CN104688980A - Medicine for treating burns and scalds and trauma and preparation method of medicine - Google Patents
Medicine for treating burns and scalds and trauma and preparation method of medicine Download PDFInfo
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Abstract
The invention provides a medicine for treating burns and scalds and trauma and a preparation method of the medicine. The medicine is prepared from the following traditional Chinese medicinal materials in parts by weight: 5-15 parts of arnebia euchroma, 5-15 parts of scutellaria baicalensis, 2-8 parts of raw sanguisorba officinalis and 2-8 parts of dragon's blood. The medicine for treating burns and scalds and trauma is capable of treating burns and scalds, and treating pyogenic infection and other open trauma and malignant carbuncles, is capable of rapidly relieving pain for burns and scalds. The thrill to the wound can be reduced; the wound can be rapidly repaired; outflow of percolate is relieved; and the pain threshold and pain time of patients can be effectively and rapidly reduced.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be particularly a kind ofly used for the treatment of burn and scald medicine injuring wound and preparation method thereof.
Background technology
Burn and scald is common clinical, frequently-occurring disease, the pain unbearably patient caused with it, the easy infection of burn wound and because of infect bring to patient body a series of physiology, the change of pathology and serious consequence, trouble the world of medicine always.The method of current treatment burn and scald mistake is as follows:
(1) with tap water, immersion, ice compress wound
Learned all knowing of physics, cold and hot meeting can absorb heat fast, lowers the temperature, but for just being burnt, scalding, does is it correct for directly rinsing with raw cooling water (RCW) or soak? the traditional Chinese medical science thinks that this is wrong, and after burn and scald, skin exists a large amount of pyretic toxicity, with cold water flush, immersion, cold and hot punching mutually can cause invading in pyretic toxicity, make pyretic toxicity remain in wound in a large number, cause wound in the future to recover slowly, even not heal, repeatedly get blister after healing, again fester.More serious burn and scald more can not contact raw cooling water (RCW).
(2) bind up a wound
General burn and scald should not be wrapped up, and wrapping easily makes wound recover slowly, and through clinical observation: use same Drug therapy, bind up a wound, two degree of scalds often also need more than one month time to heal.And exposure treatment, two degree of scalds can heal in 1 ~ 3 week, and the better effects if of healing, and skin is smooth without scar.Bandaging method for treating also has another drawback, allows the wounded bear bitter sorrow exactly, changes dressings each time and all will disassemble wrapping, repeatedly damage wound, very easily stay scar.
(3) with povidone iodine, ethanol, hydrogen peroxide etc. wound cleaned and sterilize
Damaged skin cell mortality after scalding, being more the major injury being subject to high temperature, is definitely can not be subject to strong impulse again.And these disinfectant above-mentioned have strong impulse effect to wound cells, more many cells can be caused after using downright bad, not only do not have due antiinflammation, can the condition of the injury be deepened on the contrary, run counter to desire.
(4) excessive use antibiotic antiinflammatory
Usually general burn and scald does not need to use antibiotic medicine, does not more need antiinflammatory of infusing.According to correct method nuring wound, generally can not inflammation, do not need to use antibiotic antiinflammatory.
What need antiinflammatory is that whole body large area is scalded, such as whole body more than 20 ~ 30% Area Burn, scald, and such large area is scalded and easily made human body dehydration too much, fluid electrolyte is unbalance, causes people to have a fever, wound infection, so must do infection process, transfusion ensures the stable of physical condition.
(5) the oils medicine that adopts covers more at present, not easily absorbs, and contact wound surface causes sharp ache.
Summary of the invention
For solving the deficiency of above-mentioned treatment burn and scald, the invention provides and a kind ofly be used for the treatment of burn and scald medicine injuring wound and preparation method thereof, this medicine can reduce stimulation, the fast wound repairing to wound surface and effectively protect from infection.
Technical scheme of the present invention is achieved in that
Treating the medicine that burn and scald injures wound, is obtained by the Chinese crude drug of following weight parts: Radix Arnebiae (Radix Lithospermi) 5 ~ 15 weight portion, Radix Scutellariae 5 ~ 15 weight portion, Radix Sangusorbae 2 ~ 8 weight portion, Sanguis Draxonis 2 ~ 8 weight portion.
