CN104623913A - Chinese medicinal granular concentration process vacuum degree stability control device and Chinese medicinal granular concentration process vacuum degree stability control method - Google Patents
Chinese medicinal granular concentration process vacuum degree stability control device and Chinese medicinal granular concentration process vacuum degree stability control method Download PDFInfo
- Publication number
- CN104623913A CN104623913A CN201410817596.4A CN201410817596A CN104623913A CN 104623913 A CN104623913 A CN 104623913A CN 201410817596 A CN201410817596 A CN 201410817596A CN 104623913 A CN104623913 A CN 104623913A
- Authority
- CN
- China
- Prior art keywords
- pressure sensor
- chinese medicinal
- accumulator
- concentration process
- vacuum degree
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
Abstract
The invention discloses a Chinese medicinal granular concentration process vacuum degree stability control device and a Chinese medicinal granular concentration process vacuum degree stability control method. After a liquid receiving device is emptied, a first pressure sensor is started by a control system, a vacuum degree in the liquid receiving device is detected by virtue of the first pressure sensor, a detection result is fed back to the control system, the control system controls the openness of an automatic regulation valve according to the detection result, meanwhile, a steam quantity of an evaporation concentrator is also adjusted, and the temperature of the evaporation concentrator is maintained stable. By adopting the Chinese medicinal granular concentration process vacuum degree stability control device and the Chinese medicinal granular concentration process vacuum degree stability control method, the vacuum degree and temperature fluctuation in a concentration system can be reduced by controlling the openness of the automatic regulation valve and the steam quantity of the evaporation concentrator, so that various defects and weaknesses in the existing concentration process can be overcome, and the concentration time and the energy consumption can be greatly saved.
Description
Technical field
The present invention relates to field of traditional Chinese medicine pharmacy, particularly relate to a kind of Chinese medicinal granule concentration process vacustat control device and method.
Background technology
Chinese medicinal granule pharmaceutical technology flow process is generally: medicinal material pre-treatment (gather-clean-dry)-extraction-separation-purifying-(pulverizing)-screen analysis-mixing-granulation.Wherein concentration process is the important step that Chinese medicinal granule is produced, and plays an important role to the security, validity, stability etc. of final products.In concentration process, traditional method of operating is when the solvent liquid level accepted in accumulator arrives about 2/3rds, needs emptying rate of liquid in accumulator.In accumulator, emptying rate of liquid needs the connection valve of first closing between accumulator and cooler, opens the atmospheric valve of accumulator, makes accumulator recover atmospheric pressure state, then that accumulator is emptying; After emptying, close atmospheric valve, open the connection valve between accumulator and cooler, continue to accept condensate liquid.
The defect of conventional method is, after accumulator is emptying, pressure in accumulator is normal pressure, and be vacuum state in condenser and evaporation concentrator, the aperture of the connection valve between accumulator and cooler is uncontrollable, after opening valve, greatly can reduce the vacuum of vacuum concentration system moment.Recover vacuum needed for evaporation and concentration and then need the long period, internal solvent cannot be distilled out during this period of time, and during this period of time in vacuum system and steam-heating system in running order, thus cause energy consumption and waste of time.The heat provided due to steam can not be taken away in time, and the temperature of charge in evaporation concentrator raises, and simultaneously owing to extending the Vacuum Concentration time, likely causes the heat-sensitive ingredients of active ingredient to decompose, thus reduces drug effect, even affect product quality.In traditional Chinese drug inspissation process, vacustat is kept to be letter technical barrier to be solved.
Summary of the invention
The technical problem that the present invention mainly solves is to provide a kind of Chinese medicinal granule concentration process vacustat control device and method, and these apparatus and method save concentration time and energy consumption.
For solving the problems of the technologies described above, the technical scheme that the present invention adopts is: provide a kind of Chinese medicinal granule concentration process vacustat control device, concentration process carries out in vacuum concentration system, described vacuum concentration system comprises evaporation concentrator, cooler and accumulator, described device comprises the first pressure sensor, automatic regulating valve, control system, described first pressure sensor is arranged in described accumulator, described automatic regulating valve is between described cooler and described accumulator, described first pressure sensor, described automatic regulating valve is electrically connected with described control system respectively.
