CN108434319B

CN108434319B - Traditional Chinese medicine composition for treating cheilitis and preparation method of medicine

Info

Publication number: CN108434319B
Application number: CN201810279481.2A
Authority: CN
Inventors: 贾颖
Original assignee: Shanxi University of Chinese Mediciine
Current assignee: Shanxi University of Chinese Mediciine
Priority date: 2018-03-30
Filing date: 2018-03-30
Publication date: 2021-07-30
Anticipated expiration: 2038-03-30
Also published as: CN108434319A

Abstract

The invention belongs to the field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine composition for treating cheilitis, which is prepared from the following substances in parts by weight: 24.5 to 35.4 portions of lithospermum, 12.2 to 18.8 portions of angelica, 9.6 to 16.7 portions of sanguisorba, 6.4 to 15.5 portions of raw liquorice, 8.3 to 17.6 portions of giant knotweed, 550 portions of olive oil, 4.5 to 9.7 portions of rhizoma anemarrhenae, 12.4 to 18.5 portions of mint, 6.6 to 12.7 portions of rhizoma atractylodis macrocephalae, 3.7 to 8.5 portions of schizonepeta, 7.5 to 11.2 portions of tree peony bark, 6.3 to 9.7 portions of divaricate saposhnikovia root, 2.4 to 8.1 portions of figwort, 1.5 to 4.8 portions of lily and 8.7 to 15.5 portions of pawpaw. The traditional Chinese medicine composition for treating cheilitis provided by the invention is exact in curative effect on cheilitis and small in toxic and side effects, and has the effects of relieving and moistening, preventing chapping, fading cheilogramma, supplementing water and preserving moisture.

Description

Traditional Chinese medicine composition for treating cheilitis and preparation method of medicine

Technical Field

The invention belongs to the technical field of traditional Chinese medicine medicaments, and particularly relates to a traditional Chinese medicine composition for treating cheilitis and a preparation method of the traditional Chinese medicine composition.

Background

The lip wind is the name of traditional Chinese medicine, also known as 'dry cracked lip', 'sinking lip', 'tight lip', 'thigh lip', 'swollen lip', 'sore lip focus', 'donkey mouth wind', 'donkey lip wind' and the like, and is mainly clinically characterized by swelling, itching and pain of lip, dryness, chapping, ulceration, running water, repeated desquamation, exudation and scabbing and the like, starts to descend to the lower lip when the disease starts, gradually expands to the upper lip and the lower lip, is not cured for a long time, and can last for years or longer. This disease is commonly seen in children and young women, and is equivalent to chronic cheilitis in modern medicine. Modern medicine considers that the cheilitis is a nonspecific inflammatory disease caused by mental, emotional, fatigue and other chronic diseases, mucosal epithelial parakeratosis or hyperkeratosis, exfoliative defect, normal arrangement of cells in the epithelium or edema, infiltration of lymphocytes in the lamina propria, plasma cells and the like, and vasodilation congestion. The etiology has not been clear to date and may be associated with certain chronic long-lasting stimuli. It is mostly seen in cold areas of the plateau or in dry seasons of the climate; bad habit of licking and biting lips; addiction to tobacco and wine, and scalding; playing a musical instrument; improper treatment after trauma is related to factors such as temperature, chemical and mechanical stimulation. With the influence of the functions of people in social life and work, the disease has high incidence rate and tends to increase year by year. Due to prolonged course of disease, the curative effect of western medicines clinically applied is often not obvious.

