CN104689193A - Heat clearing antidote for treating pneumonia and preparation method - Google Patents

Heat clearing antidote for treating pneumonia and preparation method Download PDF

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CN104689193A
CN104689193A CN201510134462.7A CN201510134462A CN104689193A CN 104689193 A CN104689193 A CN 104689193A CN 201510134462 A CN201510134462 A CN 201510134462A CN 104689193 A CN104689193 A CN 104689193A
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herba
parts
radix
pneumonia
dry
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霍传奇
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Abstract

The invention discloses a heat clearing antidote for treating pneumonia. The heat clearing antidote is mainly prepared by, by mass, the raw material medicine of 12-15 parts of canscora lucidissima, three to six parts of roxburgh peristrophe herbs, 19-25 parts of platycodon grandiflorum, 12-16 parts of buttonbush, nine to 15 parts of small botrypus virginianus, 16-20 parts of trichosanthes kirilowii maxim, 15-21 parts of dragonhead, 16-25 parts of radix bupleuri, six to ten parts of stemona, nine to 16 parts of aster, 10-16 parts of hemipilia flabellate, eight to 13 parts of mother chrysanthemum, nine to 14 parts of cirrhopetalnm andersonii hook, 11-18 parts of honeysuckle, eight to 16 parts of scutellaria indica, nine to 15 parts of gardenia jasminoides ellis and seven to 14 parts of fishing stems. The formula of the heat clearing antidote has the functions of clearing heat and fire, moistening the lung and relieving asthma, relieving cough and reducing sputum and the like, traditional Chinese medicine herb materials are adopted as raw materials, precise compatibility of medicines is achieved, reasonable preparation is carried out, all prepared dosage forms are safe and reliable, and through clinical verifications, the prepared products are obvious in treatment effect, and the pneumonia is not likely to reappear after being cured.

Description

The formula for clearing heat and removing toxicity for the treatment of pneumonia and preparation method
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of formula for clearing heat and removing toxicity and preparation method for the treatment of pneumonia.
Background technology
Pneumonia refers to last air flue eventually, the inflammation of alveolar and interstitial lung.Cause the cause of disease of pneumonia very complicated, comprise antibacterial, virus, mycoplasma etc. multiple, wherein bacterial pneumonia is modal pneumonia, is also one of modal infectious disease, so daily the said pneumonia of people mainly refers to the pneumonia that bacterial infection causes.By course of disease classification, pneumonia is divided into acute pneumonia, organizing pneumonia, chronic pneumonia.The clinical symptoms of pneumonia has heating, rapid breathing, lasting dry cough, and dyspnea may have monolateral chest pain, chest pain when deeply breathing and cough, and has expectorant or a large amount of expectorant in a small amount, may contain the blood streak, the visible inflammatory infiltration shade of conducting lung X-ray examination.Child suffers from pneumonia, and symptom is often not obvious, may have slight cough or not cough completely.The most onset of pneumonia is hurried, often suffer from cold drench with rain, fatigue, the inducement such as viral infection, about 1/3 ill before have upper respiratory tract infection.Course of disease 7-10 days.The mainly anti-infective therapy of pneumonia treatment.Current doctor trained in Western medicine, to the treatment of pneumonia, mainly carries out Classification treatment for infected pathogen, as bacterial pneumonia, mycoplasma pneumonia, viral pneumonia etc.Syndrome Differentiation of Chinese Medicine control pneumonia mainly for be not pathogen, but its pathogenesis.Publication No. CN 103550664 A(application number 201310532387.0) Chinese patent literature disclose a kind of Chinese medicine for the treatment of pneumonia, have the Semen Raphani 5 ~ 15 of weight proportion, Pericarpium Citri Reticulatae 8 ~ 17, Fructus Amomi 3 ~ 9, Rhizoma Polygoni Cuspidati 8 ~ 15, Herba Taraxaci 10 ~ 20, Herba Houttuyniae 20 ~ 30, Radix Scutellariae 30 ~ 40, Flos Lonicerae 30 ~ 40, Fructus Forsythiae 10 ~ 18, Herba Schizonepetae 8 ~ 15 to make.Publication No. CN 104352955 A(application number 201410551681.0) Chinese patent literature disclose a kind of Chinese medicine for the treatment of pneumonia, raw material consists of: Rhizoma Coptidis 10-30 part, Radix Scutellariae 10-30 part, Rhizoma Curcumae 5-20 part, Radix Codonopsis 5-20 part, Pericarpium Citri Reticulatae 5-15 part, Indigo Naturalis 5-20 part, Radix Bupleuri 5-20 part, Rhizoma Pinelliae 5-15 part, Poria 5-20 part, Fructus Gardeniae 5-15 part, Herba monochasmatis 5-15 part, Fructus glochidionis puberi(Herba Glochidii Puberi) 5-12 part, Herba Hedyotidis Diffusae 5-20 part, Herba Houttuyniae 5-15 part, Flos Chrysanthemi Indici 5-15 part, Radix Asparagi 5-15 part, Herba Schizonepetae 5-15 part, Flos Lonicerae 5-15 part.Publication No. CN 104189156 A(application number 201410509175.5) Chinese patent literature disclose a kind of formula for pneumonia, comprise Herba Ephedrae 4 ~ 8g; Semen Armeniacae Amarum 8 ~ 12g; Radix Glycyrrhizae Preparata 4 ~ 8g; Gypsum Fibrosum 23 ~ 27g; Flos Lonicerae 18 ~ 22g; Folium Mori 8 ~ 12g.
At present, western medical treatment pneumonia is many can use a large amount of antibiotic, although instant effect, can cause more side effect to patient, therefore, considers from the angle of safety, and the traditional Chinese medical science should as the first-selection of primary disease treatment.But therapeutic effect good traditional Chinese medical science formula is less at present, thus needs the traditional Chinese medical science prescription developing more how more effective treatment pneumonia.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of meticulous compatibility, prepare formula for clearing heat and removing toxicity and the preparation method for the treatment of pneumonia that is superior, that easily take for a long time.
Technical scheme of the present invention is:
The formula for clearing heat and removing toxicity for the treatment of pneumonia, is prepared from primarily of following bulk drugs, is mass parts: Herba Canscorae 12-15, Herba Peristrophis Roxburghianae 3-6, Radix Platycodonis 19-25, buttonbush 12-16, little Herba pteridii latiusculi beanstalk 9-15, Fructus Trichosanthis 16-20, Herba Dracocephali Integrifolii 15-21, Radix Bupleuri 16-25, Radix Stemonae 6-10, Radix Asteris 9-16, Herba Hemipiliae Flabellatae 10-16, Flos Chrysanthemi Indici 8-13, Herba Cirrohopetali Andersonii 9-14, Flos Lonicerae 11-18, Herba Scutellariae indicae 8-16, Fructus Gardeniae 9-15, fishing stalk 7-14.