In a preferred embodiment of the present invention, also comprise the second pressure sensor, described second pressure sensor is arranged in described evaporation concentrator, and described second pressure sensor and described control system are electrically connected.
In a preferred embodiment of the present invention, described evaporation concentrator is efficient concentration device, haplo-effect concentrator or dual-effect concentrator.
A kind of Chinese medicinal granule concentration process vacustat control method is provided, comprising step is: after accumulator is emptying, control system starts the first pressure sensor, described first pressure sensor detects the vacuum in accumulator, testing result is fed back to described control system, and described control system controls the aperture of automatic regulating valve according to testing result.
In a preferred embodiment of the present invention, if when the fluctuation vacuum of described vacuum concentration system is greater than 4.5%, described control system turns the aperture of described automatic regulating valve down.
In a preferred embodiment of the present invention, if when the fluctuation vacuum of described vacuum concentration system is less than 2%, described control system tunes up the aperture of described automatic regulating valve.
In a preferred embodiment of the present invention, when described first pressure sensor is identical with the testing result of described second pressure sensor, the aperture of described automatic regulating valve is 100%.
In a preferred embodiment of the present invention, described control method also comprises the quantity of steam regulating evaporation concentrator, maintains evaporation concentrator temperature stabilization.
The invention has the beneficial effects as follows: Chinese medicinal granule concentration process vacustat control device of the present invention and method, by controlling the aperture of automatic regulating valve and the quantity of steam of evaporation concentrator, reduce the vacuum in concentration systems and temperature fluctuation, thus overcome many defects and the deficiency of the existence of existing concentration process, greatly save concentration time and energy consumption.
Accompanying drawing explanation
In order to be illustrated more clearly in the technical scheme in the embodiment of the present invention, below the accompanying drawing used required in describing embodiment is briefly described, apparently, accompanying drawing in the following describes is only some embodiments of the present invention, for those of ordinary skill in the art, under the prerequisite not paying creative work, other accompanying drawing can also be obtained according to these accompanying drawings, wherein:
Fig. 1 is the structural representation of vacuum concentration system of the present invention.
Detailed description of the invention
Be clearly and completely described to the technical scheme in the embodiment of the present invention below, obviously, described embodiment is only a part of embodiment of the present invention, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making other embodiments all obtained under creative work prerequisite, belong to the scope of protection of the invention.
Refer to Fig. 1, the embodiment of the present invention comprises:
A kind of Chinese medicinal granule concentration process vacustat control device, concentration process carries out in vacuum concentration system, described vacuum concentration system comprises evaporation concentrator 1, cooler 2 and accumulator 3, and described evaporation concentrator 1 is efficient concentration device, haplo-effect concentrator or dual-effect concentrator.Described device comprises the first pressure sensor, the second pressure sensor, automatic regulating valve, control system, described first pressure sensor is arranged in described accumulator, described second pressure sensor is arranged in described evaporation concentrator, connection valve between described cooler and described accumulator is automatic regulating valve, and described first pressure sensor, described second pressure sensor and described automatic regulating valve are electrically connected with described control system respectively.
Adopt the method that Chinese medicinal granule concentration process vacustat control device carries out, comprising step is: when accumulator needs are emptying, closes the automatic regulating valve between cooler and accumulator, opens the atmospheric valve of accumulator, emptying accumulator, cuts out the atmospheric valve of accumulator; Control system starts the first pressure sensor, described first pressure sensor detects the vacuum in accumulator, testing result is fed back to described control system, described control system controls the aperture of automatic regulating valve, to control the fluctuation vacuum of described vacuum concentration system within the specific limits according to testing result.If when the fluctuation vacuum of described vacuum concentration system is greater than 4.5%, described control system turns the aperture of described automatic regulating valve down.If when the fluctuation vacuum of described vacuum concentration system is less than 2%, described control system tunes up the aperture of described automatic regulating valve.When the vacuum of accumulator and the vacuum of evaporation concentration system are consistent, all opened by automatic regulating valve, aperture is 100%.Keep the vacuum of vacuum concentration system and temperature fluctuation lower than 5% in whole process.
Controlling model between the technological parameters such as design vacuum, valve opening, quantity of steam, control system receiving process parameter, and according to model controlling opening of valve and quantity of steam, realize the control to concentration process vacustat.