According to traditional Chinese medicine, lip wind is mainly caused by heat accumulated in the spleen and stomach and along with channels, smoked and burned lips, and consumes qi and damages yin after a long-term disease. The treatment mainly comprises clearing heat, eliminating dampness, nourishing yin, moistening dryness, dispelling pathogenic wind and relieving itching. In the treatment, attention should be paid to exterior-interior double relief, namely, relieving exterior pathogenic factors of muscles and skin, clearing damp-heat in spleen and stomach, so as to avoid that the pathogenic factors of fire-heat can not escape from the interior and are lingering and difficult to cure due to the fact that bitter and cold products are only thrown to purge fire and detoxify, and also to eliminate dampness without hurting yin and nourish yin without aiding dampness. The external treatment method can temporarily relieve the swelling, pain and itching of lips due to the action on local parts, and the components with the functions of clearing heat and removing toxicity are added into the external medicine, so that the effect of treating both principal and secondary aspects of disease is achieved to a certain extent. The Chinese medicinal herb oil prepared from the root of luohuang and the like is used for treating lip wind, and the main components of the Chinese medicinal herb oil comprise lithospermum, safflower, scutellaria baicalensis, angelica and the like, so that the effects of clearing heat, removing toxicity, relieving swelling, activating blood and relieving pain are achieved. The Chengui Sheng is treated by adopting the coptis ointment, the main components of the ointment are angelica, phellodendron, radix rehmanniae, turmeric and coptis, the auxiliary materials are sesame oil and yellow wax, and the sesame oil and the yellow wax are mixed with vitamin B2 powder into paste, and the ointment also has the effects of clearing away heat and toxic materials, and relieving swelling and pain. Referring to a large number of documents, some methods in ancient formulas of external application can be selected, such as external washing of a cheirapsis decoction (composed of 15 g of dittany bark, 10 g of common cnidium fruit, 10 g of shrubalthea bark, 30 g of broom cypress fruit and 30 g of lightyellow sophora root) or external application of a jade butterfly, and the effect can be achieved through clinical application. For lip wind, there are also Huanglian Gao (coptis root, dried rehmannia root, Chinese angelica, phellodendron bark, turmeric, ephedra herb and yellow wax) from Yi Zong jin Jian and Zi Gui you (gromwell root, Chinese angelica and sesame oil) from Wai Ke Zheng.

Modern inferior lip cosmetics are also an important factor in the development of lip wind. Therefore, when the patient is advised to forbid pungent foods, diet and emotion adjustment, the poor lip cosmetics are avoided to be used, and the bad habits of licking, biting and peeling lips and scales are abstained. The physician considers that the advantages of the traditional Chinese medicine are fully exerted, the source of the deficiency is explored, the whole treatment is paid attention to, and the effective prescription for treating the cheilitis is summarized, so that the clinical curative effect is improved.

Disclosure of Invention

Technical problem to be solved

Aiming at the existing technical problems, the invention provides the traditional Chinese medicine composition capable of treating the cheilitis and the preparation method of the traditional Chinese medicine composition.

(II) technical scheme

In order to achieve the purpose, the invention adopts the main technical scheme that:

a traditional Chinese medicine composition for treating cheilitis comprises the following substances in parts by weight:

24.5 to 35.4 portions of lithospermum, 12.2 to 18.8 portions of angelica, 9.6 to 16.7 portions of sanguisorba, 6.4 to 15.5 portions of raw liquorice, 8.3 to 17.6 portions of giant knotweed, 550 portions of olive oil, 4.5 to 9.7 portions of rhizoma anemarrhenae, 12.4 to 18.5 portions of mint, 6.6 to 12.7 portions of rhizoma atractylodis macrocephalae, 3.7 to 8.5 portions of schizonepeta, 7.5 to 11.2 portions of tree peony bark, 6.3 to 9.7 portions of divaricate saposhnikovia root, 2.4 to 8.1 portions of figwort, 1.5 to 4.8 portions of lily and 8.7 to 15.5 portions of pawpaw.

Preferably, the composition is prepared from the following materials in parts by weight:

27.4 to 33.4 of lithospermum, 14.5 to 17.2 of angelica, 11.6 to 15.5 of sanguisorba, 8.7 to 12.3 of raw liquorice, 12.7 to 15.4 of giant knotweed, 650 of olive oil 580, 6.2 to 7.7 of rhizoma anemarrhenae, 13.8 to 15.6 of mint, 7.2 to 8.9 of bighead atractylodes rhizome, 4.5 to 6.7 of fineleaf schizonepeta herb, 9.4 to 10.5 of tree peony bark, 7.3 to 8.6 of divaricate saposhnikovia root, 3.3 to 6.4 of figwort root, 2.7 to 4.2 of lily and 9.4 to 12.6 of pawpaw.

31.2 parts of lithospermum, 15.5 parts of angelica, 12.4 parts of sanguisorba, 11.6 parts of raw liquorice, 13.8 parts of giant knotweed, 600 parts of olive oil, 7.1 parts of rhizoma anemarrhenae, 14.5 parts of mint, 7.8 parts of bighead atractylodes rhizome, 5.4 parts of schizonepeta, 9.6 parts of moutan bark, 8.4 parts of divaricate saposhnikovia root, 4.7 parts of figwort root, 3.6 parts of lily and 10.3 parts of pawpaw.

