Fructus Schisandrae Chinensis 1500g, Endothelium Corneum Gigeriae Galli 1200g, Pericarpium Citri Reticulatae 1500g, Magnetitum 1000g, Semen Celosiae 1200g, Rhizoma Seu Herba Bergeniae 1500g, shellfish tooth 2000g, Flos Eriocauli 1600g and Faeces Vespertilionis 1200g, be ground into coarse powder, further pulverize again, cross 120 mesh sieves, collection obtains fine powder a by the fine powder of 120 mesh sieves, can not by the coarse powder of 120 mesh sieves, drop into multi-function extractor again and extract twice, and add for the first time 8 times of water gagings and decoct 2 hours, and add for the second time 6 times of water gagings and decoct 2 hours, merge decocting liquid twice, filter to get filtrate, filtrate heating is concentrated into pasty state, puts into after 80 ℃ of oven dry of baking oven coolingly, grind to form fine powder b, fine powder a is mixed standby afterwards with fine powder b, then by Borneolum Syntheticum 1500g extraction by steam distillation, obtain crystal c, crystal c is added in the mixture of fine powder a and fine powder b, mix and add appropriate glycerol, glycerol addition to account for 6 times of fine powder mixture quality, furnishing paste, packs into after sterilization in colored bottle, puts into 0 ℃ of-4 ℃ of storage of refrigerator-freezer standby.
Embodiment 2 eye drop
The preparation process of eye drop of the present invention is:
A, get Semen Persicae 1500g, Flos Carthami 1200g, Radix Angelicae Sinensis 1700g, Rhizoma Chuanxiong 1000g, Radix Rehmanniae Preparata 1300g, Radix Paeoniae Alba 1000g, Fructus Atriplicis Sibiricae 1200g, Semen Cassiae 1500g, Fructus Lycii 1000g, Massa Medicata Fermentata 1200g, Radix Salviae Miltiorrhizae 1800g, Fructus Alpiniae Oxyphyllae 1400g, Fructus Mori 1200g, Fructus Ligustri Lucidi 1000g, Flos Chrysanthemi 1300g, Rhizoma Dioscoreae 1400g, Sargassum 1800g, Fructus Schisandrae Chinensis 1200g, Endothelium Corneum Gigeriae Galli 1000g, Pericarpium Citri Reticulatae 1200g, Magnetitum 1500g, Semen Celosiae 1200g, Rhizoma Seu Herba Bergeniae 1600g, shellfish tooth 1200g, Flos Eriocauli 1000g and Faeces Vespertilionis 1500g, add water extraction 2 times, adding for the first time 6 times of water gagings decocts 2 hours, adding for the second time 5 times of water gagings decocts 1 hour, 2 extracting solution are merged, filter, the extractum 1 that when concentrating under reduced pressure obtains 80 ℃, relative density is 1.04~1.10, medicinal residues are standby,
B, medicinal residues are added to 80% soak with ethanol 1.5 hours, extract twice, each 2 hours, merge extractive liquid,, filters, concentrated, 80-160 order filters, the 6000-10000 rev/min of supernatant after centrifugal, is the ultrafiltration post ultrafiltration of 5000-10000 through the molecular weight that dams, 1.25 extractum 2 when ultrafiltrate concentrating under reduced pressure relative density is 60 ℃;
C, extractum 1 and extractum 2 is mixed, add 0.06% sodium chloride and the 60-80 distilled water doubly that mix extractum gross mass, and to add concentration be that to regulate PH be 6.0-7.0 to 4% sodium hydroxide solution, add again 0.2% active carbon to boil 10 minutes, filter packing, sterilizing, obtains eye drop.
