CN105832660A - Refining technology of traditional Chinese medicine injection - Google Patents
Refining technology of traditional Chinese medicine injection Download PDFInfo
- Publication number
- CN105832660A CN105832660A CN201610275723.1A CN201610275723A CN105832660A CN 105832660 A CN105832660 A CN 105832660A CN 201610275723 A CN201610275723 A CN 201610275723A CN 105832660 A CN105832660 A CN 105832660A
- Authority
- CN
- China
- Prior art keywords
- medicinal liquid
- chinese medicine
- refining
- sterilizing
- filter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F9/00—Multistage treatment of water, waste water or sewage
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/001—Processes for the treatment of water whereby the filtration technique is of importance
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/22—Treatment of water, waste water, or sewage by freezing
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/40—Devices for separating or removing fatty or oily substances or similar floating material
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/44—Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/66—Treatment of water, waste water, or sewage by neutralisation; pH adjustment
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2303/00—Specific treatment goals
- C02F2303/04—Disinfection
Abstract
The invention provides a refining technology of a traditional Chinese medicine injection .The technology comprises the steps that liquid medicine is subjected to impurity removing and oil removing and initial filtration and then delivered into a refining tank, the PH value is adjusted, filtration is conducted again, impurities are prevented from entering the injection, and sterilization is conducted at last .The safety performance of the injection is improved, and the problems that when the traditional Chinese medicine injection is refined, filtration is incomplete, and the impurities are prone to be mixed in are solved.
Description
Technical field
The present invention relates to Chinese crude drug treatment field, particularly relate to the process for refining of a kind of Chinese medicine.
Background technology
At present the most in the mill medicine injection time, after needing Chinese crude drug is carried out percolation and then refine, to ensure the quality of injection.When at present carrying out refined for Chinese crude drug, it is common that it is also filtered by the simple pH value that adjusts, but the refined medicinal liquid that aforesaid way is made can not reach best in effect, and easily cause the waste of medicinal liquid and impurity enters.Therefore, solve Chinese medicine to filter when refining and not exclusively and be easily mixed into the problem of impurity and be just particularly important.
Summary of the invention
The problem existed for above-mentioned prior art, it is an object of the invention to provide the process for refining of a kind of Chinese medicine, by remove impurity oil removing, and send into treatment tank after first filtration, again filter after regulation pH value, it is to avoid impurity enters in injection, carries out sterilization treatment the most again, increase the security performance of injection, solve the problem that when Chinese medicine refines, filtration not exclusively and is easily mixed into impurity.
The present invention provides the process for refining of a kind of Chinese medicine, and described process for refining step is as follows:
Step one: go cold preservation medicinal liquid to process the medicinal liquid after receiving cream；
Step 2: carry out medicinal liquid removing upper strata floating oil；
Step 3: medicinal liquid is filtered to treatment tank by plate filter；
Step 4: use sodium hydroxide to carry out medicinal liquid adjusting pH value to process, and add sodium chloride；
Step 5: medicinal liquid is stirred, uniformly after filter through filter membrane；
Step 6: in medicinal liquid nitrogen charging subpackage to 500ml infusion bottle；
Step 7: infusion bottle is delivered to carry out in quick cooling sterilizing case sterilizing, to Cold storage in the refrigerator one week after sterilizing.
Further improvement is that: in described step 3, the aperture of the filter membrane of plate filter is 0.45 μm.
Further improvement is that: medicinal liquid is carried out by described step 4 during pH value regulation, the pH value of medicinal liquid is adjusted to 8-9.
Further improvement is that: in described five, the aperture of filter membrane is 0.45 μm.
Further improvement is that: in described step 7, the temperature of sterilizing is 105 DEG C, sterilization time is 40 minutes.
The invention has the beneficial effects as follows: by remove impurity oil removing, and send into treatment tank after first filtration, again filter after regulation pH value, impurity is avoided to enter in injection, finally carry out sterilization treatment again, increase the security performance of injection, solve the problem that when Chinese medicine refines, filtration not exclusively and is easily mixed into impurity.
Detailed description of the invention
In order to deepen the understanding of the present invention, below in conjunction with embodiment, the invention will be further described, and this embodiment is only used for explaining the present invention, is not intended that limiting the scope of the present invention.
