CN104642688A - Preparation method of cordyceps militaris link tableted candy - Google Patents
Preparation method of cordyceps militaris link tableted candy Download PDFInfo
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- CN104642688A CN104642688A CN201510082107.XA CN201510082107A CN104642688A CN 104642688 A CN104642688 A CN 104642688A CN 201510082107 A CN201510082107 A CN 201510082107A CN 104642688 A CN104642688 A CN 104642688A
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Abstract
The invention relates to a preparation method of a cordyceps militaris link tableted candy. The preparation method comprises the following steps: (1) carrying out superfine grinding, namely grinding all dried cordyceps militaris with superfine grinding equipment by the low-temperature grinding technology until the granularity of 90.0% of ground material is less than or equal to 25mu m; (2) mixing and granulating, namely uniformly mixing lactose, mannite, maltodextrin and cordyceps militaris superfine powder in the step (1) in certain mass ratio, and adding with water for granulating rapidly; (3) drying secondarily; (4) screening and shaping; (5) mixing, namely mixing the mixed particles in the step (4) with magnesium stearate uniformly to be tableted; and (6) tableting, namely tableting the mixed material in the step (5) to obtain a finished product. According to the preparation method, the tableted candy has high effective constituent after superfine grinding of the cordyceps militaris, the effective constituents can be released rapidly and completely, the medicinal material is not wasted and rational and efficient health-care effect can be achieved easily.
Description
Technical field
The present invention relates to the preparation method of Cordyceps militaris product, particularly relate to a kind of preparation method of fruiting bodies of cordyceps militaris pressed candy.
Background technology
Cordyceps militaris has another name called northern Chinese caterpillar Fungus, Cordyceps militaris etc., belongs to Ascomycotina Clavicipitaceae Cordyceps, belongs to xenogenesis together with Cordyceps sinensis.Research display: the cordyceps militaris fruit body of artificial culture and natural Cordyceps sinensis organic with inorganic nutritive element kind on basically identical, but northern Chinese caterpillar Fungus is higher than the content of natural cordyceps on main functional component.If cordycepin is the distinctive functional component of Cordyceps sinensis, northern Chinese caterpillar Fungus is 35 times of wild cordyceps, and adenine is 40 times of wild cordyceps, and ucleosides total amount is 6.25 times of wild cordyceps.Cordycepin has effect that is antiviral, antibacterial, Tumor suppression growth, has obvious synergy, and have hypoglycemic effect with endoxan; And adenosine directly can enter cardiac muscle through phosphorylation and generates adenylate, participate in energy metabolism of myocardial, to cardiovascular system unify body other systems many and organize and all have obvious physiological action.
Current Cordyceps militaris product on the market, a class is coarse crushing product, and raw material is through the capsule, tea in bag etc. of coarse crushing aft-loaded airfoil.Cordyceps militaris product after coarse crushing processing, its active ingredient rate of release is slow, and release not exclusively, is difficult to play efficient and rational health-care effect.Because autonomic drug, animal the effective elements of the medicine are mainly distributed in cell and cytoplasm, ultramicro grinding can make Cordyceps militaris diameter of particle reach micron order, the cell membrane of effective broken Chinese medicine, intracellular active ingredient fully comes out, rate of release and releasing degree all can be greatly enhanced.Another kind of is extract series products, and Cordyceps militaris concentrated obtains extract through extracting, then through series of process flow process or add the drink etc. that other medicinal material obtains.And extract in concentration process at this, Cordyceps militaris is extracted through the decoction of repeatedly pressurizeing, and long concentrate drying, active ingredient in Cordyceps militaris is through heating of heating for a long time, can cause the greater loss of active ingredient, simultaneously in leaching process, a large amount of waste water, waste gas produce, while being unfavorable for environmental protection, eliminating waste water, waste gas production cost is compared can be higher.
In addition, Cordyceps militaris product on the market at present, more product main component in other words conj.or perhaps main medicinal material is Cordyceps militaris one.
Summary of the invention
The object of the invention is to overcome the preparation method that above deficiency and defect propose a kind of fruiting bodies of cordyceps militaris pressed candy.
For reaching this object, the present invention by the following technical solutions:
A preparation method for fruiting bodies of cordyceps militaris pressed candy, it comprises the following steps:
1), ultramicro grinding: granularity≤25 μm of dried Cordyceps militaris being pulverized whole material to 90.0% through Ultra-Micro Grinding Equipment, the granularity controlling material guarantees that the active ingredient of final finished can discharge completely.Adopt freeze grinding technology in crushing process, remain raw-material active ingredient to greatest extent.
