CN104666623A - Gastrointestinal drug and preparation method thereof - Google Patents
Gastrointestinal drug and preparation method thereof Download PDFInfo
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- CN104666623A CN104666623A CN201510092415.0A CN201510092415A CN104666623A CN 104666623 A CN104666623 A CN 104666623A CN 201510092415 A CN201510092415 A CN 201510092415A CN 104666623 A CN104666623 A CN 104666623A
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Abstract
The invention provides a gastrointestinal drug and a preparation method thereof. The gastrointestinal drug comprises 30-50 parts of defatted croton seed powder, 5-40 parts of Chinese thorowax roots, 30-90 parts of szechwan lovage rhizomes, 3-40 parts of Chinese eaglewood wood, 10-60 parts of cuttle bones, 5-50 parts of pilose asiabell roots, 5-50 parts of chicken's gizzard-membranes, 3-7 parts of dandelions, 5-20 parts of poria cocos and 5-15 parts of dried tangerine peels. Firstly, the pilose asiabell roots are stir-fried over low fire until the appearance turns yellow, a little rice vinegar with the mass accounting for 5%-10% of that of the Chinese thorowax roots is added to the Chinese thorowax roots and stir-fired to be dry, all the raw materials are mixed, 3 L of water is added, the mixture is heated to be boiling for 1-2 h and filtered, and a filtrate is cooled to the temperature of 40 DEG C and then can be taken. Traditional Chinese medicines adopted by the drug are free of toxic and side effects, the drug can be used for treating various gastrointestinal diseases such as acute and chronic gastritis, atrophic gastritis, gastric ulcers and duodenal ulcers, and the dependence of human bodies on western medicines is effectively avoided.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine for the treatment of gastrointestinal disease and preparation method thereof.
Background technology
Gastrointestinal disease is a kind of commonly encountered diseases frequently-occurring disease, and according to statistics, the sickness rate of gastrointestinal disease accounts for about 20% of population total number of persons.And sickness rate increases along with the increase at human body age, then more common for the middle-aged and elderly people of more than 50 years old, and male's sickness rate is same as women.Because gastrointestinal disease is a kind of commonly encountered diseases, the therefore ill rear majority of people paying no attention to, if but treat not in time, gastrointestinal disease can recurrent exerbation, and the later stage is very easily converted into cancer.Due to its recurrent exerbation, gastrointestinal disease is also regarded as one of difficult disease, once fall ill, then needs treatment in time and Long-term taking medicine, could be cured.But prolonged administration of drugs, especially Western medicine, secondary injury can be caused to the intestines and stomach of human body again, increase the burden of liver simultaneously, have side effects.
For the feature of gastrointestinal disease recurrent exerbation, Long-term taking medicine, treatment by Chinese herbs conditioning is the best way, first in Chinese medicine without the chemicals in Western medicine, avoid toxic and side effects, secondly, treatment by Chinese herbs has treatment and the dual function nursed one's health, gastric mucosa reparation in the process for the treatment of, eliminate the root of recurrent exerbation, human body can not produce dependency to Chinese medicine simultaneously, gets final product drug withdrawal after healing.But the formula, dosage etc. of Chinese medicine have again very large difference, in treatment gastropathy process, curative effect difference differs, and therefore, people need a kind of effective formula for the treatment of gastrointestinal disease.
Summary of the invention
An object of the present invention takes place frequently for solving current people's gastrointestinal disease, and long-term taking Western medicine causes the problem of secondary injury to human body, gastrointestinal drug providing a kind of pure Chinese medicine to make and preparation method thereof, this gastrointestinal drug can treat acute and chronic gastritis, the gastroenteropathys such as atrophic gastritis, gastric ulcer, duodenal ulcer, simultaneously without any side effects to human body.
