CN104435835A - Traditional Chinese medicine lotion used for treating pediatric hand-foot-and-mouth disease - Google Patents

Traditional Chinese medicine lotion used for treating pediatric hand-foot-and-mouth disease Download PDF

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CN104435835A
CN104435835A CN201410701879.2A CN201410701879A CN104435835A CN 104435835 A CN104435835 A CN 104435835A CN 201410701879 A CN201410701879 A CN 201410701879A CN 104435835 A CN104435835 A CN 104435835A
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chinese medicine
traditional chinese
foot
mouth disease
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CN104435835B (en
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胡开明
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • A61K36/855Clerodendrum, e.g. glorybower
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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Abstract

The invention discloses traditional Chinese medicine lotion used for treating a pediatric hand-foot-and-mouth disease, and relates to the technical field of traditional Chinese medicine combination. The traditional Chinese medicine lotion comprises the following components: 25-30 parts of indigowoad leaves, 25-30 parts of morus alba leaves, 25-30 parts of lophatherum graciles, 25-30 parts of lonicera japonica, 25-30 parts of sweet wormwood herbs, 25-30 parts of rhizoma phragmitis and 25-30 parts of divaricate saposhnikovia roots. Compared with existing western medicines used for treating the pediatric hand-foot-and-mouth disease, the traditional Chinese medicine lotion is used for treating the pediatric hand-foot-and-mouth disease, the course of treatment is short, a child does not have fever symptoms after taking the traditional Chinese medicine lotion for three days, herpes of hands, feet and the mouth of the child are all eliminated, a curative criterion is reached, the effective rate reaches 97%, and the recovery rate reaches more than 90%.