In preferred scheme, Herba Canscorae 13-14, Herba Peristrophis Roxburghianae 4-5, Radix Platycodonis 21-23, buttonbush 13-15, little Herba pteridii latiusculi beanstalk 11-13, Fructus Trichosanthis 17-19, Herba Dracocephali Integrifolii 17-19, Radix Bupleuri 18-23, Radix Stemonae 7-9, Radix Asteris 11-14, Herba Hemipiliae Flabellatae 12-14, Flos Chrysanthemi Indici 9-12, Herba Cirrohopetali Andersonii 10-13, Flos Lonicerae 13-16, Herba Scutellariae indicae 10-14, Fructus Gardeniae 11-13, fishing stalk 9-12.
Be more preferably, Herba Canscorae 13.5, Herba Peristrophis Roxburghianae 4.5, Radix Platycodonis 22, buttonbush 14, little Herba pteridii latiusculi beanstalk 12, Fructus Trichosanthis 18, Herba Dracocephali Integrifolii 18, Radix Bupleuri 20.5, the Radix Stemonae 8, Radix Asteris 12.5, Herba Hemipiliae Flabellatae 13, Flos Chrysanthemi Indici 10.5, Herba Cirrohopetali Andersonii 11.5, Flos Lonicerae 14.5, Herba Scutellariae indicae 12, Fructus Gardeniae 12, fishing stalk 10.5.
The formula for clearing heat and removing toxicity of described treatment pneumonia, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get the Radix Stemonae to clean, split brokenly, remove carpel, be then dipped in wine, after soaking into, take out, put into frying pan, when slow fire is fried to dark brown, take out, dry in the air cool;
(2) get crystal sugar to be dissolved in water, drench and pick in clean Flos Chrysanthemi Indici, mix thoroughly, moistening, be placed in frying pan, slow fire heats, and fries to time tack-free, takes out, dry in the air cool;
(3) little Herba pteridii latiusculi beanstalk, Radix Asteris and Herba Scutellariae indicae are cleaned, add the washing water of rice of three's quality 5 times, soak after 20 minutes, heating decoction 15 minutes, filters, and collects filtrate, and operation twice, merges twice gained filtrate;
(4) Herba Canscorae, Herba Peristrophis Roxburghianae, Radix Platycodonis, buttonbush, Fructus Trichosanthis, Herba Dracocephali Integrifolii, Radix Bupleuri, Herba Hemipiliae Flabellatae, Herba Cirrohopetali Andersonii, Flos Lonicerae, Fructus Gardeniae and fishing stalk are cleaned, non iron container is put into together with step (1) (2) made crude drug, decoct with water, after water boiling, be adjusted to little fire decoct 20-35 minute (preferred, be adjusted to little fire and decoct 25-30 minute; Be more preferably, be adjusted to little fire and decoct 27 minutes), filter, collect filtrate;
(5) combining step (3) and step (4) gained filtrate, heating is concentrated into 1/2nd of original volume, obtains decoction.
The preparation method of the formula for clearing heat and removing toxicity decoction of described treatment pneumonia, doubly (preferred, the 8.5-9.5 that amount of water is boiled crude drug quality is doubly for the 8-10 that step (4) amount of water is boiled crude drug quality; Be more preferably, amount of water is 9 times of boiled crude drug quality).
The formula for clearing heat and removing toxicity of described treatment pneumonia, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get the Radix Stemonae to clean, split brokenly, remove carpel, be then dipped in wine, after soaking into, take out, put into frying pan, when slow fire is fried to dark brown, take out, dry in the air cool;
(2) get crystal sugar to be dissolved in water, drench and pick in clean Flos Chrysanthemi Indici, mix thoroughly, moistening, be placed in frying pan, slow fire heats, and fries to time tack-free, takes out, dry in the air cool;
(3) little Herba pteridii latiusculi beanstalk, Radix Asteris and Herba Scutellariae indicae are cleaned, add washing water of rice, steeped overnight, take out, dry;
(4) get Herba Canscorae, Herba Peristrophis Roxburghianae, buttonbush, Herba Dracocephali Integrifolii, Herba Hemipiliae Flabellatae, Herba Cirrohopetali Andersonii and fishing stalk to clean, the water of boiled crude drug quality 7 times is added together with step (2) made crude drug, be heated to boiling, a turn little fire decocts 15-25 minute, and (preferred, 17-23 minute decocted by a turn little fire; Be more preferably, turn little fire and decoct 20 minutes), filter, collect filtrate, operation twice, merges twice gained filtrate, and filtrate heating is concentrated into clear paste;
(5) Radix Platycodonis, Fructus Trichosanthis, Radix Bupleuri, Flos Lonicerae and Fructus Gardeniae are cleaned, dry, pulverize and sieve, then add refined honey and step (4) made clear paste, stirring and evenly mixing together with step (1) (3) made crude drug, generally make ball, the heavy 3g of every ball, obtains pill.
The preparation method of the formula for clearing heat and removing toxicity pill of described treatment pneumonia, step (5) was pulverized 100-160 mesh sieve and (preferably, was pulverized 120-140 mesh sieve; Be more preferably, pulverized 130 mesh sieves).
The formula for clearing heat and removing toxicity of described treatment pneumonia, be made into pharmaceutically acceptable soft extract, its preparation method is:
(1) get the Radix Stemonae to clean, split brokenly, remove carpel, be then dipped in wine, after soaking into, take out, put into frying pan, when slow fire is fried to dark brown, take out, dry in the air cool;
(2) get crystal sugar to be dissolved in water, drench and pick in clean Flos Chrysanthemi Indici, mix thoroughly, moistening, be placed in frying pan, slow fire heats, and fries to time tack-free, takes out, dry in the air cool;
(3) little Herba pteridii latiusculi beanstalk, Radix Asteris and Herba Scutellariae indicae are cleaned, add the washing water of rice of three's quality 5 times, soak after 20 minutes, heating decoction 15 minutes, filters, and collects filtrate, and operation twice, merges twice gained filtrate;
(4) Herba Canscorae, Herba Peristrophis Roxburghianae, Radix Platycodonis, buttonbush, Fructus Trichosanthis, Herba Dracocephali Integrifolii, Radix Bupleuri, Herba Hemipiliae Flabellatae, Herba Cirrohopetali Andersonii, Flos Lonicerae, Fructus Gardeniae and fishing stalk are cleaned, non iron container is put into together with step (1) (2) made crude drug, add the soak by water of boiled crude drug quality 9 times, after water boiling, be adjusted to little fire to decoct, filter, collect filtrate;
(5) combining step (3) and step (4) gained filtrate, to be concentrated into relative density be 1.22(60 DEG C in heating) thick paste, then add the mature vinegar of thick paste quality 0.2 times, stir evenly, obtain soft extract.