A kind of gastrointestinal drug, comprises the raw material of following weight:
Semen Crotonis Pulveratum 30 ~ 50 parts; Radix Bupleuri 5 ~ 40 parts; Rhizoma Chuanxiong 30 ~ 90 parts; Lignum Aquilariae Resinatum 3 ~ 40 parts; Os Sepiae 10 ~ 60 parts; Radix Codonopsis 5 ~ 50 parts; Endothelium Corneum Gigeriae Galli 5 ~ 50 parts; Herba Taraxaci 3 ~ 7 parts; 5 ~ 20 parts, Poria; Pericarpium Citri Reticulatae 5 ~ 15 parts.
Further, a kind of gastrointestinal drug, comprises the raw material of following weight:
Semen Crotonis Pulveratum 35 ~ 45 parts; Radix Bupleuri 5 ~ 30 parts; Rhizoma Chuanxiong 30 ~ 60 parts; Lignum Aquilariae Resinatum 3 ~ 30 parts; Os Sepiae 10 ~ 50 parts; Radix Codonopsis 5 ~ 45 parts; Endothelium Corneum Gigeriae Galli 5 ~ 45 parts; Herba Taraxaci 3 ~ 6 parts; 5 ~ 15 parts, Poria; Pericarpium Citri Reticulatae 5 ~ 10 parts.
Further, a kind of gastrointestinal drug, comprises the raw material of following weight:
Semen Crotonis Pulveratum 35 ~ 40 parts; Radix Bupleuri 5 ~ 35 parts; Rhizoma Chuanxiong 30 ~ 50 parts; Lignum Aquilariae Resinatum 3 ~ 30 parts; Os Sepiae 10 ~ 50 parts; Radix Codonopsis 10 ~ 45 parts; Endothelium Corneum Gigeriae Galli 5 ~ 45 parts; Herba Taraxaci 3 ~ 6 parts; 5 ~ 15 parts, Poria; Pericarpium Citri Reticulatae 5 ~ 10 parts.
Further, a kind of gastrointestinal drug, comprises the raw material of following weight:
Semen Crotonis Pulveratum 30 ~ 35 parts; Radix Bupleuri 15 ~ 30 parts; Rhizoma Chuanxiong 30 ~ 50 parts; Lignum Aquilariae Resinatum 10 ~ 30 parts; Os Sepiae 10 ~ 40 parts; Radix Codonopsis 15 ~ 40 parts; Endothelium Corneum Gigeriae Galli 15 ~ 50 parts; Herba Taraxaci 4 ~ 6 parts; 10 ~ 20 parts, Poria; Pericarpium Citri Reticulatae 10 ~ 15 parts.
Present invention also offers a kind of preparation method of above-mentioned gastrointestinal drug, step is: first the parch of Radix Codonopsis low baking temperature become appearance to be yellow, a small amount of rice vinegar then fried dry will be placed in Radix Bupleuri, the quality of added rice vinegar is 5% ~ 10% of Radix Bupleuri quality, is mixed by all raw materials, puts into 3L water, be heated to boiling, boil 1 ~ 2 hour, filter, filtrate is cooled to 40 DEG C and can takes; Can spray in spray dryer by filtrate, routine operation makes spray drying powder, makes powder, or adds common medicine auxiliary agent, makes capsule or tablet simultaneously.
Beneficial effect of the present invention is: the Chinese medicine that the present invention adopts has no side effect, and can treat acute and chronic gastritis, atrophic gastritis, gastric ulcer, duodenal ulcer multiple the intestines and stomach class disease, effectively prevent the dependency of human body to Western medicine.
Detailed description of the invention
Hereafter will describe content of the present invention in conjunction with specific embodiments in detail.It should be noted that the combination of technical characteristic or the technical characteristic described in following embodiment should not be considered to isolated, they can mutually be combined thus be reached better technique effect.
Embodiment 1
In the present embodiment, the formula of gastrointestinal drug adopts following composition: Semen Crotonis Pulveratum 30 parts; Radix Bupleuri 5 parts; Rhizoma Chuanxiong 30 parts; Lignum Aquilariae Resinatum 3 parts; Os Sepiae 10 parts; Radix Codonopsis 5 parts; Endothelium Corneum Gigeriae Galli 5 parts; Herba Taraxaci 7 parts; 5 parts, Poria; Pericarpium Citri Reticulatae 15 parts.