Preferably, the composition also comprises the following substances in parts by weight:

3.2 to 6.8 portions of asparagus cochinchinensis, 14.2 to 19.6 portions of eclipta alba, 2.1 to 5.8 portions of clematis root and 7.4 to 10.6 portions of gentian.

Preferably, the dosage form of the traditional Chinese medicine composition comprises any one of paste, spray, ointment, liniment or tincture.

The medicament prepared from the traditional Chinese medicine composition in the technical scheme is applied to treating cheilitis.

The technical scheme also provides a preparation method of the traditional Chinese medicine composition for treating cheilitis, which comprises the following steps:

weighing the following medicinal materials in proportion: the preparation method comprises the following steps of weighing raw medicinal materials of lithospermum, angelica sinensis, garden burnet, raw liquorice, polygonum cuspidatum, olive oil, rhizoma anemarrhenae, mint, bighead atractylodes rhizome, schizonepeta, moutan bark, divaricate saposhnikovia root, figwort root, lily, pawpaw, cochinchnese asparagus root, eclipta alba, radix clematidis and felwort, respectively cleaning the weighed medicinal materials except the olive oil, removing impurities and draining for later use;

mixing and crushing the weighed lithospermum, angelica sinensis, garden burnet, raw liquorice, polygonum cuspidatum, rhizoma anemarrhenae, mint, bighead atractylodes rhizome, schizonepeta, moutan bark, divaricate saposhnikovia root, figwort root, lily, pawpaw, cochinchnese asparagus root, eclipta alba, clematis chinensis and gentian into particles with the size of 5-32 meshes to obtain mixed medicinal powder;

soaking the obtained mixed medicinal powder in the weighed olive oil for 3-5 days to obtain mixed medicinal oil;

heating the obtained mixed medicinal oil until the oil is boiled, continuously heating and decocting for 25-40 minutes, then standing to room temperature, removing the residue, and retaining the medicinal oil to obtain the medicinal oil of the traditional Chinese medicine composition for treating cheilitis.

Preferably, the medicinal oil is prepared into a clinically acceptable dosage form, including any one of paste, spray, ointment, liniment or tincture.

(III) advantageous effects

The invention has the beneficial effects that: the traditional Chinese medicine composition for treating cheilitis and the traditional Chinese medicine preparation prepared by the preparation method of the traditional Chinese medicine composition have the effects of relieving, moistening, preventing chapping, fading lip wrinkles, replenishing water and moisturizing; reasonable compatibility and strict medicine selection, and has definite curative effect and small toxic and side effects when being used for treating cheilitis.

In addition, the medicament prepared from the traditional Chinese medicine composition can be added with conventional auxiliary materials according to a conventional process to prepare clinically acceptable ointment, spray, ointment, liniment or tincture for people with lip swelling, hyperemia, rhagadia, rottenness and scab, and has the advantages of quick response, short treatment course, no relapse, no side effect and the like.

Detailed Description

For a better understanding of the present invention, its detailed description will be given by way of the following detailed description.

The invention is based on the 'Zigui oil' in the 'orthodox surgery' and combines the clinical practice to add traditional Chinese medicines and change the taste of sesame oil to form the current 'traditional Chinese medicine composition for treating lip wind'. It has effects in relieving dryness, moistening skin, preventing chapping, removing lip wrinkle, and supplementing water.

Example 1

Preparing the following medicinal materials by weight

24.5 parts of lithospermum, 12.2 parts of angelica, 9.6 parts of sanguisorba, 6.4 parts of raw liquorice, 8.3 parts of giant knotweed, 550 parts of olive oil, 4.5 parts of rhizoma anemarrhenae, 12.4 parts of mint, 6.6 parts of bighead atractylodes rhizome, 3.7 parts of schizonepeta, 7.5 parts of moutan bark, 6.3 parts of divaricate saposhnikovia root, 2.4 parts of figwort root, 1.5 parts of lily and 8.7 parts of pawpaw.