The preparation method of the formula for clearing heat and removing toxicity soft extract of described treatment pneumonia, step (4) be adjusted to little fire decoct 20-35 minute (preferred, be adjusted to little fire and decoct 25-30 minute; Be more preferably, be adjusted to little fire and decoct 27 minutes).
The formula for clearing heat and removing toxicity of described treatment pneumonia, be made into pharmaceutically acceptable electuary, its preparation method is:
(1) get the Radix Stemonae to clean, split brokenly, remove carpel, be then dipped in wine, after soaking into, take out, put into frying pan, when slow fire is fried to dark brown, take out, dry in the air cool;
(2) get crystal sugar to be dissolved in water, drench and pick in clean Flos Chrysanthemi Indici, mix thoroughly, moistening, be placed in frying pan, slow fire heats, and fries to time tack-free, takes out, dry in the air cool;
(3) little Herba pteridii latiusculi beanstalk, Radix Asteris and Herba Scutellariae indicae are cleaned, add washing water of rice, steeped overnight, take out, dry;
(4) get Herba Canscorae, Herba Peristrophis Roxburghianae, buttonbush, Herba Dracocephali Integrifolii, Herba Hemipiliae Flabellatae, Herba Cirrohopetali Andersonii and fishing stalk to clean, the water of boiled crude drug quality 7 times is added together with step (2) made crude drug, be heated to boiling, a turn little fire decocts 15-25 minute, and (preferred, 17-23 minute decocted by a turn little fire; Be more preferably, turn little fire and decoct 20 minutes), filter, collect filtrate, operation twice, merges twice gained filtrate, and filtrate heating is concentrated into clear paste, spraying dry;
(5) Radix Platycodonis, Fructus Trichosanthis, Radix Bupleuri, Flos Lonicerae and Fructus Gardeniae are cleaned, dry, pulverize and sieve together with step (1) (3) (4) made crude drug and dry thing with sucrose, obtain electuary.
The preparation method of the formula for clearing heat and removing toxicity electuary of described treatment pneumonia, step (5) was pulverized 120-200 mesh sieve and (preferably, was pulverized 140-180 mesh sieve; Be more preferably, pulverized 160 mesh sieves).
Patients with pneumonia lung qi dispersing fever-clearing preparation provided by the invention the present invention according to Chinese medicine principle, scientific formula, taking convenience, without obvious toxic-side effects.In addition, excellent results of the present invention also shows:
1, formula of the present invention has the effects such as effect such as clearing away heat-fire, lung moistening and asthma relieving, relieving cough and resolving phlegm;
2, the present invention is with Chinese medicinal plant material for raw material, and meticulous compatibility, rationally prepares, and made each dosage form is safe and reliable;
3, through clinical verification, products made thereby of the present invention is evident in efficacy, not easily recurs after healing.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1the formula for clearing heat and removing toxicity for the treatment of pneumonia, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Canscorae 12 parts, Herba Peristrophis Roxburghianae 3 parts, Radix Platycodonis 19 parts, buttonbush 12 parts, little Herba pteridii latiusculi beanstalk 9 parts, Fructus Trichosanthis 16 parts, Herba Dracocephali Integrifolii 15 parts, Radix Bupleuri 16 parts, the Radix Stemonae 6 parts, Radix Asteris 9 parts, Herba Hemipiliae Flabellatae 10 parts, Flos Chrysanthemi Indici 8 parts, Herba Cirrohopetali Andersonii 9 parts, Flos Lonicerae 11 parts, Herba Scutellariae indicae 8 parts, Fructus Gardeniae 9 parts, fishing stalk 7 parts.
The preparation method of the formula for clearing heat and removing toxicity decoction of above-mentioned treatment pneumonia is:
(1) get the Radix Stemonae to clean, split brokenly, remove carpel, be then dipped in wine, after soaking into, take out, put into frying pan, when slow fire is fried to dark brown, take out, dry in the air cool;
(2) get crystal sugar to be dissolved in water, drench and pick in clean Flos Chrysanthemi Indici, mix thoroughly, moistening, be placed in frying pan, slow fire heats, and fries to time tack-free, takes out, dry in the air cool;
(3) little Herba pteridii latiusculi beanstalk, Radix Asteris and Herba Scutellariae indicae are cleaned, add the washing water of rice of three's quality 5 times, soak after 20 minutes, heating decoction 15 minutes, filters, and collects filtrate, and operation twice, merges twice gained filtrate;
(4) Herba Canscorae, Herba Peristrophis Roxburghianae, Radix Platycodonis, buttonbush, Fructus Trichosanthis, Herba Dracocephali Integrifolii, Radix Bupleuri, Herba Hemipiliae Flabellatae, Herba Cirrohopetali Andersonii, Flos Lonicerae, Fructus Gardeniae and fishing stalk are cleaned, non iron container is put into together with step (1) (2) made crude drug, add the soak by water of boiled crude drug quality 9 times, after water boiling, be adjusted to little fire and decoct 27 minutes, filter, collect filtrate;
(5) combining step (3) and step (4) gained filtrate, heating is concentrated into 1/2nd of original volume, obtains decoction.
embodiment 2the formula for clearing heat and removing toxicity for the treatment of pneumonia, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Canscorae 15 parts, Herba Peristrophis Roxburghianae 6 parts, Radix Platycodonis 25 parts, buttonbush 16 parts, little Herba pteridii latiusculi beanstalk 15 parts, Fructus Trichosanthis 20 parts, Herba Dracocephali Integrifolii 21 parts, Radix Bupleuri 25 parts, the Radix Stemonae 10 parts, Radix Asteris 16 parts, Herba Hemipiliae Flabellatae 16 parts, Flos Chrysanthemi Indici 13 parts, Herba Cirrohopetali Andersonii 14 parts, Flos Lonicerae 18 parts, Herba Scutellariae indicae 16 parts, Fructus Gardeniae 15 parts, fishing stalk 14 parts.