Preparation method: first the parch of Radix Codonopsis low baking temperature become appearance to be yellow, will place a small amount of rice vinegar then fried dry in Radix Bupleuri, the quality of added rice vinegar is 5% of Radix Bupleuri quality, all raw materials are mixed, puts into 3L water, be heated to boiling, boil 1 ~ 2 hour, filter, filtrate is cooled to 40 DEG C.
Embodiment 2
In the present embodiment, the formula of gastrointestinal drug adopts following composition: Semen Crotonis Pulveratum 40 parts; Radix Bupleuri 40 parts; Rhizoma Chuanxiong 30 parts; Lignum Aquilariae Resinatum 40 parts; Os Sepiae 60 parts; Radix Codonopsis 50 parts; Endothelium Corneum Gigeriae Galli 50 parts; Herba Taraxaci 7 parts; 5 parts, Poria; Pericarpium Citri Reticulatae 5 parts.
Preparation method: first the parch of Radix Codonopsis low baking temperature become appearance to be yellow, will place a small amount of rice vinegar then fried dry in Radix Bupleuri, the quality of added rice vinegar is 6% of Radix Bupleuri quality, all raw materials are mixed, puts into 3L water, be heated to boiling, boil 1 ~ 2 hour, filter, filtrate is cooled to 40 DEG C.
Embodiment 3
In the present embodiment, the formula of gastrointestinal drug adopts following composition: Semen Crotonis Pulveratum 30 parts; Radix Bupleuri 40 parts; Rhizoma Chuanxiong 40 parts; Lignum Aquilariae Resinatum 20 parts; Os Sepiae 30 parts; Radix Codonopsis 40 parts; Endothelium Corneum Gigeriae Galli 20 parts; Herba Taraxaci 5 parts; 10 parts, Poria; Pericarpium Citri Reticulatae 10 parts.
Preparation method: first the parch of Radix Codonopsis low baking temperature become appearance to be yellow, will place a small amount of rice vinegar then fried dry in Radix Bupleuri, the quality of added rice vinegar is 7% of Radix Bupleuri quality, all raw materials are mixed, puts into 3L water, be heated to boiling, boil 1 ~ 2 hour, filter, filtrate is cooled to 40 DEG C.
Embodiment 4
In the present embodiment, the formula of gastrointestinal drug adopts following composition: Semen Crotonis Pulveratum 35 parts; Radix Bupleuri 20 parts; Rhizoma Chuanxiong 50 parts; Lignum Aquilariae Resinatum 15 parts; Os Sepiae 15 parts; Radix Codonopsis 25 parts; Endothelium Corneum Gigeriae Galli 15 parts; Herba Taraxaci 6 parts; 9 parts, Poria; Pericarpium Citri Reticulatae 8 parts.
Preparation method: first the parch of Radix Codonopsis low baking temperature become appearance to be yellow, will place a small amount of rice vinegar then fried dry in Radix Bupleuri, the quality of added rice vinegar is 8% of Radix Bupleuri quality, all raw materials are mixed, puts into 3L water, be heated to boiling, boil 1 ~ 2 hour, filter, filtrate is cooled to 40 DEG C.
Embodiment 5
In the present embodiment, the formula of gastrointestinal drug adopts following composition: Semen Crotonis Pulveratum 33 parts; Radix Bupleuri 18 parts; Rhizoma Chuanxiong 55 parts; Lignum Aquilariae Resinatum 35 parts; Os Sepiae 55 parts; Radix Codonopsis 35 parts; Endothelium Corneum Gigeriae Galli 35 parts; Herba Taraxaci 5 parts; 10 parts, Poria; Pericarpium Citri Reticulatae 10 parts.
Preparation method: first the parch of Radix Codonopsis low baking temperature become appearance to be yellow, will place a small amount of rice vinegar then fried dry in Radix Bupleuri, the quality of added rice vinegar is 9% of Radix Bupleuri quality, all raw materials are mixed, puts into 3L water, be heated to boiling, boil 1 ~ 2 hour, filter, filtrate is cooled to 40 DEG C.