Extracting honeysuckle medicine materical crude slice 100 Kg adds water after 600 Kg flood 30 minutes, and decoct secondary, each 1 hour, gradation filters, and merging filtrate, at 65 ~ 75 DEG C, Vacuum Concentration to relative density is 1.20 ~ 1.25 g/ml.
1, conventional method
When the solvent liquid level accepted in accumulator arrives about 2/3rds, close the connection valve between accumulator 3 and cooler 2, open the atmospheric valve of accumulator, accumulator 3 recovers atmospheric pressure state, then by emptying for accumulator 3; Open the connection valve between accumulator 3 and cooler 2, the vacuum of evaporation concentration system is down to-0.03 ~-0.04 MPa instantaneously, and fluctuation vacuum is very large, records the vacuum of flush distillation concentration systems and the temperature of inspissator every 5 min, test in triplicate, the results are shown in following table.
2, method of the present invention
When accumulator 3 needs emptying, close the automatic regulating valve between cooler 2 and accumulator 3, open the atmospheric valve of accumulator 3, emptying accumulator, close the atmospheric valve of accumulator, open the automatic regulating valve between cooler 2 and accumulator 3, the aperture of control valve, make the fluctuation vacuum of evaporation concentration system lower than 5%, regulate the quantity of steam of evaporation concentrator simultaneously, maintain evaporation concentrator temperature fluctuation lower than 5%, when being consistent to the vacuum of accumulator 3 and the vacuum of evaporation concentration system, automatic regulating valve is all opened.
Record the vacuum of flush distillation concentration systems, the vacuum of accumulator 3 and the temperature of inspissator every 5min, test in triplicate, result following table;
From experimental result comparison, a kind of Chinese medicinal granule concentration process vacustat control device of the present invention and method, by controlling the aperture of automatic regulating valve and the quantity of steam of evaporation concentrator, control the vacuum of system and the stability of temperature, the fluctuation of vacuum, lower than 5%, compared with conventional method, has clear superiority, effectively can maintain the stable of vacuum in concentration process, save concentration time simultaneously and save energy consumption.
The foregoing is only embodiments of the invention; not thereby the scope of the claims of the present invention is limited; every utilize description of the present invention to do equivalent structure or equivalent flow process conversion; or be directly or indirectly used in other relevant technical field, be all in like manner included in scope of patent protection of the present invention.
Claims (8)
1. a Chinese medicinal granule concentration process vacustat control device, concentration process carries out in vacuum concentration system, described vacuum concentration system comprises evaporation concentrator, cooler and accumulator, it is characterized in that, described device comprises the first pressure sensor, automatic regulating valve, control system, described first pressure sensor is arranged in described accumulator, described automatic regulating valve is between described cooler and described accumulator, and described first pressure sensor, described automatic regulating valve are electrically connected with described control system respectively.
2. control device according to claim 1, is characterized in that, also comprises the second pressure sensor, and described second pressure sensor is arranged in described evaporation concentrator, and described second pressure sensor and described control system are electrically connected.
3. control device according to claim 1, is characterized in that, described evaporation concentrator is efficient concentration device, haplo-effect concentrator or dual-effect concentrator.
4. a kind of Chinese medicinal granule concentration process vacustat control method is provided, it is characterized in that, comprising step is: after accumulator is emptying, control system starts the first pressure sensor, described first pressure sensor detects the vacuum in accumulator, testing result is fed back to described control system, and described control system controls the aperture of automatic regulating valve according to testing result.
5. control method according to claim 4, is characterized in that, if when the fluctuation vacuum of described vacuum concentration system is greater than 4.5%, described control system turns the aperture of described automatic regulating valve down.
6. control method according to claim 4, is characterized in that, if when the fluctuation vacuum of described vacuum concentration system is less than 2%, described control system tunes up the aperture of described automatic regulating valve.
7. control method according to claim 4, is characterized in that, when described first pressure sensor is identical with the testing result of described second pressure sensor, the aperture of described automatic regulating valve is 100%.