Description

Be used for the treatment of the external washout with traditional Chinese herbs agent of Hand-Food-Mouth Disease
Technical field
The present invention relates to technical field of traditional Chinese medicine, especially a kind of Chinese medicine lotion being used for the treatment of Hand-Food-Mouth Disease.
Background technology
Hand-foot-mouth disease is that a kind of child's common transmittable having various human enterovirus to cause is sick, and be the Class C infectious disease of China's statutory report management, its clinical manifestation is general 3-7 days incubation period, does not have obvious prodrome: the unexpected onset of most patient.Main infringement hands, foot, mouth, buttocks four positions; More there are the four not features of bitterly, not itching, not forming a scab, not scabbing clinically.Initial stage can have slightly feels symptom.Most patients symptom is slight, with generate heat and the erythra at the position such as hands, foot, oral cavity or herpes for cardinal symptom, due to canker sore pain, the refusing to eat of infant sialorrhea; Can be there are aseptic meningitis, encephalitis, AFP Cases, neurogenic pulmonary edema and myocarditis etc. in small number of patients, indivedual children with serious disease disease progression is fast, can cause death.This is sick popular in obvious provincialism, and the whole year all can occur, and the general 5-7 month is onset peak.Group contagion is there is in primary disease Chang Yi in mechanism of nursery schools and childcare centres.Crosss infection in hospital etc. also can cause propagation.This disease transmission is strong, and route of transmission is complicated, and epidemic strength is large, propagates fast, can cause at short notice and be very popular.Enterovirus infectiousness is strong, inapparent infection ratio large propagation approach is complicated, spread speed is fast, controls difficulty large, easily occurs in outburst and short time popular in a big way.Costly, healing time is 7-10 days to conventional western medicine antiviral therapy, and the course for the treatment of is long, and all carries out intravenous administration increase children's misery.
Summary of the invention
The invention provides a kind of Chinese medicine lotion being used for the treatment of Hand-Food-Mouth Disease, it can solve, and the medical expense of doctor trained in Western medicine to Hand-Food-Mouth Disease be high, problem that the course for the treatment of is long.
In order to solve the problems of the technologies described above, the technical solution adopted in the present invention is:
Its composition is made up of the raw material of following weight portion:
Folium Isatidis 25 parts-30 parts; 25 parts-30 parts, Folium Mori; Herba Lophatheri 25 parts-30 parts; Flos Lonicerae 25 parts-30 parts; Herba Artemisiae Annuae 25 parts-30 parts; Rhizoma Phragmitis 25 parts-30 parts; Radix Saposhnikoviae 25 parts-30 parts.
In technique scheme, scheme can also be more specifically: its composition is made up of the raw material of following weight portion: Folium Isatidis 30 parts; 30 parts, Folium Mori; Herba Lophatheri 30 parts; Flos Lonicerae 30 parts; Herba Artemisiae Annuae 30 parts; Rhizoma Phragmitis 30 parts; Radix Saposhnikoviae 30 parts.
Further: its composition is made up of the raw material of following weight portion: Folium Isatidis 25 parts; 25 parts, Folium Mori; Herba Lophatheri 25 parts; Flos Lonicerae 25 parts; Herba Artemisiae Annuae 25 parts; Rhizoma Phragmitis 25 parts; Radix Saposhnikoviae 25 parts.
Folium Isatidis of the present invention, is Folium Isatidis again, is leaf or the branch and leaf of Verbenaceae Herba Diclipterae Chinensis, few section plant polygonum tinctorium ait., cruciferae isatis, careless Folium Isatidis or acanthaceous vegetable acanthaceous indigo etc.Folium Isatidis is mainly used in pyretic toxicity and sends out the diseases such as speckle, erysipelas, laryngopharynx swelling and pain, aphtha of the mouth and tongue, sore and toxic.
Folium Mori of the present invention are dried leaves of moraceae plants Mulberry, have another name called a Mulberry, Jing Sang, Fructus Mori tree, yellow wood etc., have the effects such as blood pressure lowering, blood fat, antiinflammatory.
Herba Lophatheri of the present invention, be the dry stem and leaf of grass family herbaceos perennial Herba Lophatheri, effect of Herba Lophatheri is clearing away heat-fire, relieving restlessness, inducing diuresis for treating stranguria syndrome, and the effect of Herba Lophatheri controls disease heat in the heart, pyretic toxicity wind.
Flos Lonicerae of the present invention, has another name called Radix Ophiopogonis, Flos Lonicerae, Flos Lonicerae etc., is described as the good medicine of heat-clearing and toxic substances removing from ancient times.Its property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil.Flos Lonicerae can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile disease, as fever of the body, dermexanthesis, sends out the cards such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, equal Be very effective.
Herba Artemisiae Annuae of the present invention is the dry aerial parts of feverfew Herba Artemisiae annuae.Sweet in the mouth is micro-pungent, and gas is trembled with fear, nontoxic.For the laryngopharynx swelling and pain that interior-heat causes, conjunctival congestion, the diseases such as dry mouth and tougue.
Rhizoma Phragmitis of the present invention is the fresh or dry rhizome of monocotyledon grass family phragmites communis.There is clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, effect of diuresis.Cure mainly: for calentura excessive thirst, gastropyretic vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.
Radix Saposhnikoviae of the present invention is the root of Umbelliferae herbaceos perennial Radix Saposhnikoviae.Radix Saposhnikoviae has another name called that copper rues, Rhizoma Cibotii, Radix Saposhnikoviae acrid in the mouth, sweet, slightly warm in nature; Return lung, spleen, liver, urinary bladder channel; Gas perfume rises loose; There is expelling pathogenic wind from the body surface, removing damp and stopping pain, soothing the liver spasmolytic, effect of killing parasites for relieving itching; Cure mainly affection of exogenous wind-cold, headache stiffness of the nape, dizzy dusk is puckery, anemofrigid-damp arthralgia, and joint is ached, and stomachache is had loose bowels, discharging fresh blood stool, broken damaging the spleen and stomach wind, and measles is thoroughly difficult, rubella pruritus, skin infection from the beginning of.
Owing to have employed technique scheme, the present invention compared with prior art, has following beneficial effect:
Owing to adopting Chinese medicine lotion of the present invention to treat Hand-Food-Mouth Disease, treat short, medication three days, children's is without heating paresthesia, and hands, foot, herpes of mouth all disappear, and reach criterion of cure, and effective percentage reaches 97%, and cure rate reaches more than 90%.
Specific embodiment
Below in conjunction with specific embodiment, the invention will be further described, but technical scope of the present invention does not limit by these embodiments.All proportional quantities are calculated all by weight percentage below.
Embodiment 1:
The preparation method of this Chinese medicine lotion is for adopting Folium Isatidis 30 grams, 30 grams, Folium Mori, Herba Lophatheri 30 grams, Flos Lonicerae 30 grams, Herba Artemisiae Annuae 30 grams, Rhizoma Phragmitis 30 grams and Radix Saposhnikoviae 30 grams as raw material, pour these 7 kinds of herbal raw materials into marmite, add the soak by water of 5000 milliliters, after water boils, little fire decocts 30 minutes and get final product.
clinical trial part:
1, test case totally 86 examples, the age is 0.5 years old-10 years old;
2, Hand-Food-Mouth Disease mild diagnostic criteria:
1., Acute onset, heating, oral mucosa occurs being dispersed in herpes, and maculopapule, herpes appear in hands, foot and buttocks, have blush around herpes, and in bleb, liquid is less.
2., with symptoms such as cough, watery nasal discharge, inappetence.Some cases only shows as erythra or herpangina.
3., red tongue, white and greasy fur or yellow greasy, floating superficial venule of the index finger purple or the floating number of pulse condition.
3, Therapeutic Method:
Use the lotion that embodiment 1 is obtained, carry out fumigation and wash method to 86 routine patients, method is: the dose of embodiment 1 is the consumption of one pair of medicine, and usage is total amount Third Mate, every day one pair, fumigation and wash method 20 minutes after decocting, twice daily; Continuous fumigation and wash method three days;
In these three days, the use of Chinese medicine gargle can be coordinated, total amount Third Mate, every day one pair, point four rinsing the mouth, continuous rinsing the mouth three days.
Each pair of Chinese medicine gargle is made up of Radix Scutellariae 5 grams, SHANZHIZI 5 grams, Herba Taraxaci 5 grams, Fructus Forsythiae 5 grams, Indigo Naturalis powder 2 grams of raw materials, during preparation, pour Radix Scutellariae, SHANZHIZI, Herba Taraxaci and Fructus Forsythiae into marmite, add 200 ml waters to decoct, after water boils, little fire decocts 30 minutes, Guan Huo, leaches medicinal liquid, adds Indigo Naturalis powder and mixes well.
4, therapeutic effect:
Children's is without heating paresthesia, and hands, foot, herpes of mouth all disappear, and reach criterion of cure, and effective percentage reaches 97%, and cure rate reaches more than 90%.