Weighing the following medicinal materials in proportion: the preparation method comprises the following steps of respectively cleaning the weighed medicinal materials except olive oil, removing impurities and draining for later use, wherein the medicinal materials comprise lithospermum, angelica sinensis, garden burnet, raw liquorice, polygonum cuspidatum, olive oil, rhizoma anemarrhenae, mint, bighead atractylodes rhizome, schizonepeta, moutan bark, divaricate saposhnikovia root, figwort root, lily and pawpaw;

mixing and crushing the weighed lithospermum, angelica, garden burnet, raw liquorice, polygonum cuspidatum, rhizoma anemarrhenae, mint, bighead atractylodes rhizome, schizonepeta, moutan bark, divaricate saposhnikovia root, figwort root, lily and pawpaw into particles with the size of 5 meshes to obtain mixed medicinal powder;

soaking the obtained mixed medicinal powder in the weighed olive oil for 3 days to obtain mixed medicinal oil;

heating the obtained mixed medicinal oil until the oil is boiled, continuously heating and decocting for 25 minutes, then standing to room temperature, removing the medicinal residue, and retaining the medicinal oil to obtain the medicinal oil of the traditional Chinese medicine composition for treating the cheilitis.

The medicinal oil of the medicament in the embodiment is prepared into clinically acceptable dosage forms, including any one of paste, spray, ointment, liniment or tincture.

Example 2

Preparing the following medicinal materials by weight

35.4 parts of lithospermum, 18.8 parts of angelica, 16.7 parts of sanguisorba, 15.5 parts of raw liquorice, 17.6 parts of giant knotweed, 720 parts of olive oil, 9.7 parts of rhizoma anemarrhenae, 18.5 parts of mint, 12.7 parts of bighead atractylodes rhizome, 8.5 parts of schizonepeta, 11.2 parts of moutan bark, 9.7 parts of divaricate saposhnikovia root, 8.1 parts of figwort root, 4.8 parts of lily and 15.5 parts of pawpaw.

mixing and crushing the weighed lithospermum, angelica, garden burnet, raw liquorice, polygonum cuspidatum, rhizoma anemarrhenae, mint, bighead atractylodes rhizome, schizonepeta, moutan bark, divaricate saposhnikovia root, figwort root, lily and pawpaw into 32-mesh particles to obtain mixed medicinal powder;

soaking the obtained mixed medicinal powder in the weighed olive oil for 5 days to obtain mixed medicinal oil;

heating the obtained mixed medicinal oil until the oil is boiled, continuously heating and decocting for 40 minutes, then standing to room temperature, removing the medicinal residue, and retaining the medicinal oil to obtain the medicinal oil of the traditional Chinese medicine composition for treating the cheilitis.

Example 3

Preparing the following medicinal materials by weight

Lithospermum 27.4, angelica sinensis 14.5, sanguisorba officinalis 11.6, raw liquorice 8.7, polygonum cuspidatum 12.7, olive oil 580, rhizoma anemarrhenae 6.2, mint 13.8, bighead atractylodes rhizome 7.2, schizonepeta 4.5, moutan bark 9.4, divaricate saposhnikovia root 7.3, figwort 3.3, lily 2.7 and pawpaw 9.4.

mixing and crushing the weighed lithospermum, angelica, garden burnet, raw liquorice, polygonum cuspidatum, rhizoma anemarrhenae, mint, bighead atractylodes rhizome, schizonepeta, moutan bark, divaricate saposhnikovia root, figwort root, lily and pawpaw into 8-mesh particles to obtain mixed medicinal powder;

soaking the obtained mixed medicinal powder in the weighed olive oil for 4 days to obtain mixed medicinal oil;

heating the obtained mixed medicinal oil until the oil is boiled, continuously heating and decocting for 30 minutes, then standing to room temperature, removing the medicinal residue, and retaining the medicinal oil to obtain the medicinal oil of the traditional Chinese medicine composition for treating the cheilitis.

Example 4

Preparing the following medicinal materials by weight

33.4 parts of lithospermum, 17.2 parts of angelica, 15.5 parts of sanguisorba, 12.3 parts of raw liquorice, 15.4 parts of giant knotweed, 650 parts of olive oil, 7.7 parts of rhizoma anemarrhenae, 15.6 parts of mint, 8.9 parts of bighead atractylodes rhizome, 6.7 parts of schizonepeta, 10.5 parts of moutan bark, 8.6 parts of divaricate saposhnikovia root, 6.4 parts of figwort root, 4.2 parts of lily and 12.6 parts of pawpaw.

mixing and crushing the weighed lithospermum, angelica, garden burnet, raw liquorice, polygonum cuspidatum, rhizoma anemarrhenae, mint, bighead atractylodes rhizome, schizonepeta, moutan bark, divaricate saposhnikovia root, figwort root, lily and pawpaw into particles with the size of 12 meshes to obtain mixed medicinal powder;

heating the obtained mixed medicinal oil until the oil is boiled, continuously heating and decocting for 35 minutes, then standing to room temperature, removing the medicinal residue, and retaining the medicinal oil to obtain the medicinal oil of the traditional Chinese medicine composition for treating the cheilitis.