8. control method according to claim 4, is characterized in that, also comprises the quantity of steam regulating evaporation concentrator, maintains evaporation concentrator temperature stabilization.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410817596.4A CN104623913B (en) | 2014-12-25 | 2014-12-25 | A kind of Chinese medicinal granule concentration process vacustat control device and method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410817596.4A CN104623913B (en) | 2014-12-25 | 2014-12-25 | A kind of Chinese medicinal granule concentration process vacustat control device and method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104623913A true CN104623913A (en) | 2015-05-20 |
| CN104623913B CN104623913B (en) | 2016-04-20 |
Family
ID=53203444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410817596.4A Active CN104623913B (en) | 2014-12-25 | 2014-12-25 | A kind of Chinese medicinal granule concentration process vacustat control device and method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104623913B (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6254734B1 (en) * | 1995-03-14 | 2001-07-03 | Hugo H Sephton | Barometric evaporation process and evaporator |
| CN2544780Y (en) * | 2002-05-10 | 2003-04-16 | 郑加福 | Automatic draiage concentrator |
| CN103301640A (en) * | 2013-07-10 | 2013-09-18 | 佛山德众药业有限公司 | Concentration method and device for traditional Chinese medicine extracting solution |
| CN203389342U (en) * | 2013-07-10 | 2014-01-15 | 佛山德众药业有限公司 | Concentration device of traditional Chinese medicine extracting solution |
-
2014
- 2014-12-25 CN CN201410817596.4A patent/CN104623913B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6254734B1 (en) * | 1995-03-14 | 2001-07-03 | Hugo H Sephton | Barometric evaporation process and evaporator |
| CN2544780Y (en) * | 2002-05-10 | 2003-04-16 | 郑加福 | Automatic draiage concentrator |
| CN103301640A (en) * | 2013-07-10 | 2013-09-18 | 佛山德众药业有限公司 | Concentration method and device for traditional Chinese medicine extracting solution |
| CN203389342U (en) * | 2013-07-10 | 2014-01-15 | 佛山德众药业有限公司 | Concentration device of traditional Chinese medicine extracting solution |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104623913B (en) | 2016-04-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN202819529U (en) | Steam jet type soybean anti-nutritional factor inactivation device | |
| CN103408473B (en) | A kind of method extracting natural taurine from scallop splanchna | |
| CN105536274A (en) | Control method for double-effect concentration process of Chinese traditional medicines | |
| EP2786988A1 (en) | Method for manufacturing monosaccharides, oligosaccharides, and furfurals from biomass | |
| US20190112254A1 (en) | Method of producing hydroxycinnamic acids | |
| CN108513633A (en) | A kind of extracts of Chinese herbal medicine concentration intelligent control system | |
| CN203233992U (en) | Soy sauce fermentation bin | |
| CN104623913B (en) | A kind of Chinese medicinal granule concentration process vacustat control device and method | |
| CN102351929B (en) | Preparation method of high-purity breviscapine active pharmaceutical ingredient | |
| CN104524790B (en) | A kind of Chinese medicinal granule concentration process maintains the device and method of vacustat | |
| CN203458833U (en) | Continuous extracting, concentrating and drying production line | |
| CN107056741A (en) | A kind of preparation technology of Application of Mulberry Anthocyanins powder | |
| CN104193668B (en) | Macroporous resin extracts the method for L-Trp in fermented liquid | |
| CN204034314U (en) | A kind of gluconic acid sodium salt crystallization apparatus | |
| CN204752740U (en) | Plant micro molecule peptide powder production facility | |
| CN203507559U (en) | Nature-imitated honey thickener | |
| CN111792687B (en) | Heat supply network drainage waste heat recovery device and method for thermal power plant based on sea water desalination technology | |
| CN207871568U (en) | A kind of gynostemma pentaphyllum extracting solution high-efficiency scraper enrichment facility | |
| CN101293862A (en) | Method for preparing high content monosultap and dimehypo with monosultap anticentripetal mother solution | |
| CN105832660A (en) | Refining technology of traditional Chinese medicine injection | |
| CN104724891B (en) | A kind of processing method of oxytetracycline crystallization mother liquor waste water | |
| CN205258404U (en) | Automatic device extracts oil | |
| CN202575288U (en) | Camellia seed blanking device | |
| CN209314788U (en) | A kind of bean curd control pond | |
| CN205148843U (en) | Twin -screw is extruded with vacuum system and double screw extruder |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |