CN104649937B - 苯磺酰肼类gpr119激动剂、制备方法及其用途 - Google Patents
苯磺酰肼类gpr119激动剂、制备方法及其用途 Download PDFInfo
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- CN104649937B CN104649937B CN201510080270.2A CN201510080270A CN104649937B CN 104649937 B CN104649937 B CN 104649937B CN 201510080270 A CN201510080270 A CN 201510080270A CN 104649937 B CN104649937 B CN 104649937B
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Description
化合物 | EC50(nM) |
实施例1化合物 | 20.9 |
实施例2化合物 | 7.7 |
实施例3化合物 | 9.3 |
实施例4化合物 | 18.4 |
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CN104649937A CN104649937A (zh) | 2015-05-27 |
CN104649937B true CN104649937B (zh) | 2016-04-13 |
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JP2976836B2 (ja) * | 1995-03-06 | 1999-11-10 | 日本製紙株式会社 | 感熱記録シート |
MXPA02010231A (es) * | 2001-11-27 | 2004-12-13 | Warner Lambert Co | Inhibidores aminotransferasa dependientes de aminoacidos de cadena ramificada y su uso en el tratamiento de las enfermedades neurodegenerativas. |
CN102397257A (zh) * | 2010-09-17 | 2012-04-04 | 北京化工大学 | 一种超细格列本脲颗粒的制备方法 |
CN103159651B (zh) * | 2011-12-14 | 2015-06-17 | 安徽贝克联合制药有限公司 | 磺酰脲胍及其制备方法和用途 |
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Denomination of invention: Halogenated benzene sulfonyl hydrazine GPR119 agonist, preparation method and application thereof Effective date of registration: 20170816 Granted publication date: 20160413 Pledgee: Guangdong Nanhai Rural Commercial Bank branch branch of Limited by Share Ltd Pledgor: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. Registration number: 2017990000756 |
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Date of cancellation: 20190604 Granted publication date: 20160413 Pledgee: Guangdong Nanhai Rural Commercial Bank branch branch of Limited by Share Ltd Pledgor: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. Registration number: 2017990000756 |
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Effective date of registration: 20191022 Address after: 221399 north side of Qingnian East Road, Yunhe Town, Pizhou City, Xuzhou City, Jiangsu Province Patentee after: Pizhou Runhong Industry Co., Ltd. Address before: Chancheng district has 528000 Taiwan public in Guangdong province Foshan City No. 32 first floor 1636, shop No. 1637 Patentee before: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. |