CN106267131A - Ointment for treating burn and scald and preparation method thereof - Google Patents
Ointment for treating burn and scald and preparation method thereof Download PDFInfo
- Publication number
- CN106267131A CN106267131A CN201610895328.3A CN201610895328A CN106267131A CN 106267131 A CN106267131 A CN 106267131A CN 201610895328 A CN201610895328 A CN 201610895328A CN 106267131 A CN106267131 A CN 106267131A
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- China
- Prior art keywords
- scald
- ointment
- water
- angelicae sinensis
- rhizoma zingiberis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
Abstract
The invention discloses a kind of ointment for treating burn and scald and preparation method thereof, described ointment for treating burn and scald is prepared from by Cortex Pini, Borneolum Syntheticum, Radix Angelicae Sinensis, Radix Notoginseng, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Oleum sesami and water, and concrete preparation process is as follows: one, Cortex Pini, Borneolum Syntheticum, Radix Angelicae Sinensis, Radix Notoginseng, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens clear water are cleaned, dry standby；Two, add water to clean porcelain heats；Three, Cortex Pini is put in porcelain, be heated to water boiling；Four, Borneolum Syntheticum, Radix Angelicae Sinensis, Radix Notoginseng, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens are sequentially placed in porcelain and boil, be then down to room temperature；Five, filter, filtrate adds sesame oil stirring and becomes paste.Compatibility of the present invention is reasonable, each prescription composition Synergistic, directly acts on skin, by the Transdermal absorption of medicine, reaches to treat the purpose of burn and scald.After patient smears this cream, causalgia sense alleviates immediately, light, moderate burned patient if not allergic constitution, affected part preventing from scar, have evident in efficacy, instant effect, relieving the pain property strong, short treating period, the feature that has no side effect.
Description
Technical field
The invention belongs to pharmaceutical technology field, relate to a kind of ointment treating burn and scald and preparation method thereof.
Background technology
Burn and scald is unexpected injury common in life, and boiling water, rolling medicated porridge, deep fat, the burn and scald of heat steam often can occur
Thing.For burn and scald, divide into by the order of severity: slight, moderate and severe burn and scald；Divide into by the degree of depth: once burn and scald
Wound, two degree of burn and scald, three degree of burn and scald.Burn and scald easily causes cutaneous lesion body fluid to ooze out, antibacterial infect, fester do not heal,
Leave over cicatrix, even cause hyperpyrexia, shock, threat to life.
The external used medicine for the treatment of burn and scald is varied at present, and therapeutic effect is also each has something to recommend him, but sees on the whole, generally
There is treatment cycle length, slow, the easy infection of taking effect, easily stay the shortcomings such as cicatrix, increase the weight of the misery of patient.
Summary of the invention
It is an object of the invention to provide a kind of short treating period, instant effect, the most susceptible ointment for treating burn and scald and preparation method thereof.
It is an object of the invention to be achieved through the following technical solutions:
A kind of ointment for treating burn and scald, by 100～200g Cortex Pini, 100～200g Borneolum Syntheticum, 100～200g Radix Angelicae Sinensis, 100～200g
Radix Notoginseng, 100～200g Folium Artemisiae Argyi, 100～200g Rhizoma Zingiberis Recens, 200～300g Oleum sesami and 800～1200g water are prepared from.
The preparation method of a kind of above-mentioned ointment for treating burn and scald, comprises the following steps:
One, Cortex Pini, Borneolum Syntheticum, Radix Angelicae Sinensis, Radix Notoginseng, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens clear water are cleaned, dry standby；
Two, add water to, in clean porcelain, be heated to 60～80 DEG C；
Three, Cortex Pini is put in porcelain, be heated to water boiling；
Four, Borneolum Syntheticum, Radix Angelicae Sinensis, Radix Notoginseng, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens are sequentially placed in porcelain and boil 10～20min, be then down to room
Temperature；
Five, filter, filtrate adds sesame oil stirring and becomes paste.
Effect raw materials used in burn-scald medicine of the present invention is as follows:
Cortex Pini: bitter, puckery, temperature, return lung, large intestine channel, there is effect of convergence, granulation promoting；
Borneolum Syntheticum: arduous, cool, enter the heart, Liver Channel, there is refreshment of having one's ideas straightened out, effect of the scattered poison of heat clearing away；
Radix Angelicae Sinensis: sweet, pungent, warm, returns liver, the heart, spleen channel, have enrich blood, invigorate blood circulation, effect of menstruction regulating and pain relieving；
Radix Notoginseng: hardship sweet, micro-, temperature, return liver, stomach warp, there is dissipating blood stasis hemostasis, effect of subduing swelling and relieving pain；
Folium Artemisiae Argyi: pungent, bitter, temperature, return liver,spleen,kidney warp, there is warming the meridian for stopping bleeding, dispersing cold for relieving pain, effect of external removing dampness to relieve itching；
Rhizoma Zingiberis Recens: there is antipyretic, antibacterial, the effect of antiinflammatory.