Embodiment 3 tablets
The preparation process of tablet of the present invention is: get Semen Persicae 1200g, Flos Carthami 1800g, Radix Angelicae Sinensis 2000g, Rhizoma Chuanxiong 1500g, Radix Rehmanniae Preparata 1200g, Radix Paeoniae Alba 1800g, Fructus Atriplicis Sibiricae 1000g, Semen Cassiae 1300g, Fructus Lycii 1200g, Massa Medicata Fermentata 1600g, Radix Salviae Miltiorrhizae 1400g, Fructus Alpiniae Oxyphyllae 1000g, Fructus Mori 1500g, Fructus Ligustri Lucidi 1800g, Flos Chrysanthemi 1800g, Rhizoma Dioscoreae 1000g, Sargassum 1500g, Fructus Schisandrae Chinensis 1800g, Endothelium Corneum Gigeriae Galli 1000g, Pericarpium Citri Reticulatae 2100g, Magnetitum 2800g, Semen Celosiae 1000g, Rhizoma Seu Herba Bergeniae 1800g, shellfish tooth 1400g, Flos Eriocauli 1500g and Faeces Vespertilionis 1700g, put into 10 times of amount ethanol, heating and refluxing extraction 2 times, each 45 minutes, extract active ingredient, 2 extracting solution are merged standing, obtain extracting solution a, medicinal residues are standby, medicinal residues are added to 10 times of water gagings, and heating and refluxing extraction 3 times, each 1 hour, merges to obtain extracting solution b by 3 extracting solution, merge extractive liquid, a and extracting solution b, decompression recycling ethanol to be concentrated into liquor strength be 0.5g crude drug/mL, after sucking filtration, the filtrate that while obtaining 20 ℃, relative density is 1.06, the macroporous adsorptive resins eluting twice that above-mentioned filtrate is 10L through volume, first uses deionized water or the distilled water eluting of 10 times of resin column volumes, then uses 95% ethanol elution of 5 times of resin column volumes, collects ethanol elution, removes solvent, obtains raw material medicinal liquid, add starch to be pressed into tablet.
Embodiment 4 pills
The preparation process of the present invention's honey refining pill is: get Semen Persicae 1600g, Flos Carthami 2000g, Radix Angelicae Sinensis 1800g, Rhizoma Chuanxiong 1300g, Radix Rehmanniae Preparata 1000g, Borneolum Syntheticum 1500g, Radix Paeoniae Alba 1200g, Fructus Atriplicis Sibiricae 1500g, Semen Cassiae 1100g, Fructus Lycii 2000g, Massa Medicata Fermentata 1500g, Radix Salviae Miltiorrhizae 1200g, Fructus Alpiniae Oxyphyllae 1100g, Fructus Mori 1600g, Fructus Ligustri Lucidi 1000g, Flos Chrysanthemi 1400g, Rhizoma Dioscoreae 1300g, Sargassum 1000g, Fructus Schisandrae Chinensis 2100g, Endothelium Corneum Gigeriae Galli 1600g, Pericarpium Citri Reticulatae 1500g, Magnetitum 1800g, Semen Celosiae 1300g, Rhizoma Seu Herba Bergeniae 1800g, shellfish tooth 1500g, Flos Eriocauli 1200g and Faeces Vespertilionis 1000g, soak 1 hour, heated and boiled 30 minutes, filter, filtrate for later use, filtering residue adds water, and heating, boils 30 minutes for the second time, refilters filtrate for later use, filtering residue adds water again, and heated and boiled is 30 minutes for the third time, filters, three filtrates are combined, and heating is concentrated into pasty state, puts into baking oven, is controlled at 75 ℃, is cooled to be Powderedly twisted into ball together with being mixed in right amount with Mel after oven dry, every 5g of take packs as a ball wax seal.
 
Pharmacology pharmacodynamic report
1, acute toxicity test report
Test method: the eye drop of the embodiment of the present invention 2 of take is object, selects 20 white mice to test, and is divided into matched group and test group, each 10,3 times of 10 white mice intravenous injections to test group of getting clinical consumption per day, observe 7.Equal strong the depositing of 20 white mouse as a result, its activity, diet, hair, Excreta are no abnormal, have no toxic reaction.Toxicity test proves, the not toxic effect of this medicine and untoward reaction, and clinical practice is safe and reliable.
2, long term toxicity test report
Test method one: the tablet of the embodiment of the present invention 3 of take is object, select 20 identical Canis familiaris L.s of ripe vital sign to test, be divided into three groups of one group of matched group and test group, 20 Canis familiaris L.s are carried out to same food nursing, and 15 1 times, 3 times and 5 times of mixing respectively clinical medicine consumption in food of test group group are fed.Nursing is carried out two months, and 20 Canis familiaris L.s are observed, and animal all survives, and has no toxic reaction.Blood and bone marrow smear, internal organs pathological section is there are no the pathological change of toxicity meaning.