Wherein, preferably, a kind ofly treating the medicine that burn and scald injures wound, is obtained by the Chinese crude drug of following weight parts: Radix Arnebiae (Radix Lithospermi) 8 ~ 12 weight portion, Radix Scutellariae 8 ~ 12 weight portion, Radix Sangusorbae 4 ~ 6 weight portion, Sanguis Draxonis 4 ~ 6 weight portion.
Wherein, preferably, a kind ofly treating the medicine that burn and scald injures wound, is obtained by the Chinese crude drug of following weight parts: Radix Arnebiae (Radix Lithospermi) 10 weight portion, Radix Scutellariae 10 weight portion, Radix Sangusorbae 5 weight portion, Sanguis Draxonis 5 weight portion.
For solving the deficiency of above-mentioned treatment burn and scald, the present invention also provides a kind of and treats the preparation method that burn and scald injures traumatic thing, comprises the following steps:
(1) respectively Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Sangusorbae and Sanguis Draxonis are adopted super-micro wall-broken crushing technology, be ground into the fine powder of more than 380 orders;
(2) take Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Sangusorbae and fine powder of dragons blood respectively by above-mentioned weight portion, mix homogeneously, add 75% alcohol reflux 1 ~ 3 hour of 15 ~ 25 times amount, filter, concentrated, make the weight of concentrated solution be 3 ~ 5 times of Chinese crude drug weight portion.
The flavour of a drug of each Chinese crude drug return through and effect as follows:
Radix Arnebiae (Radix Lithospermi)
[meridian distribution of property and flavor]: sweet, cold.GUIXIN, Liver Channel.
[effect]: removing heat from blood and promoting blood circulation, removing toxic substances rash.(this product has removing toxic substances, antiinflammatory, antibacterial action containing shikonin, all has inhibitory action to staphylococcus aureus, escherichia coli, dysentery bacterium etc.).
Radix Scutellariae
[meridian distribution of property and flavor]: bitter, cold.Return lung, stomach, gallbladder, large intestine channel.
[effect]: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.(this product, containing baicalin, baicalin etc., has broad-spectrum antibacterial action, all has inhibitory action to Bacillus typhi, dysentery bacterium, bacillus pyocyaneus, bordetella pertussis, staphylococcus, streptococcus, Diplococcus pneumoniae, meningococcus.Separately there is antipyretic, analgesia, blood pressure lowering, diuresis, protect the liver and the effect such as antioxidation, antiinflammatory, antiallergic action).
Radix Sangusorbae
[meridian distribution of property and flavor]: bitter, sour, is slightly cold.Return liver, stomach, large intestine channel.
[effect]: cooling blood for hemostasis, removing toxic substances sore.(this product is containing ziyuglycoside, sanguisorbin, tannin etc., can clotting time be shortened, and have anastalsis, have inhibitory action to staphylococcus aureus, bacillus pyocyaneus, Bacillus typhi, tubercule bacillus, wound fluid can be made to reduce, have slight decompressing effect).
Sanguis Draxonis
[meridian distribution of property and flavor]: sweet, salty, flat.Return Liver Channel.
[effect]: invigorate blood circulation and cure the wound, hemostasia and promoting granulation.(this product main component is dracorhodin, can anticoagulant, prevents thrombosis, has inhibitory action in various degree, improve microcirculation, and have anastalsis various pathogens).
Beneficial effect of the present invention:
1. can reduce the stimulation to wound surface, quick wound repairing, alleviates the outflow of transudate, alleviates pain threshold and the pain time of patient fast and effectively.
2. effectively protect from infection.
3. wound surface skin growth is even, not easily scar.
4. medical expense significantly reduces, and alleviates patient economy burden.
Detailed description of the invention
Be clearly and completely described the technical scheme in the embodiment of the present invention below, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making other embodiments all obtained under creative work prerequisite, belong to the scope of protection of the invention.