The preparation method of the formula for clearing heat and removing toxicity pill for the treatment of pneumonia is:
(1) get the Radix Stemonae to clean, split brokenly, remove carpel, be then dipped in wine, after soaking into, take out, put into frying pan, when slow fire is fried to dark brown, take out, dry in the air cool;
(2) get crystal sugar to be dissolved in water, drench and pick in clean Flos Chrysanthemi Indici, mix thoroughly, moistening, be placed in frying pan, slow fire heats, and fries to time tack-free, takes out, dry in the air cool;
(3) little Herba pteridii latiusculi beanstalk, Radix Asteris and Herba Scutellariae indicae are cleaned, add washing water of rice, steeped overnight, take out, dry;
(4) get Herba Canscorae, Herba Peristrophis Roxburghianae, buttonbush, Herba Dracocephali Integrifolii, Herba Hemipiliae Flabellatae, Herba Cirrohopetali Andersonii and fishing stalk to clean, the water of boiled crude drug quality 7 times is added together with step (2) made crude drug, be heated to boiling, turn little fire and decoct 20 minutes, filter, collect filtrate, operate twice, merge twice gained filtrate, filtrate heating is concentrated into clear paste;
(5) Radix Platycodonis, Fructus Trichosanthis, Radix Bupleuri, Flos Lonicerae and Fructus Gardeniae are cleaned, dry, pulverized 130 mesh sieves, then add refined honey and step (4) made clear paste, stirring and evenly mixing together with step (1) (3) made crude drug, generally make ball, the heavy 3g of every ball, obtains pill.
Model case: xxx, man, 55 years old.Main suit: have a bath for 3 days after catching a cold, starts to occur, shiver with cold, cough and high heat, body temperature 39.4 DEG C, expectorant is few, is added with the blood streak, left side chest pain, asthma, poor appetite, fever of the body has antiperspirant not understand, once took febrifuge, therapeutic effect is not obvious, medical check then, upper left lung auscultation has voiced sound, audible and bronchial breathing sound, and hemogram leukocyte count increases, X-ray film checks, upper left lung has the fine and close shadow of large lamellar, is diagnosed as upper left pneumonia.
Take the formula for clearing heat and removing toxicity pill of the present embodiment gained treatment pneumonia, every day 2 times, each 3-5, warm water delivery service, 14 days courses for the treatment of.After taking three days, patient temperature recovers normal, and after taking 5 days, cough disappears, and chest pain alleviates, and appetite takes a turn for the better, and after taking 20 days, patient chest is without sense of discomfort, and check, indices is all normal, and X-ray film has no shade, and patient fully recovers, and follow up a case by regular visits in half a year, patient is not recurred.
embodiment 3the formula for clearing heat and removing toxicity for the treatment of pneumonia, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Canscorae 13 parts, Herba Peristrophis Roxburghianae 4 parts, Radix Platycodonis 21 parts, buttonbush 13 parts, little Herba pteridii latiusculi beanstalk 11 parts, Fructus Trichosanthis 17 parts, Herba Dracocephali Integrifolii 17 parts, Radix Bupleuri 18 parts, the Radix Stemonae 7 parts, Radix Asteris 11 parts, Herba Hemipiliae Flabellatae 12 parts, Flos Chrysanthemi Indici 9 parts, Herba Cirrohopetali Andersonii 10 parts, Flos Lonicerae 13 parts, Herba Scutellariae indicae 10 parts, Fructus Gardeniae 11 parts, fishing stalk 9 parts.
The preparation method of the formula for clearing heat and removing toxicity soft extract for the treatment of pneumonia is:
(1) get the Radix Stemonae to clean, split brokenly, remove carpel, be then dipped in wine, after soaking into, take out, put into frying pan, when slow fire is fried to dark brown, take out, dry in the air cool;
(2) get crystal sugar to be dissolved in water, drench and pick in clean Flos Chrysanthemi Indici, mix thoroughly, moistening, be placed in frying pan, slow fire heats, and fries to time tack-free, takes out, dry in the air cool;
(3) little Herba pteridii latiusculi beanstalk, Radix Asteris and Herba Scutellariae indicae are cleaned, add the washing water of rice of three's quality 5 times, soak after 20 minutes, heating decoction 15 minutes, filters, and collects filtrate, and operation twice, merges twice gained filtrate;
(4) Herba Canscorae, Herba Peristrophis Roxburghianae, Radix Platycodonis, buttonbush, Fructus Trichosanthis, Herba Dracocephali Integrifolii, Radix Bupleuri, Herba Hemipiliae Flabellatae, Herba Cirrohopetali Andersonii, Flos Lonicerae, Fructus Gardeniae and fishing stalk are cleaned, non iron container is put into together with step (1) (2) made crude drug, add the soak by water of boiled crude drug quality 9 times, after water boiling, be adjusted to little fire and decoct 27 minutes, filter, collect filtrate;
(5) combining step (3) and step (4) gained filtrate, to be concentrated into relative density be 1.22(60 DEG C in heating) thick paste, then add the mature vinegar of thick paste quality 0.2 times, stir evenly, obtain soft extract.
Model case: xxx, female, 6 years old.Winter plays in river bank, accidentally falls in icing river, is rescued evening on the same day after debarking, there is the high heat of 40 DEG C, in a certain state of delirium, seek medical advice and be diagnosed as common flu, to bring down a fever process, body temperature fluctuation is between 38-40 DEG C, and seriality is generated heat 2 days, has occurred cough, asthma, uncomfortable in chest, expectorant is thick, xerostomia, the discomforts such as poor appetite, after transfer from one hospital to another and check again, pulmonary hears and moist rale, hemogram checking, total white blood cells obviously increases, increase to master with lymphocyte, X-ray film shows right inflammatory shade and is distributed in right lung section, is diagnosed as right side pneumonia.