Test method two: using the pill of the embodiment of the present invention 4 as object, select 20 rats to test.Be divided at random two groups, respectively it filled with to food 5 times and 10 times of pharmaceutical quantities.Carry out 1 month continuously, observe, 20 rats, before vital sign and dispensing,, there is not any untoward reaction in indifference, behavior is normal, has no toxic reaction.
3, hypersensitive test report
Test method: using the cold compress agent of the embodiment of the present invention 1 as object, select 30 identical Cavia porcelluss of vital sign to test.Be divided at random 5 groups, one group of matched group and four groups of test group, carry out subcutaneous medication to 24 of test group Cavia porcelluss respectively, and dosage is that 2LD50,4 LD50,6 LD50,8 LD5(LD50 are about 1.5g/kg respectively), medication is carried out 4 weeks.The Cavia porcellus of observing four groups of test group and one group of matched group, all there is not any discomfort in skin, and behavior is normal, blood internal organs have no pathological changes.
By pharmacology pharmacodynamic, test, can learn, Chinese medicine composition of the present invention, does not have system custom, holds toxicity and sensitization.
 
Clinical data
1. data and method
Select the Aged-related Cataract Patients that ,Wo institute receives during in July, 2010-2012 year July to amount to 300 examples.Wherein, in 300 routine patients, the case patient of age the right side of fifty has 50 examples, case patient's 100 examples in age 50-60 year, and the case patient of age above 60 years has 150 examples.In patient, in various degree suffer from senile cataract, symptom for oculogyral shade at the moment, gradual Silent Neuritis visual deterioration, monocular diplopia or look more, iridization, photophobia and dazzle.Eyes are ill, have successively, and the order of severity differs.This 300 routine patient is divided into matched group 120 example and treatment group 180 examples at random, treats contrast.
2. criterion of therapeutical effect
Recovery from illness: senile cataract symptom recovery from illness; Effective: symptom is obviously alleviated; Invalid: symptom is invalid.
3. Therapeutic Method
3.1 are divided into four groups at random by 180 routine patients for the treatment of group, and according to the embodiment of the present invention, 1-4 treats.
Treat one group: the 45 routine patients of this treatment group use the cold compress agent of embodiment 1 to treat.Treating every bu morning, noon and afternoon three times, after eye is cleaned, the cold compress agent of 5g is spread on to eye at every turn and carry out washing away for 20 minutes, 7 days is a course for the treatment of, and treatment is carried out 1-3 the course for the treatment of.After medication, have 42 routine patient's symptom recoveries from illness, 1 routine patient's symptom is effectively alleviated, and 2 routine patients are invalid.In medication process, patient has no side effect.With nearly half a year, not recurrence.
Treat two groups: the 45 routine patients of this treatment group use the eye drop of embodiment 2 to treat.Treat every bu morning, noon and afternoon three times, the eye drop that is 2% by concentration is aimed at canthus and is dripped medicine, and drip medicine 2-3 at every turn and drip, within 7 days, be a course for the treatment of, treat and carry out 1-3 the course for the treatment of.After medication, have 43 routine patient's symptom recoveries from illness, 1 routine patient's symptom is effectively alleviated, and 1 routine patient is invalid.In medication process, patient has no side effect.With nearly half a year, not recurrence.
Treat three groups: the 45 routine patients of this treatment group use the tablet of embodiment 3 to treat.Treat every bu morning, noon and afternoon three times, each two, the dosage of every 0.4g, 7 days is a course for the treatment of, and treatment is carried out 1-3 the course for the treatment of.After medication, have 41 routine patient's symptom recoveries from illness, 3 routine patient's symptoms are effectively alleviated, and 1 routine patient is invalid.In medication process, patient has no side effect.With nearly half a year, not recurrence.
Treat four groups: the 45 routine patients of this treatment group use the pill of embodiment 4 to treat.Treat every bu morning, noon and afternoon three times, each ball, every ball is 5g, within 7 days, is a course for the treatment of, treatment is carried out 1-3 the course for the treatment of.After medication, have 44 routine patient's symptom recoveries from illness, 1 routine patient's symptom is effectively alleviated, and 0 routine patient is invalid.In medication process, patient has no side effect.With nearly half a year, not recurrence.
3.2 by 120 routine patient's random packet of matched group, are divided into three groups, use different medicines to treat.