Embodiment 6
In the present embodiment, the formula of gastrointestinal drug adopts following composition: Semen Crotonis Pulveratum 50 parts; Radix Bupleuri 40 parts; Rhizoma Chuanxiong 70 parts; Lignum Aquilariae Resinatum 30 parts; Os Sepiae 50 parts; Radix Codonopsis 38 parts; Endothelium Corneum Gigeriae Galli 45 parts; Herba Taraxaci 4 parts; 10 parts, Poria; Pericarpium Citri Reticulatae 10 parts.
Preparation method: first the parch of Radix Codonopsis low baking temperature become appearance to be yellow, will place a small amount of rice vinegar then fried dry in Radix Bupleuri, the quality of added rice vinegar is 7% of Radix Bupleuri quality, all raw materials are mixed, put into 3L water, be heated to boiling, boil 1 ~ 2 hour, filter, filtrate is cooled to 40 DEG C, and filtrate sprayed in spray dryer, routine operation makes spray drying powder, make powder, bath is taken.
Embodiment 7
In the present embodiment, the formula of gastrointestinal drug adopts following composition: Semen Crotonis Pulveratum 20 parts; Radix Bupleuri 20 parts; Rhizoma Chuanxiong 70 parts; Lignum Aquilariae Resinatum 10 parts; Os Sepiae 10 parts; Radix Codonopsis 5 parts; Endothelium Corneum Gigeriae Galli 5 parts; Herba Taraxaci 4 parts; 10 parts, Poria; Pericarpium Citri Reticulatae 10 parts.
Preparation method: first the parch of Radix Codonopsis low baking temperature become appearance to be yellow, will place a small amount of rice vinegar then fried dry in Radix Bupleuri, the quality of added rice vinegar is 10% of Radix Bupleuri quality, all raw materials are mixed, put into 3L water, be heated to boiling, boil 1 ~ 2 hour, filter, filtrate is cooled to 40 DEG C, and filtrate sprayed in spray dryer, routine operation makes spray drying powder, make powder, bath is taken.
Experimental result: the formula described in embodiment 1 to embodiment 7 is prepared into medicament by corresponding preparation method, then be respectively patient and take three weeks, pay a return visit after three weeks, therapeutic effect is divided into healing, effective and invalid three kinds, and the number of each classification is added up, statistical result is as shown in table 1 below:
Table 1: effective percentage statistical table after taking medicine three weeks
| Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | Embodiment 6 | Embodiment 7 | |
| To take medicine number | 87 | 93 | 105 | 77 | 69 | 58 | 93 |
| Cure | 78 | 62 | 70 | 41 | 50 | 31 | 61 |
| Effectively | 6 | 26 | 22 | 26 | 10 | 16 | 20 |
| Invalid | 3 | 5 | 13 | 10 | 9 | 11 | 12 |
| Effective percentage | 97％ | 95％ | 88％ | 87％ | 87％ | 81％ | 87％ |
By shown in table 1, we can find out, the pharmaceutical formulation effective percentage described in embodiment 1 to embodiment 7 all reaches more than 81%.
Although give some embodiments of the present invention, it will be understood by those of skill in the art that without departing from the spirit of the invention herein, can change embodiment herein.Above-described embodiment is exemplary, should using embodiment herein as the restriction of interest field of the present invention.
Claims (5)
1. a gastrointestinal drug, is characterized in that, comprises the raw material of following weight:
Semen Crotonis Pulveratum 30 ~ 50 parts; Radix Bupleuri 5 ~ 40 parts; Rhizoma Chuanxiong 30 ~ 90 parts; Lignum Aquilariae Resinatum 3 ~ 40 parts; Os Sepiae 10 ~ 60 parts; Radix Codonopsis 5 ~ 50 parts; Endothelium Corneum Gigeriae Galli 5 ~ 50 parts; Herba Taraxaci 3 ~ 7 parts; 5 ~ 20 parts, Poria; Pericarpium Citri Reticulatae 5 ~ 15 parts.
