CN104644691A - Method for improving taste of periplaneta americana powder - Google Patents

Method for improving taste of periplaneta americana powder Download PDF

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Publication number
CN104644691A
CN104644691A CN201510096324.4A CN201510096324A CN104644691A CN 104644691 A CN104644691 A CN 104644691A CN 201510096324 A CN201510096324 A CN 201510096324A CN 104644691 A CN104644691 A CN 104644691A
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CN
China
Prior art keywords
periplaneta americana
powder
americana powder
milk
mouthfeel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510096324.4A
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Chinese (zh)
Inventor
李诗标
苏静
许翠萍
牛凤菊
刘圣梅
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jinan Kangzhong Pharmaceutical Research and Development Co Ltd
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Jinan Kangzhong Pharmaceutical Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Jinan Kangzhong Pharmaceutical Research and Development Co Ltd filed Critical Jinan Kangzhong Pharmaceutical Research and Development Co Ltd
Priority to CN201510096324.4A priority Critical patent/CN104644691A/en
Publication of CN104644691A publication Critical patent/CN104644691A/en
Pending legal-status Critical Current

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Abstract

The invention relates to a method for improving taste of periplaneta americana powder. The method is characterized in that the periplaneta americana powder is evenly mixed with milk and then is orally taken. According to the method, the periplaneta americana powder is small in oral odor, good in taste and high in compliance of a patient on the premise that the original curative effect of the periplaneta americana powder is kept.