2), mixing granulation: by lactose, mannitol, maltodextrin and step 1) in Cordyceps militaris Ultramicro-powder mix by certain mass ratio, then add water and granulate fast;
3), second time is dry: by step 2) obtained mixing wet granular carries out drying;
4), screening and whole grain: by step 3) dried hybrid particles sieves, the coarse granule on screen cloth, then carries out whole grain pulverizing;
5), mixing: by step 4) in hybrid particles and dolomol mix by a certain percentage, after mixing material wait until compressing tablet;
6), compressing tablet: by step 5) after mixing material carries out compressing tablet and obtains finished product.
Preferably, the recipe ingredient of described fruiting bodies of cordyceps militaris pressed candy comprises by mass percentage: Cordyceps militaris 20%-50%, lactose 10-50%, mannitol 2%-20%, maltodextrin 2%-20% and dolomol 0.3-3%.
Preferably, in step 2) in, by lactose, mannitol, maltodextrin and step 4) in Cordyceps militaris Ultramicro-powder mass ratio equal increments method be according to a certain percentage placed in fast granulating machine and mix.
Preferably, in step 3) in, mixing wet granular is laid on pallet, the tiling thickness≤3cm of hybrid particles.
Preferred further, in step 3) in, pallet is placed in hot air circulation drying oven, and arranging drying box temperature is 65-75 DEG C, dry 1.5-2.5h; Control moisture at 2%-3.5%.
Preferably, material being poured into screen cloth is 20 object shaking screen extension sets, sieves in the operating room of humidity below 40%.
Preferably, in step 5) in, by after mixing material is put into tablet press machine and is carried out compressing tablet; Control compressing tablet and focus on 550mg ± 50mg.
Beneficial effect of the present invention:
1, Cordyceps militaris is after low temperature breaking-wall cell ultramicro grinding, in cell and the active ingredient of cytoplasm fully must discharge, and due to the temperature of crushing operation active ingredient that is lower, destroyed, degraded less, active ingredient can be retained to greatest extent, save medicinal material greatly.
2, compare the Cordyceps militaris product of extraction type of commercial type, this product possesses the feature of energy-conserving and environment-protective.Owing to extracting the Cordyceps militaris food of type, the decoction through repeatedly pressurizeing is needed to extract, could by extracts active ingredients wherein out, then extract also needs finally to obtain the higher active ingredient of purity through long concentrate drying, in this extraction, concentrated, dry process, active ingredient in Cordyceps militaris, active material experienced by heating of heating for a long time, and wherein much become branch to cause larger loss in this process, some volatile ingredients are lost even completely.And also have a large amount of waste water to produce in process of production, also improve production cost not environmentally.
3, Cordyceps militaris Ultramicro-powder makes pressed candy, adds the stability of Cordyceps militaris Ultramicro-powder, moisture resistance, is conducive to storage.Be compared to graininess, powdered preparations, the relative volume of compressing tablet goods is little, and surface area is little, and be more conducive to food, the moisture resistance of medicine, stability, the shelf-life is longer.
4, taking convenience is simple, makes buccal tablet Ultramicro-powder of comparing easy to carry, takes simple.
Detailed description of the invention
Technical scheme of the present invention is further illustrated below by detailed description of the invention.
A kind of recipe ingredient of fruiting bodies of cordyceps militaris pressed candy comprises: Cordyceps militaris Ultramicro-powder 20%-50%, lactose 10-50%, mannitol 2%-20%, maltodextrin 2%-20% and dolomol 0.3%-3%.
A preparation method for fruiting bodies of cordyceps militaris pressed candy, it comprises the following steps:
1), concoct: the Cordyceps militaris chosen is removed impurity, rinses, clean out the silt on surface;
2), boiling sterilization: the Cordyceps militaris cooked is laid on pallet, is placed in steaming the medicinal hebrs case and carries out boiling sterilization; The boiling sterilization time is 30-35 minute.
3), dry: by step 2) Cordyceps militaris after sterilizing puts into hot air circulation drying oven and carries out drying; Baking temperature is 45-55 degree, and drying time is 11-13 hour, controls moisture≤5.0%.