Example 5

Preparing the following medicinal materials by weight

Example 6

Preparing the following medicinal materials by weight

24.5 parts of lithospermum, 12.2 parts of angelica, 9.6 parts of sanguisorba, 6.4 parts of raw liquorice, 8.3 parts of giant knotweed, 550 parts of olive oil, 4.5 parts of rhizoma anemarrhenae, 12.4 parts of mint, 6.6 parts of bighead atractylodes rhizome, 3.7 parts of schizonepeta, 7.5 parts of moutan bark, 6.3 parts of divaricate saposhnikovia root, 2.4 parts of figwort root, 1.5 parts of lily, 8.7 parts of pawpaw, 3.2 parts of asparagus, 14.2 parts of eclipta alba, 2.1 parts of radix clematidis and 7.4 parts of gentian.

mixing and crushing the weighed lithospermum, angelica sinensis, garden burnet, raw liquorice, polygonum cuspidatum, rhizoma anemarrhenae, mint, bighead atractylodes rhizome, schizonepeta, moutan bark, divaricate saposhnikovia root, figwort root, lily, pawpaw, cochinchnese asparagus root, eclipta alba, clematis chinensis and gentian into 16-mesh particles to obtain mixed medicinal powder;

Example 7

Preparing the following medicinal materials by weight

35.4 parts of lithospermum, 18.8 parts of angelica, 16.7 parts of sanguisorba, 15.5 parts of raw liquorice, 17.6 parts of giant knotweed, 720 parts of olive oil, 9.7 parts of rhizoma anemarrhenae, 18.5 parts of mint, 12.7 parts of bighead atractylodes rhizome, 8.5 parts of schizonepeta, 11.2 parts of moutan bark, 9.7 parts of divaricate saposhnikovia root, 8.1 parts of figwort root, 4.8 parts of lily, 15.5 parts of pawpaw, 6.8 parts of asparagus, 19.6 parts of eclipta alba, 5.8 parts of radix clematidis and 10.6 parts of gentian.

mixing and crushing the weighed lithospermum, angelica sinensis, garden burnet, raw liquorice, polygonum cuspidatum, rhizoma anemarrhenae, mint, bighead atractylodes rhizome, schizonepeta, moutan bark, divaricate saposhnikovia root, figwort root, lily, pawpaw, cochinchnese asparagus root, eclipta alba, clematis chinensis and gentian into 32-mesh particles to obtain mixed medicinal powder;

Example 8

Preparing the following medicinal materials by weight

Lithospermum 27.4, angelica sinensis 14.5, sanguisorba officinalis 11.6, raw liquorice 8.7, polygonum cuspidatum 12.7, olive oil 580, rhizoma anemarrhenae 6.2, mint 13.8, bighead atractylodes rhizome 7.2, schizonepeta 4.5, moutan bark 9.4, divaricate saposhnikovia root 7.3, radix scrophulariae 3.3, lily 2.7, pawpaw 9.4, radix asparagi 3.2, eclipta alba 14.2, radix clematidis 2.1 and gentian 7.4.

mixing and crushing the weighed lithospermum, angelica sinensis, garden burnet, raw liquorice, polygonum cuspidatum, rhizoma anemarrhenae, mint, bighead atractylodes rhizome, schizonepeta, moutan bark, divaricate saposhnikovia root, figwort root, lily, pawpaw, cochinchnese asparagus root, eclipta alba, clematis chinensis and gentian into 12-mesh particles to obtain mixed medicinal powder;

Example 9

Preparing the following medicinal materials by weight

33.4 parts of lithospermum, 17.2 parts of angelica, 15.5 parts of sanguisorba, 12.3 parts of raw liquorice, 15.4 parts of giant knotweed, 650 parts of olive oil, 7.7 parts of rhizoma anemarrhenae, 15.6 parts of mint, 8.9 parts of bighead atractylodes rhizome, 6.7 parts of herba schizonepetae, 10.5 parts of moutan bark, 8.6 parts of divaricate saposhnikovia root, 6.4 parts of radix scrophulariae, 4.2 parts of lily, 12.6 parts of pawpaw, 6.8 parts of radix asparagi, 19.6 parts of eclipta alba, 5.8 parts of radix clematidis and 10.6 parts of gentian.

mixing and crushing the weighed lithospermum, angelica sinensis, garden burnet, raw liquorice, polygonum cuspidatum, rhizoma anemarrhenae, mint, bighead atractylodes rhizome, schizonepeta, moutan bark, divaricate saposhnikovia root, figwort root, lily, pawpaw, cochinchnese asparagus root, eclipta alba, clematis chinensis and gentian into 8-mesh particles to obtain mixed medicinal powder;

Scope of application

(1) Direction of application

The composition and the medicament thereof are added with conventional auxiliary materials according to the conventional process to prepare clinically acceptable emplastrum, spray, ointment, liniment or tincture.