Take the formula for clearing heat and removing toxicity soft extract of the present embodiment gained treatment pneumonia, adopt twice daily, each 5-10ml, with warm water delivery service, 14 days courses for the treatment of.Take two days later, patient temperature recovers normal, and after taking 4 days, cough obviously alleviates, and appetite increases, after taking one week, the discomforts such as patient pants, uncomfortable in chest disappear completely, and after adhering to taking a course for the treatment of, patient checks, health indices is all normal, and Rehabilitation, follows up a case by regular visits in 1 year, do not have recurrence.
embodiment 4the formula for clearing heat and removing toxicity for the treatment of pneumonia, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Canscorae 14 parts, Herba Peristrophis Roxburghianae 5 parts, Radix Platycodonis 23 parts, buttonbush 15 parts, little Herba pteridii latiusculi beanstalk 13 parts, Fructus Trichosanthis 19 parts, Herba Dracocephali Integrifolii 19 parts, Radix Bupleuri 23 parts, the Radix Stemonae 9 parts, Radix Asteris 14 parts, Herba Hemipiliae Flabellatae 14 parts, Flos Chrysanthemi Indici 12 parts, Herba Cirrohopetali Andersonii 13 parts, Flos Lonicerae 16 parts, Herba Scutellariae indicae 14 parts, Fructus Gardeniae 13 parts, fishing stalk 12 parts.
The preparation method of the formula for clearing heat and removing toxicity electuary for the treatment of pneumonia is:
(1) get the Radix Stemonae to clean, split brokenly, remove carpel, be then dipped in wine, after soaking into, take out, put into frying pan, when slow fire is fried to dark brown, take out, dry in the air cool;
(2) get crystal sugar to be dissolved in water, drench and pick in clean Flos Chrysanthemi Indici, mix thoroughly, moistening, be placed in frying pan, slow fire heats, and fries to time tack-free, takes out, dry in the air cool;
(3) little Herba pteridii latiusculi beanstalk, Radix Asteris and Herba Scutellariae indicae are cleaned, add washing water of rice, steeped overnight, take out, dry;
(4) get Herba Canscorae, Herba Peristrophis Roxburghianae, buttonbush, Herba Dracocephali Integrifolii, Herba Hemipiliae Flabellatae, Herba Cirrohopetali Andersonii and fishing stalk to clean, the water of boiled crude drug quality 7 times is added together with step (2) made crude drug, be heated to boiling, turn little fire and decoct 20 minutes, filter, collect filtrate, operate twice, merge twice gained filtrate, filtrate heating is concentrated into clear paste, spraying dry;
(5) Radix Platycodonis, Fructus Trichosanthis, Radix Bupleuri, Flos Lonicerae and Fructus Gardeniae are cleaned, dry, pulverized 160 mesh sieves with sucrose together with step (1) (3) (4) made crude drug and dry thing, and obtained electuary.
Model case: xxx, man, 43 years old.Heating body temperature reaches 38.4 DEG C, cough, uncomfortable in chest, asthma flaring of nares, poor appetite, evening exacerbation of symptoms, the breast side of body alters pain, and after taking two days coldrexs, symptom is without any alleviation, medical check, pulmonary's audible and moist rale, there is small pieces segmental even shape consolidation shadow in bilateral pulmonary, and hemogram checking numeration of leukocyte obviously raises, neutrophilic leukocytosis, is diagnosed as double pneumonia.
Take the formula for clearing heat and removing toxicity electuary of the present embodiment gained treatment pneumonia, adopt twice daily, each one bag of 5g, with warm boiled water, 14 days courses for the treatment of.After taking 2 days, temperature recovery is normal, and after taking 5 days, cough disappears, uncomfortable in chest, asthma is alleviated, and after taking a course for the treatment of, malaise symptoms disappears completely, after consolidating a course for the treatment of, and patient's further consultation, x-ray display pulmonary shadow disappears, and patient fully recovers, and follow up a case by regular visits to after half a year, patient has no recurrence.
embodiment 5the formula for clearing heat and removing toxicity for the treatment of pneumonia, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Canscorae 13.5 parts, Herba Peristrophis Roxburghianae 4.5 parts, Radix Platycodonis 22 parts, buttonbush 14 parts, little Herba pteridii latiusculi beanstalk 12 parts, Fructus Trichosanthis 18 parts, Herba Dracocephali Integrifolii 18 parts, Radix Bupleuri 20.5 parts, the Radix Stemonae 8 parts, Radix Asteris 12.5 parts, Herba Hemipiliae Flabellatae 13 parts, Flos Chrysanthemi Indici 10.5 parts, Herba Cirrohopetali Andersonii 11.5 parts, Flos Lonicerae 14.5 parts, Herba Scutellariae indicae 12 parts, Fructus Gardeniae 12 parts, fishing stalk 10.5 parts.
The preparation method of the formula for clearing heat and removing toxicity decoction for the treatment of pneumonia is:
(1) get the Radix Stemonae to clean, split brokenly, remove carpel, be then dipped in wine, after soaking into, take out, put into frying pan, when slow fire is fried to dark brown, take out, dry in the air cool;
(2) get crystal sugar to be dissolved in water, drench and pick in clean Flos Chrysanthemi Indici, mix thoroughly, moistening, be placed in frying pan, slow fire heats, and fries to time tack-free, takes out, dry in the air cool;
(3) little Herba pteridii latiusculi beanstalk, Radix Asteris and Herba Scutellariae indicae are cleaned, add the washing water of rice of three's quality 5 times, soak after 20 minutes, heating decoction 15 minutes, filters, and collects filtrate, and operation twice, merges twice gained filtrate;
(4) Herba Canscorae, Herba Peristrophis Roxburghianae, Radix Platycodonis, buttonbush, Fructus Trichosanthis, Herba Dracocephali Integrifolii, Radix Bupleuri, Herba Hemipiliae Flabellatae, Herba Cirrohopetali Andersonii, Flos Lonicerae, Fructus Gardeniae and fishing stalk are cleaned, non iron container is put into together with step (1) (2) made crude drug, add the soak by water of boiled crude drug quality 9 times, after water boiling, be adjusted to little fire and decoct 27 minutes, filter, collect filtrate;
(5) combining step (3) and step (4) gained filtrate, heating is concentrated into 1/2nd of original volume, obtains decoction.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Herba Canscorae: base is former: be the herb of gentianaceae plant Herba Canscorae.Nature and flavor: micro-sweet, micro-hardship are flat.Gui Jing: lung, spleen, stomach, Liver Channel.Function cures mainly: heat-clearing and toxic substances removing, cough-relieving, pain relieving.For cough due to lung-heat, stomachache, icterohepatitis, venom.
Herba Peristrophis Roxburghianae: base is former: be the herb of acanthaceous plant mountain indigo plant.Nature and flavor: sweet, light, cool.Function cures mainly: clearing away lung-heat to relieve cough, and dissipating blood stasis stops blooding.For hemoptysis of pulmonary tuberculosis, pneumonia, diabetes; External is controlled traumatic injury and is swollen and ache.