Contrast one group: 40 people of this matched group use Benzydalysine eye drop to treat.Eye drip.3 times on the one, each 1~2, treat 4 weeks.After medication, have 30 routine patient's symptom recoveries from illness, 5 routine patient's symptoms are effectively alleviated, and 5 routine patients are invalid.In medication process, there are the untoward reaction such as 5 routine patients occur dysphagia, nausea,vomiting,diarrhea, shed tears, contact dermatitis.With nearly half a year, there are 8 routine Patients on Recurrences.
Contrast two groups: 40 people of this matched group use the clever injection of eye to treat.Intramuscular injection; Every day 1 time, each 2ml.Treat 30.After medication, have 30 routine patient's symptom recoveries from illness, 4 routine patient's symptoms are effectively alleviated, and 6 routine patients are invalid.In medication process, there are 5 routine patients to go out to lose face and do untoward reaction such as grade.With nearly half a year, there are 5 routine Patients on Recurrences.
Contrast three groups: 40 people of this matched group use An Tai Dian Eye Dropes to treat.Eye drip: every day 2~4 times, treat 4 weeks.After medication, have 31 routine patient's symptom recoveries from illness, 3 routine patient's symptoms are effectively alleviated, and 6 routine patients are invalid.In medication process, have the untoward reaction such as local excitation sense, conjunctival sac secretions increase after having 7 routine patient's eye drips.With nearly half a year, there are 10 routine Patients on Recurrences.
By contrast, can learn, medicine of the present invention have curative effect fast, effective, have no side effect, the feature such as curative effect is lasting.
Concrete case
Case 1 Wang, female, 65 years old, suffer from senile cataract existing 2 years, Symptoms is the symptoms such as photophobia and dazzle, uses the cold compress agent of the embodiment of the present invention 1 to treat.Treating every bu morning, noon and afternoon three times, after eye is cleaned, the cold compress agent of 5g is spread on to eye at every turn and carry out washing away for 20 minutes, 7 days is a course for the treatment of, and treatment is carried out 3 courses for the treatment of.After medication, symptom recovery from illness, has no side effect.With nearly half a year, not recurrence.
Case 2 Lee, man, 63 years old, suffer from senile cataract one year, Symptoms is the symptoms such as visual deterioration, monocular diplopia, uses the eye drop of the embodiment of the present invention 2 to treat.Treat every bu morning, noon and afternoon three times, the eye drop that is 2% by concentration is aimed at canthus and is dripped medicine, and drip medicine 2-3 at every turn and drip, within 7 days, be a course for the treatment of, treat and carry out 3 courses for the treatment of.After medication, symptom recovery from illness, has no side effect.With nearly half a year, not recurrence.
Case 3 grandsons, female, 70 years old, to suffer from senile cataract and have half a year, Symptoms, for there being the symptoms such as shade at the moment, is used the tablet of the embodiment of the present invention 3 to treat.Treat every bu morning, noon and afternoon three times, each two, the dosage of every 0.4g, 7 days is a course for the treatment of, and treatment is carried out 3 courses for the treatment of.After medication, symptom recovery from illness, has no side effect.With nearly half a year, not recurrence.
Case 4 tunnels, man, 68 years old, suffer from the symptoms such as senile cataract has 2 years, and Symptoms is visual deterioration, use the pill of the embodiment of the present invention 4 to treat.Treat every bu morning, noon and afternoon three times, each ball, every ball is 5g, within 7 days, is a course for the treatment of, treatment is carried out 3 courses for the treatment of.After medication, symptom recovery from illness, has no side effect.With nearly half a year, not recurrence.
 
The foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.