4), ultramicro grinding: by step 3) dry after Cordyceps militaris pulverize granularity≤25 μm of whole material to 90.0% through Ultra-Micro Grinding Equipment;
5), mixing granulation: by lactose, mannitol, maltodextrin and step 4) in Cordyceps militaris Ultramicro-powder mass ratio equal increments method be according to a certain percentage placed in fast granulating machine and mix, then add appropriate water, granulate fast;
6), second time is dry: by step 5) obtained mixing wet granular is laid on pallet, the tiling thickness≤3cm of hybrid particles; Pallet is placed in hot air circulation drying oven, and arranging drying box temperature is 65-75 DEG C, dry 1.5-2.5h; Control moisture at 2%-3.5%.
7), screening and whole grain: by step 6) to pour screen cloth into be that 20 objects are shaken humidity in screening machine and sieved below 40% to dried hybrid particles, the coarse granule on screen cloth, puts into pelletizing machine and carries out whole grain pulverizing;
8), mixing: by step 7) in hybrid particles and a certain amount of dolomol mixing, after mixing material wait until compressing tablet;
9), compressing tablet: by step 8) after mixing material is poured in tablet press machine and is carried out compressing tablet; Control strip focuses on 0.5g-0.6g;
10), packing and packaging: get qualified above-mentioned material, carry out packing in the indoor of relative humidity less than 40% and external packing obtains finished product.
Superfine communication technique is that grew up in the world in the last few years one application modern physics or chemical method carry out micronized new technology to material, has been widely used in many fields such as chemical industry, medicine, food, agricultural chemicals, cosmetics.Superfine communication technique refers to and uses modern advanced pulverizing means, crushing material is become the particle of micron or even Nano grade.For Chinese medicine, pulverizing medicinal materials is become the particle of micron or even Nano grade, crude drug cell can be smashed by this comminution process, and the utilization rate of medicinal material increases substantially, and many medicinal materials can reduce dose, saves 1/3 ~ 1/2.
Superfine communication technique is different from pure mechanical crushing method in the past, hot-spot phenomenon can not be produced at crushing process, even can pulverize at low temperatures, thus the bioactive ingredients of powder is remained to greatest extent, even particle size, color and luster is consistent, and powder is fine and smooth, is conducive to improving the quality of products.In addition, ultramicro grinding also shows following advantage: the bioactive ingredients that can retain powder to greatest extent, is conducive to making required high quality of products; Conservation, increases operation rate; Reduce the pollution to environment; The uniformity of medicinal material is high.
Embodiment 1
A preparation method for fruiting bodies of cordyceps militaris pressed candy, it comprises the following steps:
1), concoct: the Cordyceps militaris chosen is removed impurity, rinses, clean out the silt on surface;
2), boiling sterilization: the Cordyceps militaris cooked is laid on pallet, is placed in steaming the medicinal hebrs case and carries out boiling sterilization; The boiling sterilization time is 30 minutes.
3), dry: by step 2) Cordyceps militaris after sterilizing puts into hot air circulation drying oven and carries out drying; Baking temperature is 45 degree, and drying time is 13 hours, controls moisture≤5.0%.
4), ultramicro grinding: by step 3) dry after Cordyceps militaris pulverize granularity≤25 μm of whole material to 90.0% through Ultra-Micro Grinding Equipment;
5), mixing granulation: by lactose 10%, mannitol 20%, maltodextrin 17% and step 4) in Cordyceps militaris Ultramicro-powder 50% be placed in fast granulating machine by equal increments method and mix, then add appropriate water, granulate fast;
6), second time is dry: by step 5) obtained mixing wet granular is laid on pallet, the tiling thickness≤3cm of hybrid particles; Pallet is placed in hot air circulation drying oven, and arranging drying box temperature is 65 DEG C, dry 2.5h; Control moisture between 2%-3.5%.
7), screening and whole grain: by step 6) to pour screen cloth into be that 20 objects are shaken humidity in screening machine and sieved below 40% to dried hybrid particles, the coarse granule on screen cloth, puts into pelletizing machine and carries out whole grain pulverizing;
8), mixing: by step 7) in hybrid particles and 3% dolomol mixing, after mixing material wait until compressing tablet;
9), compressing tablet: by step 8) after mixing material is poured in tablet press machine and is carried out compressing tablet; Control strip focuses on 550mg ± 50mg;
10), packing and packaging: get qualified above-mentioned material, carry out packing in the indoor of relative humidity less than 40% and external packing obtains finished product.
In embodiment 1, Cordyceps militaris accounting is heavily 50%, and active ingredient adenosine content is about 0.12%, and cordycepin content is about 0.15%.The rate of release of finite element is about 22 minutes.
Embodiment 2
A preparation method for fruiting bodies of cordyceps militaris pressed candy, it comprises the following steps:
1), concoct: the Cordyceps militaris chosen is removed impurity, rinses, clean out the silt on surface;
2), boiling sterilization: the Cordyceps militaris cooked is laid on pallet, is placed in steaming the medicinal hebrs case and carries out boiling sterilization; The boiling sterilization time is 31 minutes.
3), dry: by step 2) Cordyceps militaris after sterilizing puts into hot air circulation drying oven and carries out drying; Baking temperature is 55 degree, and drying time is 11 hours, controls moisture≤5.0%.
4), ultramicro grinding: by step 3) dry after Cordyceps militaris pulverize granularity≤25 μm of whole material to 90.0% through Ultra-Micro Grinding Equipment;
5), mixing granulation: by lactose 50%, mannitol 18%, maltodextrin 10% and step 4) in Cordyceps militaris Ultramicro-powder 20% be placed in fast granulating machine by equal increments method and mix, then add appropriate water, granulate fast;
6), second time is dry: by step 5) obtained mixing wet granular is laid on pallet, the tiling thickness≤3cm of hybrid particles; Pallet is placed in hot air circulation drying oven, and arranging drying box temperature is 75 DEG C, dry 1.5h; Control moisture between 2%-3.5%.
7), screening and whole grain: by step 6) to pour screen cloth into be that 20 objects are shaken humidity in screening machine and sieved below 40% to dried hybrid particles, the coarse granule on screen cloth, puts into pelletizing machine and carries out whole grain pulverizing;
8), mixing: by step 7) in hybrid particles and 2% dolomol mixing, after mixing material wait until compressing tablet;
9), compressing tablet: by step 8) after mixing material is poured in tablet press machine and is carried out compressing tablet; Control strip focuses on 0.5g;
10), packing and packaging: get qualified above-mentioned material, carry out packing in the indoor of relative humidity less than 40% and external packing obtains finished product.
In embodiment 2, Cordyceps militaris accounting is heavily 25%, and active ingredient adenosine content is about 0.06%, and cordycepin content is about 0.08%.The rate of release of finite element is about 20 minutes.
Embodiment 3
A preparation method for fruiting bodies of cordyceps militaris pressed candy, it comprises the following steps:
1), concoct: the Cordyceps militaris chosen is removed impurity, rinses, clean out the silt on surface;
2), boiling sterilization: the Cordyceps militaris cooked is laid on pallet, is placed in steaming the medicinal hebrs case and carries out boiling sterilization; The boiling sterilization time is 32 minutes.
3), dry: by step 2) Cordyceps militaris after sterilizing puts into hot air circulation drying oven and carries out drying; Baking temperature is 50 degree, and drying time is 12 hours, controls moisture≤5.0%.
4), ultramicro grinding: by step 3) dry after Cordyceps militaris pulverize granularity≤25 μm of whole material to 90.0% through Ultra-Micro Grinding Equipment;
5), mixing granulation: by lactose 29%, mannitol 10%, maltodextrin 20% and step 4) in Cordyceps militaris Ultramicro-powder 40.7% be placed in fast granulating machine by equal increments method and mix, then add appropriate water, granulate fast;
6), second time is dry: by step 5) obtained mixing wet granular is laid on pallet, the tiling thickness≤3cm of hybrid particles; Pallet is placed in hot air circulation drying oven, and arranging drying box temperature is 70 DEG C, dry 2h; Control moisture between 2.0%-3.5%.
7), screening and whole grain: by step 6) to pour screen cloth into be that 20 objects are shaken humidity in screening machine and sieved below 40% to dried hybrid particles, the coarse granule on screen cloth, puts into pelletizing machine and carries out whole grain pulverizing;
8), mixing: by step 7) in hybrid particles and 0.3% dolomol mixing, mix rear gained material and wait until compressing tablet;
9), compressing tablet: by step 8) after mixing material is poured in tablet press machine and is carried out compressing tablet; Heavy 550mg ± the 50mg of control strip;
10), packing and packaging: get qualified above-mentioned material, carry out packing in the indoor of relative humidity less than 40% and external packing obtains finished product.