Treating the medicine that burn and scald injures wound, is obtained by the Chinese crude drug of following weight parts: Radix Arnebiae (Radix Lithospermi) 5 ~ 15 weight portion, Radix Scutellariae 5 ~ 15 weight portion, Radix Sangusorbae 2 ~ 8 weight portion, Sanguis Draxonis 2 ~ 8 weight portion.
Treat the preparation method that burn and scald injures traumatic thing, comprise the following steps:
(1) respectively Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Sangusorbae and Sanguis Draxonis are adopted super-micro wall-broken crushing technology, be ground into the fine powder of more than 380 orders;
(2) take Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Sangusorbae and fine powder of dragons blood respectively by weight, mix homogeneously, add 75% alcohol reflux 1 ~ 3 hour of 15 ~ 25 times amount, filter, concentrated, make the weight of concentrated solution be 3 ~ 5 times of Chinese crude drug weight.
Embodiment 1
The present embodiment provides a kind of and treats the medicine that burn and scald injures wound, is obtained by the Chinese crude drug of following weight parts: Radix Arnebiae (Radix Lithospermi) 10 weight portion, Radix Scutellariae 10 weight portion, Radix Sangusorbae 5 weight portion, Sanguis Draxonis 5 weight portion.
The present embodiment also provides a kind of and treats the preparation method that burn and scald injures traumatic thing, comprises the following steps:
(1) respectively Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Sangusorbae and Sanguis Draxonis are adopted super-micro wall-broken crushing technology, be ground into the fine powder of more than 380 orders;
(2) fine powder of following weight portion is taken respectively: Radix Arnebiae (Radix Lithospermi) 10 weight portion, Radix Scutellariae 10 weight portion, Radix Sangusorbae 5 weight portion, Sanguis Draxonis 5 weight portion, mix homogeneously, add 75% alcohol reflux 2 hours of 20 times amount, filter, concentrated, make the weight of concentrated solution be 4 times of Chinese crude drug weight, namely obtain the concentrated solution of 120 weight portions.
Embodiment 2
The present embodiment provides a kind of and treats the medicine that burn and scald injures wound, is obtained by the Chinese crude drug of following weight parts: Radix Arnebiae (Radix Lithospermi) 5 weight portion, Radix Scutellariae 15 weight portion, Radix Sangusorbae 2 weight portion, Sanguis Draxonis 8 weight portion.
The present embodiment also provides a kind of and treats the preparation method that burn and scald injures traumatic thing, comprises the following steps:
(1) respectively Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Sangusorbae and Sanguis Draxonis are adopted super-micro wall-broken crushing technology, be ground into the fine powder of more than 380 orders;
(2) fine powder of following weight portion is taken respectively: Radix Arnebiae (Radix Lithospermi) 5 weight portion, Radix Scutellariae 15 weight portion, Radix Sangusorbae 2 weight portion, Sanguis Draxonis 8 weight portion, mix homogeneously, add 75% alcohol reflux 3 hours of 15 times amount, filter, concentrated, make the weight of concentrated solution be 3 times of Chinese crude drug weight, namely obtain the concentrated solution of 90 weight portions.
Embodiment 3
The present embodiment provides a kind of and treats the medicine that burn and scald injures wound, is obtained by the Chinese crude drug of following weight parts: Radix Arnebiae (Radix Lithospermi) 15 weight portion, Radix Scutellariae 5 weight portion, Radix Sangusorbae 8 weight portion, Sanguis Draxonis 2 weight portion.
The present embodiment also provides a kind of and treats the preparation method that burn and scald injures traumatic thing, comprises the following steps:
(1) respectively Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Sangusorbae and Sanguis Draxonis are adopted super-micro wall-broken crushing technology, be ground into the fine powder of more than 380 orders;
(2) fine powder of following weight portion is taken respectively: Radix Arnebiae (Radix Lithospermi) 15 weight portion, Radix Scutellariae 5 weight portion, Radix Sangusorbae 8 weight portion, Sanguis Draxonis 2 weight portion, mix homogeneously, add 75% alcohol reflux 1 hour of 25 times amount, filter, concentrated, make the weight of concentrated solution be 5 times of Chinese crude drug weight, namely obtain the concentrated solution of 150 weight portions.