Compatibility of the present invention is reasonable, each prescription composition Synergistic, directly acts on skin, by the Transdermal absorption of medicine,
Reach to treat the purpose of burn and scald.After patient smears this cream, causalgia sense alleviates immediately, and light, moderate burned patient is if not mistake
Quick body constitution, affected part preventing from scar, have that evident in efficacy, instant effect, relieving the pain property be strong, short treating period, the feature that has no side effect.
Accompanying drawing explanation
Fig. 1 is the therapeutic effect figure scalded first day；
Fig. 2 is the therapeutic effect figure scalded second day；
Fig. 3 is the therapeutic effect figure scalded the 3rd day；
Fig. 4 is the therapeutic effect figure scalded the 4th day；
Fig. 5 is the therapeutic effect figure scalded the 5th day；
Fig. 6 is the therapeutic effect figure scalded the 6th day；
Fig. 7 is the therapeutic effect figure scalded the 8th day.
Detailed description of the invention
Below in conjunction with the accompanying drawings technical scheme is further described, but is not limited thereto, every to this
Inventive technique scheme is modified or equivalent, without deviating from the spirit and scope of technical solution of the present invention, all should contain
In protection scope of the present invention.
Embodiment 1:
The ointment for treating burn and scald of the present embodiment by 150g Cortex Pini, 120g Borneolum Syntheticum, 180g Radix Angelicae Sinensis, 150g Radix Notoginseng, 120g Folium Artemisiae Argyi,
150g Rhizoma Zingiberis Recens, 250g Oleum sesami and 1000g water are prepared from, and concrete preparation process is as follows:
One, Cortex Pini, Borneolum Syntheticum, Radix Angelicae Sinensis, Radix Notoginseng, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens clear water are cleaned, dry standby；
Two, 1000g water is added in clean porcelain, be heated to 80 DEG C；
Three, 150g Cortex Pini is put in porcelain, be heated to water boiling；
Four, 120g Borneolum Syntheticum, 180g Radix Angelicae Sinensis, 150g Radix Notoginseng, 120g Folium Artemisiae Argyi, 150g Rhizoma Zingiberis Recens are sequentially placed in porcelain and boil
15min, is then down to room temperature；
Five, filter, filtrate adds 250g sesame oil stirring and becomes paste.
Embodiment 2:
As different from Example 1, ointment for treating burn and scald is by 120g Cortex Pini, 150g Borneolum Syntheticum, 150g Radix Angelicae Sinensis, 120g for the present embodiment
Radix Notoginseng, 150g Folium Artemisiae Argyi, 180g Rhizoma Zingiberis Recens, 220g Oleum sesami and 900g water are prepared from.
Embodiment 3:
As different from Example 1, ointment for treating burn and scald is by 180g Cortex Pini, 180g Borneolum Syntheticum, 120g Radix Angelicae Sinensis, 180g for the present embodiment
Radix Notoginseng, 180g Folium Artemisiae Argyi, 120g Rhizoma Zingiberis Recens, 280g Oleum sesami and 1000g water are prepared from.
Clinical trial:
(1) subjects: 100 example burned patients, wherein: male 65 examples, female 35 example, the oldest person 78 years old, reckling 5
In year, patient's burn and scald degree differs, wherein: spend 38 examples, light degree Ⅱ 30 example, deep II degree of 32 example.
(2) diagnostic criteria:
I degree: the reddest, swollen, hot, bitterly, hyperesthesia, not get blister, epidermis is dried；
Light degree Ⅱ: severe pain, hyperesthesia, temperature increases, and has water scar, and substrate is moist, and in the most red, water scar is obvious.
Deep II degree: hypalgesia, water scar is with little or no, throws off epidermis, and substrate drying is pale, has little petechia, and edema is bright
Aobvious.
(3) Therapeutic Method:
100 example burned patients are divided into treatment group and matched group by the principle using parallel control, often organize 50 example patients.Warp
Statistical analysis, two groups of Genders, age, courses of disease, grading etc. there was no significant difference (P ＞ 0.05), has comparability.
Treatment group: the ointment for treating burn and scald being stained with embodiment 1 with medical cotton stick is directly applied to injury, every day 2 times, and the morning and evening is each the most once, 3
It is a course for the treatment of.If the most coated other drug, after being cleaned injury with light salt brine, repaste this cream.
Matched group: be coated with and use conventional medicine MEIBAO SHIRUN SHAOSHANG GAO, method shown in by specification uses.
(4) treatment standard
Cure: wound surface heals completely, and skin lesion all disappears；
Effective: symptom substantially alleviates, skin lesion goes down > 30%；
Invalid: symptom alleviates or skin lesion goes down < 30%.
(5) therapeutic outcome:
Treatment group compares with matched group general curative effect, and its result is: treatment group cures 38 examples, effective 12 examples, total effective rate
100%；Treatment of control group group cures 25 examples, effective 15 examples, invalid 10 examples, total effective rate 80%, and two groups are compared curative effect and have significantly
Difference.