In embodiment 3, Cordyceps militaris accounting is heavily 40%, and active ingredient adenosine content is about 0.10%, and cordycepin content is about 0.12%.The rate of release of finite element is about 21 minutes.
Embodiment 4
A preparation method for fruiting bodies of cordyceps militaris pressed candy, it comprises the following steps:
1), concoct: the Cordyceps militaris chosen is removed impurity, rinses, clean out the silt on surface;
2), boiling sterilization: the Cordyceps militaris cooked is laid on pallet, is placed in steaming the medicinal hebrs case and carries out boiling sterilization; The boiling sterilization time is 33 minutes.
3), dry: by step 2) Cordyceps militaris after sterilizing puts into hot air circulation drying oven and carries out drying; Baking temperature is 54 degree, and drying time is 11.5 hours, controls moisture≤5.0%.
4), ultramicro grinding: by step 3) dry after Cordyceps militaris pulverize granularity≤25 μm of whole material to 90.0% through Ultra-Micro Grinding Equipment;
5), mixing granulation: by lactose 35%, mannitol 15%, maltodextrin 15% and step 4) in Cordyceps militaris Ultramicro-powder 32% mass ratio equal increments method be according to a certain percentage placed in fast granulating machine and mix, then add appropriate water, granulate fast;
6), second time is dry: by step 5) obtained mixing wet granular is laid on pallet, the tiling thickness≤3cm of hybrid particles; Pallet is placed in hot air circulation drying oven, and arranging drying box temperature is 65-75 DEG C, dry 1.5-2.5h; Control moisture at 2%-3.5%.
7), screening and whole grain: by step 6) to pour screen cloth into be that 20 objects are shaken humidity in screening machine and sieved below 40% to dried hybrid particles, the coarse granule on screen cloth, puts into pelletizing machine and carries out whole grain pulverizing;
8), mixing: by step 7) in hybrid particles and 3% dolomol mixing, after mixing material wait until compressing tablet;
9), compressing tablet: by step 8) after mixing material is poured in tablet press machine and is carried out compressing tablet; Control strip focuses on 550mg ± 50mg;
10), packing and packaging: get qualified above-mentioned material, carry out packing in the indoor of relative humidity less than 40% and external packing obtains finished product.
In embodiment 4, Cordyceps militaris accounting is heavily 35%, and active ingredient adenosine content is about 0.09%, and cordycepin content is about 0.11%.The rate of release of finite element is about 21 minutes.
Embodiment 5
A preparation method for fruiting bodies of cordyceps militaris pressed candy, it comprises the following steps:
1), concoct: the Cordyceps militaris chosen is removed impurity, rinses, clean out the silt on surface;
2), boiling sterilization: the Cordyceps militaris cooked is laid on pallet, is placed in steaming the medicinal hebrs case and carries out boiling sterilization; The boiling sterilization time is 34 minutes.
3), dry: by step 2) Cordyceps militaris after sterilizing puts into hot air circulation drying oven and carries out drying; Baking temperature is 48 degree, and drying time is 12.5 hours, controls moisture≤5.0%.
4), ultramicro grinding: by step 3) dry after Cordyceps militaris pulverize granularity≤25 μm of whole material to 90.0% through Ultra-Micro Grinding Equipment;
5), mixing granulation: by lactose 41%, mannitol 2%, maltodextrin 7% and step 4) in Cordyceps militaris Ultramicro-powder 48% mass ratio equal increments method be according to a certain percentage placed in fast granulating machine and mix, then add appropriate water, granulate fast;
6), second time is dry: by step 5) obtained mixing wet granular is laid on pallet, the tiling thickness≤3cm of hybrid particles; Pallet is placed in hot air circulation drying oven, and arranging drying box temperature is 72 DEG C, dry 1.8h; Control moisture at 2.0%-3.2%.
7), screening and whole grain: by step 6) to pour screen cloth into be that 20 objects are shaken humidity in screening machine and sieved below 40% to dried hybrid particles, the coarse granule on screen cloth, puts into pelletizing machine and carries out whole grain pulverizing;
8), mixing: by step 7) in hybrid particles and 2% dolomol mixing, after mixing material wait until compressing tablet;
9), compressing tablet: by step 8) after mixing material is poured in tablet press machine and is carried out compressing tablet; Control strip focuses on 550mg ± 50mg;
10), packing and packaging: get qualified above-mentioned material, carry out packing in the indoor of relative humidity less than 40% and external packing obtains finished product.