Embodiment 4
The present embodiment provides a kind of and treats the medicine that burn and scald injures wound, is obtained by the Chinese crude drug of following weight parts: Radix Arnebiae (Radix Lithospermi) 8 weight portion, Radix Scutellariae 12 weight portion, Radix Sangusorbae 4 weight portion, Sanguis Draxonis 6 weight portion.
The present embodiment also provides a kind of and treats the preparation method that burn and scald injures traumatic thing, comprises the following steps:
(1) respectively Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Sangusorbae and Sanguis Draxonis are adopted super-micro wall-broken crushing technology, be ground into the fine powder of more than 380 orders;
(2) fine powder of following weight portion is taken respectively: Radix Arnebiae (Radix Lithospermi) 8 weight portion, Radix Scutellariae 12 weight portion, Radix Sangusorbae 4 weight portion, Sanguis Draxonis 6 weight portion, mix homogeneously, add 75% alcohol reflux 2 hours of 20 times amount, filter, concentrated, make the weight of concentrated solution be 4 times of Chinese crude drug weight, namely obtain the concentrated solution of 120 weight portions.
Embodiment 5
The present embodiment provides a kind of and treats the medicine that burn and scald injures wound, is obtained by the Chinese crude drug of following weight parts: Radix Arnebiae (Radix Lithospermi) 12 weight portion, Radix Scutellariae 8 weight portion, Radix Sangusorbae 6 weight portion, Sanguis Draxonis 4 weight portion.
The present embodiment also provides a kind of and treats the preparation method that burn and scald injures traumatic thing, comprises the following steps:
(1) respectively Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Sangusorbae and Sanguis Draxonis are adopted super-micro wall-broken crushing technology, be ground into the fine powder of more than 380 orders;
(2) fine powder of following weight portion is taken respectively: Radix Arnebiae (Radix Lithospermi) 12 weight portion, Radix Scutellariae 8 weight portion, Radix Sangusorbae 6 weight portion, Sanguis Draxonis 4 weight portion, mix homogeneously, add 75% alcohol reflux 2 hours of 20 times amount, filter, concentrated, make the weight of concentrated solution be 4 times of Chinese crude drug weight, namely obtain the concentrated solution of 120 weight portions.
The medicine of the treatment empyrosis that above-mentioned five embodiments provide can produce following technique effect:
Not only can treat burn and scald, all right therapeutic pyogenic infection, and other open wound, pernicious skin infection, can also be used for the quickly alleviating pain of empyrosis simultaneously.Use latter 10 minutes, wound pain obviously alleviates, and within 1-3 hour, wound fluid obviously reduces, and within 6-12 hour, wound surface forms protective layer, and skin histology grows reparation gradually, and use sag of protecting coating in about 7 days, wound surface is repaired completely.Because there being the formation of protecting wound surface layer, making wound surface skin growth even, not easily forming cicatrix.
In order to ensure Drug safety of the present invention and curative effect, medicine of the present invention is used to carry out observation of curative effect to treatment burn clinically.
1. patient profiles
Select 72 routine fire victims, wherein male 38 people, women 34 people, maximum burn surface area 90%, minimum area 4%;
2, diagnostic criteria
" new Chinese medicine guideline of clinical investigations " that observed patient promulgates with reference to Ministry of Public Health is diagnostic criteria.
The degree of depth:
I degree (erythema): mild redness burning pain, hyperesthesia, epidermis is dry;
II degree (blister):
Light degree Ⅱ: severe pain, hyperesthesia, skin lesion, temperature increases blister, and substrate is moist, and in evenly red, edema is obvious;
Dark II degree: insensitive, have blister, bed moist is pale, and have little petechia, edema is obvious;
III degree (eschar): anesthesia, inelastic, hard as leather sample, white, the sallow or carbonization of wax, after dry, visible venae subcutaneae blocks as dendroid;
Area: with palm test and Chinese rule of Nine estimation.
3, Therapeutic Method
In time empyrosis wound surface is cleaned out, wound surface extracting solution evenly sprayed with medical apours mists spray gun, every day 6-10 time.