The medicinal oil is filled into a brown sealed bottle, and when in use, a cotton swab is used for dipping a proper amount of medicinal liquid and directly and uniformly applying the medicinal liquid on lips. It can be applied for 3 times (or applied at any time) 1 day.

(2) Mainly treats cheilitis

Matters of attention

(1) It is contraindicated for allergy to this product.

(2) The product can be used for patients with anaphylaxis, pustule ulceration, and infection.

Clinical trial cases

Case 1

Suzhong, female, 6 years old.

Initial diagnosis in 2016, 2, 23 months.

The main complaints are: lips were repeatedly peeled, chapped for 3 years, and aggravated for 10 days.

The current medical history: the patients complain about dry lips after the cold and fever before 10 days, often lick the lips with the tongue, the symptoms are not obviously improved but gradually worsened, the normal food is preferred, the food intake is poor, the stool is dry, and the patient can walk in 2 days. Red and red lips and a circle around the lips, dryness, partial skin cracking, pain, convenient urination, 2-day stool, pale tongue and white greasy tongue coating.

And (3) Western diagnosis: exfoliative cheilitis.

Traditional Chinese medicine diagnosis: cheilopathy (phlegm-heat accumulation in the interior).

The medicinal oil prepared from the traditional Chinese medicine composition in the embodiment 1 developed by the applicant is tried 3 times a day.

Twice diagnosis in 2016, 3 months and 1 day: the red swelling and dryness around the lips basically subsides, the appetite is slightly better than before, and the stool is smooth.

The medicinal oil is used for 1 week.

No recurrence occurred after 1 month follow-up.

Case 2

Wu-Chi, women, 16 years old.

Initial diagnosis in 2016, 6 months and 25 days.

The main complaints are: the lips are red, swollen, dry and cracked, with skin peeling for two months, and the weight is increased for 1 week.

The current medical history: the patient has red, swollen and chapped lips with peeling, the lips are slightly relieved after being coated with the lipstick, and the lips are aggravated again after being eaten with spicy food one week before. The symptoms are red, swollen and chapped lips, desquamation with pain, normal urination and dry stool.

The ointment prepared from the traditional Chinese medicine composition developed by the applicant in the embodiment 2 is tried, and the ointment is dipped by a cotton swab and is externally applied to the affected part 3 times a day.

Two diagnoses in 2016, 7 months and 2 days: the red and swollen lips are relieved, the pain and the dry and cracked symptoms are obviously improved, the desquamation disappears, and the lips can be accommodated and sleep conveniently.

The ointment is applied for 1 week.

No recurrence occurred after 1 month follow-up.

Case 3

Lie, woman, 32 years old.

Initial diagnosis in 2017, 2 and 11 months.

The main complaints are: chap of the lips with a skin peeling of one week.

The current medical history: after the patients are cured and improved for the cold and fever two weeks, the lips of the patients are cracked and peeled, the patients have pharyngalgia occasionally, sleep, the tongue is red, the coating is white, the teeth are marked at the edges, and the pulse is fine and smooth.

The ointment prepared from the traditional Chinese medicine composition developed by the applicant in the embodiment 3 is tried, and the ointment is dipped by a cotton swab and applied to the affected part 3 times a day.

Twice diagnosis in 2 months and 18 days in 2017: after the medicine is taken, the chap of the mouth and the lip and the desquamation basically subside.

The ointment is applied for 1 week.

No recurrence occurred after 1 month follow-up.

Case 4

Teacher certain, woman, 7 years old.

Initial diagnosis in 2017, 2 and 11 months.

The main complaints are: the lips are dry and cracked and peeled for two weeks.

The current medical history: the patient has dry and cracked lips and desquamation after high fever two weeks before, and the patient has complaints of hypodynamia, poor appetite, good sleep, convenient adjustment, red tongue, white fur and thready and rapid pulse.

