CN104644680A - Preparation method of earthworm powder without peculiar taste - Google Patents
Preparation method of earthworm powder without peculiar taste Download PDFInfo
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- CN104644680A CN104644680A CN201510096299.XA CN201510096299A CN104644680A CN 104644680 A CN104644680 A CN 104644680A CN 201510096299 A CN201510096299 A CN 201510096299A CN 104644680 A CN104644680 A CN 104644680A
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Abstract
The invention provides a preparation method of earthworm powder without peculiar taste. Milk powder is added and crushed together with the earthworm powder. The prepared earthworm powder has the advantages of little peculiar taste in oral taking, good mouthfeel and high compliance of patients.
Description
Invention field
The present invention relates to medicine, particularly a kind of preparation method of free from extraneous odour Pheretima powder, belong to medical art.
Background technology
Pheretima is the dry body of Annelida Ju Yin section animal Pheretima aspergillum, popular Pheretimatschiliensis, power simulation or comb the region between the heart and the diaphragm hair earthworm.Front one is practised and is claimed " LUMBRICUS ", practises title " Lu Pheretima " for latter three kinds.LUMBRICUS catches to autumn spring, and Lu Pheretima catches summer, cuts abdominal part open in time, and removing internal organs and silt are cleaned, dried or cold drying;
Pheretima has heat clearing away arresting convulsion, dredging collateral, relievings asthma, effect of diuresis.For unconsciousness due to high fever, frightened carbuncle is twitched, and joint is benumbed, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, edema oliguria etc.Modern study finds that Pheretima also has the effect such as antithrombotic, antitumor, immunity moderation, blood pressure lowering, arrhythmia, easing pain and diminishing inflammation.Pheretima powder warm water is taken after mixing it with water, and abnormal flavour is extra heavy, and mouthfeel is very poor, directly affects the compliance of patient.A kind of method improving Pheretima powder mouthfeel is provided, very necessary.
Summary of the invention
The object of this invention is to provide a kind of preparation method of free from extraneous odour Pheretima powder.
The object of the present invention is achieved like this:
A preparation method for free from extraneous odour Pheretima powder, is characterized in that: add milk powder and together pulverize.
The preparation method of a kind of free from extraneous odour Pheretima powder of the present invention, is characterized in that: the amount adding milk powder is more than 0.1 times by weight.
The preparation method of a kind of free from extraneous odour Pheretima powder of the present invention, is characterized in that: the amount adding milk powder is more than 0.5-3 times by weight.
The preparation method of a kind of free from extraneous odour Pheretima of the present invention, is characterized in that: the amount adding milk powder is 1 times by weight.
A preparation method for free from extraneous odour Pheretima powder, is characterized in that: be optimized for flavoring agent conventional in milk and galenic pharmacy further; Wherein conventional in galenic pharmacy flavoring agent is sweeting agent, flavouring agent, acidic flavoring agent etc.
The preparation method of a kind of free from extraneous odour Pheretima of the present invention, is characterized in that: replace with and add milk powder in Pheretima powder.
The preparation method of a kind of free from extraneous odour Pheretima of the present invention, is characterized in that: replace with and add flavoring agent conventional in milk powder and galenic pharmacy in Pheretima powder.
So far the present invention is completed.The preparation method of a kind of free from extraneous odour Pheretima powder of the present invention, under the prerequisite keeping the original curative effect of Pheretima, oral abnormal flavour is little, and mouthfeel is good, and the compliance of patient is high.
Below by test example, usefulness of the present invention is described.Test example is intended to further illustrate beneficial effect of the present invention, but not restriction of the present invention.
Pheretima powder mouthfeel prepared by test example one, distinct methods compares
1, with a collection of dry Pheretima, will prepare by the following method respectively.
1) directly pulverize;
2) add milk powder to pulverize: add 0.1 times of milk powder, pulverize.
2, mouthfeel compares
Be made up of 10 people and appraise group through discussion, everyone warm water for oral use direct pulverizing of mixing well and add the Pheretima powder that milk powder pulverizes respectively, evaluates the mouthfeel mouthfeel such as " very well ", " better ", " can accept ", " poor ", " very poor ".Evaluation result is in table 1
Pheretima powder mouthfeel powder mouthfeel prepared by table 1 distinct methods compares
| Very well | Better | Can accept | Poor | Very poor | |
| Add milk powder to pulverize | 0 people | 5 people | 5 people | 0 people | 0 people |
| Direct pulverizing | 0 people | 0 people | 0 people | 2 people | 8 people |
Result shows, and Pheretima adds milk powder and pulverizes, and oral abnormal flavour is little, and mouthfeel is good.
The Pheretima powder antiasthmatic effect of test example two, distinct methods processing compares
1, with a collection of dry Pheretima, will prepare by the following method respectively.
1) directly pulverize;
2) add milk powder to pulverize: add 0.5 times of milk powder, pulverize.
2, the different instructions of taking antiasthmatic effect of Pheretima powder compares
Acetylcholine draws to be breathed heavily test and chooses weight 200-250 g Cavia porcellus, puts respectively in automiser spray, sprays into containing 1mg/ml acecoline solution with soniclizer with same intensity, and spraying 15s Cavia porcellus, through one period of incubation period, produces asthma.Will not selecting of asthma is not produced more than 60 s.Then 3 groups are divided at random, often organize 10, be respectively negative control group normal saline 10 ml/kg, direct pulverizing group (0.35 g/kg), add milk powder pulverizing group (0.35 g/ kg, with Pheretima content meter), each group of equal gastric infusion, mixing well volume with normal saline is 10m1/kg, after administration 30min, put into sprayer unit respectively and spray into acecoline solution respectively by preliminary election similarity condition, record spraying starts to the time that symptoms of asthma occurs as latent time, observe 3min, the asthmatic latent period without asthma calculates with 3min.The results are shown in Table 2.