4, curative effect determinate standard
Clinical recovery: heal in skin ulcer face, General Symptoms disappears;
Effective: II degree of total skin ulcer face healing more than 90%, or III degree of total skin ulcer face healing more than 50%, General Symptoms disappears;
Effective: II degree of total skin ulcer face healing more than 50%, or III degree of total skin ulcer face healing more than 30%, General Symptoms disappears;
Invalid: not reach effective standard, skin ulcer face is infected and is failed to control.
5, therapeutic outcome
Recovery from illness 30 example in 72 routine patients, cure rate 41.7%; Effective 20 examples, obvious effective rate 27.8%; Effective 15 examples, effective percentage 20.8%; Total effective rate reaches 90.3%; Invalid 7 examples, inefficiency is 9.7%
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (4)
1. treating the medicine that burn and scald injures wound, it is characterized in that, is obtained by the Chinese crude drug of following weight parts: Radix Arnebiae (Radix Lithospermi) 5 ~ 15 weight portion, Radix Scutellariae 5 ~ 15 weight portion, Radix Sangusorbae 2 ~ 8 weight portion, Sanguis Draxonis 2 ~ 8 weight portion.
2. treating the medicine that burn and scald injures wound, it is characterized in that, is obtained by the Chinese crude drug of following weight parts: Radix Arnebiae (Radix Lithospermi) 8 ~ 12 weight portion, Radix Scutellariae 8 ~ 12 weight portion, Radix Sangusorbae 4 ~ 6 weight portion, Sanguis Draxonis 4 ~ 6 weight portion.
3. treating the medicine that burn and scald injures wound, it is characterized in that, is obtained by the Chinese crude drug of following weight parts: Radix Arnebiae (Radix Lithospermi) 10 weight portion, Radix Scutellariae 10 weight portion, Radix Sangusorbae 5 weight portion, Sanguis Draxonis 5 weight portion.
4. the treatment burn and scald described in any one of claims 1 to 3 injures a preparation method for traumatic thing, it is characterized in that, comprises the following steps:
(1) respectively Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Sangusorbae and Sanguis Draxonis are adopted super-micro wall-broken crushing technology, be ground into the fine powder of more than 380 orders;
(2) take Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Sangusorbae and fine powder of dragons blood respectively by weight, mix homogeneously, add 75% alcohol reflux 1 ~ 3 hour of 15 ~ 25 times amount, filter, concentrated, make the weight of concentrated solution be 3 ~ 5 times of Chinese crude drug weight.
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| CN201510094610.7A CN104688980A (en) | 2015-03-03 | 2015-03-03 | Medicine for treating burns and scalds and trauma and preparation method of medicine |
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| CN201510094610.7A CN104688980A (en) | 2015-03-03 | 2015-03-03 | Medicine for treating burns and scalds and trauma and preparation method of medicine |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1498628A (en) * | 2002-11-05 | 2004-05-26 | 潘福宽 | External burn cream |
| CN1709435A (en) * | 2005-07-05 | 2005-12-21 | 北京阜康仁生物制药科技有限公司 | Gel formulation for treatig traumatic injury and its preparing method |
| CN102631440A (en) * | 2012-04-16 | 2012-08-15 | 荣昌制药(淄博)有限公司 | External traditional Chinese medicine preparation for treating burns and scalds as well as preparation method and quality detection method of preparation |
-
2015
- 2015-03-03 CN CN201510094610.7A patent/CN104688980A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1498628A (en) * | 2002-11-05 | 2004-05-26 | 潘福宽 | External burn cream |
| CN1709435A (en) * | 2005-07-05 | 2005-12-21 | 北京阜康仁生物制药科技有限公司 | Gel formulation for treatig traumatic injury and its preparing method |
| CN102631440A (en) * | 2012-04-16 | 2012-08-15 | 荣昌制药(淄博)有限公司 | External traditional Chinese medicine preparation for treating burns and scalds as well as preparation method and quality detection method of preparation |
Non-Patent Citations (1)
| Title |
|---|
| 琚玮等: "《新全实用中成药手册》", 30 June 2004 * |
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