Present embodiments providing the process for refining of a kind of Chinese medicine, described process for refining step is as follows:
Step one: go cold preservation medicinal liquid to process the medicinal liquid after receiving cream；
Step 2: carry out medicinal liquid removing upper strata floating oil；
Step 3: medicinal liquid is filtered to treatment tank by plate filter；
Step 4: use sodium hydroxide to carry out medicinal liquid adjusting pH value to process, and add sodium chloride；
Step 5: medicinal liquid is stirred, uniformly after filter through filter membrane；
Step 6: in medicinal liquid nitrogen charging subpackage to 500ml infusion bottle；
Step 7: infusion bottle is delivered to carry out in quick cooling sterilizing case sterilizing, to Cold storage in the refrigerator one week after sterilizing.
In described step 3, the aperture of the filter membrane of plate filter is 0.45 μm.It is 0.45 μm that medicinal liquid carries out in described step 4 being adjusted to by the pH value of medicinal liquid during pH value regulation described in 8. the aperture of filter membrane in five.In described step 7, the temperature of sterilizing is 105 DEG C, and sterilization time is 40 minutes.
By remove impurity oil removing, and after first filtration, send into treatment tank, again filter after regulation pH value, impurity is avoided to enter in injection, the last sterilization treatment that carries out again, the security performance of increase injection, solve the problem that when Chinese medicine refines, filtration not exclusively and is easily mixed into impurity.
Claims (5)
1. the process for refining of a Chinese medicine, it is characterised in that: described process for refining step is as follows:
Step one: go cold preservation medicinal liquid to process the medicinal liquid after receiving cream；
Step 2: carry out medicinal liquid removing upper strata floating oil；
Step 3: medicinal liquid is filtered to treatment tank by plate filter；
Step 4: use sodium hydroxide to carry out medicinal liquid adjusting pH value to process, and add sodium chloride；
Step 5: medicinal liquid is stirred, uniformly after filter through filter membrane；
Step 6: in medicinal liquid nitrogen charging subpackage to 500ml infusion bottle；
Step 7: infusion bottle is delivered to carry out in quick cooling sterilizing case sterilizing, to Cold storage in the refrigerator one week after sterilizing.
2. the process for refining of Chinese medicine as claimed in claim 1, it is characterised in that: in described step 3, the aperture of the filter membrane of plate filter is 0.45 μm.
3. the process for refining of Chinese medicine as claimed in claim 1, it is characterised in that: medicinal liquid is carried out by described step 4 during pH value regulation, the pH value of medicinal liquid is adjusted to 8-9.
4. the process for refining of Chinese medicine as claimed in claim 1, it is characterised in that: in described five, the aperture of filter membrane is 0.45 μm.
5. the process for refining of Chinese medicine as claimed in claim 1, it is characterised in that: in described step 7, the temperature of sterilizing is 105 DEG C, and sterilization time is 40 minutes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610275723.1A CN105832660A (en) | 2016-04-29 | 2016-04-29 | Refining technology of traditional Chinese medicine injection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610275723.1A CN105832660A (en) | 2016-04-29 | 2016-04-29 | Refining technology of traditional Chinese medicine injection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105832660A true CN105832660A (en) | 2016-08-10 |
Family
ID=56589472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610275723.1A Pending CN105832660A (en) | 2016-04-29 | 2016-04-29 | Refining technology of traditional Chinese medicine injection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105832660A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107582591A (en) * | 2017-09-30 | 2018-01-16 | 芜湖杨燕制药有限公司 | A kind of insect-expelling saligna injection liquid decoction process for refining |
| CN107814009A (en) * | 2017-09-29 | 2018-03-20 | 芜湖杨燕制药有限公司 | A kind of transfusion bottle during sterilization method in traditional Chinese medicine production |
-
2016
- 2016-04-29 CN CN201610275723.1A patent/CN105832660A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107814009A (en) * | 2017-09-29 | 2018-03-20 | 芜湖杨燕制药有限公司 | A kind of transfusion bottle during sterilization method in traditional Chinese medicine production |
| CN107582591A (en) * | 2017-09-30 | 2018-01-16 | 芜湖杨燕制药有限公司 | A kind of insect-expelling saligna injection liquid decoction process for refining |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160810 |