In embodiment 5, Cordyceps militaris accounting is heavily 45%, and active ingredient adenosine content is about 0.11%, and cordycepin content is about 0.14%.The rate of release of finite element is about 25 minutes.
Embodiment 6
A preparation method for fruiting bodies of cordyceps militaris pressed candy, it comprises the following steps:
1), concoct: the Cordyceps militaris chosen is removed impurity, rinses, clean out the silt on surface;
2), boiling sterilization: the Cordyceps militaris cooked is laid on pallet, is placed in steaming the medicinal hebrs case and carries out boiling sterilization; The boiling sterilization time is 35 minutes.
3), dry: by step 2) Cordyceps militaris after sterilizing puts into hot air circulation drying oven and carries out drying; Baking temperature is 45-55 degree, and drying time is 11-13 hour, controls moisture≤5.0%.
4), ultramicro grinding: by step 3) dry after Cordyceps militaris pulverize granularity≤25 μm of whole material to 90.0% through Ultra-Micro Grinding Equipment;
5), mixing granulation: just lactose 44%, mannitol 18%, maltodextrin 2% and step 4) in Cordyceps militaris Ultramicro-powder 35% ratio equal increments method be placed in fast granulating machine and mix, then add appropriate water, granulate fast;
6), second time is dry: by step 5) obtained mixing wet granular is laid on pallet, the tiling thickness≤3cm of hybrid particles; Pallet is placed in hot air circulation drying oven, and arranging drying box temperature is 68 DEG C, dry 2.2h; Control moisture 2%.
7), screening and whole grain: by step 6) to pour screen cloth into be that 20 objects are shaken humidity in screening machine and sieved below 40% to dried hybrid particles, the coarse granule on screen cloth, puts into pelletizing machine and carries out whole grain pulverizing;
8), mixing: by step 7) in hybrid particles and 1% dolomol mixing, after mixing material wait until compressing tablet;
9), compressing tablet: by step 8) after mixing material is poured in tablet press machine and is carried out compressing tablet; Heavy 550mg ± the 50mg of control strip;
10), packing and packaging: get qualified above-mentioned material, carry out packing in the indoor of relative humidity less than 40% and external packing obtains finished product.
In embodiment 6, Cordyceps militaris accounting is heavily 35%, and active ingredient adenosine content is about 0.09%, and cordycepin content is about 0.11%.The rate of release of finite element is about 23 minutes.
Embodiment 7
A preparation method for fruiting bodies of cordyceps militaris pressed candy, it comprises the following steps:
1), concoct: the Cordyceps militaris chosen is removed impurity, rinses, clean out the silt on surface;
2), boiling sterilization: the Cordyceps militaris cooked is laid on pallet, is placed in steaming the medicinal hebrs case and carries out boiling sterilization; The boiling sterilization time is 32 minutes.
3), dry: by step 2) Cordyceps militaris after sterilizing puts into hot air circulation drying oven and carries out drying; Baking temperature is 49 degree, and drying time is 12 hours, controls moisture≤5.0%.
4), ultramicro grinding: by step 3) dry after Cordyceps militaris pulverize granularity≤25 μm of whole material to 90.0% through Ultra-Micro Grinding Equipment;
5), mixing granulation: by lactose 31%, mannitol 6%, maltodextrin 18.5% and step 4) in Cordyceps militaris Ultramicro-powder 44% be placed in fast granulating machine by equal increments method and mix, then add appropriate water, granulate fast;
6), second time is dry: by step 5) obtained mixing wet granular is laid on pallet, the tiling thickness≤3cm of hybrid particles; Pallet is placed in hot air circulation drying oven, and arranging drying box temperature is 73 DEG C, dry 1.7h; Control moisture between 2.0%-3.5%.
7), screening and whole grain: by step 6) to pour screen cloth into be that 20 objects are shaken humidity in screening machine and sieved below 40% to dried hybrid particles, the coarse granule on screen cloth, puts into pelletizing machine and carries out whole grain pulverizing;
8), mixing: by step 7) in hybrid particles and 0.5% dolomol mixing, after mixing material wait until compressing tablet;
9), compressing tablet: by step 8) after mixing material is poured in tablet press machine and is carried out compressing tablet; Control strip focuses on 550mg ± 50mg;
10), packing and packaging: get qualified above-mentioned material, carry out packing in the indoor of relative humidity less than 40% and external packing obtains finished product.
