CN104672116B - 一种含苯磺酰肼和腈基苯结构gpr119激动剂及其用途 - Google Patents
一种含苯磺酰肼和腈基苯结构gpr119激动剂及其用途 Download PDFInfo
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- CN104672116B CN104672116B CN201510080304.8A CN201510080304A CN104672116B CN 104672116 B CN104672116 B CN 104672116B CN 201510080304 A CN201510080304 A CN 201510080304A CN 104672116 B CN104672116 B CN 104672116B
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化合物 | EC50(nM) |
参比化合物D-1 | 20.9 |
化合物I | 11.4 |
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CN201510080304.8A CN104672116B (zh) | 2015-02-13 | 2015-02-13 | 一种含苯磺酰肼和腈基苯结构gpr119激动剂及其用途 |
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CN104672116A CN104672116A (zh) | 2015-06-03 |
CN104672116B true CN104672116B (zh) | 2016-06-01 |
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US20130184257A1 (en) * | 2010-09-17 | 2013-07-18 | Thomas Daniel Aicher | Piperidinyl-substituted lactams as gpr119 modulators |
WO2014074700A1 (en) * | 2012-11-08 | 2014-05-15 | Arena Pharmaceuticals, Inc. | Antagonists of gpr119 receptor and the treatment of disorders related thereto |
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Denomination of invention: GPR119 agonist containing benzenesulfonyl hydrazine and cyanobenzene structures and application thereof Effective date of registration: 20170816 Granted publication date: 20160601 Pledgee: Guangdong Nanhai Rural Commercial Bank branch branch of Limited by Share Ltd Pledgor: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. Registration number: 2017990000756 |
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Date of cancellation: 20190604 Granted publication date: 20160601 Pledgee: Guangdong Nanhai Rural Commercial Bank branch branch of Limited by Share Ltd Pledgor: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. Registration number: 2017990000756 |
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