Description

A kind of method improving Periplaneta Americana powder mouthfeel
Invention field
The present invention relates to medicine, particularly a kind of method improving Periplaneta Americana powder mouthfeel, belong to medical art.
Background technology
Periplaneta americana belongs to Insecta, Blattaria Blattidae animal, and " Blatta seu periplaneta " is loaded in Shennong's Herbal for its popular name, the beginning of being used as medicine, and is listed in middle product, meaning " taste: salty, cold; Control: the hard cold and heat of Blood stasis, removing mass are poly-, laryngopharynx numbness, endogenous cold loss of fecundity ".Now there are some researches show, the large sickle in America has and has good tissue repair activity to various traumatic surface and digestive tract ulcer; There is boosting, improve sanguimotor activity; There is the activity of anti-bacteria and anti-virus; There is antitumor, strengthen immunologic function activity.
Medicine prepared by periplaneta americana, particularly powder, takes after mixing it with water with warm water, and abnormal flavour is extra heavy, and mouthfeel is very poor, directly affects the compliance of patient.Over the past thousands of years, people always encourage patient medication with " good medicine tastes bitter ".But the reality of society is, people hang back in face of good medicine bitter to the taste, even talk " hardship " complexion changed.To medicine prepared by periplaneta americana, particularly powder, " keeping someone at a respectful distance ".Under the former medicable prerequisite of maintenance Periplaneta Americana powder, realize " good medicine is not bitter ", very necessary and urgent.
Summary of the invention
The object of this invention is to provide a kind of method improving Periplaneta Americana powder mouthfeel.
The present invention is achieved in that
Improve a method for Periplaneta Americana powder mouthfeel, it is characterized in that: get Periplaneta Americana powder, take after mixing well with milk.
A kind of method improving Periplaneta Americana powder mouthfeel of the present invention, is characterized in that replacing with: get Periplaneta Americana powder, adds milk powder, take after mixing well with water.
So far complete the present invention, instructions of taking of the present invention, under the former medicable prerequisite of maintenance Periplaneta Americana powder, oral abnormal flavour is little, and mouthfeel is good, and the compliance of patient is high.
Test example is intended to further illustrate usefulness of the present invention below, but not limitation of the present invention.
Test example one, different instructions of taking mouthfeel compare
1, instructions of taking is divided into two kinds: one gets periplaneta americana powder, takes after mixing well with warm milk; One gets periplaneta americana powder, takes after mixing well with warm water.
2, evaluation methodology is in the mouthfeel of medicine is evaluated, and sensory evaluation plays mastery reaction, and the sensation of people affects greatly by subjective factors, and language performance feels to have ambiguity, is difficult to use data representation accurately.This experiment is made up of 30 people appraises group through discussion, and everyone is oral by two kinds of methods respectively, evaluates the mouthfeel misty idea such as " very well ", " better ", " can accept ", " poor ", " very poor ".
3, evaluation result is in table 1
The different instructions of taking mouthfeel of table 1 compares
Very well Better Can accept Poor Very poor
Take after mixing well with warm milk 5 people 16 people 9 people
Take after mixing well with warm water 1 people 3 people 26 people
Result shows, and the mouthfeel that powder milk prepared by periplaneta americana is taken after mixing well is good.
Test example two, different instructions of taking compare the protective effect that ethanol causes gastric mucosa damage.
Choose healthy SD rat, male and female half and half, weight 180-220g, be divided into that rear gavage group mixed well by Periplaneta Americana powder milk, Periplaneta Americana powder water mixes well rear gavage group, matched group at random, often organize 10, every day gastric infusion 1 time, 1 2mg/kg, continuous 7 days, matched group gave equivalent distilled water.Before experiment, the first fasting 48h of rat, freely drinks water, after last administration, 1h every rat oral gavage dehydrated alcohol 1mL/ only, take off cervical vertebra after 1h and put to death animal, close cardia by clip, inject 1% formaldehyde 5mL from pylorus, folder closes pylorus again, put into 1% formalin and fix 10min, cut off coat of the stomach along greater gastric curvature, measure damaged length, as gastric mucosal damage index, and suppression ratio is calculated using damaged length (width is greater than 1 mm to be doubled) summation.The results are shown in Table 2.
Suppression ratio (%)=(matched group ulcer index one administration group ulcer index) ÷ matched group ulcer index × 100%.
The different instructions of taking of table 2 compares the protective effect that ethanol causes gastric mucosa damage
Group Dosage Gastric mucosal damage index (mm) Suppression ratio (%)
Matched group 99.4±25.4
Rear gavage group mixed well by milk 2mg/kg 56.3±19.6 43.36
Water mixes well rear gavage group 2mg/kg 56.4±19.9 43.26
Result shows, the protective effect that periplaneta americana powder two kinds of instructions of taking cause gastric mucosa damage to ethanol is suitable, illustrates that Periplaneta Americana powder milk is taken after mixing well, maintains original curative effect.
Test example three, different instructions of taking liver protective effect compare
This test adopts CCl 4the impact test of caused Liver Damage in Rats.
The healthy SD rat of body weight 180-220g, is divided into periplaneta americana powder milk to mix well rear gavage group at random, periplaneta americana powder water mixes well rear gavage group, matched group, often organizes 10; Contrast with test group in experiment the 1st, 5 days subcutaneous injection 50%CCl 4vegetable oil suspension 5mL/kg, difference gastric infusion every day 1 time from experiment starts day, 1 3g/kg, matched group gives equivalent distilled water, continuous 9 days, and drug withdrawal 24 hours eye sockets get blood, survey serum glutamic pyruvic transminase with reitman-frankel method.The results are shown in Table 3.
The different instructions of taking of table 3 is to CCl 4the impact of hepatic injury rat blood serum glutamate pyruvate transaminase
Group Dosage (g/kg) Glutamate pyruvate transaminase in serum
Matched group 377.5±120.4
Rear gavage group mixed well by temperature milk 3 187.6±102.5
Warm water mixes well rear gavage group 3 187.5±102.8
Result shows, periplaneta americana powder two kinds of instructions of taking are to rat CCl 4the protective effect of hepatic injury is suitable, illustrates that medicine milk prepared by periplaneta americana is taken after mixing well, maintains original curative effect.
Detailed description of the invention
embodiment 1
Get powder 2g prepared by periplaneta americana, mix well with 10ml milk, oral abnormal flavour is little, and mouthfeel is good.
embodiment 2
Get periplaneta americana powder 5g, mix well with 50ml milk, oral free from extraneous odour, mouthfeel is good.
embodiment 3
Get periplaneta americana powder 5g, add milk powder 2g, add warm water and mix well, oral free from extraneous odour, mouthfeel is good.
embodiment 4
Get periplaneta americana powder 5g, mix well with 100ml milk, oral free from extraneous odour, mouthfeel is good.
embodiment 5
Get periplaneta americana powder 5g, add milk powder 10g, add warm water and mix well, oral free from extraneous odour, mouthfeel is good.

Claims (2)

1. improve a method for periplaneta americana powder mouthfeel, it is characterized in that: get periplaneta americana powder, take after mixing well with milk.
2. a kind of method improving periplaneta americana powder mouthfeel according to claim 1, is characterized in that replacing with: get medicine prepared by periplaneta americana, add milk powder, takes after mixing well with water.
CN201510096324.4A 2015-03-05 2015-03-05 Method for improving taste of periplaneta americana powder Pending CN104644691A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510096324.4A CN104644691A (en) 2015-03-05 2015-03-05 Method for improving taste of periplaneta americana powder

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510096324.4A CN104644691A (en) 2015-03-05 2015-03-05 Method for improving taste of periplaneta americana powder

Publications (1)

Publication Number Publication Date
CN104644691A true CN104644691A (en) 2015-05-27

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Family Applications (1)

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CN201510096324.4A Pending CN104644691A (en) 2015-03-05 2015-03-05 Method for improving taste of periplaneta americana powder

Country Status (1)

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CN (1) CN104644691A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103891895A (en) * 2012-12-31 2014-07-02 内蒙古伊利实业集团股份有限公司 Liquid dairy product containing earthworm protein and preparation method of liquid dairy product

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103891895A (en) * 2012-12-31 2014-07-02 内蒙古伊利实业集团股份有限公司 Liquid dairy product containing earthworm protein and preparation method of liquid dairy product

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Application publication date: 20150527