In embodiment 7, Cordyceps militaris accounting is heavily 48.5%, and active ingredient adenosine content is about 0.12%, and cordycepin content is about 0.15%.The rate of release of finite element is about 23 minutes.
Below know-why of the present invention is described in conjunction with specific embodiments.These describe just in order to explain principle of the present invention, and can not be interpreted as limiting the scope of the invention by any way.Based on explanation herein, those skilled in the art does not need to pay performing creative labour can associate other detailed description of the invention of the present invention, and these modes all will fall within protection scope of the present invention.
Claims (7)
1. a preparation method for fruiting bodies of cordyceps militaris pressed candy, is characterized in that: it comprises the following steps:
1), ultramicro grinding: granularity≤25 μm of dried Cordyceps militaris being pulverized whole material to 90.0% through Ultra-Micro Grinding Equipment.
2), mixing granulation: by lactose, mannitol, maltodextrin and step 1) in Cordyceps militaris Ultramicro-powder by certain quality than Homogeneous phase mixing, then add water and granulate fast;
3), second time is dry: by step 2) obtained mixing wet granular carries out drying;
4), screening and whole grain: by step 3) dried hybrid particles sieves, the coarse granule on screen cloth, then carries out whole grain pulverizing;
5), mixing: by step 4) in hybrid particles and dolomol mix by a certain percentage, after mixing material wait until compressing tablet;
6), compressing tablet: by step 5) after mixing material carries out compressing tablet and obtains finished product.
2. the preparation method of fruiting bodies of cordyceps militaris pressed candy according to claim 1, is characterized in that: the recipe ingredient of described fruiting bodies of cordyceps militaris pressed candy comprises by mass percentage: Cordyceps militaris 20%-50%, lactose 10-50%, mannitol 2%-20%, maltodextrin 2%-20% and dolomol 0.3-3%.
3. the preparation method of fruiting bodies of cordyceps militaris pressed candy according to claim 1; it is characterized in that: in step 2) in, by lactose, mannitol, maltodextrin and step 4) in Cordyceps militaris Ultramicro-powder mass ratio equal increments method be according to a certain percentage placed in fast granulating machine and mix.
4. the preparation method of fruiting bodies of cordyceps militaris pressed candy according to claim 1, is characterized in that: in step 3) in, mixing wet granular is laid on pallet, the tiling thickness≤3cm of hybrid particles.
5. the preparation method of fruiting bodies of cordyceps militaris pressed candy according to claim 3, is characterized in that: in step 3) in, pallet is placed in hot air circulation drying oven, and arranging drying box temperature is 65-75 degree, dry 1.5-2.5 hour; Control moisture at 2%-3.5%.
6. the preparation method of fruiting bodies of cordyceps militaris pressed candy according to claim 1, is characterized in that: in step 4) in, material being poured into screen cloth is 20 object shaking screen extension sets, sieves in the operating room of humidity below 40%.
7. the preparation method of fruiting bodies of cordyceps militaris pressed candy according to claim 1, is characterized in that: in step 6) in, by after mixing material is put into tablet press machine and is carried out compressing tablet; Use electronic balance to carry out weight detecting to compressing tablet in tableting processes, control compressing tablet and focus on 550mg ± 50mg.