The ointment prepared from the traditional Chinese medicine composition developed by the applicant in the embodiment 4 is tried, and the ointment is dipped by a cotton swab and applied to the affected part for 3 times a day.

Twice diagnosis in 12 days in 4 months in 2017: after the medicine is taken, the dry and cracked lips and the desquamation basically subside.

The ointment is applied for 1 week.

After 1 month, no complaints were observed in the follow-up.

Case 5

Chen is certain, 13 years old.

Initial diagnosis in 2017, 2 and 11 months.

The main complaints are: the lips are red, swollen, dry and cracked repeatedly and have a skin peeling time of more than 3 months.

The current medical history: the red, swollen, dry and cracked lips and skin of a patient are relieved by self-applying lipstick externally, and the lipstick can be repeatedly applied, so that the patient can take the lipstick conveniently, sleep conveniently, have red tongue with white coating and tooth marks at the edge, and have a thready and smooth pulse.

The ointment prepared from the traditional Chinese medicine composition developed by the applicant in the embodiment 5 is tried, and the ointment is dipped by a cotton swab and is externally applied to the affected part 3 times a day.

Twice diagnosis in 3 months and 4 days in 2017: the red and swollen lips are relieved, the symptom of chapping is obviously improved, the desquamation disappears, and the lips can be accommodated and sleep conveniently.

The paste is applied for 1 week.

No recurrence occurred after 1 month follow-up.

Case 6

Zhangqi, female, 8 years old.

Initial diagnosis in 2017, 2 months and 25 days.

The main complaints are: red and swollen lips and lips, and drying for 2 weeks.

The current medical history: the lips and the perilabial redness and swelling of the patient, dryness and desquamation, lip licking habit, no discomfort, pale red tongue with tooth marks, white fur and slippery pulse.

The medicinal oil prepared from the traditional Chinese medicine composition in the embodiment 6 developed by the applicant is tried, and the medicinal oil is dipped by a cotton swab and is externally applied to the affected part for 3 times a day.

After taking the medicine, the red swelling subsides, and the dryness and the desquamation are obviously relieved after the medicine is taken for two diagnoses in 3 months and 4 days.

The medicinal oil is used for 1 week.

No recurrence occurred after 1 month follow-up.

Case 7

Sunzhi, female, age 21. Initial diagnosis in 2017, 2 and 11 months.

The main complaints are: the lips are dry and chapped for more than 2 weeks.

The current medical history: dry, chapped and crusted lips, pain and itching, regular menstruation, smooth and regular sleep, dry mouth, convenient adjustment, pale red tongue with thin and yellow coating, and thready and rapid pulse.

The ointment prepared from the traditional Chinese medicine composition in the embodiment 7 developed by the applicant is tried, and the ointment is dipped by a cotton swab and is externally applied to the affected part 3 times a day.

And 2, twice diagnosis in 18 days: chap around the lips is reduced, and itching is relieved. Regulating sleep, regulating the condition with ease, a pale red tongue with thin and yellow coating and a thready and rapid pulse.

The ointment is applied for 1 week.

No recurrence occurred after 1 month follow-up.

Case 8

Bai Zhi, male, 13 years old.

Initial diagnosis in 2017, 4 months and 7 days.

The main complaints are: the lips are dry and desquamated for more than 10 days.

The current medical history: the patient complains of desquamation, dryness, easy accommodation and sleep, pale red tongue with thin and white coating and thready and rapid pulse.

The ointment prepared from the traditional Chinese medicine composition developed by the applicant in the embodiment 8 is tried, and the ointment is dipped by a cotton swab and is externally applied to the affected part 3 times a day.

And 4, twice diagnosis in 4 months and 14 days: after the medicine is taken, the desquamation and the dryness basically disappear.

And then applying the ointment for 1 week.

No recurrence occurred after 1 month follow-up.

Case 9

Wangzhi, female, 19 years old.

Initial diagnosis in 12 months and 9 days in 2017.

The main complaints are: the lips are repeatedly dried and chapped for more than 1 month.

The current medical history: patients complain of dry and chapped lips, the lipstick applied externally by oneself has no relief, poor appetite, good sleep, convenient adjustment, pale red tongue, thin and white coating and thready and weak pulse.

The ointment prepared from the traditional Chinese medicine composition developed by the applicant in the embodiment 9 is tried, and the ointment is dipped by a cotton swab and is externally applied to the affected part 3 times a day.