Radix Platycodonis: base is former: be the root of Campanulaceae Radix Platycodonis.Nature and flavor: bitter, pungent are flat.Gui Jing: return lung meridian.Function cures mainly: lung qi dispersing, and sore-throat relieving eliminates the phlegm, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Radix Cephalanthi Occidentalis: base is former: be root or the root bark of Maguireothamnus speciosus buttonbush.Nature and flavor: bitter, cool.Gui Jing: lung, large intestine channel.Function cures mainly: clearing away heat and eliminating dampness, dissipating blood stasis for subsidence of swelling.Cure cold heating, cough, laryngopharynx swelling and pain, enteritis, bacillary dysentery, carbuncle, traumatic injury stasis of blood pain.
Little Herba pteridii latiusculi beanstalk: base is former: be the herb of the thin squama Herba pteridii latiusculi in Sinopteridaceae thin squama Cyclosorus plant North China.Nature and flavor: bitter, cold.Function cures mainly: nourishing the lung to arrest cough, clearing away heat and cooling blood.Cure mainly hemoptysis, knife injury.
Fructus Trichosanthis: base is former: be the fruit of cucurbitaceous plant Fructus Trichosanthis.Nature and flavor: cold in nature, sweet in the mouth, micro-hardship.Gui Jing: return lung, stomach, large intestine channel.Function cures mainly: clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, intestine moistening.For cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, and acute mastitis, lung abscess, acute appendicitis swell and ache.
Herba Dracocephali Integrifolii: base is former: be the herb of labiate Herba Dracocephali Integrifolii.Nature and flavor: bitter in the mouth, pungent, property is micro-wet.Function cures mainly: eliminate the phlegm, and cough-relieving is relievingd asthma.Main acute/chronic bronchitis; Bronchial asthma.
Radix Bupleuri: base is former: be the root of samphire Radix Bupleuri, Radix Bupeuri Scorzonerfolii. etc.Nature and flavor: bitter, are slightly cold.Gui Jing: return liver, gallbladder meridian.Function cures mainly: reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.
The Radix Stemonae: base is former: be the tuber of Stemonaceae plant Radix stemonae japonicae, Radix Stemonae or radix stemonae tuberosae etc.Nature and flavor: sweet, bitter, tepor.Gui Jing: return lung meridian.Slightly poisonous.Function cures mainly: nourishing the lung to keep the adverse QI downward cough-relieving, parasite killing.Cough for new chronic cough, pulmonary tuberculosis cough, pertussis; Outer for head louse, body louse, enterobiasis, pudendal pruritus.Honey Radix Stemonae nourishing the lung to arrest cough.For deficiency of YIN chronic cough.
Radix Asteris: base is former: be the root and rhizome of feverfew Radix Asteris.Nature and flavor: pungent, bitter, temperature.Gui Jing: return lung meridian.Function cures mainly: nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm.Breath with cough for abundant expectoration, new chronic cough is coughed, chronic cough hemoptysis.
Herba Hemipiliae Flabellatae: base is former: be the Herb of orchid fan words beak orchid.Nature and flavor: sweet, micro-hardship, flat.Gui Jing: lung meridian.Function cures mainly: nourishing YIN and moistening the lung, tonify deficiency, hemostasis.Main lung-heat type cough, consumptive disease is coughed, deficient impairment caused by overstrain, deficiency-heat, night sweat, lumbago due to renal deficiency, traumatic hemorrhage.
Flos Chrysanthemi Indici: base is former: be the head inflorescence of feverfew Herba Dendranthematis indici, HERBA CHRYSANTHEMI LAVANDULAEFOLII or lavandulaleaf dendranthema herb.Nature and flavor: bitter, pungent, are slightly cold.Gui Jing: return liver, heart channel.Function cures mainly: heat-clearing and toxic substances removing.For furuncle carbuncle, conjunctival congestion and swelling pain, has a headache dizzy.
Herba Cirrohopetali Andersonii: base is former: be the herb of the orchid family volume lobe epidendrum comb cap volume lobe orchid.Nature and flavor: warm, sweet, nontoxic.Function cures mainly: cure mainly rheumatic arthralgia, traumatic injury, and cough is spitted blood, food stagnation, asthenia.
Flos Lonicerae: base is former: be the alabastrum of caprifoliaceae plant Radix Ophiopogonis.Nature and flavor: sweet, cold.Gui Jing: return lung, the heart, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat.
Herba Scutellariae indicae: base is former: be the whole herb with root of labiate Herba Scutellariae indicae.Nature and flavor: pungent, bitter are flat.Gui Jing: " Quanzhou book on Chinese herbal medicine ": " enter the heart, liver, lung three warp." function cures mainly: dispel the wind, and invigorates blood circulation, removing toxic substances, pain relieving.Control traumatic injury, spit blood, hemoptysis, carbuncle, furunculosis, acute throat trouble, toothache.
Fructus Gardeniae: base is former: be the fruit of Maguireothamnus speciosus Fructus Gardeniae.Nature and flavor: bitter, cold.Gui Jing: GUIXIN, lung, tri-jiao channel.Function cures mainly: fruit: pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, jaundice dark coloured urine, blood strangury and dry pain, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles; External treatment bruise pain.
Fishing stalk: base is former: be the herb of goatweed veronicastrum latifoliumYamazaki or thin fringe Herba veronicastri villosuli.Nature and flavor: mildly bitter flavor, cool in nature.Function cures mainly: heat-clearing and toxic substances removing, row water, dissipating blood stasis.Main cough due to lung-heat, dysentery, hepatitis, edema, traumatic injury, venom, burn and scald.
test example 1the clinical practice of the formula for clearing heat and removing toxicity (embodiment 5) of gained treatment pneumonia of the present invention:
In February ,-2014 in April, 2012, from the pneumonia case that hospital accepts for medical treatment, filter out 318 routine patients, wherein women 143 example, male 175 example, age 18-56 year, 34.8 ± 3.2 years old mean age, course of disease 5-10 days.Diagnostic criteria: often demonstrate,prove standard with reference to the pneumonia cough in " Chinese medicine card Standardization of diagnosis and curative effect " (ZY/T001.4-94).1, onset is comparatively anxious, has heating, cough, tachypnea, flaring of nares, the diseases such as rale, or has slight cyanosis; When 2, being in a bad way, dyspnea with rapid and short breath is uneasy, and agitation is not peaceful, and complexion is greyish white, and cyanosis increases the weight of, or high heat is persistent; 3, auscultation of lung: during pulmonary has, fine rales, often accompanies dry rale, or tubular breath sound; 4, hemogram: most of total white blood cells increases, classification neutrophilic leukocytosis.If because of viral infection causer, numeration of leukocyte can reduce, slightly increasing or normal; 5, X-ray examination or take the photograph sheet inspection: pulmonary's exhibit textural increases, disorderly, bright degree reduction, or see strip, mottled confusing shadows, also can be uneven large stretch of shade.