Claims (6)

1. a Chinese medicine composition for the treatment of senile cataract, it is characterized in that, in described Chinese medicine composition, the ratio of weight and number of various crude drug is: 10~25 parts, Semen Persicae, 10~25 parts, Flos Carthami, 10~25 parts of Radix Angelicae Sinensis, 10~25 parts of Rhizoma Chuanxiongs, 10~25 parts, Radix Rehmanniae Preparata, 10~20 parts of Borneolum Syntheticums, 10~25 parts of the Radix Paeoniae Albas, 10~20 parts of Fructus Atriplicis Sibiricaees, 10~20 parts of Semen Cassiae, 10~25 parts of Fructus Lyciis, 10~25 parts of Massa Medicata Fermentata, 10~25 parts of Radix Salviae Miltiorrhizaes, 10~25 parts of Fructus Alpiniae Oxyphyllae, 10~25 parts of Fructus Mori, 10~25 parts of Fructus Ligustri Lucidi, 10~20 parts of Flos Chrysanthemis, 10~20 parts of Rhizoma Dioscoreaes, 10~20 parts of Sargassums, 10~25 parts of Fructus Schisandrae Chinensis, 10~20 parts of Endothelium Corneum Gigeriae Galli, 10~25 parts of Pericarpium Citri Reticulataes, 10~30 parts of Magnetitums, 10~20 parts of Semen Celosiae, 10~20 parts of Rhizoma Seu Herba Bergeniaes, 10~20 parts, shellfish tooth, 10~20 parts of 10~20 parts of Flos Eriocaulis and Faeces Vespertilioniss.
2. the Chinese medicine composition for the treatment of senile cataract according to claim 1, it is characterized in that, in described Chinese medicine composition, the ratio of weight and number of various crude drug is: 10~25 parts, Semen Persicae, 15~25 parts, Flos Carthami, 10~25 parts of Radix Angelicae Sinensis, 20~25 parts of Rhizoma Chuanxiongs, 15~25 parts, Radix Rehmanniae Preparata, 10~20 parts of Borneolum Syntheticums, 10~25 parts of the Radix Paeoniae Albas, 10~20 parts of Fructus Atriplicis Sibiricaees, 10~20 parts of Semen Cassiae, 20~25 parts of Fructus Lyciis, 20~25 parts of Massa Medicata Fermentata, 10~25 parts of Radix Salviae Miltiorrhizaes, 10~15 parts of Fructus Alpiniae Oxyphyllae, 10~20 parts of Fructus Mori, 10~20 parts of Fructus Ligustri Lucidi, 10~20 parts of Flos Chrysanthemis, 10~15 parts of Rhizoma Dioscoreaes, 10~15 parts of Sargassums, 10~20 parts of Fructus Schisandrae Chinensis, 10~15 parts of Endothelium Corneum Gigeriae Galli, 10~15 parts of Pericarpium Citri Reticulataes, 10~20 parts of Magnetitums, 15~20 parts of Semen Celosiae, 10~20 parts of Rhizoma Seu Herba Bergeniaes, 10~20 parts, shellfish tooth, 10~20 parts of 10~15 parts of Flos Eriocaulis and Faeces Vespertilioniss.
3. the Chinese medicine composition for the treatment of senile cataract according to claim 1 and 2, it is characterized in that, in described Chinese medicine composition, the ratio of weight and number of various crude drug is: 10~20 parts, Semen Persicae, 10~15 parts, Flos Carthami, 10~20 parts of Radix Angelicae Sinensis, 10~20 parts of Rhizoma Chuanxiongs, 10~20 parts, Radix Rehmanniae Preparata, 10~15 parts of Borneolum Syntheticums, 10~15 parts of the Radix Paeoniae Albas, 10~15 parts of Fructus Atriplicis Sibiricaees, 10~15 parts of Semen Cassiae, 10~20 parts of Fructus Lyciis, 10~20 parts of Massa Medicata Fermentata, 10~20 parts of Radix Salviae Miltiorrhizaes, 10~25 parts of Fructus Alpiniae Oxyphyllae, 20~25 parts of Fructus Mori, 10~25 parts of Fructus Ligustri Lucidi, 10~15 parts of Flos Chrysanthemis, 10~20 parts of Rhizoma Dioscoreaes, 10~20 parts of Sargassums, 20~25 parts of Fructus Schisandrae Chinensis, 15~20 parts of Endothelium Corneum Gigeriae Galli, 15~25 parts of Pericarpium Citri Reticulataes, 20~30 parts of Magnetitums, 10~20 parts of Semen Celosiae, 10~15 parts of Rhizoma Seu Herba Bergeniaes, 10~15 parts, shellfish tooth, 10~15 parts of 10~20 parts of Flos Eriocaulis and Faeces Vespertilioniss.