And (2) carrying out secondary diagnosis 12 months and 16 days: after the medicine is taken, the chap is reduced, the dryness disappears, and the medicine can be taken and put to sleep conveniently. And then applying the ointment for 1 week.

No recurrence occurred after 1 month follow-up.

The above description is only a preferred embodiment of the present invention, and is not intended to limit the structure of the present invention in any way, and all simple modifications, equivalent variations and modifications made to the above embodiments according to the technical spirit of the present invention are within the scope of the technical solution of the present invention.

Claims

1. A traditional Chinese medicine composition for treating cheilitis is characterized by being prepared from the following substances in parts by weight:

2. The traditional Chinese medicine composition of claim 1, which is prepared from the following substances in parts by weight:

3. The traditional Chinese medicine composition as claimed in claim 2, which is prepared from the following materials in parts by weight:

31.2 parts of lithospermum, 15.5 parts of angelica, 12.4 parts of sanguisorba, 11.6 parts of raw liquorice, 13.8 parts of giant knotweed, 600 parts of olive oil, 7.1 parts of rhizoma anemarrhenae, 14.5 parts of mint, 7.8 parts of bighead atractylodes rhizome, 5.4 parts of schizonepeta, 9.6 parts of moutan bark, 8.4 parts of divaricate saposhnikovia root, 4.7 parts of figwort root, 3.6 parts of lily and 10.3 parts.

4. The traditional Chinese medicine composition of any one of claims 1 to 3, wherein the dosage form of the traditional Chinese medicine composition comprises any one of paste, spray, liniment or tincture.

5. A traditional Chinese medicine composition for treating cheilitis is characterized by being prepared from the following substances in parts by weight:

24.5 to 35.4 portions of lithospermum, 12.2 to 18.8 portions of angelica, 9.6 to 16.7 portions of sanguisorba, 6.4 to 15.5 portions of raw liquorice, 8.3 to 17.6 portions of giant knotweed, 550 portions of olive oil, 4.5 to 9.7 portions of rhizoma anemarrhenae, 12.4 to 18.5 portions of mint, 6.6 to 12.7 portions of rhizoma atractylodis macrocephalae, 3.7 to 8.5 portions of schizonepeta, 7.5 to 11.2 portions of tree peony bark, 6.3 to 9.7 portions of divaricate saposhnikovia root, 2.4 to 8.1 portions of figwort, 1.5 to 4.8 portions of lily, 8.7 to 15.5 portions of pawpaw, 3.2 to 6.8 portions of radix asparagi, 14.2 to 19.6 portions of eclipta, 2.1 to 5.8 portions of radix clematidis and 7.4 to 10.6 portions of gentian;

alternatively, the first and second electrodes may be,

27.4 to 33.4 of lithospermum, 14.5 to 17.2 of angelica, 11.6 to 15.5 of sanguisorba, 8.7 to 12.3 of raw liquorice, 12.7 to 15.4 of giant knotweed, 580-650 of olive oil, 6.2 to 7.7 of rhizoma anemarrhenae, 13.8 to 15.6 of mint, 7.2 to 8.9 of bighead atractylodes rhizome, 4.5 to 6.7 of fineleaf schizonepeta herb, 9.4 to 10.5 of tree peony bark, 7.3 to 8.6 of divaricate saposhnikovia root, 3.3 to 6.4 of figwort, 2.7 to 4.2 of lily, 9.4 to 12.6 of pawpaw, 3.2 to 6.8 of cochinchnese asparagus root, 14.2 to 19.6 of eclipta alba, 2.1 to 5.8 of clematis root and 7.4 to 10.6 of gentian.

6. The traditional Chinese medicine composition of claim 5, wherein the dosage form of the traditional Chinese medicine composition comprises any one of paste, spray, liniment or tincture.

7. The preparation method of the traditional Chinese medicine composition for treating cheilitis as claimed in any one of claims 1 to 3, which comprises the following steps:

mixing and crushing the weighed lithospermum, angelica, garden burnet, raw liquorice, polygonum cuspidatum, rhizoma anemarrhenae, mint, bighead atractylodes rhizome, schizonepeta, moutan bark, divaricate saposhnikovia root, figwort root, lily and pawpaw into particles of 5-32 meshes to obtain mixed medicinal powder;

8. The preparation method of the Chinese medicinal composition for treating cheilitis as claimed in claim 5, comprising the following steps:

9. The method of any one of claims 7 or 8, wherein the medicinal oil is formulated into a clinically acceptable dosage form, including any one of a paste, a spray, a liniment or a tincture.