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Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104872365A (en) * | 2015-06-19 | 2015-09-02 | 陈政 | Tartary buckwheat dextrose candy and making method thereof |
| CN104887831A (en) * | 2015-06-19 | 2015-09-09 | 陈政 | Traditional Chinese medicine pressed candy and preparation method thereof |
| CN104920753A (en) * | 2015-06-19 | 2015-09-23 | 陈政 | Traditional Chinese medicine tabletting candy and preparation method thereof |
| CN105166295A (en) * | 2015-10-08 | 2015-12-23 | 广州市炜鑫生物科技有限公司 | Pressed candy rich in gamma-aminobutyric acid and cordyceps militaris and preparation method of pressed candy |
| CN105707381A (en) * | 2016-03-08 | 2016-06-29 | 陈夏风 | Defervescing sugar tablets for infants and preparation method thereof |
| CN105724717A (en) * | 2016-03-08 | 2016-07-06 | 陈夏风 | Sugar tablets with effects of invigorating stomach and removing dampness and preparation method of sugar tablets |
| CN105748579A (en) * | 2016-03-08 | 2016-07-13 | 陈夏风 | Sugar pills capable of increasing immunity and preparation method thereof |
| CN106035939A (en) * | 2016-05-10 | 2016-10-26 | 香格里拉东旺生物科技有限公司 | A nutritive healthcare cordyceps militaris polysaccharide pressed candy |
| CN106689619A (en) * | 2016-11-27 | 2017-05-24 | 山东华胶饮品有限公司 | Blood-enriching and skin-beautifying cordyceps militaris and ginseng tablet and preparation method thereof |
| CN107184684A (en) * | 2017-04-28 | 2017-09-22 | 孟江涛 | A kind of pressed candy of auxiliary treatment gout and preparation method thereof and application method |
| CN108208781A (en) * | 2017-12-29 | 2018-06-29 | 江苏康能生物工程股份有限公司 | A kind of reparation hepatic injury, the Cordyceps militaris composition and preparation method and application of strengthen immunity |
| CN109601676A (en) * | 2018-11-01 | 2019-04-12 | 防城港圣保堂制药有限公司 | A kind of ion Victoria C Chinese caterpillar fungus hypha pressed candy and preparation method thereof |
| CN110754556A (en) * | 2018-07-25 | 2020-02-07 | 天津健康美生物科技有限公司 | Processing technology of mixed instant tea preparation and tablet candy |
| CN112617082A (en) * | 2021-01-07 | 2021-04-09 | 天津市仁正慧和健康咨询服务有限公司 | Preparation method of cordyceps militaris tablet solid beverage with stable cordycepin content |
| CN114601009A (en) * | 2022-04-06 | 2022-06-10 | 常熟理工学院 | Silkworm chrysalis cordyceps sinensis tablet candy and preparation method thereof |
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Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104872365A (en) * | 2015-06-19 | 2015-09-02 | 陈政 | Tartary buckwheat dextrose candy and making method thereof |
| CN104887831A (en) * | 2015-06-19 | 2015-09-09 | 陈政 | Traditional Chinese medicine pressed candy and preparation method thereof |
| CN104920753A (en) * | 2015-06-19 | 2015-09-23 | 陈政 | Traditional Chinese medicine tabletting candy and preparation method thereof |
| CN105166295A (en) * | 2015-10-08 | 2015-12-23 | 广州市炜鑫生物科技有限公司 | Pressed candy rich in gamma-aminobutyric acid and cordyceps militaris and preparation method of pressed candy |
| CN105748579A (en) * | 2016-03-08 | 2016-07-13 | 陈夏风 | Sugar pills capable of increasing immunity and preparation method thereof |
| CN105724717A (en) * | 2016-03-08 | 2016-07-06 | 陈夏风 | Sugar tablets with effects of invigorating stomach and removing dampness and preparation method of sugar tablets |
| CN105707381A (en) * | 2016-03-08 | 2016-06-29 | 陈夏风 | Defervescing sugar tablets for infants and preparation method thereof |
| CN106035939A (en) * | 2016-05-10 | 2016-10-26 | 香格里拉东旺生物科技有限公司 | A nutritive healthcare cordyceps militaris polysaccharide pressed candy |
| CN106689619A (en) * | 2016-11-27 | 2017-05-24 | 山东华胶饮品有限公司 | Blood-enriching and skin-beautifying cordyceps militaris and ginseng tablet and preparation method thereof |
| CN107184684A (en) * | 2017-04-28 | 2017-09-22 | 孟江涛 | A kind of pressed candy of auxiliary treatment gout and preparation method thereof and application method |
| CN108208781A (en) * | 2017-12-29 | 2018-06-29 | 江苏康能生物工程股份有限公司 | A kind of reparation hepatic injury, the Cordyceps militaris composition and preparation method and application of strengthen immunity |
| CN110754556A (en) * | 2018-07-25 | 2020-02-07 | 天津健康美生物科技有限公司 | Processing technology of mixed instant tea preparation and tablet candy |
| CN109601676A (en) * | 2018-11-01 | 2019-04-12 | 防城港圣保堂制药有限公司 | A kind of ion Victoria C Chinese caterpillar fungus hypha pressed candy and preparation method thereof |
| CN112617082A (en) * | 2021-01-07 | 2021-04-09 | 天津市仁正慧和健康咨询服务有限公司 | Preparation method of cordyceps militaris tablet solid beverage with stable cordycepin content |
| CN114601009A (en) * | 2022-04-06 | 2022-06-10 | 常熟理工学院 | Silkworm chrysalis cordyceps sinensis tablet candy and preparation method thereof |
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Application publication date: 20150527 |