4. the preparation method of the Chinese medicine composition of the treatment senile cataract as described in claim 1-3 any one, it is characterized in that, the dosage form of described Chinese medicine composition is cold compress agent, described preparation process is: first the described crude drug except Borneolum Syntheticum is ground into coarse powder, further pulverize again, cross 120 mesh sieves, the fine powder of collecting by 120 mesh sieves obtains fine powder a; Can not by the coarse powder of 120 mesh sieves, drop into multi-function extractor again and extract twice, and add for the first time 4-6 times of water gaging and decoct 1-2 hour, and add for the second time 3-5 times of water gaging and decoct 1-2 hour, merge decocting liquid twice, filter to get filtrate; Filtrate heating is concentrated into pasty state, puts into after 80 ℃ of oven dry of baking oven coolingly, grind to form fine powder b, fine powder a is mixed standby afterwards with fine powder b; Then by Borneolum Syntheticum extraction by steam distillation, obtain crystal c; Crystal c is added in the mixture of fine powder a and fine powder b, mix add appropriate glycerol, glycerol addition be fine powder mixture gross mass 2-8 doubly, furnishing paste, packs into after sterilization in colored bottle, puts into 0 ℃ of-4 ℃ of storage of refrigerator-freezer standby.
5. a preparation method for the Chinese medicine composition of the treatment senile cataract as described in claim 1-3 any one, is characterized in that, the dosage form of described Chinese medicine composition is eye drop, and described preparation process is:
A, get described crude drug and add water extraction 2 times, add for the first time 4-6 times of water gaging and decoct 1-2 hour, add for the second time 3-5 times of water gaging and decoct 1-2 hour, 2 extracting solution are merged, filter, the extractum 1 that when concentrating under reduced pressure obtains 80 ℃, relative density is 1.04~1.10, medicinal residues are standby;
B, medicinal residues are added to 60-90% soak with ethanol 0.5-1.5 hour, extract twice, each 1-2 hour, merge extractive liquid,, filters, concentrated, 80-160 order filters, and 6000-10000 rev/min centrifugal, gets supernatant, through the molecular weight that dams, be the ultrafiltration post ultrafiltration of 5000-10000,1.25 extractum 2 when ultrafiltrate concentrating under reduced pressure relative density is 60 ℃;
C, extractum 1 and extractum 2 is mixed, add 0.06% sodium chloride and the 60-80 distilled water doubly that mix extractum gross mass, and to add concentration be that to regulate PH be 6.0-7.0 to 4% sodium hydroxide solution, add again 0.2% active carbon to boil 10 minutes, filter packing, sterilizing, obtains eye drop.
6. the Chinese medicine composition of the treatment senile cataract as described in any one in claim 1-3, it is characterized in that, the dosage form of described Chinese medicine composition is: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, eye drop, suck agent, granule, electuary, honey pill agent, powder, sublimed preparation, solution, injection, cold compress agent, suppository, plaster, syrup, powder or spray.
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CN104288645A (en) * 2014-10-27 2015-01-21 邓维新 Traditional Chinese medicine for treating senile cataract
CN104623318A (en) * 2015-03-12 2015-05-20 周晓明 Traditional Chinese medicine preparation for pterygium and preparation method of traditional Chinese medicine preparation
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CN108175819A (en) * 2018-03-07 2018-06-19 黑龙江中医药大学 It is a kind of to be used to treat Chinese medicine composition of cataract and its preparation method and application

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CN103860942A (en) * 2014-03-31 2014-06-18 刘洁 Drug for treating phlegm turbidity nasopharynx cancer and preparation method thereof
CN104288645A (en) * 2014-10-27 2015-01-21 邓维新 Traditional Chinese medicine for treating senile cataract
CN104707006A (en) * 2015-03-03 2015-06-17 李军 Radioactive preparation capable of promoting blood circulation and dredging meridians for cataract patients and preparation thereof
CN104623318A (en) * 2015-03-12 2015-05-20 周晓明 Traditional Chinese medicine preparation for pterygium and preparation method of traditional Chinese medicine preparation
CN105641038A (en) * 2016-03-26 2016-06-08 齐齐哈尔市前进医药有限责任公司 Yanmaitong eyedrops and preparation method thereof
CN107496806A (en) * 2017-09-07 2017-12-22 成都兴倍加生物科技有限责任公司 A kind of pill medicine for treating cataract of old people and preparation method thereof
CN108175819A (en) * 2018-03-07 2018-06-19 黑龙江中医药大学 It is a kind of to be used to treat Chinese medicine composition of cataract and its preparation method and application

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