Table 2 Pheretima powder different processing methods antiasthmatic effect compares
| Negative control group | Add milk powder to pulverize | Direct pulverizing | |
| Dosage | 0 | 0.35g/kg | 0.35g/kg |
| Incubation period (s) | 54±6 | 75±6 | 75±7 |
Result shows, Pheretima powder has good antiasthmatic effect, and the Pheretima adding milk powder pulverizing is suitable with the Pheretima effect directly pulverized.
The Pheretima powder anticoagulation test of test example three, distinct methods processing
1, with a collection of dry Pheretima, will prepare by the following method respectively.
1) directly pulverize;
2) add milk powder to pulverize: add 1 times of milk powder, pulverize.
2, the Pheretima powder anticoagulation test of distinct methods processing
Mice 30, be divided into 3 groups at random, often organize 10, be respectively negative control group reason saline 10 ml/kg, directly pulverizing group (0.35 g/kg), adds milk powder pulverizing group (0.35 g/ kg, with Pheretima content meter), each group of equal gastric infusion, mixing well volume with property reason saline is 10m1/kg, and successive administration 3d measures clotting time by capillary glass-tube method after last administration 30min.The results are shown in Table 3.
The Pheretima anticoagulant effect of table 3 distinct methods processing compares
| Negative control group | Add milk powder to pulverize | Direct pulverizing | |
| Dosage | 0 | 10g/ kg | 10g/ kg |
| Clotting time (s) | 102±12 | 125±16 | 125±15 |
Result shows, the Pheretima powder antithrombin activity prepared by pure land dragon calculating two kinds of methods is suitable, illustrates and adds the curative effect that milk powder does not affect Pheretima.
Detailed description of the invention
embodiment 1
Dry Pheretima 2kg, adds milk powder 0.2kg, mixing, pulverizes, obtains free from extraneous odour Pheretima powder.
embodiment 2
Dry Pheretima 2kg, adds milk powder 2kg, mixing, pulverizes, obtains free from extraneous odour Pheretima powder.
embodiment 3
Dry Pheretima 2kg, adds milk powder 1kg, mixing, pulverizes, obtains free from extraneous odour Pheretima powder.
embodiment 4
Dry Pheretima 2kg, adds milk powder 6kg, mixing, pulverizes, obtains free from extraneous odour Pheretima powder.
embodiment 5
Dry Pheretima 2kg, adds milk powder 0.5kg, glucose 0.5kgg, mixing, pulverizes, obtains free from extraneous odour Pheretima powder.
embodiment 6
Dry Pheretima 2kg, adds milk powder 15kg, glucose 30g, saccharin sodium 3g, vanillin 1g, mixing, pulverizes, obtains free from extraneous odour Pheretima powder.
embodiment 7
Dry Pheretima 2kg, adds milk powder 20kg, saccharin sodium 3g, vanillin 2g, mixing, pulverizes, obtains free from extraneous odour Pheretima powder.
embodiment 8
Pheretima powder 2kg, milk powder 20kg, saccharin sodium 3g, vanillin 2g, mixing, obtains free from extraneous odour Pheretima powder.
embodiment 9
Pheretima powder 2kg, milk powder 0.2kg, mixing, obtains free from extraneous odour Pheretima powder.
Claims (7)
1. a preparation method for free from extraneous odour Pheretima powder, is characterized in that: add milk powder and together pulverize.
2. the preparation method of a kind of free from extraneous odour Pheretima powder according to claim 1, is characterized in that: the amount adding milk powder is more than 0.1 times by weight.
3. according to the preparation method of a kind of free from extraneous odour Pheretima powder of claim 1 or claim 2, it is characterized in that: the amount adding milk powder is 0.5-3 times by weight.
4., according to the preparation method of a kind of free from extraneous odour Pheretima of claim 1 or claim 2 or claim 3, it is characterized in that: the amount adding milk powder is 1 times by weight.
5. a preparation method for free from extraneous odour Pheretima powder, is characterized in that: add flavoring agent conventional in milk and galenic pharmacy; Wherein conventional in galenic pharmacy flavoring agent is sweeting agent, flavouring agent, acidic flavoring agent etc.
6., according to the preparation method of a kind of free from extraneous odour Pheretima of claim 1 or claim 2 or claim 3 or claim 4, it is characterized in that: replace with and add milk powder in Pheretima powder.
7. the preparation method of a kind of free from extraneous odour Pheretima according to claim 5, is characterized in that: replace with and add flavoring agent conventional in milk powder and galenic pharmacy in Pheretima powder.
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| CN201510096299.XA CN104644680A (en) | 2015-03-05 | 2015-03-05 | Preparation method of earthworm powder without peculiar taste |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107495214A (en) * | 2017-09-18 | 2017-12-22 | 江苏步龙生物科技有限公司 | A kind of compound earthworm powder and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103891895A (en) * | 2012-12-31 | 2014-07-02 | 内蒙古伊利实业集团股份有限公司 | Liquid dairy product containing earthworm protein and preparation method of liquid dairy product |
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2015
- 2015-03-05 CN CN201510096299.XA patent/CN104644680A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103891895A (en) * | 2012-12-31 | 2014-07-02 | 内蒙古伊利实业集团股份有限公司 | Liquid dairy product containing earthworm protein and preparation method of liquid dairy product |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107495214A (en) * | 2017-09-18 | 2017-12-22 | 江苏步龙生物科技有限公司 | A kind of compound earthworm powder and preparation method thereof |
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Application publication date: 20150527 |
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