Claims (3)

1. be used for the treatment of a Chinese medicine lotion for Hand-Food-Mouth Disease, it is characterized in that its composition is made up of the raw material of following weight portion:
Folium Isatidis 25 parts-30 parts; 25 parts-30 parts, Folium Mori; Herba Lophatheri 25 parts-30 parts; Flos Lonicerae 25 parts-30 parts; Herba Artemisiae Annuae 25 parts-30 parts; Rhizoma Phragmitis 25 parts-30 parts; Radix Saposhnikoviae 25 parts-30 parts.
2. the Chinese medicine lotion being used for the treatment of Hand-Food-Mouth Disease according to claim 1, is characterized in that its composition is made up of the raw material of following weight portion:
Folium Isatidis 30 parts; 30 parts, Folium Mori; Herba Lophatheri 30 parts; Flos Lonicerae 30 parts; Herba Artemisiae Annuae 30 parts; Rhizoma Phragmitis 30 parts; Radix Saposhnikoviae 30 parts.
3. the Chinese medicine lotion being used for the treatment of Hand-Food-Mouth Disease according to claim 1, is characterized in that its composition is made up of the raw material of following weight portion:
Folium Isatidis 25 parts; 25 parts, Folium Mori; Herba Lophatheri 25 parts; Flos Lonicerae 25 parts; Herba Artemisiae Annuae 25 parts; Rhizoma Phragmitis 25 parts; Radix Saposhnikoviae 25 parts.
CN201410701879.2A 2014-11-28 2014-11-28 For treating the external washout with traditional Chinese herbs agent of Hand-Food-Mouth Disease Active CN104435835B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105031412A (en) * 2015-09-15 2015-11-11 南京医科大学第一附属医院 Cleaning fluid for treating hand-foot-and-mouth disease of infants and preparing method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张国梁 等: "手足口病中医治疗经验及预防方药研究概况", 《中医药临床杂志》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105031412A (en) * 2015-09-15 2015-11-11 南京医科大学第一附属医院 Cleaning fluid for treating hand-foot-and-mouth disease of infants and preparing method thereof

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