Model case:
Certain man, 32 years old, scalding leg, scalding area reached about 43%, has many blisters, has an intense pain, at blister
Surface applies the ointment for treating burn and scald of the present invention, pain relief after 10 minutes, does not aches after 30 minutes, and after 12 hours, wound surface redness is bright
Show and disappear, vesicle atrophy, within 6 days, it is clearly better, recovery from illness in 7-10 days, therapeutic effect is as shown in Fig. 1～7.
Claims (5)
1. an ointment for treating burn and scald, it is characterised in that described ointment for treating burn and scald by 100～200g Cortex Pini, 100～200g Borneolum Syntheticum, 100
～200g Radix Angelicae Sinensis, 100～200g Radix Notoginseng, 100～200g Folium Artemisiae Argyi, 100～200g Rhizoma Zingiberis Recens, 200～300g Oleum sesami and 800～
1200g water is prepared from.
Ointment for treating burn and scald the most according to claim 1, it is characterised in that described ointment for treating burn and scald is by 150g Cortex Pini, 120g ice
Sheet, 180g Radix Angelicae Sinensis, 150g Radix Notoginseng, 120g Folium Artemisiae Argyi, 150g Rhizoma Zingiberis Recens, 250g Oleum sesami and 1000g water are prepared from.
Ointment for treating burn and scald the most according to claim 1, it is characterised in that described ointment for treating burn and scald is by 120g Cortex Pini, 150g ice
Sheet, 150g Radix Angelicae Sinensis, 120g Radix Notoginseng, 150g Folium Artemisiae Argyi, 180g Rhizoma Zingiberis Recens, 220g Oleum sesami and 900g water are prepared from.
Ointment for treating burn and scald the most according to claim 1, it is characterised in that described ointment for treating burn and scald is by 180g Cortex Pini, 180g ice
Sheet, 120g Radix Angelicae Sinensis, 180g Radix Notoginseng, 180g Folium Artemisiae Argyi, 120g Rhizoma Zingiberis Recens, 280g Oleum sesami and 1000g water are prepared from.
5. the preparation method of the ointment for treating burn and scald described in a claim 1-4 any claim, it is characterised in that described method
Step is as follows:
One, Cortex Pini, Borneolum Syntheticum, Radix Angelicae Sinensis, Radix Notoginseng, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens clear water are cleaned, dry standby；
Two, add water to, in clean porcelain, be heated to 60～80 DEG C；
Three, Cortex Pini is put in porcelain, be heated to water boiling；
Four, Borneolum Syntheticum, Radix Angelicae Sinensis, Radix Notoginseng, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens are sequentially placed in porcelain and boil 10～20min, be then down to room temperature；
Five, filter, filtrate adds sesame oil stirring and becomes paste.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610895328.3A CN106267131A (en) | 2016-10-13 | 2016-10-13 | Ointment for treating burn and scald and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610895328.3A CN106267131A (en) | 2016-10-13 | 2016-10-13 | Ointment for treating burn and scald and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106267131A true CN106267131A (en) | 2017-01-04 |
Family
ID=57718450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610895328.3A Pending CN106267131A (en) | 2016-10-13 | 2016-10-13 | Ointment for treating burn and scald and preparation method thereof |
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| Country | Link |
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| CN (1) | CN106267131A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108686019A (en) * | 2018-07-30 | 2018-10-23 | 佛山科学技术学院 | A kind of Chinese medicine external ointment for treating scald and preparation method thereof |
| CN116785380A (en) * | 2021-12-15 | 2023-09-22 | 张曰忠 | Quick-acting Chinese herbal medicine spray for treating burns, scalds, wounds and cold |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101085075A (en) * | 2007-06-22 | 2007-12-12 | 韩连友 | Ointment for treating burn and scald and preparation method thereof |
| CN102836394A (en) * | 2011-06-21 | 2012-12-26 | 吴月安 | Burn and scald ointment composition and burn and scald ointment, and preparation method thereof |
| CN105708959A (en) * | 2015-07-28 | 2016-06-29 | 宋宽新 | Ointment for burns and scalds and preparation method of ointment |
-
2016
- 2016-10-13 CN CN201610895328.3A patent/CN106267131A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101085075A (en) * | 2007-06-22 | 2007-12-12 | 韩连友 | Ointment for treating burn and scald and preparation method thereof |
| CN102836394A (en) * | 2011-06-21 | 2012-12-26 | 吴月安 | Burn and scald ointment composition and burn and scald ointment, and preparation method thereof |
| CN105708959A (en) * | 2015-07-28 | 2016-06-29 | 宋宽新 | Ointment for burns and scalds and preparation method of ointment |
Non-Patent Citations (1)
| Title |
|---|
| 梁勇才: "《中国烧伤大全》", 30 June 1998, 学苑出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108686019A (en) * | 2018-07-30 | 2018-10-23 | 佛山科学技术学院 | A kind of Chinese medicine external ointment for treating scald and preparation method thereof |
| CN116785380A (en) * | 2021-12-15 | 2023-09-22 | 张曰忠 | Quick-acting Chinese herbal medicine spray for treating burns, scalds, wounds and cold |
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| C06 | Publication | ||
| PB01 | Publication | ||
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| RJ01 | Rejection of invention patent application after publication | ||
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Application publication date: 20170104 |