Patient is divided into two groups at random, experimental group 180 example and matched group 138 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference ( p> 0.05), there is comparability.Experimental group takes products obtained therefrom of the present invention, take every day twice (warm), each 150m1-200m1(adjusts to some extent depending on concrete condition), 14 days courses for the treatment of, matched group takes other medicine (conventional medication such as ribavirin tablet, Cefixime tablets, amoxicillin).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.After treating a course for the treatment of, statistics therapeutic outcome.
Curative effect situation criterion: cure: temperature recovery is normal, clinical symptoms and abnormal sign disappear, and surrounding hemogram inspection recovers, and chest X-ray display shade disappears; Effective: temperature recovery is normal, and clinical symptoms obviously alleviates, chest X ray examination display pulmonary shadow has absorption to take a turn for the better; Invalid: body temperature, clinical symptoms are all without obviously alleviating.Result is as shown in table 1.
Table 1 liang group patient treatment outcome
Note: compared with matched group, * p< 0.05
From the therapeutic outcomes of two groups (see table 1), in known experimental group, cure rate is 73.9%, and effective percentage is 23.3%, and the total effective rate of experimental group is 97.2%.In matched group, cure rate is 55.8%, and effective percentage is 18.8%, show that total effective rate is 74.6%, good obviously compared with matched group of the therapeutic effect of experimental group.Statistical analysis, between two groups data there were significant differences ( p< 0.05).
Herba Canscorae in formula of the present invention, Flos Chrysanthemi Indici heat-clearing and toxic substances removing, Herba Peristrophis Roxburghianae clearing away lung-heat to relieve cough, Radix Platycodonis lung qi dispersing sore-throat relieving, Radix Cephalanthi Occidentalis clearing away heat and eliminating dampness, little Herba pteridii latiusculi beanstalk clearing away heat and cooling blood, Fructus Trichosanthis relieving stuffiness of the chest by dispersing aggregation of pathogens, Herba Dracocephali Integrifolii eliminating phlegm and relieving asthma, Radix Bupleuri reconciling superficies and interior, Radix Stemonae nourishing the lung to keep the adverse QI downward, Radix Asteris stopping coughing and removing phlegm, Herba Hemipiliae Flabellatae nourishing YIN and moistening the lung, Flos Lonicerae wind-heat dissipating, Herba Scutellariae indicae wind-expelling pain-stopping, Fructus Gardeniae pathogenic fire purging relieving restlessness, the capable water dissipating blood stasis of fishing stalk, multiple medical material coupling, plays the effects such as clearing away heat-fire, lung moistening and asthma relieving, relieving cough and resolving phlegm altogether.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. treat the formula for clearing heat and removing toxicity of pneumonia, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Herba Canscorae 12-15, Herba Peristrophis Roxburghianae 3-6, Radix Platycodonis 19-25, buttonbush 12-16, little Herba pteridii latiusculi beanstalk 9-15, Fructus Trichosanthis 16-20, Herba Dracocephali Integrifolii 15-21, Radix Bupleuri 16-25, Radix Stemonae 6-10, Radix Asteris 9-16, Herba Hemipiliae Flabellatae 10-16, Flos Chrysanthemi Indici 8-13, Herba Cirrohopetali Andersonii 9-14, Flos Lonicerae 11-18, Herba Scutellariae indicae 8-16, Fructus Gardeniae 9-15, fishing stalk 7-14.
2. the formula for clearing heat and removing toxicity for the treatment of pneumonia as claimed in claim 1, it is characterized in that, Herba Canscorae 13-14, Herba Peristrophis Roxburghianae 4-5, Radix Platycodonis 21-23, buttonbush 13-15, little Herba pteridii latiusculi beanstalk 11-13, Fructus Trichosanthis 17-19, Herba Dracocephali Integrifolii 17-19, Radix Bupleuri 18-23, Radix Stemonae 7-9, Radix Asteris 11-14, Herba Hemipiliae Flabellatae 12-14, Flos Chrysanthemi Indici 9-12, Herba Cirrohopetali Andersonii 10-13, Flos Lonicerae 13-16, Herba Scutellariae indicae 10-14, Fructus Gardeniae 11-13, 9-12 is (preferred for fishing stalk, Herba Canscorae 13.5, Herba Peristrophis Roxburghianae 4.5, Radix Platycodonis 22, buttonbush 14, little Herba pteridii latiusculi beanstalk 12, Fructus Trichosanthis 18, Herba Dracocephali Integrifolii 18, Radix Bupleuri 20.5, the Radix Stemonae 8, Radix Asteris 12.5, Herba Hemipiliae Flabellatae 13, Flos Chrysanthemi Indici 10.5, Herba Cirrohopetali Andersonii 11.5, Flos Lonicerae 14.5, Herba Scutellariae indicae 12, Fructus Gardeniae 12, fishing stalk 10.5).
3. the formula for clearing heat and removing toxicity of the treatment pneumonia as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get the Radix Stemonae to clean, split brokenly, remove carpel, be then dipped in wine, after soaking into, take out, put into frying pan, when slow fire is fried to dark brown, take out, dry in the air cool;
(2) get crystal sugar to be dissolved in water, drench and pick in clean Flos Chrysanthemi Indici, mix thoroughly, moistening, be placed in frying pan, slow fire heats, and fries to time tack-free, takes out, dry in the air cool;
(3) little Herba pteridii latiusculi beanstalk, Radix Asteris and Herba Scutellariae indicae are cleaned, add the washing water of rice of three's quality 5 times, soak after 20 minutes, heating decoction 15 minutes, filters, and collects filtrate, and operation twice, merges twice gained filtrate;
(4) Herba Canscorae, Herba Peristrophis Roxburghianae, Radix Platycodonis, buttonbush, Fructus Trichosanthis, Herba Dracocephali Integrifolii, Radix Bupleuri, Herba Hemipiliae Flabellatae, Herba Cirrohopetali Andersonii, Flos Lonicerae, Fructus Gardeniae and fishing stalk are cleaned, non iron container is put into together with step (1) (2) made crude drug, decoct with water, after water boiling, be adjusted to little fire decoct 20-35 minute (preferred, be adjusted to little fire and decoct 25-30 minute; Be more preferably, be adjusted to little fire and decoct 27 minutes), filter, collect filtrate;
(5) combining step (3) and step (4) gained filtrate, heating is concentrated into 1/2nd of original volume, obtains decoction.