2. a gastrointestinal drug, is characterized in that, comprises the raw material of following weight:
Semen Crotonis Pulveratum 35 ~ 45 parts; Radix Bupleuri 5 ~ 30 parts; Rhizoma Chuanxiong 30 ~ 60 parts; Lignum Aquilariae Resinatum 3 ~ 30 parts; Os Sepiae 10 ~ 50 parts; Radix Codonopsis 5 ~ 45 parts; Endothelium Corneum Gigeriae Galli 5 ~ 45 parts; Herba Taraxaci 3 ~ 6 parts; 5 ~ 15 parts, Poria; Pericarpium Citri Reticulatae 5 ~ 10 parts.
3. a gastrointestinal drug, is characterized in that, comprises the raw material of following weight:
Semen Crotonis Pulveratum 35 ~ 40 parts; Radix Bupleuri 5 ~ 35 parts; Rhizoma Chuanxiong 30 ~ 50 parts; Lignum Aquilariae Resinatum 3 ~ 30 parts; Os Sepiae 10 ~ 50 parts; Radix Codonopsis 10 ~ 45 parts; Endothelium Corneum Gigeriae Galli 5 ~ 45 parts; Herba Taraxaci 3 ~ 6 parts; 5 ~ 15 parts, Poria; Pericarpium Citri Reticulatae 5 ~ 10 parts.
4. a gastrointestinal drug, is characterized in that, comprises the raw material of following weight:
Semen Crotonis Pulveratum 30 ~ 35 parts; Radix Bupleuri 15 ~ 30 parts; Rhizoma Chuanxiong 30 ~ 50 parts; Lignum Aquilariae Resinatum 10 ~ 30 parts; Os Sepiae 10 ~ 40 parts; Radix Codonopsis 15 ~ 40 parts; Endothelium Corneum Gigeriae Galli 15 ~ 50 parts; Herba Taraxaci 4 ~ 6 parts; 10 ~ 20 parts, Poria; Pericarpium Citri Reticulatae 10 ~ 15 parts.
5. as the preparation method of gastrointestinal drug as described in any one in Claims 1-4, it is characterized in that, first the parch of Radix Codonopsis low baking temperature become appearance to be yellow, will place a small amount of rice vinegar then fried dry in Radix Bupleuri, the quality of added rice vinegar is 5% ~ 10% of Radix Bupleuri quality, all raw materials are mixed, put into 3L water, be heated to boiling, boil 1 ~ 2 hour, filter, filtrate is cooled to 40 DEG C and can takes; Can spray in spray dryer by filtrate, routine operation makes spray drying powder, makes powder, or adds common medicine auxiliary agent, makes capsule or tablet simultaneously.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510092415.0A CN104666623A (en) | 2015-03-02 | 2015-03-02 | Gastrointestinal drug and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510092415.0A CN104666623A (en) | 2015-03-02 | 2015-03-02 | Gastrointestinal drug and preparation method thereof |
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| CN104666623A true CN104666623A (en) | 2015-06-03 |
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| CN201510092415.0A Pending CN104666623A (en) | 2015-03-02 | 2015-03-02 | Gastrointestinal drug and preparation method thereof |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1430999A (en) * | 2003-01-28 | 2003-07-23 | 南京师范大学 | Chinese herbal medicine combination for treating disease of disorder of bowels's function and its product |
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- 2015-03-02 CN CN201510092415.0A patent/CN104666623A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1430999A (en) * | 2003-01-28 | 2003-07-23 | 南京师范大学 | Chinese herbal medicine combination for treating disease of disorder of bowels's function and its product |
Non-Patent Citations (3)
| Title |
|---|
| 国家药典委员会: "《中华人民共和国药典 2010年版一部》", 31 January 2010, 中国医药科技出版社 * |
| 李廷国等: "自拟柴芍益胃汤治疗慢性胃炎36 例疗效观察", 《中国临床研究》 * |
| 马文军等: "健脾活血清热法治疗慢性萎缩性胃炎60 例", 《陕西中医学院学报》 * |
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Application publication date: 20150603 |