4. the preparation method of the formula for clearing heat and removing toxicity decoction for the treatment of pneumonia as claimed in claim 3, is characterized in that, doubly (preferred, the 8.5-9.5 that amount of water is boiled crude drug quality doubly for the 8-10 that step (4) amount of water is boiled crude drug quality; Be more preferably, amount of water is 9 times of boiled crude drug quality).
5. the formula for clearing heat and removing toxicity of the treatment pneumonia as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get the Radix Stemonae to clean, split brokenly, remove carpel, be then dipped in wine, after soaking into, take out, put into frying pan, when slow fire is fried to dark brown, take out, dry in the air cool;
(2) get crystal sugar to be dissolved in water, drench and pick in clean Flos Chrysanthemi Indici, mix thoroughly, moistening, be placed in frying pan, slow fire heats, and fries to time tack-free, takes out, dry in the air cool;
(3) little Herba pteridii latiusculi beanstalk, Radix Asteris and Herba Scutellariae indicae are cleaned, add washing water of rice, steeped overnight, take out, dry;
(4) get Herba Canscorae, Herba Peristrophis Roxburghianae, buttonbush, Herba Dracocephali Integrifolii, Herba Hemipiliae Flabellatae, Herba Cirrohopetali Andersonii and fishing stalk to clean, the water of boiled crude drug quality 7 times is added together with step (2) made crude drug, be heated to boiling, a turn little fire decocts 15-25 minute, and (preferred, 17-23 minute decocted by a turn little fire; Be more preferably, turn little fire and decoct 20 minutes), filter, collect filtrate, operation twice, merges twice gained filtrate, and filtrate heating is concentrated into clear paste;
(5) Radix Platycodonis, Fructus Trichosanthis, Radix Bupleuri, Flos Lonicerae and Fructus Gardeniae are cleaned, dry, pulverize and sieve, then add refined honey and step (4) made clear paste, stirring and evenly mixing together with step (1) (3) made crude drug, generally make ball, the heavy 3g of every ball, obtains pill.
6. the preparation method of the formula for clearing heat and removing toxicity pill for the treatment of pneumonia as claimed in claim 5, it is characterized in that, step (5) was pulverized 100-160 mesh sieve and (preferably, was pulverized 120-140 mesh sieve; Be more preferably, pulverized 130 mesh sieves).
7. the formula for clearing heat and removing toxicity of the treatment pneumonia as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable soft extract, its preparation method is:
(1) get the Radix Stemonae to clean, split brokenly, remove carpel, be then dipped in wine, after soaking into, take out, put into frying pan, when slow fire is fried to dark brown, take out, dry in the air cool;
(2) get crystal sugar to be dissolved in water, drench and pick in clean Flos Chrysanthemi Indici, mix thoroughly, moistening, be placed in frying pan, slow fire heats, and fries to time tack-free, takes out, dry in the air cool;
(3) little Herba pteridii latiusculi beanstalk, Radix Asteris and Herba Scutellariae indicae are cleaned, add the washing water of rice of three's quality 5 times, soak after 20 minutes, heating decoction 15 minutes, filters, and collects filtrate, and operation twice, merges twice gained filtrate;
(4) Herba Canscorae, Herba Peristrophis Roxburghianae, Radix Platycodonis, buttonbush, Fructus Trichosanthis, Herba Dracocephali Integrifolii, Radix Bupleuri, Herba Hemipiliae Flabellatae, Herba Cirrohopetali Andersonii, Flos Lonicerae, Fructus Gardeniae and fishing stalk are cleaned, non iron container is put into together with step (1) (2) made crude drug, add the soak by water of boiled crude drug quality 9 times, after water boiling, be adjusted to little fire to decoct, filter, collect filtrate;
(5) combining step (3) and step (4) gained filtrate, to be concentrated into relative density be 1.22(60 DEG C in heating) thick paste, then add the mature vinegar of thick paste quality 0.2 times, stir evenly, obtain soft extract.
8. the preparation method of the formula for clearing heat and removing toxicity soft extract for the treatment of pneumonia as claimed in claim 7, is characterized in that, step (4) be adjusted to little fire decoct 20-35 minute (preferred, be adjusted to little fire and decoct 25-30 minute; Be more preferably, be adjusted to little fire and decoct 27 minutes).
9. the formula for clearing heat and removing toxicity of the treatment pneumonia as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable electuary, its preparation method is:
(1) get the Radix Stemonae to clean, split brokenly, remove carpel, be then dipped in wine, after soaking into, take out, put into frying pan, when slow fire is fried to dark brown, take out, dry in the air cool;
(2) get crystal sugar to be dissolved in water, drench and pick in clean Flos Chrysanthemi Indici, mix thoroughly, moistening, be placed in frying pan, slow fire heats, and fries to time tack-free, takes out, dry in the air cool;
(3) little Herba pteridii latiusculi beanstalk, Radix Asteris and Herba Scutellariae indicae are cleaned, add washing water of rice, steeped overnight, take out, dry;
(4) get Herba Canscorae, Herba Peristrophis Roxburghianae, buttonbush, Herba Dracocephali Integrifolii, Herba Hemipiliae Flabellatae, Herba Cirrohopetali Andersonii and fishing stalk to clean, the water of boiled crude drug quality 7 times is added together with step (2) made crude drug, be heated to boiling, a turn little fire decocts 15-25 minute, and (preferred, 17-23 minute decocted by a turn little fire; Be more preferably, turn little fire and decoct 20 minutes), filter, collect filtrate, operation twice, merges twice gained filtrate, and filtrate heating is concentrated into clear paste, spraying dry;
(5) Radix Platycodonis, Fructus Trichosanthis, Radix Bupleuri, Flos Lonicerae and Fructus Gardeniae are cleaned, dry, pulverize and sieve together with step (1) (3) (4) made crude drug and dry thing with sucrose, obtain electuary.
10. the preparation method of the formula for clearing heat and removing toxicity electuary for the treatment of pneumonia as claimed in claim 9, it is characterized in that, step (5) was pulverized 120-200 mesh sieve and (preferably, was pulverized 140-180 mesh sieve; Be more preferably, pulverized 160 mesh sieves).
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